CN1217648A - Dispenser unit, process for manufacturing same and its use - Google Patents

Dispenser unit, process for manufacturing same and its use Download PDF

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Publication number
CN1217648A
CN1217648A CN97194437A CN97194437A CN1217648A CN 1217648 A CN1217648 A CN 1217648A CN 97194437 A CN97194437 A CN 97194437A CN 97194437 A CN97194437 A CN 97194437A CN 1217648 A CN1217648 A CN 1217648A
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CN
China
Prior art keywords
bag
internal layer
polyethylene
transport box
connector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN97194437A
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Chinese (zh)
Inventor
冈瑟·斯特拉斯曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sengewald Verpackungen GmbH
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Sengewald Verpackungen GmbH
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Publication date
Application filed by Sengewald Verpackungen GmbH filed Critical Sengewald Verpackungen GmbH
Publication of CN1217648A publication Critical patent/CN1217648A/en
Pending legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/14—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B29C65/4805—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the type of adhesives
    • B29C65/481—Non-reactive adhesives, e.g. physically hardening adhesives
    • B29C65/4815—Hot melt adhesives, e.g. thermoplastic adhesives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B29C65/50—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding using adhesive tape, e.g. thermoplastic tape; using threads or the like
    • B29C65/5057—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding using adhesive tape, e.g. thermoplastic tape; using threads or the like positioned between the surfaces to be joined
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/01—General aspects dealing with the joint area or with the area to be joined
    • B29C66/05—Particular design of joint configurations
    • B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/11—Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
    • B29C66/112—Single lapped joints
    • B29C66/1122—Single lap to lap joints, i.e. overlap joints
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/01—General aspects dealing with the joint area or with the area to be joined
    • B29C66/05—Particular design of joint configurations
    • B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/13—Single flanged joints; Fin-type joints; Single hem joints; Edge joints; Interpenetrating fingered joints; Other specific particular designs of joint cross-sections not provided for in groups B29C66/11 - B29C66/12
    • B29C66/133—Fin-type joints, the parts to be joined being flexible
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/01—General aspects dealing with the joint area or with the area to be joined
    • B29C66/05—Particular design of joint configurations
    • B29C66/20—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines
    • B29C66/24—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being closed or non-straight
    • B29C66/242—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being closed or non-straight said joint lines being closed, i.e. forming closed contours
    • B29C66/2422—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being closed or non-straight said joint lines being closed, i.e. forming closed contours being circular, oval or elliptical
    • B29C66/24221—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being closed or non-straight said joint lines being closed, i.e. forming closed contours being circular, oval or elliptical being circular
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/53—Joining single elements to tubular articles, hollow articles or bars
    • B29C66/532—Joining single elements to the wall of tubular articles, hollow articles or bars
    • B29C66/5326—Joining single elements to the wall of tubular articles, hollow articles or bars said single elements being substantially flat
    • B29C66/53261—Enclosing tubular articles between substantially flat elements
    • B29C66/53262—Enclosing spouts between the walls of bags, e.g. of medical bags
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/72—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the structure of the material of the parts to be joined
    • B29C66/723—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the structure of the material of the parts to be joined being multi-layered
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/36—Layered products comprising a layer of synthetic resin comprising polyesters
    • B32B27/365—Layered products comprising a layer of synthetic resin comprising polyesters comprising polycarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/08—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using ultrasonic vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/14—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation
    • B29C65/1403—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation characterised by the type of electromagnetic or particle radiation
    • B29C65/1425—Microwave radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B29C65/4805—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the type of adhesives
    • B29C65/483—Reactive adhesives, e.g. chemically curing adhesives
    • B29C65/4845—Radiation curing adhesives, e.g. UV light curing adhesives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B29C65/50—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding using adhesive tape, e.g. thermoplastic tape; using threads or the like
    • B29C65/5007—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding using adhesive tape, e.g. thermoplastic tape; using threads or the like characterised by the structure of said adhesive tape, threads or the like
    • B29C65/5021—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding using adhesive tape, e.g. thermoplastic tape; using threads or the like characterised by the structure of said adhesive tape, threads or the like being multi-layered
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/72—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the structure of the material of the parts to be joined
    • B29C66/723—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the structure of the material of the parts to be joined being multi-layered
    • B29C66/7234—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the structure of the material of the parts to be joined being multi-layered comprising a barrier layer
    • B29C66/72341—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the structure of the material of the parts to be joined being multi-layered comprising a barrier layer for gases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2009/00—Layered products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7148—Blood bags, medical bags
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2439/00—Containers; Receptacles
    • B32B2439/40—Closed containers
    • B32B2439/46—Bags

