CN120160880A - A blood testing device for experimental animals - Google Patents
A blood testing device for experimental animals Download PDFInfo
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- CN120160880A CN120160880A CN202510330102.8A CN202510330102A CN120160880A CN 120160880 A CN120160880 A CN 120160880A CN 202510330102 A CN202510330102 A CN 202510330102A CN 120160880 A CN120160880 A CN 120160880A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D19/00—Degasification of liquids
- B01D19/0073—Degasification of liquids by a method not covered by groups B01D19/0005 - B01D19/0042
- B01D19/0078—Degasification of liquids by a method not covered by groups B01D19/0005 - B01D19/0042 by vibration
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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Abstract
The invention belongs to the technical field of blood detection, in particular to a blood detection device for experimental animals, which comprises a detector body, a sample injection needle, a sample mixing part, a clamping assembly, a driving assembly and a telescopic structure, wherein the sample mixing part comprises a disc rotatably arranged on the detector body, a plurality of fixing seats arranged on the disc, the clamping assembly is rotatably arranged on the fixing seats, the driving assembly is arranged on the fixing seats and comprises a main shaft rotatably arranged on the fixing seats and a secondary shaft for driving clamping jaws to rotate, the secondary shaft and the main shaft are respectively provided with a plurality of groups of secondary gears and a main gear, the gear ratio of each group of secondary gears and the main gear is different, the secondary shaft adopts a telescopic structure, and the driving assembly is arranged to realize that blood sampling tubes with different specifications adopt different shaking speeds, so that blood and an anticoagulant are uniformly mixed, hemolysis or uneven mixing condition is avoided, and the accuracy and the efficiency of detection are improved.
Description
Technical Field
The invention belongs to the field of blood detection, and particularly relates to a blood detection device for experimental animals.
Background
In order to obtain new knowledge about biology, medicine, etc., scientific research is performed by performing experiments on animals, and in the experiments, in order to evaluate health conditions of animals, diagnose diseases, monitor therapeutic effects, study physiological functions, etc., a blood detection device is required to detect blood of experimental animals so as to obtain detailed information about blood components such as red blood cells, white blood cells, platelets, etc., thereby accurately judging physical conditions of the experimental animals and providing reliable data support for subsequent researches.
One patent application with publication number of CN117589977A discloses a blood vortex oscillation auxiliary detection device for detecting animal epidemic disease, which comprises a shell, a fixed disk, a driving motor arranged on the fixed disk, a vertical rod arranged on the fixed disk, bevel gears arranged on the vertical rod and the driving motor, a disc and a placing groove arranged on the vertical rod, a clamping assembly arranged in the placing groove, a blood collection tube arranged in the placing groove, an oscillator for mixing blood and an anticoagulant in the blood collection tube after clamping the blood collection tube, and the blood can be detected after mixing for a period of time.
After the blood of experimental animals is sampled, need rock the heparin tube before detecting to mix blood and anticoagulant in the heparin tube, in order to avoid the problem of blood coagulation when detecting, above-mentioned device can only mix blood sample and anticoagulant of same specification, can not adapt to the demand of different specification samples, however animal experiments can generally adopt different varieties of animals, the different animal is its blood sampling volume is different, the specification of heparin tube that consequently adopts is different, lead to the unable nimble many specification demands of coping of current device, the heparin tube of different specifications adopts same shake speed, can produce and shake the too big and hemolysis of speed or shake the too little and uneven problem of mixing of speed.
To this end, the present invention provides a blood test apparatus for laboratory animals.
Disclosure of Invention
In order to make up the defects of the prior art, the problem that the prior device provided in the background art cannot flexibly cope with the requirements of multiple specifications is solved.
