CN1200276A - Medicine for lowering blood-sugar and nourishing the heart and method for preparing same - Google Patents
Medicine for lowering blood-sugar and nourishing the heart and method for preparing same Download PDFInfo
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- CN1200276A CN1200276A CN97104388A CN97104388A CN1200276A CN 1200276 A CN1200276 A CN 1200276A CN 97104388 A CN97104388 A CN 97104388A CN 97104388 A CN97104388 A CN 97104388A CN 1200276 A CN1200276 A CN 1200276A
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Abstract
A Chinese medicine for conquering sugar and nourishing heart is composed of 30 components including pumkin, Chinese yam, carrot, Chinese wolfberry fruit, haw, sesame, semen cassiae, licorice, mint, concha ostreae, beta-cyclodextrin, oligosaccharide, sucrose ester, lentinan, konjaku flour, potassium sorbate etc., and is prepd. through squeezing separately, water extraction, ethanol extraction etc, then sterilizing, concentrating to form dissolvable granular prepn. or oral liquor.
Description
The present invention relates to a kind of Kengtang psyche-nourishing agent and preparation method thereof, this medicine can be treated diabetes, and the protection cardiovascular the invention still further relates to this medicaments preparation method.
Diabetes are common frdquently encountered diseases of serious harm human health, and diabetics surpasses 100,000,000 people in the world at present, and China is near 20,000,000, and the trend that increases is year by year arranged, and case fatality rate is only second to malignant tumor and cardiovascular diseases, is to jeopardize the third-largest disease of human life.Diabetes do not heal all the life, and complication extensively and seriously.Because insulin lacks relatively or definitely in the blood flow, cause sugar, fat, protein metabolism disorder, cause the rising of hyperglycemia, hyperlipidemia and blood viscosity, extensively microangiopathies of the whole body appears in middle and advanced stage, wherein 70-80% patient dies from the cardiovascular diseases, and diabetes kidney function failure and cerebrovascular accident are the common causes of death of middle and elderly diabetic patient.Not fairly obvious to the effect of primary disease Drug therapy both at home and abroad at present.
The purpose of this invention is to provide a kind of Kengtang psyche-nourishing agent, this medicament can spleen reinforcing nourishing the stomach, QI invigorating nourishing the liver, the kidney invigorating arresting seminal emission, slake thirst and help produce saliva blood sugar lowering, blood fat reducing, protection cardiovascular, treatment diabetes.
Another object of the present invention provides the preparation method of Kengtang psyche-nourishing agent.
For achieving the above object; the present invention takes following solution; by the theory of Chinese medical science prescription; skim the cream off milk; improve immune function of human body; the formation and the absorption of the peroxidating of the decomposition of glycogen and heteroplasia, inhibition lipid, fat are adjusted metabolism, blood sugar lowering, blood fat reducing, protection cardiovascular in the inhibition human body.
Medicament of the present invention is to be made by the raw material of following weight proportioning: pumpkin 34-36 part royal jelly 0.1-1 part Chinese yam 22-24 part red yeast rice 0.1-1 part carrot 5-6 part fresh pineapple juice (dense) 0.1-1 part sea-tangle fine powder 2-4 part β-ring-type is smart 0.1-1 part fruit of Chinese wolfberry 2-4 part propylene glycol alginate (PGA) 0.1-1 part Gorgon fruit 2-4 part protein sugar 0.1-1 part coix seed 2-4 part sucrose ester (HLB 13-16) 0.1-1 part perillaseed 2-4 part trimerization glycerol monosterate 0.1-1 part compound sugar 2-4 part acidic CMC-Na 0.1-1 part hawthorn 2-4 part WEIDUOFEN 0.1-1 part sesame 1-3 part dehydroacetic acid 0.01-0.1 part cassia seed 1-3 part mushroom polysaccharide 0.01-0.1 part Radix Glycyrrhizae 1-3 part peppermint 0.01-0.1 part konjaku powder 1-3 part potassium sorbate 0.01-0.1 part oyster 0.1-1 part CPP 0.01-0.1 part recklessly
