CN118178562A - Jinguoyin oral liquid and preparation method thereof - Google Patents
Jinguoyin oral liquid and preparation method thereof Download PDFInfo
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Abstract
本发明属于中药领域,尤其是涉及一种金果饮口服液及其制备方法。制备所述金果饮口服液的原料包括按重量份数计算的以下组分:西青果50‑60份、罗汉果70‑76份、牛蒡子10‑16份、射干15‑20份、石斛10‑20份、百合8‑10份、陈皮8‑10份、蔗糖10‑14份、人参2‑4份、文竹3‑5份、知母3‑5份、芦荟1‑2份、葛粉8‑10份、胖大海5‑7份。所述金果饮口服液配伍合理,营养均衡,通过将西青果、牛蒡子、射干、石斛、陈皮结合在一起,能够达到清喉利咽、止咳化痰、缓解口臭等功效。本发明的口服液还包括蔗糖、人参、文竹、知母、芦荟、葛粉、胖大海,不仅增加营养成分,还能改善口味,适合更多人群服用。The invention belongs to the field of traditional Chinese medicine, and in particular, relates to a Jinguoyin oral liquid and a preparation method thereof. The raw materials for preparing the Jinguoyin oral liquid include the following components calculated by weight: 50-60 parts of Xiqingguo, 70-76 parts of Momordica grosvenori, 10-16 parts of Burdock, 15-20 parts of Belamcanda, 10-20 parts of Dendrobium, 8-10 parts of Lily, 8-10 parts of Tangerine Peel, 10-14 parts of Sucrose, 2-4 parts of Ginseng, 3-5 parts of Asparagus, 3-5 parts of Rhizoma Anemarrhenae, 1-2 parts of Aloe, 8-10 parts of Puerariae Powder, and 5-7 parts of Sterculia Sea. The Jinguoyin oral liquid has reasonable compatibility and balanced nutrition. By combining Xiqingguo, Burdock, Belamcanda, Dendrobium, and Tangerine Peel together, the effects of clearing throat and relieving phlegm, relieving bad breath, etc. can be achieved. The oral liquid of the present invention further comprises sucrose, ginseng, asparagus fern, rhizoma anemarrhenae, aloe vera, kudzu powder and sterculia lychnophora, which not only increases the nutritional components but also improves the taste and is suitable for more people to take.
Description
技术领域Technical Field
本发明涉及中药领域,尤其是涉及一种金果饮口服液及其制备方法。The invention relates to the field of traditional Chinese medicine, and in particular to a Jinguoyin oral liquid and a preparation method thereof.
背景技术Background technique
金果饮主要功效包括养阴生津,清热利咽,用于肺热阴伤所致的咽部红肿、咽痛、口干咽燥。将金果饮制成口服液,可以达到清喉利咽、止咳化痰、缓解口臭等功效。The main effects of Jinguoyin include nourishing yin and promoting body fluid, clearing away heat and relieving sore throat. It is used to treat redness and swelling of the throat, sore throat, dry mouth and throat caused by lung heat and yin damage. Jinguoyin can be made into an oral liquid to achieve the effects of clearing the throat, relieving cough and reducing phlegm, and relieving bad breath.
因此,提供一种金果饮口服液,具有重要意义。Therefore, providing a kind of Jinguoyin oral liquid is of great significance.
发明内容Summary of the invention
本发明的目的在于提供一种金果饮口服液及其制备方法,以克服解决现有技术中的问题。The purpose of the present invention is to provide a Jinguoyin oral liquid and a preparation method thereof, so as to overcome and solve the problems in the prior art.
为了实现上述目的,本发明实施例提供如下技术方案:In order to achieve the above objectives, the embodiments of the present invention provide the following technical solutions:
根据本发明实施例的第一方面,提供一种金果饮口服液口服液,制备所述金果饮口服液的原料包括按重量份数计算的以下组分:西青果50-60份、罗汉果70-76份、牛蒡子10-16份、射干15-20份、石斛10-20份、百合8-10份、陈皮8-10份、蔗糖10-14份、人参2-4份、文竹3-5份、知母3-5份、芦荟1-2份、葛粉8-10份、胖大海5-7份。According to a first aspect of an embodiment of the present invention, a Jinguoyin oral liquid is provided. The raw materials for preparing the Jinguoyin oral liquid include the following components calculated by weight: 50-60 parts of western green fruit, 70-76 parts of monk fruit, 10-16 parts of burdock fruit, 15-20 parts of belamcanda chinensis, 10-20 parts of dendrobium, 8-10 parts of lily, 8-10 parts of tangerine peel, 10-14 parts of sucrose, 2-4 parts of ginseng, 3-5 parts of asparagus fern, 3-5 parts of anemarrhena asphodeloides, 1-2 parts of aloe, 8-10 parts of kudzu powder, and 5-7 parts of sterculia lychnophora.
