CN117586855B - Incubator for laboratory - Google Patents
Incubator for laboratory Download PDFInfo
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- CN117586855B CN117586855B CN202311647680.1A CN202311647680A CN117586855B CN 117586855 B CN117586855 B CN 117586855B CN 202311647680 A CN202311647680 A CN 202311647680A CN 117586855 B CN117586855 B CN 117586855B
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 45
- 230000005540 biological transmission Effects 0.000 claims abstract description 38
- 239000000523 sample Substances 0.000 claims description 26
- 239000007788 liquid Substances 0.000 claims description 25
- 230000008878 coupling Effects 0.000 claims description 13
- 238000010168 coupling process Methods 0.000 claims description 13
- 238000005859 coupling reaction Methods 0.000 claims description 13
- 230000002093 peripheral effect Effects 0.000 claims description 11
- 238000001125 extrusion Methods 0.000 claims description 8
- 230000006835 compression Effects 0.000 claims description 6
- 238000007906 compression Methods 0.000 claims description 6
- 230000001954 sterilising effect Effects 0.000 claims description 6
- 238000012544 monitoring process Methods 0.000 claims description 5
- 238000004891 communication Methods 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 abstract description 44
- 230000033001 locomotion Effects 0.000 abstract description 17
- 239000012295 chemical reaction liquid Substances 0.000 abstract description 11
- 230000009286 beneficial effect Effects 0.000 abstract description 7
- 230000001360 synchronised effect Effects 0.000 abstract description 3
- 239000007805 chemical reaction reactant Substances 0.000 abstract 2
- 238000012360 testing method Methods 0.000 description 18
- 239000000376 reactant Substances 0.000 description 11
- 230000000694 effects Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000000428 dust Substances 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 241000233866 Fungi Species 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006757 chemical reactions by type Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/10—Rotating vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/16—Vibrating; Shaking; Tilting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
- C12M41/22—Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Molecular Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention relates to the technical field of incubators, in particular to an incubator for a laboratory. The device comprises a box body, wherein an external component is arranged on the surface of the box body, a clamping component, a water bath component and a positive pressure component are respectively arranged in the box body, a vibrating frame is connected to the inner wall of the box body in a sliding manner, a reciprocating vibrating component which drives the vibrating frame to reciprocate in a set stroke is arranged on the surface of the box body, a vibrating shaft is connected to a transmission end of the reciprocating vibrating component in a transmission manner, and a male rotating frame is connected between the inner surfaces of the vibrating frame in a rotating manner. The beneficial effects of the invention are as follows: the invention can make the reaction liquid and reactant in the reaction culture tube generate multiple-effect movement in a set state by the synchronous rotation and reciprocating movement of the vibration shaft, and can make the concentration of the reaction liquid and reactant uniform and effectively disperse and mix during the culture reaction of the reaction culture tube and then fully culture the reaction by the generation of the multiple-effect movement.
Description
Technical Field
The invention relates to the technical field of incubators, in particular to an incubator for a laboratory.
Background
The current incubator is provided with the chamber door of taking the observation window generally, has super cavity glass structure, ensures good observation effect and moisturizing effect, but under the circumstances that the sample put more in the incubator, especially the degree of change of some sample tissue is comparatively tiny, often is difficult to directly observe clearly from the outside of incubator, and opens the chamber door again and introduce miscellaneous fungus easily, causes the destruction of sample.
In order to solve the technical problems in the prior art, patent document CN114752471B discloses an incubator for a biological laboratory, which can drive a magnifier to a proper position to perform auxiliary amplification observation of a biological sample without opening a door, but for cell culture of temperature reaction type, the concentration of reactants and reaction liquid in the reaction process is required to be uniform during the culture, while the incubator in the prior art adopts a static culture structure, so that the problem of uniform concentration and sufficient reaction in the culture process is difficult to solve.
Disclosure of Invention
Aiming at the technical problems in the prior art, the invention provides an incubator for a laboratory to solve the problems that the incubator in the prior art adopts a static culture structure, and the concentration uniformity and the full reaction in the culture process are difficult to solve.
