CN119043873A - Solid medicament check out test set - Google Patents
Solid medicament check out test set Download PDFInfo
- Publication number
- CN119043873A CN119043873A CN202411518632.7A CN202411518632A CN119043873A CN 119043873 A CN119043873 A CN 119043873A CN 202411518632 A CN202411518632 A CN 202411518632A CN 119043873 A CN119043873 A CN 119043873A
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- CN
- China
- Prior art keywords
- placing platform
- state
- space
- platform
- placement platform
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N3/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N3/02—Details
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B1/00—Cleaning by methods involving the use of tools
- B08B1/10—Cleaning by methods involving the use of tools characterised by the type of cleaning tool
- B08B1/16—Rigid blades, e.g. scrapers; Flexible blades, e.g. wipers
- B08B1/165—Scrapers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B1/00—Cleaning by methods involving the use of tools
- B08B1/20—Cleaning of moving articles, e.g. of moving webs or of objects on a conveyor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B5/00—Cleaning by methods involving the use of air flow or gas flow
- B08B5/02—Cleaning by the force of jets, e.g. blowing-out cavities
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N3/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N3/08—Investigating strength properties of solid materials by application of mechanical stress by applying steady tensile or compressive forces
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention is suitable for the field of detection equipment, and provides solid medicament detection equipment which comprises a placing platform and a pressurizing block, wherein a discharge hole is formed in a space to be detected, the placing platform can enter a discharge state from a working state, the placing platform is subjected to angle change around a certain preset axis towards the discharge hole so as to form a state that the position far away from the discharge hole is high and the position close to the discharge hole is low, the placing platform is provided with a side surface corresponding to the extrusion end surface of the pressurizing block, and a scraper for cleaning the extrusion end of the pressurizing block in a non-extrusion state is arranged on the side surface of the placing platform when the placing platform is subjected to state switching.
Description
Technical Field
The invention relates to the field of detection equipment, in particular to solid medicament detection equipment.
Background
The types of pharmaceutical agents can be mainly classified into liquid agents and solid agents according to the state, wherein the solid agents can be finely classified into powdery agents, hard tablet agents, capsule agents and the like. In the mass production process of each medicament, sampling detection is needed to ensure the quality of medicaments in the same batch. One of the sample tests performed on solid hard tablet formulations is the crush strength test to determine the hardness of the solid hard tablet.
Specifically, the tablet to be measured is placed in the middle part region to be measured, the two side extrusion parts move towards the middle part and apply pressure to the tablet, the compression degree of the tablet can change along with the change of the operation, the bearing force is unequal between 2000Pa and 20000Pa until the tablet is compressed and broken, the device stops pressurizing, and whether the bearing pressure value reaches the standard is recorded and judged.
In the testing process, after the single extrusion is finished, tablet residues adhere to the surface of the extrusion part (the tablet is locally pressed to increase the adhesive force of the tablet to the working surface of the extrusion part, the tablet is still locally adhered to the working surface of the extrusion part and cannot fall off along with the crushing of the tablet), and if the adhered tablet residues are contacted with the tablet to be tested (the tablet residues and the tablet to be tested are not the same sample) along with the next extrusion operation, the tablet residues can cause concentrated stress in the tablet to be tested when the tablet to be tested is subjected to the extrusion operation, so that the tablet to be tested is crushed without reaching the test pressure, and is marked as a poor sample, and detection errors are caused.
In summary, it is clear that the prior art has inconvenience and defects in practical use, so that improvement is needed.
Disclosure of Invention
In view of the above-mentioned drawbacks, an object of the present invention is to provide a solid medicament detection device, which can clean tablet residues disposed at the extrusion end of a pressurizing block by using a scraper disposed on a placement platform, and synchronously realize scraping work and air flow cleaning work by using angle switching in the discharging process of the placement platform, and has the advantages of high integration level, compact work, good cleaning effect and high cleaning efficiency.
