CN116746987A - Cutting and collecting catheter and intravascular calcified plaque removing device - Google Patents

Abstract

The invention discloses a cutting and collecting catheter and an intravascular calcified plaque removing device, and relates to the technical field of medical instruments. The cutting and collecting catheter comprises a tube body, a cutting member and a collecting member; the tube body is provided with an exposure opening; the cutting component is rotatably arranged in the tube body and positioned at the exposed opening, and is used for rotatably cutting the calcified plaque in the blood vessel; the collecting component is integrally formed with the tube body or arranged in the tube body and is used for collecting calcified plaque fragments generated in the cutting process. The invention provides a cutting and collecting catheter and an intravascular calcified plaque removing device, which realize the collection of calcified plaque fragments while removing intravascular calcified plaque so as to avoid the calcified plaque fragments from remaining in blood vessels in a body and greatly reduce the risk of cutting through the blood vessels.

Description

Cutting and collection catheters and intravascular calcified plaque removal devices

Technical field

The present invention relates to the technical field of medical devices, and in particular to a cutting and collecting catheter and an intravascular calcified plaque removal device.

Background technique

Calcified plaque is a substance harmful to the human body caused by the deposition of fat, thrombus, connective tissue and calcium carbonate on the inner wall of blood vessels. The presence of calcified plaque can narrow the lumen of the blood vessel and impede blood flow. In severe cases, it can cause organ damage. Insufficient blood supply, plaque rupture may even block blood vessels, causing acute ischemia of the patient's organs. Therefore, it is necessary to remove calcified plaque in blood vessels.

The catheter of the existing calcified plaque removal device includes a tube body and a cutter installed in the tube body. The cutter is connected to a motor and is driven by the motor to rotate and cut calcified plaques in human blood vessels. However, the catheter of this calcified plaque removal device generates a large amount of fragments during the removal of calcified plaques without any treatment. The calcified plaque fragments remain in the blood vessels and may form embolisms and cause problems.

Contents of the invention

The main purpose of the present invention is to provide a cutting and collecting catheter and an intravascular calcified plaque removal device, which aims to collect calcified plaque fragments while removing intravascular calcified plaque, so as to avoid calcified plaque fragments remaining in blood vessels in the body. middle.

In order to achieve the above object, the present invention proposes a cutting and collecting catheter, including:

The pipe body is provided with an exposure port;

A cutting component, which is rotatably installed in the tube body and located at the exposure port, and is used to rotate and cut intravascular calcified plaque; and

A collection component is integrally formed with or provided in the tube body. The collection component is used to collect calcified plaque fragments generated during the cutting process.

Optionally, the cutting component includes a cutter holder and a cutter head. The cutter holder is suitable for driving connection with the driving assembly through a transmission shaft. The cutter holder is provided with a protruding column, and the cutter head corresponds to the protruding column. is provided with a matching mounting hole, and the protruding column is inserted into the mounting hole and fixed by welding or bonding.

Optionally, the cutting edge of the cutter head is deflected toward the axis by an angle α so that the cutting edge of the cutter head is parallel to the blood vessel wall of the human body.

Optionally, the cutting part further includes a cutter parking part and/or a cutter adjustment part. The cutter parking part is provided inside the proximal end of the tube body and is used for docking the cutting part when it is working. , the cutter adjustment piece is partially inserted inside the proximal end of the tube body and used to resist the collection component when the cutting component is working.

Optionally, the collection component includes a skeleton, a first guide wire cavity and a first developing member, and the skeleton, the first guide wire cavity and the first developing member are laminated and heat-shrunk or injection molded to form a collecting member. The main body of the tube, the skeleton is hollow, the first guide wire cavity is formed with a first guide wire cavity for the guide wire to pass through, the first developing member is arranged in the first guide wire cavity, so The first developing member is used to develop under detection by imaging equipment to mark the location of the collection component after the cutting and collection catheter enters the human body; and/or

The collecting component has a curved section, and the curved section is used to bring the cutting component close to the side of the blood vessel wall where the calcified plaque is located.

