CN118201590A - Cosmetic product - Google Patents
Cosmetic product Download PDFInfo
- Publication number
- CN118201590A CN118201590A CN202280073325.5A CN202280073325A CN118201590A CN 118201590 A CN118201590 A CN 118201590A CN 202280073325 A CN202280073325 A CN 202280073325A CN 118201590 A CN118201590 A CN 118201590A
- Authority
- CN
- China
- Prior art keywords
- cosmetic
- component
- formula
- carbon atoms
- oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000002537 cosmetic Substances 0.000 title claims abstract description 70
- -1 cyclic carboxamide Chemical class 0.000 claims abstract description 32
- 150000003839 salts Chemical class 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000004721 Polyphenylene oxide Substances 0.000 claims abstract description 12
- 229920000570 polyether Polymers 0.000 claims abstract description 12
- 229920002635 polyurethane Polymers 0.000 claims abstract description 11
- 239000004814 polyurethane Substances 0.000 claims abstract description 11
- 125000004432 carbon atom Chemical group C* 0.000 claims description 21
- 125000000217 alkyl group Chemical group 0.000 claims description 12
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 11
- 150000002430 hydrocarbons Chemical group 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 8
- 125000002947 alkylene group Chemical group 0.000 claims description 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 6
- 229920001577 copolymer Polymers 0.000 claims description 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 4
- HBAIZGPCSAAFSU-UHFFFAOYSA-N 1-(2-hydroxyethyl)imidazolidin-2-one Chemical compound OCCN1CCNC1=O HBAIZGPCSAAFSU-UHFFFAOYSA-N 0.000 claims description 3
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims description 3
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims description 3
- 239000003921 oil Substances 0.000 description 30
- 235000019198 oils Nutrition 0.000 description 30
- 239000004166 Lanolin Substances 0.000 description 7
- 235000019388 lanolin Nutrition 0.000 description 7
- 229940039717 lanolin Drugs 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- 229920001296 polysiloxane Polymers 0.000 description 7
- 239000001993 wax Substances 0.000 description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 239000002562 thickening agent Substances 0.000 description 5
- DSSYKIVIOFKYAU-OIBJUYFYSA-N (S)-camphor Chemical compound C1C[C@]2(C)C(=O)C[C@H]1C2(C)C DSSYKIVIOFKYAU-OIBJUYFYSA-N 0.000 description 4
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 4
- 230000004927 fusion Effects 0.000 description 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 235000015112 vegetable and seed oil Nutrition 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 3
- 239000006096 absorbing agent Substances 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 239000004359 castor oil Substances 0.000 description 3
- 235000019438 castor oil Nutrition 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- SHZIWNPUGXLXDT-UHFFFAOYSA-N ethyl hexanoate Chemical compound CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 description 3
- 239000000194 fatty acid Substances 0.000 description 3
- 229930195729 fatty acid Natural products 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 3
- 239000003760 tallow Substances 0.000 description 3
- 239000006097 ultraviolet radiation absorber Substances 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 2
- 239000005711 Benzoic acid Substances 0.000 description 2
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 description 2
- 239000004215 Carbon black (E152) Substances 0.000 description 2
- 235000017788 Cydonia oblonga Nutrition 0.000 description 2
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 description 2
- 244000020551 Helianthus annuus Species 0.000 description 2
- 235000003222 Helianthus annuus Nutrition 0.000 description 2
- CMBYOWLFQAFZCP-UHFFFAOYSA-N Hexyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCCCCC CMBYOWLFQAFZCP-UHFFFAOYSA-N 0.000 description 2
- 229920000161 Locust bean gum Polymers 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 2
- QMGVPVSNSZLJIA-UHFFFAOYSA-N Nux Vomica Natural products C1C2C3C4N(C=5C6=CC=CC=5)C(=O)CC3OCC=C2CN2C1C46CC2 QMGVPVSNSZLJIA-UHFFFAOYSA-N 0.000 description 2
- 240000007817 Olea europaea Species 0.000 description 2
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 description 2
- 229920002125 Sokalan® Polymers 0.000 description 2