In order to achieve the above purpose, the invention provides solid medicament detection equipment which comprises a placing platform arranged in a space to be detected and a pressurizing block arranged on at least one side of the space to be detected and moving along the direction of a working surface of the placing platform, wherein the space to be detected is provided with a discharge port, the placing platform can enter into a discharge state from a working state, the specific switching process is that the placing platform changes an angle around a certain preset axis towards the direction of the discharge port so as to form a state with a high position far from the discharge port and a low position close to the discharge port, the placing platform is provided with a side surface corresponding to the extruding end surface of the pressurizing block, and the side surface is provided with a scraper for cleaning the extruding end of the pressurizing block in a non-extruding state when the placing platform switches the state.
According to the solid medicament detection equipment provided by the invention, the placing platform in the working state is in a horizontal state.
According to the solid medicament detection equipment, the placement platform is installed in a space to be detected in an end hinged mode.
According to the solid medicament detection equipment, the placement platform is driven by the driving assembly to perform angle switching, the driving assembly comprises a driving space arranged below the placement platform, a rotating piece rotatably installed in the driving space, and a connecting piece for connecting the rotating piece and the placement platform, and one end of the connecting piece is eccentrically installed on the rotating piece, and the other end of the connecting piece is installed at a preset position of the placement platform.
According to the solid medicine agent detection device of the present invention, the rotating member is a disc or a cam structure and is driven to rotate by a driver.
According to the solid medicament detection equipment, the side face of the placement platform is provided with the mounting grooves for mounting the scrapers, the scrapers are provided with a plurality of groups and are arranged in the mounting grooves along the extending direction of the side face, and each scraper is mounted in the mounting groove through an elastic piece, so that the scrapers are stressed to stretch and retract along the opening direction of the mounting groove.
According to the solid medicament detection equipment, the side wall of the space to be detected is provided with the exhaust port facing the direction of the discharge port, and after the placing platform is reset after discharging is finished, the exhaust port releases the cleaning air flow.
The solid medicament detection equipment is characterized in that the air outlet is connected with an air supply assembly, the air supply assembly comprises a pressurizing piston arranged at the bottom of the placement platform, an elastic air storage piece communicated with the pressurizing piston and an air valve arranged at the air outlet, the pressurizing piston is of a deformable bag-shaped structure and is connected with the bottom surface of the placement platform and the side wall of the rack, and the elastic air storage piece is communicated with the air outlet.
The invention provides solid medicament detection equipment which comprises a placing platform arranged in a space to be detected and a pressurizing block arranged on at least one side of the space to be detected and moving along the direction of a working surface of the placing platform, wherein the space to be detected is provided with a discharge port, the placing platform can enter into a discharge state from a working state, the placing platform is subjected to angle change around a certain preset axis towards the direction of the discharge port to form a state with a high position far from the discharge port and a low position close to the discharge port, the placing platform is provided with a side surface corresponding to the extruding end surface of the pressurizing block, and a scraper for cleaning the extruding end of the pressurizing block in a non-extruding state is arranged on the side surface when the placing platform is subjected to state switching. The device can clean the tablet residues at the extrusion end of the pressurizing block by using the scraper arranged on the placing platform, and synchronously realize scraping work and air flow cleaning work by using the angle switching of the discharging process of the placing platform, and has the advantages of high equipment integration level, compact work, good cleaning effect and high cleaning efficiency.
Drawings
FIG. 1 is an overall schematic of the present invention;
FIG. 2 is a schematic view of the internal structure at section A of FIG. 1;
FIG. 3 is a schematic diagram of the operation of the pressurizing block of FIG. 2;
FIG. 4 is a schematic view of the placement platform of FIG. 2 in a discharge position;
FIG. 5 is a schematic view of the installation of a doctor blade;
FIG. 6 is a schematic view of the structure of the doctor blade;
FIG. 7 is a schematic view of the drive assembly and air supply assembly of the placement platform;
In the figure, 00-space to be measured, 01-discharge opening, 02-upper cover, 03-frame, 1-placing platform, 2-pressurizing block, 3-rotating piece, 4-connecting piece, 5-exhaust port, 6-scraper, 61-oblique cutting face, 7-mounting groove, 8-elastic piece, 81-pressurizing piston, 82-elastic gas storage piece, 83-air valve.