进一步的,制备所述金果饮口服液的原料包括按重量份数计算的以下组分:西青果55份、罗汉果73份、牛蒡子13份、射干17.5份、石斛15份、百合9份、陈皮9份、蔗糖12份、人参3份、文竹4份、知母4份、芦荟1.5份、葛粉9份、胖大海6份。Furthermore, the raw materials for preparing the Jinguoyin oral liquid include the following components calculated by weight: 55 parts of western green fruit, 73 parts of monk fruit, 13 parts of burdock fruit, 17.5 parts of belamcanda chinensis, 15 parts of dendrobium, 9 parts of lily, 9 parts of tangerine peel, 12 parts of sucrose, 3 parts of ginseng, 4 parts of asparagus fern, 4 parts of anemarrhena asphodeloides, 1.5 parts of aloe, 9 parts of kudzu powder, and 6 parts of sterculia lychnophora.
进一步的,制备所述金果饮口服液的原料包括按重量份数计算的以下组分:西青果50份、罗汉果70份、牛蒡子10份、射干15份、石斛10份、百合8份、陈皮8份、蔗糖10份、人参2份、文竹3份、知母3份、芦荟1份、葛粉8份、胖大海5份。Furthermore, the raw materials for preparing the Jinguoyin oral liquid include the following components calculated by weight: 50 parts of western green fruit, 70 parts of monk fruit, 10 parts of burdock fruit, 15 parts of belamcanda chinensis, 10 parts of dendrobium, 8 parts of lily, 8 parts of tangerine peel, 10 parts of sucrose, 2 parts of ginseng, 3 parts of asparagus fern, 3 parts of anemarrhena, 1 part of aloe, 8 parts of kudzu powder, and 5 parts of sterculia lychnophora.
进一步的,制备所述金果饮口服液的原料包括按重量份数计算的以下组分:西青果50份、罗汉果70份、牛蒡子10份、射干15份、石斛10份、百合8份、陈皮8份、蔗糖10份、人参2份、文竹3份、知母3份、芦荟1份、葛粉8份、胖大海5份。Furthermore, the raw materials for preparing the Jinguoyin oral liquid include the following components calculated by weight: 50 parts of western green fruit, 70 parts of monk fruit, 10 parts of burdock fruit, 15 parts of belamcanda chinensis, 10 parts of dendrobium, 8 parts of lily, 8 parts of tangerine peel, 10 parts of sucrose, 2 parts of ginseng, 3 parts of asparagus fern, 3 parts of anemarrhena, 1 part of aloe, 8 parts of kudzu powder, and 5 parts of sterculia lychnophora.
根据本发明实施例的第二方面,提供一种金果饮口服液的制备方法,包括以下步骤:According to a second aspect of an embodiment of the present invention, there is provided a method for preparing Jinguoyin oral liquid, comprising the following steps:
S1、称取西青果、罗汉果、牛蒡子、射干、石斛、百合、陈皮作为原料;S1. Weigh citrus aurantium, monk fruit, burdock fruit, belamcanda chinensis, dendrobium officinale, lily bulb and tangerine peel as raw materials;
S2、将所述西青果、罗汉果、牛蒡子、射干、石斛、百合和陈皮煎煮后收集药液,将所述药液浓缩,获得浓缩物;S2, collecting the medicinal liquid after decocting the Xiqing fruit, Momordica grosvenori, Burdock fruit, Belamcanda chinensis, Dendrobium officinale, Lilium bulbiferum and Tangerine peel, and concentrating the medicinal liquid to obtain a concentrate;
S3、将人参、文竹、知母、芦荟、胖大海分别加乙醇回流提取,获得人参提取液、文竹提取液、知母提取液、芦荟提取液、胖大海提取液,将所述人参提取液、文竹提取液、知母提取液、芦荟提取液、胖大海提取液混合,灭菌后获得混合液;S3, adding ethanol to reflux extraction of ginseng, asparagus fern, anemarrhena asphodeloides, aloe vera, and Sterculia lychnophora, respectively, to obtain ginseng extract, asparagus fern extract, anemarrhena asphodeloides extract, aloe vera extract, and Sterculia lychnophora extract, and mixing the ginseng extract, asparagus fern extract, anemarrhena asphodeloides extract, aloe vera extract, and Sterculia lychnophora extract, and sterilizing to obtain a mixed solution;
S4、将所述浓缩物置于容器中,向所述容器中添加葛粉和蔗糖,再向容器中添加混合液和碱性溶液,期间施加超声波进行处理,所述浓缩物完全溶解后,获得所述金果饮口服液。S4, placing the concentrate in a container, adding kudzu powder and sucrose to the container, and then adding a mixed solution and an alkaline solution to the container, applying ultrasonic treatment during the process, and obtaining the Jinguoyin oral liquid after the concentrate is completely dissolved.
