CN119258871B - Double-shaft stirring mixer for pharmaceutical grade liquid medicine - Google Patents

Double-shaft stirring mixer for pharmaceutical grade liquid medicine

Info

Publication number
CN119258871B
CN119258871B CN202411820641.1A CN202411820641A CN119258871B CN 119258871 B CN119258871 B CN 119258871B CN 202411820641 A CN202411820641 A CN 202411820641A CN 119258871 B CN119258871 B CN 119258871B
Authority
CN
China
Prior art keywords
mixing
stirring
shaft
adjusting support
fixed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202411820641.1A
Other languages
Chinese (zh)
Other versions
CN119258871A (en
Inventor
张天明
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Xihong Biomedical Co ltd
Original Assignee
Jiangsu Xihong Biomedical Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Xihong Biomedical Co ltd filed Critical Jiangsu Xihong Biomedical Co ltd
Priority to CN202411820641.1A priority Critical patent/CN119258871B/en
Publication of CN119258871A publication Critical patent/CN119258871A/en
Application granted granted Critical
Publication of CN119258871B publication Critical patent/CN119258871B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/82—Combinations of dissimilar mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/443—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a superposed additional movement other than oscillation, vibration or shaking
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/449—Stirrers constructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/453—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements
    • B01F33/4532—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements using a bearing, tube, opening or gap for internally supporting the stirring element
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/10—Maintenance of mixers
    • B01F35/12—Maintenance of mixers using mechanical means
    • B01F35/121—Maintenance of mixers using mechanical means using a brush for cleaning out rests of products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/33—Transmissions; Means for modifying the speed or direction of rotation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/33—Transmissions; Means for modifying the speed or direction of rotation
    • B01F35/332—Transmissions; Means for modifying the speed or direction of rotation alternately changing the direction of rotation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B01F35/41—Mounting or supporting stirrer shafts or stirrer units on receptacles
    • B01F35/412—Mounting or supporting stirrer shafts or stirrer units on receptacles by supporting both extremities of the shaft
    • B01F35/4121—Mounting or supporting stirrer shafts or stirrer units on receptacles by supporting both extremities of the shaft at the top and at the bottom of the receptacle, e.g. for performing a conical orbital movement about a vertical axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B01F35/43—Supporting receptacles on frames or stands
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/45—Closures or doors specially adapted for mixing receptacles; Operating mechanisms therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/7547—Discharge mechanisms characterised by the means for discharging the components from the mixer using valves, gates, orifices or openings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22—Mixing of ingredients for pharmaceutical or medical compositions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Accessories For Mixers (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)

Abstract

The invention discloses a double-shaft stirring mixer for medical-grade liquid medicines, and relates to the technical field of medicine production. The invention combines two swingable mixing stirring shafts with the ultrasonic generator embedded in the stirring blade to enhance the mixing effect on the macroscopic and microscopic levels. The swing design of (mixing) shaft makes stirring paddle can with more liquid contact, improves stirring homogeneity. The cavitation effect of ultrasonic wave further promotes the refinement and dispersion of particles in the liquid, ensures the efficient mixing of medicines, is particularly suitable for medical-grade liquid medicines with high requirement on uniformity, controls the discharging process through an electric cylinder, and when the mixing is completed, the sealing plug is automatically pulled away, so that the mixed liquid is discharged through a funnel quickly, and residues are prevented from blocking a pipeline. The design not only improves the discharging efficiency, but also ensures the cleaning of the discharging pipeline, avoids the problems of shutdown and difficult cleaning caused by pipeline blockage in the traditional equipment, and is particularly suitable for medical factories with high-efficiency production requirements.