Detailed Description
For the purpose of making apparent the objects, technical solutions and advantages of the present invention, the present invention will be further described in detail with reference to the accompanying drawings and examples, it being understood that the specific examples described herein are for illustration only and are not intended to limit the present invention.
Referring to fig. 1 and 2, the present application provides a solid medicine testing apparatus, which includes a placement platform 1 placed in a space to be tested 00, and a pressing block 2 disposed on at least one side of the space to be tested 00 and moving along a direction of a working surface (an upper surface of the placement platform 1) of the placement platform 1, wherein the pressing block 2 is slidably mounted on a frame 03 and is driven by a moving driving member (typically, an electric cylinder or an air cylinder mounted with a pressure sensor) to move (the moving driving member of the pressing block 2 is not an existing structure and is not described in detail in the text and the drawing), the moving pressing block 2 presses the space to be tested (the volume of the space to be tested is reduced), in this embodiment, the pressing block 2 is disposed with two pressing blocks and is disposed on two sides of the space to be tested 00, respectively, and the two pressing blocks 2 press the space to be tested in a centered manner during the pressing.
Referring to fig. 2 and 3, during testing, a tablet is placed on the placement platform 1, then, two pressing blocks 2 move centering and apply pressure to the tablet, the value of the pressure sensor is gradually increased, when the tablet is instantaneously broken (the value of the pressure sensor is instantaneously reduced), the pressing blocks 2 stop moving, then move and reset, and finally, the value before the instantaneous reduction of the pressure sensor is recorded.
The frame 03 is further hinged with an upper cover 02 for fastening and sealing the space 00 to be tested, and the space 00 to be tested is fastened and sealed by the upper cover in the testing process, so that the safety of the working environment of the equipment is improved.
The space to be tested 00 is provided with a discharge hole 01, and after the test is finished, the broken tablets are discharged from the discharge hole.
Referring to fig. 1 and 3, the placement platform 1 may enter a discharging state from a working state, and specifically, the switching process is that the placement platform 1 makes an angle change around a certain predetermined axis toward the direction of the discharge port 01, so as to form a state where the position far away from the discharge port 01 is high and the position near the discharge port 01 is low, in this state, the broken tablet slides out of the apparatus from the discharge port 01 along an inclined plane formed by the placement platform 1 under the action of self weight. The placing platform 1 in the working state is in a horizontal state, and the inclination angle of the placing platform 1 in the discharging state is 45-60 degrees.
Referring to fig. 7, the driving assembly includes a driving space disposed below the placement platform 1, a rotating member 3 rotatably mounted in the driving space, and a connecting member 4 connecting the rotating member 3 and the placement platform 1, wherein the rotating member 3 is in a disc or cam structure and is driven by a driver (only by a motor) to rotate, and the connecting member 4 is only a connecting rod. One end of the connecting piece 4 is eccentrically arranged on the rotating piece 3, and the other end of the connecting piece is arranged at a preset position of the placing platform 1.
When the state of the placement platform 1 is driven to be switched, the driver drives the rotating piece 3 to rotate, and the eccentric connection point position is driven to continuously change when the rotating piece 3 rotates, so that the angle of the placement platform 1 is driven to be switched through the connecting piece 4.
Referring to fig. 4, 5 and 6, the placement platform 1 has a side corresponding to the extrusion end face of the pressing block 2, and the side is provided with a scraper 6 for cleaning the extrusion end of the pressing block 2 in a non-extrusion state when the placement platform 1 is in state switching, and during the angle switching of the placement platform 1, residues of tablets adhered to the extrusion end face of the pressing block 2 can be scraped off by the scraper 6. Specifically, in order to optimize the scraping effect, the side surface of the placement platform 1 is provided with a mounting groove 7 for mounting the scrapers 6, the scrapers 6 are provided with a plurality of groups and are arranged in the mounting groove 7 along the extending direction of the side surface, and the length of each group of scrapers 6 accounts for about 1/7~1/5 of the mounting groove 7.
