CN119873418A - Continuous biochip detection device - Google Patents

Continuous biochip detection device Download PDF

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Publication number
CN119873418A
CN119873418A CN202510345906.5A CN202510345906A CN119873418A CN 119873418 A CN119873418 A CN 119873418A CN 202510345906 A CN202510345906 A CN 202510345906A CN 119873418 A CN119873418 A CN 119873418A
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CN
China
Prior art keywords
biochip
driving
plate
dust
close
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202510345906.5A
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Chinese (zh)
Other versions
CN119873418B (en
Inventor
苏永涛
黄春丽
姜昱
朱先伟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jinan Holcim's Biological Technology Co ltd
Shandong Second Medical University
Original Assignee
Shandong Second Medical University
Jinan Holcim's Biological Technology Co ltd
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Filing date
Publication date
Application filed by Shandong Second Medical University, Jinan Holcim's Biological Technology Co ltd filed Critical Shandong Second Medical University
Priority to CN202510345906.5A priority Critical patent/CN119873418B/en
Publication of CN119873418A publication Critical patent/CN119873418A/en
Application granted granted Critical
Publication of CN119873418B publication Critical patent/CN119873418B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G65/00Loading or unloading
    • B65G65/30Methods or devices for filling or emptying bunkers, hoppers, tanks, or like containers, of interest apart from their use in particular chemical or physical processes or their application in particular machines, e.g. not covered by a single other subclass
    • B65G65/32Filling devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B5/00Cleaning by methods involving the use of air flow or gas flow
    • B08B5/02Cleaning by the force of jets, e.g. blowing-out cavities
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G29/00Rotary conveyors, e.g. rotating discs, arms, star-wheels or cones
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G47/00Article or material-handling devices associated with conveyors; Methods employing such devices
    • B65G47/74Feeding, transfer, or discharging devices of particular kinds or types

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention relates to the technical field of detection devices and discloses a biochip continuous detection device which comprises a base and a plurality of supporting legs fixedly arranged on the lower surface of the base at equal intervals, wherein a rotating shaft is rotatably arranged on the upper surface of the middle position of the base, and a rotating table is fixedly arranged at the top end of the rotating shaft. According to the device, the push rod drives the compression plate to compress air in the compression box, the air in the compression box enters the dust hood through the air outlet end, so that dust adhered to the outer surface of the biochip is blown off by the air, meanwhile, the sector gear drives the clean biochip to turn over to the inside of the dust hood through the driven gear and the rotating plate, the dust adhered to the surface of the biochip can be cleaned up through the device, the dust is located in a dust-free environment during detection, the dust is prevented from shielding probes on the surface of the biochip, and the sensitivity and the accuracy of detection are ensured.

Description

Continuous biochip detection device
Technical Field
The invention relates to the technical field of detection devices, in particular to a biochip continuous detection device.
Background
The biochip is a product of modern micro-processing technology and biotechnology, and is a micro device which is manufactured inside or on the surface of a flat carrier through photoetching or biomolecule self-assembly technology and can complete certain biological reaction functions. According to different applications, biochips are mainly divided into two major categories, namely, bioelectronic chips, which are used for manufacturing bioelectronic products such as biocmputers. The other is a bioanalytical chip for the manipulation of various biological macromolecules, cellular tissues and biochemical reaction detection.