Description

Double-shaft stirring mixer for pharmaceutical grade liquid medicine
Technical Field
The invention relates to the technical field of medicine production, in particular to a double-shaft stirring mixer for medical-grade liquid medicines.
Background
Most of common pharmaceutical-grade liquid medicine stirring equipment in the current market adopts a single-shaft stirring structure, the fixed position and the rotating speed of a stirring blade cannot be flexibly adjusted, and uneven mixing of medicine liquid is easily caused. In addition, traditional agitated vessel generally lacks efficient discharge system, and liquid remains inside the equipment, leads to the discharge not thoroughly, has increased the waste and the clean degree of difficulty in the production process. Especially in the clean link, traditional equipment usually needs manual disassembly and flushing, and is low in efficiency and easy to risk cross contamination. Therefore, the prior art has significant shortcomings in terms of stirring uniformity, discharging efficiency and equipment cleaning.
Disclosure of Invention
In order to overcome the defects of the prior art, the technical scheme is that the double-shaft stirring mixer for medical-grade liquid medicines comprises a base barrel, a mixing bottom sealing plate is fixed at the top of the base barrel, a plurality of discharge ports are formed in the circumference of the mixing bottom sealing plate, a mixing stirring chamber is fixedly arranged on the mixing bottom sealing plate, the mixing stirring chamber is used for containing medicine liquids to be mixed, the discharge ports are used for discharging the mixed medicine liquids, a blocking sealing plug is hermetically inserted into each discharge port, all the blocking sealing plugs are fixed on a funnel, the funnel is used for guiding all the discharged medicine liquids into a discharge pipe, two mixing stirring shafts are rotatably arranged in the mixing stirring chamber, a plurality of stirring paddles are fixed on each mixing stirring shaft, each mixing stirring shaft can swing mutually and are used for changing the stirring position of the stirring paddles in the mixing stirring chamber, and an ultrasonic generator is embedded in each stirring paddle.
Preferably, the funnel and all the blocking sealing plugs are in sliding sealing fit with the inner wall of the base barrel, the bottom of the funnel is fixedly provided with a discharge middle pipe, and the discharge middle pipe is in sliding sealing fit with the discharge pipe.
Preferably, the upper surface of the mixing bottom sealing plate is rotationally matched with two concentric arranged central dial plates and two concentric arranged edge dial plates, the lower surface of the mixing bottom sealing plate is rotationally matched with two concentric arranged active rotary magnetic disks and two concentric arranged intermediate driving fluted discs, the intermediate driving fluted discs and the central dial plates are fixedly and synchronously driven by a synchronous driving shaft, the synchronous driving shaft is rotationally and hermetically matched with the mixing bottom sealing plate, and the edge dial plates are in transmission fit with the active rotary magnetic disks by means of magnetic coupling.
Preferably, two of the mixing stirring shafts are arranged along the axial direction of the mixing stirring chamber, two symmetrically arranged driven mixing gears are rotatably arranged on the lower surface of the mixing bottom sealing plate and are in meshed transmission with the middle driving fluted disc, two universal joints are rotatably arranged on the upper surface of the mixing bottom sealing plate, the two universal joints are fixedly in transmission fit with the two driven mixing gears through rotating shafts, and the two mixing stirring shafts are in transmission fit with the two driven mixing gears through corresponding universal joints.
Preferably, the initiative is rotated and is cooperated through rotatory disk support fixed transmission between disk and the synchronous drive shaft, and synchronous drive shaft's bottom mounting has the integral key shaft, adopts the gliding mode cover of spline to be equipped with the cleaning brush fretwork frame on the integral key shaft, is fixed with a plurality of and funnel inner wall slip and rotatory complex cleaning brush on the cleaning brush fretwork frame, and wherein the rotatory cooperation between cleaning brush fretwork frame and the row material intermediate tube has seted up a plurality of through-holes on the cleaning brush fretwork frame for discharge medicine liquid, unable axial displacement between cleaning brush fretwork frame and the row material intermediate tube.