Each scraper 6 is installed in the installation groove 7 through an elastic piece 8 (a spring can be used), and the elastic piece 8 enables the scraper 6 to be stressed and move telescopically along the opening direction of the installation groove 7. On the one hand, the elastic piece 8 applies pressure to the scraper 6 in the direction of the extrusion end face of the pressurizing block 2 to optimize the scraping effect, and on the other hand, the scraper 6 can be contained in the mounting groove 7 to ensure the normal operation of the angle switching work of the placing platform 1 (without causing interference on the work).
The two sides of the edge of each scraper blade 6 are provided with inclined cutting edges 61, and the inclined cutting edges 61 can be matched with the angle switching of the placement platform 1, and the side wall of the frame 03 is used for extruding the scraper blades 6 to retract into the mounting grooves 7.
Preferably, the side wall of the space to be measured 00 is provided with the air outlet 5 facing the direction of the discharge outlet 01, and after the placing platform 1 is reset after being discharged, the air outlet 5 releases cleaning air flow which can clean the tablet residues scraped by the scraper 6 and the tablet residues remained on the placing platform 1.
Referring to fig. 7, the air outlet 5 is connected to an air supply assembly, the air supply assembly includes a pressurizing piston 81 disposed at the bottom of the placement platform 1, an elastic air storage member 82 (an elastic air bag made of rubber) in communication with the pressurizing piston 81, and an air valve 83 mounted at the air outlet 5, the pressurizing piston 81 is in a deformable bag-like structure (the same can be made of soft plastic or rubber), and is connected to the bottom surface of the placement platform 1 and the side wall of the frame 03 (to form an air extrusion space with a predetermined volume), and the elastic air storage member 82 is in communication with the air outlet 5.
In this embodiment, the air valve 83 is turned on and off by the change of the inclination angle of the placement platform 1 (an angle sensor is installed at the hinge of the placement platform 1, and the electronic control unit of the air valve 83 is controlled by the sensor to achieve this function). Specifically, when the placement platform 1 is turned up to about 10 ° (specifically, one end far away from the hinge edge is higher than the air outlet 5), the air valve 83 is opened, at this time, the inside of the pressurizing piston 81 is negative pressure, and the external air flow enters the pressurizing piston 81 or the elastic air storage member 82 from the air outlet 5, so that the tablet residues can be effectively prevented from being sucked to the air outlet 5 in the above working state.
When the placement platform 1 is turned up to the maximum angle, the air valve 83 enters a closed state;
after the discharging is finished, the space in the pressurizing piston 81 is pressurized and the elastic air storage piece 82 is expanded (the internal air pressure is increased) in the process of resetting the placing platform 1 to the horizontal state, when the placing platform 1 is reset to the horizontal state, the air valve 83 is opened, the air flow in the elastic air storage piece 82 is released, and the air flow in the state can be instantly released under the action of the air pressure, so that the cleaning effect is optimized.
Of course, the present invention is capable of other various embodiments and its several details are capable of modification and variation in light of the present invention, as will be apparent to those skilled in the art, without departing from the spirit and scope of the invention as defined in the appended claims.
Claims (8)
1. The solid medicament detection equipment is characterized by comprising a placement platform arranged in a space to be detected and a pressurizing block which is arranged on at least one side of the space to be detected and moves along the direction of a working surface of the placement platform;
the space to be tested is provided with a discharge hole;
the placing platform can enter a discharging state from a working state, and the specific switching process is that the placing platform changes angles around a certain preset axis towards the direction of the discharging port so as to form a state that the position far from the discharging port is high and the position close to the discharging port is low;
The placing platform is provided with a side surface corresponding to the extrusion end surface of the pressurizing block, and the side surface is provided with a scraper for cleaning the extrusion end of the pressurizing block in a non-extrusion state when the placing platform is subjected to state switching.