The technical scheme for solving the technical problems is as follows: the utility model provides a laboratory incubator, includes the box, the surface mounting of box has external subassembly, clamping part, water bath subassembly and malleation part are installed respectively to the inside of box, the inner wall sliding connection of box has the vibration frame, the surface mounting of box has the reciprocal vibration that drives the vibration frame and reciprocate in the settlement stroke and moves the part, the transmission end transmission of reciprocal vibration moves the part is connected with the vibration and moves the axle, the rotation is connected with revolution frame between the internal surface of vibration frame, the tip and the revolution frame rotation of vibration move the axle are connected, install a set of bearing module that is circumference array distribution between the internal surface of revolution frame, the inner wall fixed mounting of box has outer ring gear;
The bearing module comprises two symmetrically arranged self-rotating seats which are rotationally connected to the inner wall of the revolution frame, a driven tooth post which is in transmission connection with an outer tooth ring is fixedly arranged at the tail part of the self-rotating seat, eccentric shafts are rotationally connected to the eccentric positions of the self-rotating seats, inner gears are fixedly arranged on the peripheral side surfaces of the eccentric shafts, inner tooth rings which are coaxially arranged with the self-rotating seat and are in transmission connection with the inner gears are fixedly arranged on the surfaces of the revolution frame and adjacent to the inner gears, brackets are fixedly arranged between the opposite surfaces of the eccentric shafts, clamping plates are slidably connected to the inner walls of the brackets, compression springs are arranged between the opposite surfaces of the clamping plates and the brackets, and an extrusion bag is fixedly arranged between the clamping plates and the opposite surfaces of the brackets and communicated with the clamping components.
The beneficial effects of the invention are as follows:
1. when the invention is used, through the arrangement of the motor, the coupling, the reset spring and the semi-missing gear, after the motor outputs the rotating speed, the vibration shaft can rotate at the set speed when the reciprocating movement at the set speed occurs, the reaction liquid and the reactant in the reaction culture test tube can generate multi-effect movement in the set state through the synchronous rotation and the reciprocating movement of the vibration shaft, and the concentration of the reaction liquid and the reactant can be uniformly dispersed and mixed during the culture reaction of the reaction culture test tube through the generation of the multi-effect movement, so that the full culture reaction can be performed.
2. When the invention is used, the reaction liquid and the reactant in the reaction culture test tube are circularly turned over in a multi-effect state by the eccentric arrangement of the eccentric shaft and the rotation of the eccentric shaft during the working, so that the reaction efficiency and the reaction effect of the reaction liquid and the reactant are improved.
3. According to the invention, when the reaction culture test tube is used for culture operation, enough water bath liquid is filled in the water bath cavity, the filling height of the water bath liquid is up to the layout height of the liquid level sensor, and after the water bath liquid is filled in the water bath cavity, the heater is used for heating the liquid in the water bath cavity at constant temperature, so that the reaction culture test tube can perform constant-temperature water bath culture reaction during culture, and when the reaction culture test tube is used, the pressure in the box body is maintained to be 1.1-1.3 times of normal pressure through the arrangement of the pressurizing tube, the pressurizing pump and the second air pressure probe, and the pressure in the box body is maintained through the positive pressure environment in the box body, so that the probability that external dust and dirt and other bacteria enter the box body is effectively reduced.
On the basis of the technical scheme, the invention can be improved as follows.
Further, the outside subassembly is including installing in singlechip and chamber door at box top, installing in two operating tubes of box terminal surface and being fixed in the humiture probe on box surface, two the tail end of operating tube all communicates there is the rubber gloves, the fixed surface of chamber door is provided with the observation window, humiture probe's monitoring end extends to the inner chamber of box, humiture probe's port is connected with the singlechip electricity, the interior upper portion of box embeds there is the ultraviolet sterilizing lamp.
The technical scheme has the advantages that when the box is used, the manual sterile operation is conveniently carried out on the culture test tube installed in the box body under the condition that the box door is not opened through the arrangement of the operation tube and the rubber glove, the visual observation is conveniently carried out on the reaction culture test tube through the arrangement of the observation window, and the real-time monitoring can be carried out on the temperature and humidity data inside the box body through the arrangement of the temperature and humidity probe;
Through the arrangement of the ultraviolet sterilizing lamp, the bacteria content in the box body during the culture operation is effectively reduced.
Further, the clamping component comprises an air pump fixed on the side face of the box body and an air guide ring pipe fixed on the surface of the revolution rack and coaxially arranged with the revolution rack, an air inlet ring is rotationally connected to the inner wall of the air guide ring pipe, a port of the air pump is fixedly communicated with the air inlet ring through a hose, a group of air holes distributed in a circumferential array are formed in the air guide ring pipe, a first air pressure probe connected with the single-chip microcomputer is fixedly arranged at the communicating position of the air pump and the air inlet ring, and an air inlet runner rotationally communicated with the air inlet ring is fixedly arranged at the axis position of the extrusion bag.
