CN120078876A

CN120078876A - A compound medicine for treating burns and scalds and its preparation method

Info

Publication number: CN120078876A
Application number: CN202411393811.2A
Authority: CN
Inventors: 鲁朝兰
Original assignee: Individual
Current assignee: Individual
Priority date: 2024-10-08
Filing date: 2024-10-08
Publication date: 2025-06-03

Abstract

The present application relates to a compound medicine for treating burns and scalds and a preparation method thereof. The compound medicine is prepared from borneol powder, catechu powder, indigo powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil and an organic preservative in a ratio of 2:2:2:2:1.5:1:50:0.25. In a sterile environment, the borneol powder, catechu powder, indigo powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil and an organic preservative are placed in a sterile and water-free container and mixed in proportion for an unlimited time, and the mixture is obtained by fully stirring. Step 2: putting the mixture into a glass bottle and vacuum sealing it for storage. When it is needed later, take it out and use it, and apply it directly to the affected area, which can significantly improve the healing effect of injuries to human skin, muscle tissue, meridians, bones and the like after burns and scalds.

Description

Compound medicament for treating burns and scalds and preparation method thereof

Technical Field

The application belongs to the technical field of burn and scald treatment, and particularly relates to a compound medicament for treating burn and scald and a preparation method thereof.

Background

Burn and scald is a kind of injury of skin, muscle, tendons and bones caused by water, hot oil, steam, flame, hot metal liquid or solid, electricity, chemical substances, radioactive rays or fire arms in war time.

At present, most of western medicines and injections are used for treating burns and scalds, such as analgesic and pain relieving, antibiotic for preventing infection, large side effect, strong resistance, unstable curative effect, difficult healing of wounds and easy muscle loss and depression after healing, traditional Chinese medicine decoction and injection have certain curative effect, but have various toxic and side effects, long treatment period, slow granulation speed, hyperplasia of the healed affected parts and common melanin pigmentation, and the common external ointment for treating burns and scalds can generate slight secondary injury to fragile wounds when in use, and the adhesive force on the surface of the focus is not strong when the preparation is used outside, so that the efficacy of the medicine is greatly reduced.

Disclosure of Invention

The invention aims to solve the technical problems that the side effect of the traditional Chinese medicine and the western medicine and the injection is large, the curative effect is unstable, and the adhesive force on the surface of a focus is not strong when the traditional Chinese medicine decoction and the injection are externally used, so that the efficacy of the medicine is greatly reduced, thereby providing a compound medicine for treating burns and scalds and a preparation method thereof.

The technical scheme adopted for solving the technical problems is as follows:

A compound medicament for treating burns and scalds comprises the following raw materials:

borneol powder used for clearing heat and relieving pain, preventing corrosion, promoting tissue regeneration, inducing resuscitation and refreshing;

catechu powder for cooling blood, dispelling blood stasis, astringing, stopping bleeding, promoting granulation, and resisting ulcer;

medicinal material indigo naturalis powder for clearing heat and detoxicating, promoting blood circulation and removing blood stasis and eliminating spots;

cooling blood, promoting blood circulation, removing toxic substance, promoting eruption and resolving macula;

Calcium carbonate with molecular formula of CaCO ₃ for preventing edema, reducing inflammation, protecting vascular endothelial cells and promoting wound healing;

Egg white protein powder which is beneficial to healing of wounds and incision and can maintain normal functions and metabolism of cells is food grade or fresh egg white is selected;

antioxidant refined rapeseed oil;

An organic preservative, wherein the organic preservative is potassium sorbate;

Specifically, the ratio of borneol powder, catechin powder, natural indigo powder, lithospermum powder, calcium carbonate, egg white protein powder/fresh egg white, refined rapeseed oil and organic preservative is=2:2:2:2:1.5:1:50:0.25.

The Borneolum Syntheticum powder has 800-1000 meshes, and Catechu powder, indigo naturalis powder, radix Arnebiae powder, and ovum gallus Domesticus album protein powder may also have 800-1000 meshes.

The catechu powder, the natural indigo powder and the lithospermum powder are special grade medicinal materials, and the special grade Chinese medicinal materials are the highest grade Chinese medicinal materials, so that the quality is excellent and the medicinal effect is obvious. The raw materials of the traditional Chinese medicinal materials are derived from pure and high-quality production places in the world, and the purity and the integrity of active ingredients of the traditional Chinese medicinal materials are ensured through strict screening and processing processes. Superfine Chinese medicinal materials are commonly used in important Chinese medicinal formulas, and have wide application in the field of pharmacy.