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Electromagnetism (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Laminated Bodies (AREA)
  • Bag Frames (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Connector Housings Or Holding Contact Members (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A dispenser unit has a flexible polymer bag, a joining part (10, 11) and a stiff hard part (20). The joining part has an inner layer (11) welded to the hard part and an outer polymer layer (10) welded to the inner material of the flexible bag. The inner material (30) of the flexible bag and the outer material of the joining part (10) are the same and are joined in such a way that they may be thermally sterilised. A process for manufacturing this dispenser unit has a step of coextrusion of the multilayered bag material, a step of coextrusion of the multilayered joining part, and steps for sealing the bag material, sealing the multilayered joining part and sealing the hard part. Also disclosed is the use of this dispenser unit for dispensing liquids, in particular aqueous liquids for human or animal medicine or in the food industry.

Description

Transport box, its preparation method with and use
The present invention relates to one and have flexible polymer pouches bag, the transport box of a connector and an inflexibility hard component.Wherein, this connector has the outer polymeric layer that an inner lining material with the interpolymer layer of hard component welding and and flexible bag bag welds.And relate to the preparation method and the application thereof of this transport box.
This transport box can be used as storage and carries liquid, and particularly, but the bag of acceptable heating disinfection wraps on the physiology.They are by transparent polymer, as the polyolefine material preparation, and have a hard component at least.Wherein, it and bag construction materials contract can connect by connector with sterilizing.That is to say that being welded to connect between bag bag and hard component is can stand at least 121 ℃ (steam heating) sterilisation temp and no problem.Bag bag should be transparent, thereby ought change by liquid wherein of living in, during as coagulation, muddiness etc., can find immediately.This bag bag for example is used for medical aspect, as the blood bag, and dialysate body and function bag, plasma bags etc.Certainly also can be applicable in other the aqueous solution, as beverage.
In the prior art, the similar flexible container in the use is a lot, and their big portions are by soft pvc system.PVC suits, and it can be well closely links with the Merlon that is generally used for preparing hard component, and can make transparent, flexible thin film.Yet PVC also has many unsatisfactory aspects simultaneously.PVC must contain plasticizer, so that needed physical characteristic such as flexible can be provided.This plasticizer, for example the phthalic acid di-isooctyl has the tendency that is easy to move away from PVC, and migrates in the bag in the residing liquid.Therefore, depend on the patient of dialysis treatment for a long time, when this PVC bag of life-time service, can absorb the plasticizer of gram magnitude.Be murther on the physiology, cause the infringement that patient is continued.Give thus and seeing, when PVC is got rid of as refuse, can form chlorine compound during owing to burning, cause pollution problem environment.Therefore people have attempted to replace PVC with non-halogenated chemical compound.Though still have problem so far.Yet the favourable characteristics of some of PVC are for example having under the high fluid density, have fabulous and the unchallenged weldability and the transparency, and to the steam block of other materials, and reach economic reasonable consumption.
By patent documentation DE 3247294 A1 as can be known, by polyolefin, bag bag as polyethene preparation, with a connector by the flexible pipe class of vinylacetate and poly copolymer, weld mutually with a hard component of for example making, and it is crosslinked by radiation this joint portion to be carried out subsequently by Merlon.Thus, heating disinfection can be stood in the junction between the PE of PE that makes at the bag bag and link.With the vinyl acetate copolymerized polyethylene that closes with the non-crosslinked state under the heating disinfection temperature, begin the fusing.Therefore, necessity carry out crosslinkedization to the whole device of being made up of this material.
Therefore, at first form soldered between connector and polycarbonate components, then Dichlorodiphenyl Acetate vinyl acetate/polyethylene and ethylene copolymers carry out crosslinkedization.Make chemical compound can stand higher heating disinfection temperature, promptly this bag bag can anti-heating disinfection.Yet above-mentioned crosslinking with radiation needs considerable consumption.Because must send into whole transport box in the corresponding radiation source and carry out processed.
In addition, in the prior art, be very limited to being used to prepare bag selection of the material of bag.Because always must adopt a kind of liner material that contains the welding polyolefin of polyolefin of EVA as the bag bag.Otherwise, just can not guarantee on the PC parts, to wrap inboard being connected with bag.
Known similar device by patent documentation DE-A-3 305 365.Wherein, PVC-free, but the bag bag of heating disinfection have by polyamide, be PA 66 mostly, sticker, the skin of formation and an internal layer that constitutes by polyethylene than intermediate density.