进一步的,步骤S2中,所述煎煮温度为85-95℃,煎煮时间80-110min。Furthermore, in step S2, the decoction temperature is 85-95°C, and the decoction time is 80-110 minutes.
进一步的,步骤S3中所述灭菌温度为85-90℃,灭菌时间为10-20min。Furthermore, in step S3, the sterilization temperature is 85-90° C., and the sterilization time is 10-20 min.
进一步的,步骤S4中,所述超声波的频率为20-80kHz。Furthermore, in step S4, the frequency of the ultrasonic wave is 20-80 kHz.
进一步的,步骤S4中,加入混合液后再添加碱性溶液,直至所述浓缩物溶解。Furthermore, in step S4, after adding the mixed solution, an alkaline solution is added until the concentrate is dissolved.
进一步的,制备所述葛粉的方法包括先将葛根清洗,之后进行粉碎,过35-60目筛,获得葛粉。Furthermore, the method for preparing the kudzu powder includes first washing the kudzu root, then crushing it, and passing it through a 35-60 mesh sieve to obtain the kudzu powder.
本发明中涉及的中药原料的药理功效如下:The pharmacological effects of the Chinese medicinal raw materials involved in the present invention are as follows:
西青果,苦、酸、涩,平,归肺、大肠经,治虚证白喉,喉炎,扁桃体炎,菌痢;罗汉果,味甘性凉,归肺、大肠经,有润肺止咳、生津止渴的功效、适用于肺热或肺燥咳嗽、百日咳及暑热伤津口渴等,此外还有润肠通便的功效;牛蒡子,辛、苦,寒,主治风热感冒,温病初起,麻疹不透,痈肿疮毒;射干,具有清热解毒,消痰,利咽的功效,可用于治疗扁桃腺炎及腰痛等症;石斛,性味甘淡微咸,寒,入胃、肺,肾经,主治生津益胃,清热养阴,治热病伤津,口干烦渴,病后虚热,阴伤目暗;百合,味甘,微寒。归心、肺经。具有养阴润肺,清心安神的功效,用于治疗阴虚燥咳,劳嗽咳血,虚烦惊悸,失眠多梦,精神恍惚;陈皮,性味:性温,味辛、味苦,入脾经、胃经、肺经;理气健脾,调中,燥湿,化痰,主治脾胃气滞之脘腹胀满或疼痛、消化不良,湿浊阻中之胸闷腹胀、纳呆便溏,痰湿壅肺之咳嗽气喘。用于胸脘胀满,食少吐泻,咳嗽痰多;人参,归肺、脾、心经,含有糖类、维生素、氨基酸等营养成分,可以促进气血的生成,具有补气生血的功效;文竹,味甘、微苦,性寒,有润肺止咳,凉血通淋的功效,主治阴虚肺燥、咳嗽、咯血、小便淋沥等病症;知母,性味苦,寒;归肺、胃、肾经,具有清热泻火,滋阴润燥的功效;芦荟,性味:苦,寒,杀菌、消炎、健胃下泄、强心活血、免疫和再生、抗肿瘤、抗衰老、解毒、镇痛等药理作用;葛粉,性凉,能清热解毒,对上火引起的便秘、咽喉肿痛、热咳有清解作用;胖大海,具有清热润肺、利咽消炎解毒的作用,主要用于肺热声哑、干咳无痰、咽喉干痛、头痛目赤等症状。Xiqingguo is bitter, sour, astringent, and flat. It is in the lung and large intestine meridians and can treat diphtheria, laryngitis, tonsillitis, and bacillary dysentery due to deficiency syndrome. Luohanguo is sweet and cool in nature. It is in the lung and large intestine meridians and has the effects of moistening the lungs and relieving cough, promoting fluid production and relieving thirst. It is suitable for cough caused by lung heat or dryness, whooping cough, and thirst caused by heat damage to body fluids. In addition, it has the effect of moistening the intestines and relieving constipation. Burdock seeds are pungent, bitter, and cold. They are mainly used to treat wind-heat colds, early stage of febrile diseases, measles, carbuncle, and sore. Belamcanda has the effects of clearing away heat and detoxifying, eliminating phlegm, and relieving sore throat. It can be used to treat tonsillitis and lumbago. Dendrobium is sweet, light, and slightly salty in nature and cold. It enters the stomach, lung, and kidney meridians. It is mainly used to promote fluid production and benefit the stomach, clear away heat and nourish yin, and treat heat damage to body fluids due to febrile diseases, dry mouth and thirst, deficiency heat after illness, and dark eyes caused by yin damage. Lily is sweet and slightly cold. It is in the heart and lung meridians. It has the effects of nourishing yin and moistening the lungs, clearing the heart and calming the mind. It is used to treat yin deficiency and dry cough, fatigue cough and hemoptysis, restlessness