The beneficial effect of adopting above-mentioned further scheme is, during the use, through the setting of first air pressure probe to the real-time supervision extrusion bag is to the extrusion strength of reaction culture test tube and the spacing intensity of reaction culture test tube.
Further, the water bath subassembly is including offering the water bath chamber in the box bottom respectively, the inside fixed mounting in water bath chamber has the heater, the inside fixed mounting of box have with water bath chamber complex level sensor, level sensor's data end is connected with the monolithic is electromechanical, level sensor's layout height is the half height of box, drain valve and the feed liquor valve with water bath chamber intercommunication are installed respectively to the both sides face of box, a set of regular distribution and with water bath chamber complex liquid permeation hole have been offered to the inside of frame that shakes.
Adopt the beneficial effect of above-mentioned further scheme, when the reaction cultivates the test tube and cultivates the operation, the inside of water bath chamber fills into sufficient water bath liquid, and the filling height of water bath liquid is up to level sensor's laying height, and after the water bath liquid was filled into to the inside of water bath chamber, the heater carries out constant temperature heating to the liquid of water bath intracavity portion to make the reaction cultivate the test tube and cultivate the time can carry out the constant temperature water bath and cultivate the reaction.
Further, the positive pressure component respectively comprises a pressurizing pump fixed on the side face of the box body and a pressurizing pipe fixed between the inner surfaces of the male rotating frame, a filter is installed at a port of the pressurizing pump, the pressurizing port of the pressurizing pump is communicated with the pressurizing pipe in a rotating mode through a soft guide pipe, a plurality of groups of partial pressure holes distributed in a circumferential array are formed in the pressurizing pipe, the axis of the pressurizing pipe and the rotating axis of the male rotating frame are in the same straight line, and a second air pressure probe connected with the single-chip microcomputer is fixedly arranged at a communicating position of the pressurizing pump and the pressurizing pipe.
The beneficial effect of adopting the further scheme is that when in use, the pressure inside the box body is maintained to be 1.1-1.3 times of normal pressure through the arrangement of the pressurizing pipe, the pressurizing pump and the second air pressure probe;
The positive pressure environment in the box body is maintained, so that the probability that external dust and dirt and bacteria enter the box body is effectively reduced, and the pressurizing pump is continuously opened when the box door is opened.
Further, the reciprocating vibration part comprises a motor fixed on the inner wall of the box body, a mandrel rotationally connected to the inner wall of the box body and a shaft coupling, a transmission shaft is fixedly arranged at the output shaft end of the motor, a transmission bevel gear is fixedly arranged on the peripheral side surface of the transmission shaft, a driven bevel gear meshed with the transmission bevel gear is fixedly arranged at the tail part of the mandrel, the peripheral side surface of the mandrel is in transmission connection with the vibration shaft and in sliding fit with the vibration shaft, the peripheral side surface of the mandrel is in transmission connection with the shaft coupling through a chain, a semi-missing gear is fixedly arranged on the peripheral side surface of the shaft coupling, a guide toothed plate in transmission connection with the semi-missing gear is fixedly arranged on the side surface of the vibration frame, and a group of reset springs are arranged between the vibration frame and the opposite surfaces of the box body.
Further, the inside of the vibration shaft is fixedly provided with a shaft groove with an opening at the tail end and in sliding connection with the mandrel, the cross sections of the shaft groove and the mandrel are regular polygons, and the movable direction of the guide toothed plate is parallel to the axis of the vibration shaft.
Further, the circumference side of the semi-missing gear is symmetrically provided with a tooth part and a toothless part, the whole radian of the tooth part is 180 degrees, and the surface of the tooth part is uniformly provided with transmission teeth.
The adoption of the further scheme has the beneficial effects that when in use, through the arrangement of the motor, the coupling, the return spring and the semi-missing gear, after the motor outputs the rotating speed, the vibration shaft can rotate at the set speed when the reciprocating movement at the set speed occurs;
Through shaking the synchronous emergence of axle rotation and reciprocating motion to make reaction solution and reactant in the reaction culture tube can take place the multiple effect motion of settlement state, through the emergence of multiple effect motion, thereby make reaction culture tube when cultivateing the reaction concentration homogeneous of reaction solution and reactant and can effectively disperse the mixing and then carry out abundant culture reaction.