Preferably, two symmetrically arranged electric cylinders are fixedly arranged on the inner wall of the base barrel through an electric cylinder bracket, and the end parts of telescopic rods of the two electric cylinders are fixedly matched with the funnel.
Preferably, the top of mixing stirring room is fixed with the top and adjusts the backup pad, the circumference department of top regulation backup pad upper surface is fixed with annular electromagnet, be fixed with the top seal apron on the annular electromagnet, be fixed with between top seal apron and the top regulation backup pad and adjust the supporting ring, adjust the supporting frame that two symmetrical arrangement was installed through two parallel arrangement's regulation support slide bar slidable mounting on the supporting ring, two regulation supporting frames are close to the equal rotary fit of one end of mixing stirring axle and have the regulation movable slide block, it establishes on the mixing stirring axle that corresponds to adjust movable slide block slip cap.
Preferably, each adjusting support slide bar is sleeved with a reset spring in a surrounding mode, two ends of the reset spring are fixed with the adjusting support frame and the adjusting support ring, one end, far away from the adjusting support frame, of the adjusting support slide bar is fixed with a permanent magnet, and the permanent magnet is in magnetic fit with the annular electromagnet.
Preferably, the top sealing cover plate is fixedly provided with an overhead cover, the overhead cover is fixedly provided with a driving motor, the overhead cover is also provided with a plurality of feed inlets, and the output shaft of the driving motor and the central dial plate are fixedly transmitted through a main shaft.
Compared with the prior art, the invention has the following beneficial effects that (1) the mixing effect is enhanced at the macroscopic level and the microscopic level by combining the two swingable mixing stirring shafts and the ultrasonic generator embedded in the stirring blade. The swing design of the stirring shaft enables the stirring blade to be in contact with more liquid, and stirring uniformity is improved to the greatest extent. The invention is characterized in that (2) a plurality of discharge ports are provided with sealing plugs, the discharge process is controlled by an electric cylinder, and after the mixing is completed, the sealing plugs are automatically pulled away, so that the mixed liquid is discharged through a funnel quickly, and residues are prevented from blocking a pipeline. The design not only improves the discharging efficiency, but also ensures the cleaning of the discharging pipeline, avoids the problems of shutdown and difficult cleaning caused by pipeline blockage in the traditional equipment, and is particularly suitable for medical factories with high-efficiency production requirements; and (3) the hollow frame of the cleaning brush provided by the invention can automatically clean the inner wall of the funnel when the synchronous transmission shaft rotates, so that the manual cleaning process after the equipment is operated is reduced. This not only improves cleaning efficiency but also reduces the risk of cross-contamination.
Drawings
Fig. 1 is an overall external structural view of the present invention.
Fig. 2 is a schematic view of the structure of the electric cylinder of the invention.
FIG. 3 is a schematic diagram of the structure of FIG. 2A according to the present invention.
FIG. 4 is a schematic view of the internal structure of the mixing and stirring chamber of the present invention.
FIG. 5 is a schematic view of the structure of the funnel of the present invention.
FIG. 6 is a schematic view of the structure of the center dial plate of the present invention.
In the drawing, the device comprises a base barrel, a 102-discharging pipe, a 103-electric cylinder bracket, a 104-discharging middle pipe, a 105-electric cylinder, a 106-funnel, a 107-spline shaft, a 108-synchronous transmission shaft, a 109-cleaning brush, a 110-cleaning brush hollow frame, a 111-blocking sealing plug, a 112-discharging hole, a 113-driving rotary magnetic disk, a 114-rotating magnetic disk bracket, a 115-mixing bottom sealing plate, a 116-middle driving fluted disc, a 117-driven mixing gear, a 118-mixing stirring shaft, a 119-stirring blade, a 120-universal joint, a 121-center dial plate, a 122-edge dial plate, a 123-mixing stirring chamber, a 124-top adjusting supporting plate, a 125-adjusting supporting ring, a 126-adjusting supporting slide rod, a 127-adjusting supporting frame, a 128-adjusting movable slide block, a 129-resetting spring, a 130-permanent magnet block, a 131-top sealing cover plate, a 132-ring electromagnet, a 133-overhead cover, a 134-driving motor, a 135-feeding hole and a 136-spindle.
Detailed Description