and palpitations, insomnia and nightmares, and mental confusion. Tangerine peel, nature and flavor: warm in nature, pungent and bitter in taste, enters the spleen meridian, stomach meridian, and lung meridian; regulates qi and strengthens the spleen, regulates the middle, dries dampness, and resolves phlegm. It is mainly used to treat abdominal distension or pain caused by spleen and stomach qi stagnation, indigestion, chest tightness and abdominal distension caused by dampness and turbidity blocking the middle, poor appetite and loose stools, and cough and asthma caused by phlegm and dampness blocking the lungs. It is used for chest and abdominal distension, vomiting and diarrhea after poor appetite, and cough with excessive sputum; ginseng, which belongs to the lung, spleen, and heart meridians, contains nutrients such as sugars, vitamins, and amino acids, which can promote the formation of qi and blood, and has the effect of replenishing qi and generating blood; asparagus, which tastes sweet and slightly bitter, is cold in nature, has the effects of moistening the lungs and relieving coughs, cooling blood and relieving stranguria, and is mainly used to treat symptoms such as yin deficiency and lung dryness, cough, hemoptysis, and dribbling urine; anemarrhena, which is bitter and cold in nature; belongs to the lung, stomach, and kidney meridians, and has the effects of clearing away heat and purging fire, nourishing yin and moistening dryness; aloe, which is bitter and cold in nature, has the pharmacological effects of sterilization, anti-inflammatory, stomachic diarrhea, strengthening the heart and activating blood circulation, immunity and regeneration, anti-tumor, anti-aging, detoxification, and analgesia; kudzu powder, which is cool in nature, can clear away heat and detoxify, and has a clearing effect on constipation, sore throat, and hot cough caused by getting angry; Sterculia lychnophora, which has the effects of clearing heat and moistening the lungs, relieving sore throat, anti-inflammatory and detoxification, and is mainly used for symptoms such as lung heat and hoarseness, dry cough without sputum, dry and sore throat, headache and red eyes.
与现有技术相比,本发明的优点在于:Compared with the prior art, the advantages of the present invention are:
本发明提供一种金果饮口服液及其制备方法,所述金果饮口服液配伍合理,营养均衡,通过将西青果、牛蒡子、射干、石斛、陈皮结合在一起,能够达到清喉利咽、止咳化痰、缓解口臭等功效。此外,本发明的口服液还包括蔗糖、人参、文竹、知母、芦荟、葛粉、胖大海,不仅增加营养成分,还能改善口味,适合更多人群服用。The present invention provides a Jinguoyin oral liquid and a preparation method thereof. The Jinguoyin oral liquid has reasonable compatibility and balanced nutrition. By combining citrus aurantium, burdock fruit, belamcanda chinensis, dendrobium officinale and dried orange peel, the oral liquid can achieve the effects of clearing throat, relieving cough and reducing phlegm, and relieving bad breath. In addition, the oral liquid of the present invention also includes sucrose, ginseng, asparagus, rhizoma anemarrhenae, aloe, kudzu powder and sterculia lychnophora, which not only increases the nutritional components, but also improves the taste and is suitable for more people to take.