Further, the tooth length of driven tooth post is 4-8 times of external tooth ring gear tooth length, the cross section of bracket is the U-shaped, the top surface of splint installs the pan feeding guide piece, the fixed guide cambered surface that is provided with in junction of pan feeding guide piece and splint.
The beneficial effect of adopting above-mentioned further scheme is, during the use, through the setting of driven tooth post tooth length and external tooth ring gear tooth length to make to shake and move the frame at the in-process of displacement, external tooth ring can last effective transmission to driven tooth post.
Drawings
FIG. 1 is a schematic view showing the overall structure of an incubator for laboratory of the present invention;
FIG. 2 is a schematic cross-sectional view of the partial pressure port and the water bath chamber of the present invention;
FIG. 3 is a schematic view of a partial enlarged structure at A in FIG. 2 according to the present invention;
FIG. 4 is a schematic view of a partially enlarged structure of the present invention at B in FIG. 2;
FIG. 5 is a schematic view showing a partially enlarged structure of the reaction culture tube of FIG. 2 according to the present invention;
FIG. 6 is a schematic view of the structure of the support module and the vibration frame of the present invention;
FIG. 7 is a schematic view of a partially enlarged structure of the present invention at D in FIG. 6;
Fig. 8 is a schematic view of a partial enlarged structure at E in fig. 6 according to the present invention.
In the drawings, the list of components represented by the various numbers is as follows:
1. A case; 2. vibrating the frame; 3. vibrating the shaft; 4. a male rotating frame; 5. a bearing module; 6. an outer ring gear; 7. a single chip microcomputer; 8. a door; 9. an operating tube; 10. a temperature and humidity probe; 11. an ultraviolet sterilizing lamp; 12. an air guide ring pipe; 13. an air inlet ring; 14. an air pump; 15. ventilation holes; 16. a water bath cavity; 17. a heater; 18. a liquid level sensor; 19. a liquid-permeable hole; 20. a pressurizing pump; 21. a partial pressure hole; 22. a motor; 23. a mandrel; 24. coupling shaft; 25. a transmission shaft; 26. a half-gear; 27. a guide toothed plate; 28. a return spring; 29. feeding guide sheets; 30. a pressurizing tube; 51. a spin stand; 52. a driven tooth post; 53. an eccentric shaft; 54. an internal gear; 55. an inner gear ring; 56. a bracket; 57. a clamping plate; 58. a compression spring; 59. the bladder is squeezed.
Description of the embodiments
The principles and features of the present invention are described below with reference to the drawings, the examples are illustrated for the purpose of illustrating the invention and are not to be construed as limiting the scope of the invention.
The present invention provides the following preferred embodiments
As shown in fig. 1 to 8, an incubator for laboratory comprises a case 1, a surface of the case 1 being mounted with external components;
The external component comprises a singlechip 7 and a box door 8 which are arranged at the top of the box body 1, two operation pipes 9 which are arranged on the end face of the box body 1 and a temperature and humidity probe 10 which is fixed on the surface of the box body 1, wherein the tail ends of the two operation pipes 9 are respectively communicated with rubber gloves, an observation window is fixedly arranged on the surface of the box door 8, the monitoring end of the temperature and humidity probe 10 extends to the inner cavity of the box body 1, the port of the temperature and humidity probe 10 is electrically connected with the singlechip 7, and an ultraviolet sterilizing lamp 11 is arranged in the inner upper part of the box body 1.
When the incubator is used, the manual sterile operation is conveniently carried out on the culture test tube installed in the case body 1 under the non-opening state of the case door 8 through the arrangement of the operation tube 9 and the rubber glove, the visual observation is conveniently carried out on the reaction culture test tube through the arrangement of the observation window, and the real-time monitoring can be carried out on the temperature and humidity data in the case body 1 through the arrangement of the temperature and humidity probe 10;
By the arrangement of the ultraviolet sterilizing lamp 11, the bacteria content in the case 1 during the culturing operation is effectively reduced.