The existing biochip detection device (bulletin number: CN 112896769A) has at least the following disadvantages:
Above-mentioned patent is when using, through setting up the connecting rod on the case lid, when needs use, open the case lid, make the case lid drive the connecting rod rotate, make the connecting rod drive the fixing base of connection remove, make the T type slider on the movable plate that the fixing base is connected can slide in the spout, make the movable plate upwards remove in can follow the box under the drive of apron, make the check out test set on the movable plate can stretch out from the box, portable detects, because the detection of biochip in above patent is gone on in external environment, dust that will bond at the surface of biochip before detecting is clear away, the dust can cover at the biochip surface, cause shielding to the probe on biochip surface, result in losing or the weakness of signal, thereby influence the sensitivity and the accuracy of detection.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a biochip continuous detection device.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
The utility model provides a biochip continuous detection device, includes base and equidistance fixed mounting in many landing legs of base lower surface, the upper surface rotation of base intermediate position installs the pivot, the top fixed mounting of pivot has the revolving stage, four opening has been run through to the circumferencial direction equidistance of revolving stage upper surface, four all rotate between the open-ended inner wall and install the revolving plate, the surface of revolving plate one side is provided with biochip, the circumference surface fixed mounting of base has C type frame, the lower fixed surface that C type frame is close to the top has the dust cover, the bottom of dust cover is leveled with the upper surface of revolving stage, the dust cover sets up in the top of two adjacent revolving plates, the terminal surface that the dust cover is close to both ends all fixed mounting has the sunshade, the surface of sunshade is greater than the surface of revolving plate, the upper surface fixed mounting of base has the dust cover, the top of dust cover is leveled with the lower surface subsides of revolving stage, the dust cover sets up under and with its overlapping a revolving plate setting, the upper surface fixed mounting of dust cover has optical detection lens to run through in the top wall of top of the dust cover.
As a further scheme of the invention, a compression box is fixedly arranged on the outer surface of one side of the dust hood, which is close to the rotating shaft, a compression plate is slidably arranged on the inner wall of the compression box, a push rod is fixedly arranged on the outer surface of one side of the compression plate, which is close to the rotating shaft, a driving column is fixedly arranged on the upper surface of the other end of the push rod, a driving disk is fixedly arranged on the circumferential outer surface of the rotating shaft, which is close to the top end, a cam driving groove is formed in the lower surface of the driving disk, the driving column is slidably arranged on the inner wall of the cam driving groove, and the cam driving groove consists of four convex grooves and four grooves alternately.
As a further scheme of the invention, the air outlet end of the compression box penetrates through the inner wall of the dust hood and is communicated with the inside of the dust hood, the outer surface of one side of the compression plate is fixedly provided with a one-way air inlet valve, the air inlet end of the one-way air inlet valve is provided with an air filter element, the outer surface of one side of the dust hood opposite to the compression box is provided with a one-way air outlet valve, and the air outlet end of the compression box is arranged below the rotating plate.
As a further scheme of the invention, a plurality of fixed blocks are fixedly arranged on the circumferential outer surface of the turntable, a driven gear is fixedly arranged at one end of the rotating plate penetrating through the outer surface of the fixed block, a fixed shaft is fixedly arranged on the outer surface of one side of the fixed block, a sector gear is rotatably arranged on the circumferential outer surface of the fixed shaft and meshed with the driven gear, an eccentric block is fixedly arranged on the outer surface of the sector gear, and a sliding column is fixedly arranged on the outer surface of the other end of the eccentric block.
As a further scheme of the invention, the inner wall of the C-shaped frame is fixedly provided with the driving ring, the upper surface of the driving ring is provided with a bulge, the bulge is arranged on the driving ring and is close to the upper surface of the dust cover, the sliding column is abutted against the upper surface of the driving ring, one end of the fixed shaft penetrates through the outer surface of the sector gear to be sleeved with the torsion spring, one end of the torsion spring is fixedly connected with the circumferential outer surface of the fixed shaft, and the other end of the torsion spring is fixedly connected with the outer surface of the sector gear.
As a further scheme of the invention, the outer surface of the rotating plate, which is positioned at one side of the biochip, is provided with a mounting sink groove, the inner wall of the mounting sink groove is symmetrically and rotatably provided with two L-shaped clamping rods, the outer surfaces of the two L-shaped clamping rods, which are close to one end of the sliding column, are fixedly provided with clamping columns, the circumferential outer surfaces of the clamping columns are provided with annular clamping grooves, the biochip is arranged between the inner walls of the annular clamping grooves, the inner wall of the mounting sink groove is provided with a sliding groove, the inner wall of the sliding groove is slidably provided with a sliding block, the top end of the sliding block is fixedly provided with a moving plate, the outer surface of the moving plate is symmetrically provided with two guide grooves, the outer surface of the other end of the L-shaped clamping rods is fixedly provided with a guide column, the guide column is slidably arranged with the inner wall of the guide groove, and the outer surface of the rotating plate, which is far away from one end of the driven gear, is provided with a stop block.