Optionally, the cutting and collecting catheter further includes a tip assembly disposed at the distal end of the tube body, and the tip assembly is tapered as a whole.

Optionally, the tip assembly includes a support member, a connecting member, a second guide wire cavity and a second developing member, and the support member, the connecting member, the second guide wire cavity and the third developing member The two developing parts are laminated and heat-shrunk or injection-molded to form a pointed body, the support member is connected to the collecting component, the connecting piece is embedded in the pointed body, and the second guide wire cavity is provided with There is a second guidewire lumen for the guidewire to pass through, and the second developing member is provided in the second guidewire cavity. The second developing member is used for developing under detection by an imaging device to perform the cutting operation. After the collection catheter enters the human body, the position of the pointed assembly is marked.

In order to achieve the above object, the present invention also proposes an intravascular calcified plaque removal device, including:

drive components;

a delivery catheter with a proximal end secured to the drive assembly; and

The cutting and collecting catheter as described above is fixed on the distal end of the delivery catheter and is drivingly connected to the driving assembly. The driving assembly is used to drive the cutting component of the cutting and collecting catheter to rotate to cut intravascular calcification. Plaque; the cutting and collection catheter includes:

The pipe body is provided with an exposure port;

A cutting component, which is rotatably installed in the tube body and located at the exposure port, and is used to rotate and cut intravascular calcified plaque; and

A collection component is integrally formed with the tube body or is provided at the distal end of the tube body. The collection component is used to collect calcified plaque fragments generated during the cutting process.

Optionally, the delivery conduit includes a spiral torsion tube, a leak-proof membrane and a metal braided mesh, and the spiral torsion tube, the leak-proof membrane and the metal braided mesh are laminated and heat-shrunk or injection-molded to form a catheter body. ;and / or

The delivery catheter has a fixed elbow section that is adapted to abut against the blood vessel wall and is used to provide supporting force for the cutting component so that it is close to the side of the blood vessel wall where the calcified plaque is located.

Optionally, the driving assembly is also used to control the blade of the cutting component to lift to a preset height when cutting calcification plaques, and the preset height is suitable to be smaller than the blood vessel wall thickness.

In the technical solution of the present invention, the cutting and collecting catheter includes a tube body, a cutting part and a collecting part; the tube body is provided with an exposure port; the cutting part is rotatably arranged in the tube body and located at the exposure port, and the cutting part is used to rotate and cut blood vessels Internal calcified plaque; the collection component is integrally formed with the tube body or is located at the distal end of the tube body, and the collection component is used to collect calcified plaque fragments generated during the cutting process. In this way, by setting the cutting part to rotate and cut the calcified plaque in the blood vessel, and at the same time, the collecting part collects the calcified plaque fragments generated during the cutting process, which effectively removes the calcified plaque in the blood vessel and prevents the calcified plaque fragments from remaining in the blood vessels in the body.

Description of the drawings

In order to explain the embodiments of the present invention or the technical solutions in the prior art more clearly, the drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings in the following description are only These are some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on the structures shown in these drawings without exerting creative efforts.

Figure 1 is a schematic structural diagram of an embodiment of the cutting and collecting catheter of the present invention;

Figure 2 is a detailed structural view of an embodiment of the cutting and collection catheter of the present invention;

Figure 3 is a schematic diagram of removing calcified plaques in one embodiment of the cutting and collecting catheter of the present invention;

Figure 4 is a schematic structural diagram of the curved section of the collection component in one embodiment of the cutting and collection catheter of the present invention;

Figure 5 is a schematic diagram of the elevation height and blade angle of the cutter head when the cutting and collecting catheter is in working state according to an embodiment of the present invention;

Figure 6 is a schematic structural diagram of the cutting component in one embodiment of the cutting and collecting catheter of the present invention;

Figure 7 is an exploded view of the cutting component in one embodiment of the cutting and collecting catheter of the present invention;

Figure 8 is a schematic structural diagram of an embodiment of the intravascular calcified plaque removal device of the present invention;

Figure 9 is a schematic structural diagram of a delivery catheter in an embodiment of the intravascular calcified plaque removal device of the present invention.