2. The solid medicament detection device according to claim 1, wherein the placement platform in an operative state is in a horizontal state.
3. The solid dosage testing device of claim 1, wherein the placement platform is mounted end-on in the space to be tested.
4. The solid medicine testing device according to claim 1, wherein the placement platform is driven by a driving assembly to perform an angle switching operation;
The driving assembly comprises a driving space arranged below the placing platform, a rotating piece rotatably arranged in the driving space, and a connecting piece for connecting the rotating piece and the placing platform;
One end of the connecting piece is eccentrically arranged on the rotating piece, and the other end of the connecting piece is arranged at a preset position of the placing platform.
5. The solid medicine testing device according to claim 4, wherein the rotating member is a disc or a cam structure and is driven to rotate by a driver.
6. The solid medicament detection device according to claim 1, wherein the side surface of the placement platform is provided with a mounting groove for mounting the scrapers, and the scrapers are provided with a plurality of groups and are arranged in the mounting groove along the side surface extending direction;
Each scraper is arranged in the mounting groove through an elastic piece, so that the scraper is stressed to stretch and retract along the opening direction of the mounting groove.
7. The solid medicine testing apparatus according to claim 1, wherein an exhaust port facing the discharge port is provided on a side wall of the space to be tested;
and after the placing platform is reset after discharging, the exhaust port releases the cleaning airflow.
8. The solid dosage testing device of claim 7, wherein the vent is connected to an air supply assembly;
The air supply assembly comprises a pressurizing piston arranged at the bottom of the placing platform, an elastic air storage piece communicated with the pressurizing piston and an air valve arranged at the air outlet;
the pressurizing piston is of a deformable bag-shaped structure and is connected with the bottom surface of the placing platform and the side wall of the rack;
The elastic gas storage piece is communicated with the gas outlet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411518632.7A CN119043873B (en) | 2024-10-29 | 2024-10-29 | Solid medicament check out test set |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411518632.7A CN119043873B (en) | 2024-10-29 | 2024-10-29 | Solid medicament check out test set |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN119043873A true CN119043873A (en) | 2024-11-29 |
| CN119043873B CN119043873B (en) | 2025-01-24 |
Family
ID=93575941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202411518632.7A Active CN119043873B (en) | 2024-10-29 | 2024-10-29 | Solid medicament check out test set |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN119043873B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4542646A (en) * | 1984-10-12 | 1985-09-24 | The Upjohn Company | Tablet hardness tester |
| CN211602763U (en) * | 2019-12-26 | 2020-09-29 | 天津市精创科仪科技有限公司 | A tablet hardness tester |
| CN212483229U (en) * | 2020-07-17 | 2021-02-05 | 河南盛世汉唐生物科技有限公司 | Multifunctional hardness tester device for laboratory drug research and development |
| CN221860187U (en) * | 2023-12-19 | 2024-10-18 | 上海微巨实业有限公司 | A tadalafil finished product detection device |
-
2024
- 2024-10-29 CN CN202411518632.7A patent/CN119043873B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4542646A (en) * | 1984-10-12 | 1985-09-24 | The Upjohn Company | Tablet hardness tester |
| CN211602763U (en) * | 2019-12-26 | 2020-09-29 | 天津市精创科仪科技有限公司 | A tablet hardness tester |
| CN212483229U (en) * | 2020-07-17 | 2021-02-05 | 河南盛世汉唐生物科技有限公司 | Multifunctional hardness tester device for laboratory drug research and development |
| CN221860187U (en) * | 2023-12-19 | 2024-10-18 | 上海微巨实业有限公司 | A tadalafil finished product detection device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN119043873B (en) | 2025-01-24 |
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