As a further scheme of the invention, a sliding rod is fixedly arranged on the outer surface of one side of the sliding block, which is close to the driven gear, a blocking head is fixedly arranged on the other end of the sliding rod, which penetrates through the end surface of one end of the rotating plate, which is close to the driven gear, the blocking head is arranged below the driving ring, a bump is fixedly arranged on the outer surface of one side of the driving ring, which is opposite to the dust hood, the blocking head is propped against the outer surface of the bump, a spring is sleeved on the outer surface of the sliding rod, and the spring is arranged between the sliding block and the inner wall of the sliding groove, which is close to the driven gear.
As a further scheme of the invention, the bottom end of the rotating shaft penetrates through the lower surface of the base to fixedly install a driven sheave, the lower surface of the base is rotatably provided with a driving plate, the driving plate is meshed with the driven sheave, the lower surface of the base is fixedly provided with a shell, the lower surface of the shell is fixedly provided with a driving motor, the output end of the driving motor penetrates through the outer surface of the shell to fixedly install with the rotation center of the driving plate, and four radial grooves are formed in the circumferential direction of the outer surface of the driven sheave at equal intervals.
Compared with the prior art, the invention has the following beneficial effects:
1. The push rod drives the compression plate to compress air in the compression box, the air in the compression box enters the dust hood through the air outlet end, so that dust adhered to the outer surface of the biochip is blown off by the air, meanwhile, the sector gear drives the clean biochip to turn over to the inside of the dust hood through the driven gear and the rotating plate, the dust adhered to the surface of the biochip can be cleaned up through the device, the dust is positioned in a dust-free environment during detection, the dust is prevented from shielding probes on the surface of the biochip, and the sensitivity and the accuracy of detection are ensured;
2. The slide bar drives the motion board to move close to the lug through the slider, and the motion board drives two L type clamp levers through guide pillar and guide slot and keeps away from each other and move, and two L type clamp levers drive the clamp post and keep away from each other and move, and at this moment, the biochip that is limited by two clamp posts is released and falls into in the collection box, the follow-up centralized processing of being convenient for.
Drawings
FIG. 1 is a schematic diagram showing the overall structure of a continuous biochip detecting apparatus according to the present invention;
FIG. 2 is a schematic diagram showing the bottom view of a continuous biochip detecting apparatus according to the present invention;
FIG. 3 is a schematic view of an active plate of a continuous biochip detecting apparatus according to the present invention;
FIG. 4 is a schematic diagram of a driving disc of a continuous biochip detecting apparatus according to the present invention;
FIG. 5 is a schematic top view of a continuous biochip detecting apparatus according to the present invention;
FIG. 6 is a schematic view of a dust hood of a biochip continuous detection apparatus according to the present invention;
FIG. 7 is a schematic diagram of a rotating plate of a continuous biochip measuring apparatus according to the present invention;
FIG. 8 is a schematic view of an L-shaped clamping rod of a continuous biochip detecting apparatus according to the present invention;
FIG. 9 is a schematic diagram of a driving ring of a continuous biochip detecting apparatus according to the present invention;
FIG. 10 is an enlarged schematic view of a portion of FIG. 4A;
FIG. 11 is an enlarged schematic view of a portion of FIG. 3B;
fig. 12 is a schematic view of a dust cover of a biochip continuous detection apparatus according to the present invention.
In the figure, 1, a base, 2, a turntable, 201, an opening, 3, a dust cover, 301, a shielding plate, 4, an optical detection lens, 5, a C-shaped frame, 6, a dust cover, 7, a driving ring, 701, a bulge, 702, a lug, 8, a shell, 9, a driving motor, 10, a driving dial, 11, a driven grooved pulley, 12, a rotating plate, 13, a compression box, 14, a compression plate, 15, a push rod, 16, a one-way air inlet valve, 17, a driving post, 18, a one-way air outlet valve, 19, a driving disc, 20, a cam driving groove, 21, a mounting sink, 22, a stop, 23, an L-shaped clamping rod, 24, a slide rod, 25, a spring, 26, a clamping post, 27, a slide block, 2701, a slide groove, 28, a guide post, 29, a guide groove, 30, a blocking head, 31, a fixed block, 32, a driven gear, a sector gear, 34, a torsion spring, 35 and a slide post.