The technical scheme includes that the experimental animal blood detection device comprises a detector body, a sample injection needle, a sample mixing part for mixing animal blood and anticoagulant, a plurality of fixing seats mounted on the disc in a rotating mode, clamping assemblies mounted on the fixing seats in a rotating mode, and a driving assembly mounted on the fixing seats, wherein the driving assembly comprises a main shaft rotatably mounted on the fixing seats and a secondary shaft for driving clamping jaws to rotate, the secondary shaft and the main shaft are respectively provided with a plurality of groups of secondary gears and main gears, the gear ratios of each group of secondary gears and the main gear are different, the secondary shaft adopts a telescopic structure, the secondary gears and the main gears of different groups are meshed under the condition that the rotation speed of the main shaft is unchanged, and the rotation speeds of the secondary shafts are different.
Preferably, the driving assembly further comprises a handle rotatably mounted on the fixing seat, the handle is fixedly mounted on the clamping assembly, a first rotary ring rotatably mounted on the fixing seat, a long rod slidably mounted on the fixing seat and in threaded connection with the first rotary ring, the clamping assembly comprises clamping jaws, the long rod penetrates through the handle and is in rotary connection with the clamping jaws of the clamping assembly, a second rotary ring rotatably mounted on the fixing seat, a belt for transmission is mounted between the first rotary ring and the second rotary ring, a pull rod in threaded connection with the second rotary ring, a circular ring rotatably mounted on the auxiliary shaft and located at the movable end of the auxiliary shaft, and a connecting rod is rotatably connected between the circular ring and the pull rod.
Preferably, the driving assembly further comprises a first gear fixedly arranged on the handle, a mounting plate slidingly arranged on the fixing seat, a plurality of rack plates arranged on the mounting plate and used for driving the first gear to rotate, part of the rack plates are slidingly connected with the mounting plate, a plurality of switches arranged in the handle, different switches are used for controlling the different rack plates to slide, and the long rod comprises a protruding part used for triggering the switches.
The driving assembly comprises a fixed seat, a sliding plate, a groove, two inserting rods, a screw rod, a cam, a first ratchet wheel, a first spring and a first pawl, wherein the sliding plate is arranged on the fixed seat in a sliding mode, the groove is formed in the mounting plate, the mounting plate and the rack plate are symmetrically distributed on two sides of the first gear, the inserting rods are arranged on the sliding plate in a sliding mode and matched with the groove in use, the screw rod is arranged on the fixed seat in a rotating mode and used for driving the sliding plate to slide up and down, a chain belt is arranged between the screw rod and the auxiliary shaft and is used for driving the sliding plate in a driving mode, the cam and the first ratchet wheel are arranged on the sliding plate in a rotating mode and are fixedly connected, the cam is used for pushing the inserting rods to slide relative to the sliding plate, the first spring is arranged between the inserting rods and the sliding plate, the first pawl is used for driving the first ratchet wheel to rotate, the first pawl is arranged on the fixed seat in a moving range of the first pawl.
Preferably, the sample mixing part further comprises a monitoring assembly arranged on the detector body, wherein the monitoring assembly is used for observing whether hemolysis occurs in blood in the blood collection tube.
The sample mixing part comprises a fixed seat, a third rotating ring, a knocking rod, a gear plate, a gear set and a gear set, wherein the fixed seat is arranged on the detector body, the third rotating ring is arranged on the fixed seat in a rotating mode, the knocking rod is arranged on the fixed seat in a sliding mode, a sliding groove is formed in the knocking rod, a protrusion is arranged on the third rotating ring, a second spring is arranged between the third rotating ring and the knocking rod, the third rotating ring drives the knocking rod to vertically reciprocate in a knocking mode through the double functions of the protrusion and the second spring, the gear plate is arranged on the detector body in a sliding mode, the gear set is used for driving the third rotating ring to rotate, and the gear set is arranged on the fixed seat in a rotating mode.