The clamping part, the water bath component and the positive pressure part are respectively arranged in the box body 1;
The water bath assembly comprises a water bath cavity 16 which is arranged at the bottom of the box body 1, a heater 17 is fixedly arranged in the water bath cavity 16, a liquid level sensor 18 which is matched with the water bath cavity 16 is fixedly arranged in the box body 1, the data end of the liquid level sensor 18 is electrically connected with the singlechip 7, the arrangement height of the liquid level sensor 18 is one half of the height of the box body 1, and a drain valve and a liquid inlet valve which are communicated with the water bath cavity 16 are respectively arranged on two side surfaces of the box body 1;
When the reaction culture test tube is subjected to culture operation, enough water bath liquid is filled in the water bath cavity 16, the filling height of the water bath liquid is up to the layout height of the liquid level sensor 18, and after the water bath liquid is filled in the water bath cavity 16, the heater 17 is used for heating the liquid in the water bath cavity 16 at constant temperature, so that the reaction culture test tube can perform constant-temperature water bath culture reaction when being cultured.
The inner wall of the box body 1 is connected with a vibrating frame 2 in a sliding manner, a group of liquid-permeable holes 19 which are regularly distributed and matched with the water bath cavity 16 are formed in the vibrating frame 2, a reciprocating vibrating part which drives the vibrating frame 2 to reciprocate in a set stroke is arranged on the surface of the box body 1, and a vibrating shaft 3 is connected with a transmission end of the reciprocating vibrating part in a transmission manner;
The reciprocating vibration part comprises a motor 22 fixed on the inner wall of the box body 1, a mandrel 23 and a shaft coupling 24 which are rotatably connected with the inner wall of the box body 1, wherein the peripheral side surface of the mandrel 23 is in transmission connection with the shaft coupling 24 through a chain, a transmission shaft 25 is fixedly arranged at the output shaft end of the motor 22, a transmission bevel gear is fixedly arranged at the peripheral side surface of the transmission shaft 25, and a driven bevel gear meshed with the transmission bevel gear is fixedly arranged at the tail part of the mandrel 23;
The peripheral side surface of the mandrel 23 is in transmission connection with the vibrating shaft 3 and in sliding fit;
The inside of the vibration shaft 3 is fixedly provided with a shaft groove with an opening at the tail end and in sliding connection with the mandrel 23, and the cross sections of the shaft groove and the mandrel 23 are regular polygons;
The spindle groove and the regular polygon cross section of the spindle 23 are arranged, so that the spindle 23 can continuously and effectively drive the vibration spindle 3 in the reciprocating movement process of the vibration spindle 3;
the circumference side surface of the coupling 24 is fixedly provided with a half-cut gear 26, and the side surface of the vibration frame 2 is fixedly provided with a guide toothed plate 27 which is in transmission connection with the half-cut gear 26;
the peripheral side surface of the semi-missing gear 26 is symmetrically provided with a tooth part and a toothless part, the whole radian of the tooth part is 180 degrees, and the surface of the tooth part is uniformly provided with transmission teeth;
the movable direction of the guide toothed plate 27 is parallel to the axis of the oscillating shaft 3
A set of return springs 28 are mounted between the opposed surfaces of the vibrating frame 2 and the housing 1.
When in use, the motor 22, the coupling 24, the return spring 28 and the half-cut gear 26 are arranged, so that the vibration shaft 3 can rotate at a set speed when reciprocating at the set speed after the motor 22 outputs the rotating speed;
The vibration shaft 3 rotates and reciprocates synchronously, so that the reaction liquid and the reactant in the reaction culture tube can generate multiple-effect movement in a set state, and the concentration of the reaction liquid and the concentration of the reactant in the reaction culture tube can be uniformly dispersed and mixed during the culture reaction, so that the full culture reaction can be carried out.