It is unimpeachable that this bag wraps on the physiology, because this polyethylene does not contain plasticizer, it is worth with PVC bag Bao Shi etc. at least, but its cost is very expensive, and used MD polyethylene (than the polyethylene of intermediate density) also is expensive.
Patent documentation EP 380270 has described a kind of patient's of connection flexible pipe material, or introduces the additional material in the flexible bag bag, can also weld mutually with the hard component of Merlon in case of necessity, and knownly can be used as trilaminar hose material.By ultrasound wave, microwave or heat effect its outside can be welded with Merlon.
But the flexible pipe of this heating disinfection shows to have, polypropylene, ethylene/propene copolymer, or the skin of the ethylene/propene copolymer of thermoplastic and high-elastic modification, what it can be with Merlon soldering and sealing.Can make the link resilient intermediate layer that becomes can be very low-density polypropylene, ethylene/vinyl base acetate copolymer, ethylene/methyl acrylate copolymer modification or unmodified, polyvinylidene chloride, the vinylacetic acid ethyl ester, and the ethylene/methyl acrylate copolymer of modification, the mixture of the vinylacetic acid ethyl ester of vinylacetic acid ethyl ester and very low-density polyethylene or modification, its internal layer is a kind of polymer material with high as far as possible heat resistance, for example copolyesters, polypropylene, ethylene/propene copolymer, polyurethane, the mixture of PVC or a kind of copolyesters and vinylacetic acid ethyl ester.
Be used for the flexible pipe material and preferably adopt a kind of material, it is when coextrusion, and the crosslinked action of the cross-linking agent by chemistry or later crosslinking with radiation effect can improve the heatproof degree (but heating disinfection performance) that is welded to connect.Otherwise this material can not keep its characteristic and melt under the heating disinfection condition.This known connector is to prepare in order to be connected with the outside of Merlon, and has complicated structure, and it is connected with flexible bag bag.Do not relate to connector here, and relate to a flexible pipe that is used for liquid that is connected on the polycarbonate components, and must have certainly and can press heat sterilization.
Patent documentation EP-A-564231 has proposed a kind of coextrusion link, is used for being connected of flexible bag bag and Merlon hardware.The polymer material of considering the polyene type is as skin, and its melt flow index is about 12.
Internal layer is on the intermediate layer, and it is flexible that it has link, and SBS for example.Its links and reinforces as containing the articulamentum of vinylacetic acid ethyl ester on Merlon and constitute.This device need carry out the crosslinked usefulness that turns into common measure to the bag bag after link is welded.For example by radiation, but so that said apparatus becomes heating disinfection.
Patent documentation DE 4472175 (COSTER) has described a flexible bag bag with plural layers, show to have improvable mechanical load performance by polyamide or polyester as skin, this bag bag also has an internal layer of being made up of polyethylene or polypropylene, and weld mutually with a connection tube, it has the skin that is made of polyethylene, polypropylene or analog.Because polyethylene and polypropylene are easy to itself or weld well each other.Propose with polyacetals as hard component, and the inner welded that makes link in the above.
Yet also there is defective in said apparatus.Be that it does not possess heating disinfection.
Patent documentation WO/93/23108 (BAXTER) relates to a connector that is used to have the flexible bag bag of PVC.Wherein carry out three layers of extruding, and with the mixture of polypropylene copolymer/styrene/ethylene-butylene-styrene copolymer as skin, and make internal layer by PVC.For the above reasons, it is undesirable using PVC.
In contrast, on this problem, the present invention is that the multiwalled bag bag with polyolefin internal layer is connected with a hard component.Wherein, but bag bag heating disinfection, and its preparation process also is extremely to simplify.
Solve above-mentioned task by the characteristic in the claim 1 of this paper.
In addition, the present invention also relates to the preparation method according to the transport box of aforesaid right requirement, it may further comprise the steps:
Coextrusion multiwalled bag bag material;
Coextrusion multiwalled link;
Sealing bag bag material;
Weld multiwalled link;
The welding hard component.
The present invention also relates to the application by the transport box one of in the aforementioned claim, it is as liquid, especially for the medicine of human body and animal or the liquid, aqueous transport box of food.
To this, advantageously this coextrusion link shows the internal layer of being made up of the polyethylene of high-load EVA by, and carries out crosslinking with radiation separately before sealing.
Further provided advantage of the present invention by following description.
Above-mentioned hard component is by polymer, as Merlon, polyacetals or to also have polyethylene to form be rational.
Thereby, now can be only the internal layer of connector be fixed on the hardware, wherein when frequent employed Merlon, will connect the alkene major part accordingly and carry out crosslinked action, particularly crosslinking with radiation turns usefulness into.Only make link itself carry out expensive cross-linking process.And bag bag itself can have the polyolefin prepared of high thermal stability by inexpensive.