The sample mixing part comprises a fixing seat, a round rod, two gears, a third gear, a third telescopic rod, a second ratchet, a third spring, a fourth gear and a second pawl, wherein the round rod is arranged on the fixing seat, the third gear is rotatably arranged on the round rod, the third gear is unidirectionally driven between the two gears, one of the third gears is meshed with the third rotary ring, the second ratchet is rotatably arranged on the fixing seat and is meshed with the third gear, the second ratchet is provided with a bump, the third ratchet is rotatably arranged on the fixing seat, an inductor is fixedly arranged on the third ratchet and is matched with the bump, the second pawl is slidably arranged on the fixing seat and is used for limiting the third ratchet and the second ratchet to unidirectionally rotate, the third telescopic rod is fixedly arranged on the fixing seat and is used for driving the second pawl to slide, the third ratchet is arranged on the third ratchet and the third spring is arranged on the fixing seat, the fourth gear is rotatably arranged on the fixing seat and is used for driving the third ratchet.
The beneficial effects of the invention are as follows:
1. According to the blood detection device for the experimental animal, provided by the invention, the driving assembly is arranged to realize that blood collection tubes with different specifications adopt different shaking speeds and shaking turns, so that the blood and the anticoagulant are ensured to be uniformly mixed, the conditions of hemolysis or uneven mixing are avoided, and the detection accuracy and efficiency are improved.
2. According to the blood detection device for the experimental animal, the inserted link and the groove are arranged, so that the sampling tube can be rotated and mixed in different directions, and the sufficient mixing of liquid in the blood sampling tube is further ensured.
3. According to the blood detection device for the experimental animal, the knocking rod is arranged, after the monitoring component detects that the blood collection tube contains the bubbles, the blood collection tube is knocked, and the bubbles rise to the top end of the blood collection tube through knocking, so that the bubbles are eliminated, the blood sample in the blood collection tube is sufficient and free of bubble interference, and the purity and the detection accuracy of the sample are maintained.
4. According to the blood detection device for the experimental animal, provided by the invention, the frequency generated by the hemolysis and the bubble phenomenon on the fixing seat in a period of time is detected by arranging the sensor and the convex blocks, so that the problems of the generation of the hemolysis and the bubble phenomenon in the blood sampling tube and the influence on the detection result caused by the damage of components on the fixing seat are avoided.
Drawings
The invention is further described below with reference to the accompanying drawings.
FIG. 1 is a perspective view of a first embodiment of the present invention;
FIG. 2 is a schematic illustration of the location of a monitoring assembly of the present invention;
FIG. 3 is a schematic view of the structure of the holder and the clamping jaw of the present invention;
FIG. 4 is a cross-sectional view of a holder of the present invention;
FIG. 5 is a schematic illustration of the location of the grooves of the present invention;
FIG. 6 is a schematic view of the position of the first ratchet wheel of the present invention;
FIG. 7 is a schematic view of the structure of the cam of the present invention;
FIG. 8 is a cross-sectional view of a handle of the present invention;
FIG. 9 is a schematic view of the structure of the tapping rod and the third ring according to the present invention;
FIG. 10 is a schematic representation of the structure of the third gear and gear set of the present invention;
The sample holder comprises a detector body, a sample injection needle, a sample mixing part, 31, a disc, 32, a fixed seat, 33, a driving component, 331, a main shaft, 332, a secondary shaft, 333, a secondary gear, 334, a main gear, 335, a handle, 336, a first rotary ring, 337, a long rod, 338, a second rotary ring, 339, a pull rod, 3310, a circular ring, 3311, a connecting rod, 3312, a first gear, 3313, a mounting plate, 3314, a rack plate, 3315, a switch, 3316, a slide plate, 3317, a groove, 3318, an inserting rod, 3319, a lead screw, 3320, a cam, 3321, a first ratchet wheel, 3322, a first spring, 3323, a first pawl, 34, a monitoring component, 35, a third rotary ring, 36, a knocking rod, 37, a second spring, 38, a tooth plate, 39, a gear set, 310, a circular rod, 311, a third gear, 312, a second ratchet wheel, 313, a bump, a third ratchet wheel, 315, an inductor, a second pawl, 317, a third pawl, a 33, a fourth spring, a fourth pawl, a 33, a fourth spring, a telescopic component and 41.