- 244000107975 Strychnos nux-vomica Species 0.000 description 2
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- 229940009868 aluminum magnesium silicate Drugs 0.000 description 2
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 2
- RWZYAGGXGHYGMB-UHFFFAOYSA-N anthranilic acid Chemical compound NC1=CC=CC=C1C(O)=O RWZYAGGXGHYGMB-UHFFFAOYSA-N 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- 239000003125 aqueous solvent Substances 0.000 description 2
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical compound CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 description 2
- 235000010233 benzoic acid Nutrition 0.000 description 2
- 239000012964 benzotriazole Substances 0.000 description 2
- 239000010495 camellia oil Substances 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 235000019864 coconut oil Nutrition 0.000 description 2
- 239000003240 coconut oil Substances 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 229920006037 cross link polymer Polymers 0.000 description 2
- GPLRAVKSCUXZTP-UHFFFAOYSA-N diglycerol Chemical compound OCC(O)COCC(O)CO GPLRAVKSCUXZTP-UHFFFAOYSA-N 0.000 description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- MMXKVMNBHPAILY-UHFFFAOYSA-N ethyl laurate Chemical compound CCCCCCCCCCCC(=O)OCC MMXKVMNBHPAILY-UHFFFAOYSA-N 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- BIHCCQRFXYRMHE-UHFFFAOYSA-N heptan-2-yl undecanoate Chemical compound CCCCCCCCCCC(=O)OC(C)CCCCC BIHCCQRFXYRMHE-UHFFFAOYSA-N 0.000 description 2
- 229940100463 hexyl laurate Drugs 0.000 description 2
- 239000003906 humectant Substances 0.000 description 2
- 229930195733 hydrocarbon Natural products 0.000 description 2
- BJRNKVDFDLYUGJ-RMPHRYRLSA-N hydroquinone O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-RMPHRYRLSA-N 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 description 2
- 235000010420 locust bean gum Nutrition 0.000 description 2
- 239000000711 locust bean gum Substances 0.000 description 2
- 159000000003 magnesium salts Chemical class 0.000 description 2
- VAMXMNNIEUEQDV-UHFFFAOYSA-N methyl anthranilate Chemical compound COC(=O)C1=CC=CC=C1N VAMXMNNIEUEQDV-UHFFFAOYSA-N 0.000 description 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 2
- 235000019271 petrolatum Nutrition 0.000 description 2
- 239000008177 pharmaceutical agent Substances 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- XOJVVFBFDXDTEG-UHFFFAOYSA-N pristane Chemical compound CC(C)CCCC(C)CCCC(C)CCCC(C)C XOJVVFBFDXDTEG-UHFFFAOYSA-N 0.000 description 2
- 229960004889 salicylic acid Drugs 0.000 description 2
- 239000012176 shellac wax Substances 0.000 description 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 2
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 description 2
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 description 1
- DSEKYWAQQVUQTP-XEWMWGOFSA-N (2r,4r,4as,6as,6as,6br,8ar,12ar,14as,14bs)-2-hydroxy-4,4a,6a,6b,8a,11,11,14a-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-1h-picen-3-one Chemical compound C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3C[C@@H](O)C(=O)[C@@H]1C DSEKYWAQQVUQTP-XEWMWGOFSA-N 0.000 description 1
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical class C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 description 1
- BJDAUCLANVMIOB-UHFFFAOYSA-N (3-decanoyloxy-2,2-dimethylpropyl) decanoate Chemical compound CCCCCCCCCC(=O)OCC(C)(C)COC(=O)CCCCCCCCC BJDAUCLANVMIOB-UHFFFAOYSA-N 0.000 description 1
- RUHCWQAFCGVQJX-RVWHZBQESA-N (3s,8s,9s,10r,13r,14s,17r)-3-hydroxy-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-1-one Chemical compound C1C=C2C[C@H](O)CC(=O)[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 RUHCWQAFCGVQJX-RVWHZBQESA-N 0.000 description 1
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 description 1
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical class C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- RBNPOMFGQQGHHO-UHFFFAOYSA-N -2,3-Dihydroxypropanoic acid Natural products OCC(O)C(O)=O RBNPOMFGQQGHHO-UHFFFAOYSA-N 0.000 description 1
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 1
- QMMJWQMCMRUYTG-UHFFFAOYSA-N 1,2,4,5-tetrachloro-3-(trifluoromethyl)benzene Chemical compound FC(F)(F)C1=C(Cl)C(Cl)=CC(Cl)=C1Cl QMMJWQMCMRUYTG-UHFFFAOYSA-N 0.000 description 1
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 description 1