The optimum weight proportioning of medicament stock of the present invention is: recklessly smart 0.28 part of 3.73 parts of propylene glycol alginate of the fruit of Chinese wolfberry (PGA) 0.19 portion of Gorgon fruit, 3.73 parts of protein sugars, 0.15 part of coix seed, 3.73 parts of sucrose esters (HLB 13-16) 0.14 part of perillaseed 3.73 parts of trimerization glycerol monosterates, 0.14 portion of compound sugar, 3.73 parts of acidic CMC-Na, 0.14 portion of hawthorn, 2.8 parts of WEIDUOFENs, 0.14 portion of sesame, 1.87 parts of dehydroacetic acids, 0.09 part of cassia seed, 1.87 parts of mushroom polysaccharides, 0.09 portion of Radix Glycyrrhizae, 1.87 portions of peppermints, 0.09 part of konjaku powder, 1.17 parts of potassium sorbates, 0.93 part of CPP of 0.03 portion of oyster (CPP) 0.02 part of 3.73 parts of β of 0.37 portion of sea-tangle of pumpkin 35.02 parts of royal jelly, 0.56 portion of Chinese yam, 23.35 parts of red yeast rices, 5.84 parts of fresh pineapple juices of 0.47 portion of carrot (dense) fine powder-ring-type
Medicaments preparation method of the present invention is to get Fructus Cucurbitae moschatae, Rhizoma Dioscoreae, Radix Dauci Sativae earlier to thinly slice, with 60～90 ℃ of hot water blanchings 1～2 minute, being cooled to room temperature carries out fragmentation, squeezes the juice, grind and carry out centrifugalize going out slag behind the juice, isolated residue is carried out carrying out centrifugalize again after enzyme decomposes, convert and obtain mixed liquor together handling the liquid that obtains for three times; Get Fructus Lycii, Semen Euryales, Semen Coicis, Fructus Perillae, Fructus Crataegi, Semen Sesami, Semen Cassiae, Radix Glycyrrhizae, Herba Menthae, Concha Ostreae again, added decocting 2 hours, 80～100 ℃ of water temperatures are isolated extracting solution, and surplus slag obtains extracting solution through ethanol extraction; Again with remaining Lac regis apis, Monas cuspurpureus Went (powder), fresh pineapple juice, the Thallus Laminariae (Thallus Eckloniae) essence powder, β-ring-type is smart recklessly, propylene glycol alginate, protein sugar, sucrose ester, the trimerization glycerol monosterate, oligosaccharide, acid resistance CMC-Na, WEIDUOFEN, dehydroacetic acid, lentinan, konjaku powder, potassium sorbate, phosphopeptide caseinate is dissolved in water, solution is filtered, obtain purified solution, at last with above-mentioned mixed liquor, two kinds of extracting solution and purified solution allotment are together, handle through homogenizing, the far infrared ultra high temperature sterilization (UHTS) is handled, and concentration is after low-temperature vacuum drying is made electuary.
The primary raw material that the present invention adopts has unique nutritive value and medical value.Include aminoacid, multivitamin, ten several mineral materials and the trace element of rich in protein, 17 seed amino acids, eight kinds of needed by human based on beta-carotene.Especially trace element such as phenols, pectin and soluble cellulose, selenium, chromium, zinc, copper such as plant sapogenin glycoside such as the active ingredient of the CTY that is contained in the Fructus Cucurbitae moschatae, Rhizoma Dioscoreae Saponin, flavone and sterols, tea polyphenols.These compositions not only provide certain nutrient for human body, improve immune function of human body, the formation and the absorption of the peroxidating of the decomposition of glycogen and heteroplasia, inhibition lipid, fat in the inhibition human body, and can adjust metabolism.Blood sugar lowering, blood fat reducing, blood pressure lowering there is tangible effect.
Owing to adopted the advanced technologies such as extraction, preparation, low-temperature vacuum drying of biotechnology and active ingredient to combine, each efficacy component and functional characteristic have been kept to greatest extent, add the science compatibility again, make energy complementating reinforcing between each composition, drug effect is further brought into play.