Detailed Description
The invention is further described in connection with the following detailed description, in order to make the technical means, the creation characteristics, the achievement of the purpose and the effect of the invention easy to understand.
In the description of the present invention, it should be noted that the directions or positional relationships indicated by the terms "upper", "lower", "inner", "outer", "front", "rear", "both ends", "one end", "the other end", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present invention and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific direction, be configured and operated in the specific direction, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, unless explicitly stated or limited otherwise, the terms "mounted," "configured to," "connected," and the like are to be construed broadly as, for example, "connected" may be fixedly connected, may be detachably connected, or integrally connected, may be mechanically connected or electrically connected, may be directly connected or indirectly connected through an intermediate medium, and may be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.
Referring to fig. 1-12, a biochip continuous detecting apparatus comprises a base 1 and a plurality of supporting legs fixedly mounted on the lower surface of the base 1 at equal intervals, wherein a rotating shaft is rotatably mounted on the upper surface of the middle position of the base 1, a turntable 2 is fixedly mounted on the top end of the rotating shaft, four openings 201 are formed in the circumferential direction of the upper surface of the turntable 2 in an equidistant penetrating manner, a rotating plate 12 is rotatably mounted between the inner walls of the four openings 201, a biochip is arranged on the outer surface of one side of the rotating plate 12, a C-shaped frame 5 is fixedly mounted on the circumferential outer surface of the base 1, a dust cover 3 is fixedly mounted on the lower surface of the C-shaped frame 5 near the top end, the bottom end of the dust cover 3 is flatly attached to the upper surface of the turntable 2, the dust cover 3 is arranged above the two adjacent rotating plates 12, a shielding plate 301 is fixedly mounted on the end surfaces of the dust cover 3 near the two ends, the surface of the shielding plate 301 is larger than the surface of the rotating plate 12, the upper surface of the base 1 is fixedly provided with a dust hood 6, the top end of the dust hood 6 is flatly attached to the lower surface of the rotary table 2, the dust hood 6 is arranged right below the dust hood 3 and is overlapped with the rotary table 12, the upper surface of the dust hood 3 is fixedly provided with an optical detection lens 4, the bottom end of the optical detection lens 4 penetrates through the top wall of the dust hood 3 and is arranged right above the rotary table 12, the outer surface of the dust hood 6 close to one side of a rotating shaft is fixedly provided with a compression box 13, the inner wall of the compression box 13 is slidably provided with a compression plate 14, the outer surface of the compression plate 14 close to one side of the rotating shaft is fixedly provided with a push rod 15, the upper surface of the other end of the push rod 15 is fixedly provided with a driving column 17, the circumference outer surface of the rotating shaft close to the top end is fixedly provided with a driving disk 19, the lower surface of the driving disk 19 is provided with a cam driving groove 20, the driving column 17 is slidably arranged with the inner wall of the cam driving groove 20, the cam driving groove 20 is formed by four convex grooves and four grooves alternately, the air outlet end of the compression box 13 penetrates through the inner wall of the dust hood 6 and is communicated with the inside of the dust hood, the one-way air inlet valve 16 is fixedly arranged on the outer surface of one side of the compression plate 14, an air filter core is arranged at the air inlet end of the one-way air inlet valve 16, the one-way air outlet valve 18 is arranged on the outer surface of one side of the dust hood 6 opposite to the compression box 13, and the air outlet end of the compression box 13 is arranged below the rotary plate 12.
The driving disc 19 is driven to rotate through the rotating shaft, the driving disc 19 is matched with the driving column 17 through the cam driving groove 20, the push rod 15 drives the compression plate 14 to compress air inside the compression box 13, the air inside the compression box 13 enters into the dust hood 6 through the air outlet end, the outer surface of the biochip can be cleaned by blown air, dust adhered to the outer surface of the biochip is blown off by the air, the blown dust can be discharged from the one-way air outlet valve 18, and the dust adhered to the surface of the biochip can be blown off and cleaned up through the device.