The technical scheme of the invention is further described below by means of specific embodiments with reference to the accompanying drawings 1-6.
The invention provides a double-shaft stirring mixer for medical-grade liquid medicines, which comprises a base barrel 101, wherein a mixing bottom sealing plate 115 is fixed at the top of the base barrel 101, a plurality of discharge ports 112 are formed in the circumference of the mixing bottom sealing plate 115, a mixing stirring chamber 123 is fixedly arranged on the mixing bottom sealing plate 115, the mixing stirring chamber 123 is used for containing medicine liquids to be mixed, the discharge ports 112 are used for discharging the mixed medicine liquids, each discharge port 112 is internally provided with a sealing plug 111 in a sealing manner, all the sealing plugs 111 are fixed on a funnel 106, the funnel 106 is used for guiding all the discharged medicine liquids into a discharge pipe 102, two mixing stirring shafts 118 are rotatably arranged in the mixing stirring chamber 123, a plurality of stirring paddles 119 are fixed on each mixing stirring shaft 118, each mixing stirring shaft 118 can mutually swing and are used for changing the stirring position of the stirring paddles 119 in the mixing stirring chamber 123, and an ultrasonic generator is embedded in each stirring paddle 119. The funnel 106 and all the blocking sealing plugs 111 are in sliding sealing fit with the inner wall of the base barrel 101, the bottom of the funnel 106 is fixedly provided with a discharge middle pipe 104, and the discharge middle pipe 104 is in sliding sealing fit with the discharge pipe 102.
The upper surface of the mixing bottom sealing plate 115 is rotatably matched with two concentrically arranged central dial plates 121 and edge dial plates 122, the lower surface of the mixing bottom sealing plate 115 is rotatably matched with two concentrically arranged active rotary magnetic disks 113 and an intermediate driving fluted disc 116, wherein the intermediate driving fluted disc 116 and the central dial plates 121 are fixedly and synchronously driven by a synchronous transmission shaft 108, the synchronous transmission shaft 108 is in rotary sealing fit with the mixing bottom sealing plate 115, and the edge dial plates 122 are in transmission fit with the active rotary magnetic disks 113 in a magnetic coupling mode. The two mixing shafts 118 are arranged along the axial direction of the mixing chamber 123, two symmetrically arranged driven mixing gears 117 are rotatably arranged on the lower surface of the mixing bottom sealing plate 115, the two driven mixing gears 117 are in meshed transmission with the middle driving fluted disc 116, two universal joints 120 are rotatably arranged on the upper surface of the mixing bottom sealing plate 115, the two universal joints 120 are fixedly in transmission fit with the two driven mixing gears 117 through rotating shafts, and the two mixing shafts 118 are in transmission fit with the two driven mixing gears 117 through corresponding universal joints 120. The driving rotary magnetic disk 113 is fixedly matched with the synchronous transmission shaft 108 through a rotary magnetic disk support 114, a spline shaft 107 is fixed at the bottom end of the synchronous transmission shaft 108, a cleaning brush hollow frame 110 is sleeved on the spline shaft 107 in a spline sliding mode, a plurality of cleaning brushes 109 which are matched with the inner wall of the hopper 106 in a sliding and rotating mode are fixed on the cleaning brush hollow frame 110, the cleaning brush hollow frame 110 is matched with the discharge intermediate pipe 104 in a rotating mode, a plurality of through holes are formed in the cleaning brush hollow frame 110 and used for discharging medicine liquid, and the cleaning brush hollow frame 110 cannot axially displace with the discharge intermediate pipe 104. Two symmetrically arranged electric cylinders 105 are fixedly arranged on the inner wall of the base barrel 101 through an electric cylinder bracket 103, and the telescopic rod ends of the two electric cylinders 105 are fixedly matched with a funnel 106.
