CN117224992A - A kind of nicotinamide mononucleotide cooling crystallization device - Google Patents
A kind of nicotinamide mononucleotide cooling crystallization device Download PDFInfo
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- CN117224992A CN117224992A CN202311278350.XA CN202311278350A CN117224992A CN 117224992 A CN117224992 A CN 117224992A CN 202311278350 A CN202311278350 A CN 202311278350A CN 117224992 A CN117224992 A CN 117224992A
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Abstract
一种烟酰胺单核苷酸降温结晶装置，包括加热釜、结晶釜、过滤结构、缓流结构和刮料结构，本发明涉及烟酰胺单核苷酸生产技术领域，所述加热釜下端中部设置有控制阀，控制阀下侧设置有过滤结构，加热釜右侧设置有结晶釜，结晶釜内部上侧设置有缓流结构，结晶釜左下侧设置有刮料结构；装置通过过滤结构来对待结晶溶液内部的杂质进行筛分，进而提高后续烟酰胺单核苷酸结晶的质量和纯度；通过溶液在倾斜板上的流动中来有效地降低溶液的流速，使溶液可以在结晶釜内充分反应，提高结晶釜内溶液的降温效率，使得溶液可以更加充分地析出晶体，通过倾斜板的上下移动中来带动少量黏附在倾斜板上的溶液和析出的晶体向下移动。
A cooling crystallization device for nicotinamide mononucleotide, including a heating kettle, a crystallization kettle, a filter structure, a slow flow structure and a scraper structure. The invention relates to the technical field of nicotinamide mononucleotide production. The heating kettle is provided in the middle of the lower end of the kettle. There is a control valve, a filter structure is provided on the lower side of the control valve, a crystallization kettle is installed on the right side of the heating kettle, a slow flow structure is provided on the upper side of the crystallization kettle, and a scraping structure is provided on the lower left side of the crystallization kettle; the device treats crystallization through the filtration structure The impurities inside the solution are screened, thereby improving the quality and purity of subsequent nicotinamide mononucleotide crystallization; the flow rate of the solution is effectively reduced by the flow of the solution on the inclined plate, so that the solution can fully react in the crystallization kettle, Improve the cooling efficiency of the solution in the crystallization kettle, so that the solution can more fully precipitate crystals, and the up and down movement of the inclined plate drives a small amount of solution adhering to the inclined plate and the precipitated crystals to move downward.
Description
Technical Field
The application relates to the technical field of nicotinamide mononucleotide production, in particular to a nicotinamide mononucleotide cooling crystallization device.
Background
Nicotinamide mononucleotide plays an important role in human cell energy production, and it is involved in the synthesis of intracellular NAD (nicotinamide adenine dinucleotide, an important coenzyme for cell energy conversion). Nicotinamide mononucleotide is present in the human body as such, but decreases with age. Early experiments prove that nicotinamide mononucleotide NMN can increase NAD in various organs in an experimental mouse, so that the aging of nerves, blood vessels and the like is inhibited, and the diabetes symptom can be improved.
In the existing nicotinamide mononucleotide crystallization process, a solution enters a crystallization kettle for cooling crystallization, the solution after the crystallization is filtered out from a filter plate and directly flows out, the solution flows down from a high position to a low position in the crystallization kettle, the descending speed is high, and a small amount of crystals are easy to separate out insufficiently after the filter plate filters the solution, so that the nicotinamide mononucleotide crystal is produced. In order to solve the problems, the application provides a nicotinamide mononucleotide cooling crystallization device.
Disclosure of Invention
The application provides a nicotinamide mononucleotide cooling crystallization device, which aims to solve the technical problems in the background technology.
In order to solve the problems, the application provides a nicotinamide mononucleotide cooling crystallization device which comprises a heating kettle, a crystallization kettle, a filtering structure, a slow flow structure and a scraping structure.