Detailed Description
The invention is further described in connection with the following detailed description in order to make the technical means, the creation characteristics, the achievement of the purpose and the effect of the invention easy to understand.
As shown in fig. 1 to 10, the blood test apparatus for an experimental animal according to the embodiment of the present invention comprises a detector body 1 and a sample injection needle 2, and further comprises a sample mixing part 3 for mixing blood of the animal and an anticoagulant, wherein the sample mixing part 3 comprises a disk 31 rotatably mounted on the detector body 1, a plurality of holders 32 rotatably mounted on the disk 31, a clamping assembly 4 rotatably mounted on the holders 32, and a driving assembly mounted on the holders 32, the driving assembly comprises a main shaft 331 rotatably mounted on the holders 32 and a sub shaft 332 for driving the clamping jaw 41 to rotate, a plurality of sets of sub gears 333 and main gears 334 are respectively mounted on the sub shaft 332 and the main shaft 331, the sub shaft 332 adopts a telescopic structure, and the sub gears 333 and the main gears 334 of different sets are engaged under the condition that the rotation speed of the main shaft 331 is unchanged.
Specifically, after the experimental animal is sampled, before the experimental animal is detected, the blood sampling tube needs to be rocked so as to mix the blood in the blood sampling tube with the anticoagulant, so that the problem of blood coagulation is avoided in detection, the existing device can only mix the blood sample with the same specification with the anticoagulant and cannot adapt to the requirements of samples with different specifications, however, animal experiments usually adopt different varieties of animals, the blood sampling amounts of the different animals are different, the adopted blood sampling tubes have different specifications, the existing device cannot flexibly cope with the requirements of multiple specifications, and the blood sampling tubes with different specifications adopt the same rocking speed, so that the problems of overlarge rocking speed, hemolysis or uneven mixing due to overlarge rocking speed can be generated;
The detector body 1 and the sampling needle 2 can adopt the existing blood detecting instrument such as blood routine, and the like, in an initial state, the lowest auxiliary gear 333 is meshed with the main gear 334, after blood collection, a blood collection tube is placed in the clamping jaw 41, the blood collection tube is clamped by the clamping jaw 41, then according to different blood collection tube specifications, the auxiliary shaft 332 is controlled to stretch so as to enable the auxiliary gear 333 of the corresponding group to be meshed with the main gear 334, the rotation speed of the main shaft 331 is the same, the rotation speed of the auxiliary shaft 332 is different under the condition that the tooth ratio of the auxiliary gear 333 to the main gear 334 is different, so that the rotation speed of the clamping jaw 41 is different, the accurate mixing of blood and anticoagulant in different specifications of the blood collection tube is realized, the rotation of the disc 31 is controlled, when the disc 31 rotates to the lower side of the sampling needle 2, the sample collection of the blood collection tube is controlled by the sampling needle 2, the detection of the detector body 1 is controlled to continue rotating so as to carry out the sampling and detection on the next blood collection tube of different specifications, namely the continuous mixing and detection actions of the blood collection tubes of different specifications are realized;
Through setting up drive assembly 33 to realize that the heparin tube of different specifications adopts different rocking speeds, ensure blood and anticoagulant homogeneous mixing, avoid hemolysis or the inhomogeneous condition of mixing, improved accuracy and the efficiency of detection.
As shown in fig. 4 and 8, the driving assembly 33 further includes a handle 335 rotatably mounted on the fixing base 32, the handle 335 being fixedly mounted on the clamping assembly 4, a first swivel 336 rotatably mounted on the fixing base 32, a long rod 337 slidably mounted on the fixing base 32, the long rod 337 being screwed with the first swivel 336, the clamping assembly 4 including a clamping jaw 41, the long rod 337 being rotatably connected with the clamping jaw 41 of the clamping assembly 4 through the handle 335, a second swivel 338 rotatably mounted on the fixing base 32, a belt for transmission being mounted between the first swivel 336 and the second swivel 338, a pull rod 339 screwed on the second swivel 338, a ring 3310 rotatably mounted on the auxiliary shaft 332, the ring 3310 being located at a movable end of the auxiliary shaft 332, and a link 3311 being rotatably connected between the ring 3310 and the pull rod 339.