具体实施方式Detailed ways
下面将结合实施例对本发明的技术方案进行清楚、完整地描述,显然,所描述的实施例是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。The technical solution of the present invention will be clearly and completely described below in conjunction with the embodiments. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
本发明提供一种金果饮口服液口服液,制备所述金果饮口服液的原料包括按重量份数计算的以下组分:西青果50-60份、罗汉果70-76份、牛蒡子10-16份、射干15-20份、石斛10-20份、百合8-10份、陈皮8-10份、蔗糖10-14份、人参2-4份、文竹3-5份、知母3-5份、芦荟1-2份、葛粉8-10份、胖大海5-7份。The invention provides a Jinguoyin oral liquid. Raw materials for preparing the Jinguoyin oral liquid include the following components calculated by weight: 50-60 parts of citronella, 70-76 parts of monk fruit, 10-16 parts of burdock fruit, 15-20 parts of belamcanda chinensis, 10-20 parts of dendrobium, 8-10 parts of lily, 8-10 parts of tangerine peel, 10-14 parts of sucrose, 2-4 parts of ginseng, 3-5 parts of asparagus fern, 3-5 parts of rhizoma anemarrhenae, 1-2 parts of aloe, 8-10 parts of kudzu powder and 5-7 parts of sterculia lychnophora.
根据本发明实施例的第二方面,提供一种金果饮口服液的制备方法,包括以下步骤:According to a second aspect of an embodiment of the present invention, there is provided a method for preparing Jinguoyin oral liquid, comprising the following steps:
S1、称取西青果、罗汉果、牛蒡子、射干、石斛、百合、陈皮作为原料;S1. Weigh citrus aurantium, monk fruit, burdock fruit, belamcanda chinensis, dendrobium officinale, lily bulb and tangerine peel as raw materials;
S2、将所述西青果、罗汉果、牛蒡子、射干、石斛、百合和陈皮煎煮后收集药液,将所述药液浓缩,获得浓缩物;所述煎煮温度为85-95℃,煎煮时间80-110min;S2, collecting the medicinal liquid after decocting the Xiqing fruit, Momordica grosvenori, Burdock fruit, Belamcanda chinensis, Dendrobium officinale, Lilium bulbiferum and Tangerine peel, and concentrating the medicinal liquid to obtain a concentrate; the decocting temperature is 85-95° C., and the decocting time is 80-110 min;
S3、将人参、文竹、知母、芦荟、胖大海分别加乙醇回流提取,获得人参提取液、文竹提取液、知母提取液、芦荟提取液、胖大海提取液,将所述人参提取液、文竹提取液、知母提取液、芦荟提取液、胖大海提取液混合,灭菌后获得混合液;所述灭菌温度为85-90℃,灭菌时间为10-20min;S3, adding ethanol to reflux extraction of ginseng, asparagus fern, anemarrhena asphodeloides, aloe vera, and Sterculia lychnophora, respectively, to obtain ginseng extract, asparagus fern extract, anemarrhena asphodeloides extract, aloe vera extract, and Sterculia lychnophora extract, and mixing the ginseng extract, asparagus fern extract, anemarrhena asphodeloides extract, aloe vera extract, and Sterculia lychnophora extract, and sterilizing to obtain a mixed solution; the sterilization temperature is 85-90° C., and the sterilization time is 10-20 min;
S4、将所述浓缩物置于容器中,向所述容器中添加葛粉和蔗糖,再向容器中依次添加混合液和碱性溶液,直至所述浓缩物溶解,期间施加超声波进行处理,所述浓缩物完全溶解后,获得所述金果饮口服液;所述超声波的频率为20-80kHz。S4, placing the concentrate in a container, adding kudzu powder and sucrose to the container, and then sequentially adding a mixed solution and an alkaline solution to the container until the concentrate is dissolved, during which ultrasonic treatment is applied to obtain the Jinguoyin oral liquid after the concentrate is completely dissolved; the frequency of the ultrasonic wave is 20-80kHz.