A preparation method of a compound medicament for treating burns and scalds comprises the following steps:

Step 1, under the aseptic environment, putting borneol powder, catechin powder, natural indigo powder, lithospermum powder, calcium carbonate, egg white protein powder/fresh egg white, refined rapeseed oil and an organic preservative into an aseptic anhydrous container for mixing in proportion, wherein the time is not limited, and fully and uniformly stirring to obtain a mixture;

And 2, filling the mixture into a glass bottle, vacuum sealing and preserving, and taking out for use when the mixture is needed to be used later.

The method comprises the steps of (1) immersing dried radix Arnebiae in refined rapeseed oil for more than 48 hours, taking out radix Arnebiae to obtain radix Arnebiae oil, weighing Borneolum Syntheticum powder, catechu powder, indigo naturalis powder, calcium carbonate, egg white protein powder or fresh egg white, and potassium sorbate in proportion, and stirring thoroughly to obtain mixture.

The burn and scald are treated by clearing heat and detoxicating promoting blood circulation, detumescence, promoting granulation and relieving pain. The product of the invention is composed of a large number of medicines for clearing heat and detoxicating, clearing heat and cooling blood, clearing heat and drying dampness, promoting blood circulation and removing obstruction in collaterals, removing blood stasis and detumescence, removing putrefaction and promoting granulation, astringing and relieving pain, etc., so the product has good curative effect. And has obvious inhibiting effect on staphylococcus aureus, hemolytic streptococcus, pseudomonas aeruginosa, white staphylococcus and the like, so that the composition is effective on various surgical infectious diseases.

The beneficial effects of the invention are as follows:

The invention has the advantages that the proportion of the product enables various medicinal materials in the medicament to excite the optimal medicament effect, the interaction of the traditional Chinese medicine and western medicines is synergistic, both the symptoms and root causes are treated, the mutual restriction is realized, the toxicity is reduced, the medicament application is simple and convenient, and the medicament can be directly applied to an affected part, thereby obviously improving the healing effect of the injuries of human skin, muscle tissue, channels, bones and the like after burn and scald. Meanwhile, the preparation method is simple and easy to operate, is suitable for large-scale production, and has wide application value and economic benefit.

Drawings

The technical scheme of the application is further described below with reference to the accompanying drawings and examples.

FIG. 1 is a graph of the therapeutic effect of the product of the invention.

Detailed Description

It should be noted that, without conflict, the embodiments of the present application and features of the embodiments may be combined with each other.

In the description of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate orientations or positional relationships based on the drawings, are merely for convenience in describing the present application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the scope of the present application. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first", "a second", etc. may explicitly or implicitly include one or more such feature. In the description of the application, unless otherwise indicated, the meaning of "a plurality" is two or more.

In the description of the present application, unless explicitly stated or limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected, mechanically connected, electrically connected, directly connected, indirectly connected via an intervening medium, or in communication between two elements. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art in a specific case.

The technical scheme of the present application will be described in detail below with reference to the accompanying drawings in combination with embodiments.

Examples

Example 1

The embodiment provides a compound medicament for treating burns and scalds, which comprises the following raw materials:

Egg white protein powder which is beneficial to healing of wounds and incision and can maintain normal functions and metabolism of cells is food-grade;

antioxidant refined rapeseed oil;

an organic preservative;

Specifically, the ratio of borneol powder, catechin powder, natural indigo powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil and organic preservative is=2:2:2:2:1.5:1:50:0.25.

The borneol powder has 800 meshes, and the catechin powder, the natural indigo powder, the lithospermum powder and the egg white protein powder can also have 800 meshes.

The catechu powder, the natural indigo powder and the lithospermum powder are special grade medicinal materials, and the special grade Chinese medicinal materials are the highest grade Chinese medicinal materials, so that the quality is excellent and the medicinal effect is obvious.

Step 1, under the aseptic environment, putting borneol powder, catechu powder, natural indigo powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil and an organic preservative into an aseptic anhydrous container for mixing in proportion, and fully and uniformly stirring to obtain a mixture;

The extraction of calcium carbonate comprises placing quicklime in hot water (tap water, drinking grade), placing the container in natural environment (stirring lime water once), taking out white foam generated on water surface, and air drying to obtain pure calcium carbonate with chemical formula of CaCO ₃.