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- DHGBAFGZLVRESL-UHFFFAOYSA-N 14-methylpentadecyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC(C)C DHGBAFGZLVRESL-UHFFFAOYSA-N 0.000 description 1
- OUZOBPPZPCBJAR-UHFFFAOYSA-N 14-methylpentadecyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC(C)C OUZOBPPZPCBJAR-UHFFFAOYSA-N 0.000 description 1
- RKJGFHYCZPZJPE-UHFFFAOYSA-N 2,2-bis(16-methylheptadecanoyloxymethyl)butyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(CC)(COC(=O)CCCCCCCCCCCCCCC(C)C)COC(=O)CCCCCCCCCCCCCCC(C)C RKJGFHYCZPZJPE-UHFFFAOYSA-N 0.000 description 1
- XFOQWQKDSMIPHT-UHFFFAOYSA-N 2,3-dichloro-6-(trifluoromethyl)pyridine Chemical compound FC(F)(F)C1=CC=C(Cl)C(Cl)=N1 XFOQWQKDSMIPHT-UHFFFAOYSA-N 0.000 description 1
- XCQFTFZCTGZCNP-UHFFFAOYSA-N 2-(2-ethylhexanoyloxy)ethyl 2-ethylhexanoate Chemical compound CCCCC(CC)C(=O)OCCOC(=O)C(CC)CCCC XCQFTFZCTGZCNP-UHFFFAOYSA-N 0.000 description 1
- IYAZLDLPUNDVAG-UHFFFAOYSA-N 2-(benzotriazol-2-yl)-4-(2,4,4-trimethylpentan-2-yl)phenol Chemical compound CC(C)(C)CC(C)(C)C1=CC=C(O)C(N2N=C3C=CC=CC3=N2)=C1 IYAZLDLPUNDVAG-UHFFFAOYSA-N 0.000 description 1
- OBETXYAYXDNJHR-UHFFFAOYSA-N 2-Ethylhexanoic acid Chemical compound CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 1
- YKIBDQMASGIXFB-UHFFFAOYSA-N 2-ethylhexanoic acid;2-ethyl-2-(hydroxymethyl)propane-1,3-diol Chemical compound CCC(CO)(CO)CO.CCCCC(CC)C(O)=O.CCCCC(CC)C(O)=O.CCCCC(CC)C(O)=O YKIBDQMASGIXFB-UHFFFAOYSA-N 0.000 description 1
- SFAAOBGYWOUHLU-UHFFFAOYSA-N 2-ethylhexyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(CC)CCCC SFAAOBGYWOUHLU-UHFFFAOYSA-N 0.000 description 1
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- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 1
- DZKXJUASMGQEMA-UHFFFAOYSA-N tetradecyl tetradecanoate Chemical compound CCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCC DZKXJUASMGQEMA-UHFFFAOYSA-N 0.000 description 1
- AOBORMOPSGHCAX-DGHZZKTQSA-N tocofersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2O[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-DGHZZKTQSA-N 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 229960000401 tranexamic acid Drugs 0.000 description 1
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 description 1
- ICUTUKXCWQYESQ-UHFFFAOYSA-N triclocarban Chemical compound C1=CC(Cl)=CC=C1NC(=O)NC1=CC=C(Cl)C(Cl)=C1 ICUTUKXCWQYESQ-UHFFFAOYSA-N 0.000 description 1
- 229960001325 triclocarban Drugs 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- JMCRETWEZLOFQT-UHFFFAOYSA-M trimethyl(3-triethoxysilylpropyl)azanium;chloride Chemical compound [Cl-].CCO[Si](OCC)(OCC)CCC[N+](C)(C)C JMCRETWEZLOFQT-UHFFFAOYSA-M 0.000 description 1
- 229940118594 trimethylolpropane triisostearate Drugs 0.000 description 1
- 239000002383 tung oil Substances 0.000 description 1
- 239000004034 viscosity adjusting agent Substances 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000010497 wheat germ oil Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/87—Polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
[ Problem ] to provide a cosmetic having excellent feel in use. [ solution ] A cosmetic comprising: (A) a cyclic carboxamide derivative having a specific structure or a salt thereof, (B) a hydrophobically modified polyether polyurethane and (C) water.
Description
Technical Field
The present invention relates to a cosmetic composition comprising a cyclic carboxamide derivative having a specific structure or a salt thereof and a hydrophobically modified polyether polyurethane.
Background
Since hydrophobically modified polyether polyurethanes are known as viscosity modifiers (also referred to as associative thickeners) having little temperature dependence of viscosity, a unique film feel is obtained by blending the thickener, and therefore, cosmetics blended with hydrophobically modified polyether polyurethanes are commercially available in a large number. For example, a cosmetic product having improved feel in use, which contains a hydrophobically modified polyether polyurethane, nicotinamide and a specific surfactant, has been proposed (patent document 1). Such cosmetics are required to have a more excellent feel in use, and there is room for further improvement in feel in use.
On the other hand, it is known that a cyclic carboxamide derivative has an anti-wrinkle effect and a pigmentation-suppressing effect, and it is proposed to blend a cyclic carboxamide derivative into cosmetics and the like (patent document 2).