在一些实施例中,制备所述葛粉的方法包括先将葛根清洗,之后进行粉碎,过35-60目筛,获得葛粉。In some embodiments, the method for preparing the kudzu powder comprises first washing the kudzu root, then crushing it, and passing it through a 35-60 mesh sieve to obtain the kudzu powder.
为更好的阐述本发明的技术方案,以下结合具体实施例进行详细论述。In order to better illustrate the technical solution of the present invention, it is discussed in detail below in conjunction with specific embodiments.
实施例1Example 1
本发明提供一种金果饮口服液口服液,制备所述金果饮口服液的原料包括按重量份数计算的以下组分:西青果55份、罗汉果73份、牛蒡子13份、射干17.5份、石斛15份、百合9份、陈皮9份、蔗糖12份、人参3份、文竹4份、知母4份、芦荟1.5份、葛粉9份、胖大海6份。The invention provides a Jinguoyin oral liquid. Raw materials for preparing the Jinguoyin oral liquid include the following components calculated by weight: 55 parts of citronella, 73 parts of monk fruit, 13 parts of burdock fruit, 17.5 parts of beam dry, 15 parts of dendrobium, 9 parts of lily, 9 parts of tangerine peel, 12 parts of sucrose, 3 parts of ginseng, 4 parts of asparagus fern, 4 parts of rhizoma anemarrhenae, 1.5 parts of aloe, 9 parts of kudzu powder and 6 parts of sterculia lychnophora.
根据本发明实施例的第二方面,提供一种金果饮口服液的制备方法,包括以下步骤:According to a second aspect of an embodiment of the present invention, there is provided a method for preparing Jinguoyin oral liquid, comprising the following steps:
S1、称取西青果、罗汉果、牛蒡子、射干、石斛、百合、陈皮作为原料;S1. Weigh citrus aurantium, monk fruit, burdock fruit, belamcanda chinensis, dendrobium officinale, lily bulb and tangerine peel as raw materials;
S2、将所述西青果、罗汉果、牛蒡子、射干、石斛、百合和陈皮煎煮后收集药液,将所述药液浓缩,获得浓缩物;所述煎煮温度为90℃,煎煮时间95min;S2, after decocting the Xiqingguo, Momordica grosvenori, Burdock fruit, Belamcanda chinensis, Dendrobium officinale, Lilium bulbiferum and Tangerine peel, collecting the medicinal liquid, and concentrating the medicinal liquid to obtain a concentrate; the decocting temperature is 90° C., and the decocting time is 95 min;
S3、将人参、文竹、知母、芦荟、胖大海分别加乙醇回流提取,获得人参提取液、文竹提取液、知母提取液、芦荟提取液、胖大海提取液,将所述人参提取液、文竹提取液、知母提取液、芦荟提取液、胖大海提取液混合,灭菌后获得混合液;所述灭菌温度为87.5℃,灭菌时间为15min;S3, adding ethanol to reflux extraction of ginseng, asparagus fern, anemarrhena asphodeloides, aloe vera, and Sterculia lychnophora, respectively, to obtain ginseng extract, asparagus fern extract, anemarrhena asphodeloides extract, aloe vera extract, and Sterculia lychnophora extract, and mixing the ginseng extract, asparagus fern extract, anemarrhena asphodeloides extract, aloe vera extract, and Sterculia lychnophora extract, and sterilizing to obtain a mixed solution; the sterilization temperature is 87.5° C., and the sterilization time is 15 min;
S4、将所述浓缩物置于容器中,向所述容器中添加葛粉和蔗糖,再向容器中依次添加混合液和碱性溶液,直至所述浓缩物溶解,期间施加超声波进行处理,所述浓缩物完全溶解后,获得所述金果饮口服液;所述超声波的频率为50kHz。S4, placing the concentrate in a container, adding kudzu powder and sucrose to the container, and then sequentially adding a mixed solution and an alkaline solution to the container until the concentrate is dissolved, during which ultrasonic treatment is applied to obtain the Jinguoyin oral liquid after the concentrate is completely dissolved; the frequency of the ultrasonic wave is 50 kHz.
在一些实施例中,制备所述葛粉的方法包括先将葛根清洗,之后进行粉碎,过47.5目筛,获得葛粉。In some embodiments, the method for preparing the kudzu powder comprises first washing the kudzu root, then crushing it, and passing it through a 47.5 mesh sieve to obtain the kudzu powder.