Preferably, the filter structure comprises a filter chamber, a first fixed plate, a first motor, discs, movable sleeves, movable plates, first limiting sleeves, C-shaped frames and first filter plates, wherein the lower end of a control valve is connected with a discharging pipe, the lower end of the discharging pipe is provided with the filter chamber, the front end of the filter chamber is provided with a box door, the left end and the right end of the filter chamber are respectively provided with the first fixed plates, the upper end of each first fixed plate is provided with the first motor, the output ends of the two first motors penetrate through the discs fixedly connected with the inside of the filter chamber, the two discs are close to one end and are respectively provided with a protruding column, the movable sleeves are arranged outside the protruding columns, the left end and the right end of the inside of the filter chamber are respectively provided with the first limiting sleeves, the inside of each first limiting sleeve is connected with the movable plates in a sliding manner, the lower end of each movable plate is connected with the movable sleeve, the upper end of each movable plate is provided with the C-shaped frames, the two C-shaped frames are symmetrical, and the first filter plates are arranged inside each C-shaped frame;
preferably, the slow flow structure comprises a second limiting sleeve, a sliding plate, an inclined plate, a rotating shaft and an eccentric wheel, wherein two second limiting sleeves and the rotating shaft are arranged at the left end and the right end of the inside of the crystallization kettle, the rotating shaft is positioned at the lower side of the second limiting sleeve, the horizontal positions of the two groups of second limiting sleeves on the left side are higher than those of the two groups of second limiting sleeves on the right side, the sliding plate is connected inside the second limiting sleeve in a sliding manner, the inclined plate is arranged at the upper end of the sliding plate, and the eccentric wheel is arranged on the rotating shaft;
preferably, the scraping structure comprises a threaded rod, an auxiliary rod, a threaded sleeve, a connecting rod, a first gear, a third fixing plate, a third motor and a second gear, wherein the threaded rod and the auxiliary rod are arranged at the lower side of the left end of the crystallization kettle, the auxiliary rod is positioned at the upper side of the threaded rod, the threaded sleeve is connected to the threaded rod in a threaded manner, the connecting rod is arranged at the upper side of the right end of the threaded sleeve, the first gear is arranged on the right side of the outer part of the threaded rod, the third fixing plate is arranged at the left end of the crystallization kettle and positioned at the lower side of the first gear, the third motor is arranged at the upper end of the third fixing plate, the second gear is arranged at the output end of the third motor, and the first gear is in meshed connection with the second gear;
preferably, a feed inlet is formed in the upper left end of the heating kettle, a mounting box is arranged in the middle of the upper end of the heating kettle, a stirring motor is arranged in the mounting box, a stirring rod is arranged at the top end inside the heating kettle, the upper end of the stirring rod penetrates through the heating kettle to be connected with the output end of the stirring motor, and a plurality of stirring blades are arranged on the stirring rod;
preferably, a connecting pipe is arranged at the lower side of the right end of the filtering chamber, a mounting plate is arranged at the upper side of the left end of the crystallization kettle, a pump body is arranged at the upper end of the mounting plate, the inlet end of the pump body is communicated with the connecting pipe, the outlet end of the connecting pipe is communicated with the crystallization kettle, and the outlet end of the connecting pipe penetrates into the crystallization kettle;
preferably, the left end and the right end of the crystallization kettle are both provided with second fixing plates, the horizontal position of the left second fixing plate is higher than that of the right second fixing plate, the upper end of the second fixing plate is provided with a second motor, a plurality of rotating shafts penetrate through the crystallization kettle to be provided with synchronous wheels, a belt is arranged between the two synchronous wheels on the same side, and the two synchronous wheels on the lower side are connected with the output end of the second motor;
preferably, a chute matched with the connecting rod is formed in the lower side of the left end of the crystallization kettle, a scraping plate is arranged at the right end of the connecting rod penetrating through the chute, a second filter plate is arranged at the lower side of the inside of the crystallization kettle, and a liquid discharge pipe with a valve is arranged in the middle of the lower end of the crystallization kettle;
preferably, a discharge groove is formed in the lower side of the right end of the crystallization kettle, a feed groove is formed in the upper side of the left end of the collection box, and the discharge groove is matched with the feed groove;
preferably, the first motor, the stirring motor, the second motor and the third motor are all electrically connected with an external power supply and an external singlechip, and the model of the singlechip is STM32;
the technical scheme of the application has the following beneficial technical effects:
the device accelerates the dissolution speed of materials through the rotation of a plurality of stirring blades, thereby improving the production efficiency of the device, screening impurities in a solution to be crystallized through the arrangement of a filtering structure, further improving the quality and purity of subsequent nicotinamide mononucleotide crystallization, driving the disc to rotate through the first motor while filtering the solution, driving the movable plate to move up and down in the first limiting sleeve by means of the mutual matching of the protruding column on the disc and the movable sleeve, and further driving the C-shaped frame and the first filter plate to reciprocate up and down, thereby accelerating the filtering speed of the solution;
the device reduces the flow rate of the solution through the setting of the slow flow structure, the solution enters the crystallization kettle and can sequentially drop on a plurality of inclined plates, the flow rate of the solution is effectively reduced through the flowing of the solution on the inclined plates, the solution can fully react in the crystallization kettle, the cooling efficiency of the solution in the crystallization kettle is improved, the solution can be more fully separated out of crystals, adjacent synchronous wheels are driven to rotate through a second motor, the rotating shaft is driven to rotate by means of the mutual matching of the synchronous wheels and a belt, a plurality of eccentric wheels are driven to rotate, the sliding plate is pushed upwards to slide in a second limit sleeve in the rotating process of the eccentric wheels, the inclined plates are driven to reciprocate up and down, a small amount of solution adhered to the inclined plates and the separated out crystals are driven to move downwards, and waste is reduced;
the device filters crystals and solution through the second filter plate to intercept the crystals that will separate out on the second filter plate, and the solution accessible that separates out has the fluid-discharge tube of valve to be discharged, after crystallization finishes, drive the second gear through the third motor and rotate, drive the threaded rod and rotate with the help of the meshing of second gear and first gear, and then drive thread bush and connecting rod to move to the right side, can drive the scraper blade to move to the right side at the in-process that the connecting rod moved to the right side in the spout, the crystals on the second filter plate push to the collection box inside under the drive of scraping the flitch, accomplish the collection to the crystals.
Drawings
Fig. 1 is a schematic structural diagram of a nicotinamide mononucleotide cooling crystallization device provided by the application.
Fig. 2 is a front view of a nicotinamide mononucleotide cooling crystallization device provided by the application.
Fig. 3 is an enlarged view of a in a nicotinamide mononucleotide cooling crystallization device according to the application.
Fig. 4 is an enlarged view of B in a nicotinamide mononucleotide cooling crystallization device according to the present application.
Fig. 5 is an enlarged view of B in a nicotinamide mononucleotide cooling crystallization device according to the present application.
Reference numerals: 1. heating the kettle; 2. a filtering chamber; 3. a crystallization kettle; 4. a collection box; 5. a feed inlet; 6. a mounting box; 7. a stirring motor; 8. a stirring rod; 9. a control valve; 10. a first fixing plate; 11. a first motor; 12. a disc; 13. a movable sleeve; 14. a movable plate; 15. a first stop collar; 16. a C-shaped frame; 17. a first filter plate; 18. a pump body; 19. a connecting pipe; 20. the second limit sleeve; 21. a slide plate; 22. an inclined plate; 23. a rotating shaft; 24. an eccentric wheel; 25. a synchronizing wheel; 26. a belt; 27. a second fixing plate; 28. a second motor; 29. a threaded rod; 30. an auxiliary lever; 31. a thread sleeve; 32. a connecting rod; 33. a scraper; 34. a first gear; 35. a third fixing plate; 36. a third motor; 37. a second gear; 38. and a second filter plate.
Detailed Description
The objects, technical solutions and advantages of the present application will become more apparent by the following detailed description of the present application with reference to the accompanying drawings. It should be understood that the description is only illustrative and is not intended to limit the scope of the application. In addition, in the following description, descriptions of well-known structures and techniques are omitted so as not to unnecessarily obscure the present application.
As shown in fig. 1-5, the nicotinamide mononucleotide cooling crystallization device provided by the application comprises a heating kettle 1, a crystallization kettle 3, a filtering structure, a slow flow structure and a scraping structure, and is characterized in that a feeding port 5 is arranged at the left upper end of the heating kettle 1, a mounting box 6 is arranged in the middle of the upper end of the heating kettle 1, a stirring motor 7 is arranged in the mounting box 6, a stirring rod 8 is arranged at the top end inside the heating kettle 1, the upper end of the stirring rod 8 penetrates through the heating kettle 1 and is connected with the output end of the stirring motor 7, a plurality of stirring blades are arranged on the stirring rod 8, a control valve 9 is arranged in the middle of the lower end of the heating kettle 1, the filtering structure is arranged at the lower side of the control valve 9, the crystallization kettle 3 is arranged on the right side of the heating kettle 1, the slow flow structure is arranged at the upper side inside the crystallization kettle 3, a scraping structure is arranged at the left lower side of the crystallization kettle 3, a collecting box 4 is arranged at the right side of the crystallization kettle 3, a feeding box is arranged at the lower side of the right end of the crystallization kettle 3, the left end upper side of the collecting box 4 is provided with a groove, and the discharging groove is adapted to the groove.