Specifically, when the blood collection tube is clamped by the clamping jaw 41 of the clamping assembly 4, during the process that the clamping jaw 41 is mutually close, the clamping jaw 41 moves to drive the long rod 337 to move synchronously, the long rod 337 is in threaded connection with the first rotary ring 336, so that the first rotary ring 336 rotates, the second rotary ring 338 rotates synchronously, the pull rod 339 moves left and right relative to the auxiliary shaft 332, the pull rod 339 moves to drive the pull rod 339 to rotate, the pull rod 339 rotates to enable the circular ring 3310 to move up and down, the auxiliary shaft 332 contracts upwards due to the fact that the rotating rings move up and down, the distances of the clamping jaw 41 move are different due to the fact that the distances of the auxiliary shaft 332 contracts upwards are different due to the fact that the blood collection tubes with different specifications are different, the rotating speeds of the auxiliary shaft 332 are different, and the rotating speeds of the meshed main gear 334 and auxiliary gear 333 are different.
As shown in fig. 4, 5 and 8, the driving assembly 33 further includes a first gear 3312 fixedly mounted on the handle 335, a mounting plate 3313 slidably mounted on the fixing base 32, a plurality of rack plates 3314 mounted on the mounting plate 3313, a portion of the rack plates 3314 being slidably connected to the mounting plate 3313 for driving the first gear 3312 to rotate, a plurality of switches 3315 mounted in the handle 335, different ones of the switches 3315 being for controlling sliding movement of the different ones of the rack plates 3314, and the long shaft 337 having a protrusion for triggering the switches 3315.
Specifically, the smaller the size of the blood collection tube is, the more switches 3315 triggered by the long rod 337 are, the more different second telescopic rods are controlled to shrink through different switches 3315, the corresponding rack plate 3314 can be pushed to move after the second telescopic rods shrink, so that the corresponding rack plate 3314 is not on the same plane with the first gear 3312, then the mounting plate 3313 is controlled to slide up and down, the mounting plate 3313 slides up and down to drive the rack plate 3314 to synchronously move, the first gear 3312 is driven to reciprocate when the rack plate 3314 moves up and down, the fewer the number of times of reciprocating movements of the mounting plate 3313 are, the fewer the number of times of the rotation of the first gear 3312 is, namely the fewer the number of times of the rotation of the blood collection tube is, so that accurate control of the blood collection tube with different sizes is further realized, the best mixing effect is ensured, and hemolysis or uneven mixing condition is avoided.
As shown in fig. 4 to 8, the driving assembly 33 further includes a slide plate 3316 slidably mounted on the fixed base 32, a recess 3317 formed on the mounting plate 3313, the mounting plate 3313 and the rack plate 3314 having two sets of gears symmetrically distributed on both sides of the first gear 3312, two insert bars 3318 slidably mounted on the slide plate 3316, the insert bars 3318 being engaged with the recess 3317, a lead screw 3319 rotatably mounted on the fixed base 32, the lead screw 3319 for driving the slide plate 3316 to slide up and down, a chain belt mounted between the lead screw 3319 and the auxiliary shaft 332 and driven by the chain belt, a cam 3320 rotatably mounted on the slide plate 3316 and a first ratchet 3321, the cam 3320 being fixedly connected with the first ratchet 3321, the cam 3320 for pushing the insert bars 3318 to slide with respect to the slide plate 3316, a first spring 3322 mounted between the insert bars 3318 and the slide plate 3316, a first pawl 3323 for driving the first ratchet 3321 to rotate, the first ratchet 3323 being rotatably mounted on the fixed base 32, and the first ratchet 3321 being located within a moving range of the first ratchet 3323.