实施例2Example 2
本发明提供一种金果饮口服液口服液,制备所述金果饮口服液的原料包括按重量份数计算的以下组分:西青果50份、罗汉果70份、牛蒡子10份、射干15份、石斛10份、百合8份、陈皮8份、蔗糖10份、人参2份、文竹3份、知母3份、芦荟1份、葛粉8份、胖大海5份。The invention provides a Jinguoyin oral liquid. Raw materials for preparing the Jinguoyin oral liquid include the following components calculated by weight: 50 parts of citronella, 70 parts of monk fruit, 10 parts of burdock fruit, 15 parts of beam dry, 10 parts of dendrobium, 8 parts of lily, 8 parts of tangerine peel, 10 parts of sucrose, 2 parts of ginseng, 3 parts of asparagus fern, 3 parts of rhizoma anemarrhenae, 1 part of aloe, 8 parts of kudzu powder and 5 parts of sterculia lychnophora.
根据本发明实施例的第二方面,提供一种金果饮口服液的制备方法,包括以下步骤:According to a second aspect of an embodiment of the present invention, there is provided a method for preparing Jinguoyin oral liquid, comprising the following steps:
S1、称取西青果、罗汉果、牛蒡子、射干、石斛、百合、陈皮作为原料;S1. Weigh citrus aurantium, monk fruit, burdock fruit, belamcanda chinensis, dendrobium officinale, lily bulb and tangerine peel as raw materials;
S2、将所述西青果、罗汉果、牛蒡子、射干、石斛、百合和陈皮煎煮后收集药液,将所述药液浓缩,获得浓缩物;所述煎煮温度为85℃,煎煮时间80min;S2, after decocting the Xiqingguo, Momordica grosvenori, Burdock fruit, Belamcanda chinensis, Dendrobium officinale, Lilium bulbiferum and Tangerine peel, collecting the medicinal liquid, and concentrating the medicinal liquid to obtain a concentrate; the decoction temperature is 85° C., and the decoction time is 80 min;
S3、将人参、文竹、知母、芦荟、胖大海分别加乙醇回流提取,获得人参提取液、文竹提取液、知母提取液、芦荟提取液、胖大海提取液,将所述人参提取液、文竹提取液、知母提取液、芦荟提取液、胖大海提取液混合,灭菌后获得混合液;所述灭菌温度为85℃,灭菌时间为10min;S3, adding ethanol to reflux extraction of ginseng, asparagus fern, anemarrhena asphodeloides, aloe vera, and Sterculia lychnophora, respectively, to obtain ginseng extract, asparagus fern extract, anemarrhena asphodeloides extract, aloe vera extract, and Sterculia lychnophora extract, and mixing the ginseng extract, asparagus fern extract, anemarrhena asphodeloides extract, aloe vera extract, and Sterculia lychnophora extract, and sterilizing to obtain a mixed solution; the sterilization temperature is 85° C., and the sterilization time is 10 min;
S4、将所述浓缩物置于容器中,向所述容器中添加葛粉和蔗糖,再向容器中依次添加混合液和碱性溶液,直至所述浓缩物溶解,期间施加超声波进行处理,所述浓缩物完全溶解后,获得所述金果饮口服液;所述超声波的频率为20kHz。S4, placing the concentrate in a container, adding kudzu powder and sucrose to the container, and then sequentially adding a mixed solution and an alkaline solution to the container until the concentrate is dissolved, during which ultrasonic treatment is applied to obtain the Jinguoyin oral liquid after the concentrate is completely dissolved; the frequency of the ultrasonic wave is 20 kHz.
在一些实施例中,制备所述葛粉的方法包括先将葛根清洗,之后进行粉碎,过35目筛,获得葛粉。In some embodiments, the method for preparing the kudzu powder comprises first washing the kudzu root, then crushing it, and passing it through a 35-mesh sieve to obtain the kudzu powder.