Prior art literature
Patent literature
Patent document 1: japanese patent laid-open No. 2021-172610
Patent document 2: international publication 2011/040496
Disclosure of Invention
According to the studies by the present inventors, it is found that when a cyclic carboxamide derivative is used in cosmetics, the fusion with the skin during application tends to be slow, and the mixture tends to be sticky after application. The present inventors have found that by using a cosmetic comprising a combination of a specific cyclic carboxamide derivative and a hydrophobically modified polyether polyurethane, surprisingly, skin-friendly feel, viscosity can be improved and at the same time more excellent feel in use can be achieved. The present invention is based on these findings.
According to the present invention, the following invention is provided.
[1] A cosmetic product comprising:
(A) A cyclic carboxamide derivative represented by formula (a) or a salt thereof;
(B) Hydrophobically modified polyether polyurethane; and
(C) The water is used as the water source,
(In the formula (a),
R a is a hydrocarbon group having 1 to 6 carbon atoms optionally substituted with a hydroxyl group, or a hydrogen atom,
X is-CH 2 -or-N (R 1) -, where R 1 is a C1-6 hydrocarbon group optionally substituted with a hydroxyl group, or is a hydrogen atom, and
N is an integer of 1 to 3. )
[2] The cosmetic according to [1], wherein in the formula (a) of the component (A),
R a is hydroxyalkyl of 1-3 carbon atoms,
X is-CH 2 -or-NH-, and
N is 1.
[3] The cosmetic according to [1] or [2], wherein the component (A) is 1- (2-hydroxyethyl) -2-imidazolidinone.
[4] The cosmetic according to any one of [1] to [3], wherein the blending amount of the component (A) is 0.1 to 5% by mass relative to the total amount of the cosmetic.
[5] The cosmetic according to any one of [1] to [4], wherein the component (B) is represented by the formula (B).
(In the formula (b),
R b1 is alkyl with 2-36 carbon atoms,
R b2 and R b4 are each independently a phenylethene or an alkylene group having 2 to 4 carbon atoms,
R b3 is an alkylene group having 1 to 10 carbon atoms optionally having a urethane bond,
R b5 is alkyl with 8-36 carbon atoms,
M is a number of 2 or more,
H is a number of 1 or more,
K is a number from 1 to 500, and
J is a number of 1 to 200. )
[6] The cosmetic according to any one of [1] to [5], wherein the component (B) is PEG-240/HDI copolymer bis-decyl tetradecyl polyether-20 ether.
[7] The cosmetic according to any one of [1] to [6], wherein the blending amount of the component (B) is 0.5 to 2.3% by mass relative to the total amount of the cosmetic.
[8] The cosmetic according to any one of [1] to [6], wherein the blending amount of the component (B) is 0.1 to 5% by mass relative to the total amount of the cosmetic.
[9] The cosmetic according to any one of [1] to [8], wherein the viscosity of the cosmetic is 2000 to 80000 mPas measured at 30 ℃ using a B-type rotational viscometer.
[10] The cosmetic according to any one of [1] to [9], which is a gel cosmetic.
According to the present invention, a cosmetic excellent in use feeling can be provided. In particular, the cream has good fusion with skin during application, is not sticky after application, and also gives mellow feeling.
Detailed Description
The present invention relates to a cosmetic composition comprising (A) a cyclic carboxamide derivative having a specific structure or a salt thereof, (B) a hydrophobically modified polyether polyurethane, and (C) water.
(A) Cyclic carboxamide derivative or salt thereof
The cosmetic of the present invention comprises a cyclic carboxamide derivative represented by the formula (a) or a salt thereof (hereinafter, sometimes referred to as component (a)), and other components are also similarly present.
In the formula (a), the amino acid sequence of the formula (a),
R a is a hydrocarbon group having 1 to 6 carbon atoms optionally substituted with a hydroxyl group, or a hydrogen atom,
X is-CH 2 -or-N (R 1) -, where R 1 is a C1-6 hydrocarbon group optionally substituted with a hydroxyl group, or is a hydrogen atom, and
N is an integer of 1 to 3.
The hydrocarbon group is not particularly limited, and may be, for example, an alkyl group, a cycloalkyl group, an alkenyl group, an alkynyl group, a cycloalkylalkyl group, a haloalkyl group, an alkoxyalkyl group, or an alkoxycarbonylalkyl group, and is preferably an alkyl group.
In a preferred embodiment, in the formula (a) of the component (A),
R a is hydroxyalkyl of 1-3 carbon atoms,
X is-CH 2 -or-NH-, and
N is 1.