In this embodiment, a plurality of fixed blocks 31 are fixedly installed on the circumferential outer surface of the turntable 2, a driven gear 32 is fixedly installed on one end of the rotating plate 12 penetrating through the outer surface of the fixed blocks 31, a fixed shaft is fixedly installed on the outer surface of one side of the fixed blocks 31, a sector gear 33 is rotatably installed on the circumferential outer surface of the fixed shaft, the sector gear 33 is meshed with the driven gear 32, an eccentric block is fixedly installed on the outer surface of the sector gear 33, a sliding column 35 is fixedly installed on the outer surface of the other end of the eccentric block, a driving ring 7 is fixedly installed on the inner wall of the C-shaped frame 5, a protrusion 701 is arranged on the upper surface of the driving ring 7, the protrusion 701 is arranged on the driving ring 7 and is close to the upper surface of the dust cover 3, the sliding column 35 abuts against the upper surface of the driving ring 7, a torsion spring 34 is sleeved on one end of the fixed shaft penetrating through the outer surface of the sector gear 33, one end of the torsion spring 34 is fixedly connected with the circumferential outer surface of the fixed shaft, and the other end of the torsion spring 34 is fixedly connected with the outer surface of the sector gear 33.
When the slide column 35 moves to the position of the bulge 701 of the driving ring 7, the slide column 35 drives the sector gear 33 to rotate, the sector gear 33 drives the rotating plate 12 to rotate 180 degrees through the driven gear 32, at the moment, the clean biochip can be overturned to the inside of the dust cover 3, the tiny probes on the biochip are detected through the optical detection lens 4, the dust adhered to the surface of the biochip can be cleaned up through the device, the dust is positioned in a dust-free environment during detection, the probes on the surface of the biochip are prevented from being shielded by the dust, and the detection sensitivity and accuracy are ensured.
In this embodiment, the outer surface of the rotating plate 12 on one side of the biochip is provided with a mounting sink 21, the inner wall of the mounting sink 21 is symmetrically and rotatably provided with two L-shaped clamping rods 23, the outer surfaces of one ends of the two L-shaped clamping rods 23 close to the sliding columns 35 are fixedly provided with clamping columns 26, the circumferential outer surface of each clamping column 26 is provided with an annular clamping groove, the biochip is arranged between the inner walls of the annular clamping grooves, the inner wall of the mounting sink 21 is provided with a sliding groove 2701, the inner wall of the sliding groove 2701 is slidably provided with a sliding block 27, the top end of the sliding block 27 is fixedly provided with a moving plate, the outer surface of the moving plate is symmetrically provided with two guide grooves 29, the outer surface of the other ends of the L-shaped clamping rods 23 is fixedly provided with a guide post 28, the inner wall of the guide groove 29 is slidably provided with a stop 22, the outer surface of the rotating plate 12 far from one end of the driven gear 32 is provided with a stop 22, the outer surface of the sliding block 27 close to one side of the driven gear 32 is fixedly provided with a sliding rod 24, the other ends of the sliding rod 24 penetrate through the rotating plate 12 and are fixedly provided with a stop 30 near one end of the driven gear 32, the end of the sliding block 30 is arranged below the driving ring 7, the driving ring 7 is fixedly provided with a sliding block 2701, the outer surface of the driving ring 7 is opposite to the outer surface of the driven gear 6 is fixedly provided with a spring 702, the outer surface of the driving ring 702 is close to the spring 702 is provided with a stop lug 25, and the stop lug 25 is arranged between the outer surface of the spring 702 and the stop sleeve is close to the outer surface of the spring 702 is close to the spring 702.
When the blocking head 30 moves to the convex block 702 on the lower surface of the driving ring 7, the blocking head 30 is abutted against the convex block 702, the sliding rod 24 is driven by the blocking head 30 to move close to the convex block 702, the sliding rod 24 is driven by the sliding block 27 to move close to the convex block 702, the moving plate drives the two L-shaped clamping rods 23 to move away from each other through the guide posts 28 and the guide grooves 29, the two L-shaped clamping rods 23 drive the clamping columns 26 to move away from each other, and at the moment, the biochip limited by the two clamping columns 26 is released and falls into the collecting box, so that subsequent centralized processing is facilitated.