实施例3Example 3
本发明提供一种金果饮口服液口服液,制备所述金果饮口服液的原料包括按重量份数计算的以下组分:西青果60份、罗汉果76份、牛蒡子16份、射干20份、石斛20份、百合10份、陈皮10份、蔗糖14份、人参4份、文竹5份、知母5份、芦荟2份、葛粉10份、胖大海7份。The invention provides a Jinguoyin oral liquid. Raw materials for preparing the Jinguoyin oral liquid include the following components calculated by weight: 60 parts of citronella, 76 parts of monk fruit, 16 parts of burdock fruit, 20 parts of beam dryness, 20 parts of dendrobium, 10 parts of lily, 10 parts of tangerine peel, 14 parts of sucrose, 4 parts of ginseng, 5 parts of asparagus fern, 5 parts of rhizoma anemarrhenae, 2 parts of aloe, 10 parts of kudzu powder and 7 parts of sterculia lychnophora.
根据本发明实施例的第二方面,提供一种金果饮口服液的制备方法,包括以下步骤:According to a second aspect of an embodiment of the present invention, there is provided a method for preparing Jinguoyin oral liquid, comprising the following steps:
S1、称取西青果、罗汉果、牛蒡子、射干、石斛、百合、陈皮作为原料;S1. Weigh citrus aurantium, monk fruit, burdock fruit, belamcanda chinensis, dendrobium officinale, lily bulb and tangerine peel as raw materials;
S2、将所述西青果、罗汉果、牛蒡子、射干、石斛、百合和陈皮煎煮后收集药液,将所述药液浓缩,获得浓缩物;所述煎煮温度为95℃,煎煮时间110min;S2, after decocting the Xiqing fruit, Momordica grosvenori, Burdock fruit, Belamcanda chinensis, Dendrobium officinale, Lilium bulbiferum and Tangerine peel, collecting the medicinal liquid, and concentrating the medicinal liquid to obtain a concentrate; the decocting temperature is 95° C., and the decocting time is 110 min;
S3、将人参、文竹、知母、芦荟、胖大海分别加乙醇回流提取,获得人参提取液、文竹提取液、知母提取液、芦荟提取液、胖大海提取液,将所述人参提取液、文竹提取液、知母提取液、芦荟提取液、胖大海提取液混合,灭菌后获得混合液;所述灭菌温度为90℃,灭菌时间为20min;S3, adding ethanol to reflux extraction of ginseng, asparagus fern, anemarrhena asphodeloides, aloe vera, and Sterculia lychnophora, respectively, to obtain ginseng extract, asparagus fern extract, anemarrhena asphodeloides extract, aloe vera extract, and Sterculia lychnophora extract, and mixing the ginseng extract, asparagus fern extract, anemarrhena asphodeloides extract, aloe vera extract, and Sterculia lychnophora extract, and sterilizing to obtain a mixed solution; the sterilization temperature is 90° C., and the sterilization time is 20 min;
S4、将所述浓缩物置于容器中,向所述容器中添加葛粉和蔗糖,再向容器中依次添加混合液和碱性溶液,直至所述浓缩物溶解,期间施加超声波进行处理,所述浓缩物完全溶解后,获得所述金果饮口服液;所述超声波的频率为80kHz。S4, placing the concentrate in a container, adding kudzu powder and sucrose to the container, and then sequentially adding a mixed solution and an alkaline solution to the container until the concentrate is dissolved, during which ultrasonic treatment is applied to obtain the Jinguoyin oral liquid after the concentrate is completely dissolved; the frequency of the ultrasonic wave is 80 kHz.
在一些实施例中,制备所述葛粉的方法包括先将葛根清洗,之后进行粉碎,过60目筛,获得葛粉。In some embodiments, the method for preparing the kudzu powder comprises first washing the kudzu root, then crushing it, and passing it through a 60-mesh sieve to obtain the kudzu powder.
实验1将实施例1-3的金果饮口服液作为实验组1-3,将不含射干和石斛的作为对照组1和对照组2;实验结果如下表1所示:Experiment 1: The Jinguoyin oral liquid of Examples 1-3 was used as experimental groups 1-3, and the oral liquid without Belamcanda chinensis and Dendrobium officinale was used as control group 1 and control group 2; the experimental results are shown in Table 1 below:
表1Table 1
最后应说明的是:以上各实施例仅用以说明本发明的技术方案,而非对其限制;尽管参照前述各实施例对本发明进行了详细的说明,本领域的普通技术人员应当理解:其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分或者全部技术特征进行等同替换;而这些修改或者替换,并不使相应技术方案的本质脱离本发明各实施例技术方案的范围。Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.
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