In an alternative embodiment, the filter structure includes filter chamber 2, first fixed plate 10, first motor 11, disc 12, movable sleeve 13, fly leaf 14, first stop collar 15, C type frame 16 and first filter 17, control valve 9 lower extreme is connected with the discharging pipe, and the discharging pipe lower extreme is provided with filter chamber 2, and filter chamber 2 front end is provided with the chamber door, both ends all are provided with first fixed plate 10 about filter chamber 2, and first fixed plate 10 upper end is provided with first motor 11, and the output of two first motors 11 all runs through to filter chamber 2 inside fixedly connected with disc 12, and two discs 12 are close to one end mutually and all are provided with protruding post, and protruding post outside is provided with movable sleeve 13, filter chamber 2 inside both ends all are provided with first stop collar 15 about, and the inside sliding connection of first stop collar 15 has movable plate 14, and movable plate 14 lower extreme is connected with movable sleeve 13, and the movable plate 14 upper end is provided with C type frame 16, and two C type frames 16 symmetry, two C type frame 16 inside are provided with first filter 17, carry out the quality of single crystal 17 and sieve after the inside crystallization of filter, and the quality of solution is improved.
In an alternative embodiment, the slow flow structure includes second stop collar 20, slide 21, inclined plate 22, axis of rotation 23 and eccentric wheel 24, both ends all are provided with two second stop collar 20 and axis of rotation 23 about crystallization kettle 3 inside, and axis of rotation 23 is located second stop collar 20 downside, and two sets of second stop collar 20 horizontal position on left side are higher than two sets of second stop collar 20 on right side, and second stop collar 20 inside sliding connection has slide 21, and slide 21 upper end is provided with inclined plate 22, be provided with eccentric wheel 24 on axis of rotation 23, crystallization kettle 3 both ends all are provided with second fixed plate 27 about, and the horizontal position of left side second fixed plate 27 is higher than right side second fixed plate 27, and second fixed plate 27 upper end is provided with second motor 28, and a plurality of axis of rotation 23 all run through to crystallization kettle 3 outside and be provided with synchronizing wheel 25, and be provided with belt 26 between two synchronizing wheels 25 on the same side, and two synchronizing wheel 25 that are located the downside and second motor 28 export end phase of second motor 28, can reduce the crystallization kettle's efficiency in order to fully cooling down in the crystallization kettle 3 through the output of the inclined plate 22.
In an alternative embodiment, the scraping structure comprises a threaded rod 29, an auxiliary rod 30, a threaded sleeve 31, a connecting rod 32, a first gear 34, a third fixed plate 35, a third motor 36 and a second gear 37, wherein the threaded rod 29 and the auxiliary rod 30 are arranged at the lower side of the left end of the crystallization kettle 3, the auxiliary rod 30 is positioned at the upper side of the threaded rod 29, the threaded sleeve 31 is connected to the threaded rod 29 in a threaded manner, the connecting rod 32 is arranged at the upper side of the right end of the threaded sleeve 31, the first gear 34 is arranged at the right side of the outer part of the threaded rod 29, the third fixed plate 35 is arranged at the left end of the crystallization kettle 3 and positioned at the lower side of the first gear 34, the third motor 36 is arranged at the upper end of the third fixed plate 35, the second gear 37 is arranged at the output end of the third motor 36, the first gear 34 is meshed with the second gear 37, a chute matched with the connecting rod 32 is formed at the lower side of the left end of the crystallization kettle 3, the right end of the connecting rod 32 penetrates through the chute to be provided with the scraper 33, the lower side of the crystallization kettle 3 is provided with a second filter plate 38, and the middle of the lower end of the crystallization kettle 3 is provided with a valve.