A revolution frame 4 is rotationally connected between the inner surfaces of the vibration frame 2, the end part of the vibration shaft 3 is rotationally connected with the revolution frame 4, a group of bearing modules 5 distributed in a circumferential array are arranged between the inner surfaces of the revolution frame 4, and an outer gear ring 6 is fixedly arranged on the inner wall of the box body 1;
The bearing module 5 comprises two spin seats 51 which are symmetrically arranged and are rotationally connected to the inner wall of the revolution frame 4, and a driven tooth column 52 which is in transmission connection with the outer gear 6 is fixedly arranged at the tail part of one spin seat 51;
the tooth length of the driven tooth post 52 is 8 times of the tooth length of the outer tooth ring 6;
when the vibration frame 2 is used, the external gear ring 6 can continuously and effectively drive the driven gear column 52 in the displacement process through the arrangement of the tooth length of the driven gear column 52 and the tooth length of the external gear ring 6;
eccentric positions of the two spin seats 51 are respectively and rotatably connected with an eccentric shaft 53, an inner gear 54 is fixedly arranged on the peripheral side surface of one eccentric shaft 53, and an inner gear ring 55 which is coaxially arranged with the spin seats 51 and in transmission connection with the inner gear 54 is fixedly arranged on the surface of the revolution frame 4 and adjacent to the inner gear 54;
When the revolution frame 4 performs revolution motion, the driven tooth post 52 is connected with the outer tooth ring 6, so that the spin seat 51 can perform spin motion when the revolution frame 4 performs revolution motion, and when the spin seat 51 performs spin motion, the eccentric shaft 53 can rotate again when the spin seat 51 performs spin through the connection between the inner gear 54 and the inner tooth ring 55;
A bracket 56 is fixedly arranged between the opposite surfaces of the two eccentric shafts 53, and the cross section of the bracket 56 is U-shaped;
Through the eccentric arrangement of the eccentric shaft 53 and the rotation of the eccentric shaft 53 during the working, the reaction liquid and the reactant in the reaction culture tube are circularly turned over in a multi-effect state, so that the reaction efficiency and the reaction effect of the reaction liquid and the reactant are improved;
The inner walls of the two brackets 56 are both in sliding connection with clamping plates 57, the top surface of the clamping plates 57 is provided with a feeding guide sheet 29, a guide cambered surface is fixedly arranged at the joint of the feeding guide sheet 29 and the clamping plates 57, compression springs 58 are mounted between the two clamping plates 57 and the opposite surfaces of the brackets 56, a compression bag 59 is fixedly mounted between one clamping plate 57 and the opposite surface of the brackets 56, and the surface of the compression bag 59 is communicated with the clamping part.
The clamping component comprises an air pump 14 fixed on the side face of the box body 1 and an air guide ring pipe 12 fixed on the surface of the revolution rack 4 and coaxially arranged with the revolution rack 4, an air inlet ring 13 is rotationally connected to the inner wall of the air guide ring pipe 12, ports of the air pump 14 are fixedly communicated with the air inlet ring 13 through hoses, a group of air holes 15 distributed in a circumferential array are formed in the air guide ring pipe 12, a first air pressure probe electrically connected with the single chip microcomputer 7 is fixedly arranged at the communication position of the air pump 14 and the air inlet ring 13, and an air inlet runner rotationally communicated with the air inlet ring 13 is fixedly arranged at the axial position of the extrusion bag 59.
When in use, the extrusion strength of the extrusion bag 59 to the reaction culture test tube and the limited strength of the reaction culture test tube are monitored in real time through the arrangement of the first air pressure probe.
The positive pressure component respectively comprises a pressurizing pump 20 fixed on the side surface of the box body 1 and a pressurizing pipe 30 fixed between the inner surfaces of the revolution rack 4, a filter is arranged at a port of the pressurizing pump 20, the pressurizing port of the pressurizing pump 20 is rotationally communicated with the pressurizing pipe 30 through a flexible conduit, a plurality of groups of pressure dividing holes 21 distributed in a circumferential array are formed in the pressurizing pipe 30, the axis of the pressurizing pipe 30 and the rotation axis of the revolution rack 4 are in the same straight line, and a second air pressure probe electrically connected with the single chip microcomputer 7 is fixedly arranged at a communicating position of the pressurizing pump 20 and the pressurizing pipe 30.
When in use, the pressure inside the box body 1 is maintained to be 1.2 times of normal pressure through the arrangement of the pressurizing pipe 30, the pressurizing pump 20 and the second air pressure probe;
The positive pressure environment in the box body 1 is maintained, so that the probability that external dust and dirt enter the box body 1 is effectively reduced, and the pressurizing pump 20 is continuously started when the box door 8 is opened.
In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present invention.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present invention, the meaning of "plurality" means at least two, for example, two, three, etc., unless specifically defined otherwise.
The foregoing description of the preferred embodiments of the invention is not intended to limit the invention to the precise form disclosed, and any such modifications, equivalents, and alternatives falling within the spirit and scope of the invention are intended to be included within the scope of the invention.