Specific examples of the cyclic carboxamide derivative represented by formula (a) include the following.
(A) The most preferred ingredient is 1- (2-hydroxyethyl) -2-imidazolidinone.
(A) The component (a) may be a salt of a cyclic carboxamide derivative represented by the formula (a). The salt is not particularly limited as long as it is pharmaceutically acceptable, and may be an inorganic salt or an organic salt. Examples of the inorganic salts include hydrochloride, sulfate, phosphate, hydrobromide, sodium salt, potassium salt, magnesium salt, calcium salt, magnesium salt, and ammonium salt. Examples of the organic salt include acetate, lactate, maleate, fumarate, tartrate, methanesulfonate, p-toluenesulfonate, triethanolamine salt, and amino acid salt.
(A) The components may be blended in 1 or 2 or more. (A) The amount of the component (A) to be blended is preferably 0.1 to 5% by mass, more preferably 0.3 to 3% by mass, and still more preferably 1 to 2% by mass, based on the total amount of the cosmetic.
(B) Hydrophobically modified polyether polyurethanes
The cosmetic of the present invention comprises (B) a hydrophobically modified polyether polyurethane. (B) The components are also called associative thickeners and associative polymers.
In a preferred embodiment, the component (B) is represented by the formula (B).
In the formula (b), the amino acid sequence of the formula (b),
R b1 is an alkyl group having 2 to 36 carbon atoms, preferably an alkyl group having 2 to 4 carbon atoms.
R b2 and R b4 are each independently a phenylethene or an alkylene group having 2 to 4 carbon atoms, preferably an alkyl group having 2 to 4 carbon atoms.
R b3 is an alkylene group having 1 to 10 carbon atoms optionally having a urethane bond.
R b5 is an alkyl group having 8 to 36 carbon atoms, preferably an alkyl group having 12 to 24 carbon atoms.
M is a number of 2 or more, preferably 2.
H is a number of 1 or more, preferably 1.
K is a number of 1 to 500, preferably a number of 100 to 300.
J is a number of 1 to 200, preferably 10 to 100.
(B) The component is preferably PEG-240/HDI copolymer di-decyl tetradecyl polyether-20 ether. As a commercial product, for example, "ADEKA NOL GT-700" (manufactured by ADEKA Co., ltd.).
(B) The components may be blended in 1 or 2 or more. (B) The blending amount of the component is preferably 0.5 to 2.3% by mass, more preferably 1 to 1.8% by mass, based on the total amount of the cosmetic. Within this range, the unique film feel of component (B) can be further obtained. In the present specification, the film feel means: when applied to the skin, the soft coating film gently covers the skin to protect the touch.
(C) Water and its preparation method
The cosmetic of the present invention comprises (C) water. As the water, water used in cosmetics, quasi drugs, and the like can be used, and purified water, ion-exchanged water, tap water, and the like can be used, for example.
The amount of water to be blended is preferably 40 to 98% by mass, more preferably 60 to 90% by mass, based on the total amount of the cosmetic composition of the present invention.
The cosmetic of the present invention may contain other optional ingredients within a range that does not impair the effects of the present invention. Examples of other optional components include an aqueous solvent, a thickener (excluding component (B)), a humectant, an oil component, an ultraviolet absorber, a pharmaceutical agent, a chelating agent, a preservative, an antioxidant, a powder, a perfume, a colorant, a coloring agent, and the like, and can be suitably blended depending on the form and use of the cosmetic.
Examples of the aqueous solvent include lower alcohols such as ethanol, 1-propanol, 2-propanol, isobutanol, and t-butanol.
Examples of the thickener include acacia, carrageenan, karaya, tragacanth, carob gum, quince seed (quince), casein, dextrin, gelatin, sodium pectate, sodium alginate, methyl cellulose, ethyl cellulose, CMC, hydroxyethyl cellulose, hydroxypropyl cellulose, PVA, PVM, PVP, sodium polyacrylate, carboxyvinyl polymer (carbomer), dimethylacrylamide/sodium acryloyldimethyltaurate cross-linked polymer, acrylamide/ammonium VP copolymer, acrylamide dimethyltaurate/behenate-25 methacrylate cross-linked polymer, sodium acrylate/sodium acryloyldimethyltaurate copolymer, locust bean gum, guar gum, acid bean gum, dialkyl dimethyl ammonium cellulose sulfate, xanthan gum, aluminum magnesium silicate, bentonite, hectorite, aluminum magnesium silicate (VEEGUM), laponite, silicic anhydride, and the like.