In an alternative embodiment, a connecting pipe 19 is disposed at the lower side of the right end of the filtering chamber 2, a mounting plate is disposed at the upper side of the left end of the crystallization kettle 3, a pump body 18 is disposed at the upper end of the mounting plate, an inlet end of the pump body 18 is communicated with the connecting pipe 19, an outlet end of the connecting pipe 19 is communicated with the crystallization kettle 3, and an outlet end of the connecting pipe 19 penetrates into the crystallization kettle 3.
In an alternative embodiment, the first motor 11, the stirring motor 7, the second motor 28, and the third motor 36 are all electrically connected to an external power source and an external singlechip, and the model of the singlechip is STM32.
The working principle of the application is as follows: when in use, materials are put into the heating kettle 1 through the feed inlet 5, the materials are heated through the heating kettle 1, so that the dissolution amount of the materials is improved, crystals are easier to separate out, meanwhile, the stirring motor 7 is started, the stirring rod 8 is driven to rotate through the stirring motor 7, the dissolution speed of the materials is accelerated through the rotation of a plurality of stirring blades, the production efficiency of the device is improved, the dissolved solution can be conveyed into the filter chamber 2 through the control valve 9, the solution enters the filter chamber 2 and falls on the first filter plate 17, impurities in the solution to be crystallized are screened through the first filter plate 17, the quality and purity of the subsequent nicotinamide mononucleotide crystals are improved, when the solution is filtered, a worker can start the first motor 11, the disc 12 is driven to rotate through the first motor 11, the movable plate 14 is driven to move up and down in the first limit sleeve 15 by means of the mutual matching of the protruding columns on the disc 12 and the movable sleeve 13, the C-shaped frame 16 and the first filter plate 17 are driven to move up and down in a reciprocating manner, the filtering speed of the solution is accelerated by the back and forth movement of the first filter plate 17, the production efficiency of the device is further improved, the first filter plate 17 can be taken out from the C-shaped frame 16 of the filter chamber 2 by opening the box door, the staff can conveniently clean the impurities on the first filter plate 17 in time, the impurities on the first filter plate 17 are prevented from being too much to block and influence the subsequent filtering of the solution, the filtered solution can be conveyed into the crystallization kettle 3 through the pump body 18 and the connecting pipe 19, the solution is cooled through the crystallization kettle 3, the crystallization is completed, the solution enters the crystallization kettle 3 and can fall on a plurality of inclined plates 22 in sequence, through the flow of solution on inclined plate 22 come effectual reduction solution's velocity of flow, make solution can fully react in crystallization kettle 3, improve crystallization kettle 3 internal solution's cooling efficiency, make solution can more abundant precipitation crystal, then the staff can start second motor 28, drive adjacent synchronizing wheel 25 through second motor 28 and rotate, with the help of synchronizing wheel 25 and belt 26's mutually support, drive rotation axis 23 and rotate, and then drive a plurality of eccentric wheels 24 and rotate, can upwards promote slide plate 21 in second stop collar 20 at eccentric wheel 24 pivoted in-process, and then drive inclined plate 22 and reciprocate from top to bottom, in inclined plate 22's back and forth shake, drive a small amount of solution that adheres on inclined plate 22 and the crystal of precipitation downwardly moving, reduce extravagant, filter crystal and solution through the setting of second filter plate 38, thereby intercept the crystal that will separate on second filter plate 38, and the solution accessible that has the valve is equipped with drain tube of valve is discharged, after crystallization finishes, the staff can start third motor 36 through third motor 36, drive through third gear 36 and carry out the rotation of second gear 37 and drive the second filter plate 37 and carry out the motion to the inside of the connecting rod 32 at the right side of the groove 32, and drive the groove 32 to the inside of the connecting rod 32 at the side of the groove 32 that rotates, the groove 32 is driven to the inside of the groove 32 to the groove is moved to the groove.
It is to be understood that the above-described embodiments of the present application are intended to be illustrative or explanatory of the principles of the application, and are not restrictive of the application. Accordingly, any modification, equivalent replacement, improvement, etc. made without departing from the spirit and scope of the present application should be included in the scope of the present application. Furthermore, the appended claims are intended to cover all such changes and modifications that fall within the scope and boundary of the appended claims, or equivalents of such scope and boundary.