Clinical example one:

Patient Wang Mou, sex woman, age 2 years, right palm put into coal stove red fire to burn in spring, right palm and right wrist joint are dry, skin fade area about 1.5 square cm, palm upper portion, five fingers abdomen multiple blisters, epidermis defect, sweat gland is destroyed, many inflammatory cell infiltrates, whole hand red swelling, painful unable sleep, fever and fever, after using the product of the invention, wash the surface of wound with iodine wine and hydrogen peroxide first, daily application medicament five times, after 5 days, red swelling fade, blister dry scab, fade subcutaneous tissue drop, focal depression, continue iodine wine hydrogen peroxide wash the wound, continue administration medicament, 7 days later, granulation tissue in the surface of wound forms and enhances granular granulation growth, inflammatory cell infiltration is reduced, wound defect area all epithelialization, and accompanied with more neovascularization, blister scab drop, new skin is reddish, tender. The medicine is continuously used, the patient is pushed up and fallen down during the period, the affected part is subjected to secondary injury, the conditions of rupture and bleeding occur, iodine is used for disinfection, the medicine is continuously used, scab is removed after 15 days, new skin is pink and tender, skin is healed after 7 days, skin is smooth and has positive color, and the medicine spreading interval time and the times are determined according to the exudation secretion of the wound surface without absolute sterile isolation.

Example two

Calcium carbonate has effects in preventing edema, reducing inflammation, protecting vascular endothelial cells, and promoting wound healing, so that calcium carbonate has regulatory effects on nerve conduction and muscle contraction, and can maintain normal excitability of nerve muscle;

Fresh egg white which is beneficial to healing of wounds and incision and can maintain normal functions and metabolism of cells;

antioxidant refined rapeseed oil;

Potassium sorbate;

specifically, the ratio of borneol powder, catechin powder, natural indigo powder, lithospermum powder, calcium carbonate, fresh egg white, refined rapeseed oil and potassium sorbate is=2:2:2:2:1.5:1:50:0.25.

The borneol powder has a mesh number of 1000 meshes, and the catechin powder, the indigo naturalis powder and the lithospermum powder are preferably 1000 meshes.

Step 1, under the aseptic environment, firstly putting the dried radix arnebiae into refined rapeseed oil to be soaked for more than 48 hours, fishing out the radix arnebiae to obtain radix arnebiae oil, and then weighing and putting borneol powder, catechin powder, indigo naturalis powder, calcium carbonate, fresh egg white and potassium sorbate into the prepared radix arnebiae oil according to a proportion, and fully and uniformly stirring to obtain a mixture;

Clinical case two

A male sex is aged for 4 years, in winter, the chest, abdomen and perineum are seriously scalded by high-temperature oil, the injured area reaches more than 14%, western medicines are used for treating the burn for 12 months, the affected part still turns red and swells, subcutaneous muscle tissues are injured, the affected part repeatedly flows out of pus, the patient hunger and thin, has poor eyesight and drink food for a long time, the wound surface is cleaned by iodine hydrogen peroxide after the use of the medicament, 500 g of the medicament product is prepared, the whole burn and scald surface is dipped by feathers or other gentle medicament application tools, the medicament is used at any time every day, the wound is scabbed after 10 days, the alcohol is sterilized, the medicament is continuously used for 5 days, 300 g of the medicament is added, the medicament is reduced to be used three times every day, the whole wound is healed, the skin of the original affected part is smooth and level, the color is positive, and the patient returns to the spirit head.

Clinical case three

When a certain sex, female and 42 years old, in summer, the ankle is scalded by high-heat scalding oil for less than 5cm, the skin is red and swollen, the water bubble is broken along with a plurality of water bubbles, the broken part is white, the walking cannot be carried out, amoxicillin is orally taken, the external use of the lithospermum oil is not relieved, and the medicament is used after three days. When in use, firstly, the iodine-containing hydrogen peroxide is used for cleaning the wound surface, and the feather or other soft medicine application tools are used for dipping medicine to apply all the burn and scald surfaces, because the temperature is high in summer, the medicine is applied for more than ten times per day, after 7 days, red swelling and fading occur, most of the water bubbles are converged, the damaged muscle tissues of the instep and metatarsal bone parts are peeled off under the skin, the bone is hidden, the edge of the concave part of the focus is red, white meat particles are visible, the iodine-containing hydrogen peroxide is used for cleaning the wound surface and applying medicine continuously, after 7 days, the focus begins to form scabs in the concave part, the alcohol is used for cooling and sterilizing, after 5 days, the scabs gradually fall off, the medicine is used continuously, the itching is relieved during the period even with the alcohol is sterilized, the skin of the original affected part is smooth and the color is positive, and the time and the times of the interval of the medicine application are based on the exudation secretion of the wound surface without absolute sterile isolation.