For this reason, also can be the no longer necessary bag bag that be furnished with link, the polyethylene of wherein using high-load EVA carries out radiation treatment by conveyer line, carriage etc., and just link is carried out above-mentioned processing as bag bag internal layer and as the skin of link.Will reduce manufacturing cost like this and reduce environmental pollution.
When with multi-layer flexible pipe of the present invention as link, just can wrap material as bag with good polypropylene, its person's character has high fusing point (140-160 ℃).Therefore, obviously can be used in the higher heating disinfection temperature.Particularly can without a doubt the bag bag be stood steam heating disinfection process.And, can shorten the heating disinfection process again simultaneously.
Shown in patent documentation DE-A-19640038.4, this multilamellar bag bag is preferably made by polypropylene, and its reason just needn't repeat fully.
By steam heating disinfection process, its internal layer surface can not pasted mutually.Thereby it can guarantee to stand the heating disinfection process.
For in the stickup of avoiding taking place its inner surface with PVC or polyethylene during as bag bag internal layer, must make the polyethylene that still uses so far or the surface roughening of PVC.Solution according to the present invention is to adopt dystectic plastics, and must not be connected with Merlon.Thereby avoided the procedure of processing of above-mentioned surface roughening, and this bag bag still also is transparent.
As required, can wrap at bag and be incorporated into a kind of additional barrier layer in the thin film, available ethylene-vinyl alcohol (EVOH) is as the barrier layer, and it is to oxygen, nitrogen CO 2Or other gases seal well.
In addition, can also pass through thin-film technique, apply the other SiO that has xOr the rete of aluminium oxide (for example polyethylene).As shown in the prior art, it can certainly use the made bag bag of laminated film of polyamide/polyethylene.So far, can certainly select the connector with other combinations of substances, so also can avoid whole bag bag is carried out crosslinking with radiation according to the present invention.
Suitable PVC, polyethylene, polypropylene, polyamide and the chemical compound thereof of using of flexible bag bag, have thermoplastic elastomer especially, for example SEBS chemical compound or the multi-layer compound film be made up of itself are as polyethylene/vinyl base ethyl acetate, the PA/ polyethylene, what polypropylene/SEBS etc. formed.When the bag bag is during by coextrusion making, the preparation method that then can adopt all those skilled in the art to use always is carried out.
But above-mentioned connector preferably has a kind of internal layer that chemical compound constituted with a kind of heating disinfection of Merlon, the polyethylene that for example has crosslinkedization of high-load vinylacetic acid ethyl ester, perhaps also can be PVC, as internal layer it in fact not be contained in bag bag in material or liquid phase contact, therefore, in this case, it just is used as the connection material, is can be not problematic.
Can following manufacturing according to transport box of the present invention: press known method, make disinfectant polymer pouches bag, for example with coextrusion method prepare multiwalled bag bag or other similarly bag wrap.In addition, also can be by coextrusion method, prepare independently the flexible pipe form, the multiple layer polymer connector.Its outer material can weld mutually with the internal layer material of bag bag, and its internal layer can weld mutually with the outer material of hard component.Wherein, can make this connector carry out crosslinking with radiation in case of necessity, so that make it can tolerate heating disinfection.In addition, can make hard component with the welding material of a kind of above-mentioned connector internal layer material.Then, hard component is welded mutually with connector, and this connector welds mutually with bag bag internal layer, is welded to connect to form one.So that can stand high-temperature, for example common heating disinfection temperature.
Above-mentioned this transport box is specially adapted to store medical use liquid, dialysis liquid for example, artificial nutritional solution, blood, blood plasma etc.
Therefore, use the compositions of bag of the present invention bag, connector and hard component, at the transport box of the anti-heating disinfection that has hard component in particular cases, can avoid whole bag bag is carried out expensive crosslinking with radiationization.In order to make the used polyolefin that is connected on the hard component can resist the heating disinfection temperature, can only carry out crosslinkedization to link.Because have only it to have high-load vinylacetic acid polyethylene layer ethyl ester, crosslinkedization, it needs again to be connected on the Merlon reliably.
In addition, also can avoid using laminated film bag bag with special, expensive poly polyamide/polyethylene thin film of MD-.It can stand the heating disinfection temperature up to 121 ℃, and according to the present invention, the polyolefin that can use simpler, more cheap also anti-heating is as the skin of connector and the internal layer of bag bag.
The flexible bag bag preferably by PVC, polyethylene, polypropylene, polyamide and thus chemical compound or its multiwalled laminated film, for example form by polyethylene/vinyl base ethyl acetate, polyamide/polyethylene.