In this embodiment, the bottom of the pivot runs through the lower surface fixed mounting of base 1 and has driven sheave 11, the lower surface rotation of base 1 installs initiative driver plate 10, initiative driver plate 10 meshes with driven sheave 11, the lower surface fixed mounting of base 1 has casing 8, the lower surface fixed mounting of casing 8 has driving motor 9, the output of driving motor 9 runs through the surface of casing 8 and the rotation center fixed mounting of initiative driver plate 10, the circumferencial direction equidistance of driven sheave 11 surface is provided with four radial grooves, drive initiative driver plate 10 through driving motor 9 and rotate, initiative driver plate 10 drives the pivot intermittent type through driven sheave 11 and rotates 90, drive revolving stage 2 intermittent type through the pivot and rotate 90.
When the device is used, an operator inserts the biochip into the annular clamping grooves of the two clamping posts 26, one end of the biochip is propped against the stop block 22, the guide posts 28 pass through the guide grooves 29 by the acting force of the springs 25, the L-shaped clamping rods 23 are driven to clamp the biochip, and the device is convenient for rapidly limiting the position of the biochip and facilitating the subsequent detection;
The driving plate 10 is driven to rotate by the driving motor 9, the driving plate 10 drives the rotating shaft to intermittently rotate by 90 degrees through the driven grooved pulley 11, the rotating table 2 is driven to intermittently rotate by 90 degrees through the rotating shaft, the rotating table 2 drives the rotating plate 12 to intermittently rotate by 90 degrees to the inside of the dust hood 6, the rotating plate 12 drives the biochip to simultaneously move to the inside of the dust hood 6, when the biochip just moves to the inside of the dust hood 6, the driving plate 19 is driven to rotate through the rotating shaft because the rotating table 2 still rotates, the driving plate 19 drives the compressing plate 14 to compress air in the compressing box 13 through the cooperation of the cam driving groove 20 and the driving column 17, the air in the compressing box 13 enters the inside of the dust hood 6 through the air outlet end, and the blown air can clean the outer surface of the biochip, the dust adhered to the outer surface of the biochip is blown off by air, the blown dust is discharged from the one-way air outlet valve 18, meanwhile, the slide column 35 is driven to move by the rotary table 2, when the slide column 35 moves to the position of the bulge 701 of the driving ring 7, the slide column 35 drives the sector gear 33 to rotate, the sector gear 33 drives the rotary plate 12 to rotate 180 degrees by the driven gear 32, at the moment, the clean biochip can be turned over to the inside of the dust cover 3, then the tiny probes on the biochip are detected by the optical detection lens 4, the dust adhered to the surface of the biochip can be cleaned by the device, and the dust is prevented from shielding the probes on the surface of the biochip when the dust is detected, so that the sensitivity and the accuracy of the detection are ensured;
Meanwhile, when the blocking head 30 moves to the convex block 702 on the lower surface of the driving ring 7, the blocking head 30 is abutted against the convex block 702, the sliding rod 24 is driven by the blocking head 30 to move close to the convex block 702, the sliding rod 24 is driven by the sliding block 27 to move close to the convex block 702, the moving plate drives the two L-shaped clamping rods 23 to move away from each other through the guide posts 28 and the guide grooves 29, the two L-shaped clamping rods 23 drive the clamping posts 26 to move away from each other, and at the moment, the biochip limited by the two clamping posts 26 is released and falls into the collecting box, so that subsequent centralized processing is facilitated.
The foregoing has shown and described the basic principles and main features of the present invention and the advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present invention, and various changes and modifications may be made without departing from the spirit and scope of the invention, which is defined in the appended claims.