Examples of the humectant include polyethylene glycol, propylene glycol, dipropylene glycol (DPG), glycerin, 1, 3-butanediol, chondroitin sulfate, hyaluronic acid, glycosaminoglycan sulfate, caronic acid, atelocollagen, cholesterol hydroxystearate, sodium lactate, bile acid salt, dl-pyrrolidone carboxylate, alkylene oxide derivative, short chain soluble collagen, diglycerol (EO) PO adduct, and the like. In the present specification, EO represents ethylene oxide, and PO represents propylene oxide.
The oil component is not particularly limited, and various kinds of oil components widely used in cosmetics, whether solid oil components or liquid oil components, may be blended.
The solid oil component is an oil component which is usually used in cosmetics and is solid or semisolid at room temperature. Examples of such oil components include solid oils such as cocoa butter, coconut oil, horse oil, hydrogenated coconut oil, palm oil, tallow, sheep oil, hardened tallow, palm kernel oil, lard, bovine bone oil, nux-vomica oil, hardened oil, tallow, nux-vomica oil, hydrogenated castor oil, and the like; waxes such as beeswax, candelilla wax, cotton wax, carnauba wax, bayberry wax, shellac wax, spermaceti wax, montan wax, rice husk wax, lanolin, kapok wax, acetylated lanolin, sugarcane wax, isopropyl lanolate, hexyl laurate, hydrogenated lanolin, jojoba wax, hard lanolin, shellac wax, POE lanolin alcohol ether, POE lanolin alcohol acetate, POE cholesterol ether, POE hydrogenated lanolin alcohol ether; hydrocarbon waxes such as polyethylene wax, paraffin wax, ceresin, petrolatum, microcrystalline wax, lunacera, etc.; fatty acid glycerol ethers such as monostearyl glycerol ether (batyl alcohol); fatty acid glycerides such as acetylglyceride and triglyceride (2-heptylundecanoate), and 1 or 2 or more of these may be used in combination.
Liquid oil refers to oil that is liquid at room temperature, which is commonly used in cosmetics. Examples of such oil include liquid oils such as avocado oil, evening primrose oil, camellia seed oil, turtle oil, macadamia rima (MACADAMIA INTEGRIFOLIA) seed oil, sunflower (HELIANTHUS ANNUUS) seed oil, sweet almond (PRUNUS AMYGDALUSDULCIS) oil, corn oil, mink oil, olive (OLEA EUROPAEA) fruit oil, rapeseed oil, egg oil, sesame oil, peach kernel oil, wheat germ oil, camellia oil, castor oil, linseed oil, safflower oil, cottonseed oil, perilla oil, soybean oil, peanut oil, tea seed oil, torreya oil, rice bran oil, jatropha oil, japan tung oil, jojoba seed oil, and germ oil; cetyl octanoate, ethyl cetyl 2-acetate, cetyl dimethyloctanoate, ethyl laurate, hexyl laurate, isopropyl myristate, 2-hexyldecyl myristate, myristyl myristate, octyldodecyl myristate, isopropyl palmitate, 2-ethylhexyl palmitate, isocetyl palmitate, 2-heptylundecyl palmitate, butyl stearate, isocetyl isostearate, decyl oleate, dodecyl oleate, oil oleate, lactic myristate, lactic cetyl lactate, diisostearyl malate, cholesterol 12-hydroxystearate, methyl castor oil fatty acid, 2-ethylhexyl succinate, and ester oils such as diisobutyl adipate, 2-hexyldecyl adipate, di (heptyl undecyl) adipate, diisopropyl sebacate, di (2-ethylhexyl) sebacate, ethylene glycol bis (2-ethylhexanoate), neopentyl glycol dicaprate, neopentyl glycol di (ethylhexanoate), acetylglyceride, di (2-heptyl undecanoate), trioctanoate, tri (2-ethylhexanoate), trimyristate, triisopalmitate, tri (2-heptyl undecanoate), trimethylolpropane tri (2-ethylhexanoate), trimethylolpropane triisostearate, pentaerythritol tetraoctanoate, pentaerythritol tetra-2-ethylhexanoate, and the like; hydrocarbon oils such as liquid paraffin, squalene, pristane, polybutene, and the like; silicone oils such as chain polysiloxanes such as dimethylpolysiloxane, polymethylphenylsiloxane, diphenylpolysiloxane, cyclic polysiloxanes such as octamethyl cyclotetrasiloxane, cyclopentadimethicone, and dodecamethyl cyclosiloxane, and various modified polysiloxanes such as amino modified polysiloxanes, polyether modified polysiloxanes, alkyl modified polysiloxanes, and fluorine modified polysiloxanes, and 1 or 2 or more of these may be used in combination.