Specifically, the screw rod 3319 adopts a reciprocating screw rod 3319, in an initial state, the insert rod 3318 at one side of the slide plate 3316 is inserted into the groove 3317 of the mounting plate 3313, when the materials are mixed, the main gear 334 rotates to drive the auxiliary gear 333 and the auxiliary shaft 332 to synchronously rotate, the auxiliary shaft 332 drives the screw rod 3319 to rotate through the chain belt, the screw rod 3319 rotates to drive the slide plate 3316 to reciprocate up and down, the slide plate 3316 can drive the mounting plate 3313 and the rack plate 3314 to synchronously move through the insert rod 3318, the first ratchet wheel 3321 is contacted with the first pawl 3323 in the middle of the movement of the slide plate 3316 to the original position, the cam 3320 is driven to synchronously rotate by the push of the first pawl 3323, the insert rod 3318 at the other side is inserted into the groove 3317 of the mounting plate 3313 at the other side, namely, when the slide plate 3316 reciprocates up and down again under the elastic force of the first spring 3322, the insert rod 3318 drives the mounting plate 3313 at the other side to reciprocate up and down through the insert rod 3313 and the rack plate 3314, and the liquid can be fully mixed with the sample tube 3318 in the direction of the reciprocating direction.
As shown in fig. 2, the sample mixing part 3 further includes a monitoring assembly 34 mounted on the detector body 1, and the monitoring assembly 34 is used for observing whether hemolysis occurs in blood in the blood sampling tube.
Specifically, the monitoring component 34 adopts the existing industrial camera and the system thereof, and can judge whether the problem exists or not through shooting comparison, the monitoring component 34 is used for observing the condition of blood in each blood collection tube, and when the hemolysis phenomenon occurs, the monitoring component 34 is used for transmitting image information to an operator in real time so as to find out the problem in time, find out the reason of data abnormality and avoid influencing the experimental result.
As shown in fig. 9 and 10, the sample mixing part 3 further comprises a third rotary ring 35 rotatably mounted on the fixed seat 32, a knocking rod 36 vertically slidably mounted on the fixed seat 32, a chute formed on the knocking rod 36, a protrusion formed on the third rotary ring 35, a second spring 37 arranged between the third rotary ring 35 and the knocking rod 36, the third rotary ring 35 rotating to drive the knocking rod 36 to reciprocally knock up and down through the double action of the protrusion and the second spring 37, a toothed plate 38 vertically slidably mounted on the detector body 1, a gear set 39 for driving the third rotary ring 35 to rotate, and the gear set 39 rotatably mounted on the fixed seat 32.
Specifically, due to the influence of factors such as too high shaking speed, improper blood sampling technology, improper operation mode and the like, after the blood sampling tube is uniformly mixed, bubbles can be generated in the blood sampling tube, the existence of the bubbles can occupy the space in the blood sampling tube, and the problems of insufficient blood sample quantity actually entering an instrument, influence on detection results and the like can be caused;
after detecting that the blood collection tube contains bubbles in the monitoring assembly 34, the tooth plate 38 is controlled to slide downwards, so that when the fixed seat 32 drives the swivel to rotate to the position, the gear set 39 can be driven to rotate, the gear set 39 rotates to drive the third swivel 35 to rotate, the swivel rotates to enable the knocking rod to reciprocate up and down, the blood collection tube is knocked, the bubbles are enabled to rise to the top end of the blood collection tube through knocking, the bubbles are eliminated, sufficient and bubble-free interference of blood samples in the blood collection tube is ensured, and the purity and detection accuracy of the samples are maintained.