Explanation of reference numbers:

100. Cutting and collecting catheter; 200. Delivery catheter; 300. Driving component; 10. Tube body; 20. Cutting component; 30. Collection component; 40. Tip assembly; 10a. Exposure port; 101. Blood vessel; 102. Calcification Plaque; 21. Knife holder; 22. Cutter head; 23. Drive shaft; 211. Boss; 22a. Mounting hole; 24. Cutter parking piece; 25. Cutter adjustment piece; 31. Skeleton; 32. First Guide wire cavity; 33. First developing member; 310. Collection tube main body; 41. Support member; 42. Connector; 43. Second guide wire cavity; 44. Second developing member; 410. Tip body; 210. Spiral torque tube; 220. Leak-proof membrane; 230. Metal braided mesh; 240. Conduit main body; 301. Bend section; 201. Fixed bend section.

The realization of the purpose, functional features and advantages of the present invention will be further described with reference to the embodiments and the accompanying drawings.

Detailed ways

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without exerting creative efforts fall within the scope of protection of the present invention.

It should be noted that all directional indications (such as up, down, left, right, front, back...) in the embodiment of the present invention are only used to explain the relationship between components in a specific posture (as shown in the drawings). Relative positional relationship, movement conditions, etc., if the specific posture changes, the directional indication will also change accordingly.

In addition, descriptions involving "first", "second", etc. in the present invention are for descriptive purposes only and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of indicated technical features. Therefore, features defined as "first" and "second" may explicitly or implicitly include at least one of these features. In addition, the meaning of "and/or" appearing in the entire text is to include three parallel plans. Taking "A and/or B" as an example, it includes plan A, or plan B, or a plan that satisfies both A and B at the same time. In addition, the technical solutions in various embodiments can be combined with each other, but it must be based on the realization by those of ordinary skill in the art. When the combination of technical solutions is contradictory or cannot be realized, it should be considered that such a combination of technical solutions does not exist. , nor within the protection scope required by the present invention.

The present invention proposes a cutting and collecting catheter, which can be used as an intravascular calcified plaque removal device or other sclerosis removal device, and is not limited here.

Referring to Figures 1 to 3, in one embodiment of the present invention, the cutting and collecting catheter 100 includes a tube body 10, a cutting part 20 and a collecting part 30; the tube body 10 is provided with an exposure opening 10a; the cutting part 20 is rotatably arranged on the tube. Inside the body 10 and located at the exposure port 10a, the cutting component 20 is used to rotate and cut the calcified plaque 102 in the blood vessel 101; the collection component 30 is integrally formed with the tube body 10 or is located inside the tube body 10, and the collection component 30 is used to collect the cutting process. Calcified plaque fragments produced in.

In this embodiment, the tube body 10 can be made of medical polymer material, which can be formed by the collection component 30 in a process such as lamination and heat shrinkage or injection molding, or can be a separate component, and the details are not limited.

The cutting component 20 may be a rotary cutter, and the specific structure is not limited here. The collection component 30 can be in the shape of a tube, especially a hollow tubular structure. It can be a single component that is assembled at the front end of the cutting component 20 in the tube body 10 by bonding or welding, or it can be an integrally formed structure with the tube body 10. No limit here.

It can be understood that the present invention effectively removes the calcified plaque 102 in the blood vessel 101 by arranging the cutting part 20 to rotate and cut the calcified plaque 102 in the blood vessel 101, and at the same time the collecting part 30 collects the calcified plaque fragments generated during the cutting process, and avoids Calcified plaque fragments remain in blood vessels 101 in the body.

In order to improve the convenience of assembling the cutting component 20 , mainly referring to FIGS. 5 to 7 , in one embodiment, the cutting component 20 may include a cutter base 21 and a cutter head 22 . The cutter base 21 is adapted to be connected to the driving assembly 300 through the transmission shaft 23 Driving connection, the tool base 21 is provided with a protruding post 211, and the cutter head 22 is provided with a matching mounting hole 22a at a position corresponding to the protruding post 211. The protruding post 211 is inserted into the mounting hole 22a and is welded or bonded. The way is fixed.