The principal character of diabetes be in the blood of human body glucose amount than normal person height.The U.S. discovers at the diabetes study center, the cause of disease of diabetes is that some cell of patient's pancreas lacks a kind of Glut-2 protein, this albumen mass-energy promotes insulin that glucose in the blood is delivered to the B cell, make blood sugar content reach normal level, according to this research, the someone finds to contain in the Fructus Cucurbitae moschatae a kind of active ingredient CTY, and this material can promote the pancreas excreting insulin, increase Glut-2 content, thereby the control of diabetes is had tangible curative effect.Contained ten various trace elements zinc, copper, chromium etc. play a part very important in the medicament of the present invention.As zinc is 100 plurality of enzymes components in the body, and this is that enzymatic activity institute is essential.Zinc is again the insulin ingredient, and the per molecule islets of langerhans have two zinc atoms, so with insulin active relation is arranged.Copper distributes with the bivalent cupric ion form in human body again, often claims serum copper, and copper and blood plasma azurin not only participate in hematopoiesis, but also participates in the special proteic synthetic of insulin B cell surface, and this albumen is above-mentioned Glut-2 protein.In addition, copper also is the conduction mediator of nervus centralis, the nerve fiber that nerve is made up of a large amount of neurons, copper ion in human body along nerve fiber with strand and the even coherent distribution of multichain form.Neuron contains certain density copper, mitochondrion, prominent can steep etc., form the electron density district, secretion of insulin is reconciled by the sympathetic nerve of nervus centralis and parasympathetic nervous, hypothalamus has the maincenter of reconciling insulin secretion in the central nervous system, electricity irritation hypothalamus ventral lateral nucleus, insulin secretion is increased, and stimulate ventromedial nucleus, then insulin secretion reduces.Human serum copper normal value is 90-130ug/dl, and according to survey, the serum copper of diabetics is on the low side or extremely low, have below 50ug/dl.This proof copper metabolism and diabetes are closely related.Chromium is trivalent (sexivalent poisonous) in human body, is the ingredient of glucose tolerance factor in blood plasma, increases tolerance and the utilization of body to glucose.So think that the glucose amount tolerance factor may be the cofactor of insulin.Scarce chromium is one of reason that causes hypertension, diabetes and coronary heart disease, and chromium not only can suppress the generation of malignant tumor in the body, also can promote the release of insulin in the body, makes diabetes patient's insulin secretion normalization.
Contain abundant vitamin C, B1, B2, B6, E, Nicotiana tabacum L. acid and β-calabash Radix Raphani element in the medicament of the present invention, they also play direct or indirect effect in the treatment diabetes.For example vitamin B6 participate in enzyme in the organism metabolism process coenzyme, it is for carbohydrate metabolism, lipid metabolism also plays an important role.This material of B6 that is deficient in vitamin in the body all has to some extent directly or indirectly influence to generation, the development of diabetes.It enhances metabolism, and makes intravital potassium and sodium keep balance, assists to urinate, and removes the function of edema and fat-reducing.The vitamin C of capacity reduces the body glycated protein in the medicament of the present invention, and glycolated hemoglobin also reduces, Profilin saccharifying, the generation that has slowed down diabetic complication.Find out that according to medical science glycated protein is the arch-criminal who produces chronic complicating diseases of diabetes.But the past is reduced glycated protein amount in the blood by various means always.
Also have Quercetin in the medicament of the present invention, this is a kind of material relevant with Citrin, has to promote vitamin C to absorb and improve the effect of blood vessel, and therefore energy coronary blood flow increasing and blood fat reducing, have blood pressure lowering and cardiac stimulant function.Also contain the speciality-calcium pectic acid fat from a kind of energy cholesterol reducing of Radix Dauci Sativae in the medicament of the present invention, calcium pectic acid fat is relevant with the bile metabolism.But the fat in the bile acid facilitating digestion diet, it is formed by cholesterol, and under normal conditions, human body is repeatedly used bile acid, and when bile acid reduced, human body must utilize the cholesterol of self to make bile acid.Calcium pectic acid fat can make most bile acids solidify according to the study.So too much cholesterol just serves as the raw material of making bile acid in the body, and after a series of metabolism, cholesterol becomes bile acid, thereby forms new " metabolic balance ", in addition, also has a kind of composition of energy blood sugar lowering in the Radix Dauci Sativae.