The product adopts a mode of combining Chinese and western medicines, wherein the sticky colloid and the extremely astringent ingredients of the Chinese medicines can be mixed with wound exudate to form a colloid layer. Stopping exudation of the wound surface within 24 hours, and converging, drying and crusting the wound surface within 72 hours to form a layer of scab film covering the wound surface, thereby blocking the recontamination and damage of bacteria in the external air to the wound surface, and enabling the wound surface to be breathable with the outside through scab cracks;

The combination of the Chinese and the western medicines is used in combination with each other, so that exudation of wound body fluid is quickly and obviously inhibited, loss of water, electrolyte, heat energy and protein is obviously reduced, the consumption of the whole body is correspondingly reduced, and the occurrence of water electrolyte disorder, hypovolemic shock and hypovolemia is effectively prevented. After the exudation of the wound surface is stopped, the wound surface can be quickly dried and crusted by the convergence and sterilization of the medicinal powder, so that the suppurative infection and systemic infection of the wound surface are not caused, the wound surface is protected early, and the healing of the wound surface is quickened.

The active ingredients in the product have the effects of enhancing and regulating cellular immunity and humoral immunity, improving microcirculation vascular tension and reducing vascular permeability, so that capillary endothelial cells and fibroblasts are continuously generated, and the regeneration and repair of wound new skin are achieved in a short period of time. The treated cases of the product comprise moderate-severe burn, moderate-severe scald, moderate-steam scald, moderate-metal scald and high-temperature oil severe scald, and a plurality of typical burn and scald patients such as Western medicine treatment for 12 months still have no convergence, repeated pus discharge, mild electric welding radiation injury, moderate scald in a slag cooling pool are cured, and the skin of the cured affected part is smooth, has no dent, has no hyperplasia and has no melanin pigmentation.

With the above-described preferred embodiments according to the present application as a teaching, the worker skilled in the art could make various changes and modifications without departing from the scope of the technical idea of the present application. The technical scope of the present application is not limited to the contents of the specification, and must be determined according to the scope of claims.

Claims

1. A compound medicine for treating burns and scalds, characterized in that the compound medicine ingredients are composed of the following raw materials:

Borneol powder, catechu powder, indigo powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil and organic preservatives, wherein the ratio of the borneol powder, catechu powder, indigo powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil and organic preservatives is 2:2:2:2:1.5:1:50:0.25, and the molecular formula of the calcium carbonate is CaCO ₃ .

2. A compound medicine for treating burns and scalds according to claim 1, characterized in that the mesh size of the borneol powder is 800-1000 mesh.

3. A compound medicine for treating burns and scalds according to claim 2, characterized in that the catechu powder, indigo powder and lithospermum officinale powder are all special-grade medicinal materials.

4. The compound medicine for treating burns and scalds according to claim 3, characterized in that the egg white protein powder is food grade.

5. A compound medicine for treating burns and scalds according to any one of claim 4, characterized in that the organic preservative is potassium sorbate.

6. A method for preparing a compound medicine for treating burns and scalds according to claim 5, characterized in that it comprises the following steps:

Step 1, in a sterile environment, borneol powder, catechu powder, indigo powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil, and an organic preservative are mixed according to proportions, and stirred evenly to obtain a mixture;

Step 2: Place the mixture into a glass bottle and vacuum seal it for storage.

7. A method for preparing a composite medicine for treating burns and scalds according to claim 6, characterized in that, wherein, the dried roots of lithospermum in step 1 are first soaked in refined rapeseed oil for at least 48 hours, and the roots of lithospermum are fished out to obtain lithospermum oil; then borneol powder, catechu powder, indigo powder, calcium carbonate, egg white protein powder, and potassium sorbate are weighed in proportion and put into the lithospermum oil, and stirred evenly to obtain a mixture.

8. A compound medicine for treating burns and scalds according to any one of claims 1 to 5, characterized in that the egg white protein powder is replaced by fresh egg white.

9. The method for preparing a compound medicament for treating burns and scalds according to any one of claims 6-7, characterized in that the egg white protein powder is replaced by fresh egg white.