CN1270714C - 含哌啶物质p拮抗剂的微乳液预浓缩物 - Google Patents

含哌啶物质p拮抗剂的微乳液预浓缩物 Download PDF

Info

Publication number
CN1270714C
CN1270714C CNB998066036A CN99806603A CN1270714C CN 1270714 C CN1270714 C CN 1270714C CN B998066036 A CNB998066036 A CN B998066036A CN 99806603 A CN99806603 A CN 99806603A CN 1270714 C CN1270714 C CN 1270714C
Authority
CN
China
Prior art keywords
composition
pharmaceutical composition
total weight
compositions
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB998066036A
Other languages
English (en)
Chinese (zh)
Other versions
CN1303285A (zh
Inventor
S·兰格
K·莱克特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9811200.6A external-priority patent/GB9811200D0/en
Priority claimed from GBGB9818105.0A external-priority patent/GB9818105D0/en
Application filed by Novartis AG filed Critical Novartis AG
Publication of CN1303285A publication Critical patent/CN1303285A/zh
Application granted granted Critical
Publication of CN1270714C publication Critical patent/CN1270714C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB998066036A 1998-05-26 1999-05-26 含哌啶物质p拮抗剂的微乳液预浓缩物 Expired - Fee Related CN1270714C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9811200.6A GB9811200D0 (en) 1998-05-26 1998-05-26 Organic compounds
GB9811200.6 1998-05-26
GB9818105.0 1998-08-19
GBGB9818105.0A GB9818105D0 (en) 1998-08-19 1998-08-19 Organic compounds

Publications (2)

Publication Number Publication Date
CN1303285A CN1303285A (zh) 2001-07-11
CN1270714C true CN1270714C (zh) 2006-08-23

Family

ID=26313736

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998066036A Expired - Fee Related CN1270714C (zh) 1998-05-26 1999-05-26 含哌啶物质p拮抗剂的微乳液预浓缩物

Country Status (30)

Country Link
US (2) US20020156099A1 (https=)
EP (1) EP1082119B1 (https=)
JP (1) JP4083985B2 (https=)
KR (1) KR20010043669A (https=)
CN (1) CN1270714C (https=)
AR (1) AR018376A1 (https=)
AT (1) ATE257380T1 (https=)
AU (1) AU755134B2 (https=)
BE (1) BE1012143A5 (https=)
BR (1) BR9910696A (https=)
CA (1) CA2333154C (https=)
DE (2) DE69914077T2 (https=)
DK (1) DK1082119T3 (https=)
ES (1) ES2214859T3 (https=)
FR (1) FR2779145B1 (https=)
GB (1) GB2353473A (https=)
HU (1) HUP0102202A3 (https=)
ID (1) ID27096A (https=)
IL (1) IL139501A0 (https=)
IT (1) IT1313551B1 (https=)
NO (1) NO20005920L (https=)
NZ (1) NZ508325A (https=)
PE (1) PE20000537A1 (https=)
PL (1) PL344245A1 (https=)
PT (1) PT1082119E (https=)
RU (1) RU2240121C2 (https=)
SK (1) SK17752000A3 (https=)
TR (1) TR200003502T2 (https=)
TW (1) TW537894B (https=)
WO (1) WO1999061025A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR018376A1 (es) 1998-05-26 2001-11-14 Novartis Ag Composiciones farmaceuticas que se pueden dispersar de una manera espontanea y el uso de las mismas para la manufactura de un medicamento
US7202282B2 (en) * 2002-04-22 2007-04-10 University Of Florida Microemulsions for selective molecular separation
GB0220953D0 (en) * 2002-09-10 2002-10-23 Novartis Ag Organic compounds
US7842791B2 (en) 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
FR2935001B1 (fr) * 2008-08-14 2011-12-30 Commissariat Energie Atomique Emulsion fluorescente
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
FR2934955B1 (fr) 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
FR2934953B1 (fr) 2008-08-14 2011-01-21 Commissariat Energie Atomique Nanoemulsions de nanocristaux
WO2014106048A2 (en) * 2012-12-31 2014-07-03 Jrx Biotechnology, Inc. Liquid topical pharmaceutical nano-emulsion formulations