Claims (4)
1. The incubator for the laboratory comprises a box body (1), and is characterized in that an external component is arranged on the surface of the box body (1), a clamping component, a water bath component and a positive pressure component are respectively arranged in the box body (1), a vibrating frame (2) is connected to the inner wall of the box body (1) in a sliding manner, and a reciprocating vibrating component for driving the vibrating frame (2) to reciprocate in a set stroke is arranged on the surface of the box body (1);
The transmission end of the reciprocating vibration part is in transmission connection with a vibration shaft (3), a male rotating frame (4) is rotationally connected between the inner surfaces of the vibration frames (2), the end part of the vibration shaft (3) is rotationally connected with the male rotating frame (4), a group of bearing modules (5) distributed in a circumferential array are arranged between the inner surfaces of the male rotating frame (4), and an outer gear ring (6) is fixedly arranged on the inner wall of the box body (1);
The bearing module (5) comprises two symmetrically arranged spin seats (51) which are rotationally connected to the inner wall of the male rotating frame (4), a driven tooth column (52) which is in transmission connection with the outer tooth ring (6) is fixedly arranged at the tail part of one spin seat (51), eccentric shafts (53) are rotationally connected to the eccentric positions of the two spin seats (51), and an inner gear (54) is fixedly arranged on the peripheral side surface of one eccentric shaft (53);
An inner gear ring (55) which is coaxially arranged with the spin base (51) and is in transmission connection with the inner gear (54) is fixedly arranged on the surface of the revolution frame (4) and adjacent to the inner gear (54), a bracket (56) is fixedly arranged between the opposite surfaces of the two eccentric shafts (53), clamping plates (57) are slidably connected to the inner walls of the two brackets (56), compression springs (58) are arranged between the two clamping plates (57) and the opposite surfaces of the bracket (56), a pressing bag (59) is fixedly arranged between the clamping plates (57) and the opposite surfaces of the bracket (56), and the surfaces of the pressing bag (59) are communicated with the clamping parts; The external assembly comprises a singlechip (7) and a box door (8) which are arranged at the top of the box body (1), two operation pipes (9) which are arranged on the end face of the box body (1) and a temperature and humidity probe (10) which is fixed on the surface of the box body (1), wherein the tail ends of the two operation pipes (9) are communicated with rubber gloves, an observation window is fixedly arranged on the surface of the box door (8), the monitoring end of the temperature and humidity probe (10) extends to the inner cavity of the box body (1), the port of the temperature and humidity probe (10) is electrically connected with the singlechip (7), and an ultraviolet sterilizing lamp (11) is arranged in the inner upper part of the box body (1); The clamping component comprises an air pump (14) fixed on the side surface of the box body (1) and an air guide ring pipe (12) fixed on the surface of the revolution rack (4) and coaxially arranged with the revolution rack (4), an air inlet ring (13) is rotationally connected to the inner wall of the air guide ring pipe (12), a port of the air pump (14) is fixedly communicated with the air inlet ring (13) through a hose, a group of air holes (15) distributed in a circumferential array are formed in the air guide ring pipe (12), a first air pressure probe electrically connected with the singlechip (7) is fixedly arranged at the communication position of the air pump (14) and the air inlet ring (13), and an air inlet flow passage rotationally communicated with the air inlet ring (13) is fixedly arranged at the axis position of the extrusion bag (59); The water bath assembly comprises a water bath cavity (16) formed in the bottom of the box body (1), a heater (17) is fixedly arranged in the water bath cavity (16), a liquid level sensor (18) matched with the water bath cavity (16) is fixedly arranged in the box body (1), the data end of the liquid level sensor (18) is electrically connected with the singlechip (7), the distribution height of the liquid level sensor (18) is one half of the height of the box body (1), a drain valve and a liquid inlet valve which are communicated with the water bath cavity (16) are respectively arranged on two side surfaces of the box body (1), and a group of liquid permeable holes (19) which are regularly distributed and matched with the water bath cavity (16) are formed in the vibration frame (2); the positive pressure component comprises a pressurizing pump (20) fixed on the side surface of the box body (1) and a pressurizing pipe (30) fixed between the inner surfaces of the male rotating frame (4), a filter is arranged at a port of the pressurizing pump (20), the pressurizing port of the pressurizing pump (20) is rotationally communicated with the pressurizing pipe (30) through a soft conduit, a plurality of groups of pressure dividing holes (21) distributed in a circumferential array are formed in the pressurizing pipe (30), the axis of the pressurizing pipe (30) and the rotating axis of the male rotating frame (4) are in the same straight line, and a second air pressure probe electrically connected with the single chip microcomputer (7) is fixedly arranged at the communicating position of the pressurizing pump (20) and the pressurizing pipe (30);
The reciprocating vibration part comprises a motor (22) fixed on the inner wall of the box body (1), a mandrel (23) connected with the inner wall of the box body (1) in a rotating way and a shaft coupling (24);
The utility model discloses a motor, including motor (22), shaft (25) are fixed firmly to the output shaft end, the week side fixed mounting of shaft (25) has transmission bevel gear, the afterbody fixed mounting of dabber (23) has driven bevel gear with transmission bevel gear meshing, the week side of dabber (23) is connected and sliding fit with the transmission of shake and move axle (3), the week side of dabber (23) is connected with shaft coupling (24) transmission through the chain, the week side fixed mounting of shaft coupling (24) has half-missing gear (26), the side fixed mounting of shake and move frame (2) has guide pinion rack (27) of being connected with half-missing gear (26) transmission, shake and move and install a set of reset spring (28) between the relative surface of frame (2) and box (1).