Claims (8)

1. The utility model provides a biochip continuous detection device, includes base (1) and equidistance fixed mounting in many landing legs of base (1) lower surface, its characterized in that, the upper surface rotation of base (1) intermediate position is installed the pivot, the top fixed mounting of pivot has revolving stage (2), four opening (201) have been run through to the circumferencial direction equidistance of revolving stage (2) upper surface, four all rotate between the inner wall of opening (201) and install revolving plate (12), the surface of revolving plate (12) one side is provided with biochip, the circumference surface fixed mounting of base (1) has C type frame (5), the lower surface fixed mounting that C type frame (5) is close to the top has dust cover (3), the bottom of dust cover (3) is pasted with the upper surface of revolving stage (2), dust cover (3) are arranged in the top of two adjacent revolving plates (12), the terminal surface that dust cover (3) are close to both ends all fixed mounting has shutter (301), the surface of shutter (301) is greater than the surface of revolving plate (12), the surface of base (1) is close to the upper surface of dust cover (6) and is provided with dust cover (6) under the dust cover (6) and the top of revolving stage (2), the upper surface fixed mounting of dust cover (3) has optical detection lens (4), the bottom of optical detection lens (4) runs through dust cover (3) roof and sets up in revolving board (12) directly over.
2. The biochip continuous detection device according to claim 1, characterized in that the outer surface of the dust hood (6) close to one side of the rotating shaft is fixedly provided with a compression box (13), the inner wall of the compression box (13) is slidably provided with a compression plate (14), the outer surface of the compression plate (14) close to one side of the rotating shaft is fixedly provided with a push rod (15), the upper surface of the other end of the push rod (15) is fixedly provided with a driving column (17), the circumferential outer surface of the rotating shaft close to the top end is fixedly provided with a driving disc (19), the lower surface of the driving disc (19) is provided with a cam driving groove (20), the driving column (17) is slidably provided with the inner wall of the cam driving groove (20), and the cam driving groove (20) is alternately formed by four convex grooves and four grooves.
3. The continuous biochip detection device according to claim 2, wherein the air outlet end of the compression box (13) penetrates through the inner wall of the dust hood (6) and is communicated with the inside of the dust hood, a unidirectional air inlet valve (16) is fixedly arranged on the outer surface of one side of the compression plate (14), an air filter core is arranged at the air inlet end of the unidirectional air inlet valve (16), a unidirectional air outlet valve (18) is arranged on the outer surface of one side of the dust hood (6) opposite to the compression box (13), and the air outlet end of the compression box (13) is arranged below the rotating plate (12).
4. The biochip continuous detection apparatus according to claim 1, wherein a plurality of fixed blocks (31) are fixedly installed on the circumferential outer surface of the turntable (2), a driven gear (32) is fixedly installed on the outer surface of one end of the turntable (12) penetrating through the fixed blocks (31), a fixed shaft is fixedly installed on the outer surface of one side of the fixed blocks (31), a sector gear (33) is rotatably installed on the circumferential outer surface of the fixed shaft, the sector gear (33) is meshed with the driven gear (32), an eccentric block is fixedly installed on the outer surface of the sector gear (33), and a slide column (35) is fixedly installed on the outer surface of the other end of the eccentric block.
5. The continuous biochip detecting device according to claim 4, characterized in that the inner wall of the C-shaped frame (5) is fixedly provided with a driving ring (7), the upper surface of the driving ring (7) is provided with a protrusion (701), the protrusion (701) is arranged on the upper surface of the driving ring (7) close to the dust cover (3), the sliding column (35) abuts against the upper surface of the driving ring (7), one end of the fixing shaft penetrates through the outer surface of the sector gear (33) and is sleeved with a torsion spring (34), one end of the torsion spring (34) is fixedly connected with the circumferential outer surface of the fixing shaft, and the other end of the torsion spring (34) is fixedly connected with the outer surface of the sector gear (33).