For the multiple layer polymer pipe of connector, its skin can be by polyethylene, and PVC constitutes.Wherein, this multiple layer polymer pipe and the mutual sealing of flexible bag bag.
With following accompanying drawing the present invention is described in further detail.But it does not limit the present invention.
Fig. 1. the longitudinal plane view of the connecting portion of connector, hard component and bag bag,
Fig. 2. the cross-sectional view strength of the connecting portion of Fig. 1,
Fig. 3. by bag complete diagram of wrapping of the present invention's preparation.
As seen from Figure 1, in the preferred embodiment of transport box of the present invention, one by the plural layers structure The bag bag that becomes, but be sealing as internal layer, and under the heating disinfection temperature, form weld seam poly-of sealing Alkene, such as polypropylene or polyethylene, polyacrylate compound, etc.
Attaching parts are made of the polymer flexible pipe of bilayer, and its outer material 10 is a kind of can bags with bag Internal layer material 30 welding polyolefin, such as polypropylene or polyethylene, polyacrylate compound, etc. And weld mutually with the internal layer 30 of bag coating.
The internal layer 11 of connector is the polyethylene and ethylene copolymers with the combination of high-load vinylacetic acid ethyl ester. Behind crosslinking with radiation, can weld mutually with Merlon hard component 20. And form anti-heating disinfection, The weld seam of hydraulic seal. And behind heating disinfection, still keep its elasticity and flexible.
In the connector of crosslinking with radiation, welding Merlon pipe.
Embodiment 1
The double-deck flexible pipe that with diameter is 8mm is with the coextrusion link of making of known method.Its skin is thick by 0.45mm, make with the polyethylene of CRATON combination; Its internal layer is thick by 0.5mm, and the polyethylene of high-load vinylacetic acid ethyl ester is made.This flexible pipe material crosslinking with radiationization.Make its internal layer material can obtain about heatproof degree more than 160 ℃.
The bag bag of coextrusion bilayer, its ectomesoderm is made up of polypropylene, and use the polypropylene of the thermoplastic and high-elastic combination identical to form internal layer with the outer material of link, and then the bag bag is passed through high-frequency welding, connect with high-frequency welding with the flexible pipe that is connected of crosslinkedization.Then, the Merlon hard component with pipe fitting is inserted in the connector, then, welds together with it with known method.For this reason, this high-load vinylacetic acid polyethylene ethyl ester, crosslinked has constituted a sealing, and can keep persistent potted line under the heating condition of steam heating disinfection.
Embodiment 2
External diameter is the double-deck flexible pipe of 6mm, and its skin is the thick polyethylene of about 0.5mm, and its internal layer is made up of the polyethylene of the thick high-load vinylacetic acid ethyl ester of about 0.5mm, carries out coextrusion with known method.Then this flexible pipe material carry out crosslinking with radiationization.Make its internal layer material can obtain about heatproof degree more than 160 ℃.
The coextrusion double-ply bag bag of making, wherein its skin is to be made by polyethylene, and make its internal layer with the polyethylene of elastomer combination, carry out the high-frequency welding connection by high-frequency welding with the flexible pipe that is connected of crosslinkedization, wherein the latter's skin is to be made by the polyethylene of combination, its internal layer is then by crosslinkedization, and the polypropylene of high-load vinylacetic acid ethyl ester constitutes.Then, the Merlon hard component is inserted in this link with known method, and sealing it.
Embodiment 3
With external diameter is 8mm, and internal diameter is the flexible pipe of the bilayer of 6mm, and its skin is the thick vinylacetic acid ethyl ester/polypropylene of 0.45mm, and the polyethylene of the internal layer high-load vinylacetic acid ethyl ester that to be 0.5mm thick is coextrusion with known method.Then this flexible pipe material is carried out crosslinking with radiation.Make its internal layer material can obtain about heatproof degree more than 160 ℃.
In water-bath, use the coextrusion three layers of bag bag that are crushed to, wherein, skin is the thick polypropylene of 200 μ, the intermediate layer is that 200 μ are thick, with thermoplastic and high-elastic (CAWITON, by Dutch Wittenburg/Bissum is company preparation) polypropylene of combination, internal layer is that 250 μ are thick, polypropylene with high-load thermoplastic and high-elastic (CAWITON) combination, connect with the flexible pipe high frequency that is connected of crosslinkedization by high-frequency welding, the skin of this flexible pipe be by with the polypropylene of thermoplastic and high-elastic (CAWITON) combination, its internal layer then is crosslinkedization, the polyethylene of high-load vinylacetic acid ethyl ester.Then, the Merlon hard component is inserted with known method, and welding.In bag, can for example be used to store up solution (CAPD) to for example dialysis solution, steam heating disinfection and storage into successive outpatient service peritoneal dialysis.
Though the present invention is described according to preferred embodiment, they do not limit the present invention.For a person skilled in the art, many other schemes all will fall within the scope of protection of the present invention.