2. The incubator according to claim 1, wherein the inside of the vibration shaft (3) is fixedly provided with a shaft groove with an opening at the tail end and in sliding connection with the mandrel (23), the cross sections of the shaft groove and the mandrel (23) are both regular polygons, and the movable direction of the guide toothed plate (27) is parallel to the axis of the vibration shaft (3).
3. The incubator according to claim 2, wherein the circumferential side of the semi-missing gear (26) is symmetrically provided with a tooth part and a toothless part, the whole radian of the tooth part is 180 degrees, and transmission teeth are uniformly distributed on the surface of the tooth part.
4. The incubator for laboratory according to claim 1, wherein the tooth length of the driven tooth column (52) is 4-8 times of the tooth length of the outer gear (6), the cross section of the bracket (56) is U-shaped, the top surface of the clamping plate (57) is provided with a feeding guide sheet (29), and a guide cambered surface is fixedly arranged at the joint of the feeding guide sheet (29) and the clamping plate (57).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311647680.1A CN117586855B (en) | 2023-12-04 | 2023-12-04 | Incubator for laboratory |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311647680.1A CN117586855B (en) | 2023-12-04 | 2023-12-04 | Incubator for laboratory |
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| CN117586855A CN117586855A (en) | 2024-02-23 |
| CN117586855B true CN117586855B (en) | 2024-07-05 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804402A (en) * | 2010-04-19 | 2010-08-18 | 上海智城分析仪器制造有限公司 | Amplitude stepless adjustable mechanism for culture oscillator |
| CN107815410A (en) * | 2017-12-01 | 2018-03-20 | 周迪 | A kind of observation incubator of Experiment on Microbiology |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108048316A (en) * | 2018-01-19 | 2018-05-18 | 绿宁农业科技（苏州）有限公司 | A kind of automatic biological culture machine |
| CN109852546B (en) * | 2019-04-03 | 2020-01-31 | 崔建英 | Pollution-free culture system and method for cells |
| CN110732271B (en) * | 2019-11-26 | 2020-07-21 | 王超 | Platelet vibration storage box |
| CN111748473B (en) * | 2020-07-23 | 2021-03-30 | 湖南南华爱世普林生物技术有限公司 | Medical cell culture equipment and cell culture method |
| CN214991653U (en) * | 2021-11-05 | 2021-12-03 | 山东畜牧兽医职业学院 | External embryo culture device is used to ox |
| CN115449462A (en) * | 2022-08-18 | 2022-12-09 | 安徽珠峰生物科技有限公司 | Microbial flora storage device and storage method thereof |
| CN115975774A (en) * | 2022-12-30 | 2023-04-18 | 田茂瑾 | Anti-pollution formula bacteria culture device of microbiological assay |
| CN117071387A (en) * | 2023-09-04 | 2023-11-17 | 姜艺洋 | Highway maintenance cementation of fissures equipment |
-
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804402A (en) * | 2010-04-19 | 2010-08-18 | 上海智城分析仪器制造有限公司 | Amplitude stepless adjustable mechanism for culture oscillator |
| CN107815410A (en) * | 2017-12-01 | 2018-03-20 | 周迪 | A kind of observation incubator of Experiment on Microbiology |
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