Examples of the ultraviolet absorber include benzoic acid-based ultraviolet absorbers such as p-aminobenzoic acid; an anthranilic acid-based ultraviolet absorber such as methyl anthranilate; salicylic acid ultraviolet absorbers such as octyl salicylate; cinnamic acid ultraviolet absorbers such as isopropyl p-methoxycinnamate and octyl p-methoxycinnamate; pyridazine derivatives such as dimorpholinopyridazinone; benzoyl methane derivatives such as 4-methoxy-4' -tert-butyldibenzoylmethane; camphor derivatives such as 3- (4' -methylbenzylidene) -D, l-camphor, 3-benzylidene-D, l-camphor and the like; benzotriazole derivatives such as 2,2' -hydroxy-5-methylphenyl benzotriazole, 2- (2 ' -hydroxy-5 ' -tert-octylphenyl) benzotriazole and 2- (2 ' -hydroxy-5 ' -methylphenyl benzotriazole, 2-phenyl-5-methylbenzoxazole, dibenzhydrazine, diphenylaminomethane, 5- (3, 3-dimethyl-2-norbornene) -3-pentan-2-one, and the like.
Examples of the pharmaceutical agents include ascorbic acid (vitamin C), tranexamic acid, kojic acid, ellagic acid, nicotinic acid, arbutin, alkoxysalicylic acid, glycyrrhizic acid, tocopherol, retinol, and salts or derivatives of these (for example, sodium L-ascorbate, magnesium L-ascorbate, L-ascorbyl glucoside, 2-O-ethyl-L-ascorbic acid, 3-O-ethyl-L-ascorbic acid, 4-methoxysalicylate, 4-methoxysalicylic acid potassium salt, dipotassium glycyrrhizinate, stearyl glycyrrhetinate, nicotinamide, tocopheryl acetate, retinol palmitate, and the like). In addition, various extracts and the like may be blended, but the cosmetic of the present invention also includes the following means: does not contain flavonoid-containing plant extract and humus extract.
Examples of the chelating agent include citramalic acid, matsutake acid, glyceric acid, shikimic acid, sabinol, gallic acid, tannic acid, caffeic acid, ethylenediamine tetraacetic acid, diethylenetriamine pentaacetic acid, phytic acid, polyphosphoric acid, metaphosphoric acid, and analogues, alkali metal salts, and carboxylic acid esters thereof.
Examples of the preservative include parabens such as methylparaben, ethylparaben and butylparaben, benzoic acid, salicylic acid, sorbic acid, parachlorometacresol, hexachlorophene, benzalkonium chloride, chlorhexidine, trichlorocarbanilide, photosensitizers, phenoxyethanol, and the like.
Examples of the antioxidant include α -tocopherol and carotenoid.
The cosmetic of the present invention can be widely applied to the following forms: basic cosmetics such as medicines, quasi-medicines (ointments, etc.), facial cleanser, astringent, emulsion, cream, gel, essence (skin-care liquid), dressing, facial mask, etc.; make-up cosmetics such as foundations and lipsticks; sun care commodities such as sunscreens; aromatic cosmetics; body cosmetics, and the like.
In a preferred embodiment, the composition is used as a skin cosmetic in view of the feel of use when applied to the skin. More preferably, the cosmetic of the present invention is a gel cosmetic.
The viscosity of the cosmetic of the present invention is preferably 2000 to 80000 mPas, more preferably 4000 to 20000 mPas, as measured at 30℃using a B-type rotational viscometer.
Examples
The present invention will be specifically described with reference to the following examples, but the present invention is not limited to these examples. The content is expressed as mass% relative to the total amount unless otherwise indicated.
Examples 1 to 5 and comparative examples 1 to 4
Cosmetics of examples 1 to 5 and comparative examples 1 to 4 were prepared by blending as shown in Table 1. The numerical values of the respective components in the table represent mass%.
The viscosity of the obtained cosmetics is shown in Table 1. The viscosity was measured using a type B viscometer (30 ℃). The viscosity of comparative example 1 was not measured because it was liquid, and was 1,000 mPas or less.
The cosmetics of examples 1 to 5 and comparative examples 2 to 4 were gel-like, and the cosmetic of comparative example 1 was liquid.
TABLE 1
The cosmetics prepared above were applied to the skin by 10 panelists 10, and evaluated for "presence or absence of stickiness after application", "merits of fusion during application", and "body feeling after application". Based on the evaluation of each panelist, a determination was made according to the following criteria. The results obtained are shown in Table 1.