6. The continuous biochip detecting device according to claim 5, wherein the rotating plate (12) is provided with a mounting sink groove (21) on the outer surface of one side of the biochip, two L-shaped clamping rods (23) are symmetrically rotatably mounted on the inner wall of the mounting sink groove (21), two clamping columns (26) are fixedly mounted on the outer surfaces of the other ends of the L-shaped clamping rods (23) close to the sliding columns (35), annular clamping grooves are formed in the circumferential outer surfaces of the clamping columns (26), the biochip is arranged between the inner walls of the annular clamping grooves, a sliding groove (2701) is formed in the inner wall of the mounting sink groove (21), a sliding block (27) is slidably mounted on the inner wall of the sliding groove (2701), a moving plate is fixedly mounted on the top end of the sliding block (27), two guide grooves (29) are symmetrically formed in the outer surfaces of the moving plate, guide columns (28) are fixedly mounted on the outer surfaces of the other ends of the L-shaped clamping rods (23), and the inner walls of the guide columns (28) and the guide grooves (29) are slidably mounted, and the outer surfaces of the rotating plate (12) far from the driven gear (32) are provided with a stop block (22).
7. The continuous biochip detecting device according to claim 6, wherein a slide bar (24) is fixedly installed on the outer surface of one side of the slide block (27) close to the driven gear (32), a blocking head (30) is fixedly installed on the other end of the slide bar (24) penetrating through the end face of the rotating plate (12) close to one end of the driven gear (32), the blocking head (30) is arranged below the driving ring (7), a bump (702) is fixedly installed on the outer surface of one side of the driving ring (7) opposite to the dust hood (6), the blocking head (30) is abutted against the outer surface of the bump (702), a spring (25) is sleeved on the outer surface of the slide bar (24), and the spring (25) is arranged between the slide block (27) and the inner wall of the slide groove (2701) close to the driven gear (32).
8. The continuous biochip detecting device according to claim 6, wherein the bottom end of the rotating shaft penetrates through the lower surface of the base (1) and is fixedly provided with a driven sheave (11), the lower surface of the base (1) is rotatably provided with a driving plate (10), the driving plate (10) is meshed with the driven sheave (11), the lower surface of the base (1) is fixedly provided with a housing (8), the lower surface of the housing (8) is fixedly provided with a driving motor (9), the output end of the driving motor (9) penetrates through the outer surface of the housing (8) and is fixedly provided with four radial grooves in a fixed manner with the rotation center of the driving plate (10), and the circumferential direction of the outer surface of the driven sheave (11) is equidistantly provided with four radial grooves.
CN202510345906.5A 2025-03-24 2025-03-24 Continuous biochip detection device Active CN119873418B (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000039047A (en) * 1998-12-10 2000-07-05 조순복 Continuous automatic tapping device of reinforced plate of oil filter for vehicle
US20190244837A1 (en) * 2011-09-22 2019-08-08 Acm Research (Shanghai) Inc. Methods and apparatus for cleaning flip chip assemblies
CN212190382U (en) * 2020-03-04 2020-12-22 深圳橙子自动化有限公司 Feeding dust removal device and equipment
CN216483178U (en) * 2021-10-29 2022-05-10 上海纬朗光电科技有限公司 A visual inspection structure of a linear camera light source
CN218239859U (en) * 2022-07-22 2023-01-06 江苏汇丰薄膜有限公司 Film processing flaw check out test set
CN117381580A (en) * 2023-11-14 2024-01-12 成都理工大学 An integrated equipment for surface grinding and testing of hardware for high-altitude UHV substation equipment

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000039047A (en) * 1998-12-10 2000-07-05 조순복 Continuous automatic tapping device of reinforced plate of oil filter for vehicle
US20190244837A1 (en) * 2011-09-22 2019-08-08 Acm Research (Shanghai) Inc. Methods and apparatus for cleaning flip chip assemblies
CN212190382U (en) * 2020-03-04 2020-12-22 深圳橙子自动化有限公司 Feeding dust removal device and equipment
CN216483178U (en) * 2021-10-29 2022-05-10 上海纬朗光电科技有限公司 A visual inspection structure of a linear camera light source
CN218239859U (en) * 2022-07-22 2023-01-06 江苏汇丰薄膜有限公司 Film processing flaw check out test set
CN117381580A (en) * 2023-11-14 2024-01-12 成都理工大学 An integrated equipment for surface grinding and testing of hardware for high-altitude UHV substation equipment

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