Claims (8)

1. has flexomer bag bag, the transport box of link (10,11) and inflexibility hard component (20), wherein this connector has an internal layer that welds mutually with hard component (11), and polymeric outer layer (10) that welds mutually with the internal layer material of this flexible bag bag, it is characterized in that, the internal layer material (30) of this flexible bag bag is identical material with the outer material (10) of link, but and is that heating disinfection ground connects.
2. according to the transport box of claim 1, it is characterized in that this hard component (20) is by polymer, make that wherein the internal layer material of link has a sterilizable weld seam when producing, and is welding as Merlon or polyethylene.
3. according to the transport box one of in the aforementioned claim, it is characterized in that, this flexible bag bag be by PVC and/or by polyethylene, polypropylene, polyamide and with the compositions of thermoplastic and high-elastic, the thin film of SEBS chemical compound or particularly by its multi-layer compound film of making (30,31) as PE/EVA, PA/PE, PP/SEBS waits and makes.
4. according to the transport box one of in the aforementioned claim, it is characterized in that this link is one and hard component, as Merlon or polyethylene, but the internal layer that a kind of chemical compound of heating disinfection constitutes, it is by high-load EVA, and crosslinked polyethylene or PVC make.
5. according to the transport box one of in the aforementioned claim, it is characterized in that, the skin of this bag bag material is made by polypropylene, internal layer is to be made by the polypropylene of combination, and the skin of connector is to be made by the polypropylene of combination, its internal layer is by high-load EVA, and the polyethylene or the PVC of crosslinking with radiationization make, and they weld mutually with a Merlon hard component.
6. according to the preparation method of the transport box one of in the aforementioned claim, it is characterized in that,
Coextrusion multiwalled bag bag material;
Coextrusion multiwalled connector;
Sealing bag bag material;
The multiwalled connector of sealing;
The sealing hard component.
7. according to the method for claim 6, it is characterized in that this coextrusion connector of making is that a polyethylene by high-load EVA is made internal layer, and before sealing, carry out crosslinking with radiationization separately.
8. according to the purposes of the transport box one of in the aforementioned claim, it can be used as liquid, especially for the medicine of human body or animal or the liquid, aqueous transport box of food.
CN97194437A 1996-05-08 1997-04-25 Dispenser unit, process for manufacturing same and its use Pending CN1217648A (en)