[ Sticky Presence or not after application ]
A: more than 7 of the 10 panelists had responses that were not sticky.
B: more than 4 and less than 6 of the 10 panelists had no sticky responses.
C: more than 1 and less than 3 of the 10 panelists had no sticky responses.
D: all responses from 10 panelists were sticky.
[ Fusion in smearing ]
A: more than 7 of the 10 panellists fused well.
B: more than 4 and less than 6 of the 10 panellists fused well.
C: more than 1 and less than 3 of the 10 panelists fused well.
D: all responses of the 10 panelists fused poorly.
[ Mellow feeling after application ]
A: more than 7 of the 10 panelists had a mellow response.
B: more than 4 and less than 6 of the 10 panelists had a mellow feeling in response.
C: more than 1 and less than 3 of the 10 panelists had a mellow feeling in response.
D: all 10 panelists responded to the skin with poor body feeling.
Claims (10)
1. A cosmetic product comprising:
(A) A cyclic carboxamide derivative represented by formula (a) or a salt thereof;
(B) Hydrophobically modified polyether polyurethane; and
(C) The water is used as the water source,
In the formula (a), the amino acid sequence of the formula (a),
R a is a hydrocarbon group having 1 to 6 carbon atoms optionally substituted with a hydroxyl group, or a hydrogen atom,
X is-CH 2 -or-N (R 1) -, where R 1 is a C1-6 hydrocarbon group optionally substituted with a hydroxyl group, or is a hydrogen atom, and
N is an integer of 1 to 3.
2. The cosmetic according to claim 1, wherein in the formula (a) of the component (A),
R a is hydroxyalkyl of 1-3 carbon atoms,
X is-CH 2 -or-NH-, and
N is 1.
3. The cosmetic according to claim 1 or 2, wherein component (a) is 1- (2-hydroxyethyl) -2-imidazolidinone.
4. The cosmetic according to claim 1 or 2, wherein the component (a) is incorporated in an amount of 0.1 to 5% by mass based on the total amount of the cosmetic.
5. The cosmetic according to claim 1 or 2, wherein the component (B) is represented by the formula (B),
In the formula (b), the amino acid sequence of the formula (b),
R b1 is alkyl with 2-36 carbon atoms,
R b2 and R b4 are each independently a phenylethene or an alkylene group having 2 to 4 carbon atoms,
R b3 is an alkylene group having 1 to 10 carbon atoms optionally having a urethane bond,
R b5 is alkyl with 8-36 carbon atoms,
M is a number of 2 or more,
H is a number of 1 or more,
K is a number from 1 to 500, and
J is a number of 1 to 200.
6. The cosmetic according to claim 1 or2, wherein the component (B) is PEG-240/HDI copolymer bis-decyltetradecylether-20 ether.
7. The cosmetic according to claim 1 or 2, wherein the blending amount of the component (B) is 0.5 to 2.3% by mass relative to the total amount of the cosmetic.
8. The cosmetic according to claim 1 or 2, wherein the blending amount of the component (B) is 0.1 to 5% by mass relative to the total amount of the cosmetic.
9. The cosmetic according to claim 1 or 2, wherein the viscosity of the cosmetic is 2000 to 80000 mPa-s as measured at 30 ℃ using a B-type rotational viscometer.
10. The cosmetic according to claim 1 or 2, which is a gel cosmetic.
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| Application Number | Priority Date | Filing Date | Title |
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| JP2021-196753 | 2021-12-03 | ||
| JP2021196753 | 2021-12-03 | ||
| PCT/JP2022/042808 WO2023100682A1 (en) | 2021-12-03 | 2022-11-18 | Cosmetic |
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| CN118201590A true CN118201590A (en) | 2024-06-14 |
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| WO2011040496A1 (en) * | 2009-09-30 | 2011-04-07 | 株式会社資生堂 | Heparanase activity inhibitor |
| JP2012067024A (en) * | 2010-09-22 | 2012-04-05 | Shiseido Co Ltd | Skin care preparation for external use |
| JP2019014709A (en) * | 2017-07-07 | 2019-01-31 | ポーラ化成工業株式会社 | Skin care composition |
| JP2021172610A (en) * | 2020-04-24 | 2021-11-01 | 株式会社 資生堂 | Cosmetic |
-
2022
- 2022-11-18 WO PCT/JP2022/042808 patent/WO2023100682A1/en unknown
- 2022-11-18 CN CN202280073325.5A patent/CN118201590A/en active Pending
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| Publication number | Publication date |
|---|---|
| WO2023100682A1 (en) | 2023-06-08 |
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