The top of mixing stirring room 123 is fixed with top regulation backup pad 124, the circumference department of top regulation backup pad 124 upper surface is fixed with annular electromagnet 132, be fixed with top seal apron 131 on the annular electromagnet 132, be fixed with between top seal apron 131 and the top regulation backup pad 124 and adjust support ring 125, adjust support ring 125 and go up through two parallel arrangement's regulation support slide bar 126 slidable mounting that correspond and have two symmetrical arrangement's regulation braced frame 127, two regulation braced frame 127 are close to the equal rotary fit of one end of mixing stirring axle 118 and have regulation movable slide 128, regulation movable slide 128 slip cap is established on corresponding mixing stirring axle 118. And a reset spring 129 is sleeved on each adjusting support slide bar 126 in a surrounding manner, two ends of the reset spring 129 are fixed with the adjusting support frame 127 and the adjusting support ring 125, a permanent magnet 130 is fixed at one end, far away from the adjusting support frame 127, of each adjusting support slide bar 126, and the permanent magnet 130 is magnetically matched with the annular electromagnet 132. An overhead cover 133 is fixedly mounted on the top sealing cover plate 131, a driving motor 134 is fixedly mounted on the overhead cover 133, a plurality of feed inlets 135 are also formed in the overhead cover 133, and an output shaft of the driving motor 134 and the center dial plate 121 are fixedly transmitted through a main shaft 136.
The medicine to be mixed is poured into a mixing and stirring chamber 123 through a feed inlet 135, then a driving motor 134 is started, an output shaft of the driving motor 134 drives a central stirring disc 121 to rotate through a main shaft 136, the central stirring disc 121 rotates and drives an intermediate driving fluted disc 116 and a rotating disc support 114 to rotate through a synchronous transmission shaft 108, the rotating disc support 114 drives an active rotating disc 113 to rotate, the active rotating disc 113 drives an edge stirring disc 122 to rotate through magnetic force, and at the moment, the rotation of the central stirring disc 121 and the edge stirring disc 122 drives medicine liquid in the mixing and stirring chamber 123 to rotate. Meanwhile, the rotation of the middle driving fluted disc 116 drives the two driven mixing gears 117 to rotate, the two driven mixing gears 117 drive the mixing stirring shaft 118 to rotate through the universal joint 120, the mixing stirring shaft 118 drives the stirring blade 119 to rotate, the stirring blade 119 rotates to drive the surrounding medicine liquid to rotate, and the center stirring disc 121 and the edge stirring disc 122 are matched to drive the medicine liquid to rotate, so that stirring of all medicines in the mixing stirring chamber 123 is realized. Meanwhile, in order to better enable the stirring blade 119 to be in contact with more medicine liquid, the mixing stirring shaft 118 can be driven to swing, so that the stirring blade 119 swings, and therefore the stirring blade 119 is in contact with more medicine liquid, specifically, only the annular electromagnet 132 is required to be controlled to generate magnetic force, the annular electromagnet 132 can repel or attract the permanent magnet 130, the permanent magnet 130 is driven to be away from or lean against the new annular electromagnet 132, the movement of the permanent magnet 130 can drive the adjusting support slide bar 126 to move, the adjusting support slide bar 126 can drive the adjusting support frame 127 to move, the adjusting support frame 127 can drive the adjusting movable slide block 128 to slide on the mixing stirring shaft 118, the top end of the mixing stirring shaft 118 swings at the moment, the position of the stirring blade 119 in the mixing stirring chamber 123 is changed, and the reset spring 129 can enable the mixing stirring shaft 118 to be restored to the vertical position when the annular electromagnet 132 loses magnetic force. While stirring the medicine liquid by the stirring blade 119, an ultrasonic generator inside the stirring blade 119 is started, and the mixing is enhanced at a microscopic level by the ultrasonic cavitation effect.
After the mixing is completed, the electric cylinder 105 is started, the telescopic rod of the electric cylinder 105 drives the funnel 106 to slide downwards on the inner wall of the base barrel 101, so that the blocking sealing plug 111 is pulled away from the discharge port 112, at the moment, the discharge port 112 is in an open state, liquid in the mixing and stirring chamber 123 enters the funnel 106 through the discharge port 112, then is discharged into the discharge pipe 102 through the discharge intermediate pipe 104, and the mixed medicine liquid is discharged to a designated position through the discharge pipe 102 for collecting treatment. If the whole equipment needs to be cleaned, only the medicine needs to be changed into water (proper cleaning liquid is selected according to actual conditions), wherein the spline shaft 107 drives the cleaning brush hollow frame 110 to rotate when the synchronous transmission shaft 108 rotates, the cleaning brush hollow frame 110 drives the cleaning brush 109 to rotate, and the cleaning brush 109 can clean residual liquid on the inner wall of the funnel 106 when rotating.