The total Saponin of the plant that contains in the medicament of the present invention has significant blood pressure lowering and hypoglycemic activity, disease resistance enhancemen, raise immunity as Rhizoma Dioscoreae Saponin, glycyrrhizin, Stigma Maydis Saponin etc.The mucus protein that contains in the medicament of the present invention, catechin and flavonoid, sterols, phenols etc., and glucomannan, glycyrrhizin, the pectin class, solubility vitamin etc., main control cardiovascular system diseases, the content of cholesterol and triglycerides in the reduction blood, reduce the calmness of lipid on blood vessel wall, vessel softening, suppress the activation of ACE enzyme, and promotion platelet anticoagulant, suppress the formation of the plain B2 of hematic acid simultaneously, reduce cellulosic level in the blood, it is atherosis to have a prevention, bring high blood pressure down, blood fat, the control thrombosis, multiple function such as anti-diabetic.
The gamma-Linolenic acid, the alpha-linolenic acid that contain in the medicament of the present invention are essential fatty acid, and materials such as the same calcium of these compositions, iodine improve nervous function together, recover the diabetes nerve infringement.Can also reduce plasma cholesterol and triglycerides and suppress platelet aggregation in the body, reduce thrombosis.
With medicament of the present invention 100 diabeticss are done clinical trial, that obtains significant curative effect accounts for 55%, substantially effectively accounts for 40%, and invalid accounts for 5%, and total effective rate reaches 95%.
Embodiment
Get raw material by following proportioning: recklessly smart 0.28 kilogram of 3.73 kilograms of propylene glycol alginate of the fruit of Chinese wolfberry (PGA) 0.19 kilogram of Gorgon fruit, 3.73 kilograms of protein sugars, 0.15 kilogram of coix seed, 3.73 kilograms of sucrose esters (HLB 13-16) 0.14 kilogram of perillaseed 3.73 kilograms of trimerization glycerol monosterates, 0.14 kilogram of compound sugar, 3.73 kilograms of acidic CMC-Na, 0.14 kilogram of hawthorn, 2.8 kilograms of WEIDUOFENs, 0.14 kilogram of sesame, 1.87 kilograms of dehydroacetic acids, 0.09 kilogram of cassia seed, 1.87 kilograms of mushroom polysaccharides, 0.09 kilogram of Radix Glycyrrhizae, 1.87 kilograms of peppermints, 0.09 kilogram of konjaku powder, 1.17 kilograms of potassium sorbates, 0.93 kilogram of CPP of 0.03 kilogram of oyster (CPP) 0.02 kilogram of 3.73 kilograms of β of 0.37 kilogram of sea-tangle fine powder of pumpkin 35.02 kilograms of royal jelly, 0.56 kilogram of Chinese yam, 23.35 kilograms of red yeast rices, 5.84 kilograms of fresh pineapple juices of 0.47 kilogram of carrot (dense)-ring-type
Preparation method is as follows:
Get Fructus Cucurbitae moschatae, Rhizoma Dioscoreae, Radix Dauci Sativae earlier and thinly slice (above-mentioned raw materials preferably uses fresh raw material), with 85 ℃ of hot water blanchings 2 minutes, being cooled to room temperature (20～25 ℃ best) carries out fragmentation, squeezes the juice, grind and carry out centrifugalize going out slag behind the juice, isolated residue is carried out carrying out centrifugalize again after enzyme decomposes, convert and obtain mixed liquor together handling the liquid that obtains for three times; Get Fructus Lycii, Semen Euryales, Semen Coicis, Fructus Perillae, Fructus Crataegi, Semen Sesami, Semen Cassiae, Radix Glycyrrhizae, Herba Menthae, Concha Ostreae again, added decocting 2 hours (water should cover 100 millimeters of powder), 100 ℃ of water temperatures are isolated extracting solution, surplus slag obtains extracting solution through ethanol extraction (extracting routinely); Again with remaining Lac regis apis, Monas cuspurpureus Went (powder), fresh pineapple juice (getting 5 times of concentrated juice), the Thallus Laminariae (Thallus Eckloniae) essence powder, β-ring-type is smart recklessly, propylene glycol alginate, protein sugar, sucrose ester, the trimerization glycerol monosterate, oligosaccharide, acid resistance CMC-Na (claiming the acid resistance sodium carboxymethyl cellulose again), WEIDUOFEN, dehydroacetic acid, lentinan, konjaku powder, potassium sorbate, phosphopeptide caseinate is dissolved in water, solution is filtered, obtain purified solution, at last with above-mentioned mixed liquor, two kinds of extracting solution and purified solution allotment are together, handle through homogenizing, the far infrared ultra high temperature sterilization (UHTS) is handled, and concentration is after low-temperature vacuum drying is made electuary.Can also use the concentrated solution after filling apparatus is handled the far infrared ultra high temperature sterilization (UHTS) to make oral liquid.