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3305689A1 (de) 1983-02-18 1984-08-23 Mack Chem Pharm Pharmazeutische zubereitung mit retardwirkung
US5342625A (en) * 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
MY110227A (en) 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
DE4220616C2 (de) 1992-06-24 1994-12-22 Byk Gulden Lomberg Chem Fab Dexniguldipin zur intravenösen Verabreichung
EP1142568A1 (en) 1992-09-25 2001-10-10 Novartis AG Pharmaceutical compositions containing cyclosporins
GB2278780B (en) * 1993-05-27 1998-10-14 Sandoz Ltd Macrolide formulations
ES2270426T3 (es) * 1994-03-18 2007-04-01 Supernus Pharmaceuticals, Inc. Sistema de suministros de farmacos emulsionados.
TW397825B (en) * 1994-10-14 2000-07-11 Novartis Ag Aroyl-piperidine derivatives
GB2308545B (en) 1994-10-26 1999-06-02 Novartis Ag Pharmaceutical microemulsion preconcentrates
PE52896A1 (es) * 1994-10-26 1996-12-12 Novartis Ag Composicion farmaceutica
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
ATE209204T1 (de) 1995-03-27 2001-12-15 Hisamitsu Pharmaceutical Co Piperidinderivate.
NZ280689A (en) 1995-12-15 1997-08-22 Bernard Charles Sherma Sherman Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol
GB9601120D0 (en) 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
AU2898297A (en) 1996-05-24 1998-01-05 Novartis Ag Use of substance p antagonists for treating social phobia
AR018376A1 (es) 1998-05-26 2001-11-14 Novartis Ag Composiciones farmaceuticas que se pueden dispersar de una manera espontanea y el uso de las mismas para la manufactura de un medicamento

Also Published As

Publication number Publication date
IT1313551B1 (it) 2002-09-09
AU4500899A (en) 1999-12-13
ITMI991164A1 (it) 2000-11-26
EP1082119B1 (en) 2004-01-07
IL139501A0 (en) 2001-11-25
TW537894B (en) 2003-06-21
EP1082119A1 (en) 2001-03-14
AR018376A1 (es) 2001-11-14
ES2214859T3 (es) 2004-09-16
CA2333154A1 (en) 1999-12-02
JP4083985B2 (ja) 2008-04-30
US20030152626A1 (en) 2003-08-14
NZ508325A (en) 2003-06-30
HK1035137A1 (en) 2001-11-16
HUP0102202A3 (en) 2003-01-28
PT1082119E (pt) 2004-05-31
AU755134B2 (en) 2002-12-05
SK17752000A3 (sk) 2001-05-10
RU2240121C2 (ru) 2004-11-20
KR20010043669A (ko) 2001-05-25
GB0028506D0 (en) 2001-01-10
JP2002516280A (ja) 2002-06-04
CA2333154C (en) 2008-07-08
BR9910696A (pt) 2001-01-30
HUP0102202A2 (hu) 2001-11-28
ATE257380T1 (de) 2004-01-15
US6949257B2 (en) 2005-09-27
TR200003502T2 (tr) 2001-04-20
WO1999061025A1 (en) 1999-12-02
NO20005920D0 (no) 2000-11-23
FR2779145B1 (fr) 2004-07-30
BE1012143A5 (fr) 2000-05-02
CN1303285A (zh) 2001-07-11
PL344245A1 (en) 2001-10-08
ID27096A (id) 2001-03-01
DK1082119T3 (da) 2004-04-13
PE20000537A1 (es) 2000-07-10
DE19983247T1 (de) 2001-05-31
GB2353473A (en) 2001-02-28
NO20005920L (no) 2001-01-25
FR2779145A1 (fr) 1999-12-03
DE69914077D1 (de) 2004-02-12
US20020156099A1 (en) 2002-10-24
DE69914077T2 (de) 2004-06-09

Similar Documents

Publication Publication Date Title
CN1124157C (zh) 药物组合物
JP5792299B2 (ja) 神経因性疼痛の治療のための６’−フルオロ−（Ｎ−メチル−又はＮ，Ｎ−ジメチル−）−４−フェニル−４’，９’−ジヒドロ−３’Ｈ−スピロ［シクロヘキサン−１，１’−ピラノ［３，４，ｂ］インドール］−４−アミンを含む医薬剤形
US6432445B1 (en) Pharmaceutical capsules comprising a cyclosporin
JP5057610B2 (ja) 自然分散性ｎ−ベンゾイルスタウロスポリン組成物
CN1270714C (zh) 含哌啶物质p拮抗剂的微乳液预浓缩物
CN1559407A (zh) 二氢吡啶类钙离子拮抗剂的自微乳化软胶囊及其制备方法
RU2397759C2 (ru) Микроэмульсионные композиции, включающие антагонисты вещества р
CZ20004355A3 (cs) Farmaceutický přípravek
ZA200006597B (en) Microemulsion preconcentrates containing a piperidine substance p antagonist.
MXPA00011581A (en) Microemulsion preconcentrates containing a piperidine substance p antagonist
HK1035137B (en) Microemulsion preconcentrates containing a piperidine substance p antagonist
KR20070018003A (ko) 특정 물질 ｐ 길항제를 포함하는 마이크로에멀젼 제제
MXPA06008856A (en) Microemulsion formulations comprising particular substance p antagonists

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20060823

Termination date: 20110526