CN1177935C - 微生物生物转化法 - Google Patents
微生物生物转化法 Download PDFInfo
- Publication number
- CN1177935C CN1177935C CNB991183150A CN99118315A CN1177935C CN 1177935 C CN1177935 C CN 1177935C CN B991183150 A CNB991183150 A CN B991183150A CN 99118315 A CN99118315 A CN 99118315A CN 1177935 C CN1177935 C CN 1177935C
- Authority
- CN
- China
- Prior art keywords
- formula
- compound
- biotransformation
- culture
- microbial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9825598P | 1998-08-28 | 1998-08-28 | |
| US60/098,255 | 1998-08-28 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100459930A Division CN1271209C (zh) | 1998-08-28 | 1999-08-27 | 微生物生物转化法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1259577A CN1259577A (zh) | 2000-07-12 |
| CN1177935C true CN1177935C (zh) | 2004-12-01 |
Family
ID=22268411
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100459930A Expired - Fee Related CN1271209C (zh) | 1998-08-28 | 1999-08-27 | 微生物生物转化法 |
| CNB991183150A Expired - Fee Related CN1177935C (zh) | 1998-08-28 | 1999-08-27 | 微生物生物转化法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100459930A Expired - Fee Related CN1271209C (zh) | 1998-08-28 | 1999-08-27 | 微生物生物转化法 |
Country Status (25)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1156120B1 (en) * | 2000-05-08 | 2006-11-22 | Pfizer Products Inc. | Enzymatic resolution of selective estrogen receptor modulators |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5552412A (en) * | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
| US5618707A (en) * | 1996-01-04 | 1997-04-08 | Schering Corporation | Stereoselective microbial reduction of 5-fluorophenyl-5-oxo-pentanoic acid and a phenyloxazolidinone condensation product thereof |
-
1998
- 1998-08-27 ID IDP990811D patent/ID23459A/id unknown
-
1999
- 1999-08-24 TW TW088114475A patent/TWI225096B/zh not_active IP Right Cessation
- 1999-08-24 YU YU40599A patent/YU40599A/sh unknown
- 1999-08-25 DE DE69937662T patent/DE69937662T2/de not_active Expired - Fee Related
- 1999-08-25 EP EP99306750A patent/EP0989187B1/en not_active Expired - Lifetime
- 1999-08-25 DK DK99306750T patent/DK0989187T3/da active
- 1999-08-25 ES ES99306750T patent/ES2297913T3/es not_active Expired - Lifetime
- 1999-08-25 AT AT99306750T patent/ATE380251T1/de not_active IP Right Cessation
- 1999-08-25 PT PT99306750T patent/PT989187E/pt unknown
- 1999-08-26 AR ARP990104275A patent/AR016505A1/es active IP Right Grant
- 1999-08-26 ZA ZA9905489A patent/ZA995489B/xx unknown
- 1999-08-26 IN IN1154DE1999 patent/IN191812B/en unknown
- 1999-08-26 RU RU99118667/13A patent/RU2203954C2/ru not_active IP Right Cessation
- 1999-08-26 CA CA002280994A patent/CA2280994C/en not_active Expired - Fee Related
- 1999-08-26 IL IL13161399A patent/IL131613A0/xx not_active IP Right Cessation
- 1999-08-27 HU HU9902903A patent/HU226215B1/hu not_active IP Right Cessation
- 1999-08-27 CZ CZ0308099A patent/CZ298476B6/cs not_active IP Right Cessation
- 1999-08-27 JP JP11241588A patent/JP3103539B2/ja not_active Expired - Fee Related
- 1999-08-27 AU AU44825/99A patent/AU749873B2/en not_active Ceased
- 1999-08-27 KR KR1019990035984A patent/KR100338917B1/ko not_active Expired - Fee Related
- 1999-08-27 CN CNB2004100459930A patent/CN1271209C/zh not_active Expired - Fee Related
- 1999-08-27 PL PL335149A patent/PL197322B1/pl not_active IP Right Cessation
- 1999-08-27 TR TR1999/02097A patent/TR199902097A2/xx unknown
- 1999-08-27 CN CNB991183150A patent/CN1177935C/zh not_active Expired - Fee Related
- 1999-08-30 BR BR9903971-0A patent/BR9903971A/pt not_active Application Discontinuation
-
2000
- 2000-03-09 JP JP2000064727A patent/JP2000279189A/ja active Pending
-
2008
- 2008-02-18 CY CY20081100192T patent/CY1107291T1/el unknown
Also Published As
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| Publication | Publication Date | Title |
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| CN1177935C (zh) | 微生物生物转化法 | |
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| EP1290208A1 (en) | Method for optically resolving a racemic alpha-substituted heterocyclic carboxylic acid using enzyme | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1028068 Country of ref document: HK |
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| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20041201 Termination date: 20090928 |