Claims (6)
1, a kind of Kengtang psyche-nourishing agent is characterized in that it is recklessly smart 0.1-1 part fruit of Chinese wolfberry 2-4 part propylene glycol alginate (PGA) 0.1-1 part Gorgon fruit 2-4 part protein sugar 0.1-1 part coix seed 2-4 part sucrose ester (HLB 13-16) 0.1-1 part perillaseed 2-4 part trimerization glycerol monosterate 0.1-1 part compound sugar 2-4 part acidic CMC-Na 0.1-1 part hawthorn 2-4 part WEIDUOFEN 0.1-1 part sesame 1-3 part dehydroacetic acid 0.01-0.1 part cassia seed 1-3 part mushroom polysaccharide 0.01-0.1 part Radix Glycyrrhizae 1-3 part peppermint 0.01-0.1 part konjaku powder 1-3 part potassium sorbate 0.01-0.1 part oyster 0.1-1 part CPP 0.01-0.1 part of medicament pumpkin 34-36 part royal jelly 0.1-1 part Chinese yam 22-24 part red yeast rice 0.1-1 part carrot 5-6 part fresh pineapple juice (dense) 0.1-1 part sea-tangle fine powder 2-4 part β of being made by the raw material of following weight proportioning-ring-type
2, Kengtang psyche-nourishing agent according to claim 1, wherein the weight proportion of each raw material is recklessly smart 0.28 part of 3.73 parts of propylene glycol alginate of the fruit of Chinese wolfberry (PGA) 0.19 portion of Gorgon fruit, 3.73 parts of protein sugars, 0.15 part of coix seed, 3.73 parts of sucrose esters (HLB 13-16) 0.14 part of perillaseed 3.73 parts of trimerization glycerol monosterates, 0.14 portion of compound sugar, 3.73 parts of acidic CMC-Na, 0.14 portion of hawthorn, 2.8 parts of WEIDUOFENs, 0.14 portion of sesame, 1.87 parts of dehydroacetic acids, 0.09 part of cassia seed, 1.87 parts of mushroom polysaccharides, 0.09 portion of Radix Glycyrrhizae, 1.87 portions of peppermints, 0.09 part of konjaku powder, 1.17 parts of potassium sorbates, 0.93 part of CPP of 0.03 portion of oyster (CPP) 0.02 part of 3.73 parts of β of 0.37 portion of sea-tangle of pumpkin 35.02 parts of royal jelly, 0.56 portion of Chinese yam, 23.35 parts of red yeast rices, 5.84 parts of fresh pineapple juices of 0.47 portion of carrot (dense) fine powder-ring-type
3, Kengtang psyche-nourishing agent according to claim 1 and 2 is characterized in that described medicament is an electuary.
4, Kengtang psyche-nourishing agent according to claim 1 and 2 is characterized in that described medicament is an oral liquid.