As shown in fig. 10, the sample mixing part 3 further comprises a round bar 310 mounted on the fixed base 32, two gears 311 rotatably mounted on the round bar 310, two gears 311 and a unidirectional transmission between the gears 311, wherein one gear 311 is meshed with a third rotating ring 35, a second ratchet 312 rotatably mounted on the fixed base 32, the second ratchet 312 is meshed with the gear 311, a bump 313 is arranged on the second ratchet 312, a third ratchet 314 rotatably mounted on the fixed base 32, an inductor 315 is fixedly mounted on the third ratchet 314, the inductor 315 is matched with the bump 313, a second pawl 316 slidably mounted on the fixed base 32 is used for limiting unidirectional rotation of the third ratchet 314 and the second ratchet 312, a third telescopic rod 317 fixedly mounted on the fixed base 32 is used for driving the second pawl 316 to slide, a third spring 318 mounted on the third ratchet 314 and the fixed base 32, a fourth ratchet 319 rotatably mounted on the fixed base 32 is used for driving the third ratchet 314.
Specifically, the second pawl 316 limits the third ratchet 314 to rotate only counterclockwise, the second ratchet 312 rotates only clockwise, the second pawl 316 is engaged with the second ratchet 312 and the third ratchet 314 in an initial state, when the monitoring assembly 34 observes that the blood in the blood collection tube is hemolyzed, the tooth plate 38 is controlled to move downward to engage with the fourth gear 319, then when the fixing seat 32 rotates along with the blood collection tube and the fourth gear 319, the fourth gear 319 rotates to drive the third ratchet 314 to rotate counterclockwise for a certain angle (taking an example from the top down view in fig. 10), so that the distance between the sensor 315 and the bump 313 is reduced, and the third spring 318 stretches at the moment;
when the monitoring assembly 34 observes that bubbles appear in the blood collection tube, the control tooth plate 38 moves downwards to be meshed with the gear set 39, then when the fixing seat 32 carries the blood collection tube and the gear set 39 to rotate, the gear set 39 rotates to drive the third rotary ring 35 to rotate, the third rotary ring 35 drives the third gear 311 to synchronously rotate, the third gear 311 drives the second ratchet wheel 312 to rotate clockwise for a certain angle, the distance between the sensor 315 and the protruding block 313 is reduced, and the third spring 318 stretches at the moment;
When the three-size telescopic rod 317 intermittently stretches and stretches, the three-size telescopic rod 317 stretches and stretches, so that the second pawl 316 does not contact with the third ratchet 314 and the second ratchet 312 for a while, at this time, the third ratchet 314 and the second ratchet 312 can rotate clockwise and anticlockwise respectively under the action of the elastic force of the third spring 318, and therefore the distance between the inductor 315 and the bump 313 is increased;
If the hemolysis and bubble phenomena occur more on the fixing base 32, the speed of the smaller distance between the sensor 315 and the bump 313 will be greater than the speed of the increase of the distance between the sensor 315 and the bump 313 until the sensor 315 contacts with the bump 313, at this time, the sensor 315 is triggered to transmit a signal to a worker to check whether the component on the fixing base 32 has a problem, so as to avoid too fast shaking speed of the blood collection tube;
If the fixing base 32 has less hemolysis and air bubbles on the fixing base 32, the smaller distance between the sensor 315 and the bump 313 will be smaller than the increasing distance between the sensor 315 and the bump 313, and the sensor 315 is not triggered;
By arranging the sensor 315 and the bump 313, the frequency of the hemolysis and the bubble phenomenon generated on the fixing seat 32 in a period of time is detected, so that the problems of the hemolysis and the bubble phenomenon in the blood sampling tube and the influence on the detection result are avoided due to the damage of components on the fixing seat 32.