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DE29608344U DE29608344U1 (en) 1996-05-08 1996-05-08 Dispensing unit with a flexible polymer bag, a connector and an inflexible hard part

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Publication number Priority date Publication date Assignee Title
CN102555296A (en) * 2010-12-10 2012-07-11 泰尔茂株式会社 Manufacturing Method Of Medical Bag And Medical Bag Thereof
CN105500675A (en) * 2014-09-24 2016-04-20 江西科伦药业有限公司 Transfusion bag and production method thereof
CN109833205A (en) * 2017-11-24 2019-06-04 马文娅 One kind is heatable to hang water bottle

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JP4060222B2 (en) * 2003-03-26 2008-03-12 株式会社大塚製薬工場 Chemical container
DE10342728B3 (en) * 2003-09-16 2005-08-18 Raumedic Ag Filling tube, useful for filling medical products, e.g. blood into bags, comprises outer layer of polypropylene and inner layer of silane-crosslinked ethylene copolymer

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US4417753A (en) * 1981-05-21 1983-11-29 Baxter Travenol Laboratories, Inc. Method and apparatus for joining materials
DE3200264C2 (en) * 1982-01-07 1984-10-31 Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg Medical storage pouch
CA1333165C (en) * 1986-02-07 1994-11-22 Baxter Travenol Laboratories, Inc. Sterilizable multi-layer plastic materials for medical containers and the like

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102555296A (en) * 2010-12-10 2012-07-11 泰尔茂株式会社 Manufacturing Method Of Medical Bag And Medical Bag Thereof
CN102555296B (en) * 2010-12-10 2017-09-01 泰尔茂株式会社 The manufacture method and medical bag of medical bag
CN105500675A (en) * 2014-09-24 2016-04-20 江西科伦药业有限公司 Transfusion bag and production method thereof
CN109833205A (en) * 2017-11-24 2019-06-04 马文娅 One kind is heatable to hang water bottle

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HUP9901428A2 (en) 1999-08-30
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DE29608344U1 (en) 1997-09-04
BR9709218A (en) 2000-12-12

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