5, according to the preparation method of the described Kengtang psyche-nourishing agent of claim 3, it is characterized in that getting earlier Fructus Cucurbitae moschatae, Rhizoma Dioscoreae, Radix Dauci Sativae thinly slices, with 60～90 ℃ of hot water blanchings 1～2 minute, being cooled to room temperature carries out fragmentation, squeezes the juice, grind and carry out centrifugalize going out slag behind the juice, isolated residue is carried out carrying out centrifugalize again after enzyme decomposes, convert and obtain mixed liquor together handling the liquid that obtains for three times; Get Fructus Lycii, Semen Euryales, Semen Coicis, Fructus Perillae, Fructus Crataegi, Semen Sesami, Semen Cassiae, Radix Glycyrrhizae, Herba Menthae, Concha Ostreae again, added decocting 2 hours, 80～100 ℃ of water temperatures are isolated extracting solution, and surplus slag obtains extracting solution through ethanol extraction; Again with remaining Lac regis apis, Monas cuspurpureus Went (powder), fresh pineapple juice, the Thallus Laminariae (Thallus Eckloniae) essence powder, β-ring-type is smart recklessly, propylene glycol alginate, protein sugar, sucrose ester, the trimerization glycerol monosterate, oligosaccharide, acid resistance CMC-Na, WEIDUOFEN, dehydroacetic acid, lentinan, konjaku powder, potassium sorbate, phosphopeptide caseinate is dissolved in water, solution is filtered, obtain purified solution, at last with above-mentioned mixed liquor, two kinds of extracting solution and purified solution allotment are together, handle through homogenizing, the far infrared ultra high temperature sterilization (UHTS) is handled, and concentration is after low-temperature vacuum drying is made electuary.
6,, it is characterized in that using the concentrated solution after filling apparatus is handled the far infrared ultra high temperature sterilization (UHTS) to make oral liquid according to the preparation method of the described Kengtang psyche-nourishing agent of claim 5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97104388A CN1084193C (en) | 1997-05-23 | 1997-05-23 | Medicine for lowering blood-sugar and nourishing the heart and method for preparing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97104388A CN1084193C (en) | 1997-05-23 | 1997-05-23 | Medicine for lowering blood-sugar and nourishing the heart and method for preparing same |
Publications (2)
| Publication Number | Publication Date |
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| CN1200276A true CN1200276A (en) | 1998-12-02 |
| CN1084193C CN1084193C (en) | 2002-05-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN97104388A Expired - Fee Related CN1084193C (en) | 1997-05-23 | 1997-05-23 | Medicine for lowering blood-sugar and nourishing the heart and method for preparing same |
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| CN (1) | CN1084193C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1072908C (en) * | 1999-09-07 | 2001-10-17 | 朱长征 | Food additive benefiting patients of diabetics, coronary heart disease and tumor and its preparing method |
| CN101269211B (en) * | 2007-03-23 | 2011-08-10 | 天津天狮生物工程有限公司 | Shuangtang high calcium medicinal granule and preparation technique |
| CN103110103A (en) * | 2013-03-13 | 2013-05-22 | 广州朗姿贸易有限公司 | Nutritious food powder for clearing fat and losing weight |
| CN106047654A (en) * | 2016-06-21 | 2016-10-26 | 江苏食品药品职业技术学院 | Vinegar drink with function of assistance on blood lipid reduction, and preparation method of vinegar drink |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1094302A (en) * | 1993-04-29 | 1994-11-02 | 辽宁高新技术研究设计院 | A kind of pure Chinese medicine oral liquid |
| CN1090193A (en) * | 1993-05-03 | 1994-08-03 | 孙志远 | The medicine and the production method of treatment diabetes |
| CN1087009A (en) * | 1993-08-05 | 1994-05-25 | 汪亚利 | Food for dietary of diabetic and compound method thereof |
| CN1097272A (en) * | 1993-12-03 | 1995-01-18 | 王若浩 | Ganoderma tea |
| CN1106371A (en) * | 1994-02-03 | 1995-08-09 | 杨先春 | Catalytic degradation of waste polystyrene into phenylethylene |
-
1997
- 1997-05-23 CN CN97104388A patent/CN1084193C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1072908C (en) * | 1999-09-07 | 2001-10-17 | 朱长征 | Food additive benefiting patients of diabetics, coronary heart disease and tumor and its preparing method |
| CN101269211B (en) * | 2007-03-23 | 2011-08-10 | 天津天狮生物工程有限公司 | Shuangtang high calcium medicinal granule and preparation technique |
| CN103110103A (en) * | 2013-03-13 | 2013-05-22 | 广州朗姿贸易有限公司 | Nutritious food powder for clearing fat and losing weight |
| CN106047654A (en) * | 2016-06-21 | 2016-10-26 | 江苏食品药品职业技术学院 | Vinegar drink with function of assistance on blood lipid reduction, and preparation method of vinegar drink |
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| Publication number | Publication date |
|---|---|
| CN1084193C (en) | 2002-05-08 |
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