Claims (10)
1. The utility model provides a nicotinamide mononucleotide cooling crystallization device, includes heating cauldron (1), crystallization kettle (3), filtration, slow flow structure and scrapes the material structure, a serial communication port, heating cauldron (1) lower extreme middle part is provided with control valve (9), and control valve (9) downside is provided with filtration, and heating cauldron (1) right side is provided with crystallization kettle (3), and crystallization kettle (3) inside upside is provided with slow flow structure, and crystallization kettle (3) left side downside is provided with scrapes the material structure, and crystallization kettle (3) right side is provided with collecting box (4).
2. The nicotinamide mononucleotide cooling crystallization device according to claim 1, wherein the filtering structure comprises a filtering chamber (2), a first fixed plate (10), a first motor (11), a disc (12), a movable sleeve (13), a movable plate (14), a first limiting sleeve (15), a C-shaped frame (16) and a first filter plate (17), the lower end of the control valve (9) is connected with a discharging pipe, the lower end of the discharging pipe is provided with the filtering chamber (2), the front end of the filtering chamber (2) is provided with a box door, the left end and the right end of the filtering chamber (2) are respectively provided with the first fixed plate (10), the upper end of the first fixed plate (10) is provided with the first motor (11), the output ends of the two first motors (11) respectively penetrate through the disc (12) fixedly connected with the inside of the filtering chamber (2), protruding columns are respectively arranged at the positions close to one ends of the two discs (12), the outside of the protruding columns are respectively provided with the movable sleeve (13), the left end and the right end of the inside of the filtering chamber (2) is respectively provided with the first limiting sleeve (15), the inner sliding plates (15) are respectively connected with the two movable sleeves (14) and the upper ends and the two discs (16) are respectively connected with the upper ends and the two movable sleeves (16) symmetrically arranged at the two ends of the upper ends of the movable sleeve (16), the two C-shaped frames (16) are internally provided with a first filter plate (17).
3. The nicotinamide mononucleotide cooling crystallization device according to claim 1, wherein the slow flow structure comprises a second limit sleeve (20), a slide plate (21), an inclined plate (22), a rotating shaft (23) and an eccentric wheel (24), two second limit sleeves (20) and the rotating shaft (23) are arranged at the left end and the right end of the inside of the crystallization kettle (3), the rotating shaft (23) is positioned at the lower side of the second limit sleeve (20), two groups of second limit sleeves (20) at the left side are higher than two groups of second limit sleeves (20) at the right side in horizontal position, the slide plate (21) is connected inside the second limit sleeve (20) in a sliding mode, the inclined plate (22) is arranged at the upper end of the slide plate (21), and the eccentric wheel (24) is arranged on the rotating shaft (23).
4. The nicotinamide mononucleotide cooling crystallization device according to claim 1, wherein the scraping structure comprises a threaded rod (29), an auxiliary rod (30), a threaded sleeve (31), a connecting rod (32), a first gear (34), a third fixing plate (35), a third motor (36) and a second gear (37), the threaded rod (29) and the auxiliary rod (30) are arranged at the lower side of the left end of the crystallization kettle (3), the auxiliary rod (30) is arranged at the upper side of the threaded rod (29), the threaded sleeve (31) is in threaded connection with the threaded rod (29), the connecting rod (32) is arranged at the upper side of the right end of the threaded sleeve (31), the first gear (34) is arranged at the right side of the outer part of the threaded rod (29), the left end of the crystallization kettle (3) is provided with the third fixing plate (35) at the lower side of the first gear (34), the upper end of the third fixing plate (35) is provided with the third motor (36), the second gear (37) is arranged at the output end of the third motor (36), and the first gear (34) is in meshed connection with the second gear (37).
5. The nicotinamide mononucleotide cooling crystallization device according to claim 1, wherein a feed inlet (5) is formed in the left upper end of the heating kettle (1), a mounting box (6) is arranged in the middle of the upper end of the heating kettle (1), a stirring motor (7) is arranged in the mounting box (6), a stirring rod (8) is arranged at the top end inside the heating kettle (1), the upper end of the stirring rod (8) penetrates through the heating kettle (1) to be connected with the output end of the stirring motor (7), and a plurality of stirring blades are arranged on the stirring rod (8).
6. The nicotinamide mononucleotide cooling crystallization device according to claim 2, wherein a connecting pipe (19) is arranged at the lower side of the right end of the filtering chamber (2), a mounting plate is arranged at the upper side of the left end of the crystallization kettle (3), a pump body (18) is arranged at the upper end of the mounting plate, the inlet end of the pump body (18) is communicated with the connecting pipe (19), the outlet end of the connecting pipe (19) is communicated with the crystallization kettle (3), and the outlet end of the connecting pipe (19) penetrates into the crystallization kettle (3).