Claims (4)

1. The double-shaft stirring mixer for the pharmaceutical liquid medicine is characterized by comprising a base barrel (101), wherein a mixing bottom sealing plate (115) is fixed at the top of the base barrel (101), a plurality of discharge ports (112) are formed in the circumference of the mixing bottom sealing plate (115), a mixing stirring chamber (123) is fixedly arranged on the mixing bottom sealing plate (115), the mixing stirring chamber (123) is used for containing the pharmaceutical liquid to be mixed, the discharge ports (112) are used for discharging the pharmaceutical liquid after mixing, each discharge port (112) is internally and hermetically inserted with a blocking sealing plug (111), all the blocking sealing plugs (111) are fixed on a funnel (106), and the funnel (106) is used for guiding all the discharged pharmaceutical liquid into a discharge pipe (102);
Two mixing stirring shafts (118) are rotatably arranged in the mixing stirring chamber (123), a plurality of stirring paddles (119) are fixed on each mixing stirring shaft (118), each mixing stirring shaft (118) can swing mutually and is used for changing the stirring position of each stirring paddle (119) in the mixing stirring chamber (123), and an ultrasonic generator is embedded in each stirring paddle (119);
The two mixing stirring shafts (118) are arranged along the axial direction of the mixing stirring chamber (123), two symmetrically arranged driven mixing gears (117) are rotatably arranged on the lower surface of the mixing bottom sealing plate (115), the two driven mixing gears (117) are in meshed transmission with the middle driving fluted disc (116), two universal joints (120) are rotatably arranged on the upper surface of the mixing bottom sealing plate (115), the two universal joints (120) are fixedly in transmission fit with the two driven mixing gears (117) through rotating shafts, the two mixing stirring shafts (118) are in transmission fit with the two driven mixing gears (117) through corresponding universal joints (120), a reset spring (129) is sleeved on each adjusting support sliding rod (126), two ends of the reset spring (129) are fixed with the adjusting support frame (127) and the adjusting support ring (125), one end, far away from the adjusting support frame (127), of each adjusting support sliding rod (126) is fixedly provided with a permanent magnet (130), and the permanent magnet (130) is magnetically fit with the annular electromagnet (132);
The cleaning brush comprises a funnel (106) and all blocking sealing plugs (111) which are in sliding sealing fit with the inner wall of a base barrel (101), a discharge middle pipe (104) is fixed at the bottom of the funnel (106), the discharge middle pipe (104) is in sliding sealing fit with a discharge pipe (102), two concentrically arranged central stirring discs (121) and an edge stirring disc (122) are rotatably matched on the upper surface of a mixed bottom sealing plate (115), two concentrically arranged active rotating magnetic discs (113) and an intermediate driving fluted disc (116) are rotatably matched on the lower surface of the mixed bottom sealing plate (115), the intermediate driving fluted disc (116) and the central stirring disc (121) are fixedly and synchronously driven through a synchronous transmission shaft (108), the synchronous transmission shaft (108) is in rotary sealing fit with the mixed bottom sealing plate (115), the edge stirring disc (122) is fixedly and fixedly matched with the active rotating magnetic disc (113) through a rotary disc bracket (114), a spline shaft (107) is fixed at the bottom end of the synchronous transmission shaft (108), a hollow brush (110) is sleeved on the shaft (107) in a sliding manner, a plurality of hollow brushes (110) are rotatably matched with the inner wall (110), the cleaning brush hollow frame (110) is in rotary fit with the discharge intermediate pipe (104), a plurality of through holes are formed in the cleaning brush hollow frame (110) and are used for discharging medicine liquid, and the cleaning brush hollow frame (110) cannot axially move with the discharge intermediate pipe (104).
2. A dual-shaft stirring mixer for pharmaceutical grade liquid medicines according to claim 1 is characterized in that two symmetrically arranged electric cylinders (105) are fixedly arranged on the inner wall of a base barrel (101) through an electric cylinder bracket (103), and the telescopic rod ends of the two electric cylinders (105) are fixedly matched with a funnel (106).
3. A dual-shaft stirring mixer for pharmaceutical liquid medicines according to claim 2 is characterized in that a top adjusting support plate (124) is fixed at the top end of a mixing and stirring chamber (123), an annular electromagnet (132) is fixed at the circumference of the upper surface of the top adjusting support plate (124), a top sealing cover plate (131) is fixed on the annular electromagnet (132), an adjusting support ring (125) is fixed between the top sealing cover plate (131) and the top adjusting support plate (124), two symmetrically arranged adjusting support frames (127) are slidably arranged on the adjusting support ring (125) through two corresponding adjusting support sliding rods (126) which are arranged in parallel, one ends, close to a mixing and stirring shaft (118), of the two adjusting support frames (127) are respectively and rotatably matched with an adjusting movable sliding block (128), and the adjusting movable sliding blocks (128) are slidably sleeved on the corresponding mixing and stirring shaft (118).
4. A dual-shaft stirring mixer for pharmaceutical liquid medicines according to claim 3, wherein an overhead cover (133) is fixedly arranged on the top sealing cover plate (131), a driving motor (134) is fixedly arranged on the overhead cover (133), a plurality of feeding holes (135) are further formed in the overhead cover (133), and a main shaft (136) is fixedly arranged between an output shaft of the driving motor (134) and the central dial plate (121).
CN202411820641.1A 2024-12-11 2024-12-11 Double-shaft stirring mixer for pharmaceutical grade liquid medicine Active CN119258871B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112108044A (en) * 2020-09-23 2020-12-22 岳玺石 Food processing mixing stirring device
CN115634611A (en) * 2022-10-11 2023-01-24 华中科技大学同济医学院附属协和医院 Medical medicine mixing arrangement

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3329988A4 (en) * 2016-04-18 2019-07-31 Isel Co., Ltd AGITATOR, AGITATOR, AGITATOR METHOD, CELL CULTURE METHOD, REACTION STIMULATION METHOD, AND AGITATOR ASSEMBLY METHOD
CN220238410U (en) * 2023-06-09 2023-12-26 安徽安科恒益药业有限公司 High-precision medicament mixer
CN221890010U (en) * 2024-03-06 2024-10-25 青岛顺慧混凝土有限公司 Concrete aggregate breaker

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112108044A (en) * 2020-09-23 2020-12-22 岳玺石 Food processing mixing stirring device
CN115634611A (en) * 2022-10-11 2023-01-24 华中科技大学同济医学院附属协和医院 Medical medicine mixing arrangement

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