The working principle is that in the initial state, the lowest auxiliary gear 333 is meshed with the main gear 334, after blood collection, a blood collection tube is placed in the clamping jaw 41, the blood collection tube is clamped by the clamping jaw 41, when the blood collection tube is clamped by the clamping jaw 41 of the clamping assembly 4, the clamping jaw 41 moves to drive the long rod 337 to synchronously move, the long rod 337 is in threaded connection with the first rotary ring 336, the first rotary ring 336 rotates to drive the second rotary ring 338 to synchronously rotate, the pull rod 339 moves left and right relative to the auxiliary shaft 332, the pull rod 339 moves to drive the pull rod 339 to rotate, the annular ring 3310 moves up and down due to the rotation of the pull rod 339, the auxiliary shaft 332 upwardly contracts due to the upward movement of the rotary ring, the distances of the clamping jaws 41 move are different due to the blood collection tubes of different specifications, the upward contraction distances of the auxiliary shaft 332 are different, the meshed main gear 334 and the auxiliary gear 333 are different, and the rotation speeds of the auxiliary shaft 332 are different;
In the initial state, the insert rod 3318 on one side of the slide plate 3316 is inserted into the groove 3317 of the mounting plate 3313, when mixing, the main gear 334 rotates to drive the auxiliary gear 333 and the auxiliary gear 332 to synchronously rotate, the auxiliary gear 332 drives the screw rod 3319 to rotate through the chain belt, the screw rod 3319 rotates to drive the slide plate 3316 to reciprocate up and down, the slide plate 3316 moves up and down, the insert rod 3318 can drive the mounting plate 3313 and the rack plate 3314 to synchronously move, and the rotation of the first gear 3312, the clamping jaw 41 and the blood collection tube is realized, namely the mixing action of blood and anticoagulant in the blood collection tube is realized;
The smaller the specification of the blood collection tube is, the more switches 3315 triggered by the long rod 337 are, the different second telescopic rods are controlled to shrink through the different switches 3315, the corresponding rack plate 3314 can be pushed to move after the second telescopic rods shrink, so that the corresponding rack plate 3314 is not on the same plane with the first gear 3312, then the mounting plate 3313 is controlled to slide up and down, the mounting plate 3313 slides up and down to drive the rack plate 3314 to synchronously move, the first gear 3312 is driven to reciprocate when the rack plate 3314 moves up and down, and under the condition that the number of times of up and down reciprocation of the mounting plate 3313 is unchanged, the fewer the rack plates 3314 meshed with the first gear 3312 are arranged on the mounting plate 3313, namely the fewer the number of circles of rotation of the first gear 3312 are, namely the number of circles of rotation of the blood collection tube is reduced, so that the accurate control of the blood collection tube with different specifications is further realized;
After the monitoring component 34 detects that the blood collection tube contains bubbles, the tooth plate 38 is controlled to slide downwards, so that when the fixed seat 32 drives the swivel to rotate to the position, the gear set 39 can be driven to rotate, the gear set 39 rotates to drive the third swivel 35 to rotate, the swivel rotates to enable the knocking rod to reciprocate up and down, the blood collection tube is knocked, the bubbles are enabled to rise to the top end of the blood collection tube through knocking, the bubbles are eliminated, sufficient and bubble interference-free blood samples in the blood collection tube are ensured, and purity and detection accuracy of the samples are maintained;
The control disc 31 rotates, when the disc 31 rotates to the position below the sampling needle 2, the mixing is finished, the sampling needle 2 is controlled to sample the blood collection tube, the detector body 1 detects, after the detection is finished, the control disc 31 continues to rotate so as to sample and detect the next blood collection tube, and continuous mixing and detection actions of the blood collection tubes with multiple specifications are realized.
The foregoing has shown and described the basic principles, principal features and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present invention, and various changes and modifications may be made without departing from the spirit and scope of the invention, which is defined in the appended claims. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (7)
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| Application Number | Priority Date | Filing Date | Title |
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| CN202510330102.8A CN120160880A (en) | 2025-03-20 | 2025-03-20 | A blood testing device for experimental animals |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120890954A (en) * | 2025-09-19 | 2025-11-04 | 中国人民解放军总医院第三医学中心 | A device for detecting agglutination in anticoagulated blood samples for hemoglobin analysis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120890954A (en) * | 2025-09-19 | 2025-11-04 | 中国人民解放军总医院第三医学中心 | A device for detecting agglutination in anticoagulated blood samples for hemoglobin analysis |
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