7. The nicotinamide mononucleotide cooling crystallization device according to claim 1, wherein the left end and the right end of the crystallization kettle (3) are respectively provided with a second fixing plate (27), the horizontal position of the left second fixing plate (27) is higher than that of the right second fixing plate (27), the upper end of the second fixing plate (27) is provided with a second motor (28), a plurality of rotating shafts (23) penetrate through the crystallization kettle (3) to be provided with synchronous wheels (25), a belt (26) is arranged between the two synchronous wheels (25) on the same side, and the two synchronous wheels (25) on the lower side are connected with the output end of the second motor (28).
8. The nicotinamide mononucleotide cooling crystallization device according to claim 1, wherein a chute matched with the connecting rod (32) is formed in the lower side of the left end of the crystallization kettle (3), a scraper (33) is arranged at the right end of the connecting rod (32) penetrating through the chute, a second filter plate (38) is arranged in the lower side of the inside of the crystallization kettle (3), and a liquid discharge pipe with a valve is arranged in the middle of the lower end of the crystallization kettle (3).
9. The nicotinamide mononucleotide cooling crystallization device according to claim 1, wherein a discharge groove is formed in the lower side of the right end of the crystallization kettle (3), a feed groove is formed in the upper side of the left end of the collecting box (4), and the discharge groove is matched with the feed groove.
10. The nicotinamide mononucleotide cooling crystallization device according to claim 2, wherein the first motor (11), the stirring motor (7), the second motor (28) and the third motor (36) are electrically connected with an external power supply and an external singlechip, and the model of the singlechip is STM32.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202311278350.XA CN117224992A (en) | 2023-10-07 | 2023-10-07 | A kind of nicotinamide mononucleotide cooling crystallization device |
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| CN202311278350.XA CN117224992A (en) | 2023-10-07 | 2023-10-07 | A kind of nicotinamide mononucleotide cooling crystallization device |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN119139716A (en) * | 2024-11-14 | 2024-12-17 | 潍坊新绿化工有限公司 | Separation and purification equipment for hexachloroethane recovery |
| CN120960812A (en) * | 2025-08-12 | 2025-11-18 | 东营联合石化有限责任公司 | Efficient energy-saving paraxylene production device |
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| CN215613229U (en) * | 2021-09-18 | 2022-01-25 | 吉林百奥生物科技有限公司 | Nicotinamide mononucleotide screening plant |
| CN215609462U (en) * | 2021-09-18 | 2022-01-25 | 吉林百奥生物科技有限公司 | A recrystallization device for production of nicotinamide mononucleotide |
| CN217909041U (en) * | 2022-08-19 | 2022-11-29 | 吉林百奥生物科技有限公司 | Beta-nicotinamide mononucleotide's recrystallization device |
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| CN208049440U (en) * | 2018-02-28 | 2018-11-06 | 江西拓泓新材料有限公司 | A kind of potassium floutaramite crystallization cooling device |
| CN209790919U (en) * | 2019-03-12 | 2019-12-17 | 德庆县泰利新材料有限公司 | Cooling crystallization tower |
| CN215613229U (en) * | 2021-09-18 | 2022-01-25 | 吉林百奥生物科技有限公司 | Nicotinamide mononucleotide screening plant |
| CN215609462U (en) * | 2021-09-18 | 2022-01-25 | 吉林百奥生物科技有限公司 | A recrystallization device for production of nicotinamide mononucleotide |
| CN217909041U (en) * | 2022-08-19 | 2022-11-29 | 吉林百奥生物科技有限公司 | Beta-nicotinamide mononucleotide's recrystallization device |
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| CN119139716A (en) * | 2024-11-14 | 2024-12-17 | 潍坊新绿化工有限公司 | Separation and purification equipment for hexachloroethane recovery |
| CN120960812A (en) * | 2025-08-12 | 2025-11-18 | 东营联合石化有限责任公司 | Efficient energy-saving paraxylene production device |
| CN120960812B (en) * | 2025-08-12 | 2026-03-24 | 东营联合石化有限责任公司 | Efficient energy-saving paraxylene production device |
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