In this embodiment, the cutting component 20 is divided into a knife seat 21 and a knife head 22, which can reduce the processing difficulty of the cutting component 20. Among them, the cutter head 22 can be made of tungsten steel or other hard alloy materials to increase the blade hardness.

Preferably, as shown in FIG. 7 , the protruding pillar 211 can be configured as a flat square pillar, and the corresponding mounting hole 22a can be configured as a square hole. In this way, the tool base 21 and the tool head 22 can be assembled through the square pillar and the square hole. Assembling them into one body by welding or bonding can effectively improve the torsional strength of the cutter head 22 during the rotation of the cutting component 20 and prevent the cutter head 22 from falling off easily.

Further, with reference to FIGS. 3 , 5 and 6 , the blade of the cutter head 22 can be deflected by an angle α toward the axis, so that the blade of the cutter head 22 is parallel to the wall of the human blood vessel 101 . Optionally, the cutting edge of the cutter head 22 can be deflected toward the axis by 0° to 60°. In this way, when the cutter head 22 is in the working state, the blade of the cutter head 22 is theoretically parallel to the wall of the blood vessel 101 and the collection bag, which can effectively reduce the risk of the blood vessel 101 cutting through.

In order to improve the stability of the operation of the cutting part 20, with reference to Figures 1 to 5, in one embodiment, the cutting part 20 may also include a cutter parking part 24 and a cutter adjustment part 25. The cutter parking part 24 is provided on the pipe body. The proximal end of the tube body 10 is used for stopping the cutting component 20 when it is working. The cutter adjustment member 25 is partially inserted into the proximal end of the tube body 10 and is used to resist the collection component 30 when the cutting component 20 is working.

As shown in Figures 1 to 5 and 8, when starting the resection, the driving assembly 300 of the intravascular calcified plaque removal device is started to lift the cutting component 20 from the exposure port 10a and extend out of the tube body 10, The cutting component 20 then rotates to remove the calcified plaque 102. At this time, the inner side of the cutting component 20 rests on the cutter parking component 24 to maintain the lifted state.

Mainly referring to Figure 5, when the cutting part 20 is in working condition, the skeleton 31 of the collection part 30 is pressed against the cutter adjustment member 25, which can increase the stability of the cutter head 22 during operation and reduce the number of cuts around the cutter head 22 or the cutter head 22. The vibration of the parts further reduces the risk of the blood vessel 101 cutting through.

Referring to FIGS. 1 and 2 , in one embodiment, the collecting component 30 may include a frame 31 , a first guidewire cavity 32 and a first developing member 33 . The frame 31 , the first guidewire cavity 32 and the first developing member 33 33 The main body 310 of the collection tube is formed by lamination, heat shrinkage or injection molding. The skeleton 31 is hollow. The first guide wire cavity 32 forms a first guide wire cavity for the guide wire to pass through. The first developing member 33 is provided with In the first guidewire cavity 32, the first developing member 33 is used to develop under detection by imaging equipment to mark the position of the collection component 30 after the cutting and collection catheter 100 enters the human body.

In this embodiment, the skeleton 31 , the first guide wire cavity 32 and the first developing member 33 are fixed together through polymer material lamination and heat shrinkage or plastic injection molding to form the collection tube main body 310 . Among them, the skeleton 31 can be a hollow stainless steel tube or a nickel-titanium tube made by laser cutting or other processes. The purpose is to reduce the rigidity of the collection component 30 and increase its flexibility to facilitate passage of the blood vessel 101 and further reduce damage to the blood vessel 101.

Referring mainly to Figure 4, in one embodiment, the collection component 30 is provided with a curved section 301. The curved section 301 is used to bring the cutting component 20 close to the wall of the blood vessel 101 where the calcified plaque 102 is located, so as to lift and remove the calcified plaque 102. Effect.

In this embodiment, the curved section 301 can be disposed on the back side of the exposure opening 10a, or can be disposed at other locations of the collection component 30, such as the hollow frame 31, which is not limited thereto.

In order to facilitate the insertion of the catheter into the blood vessel 101 and reduce damage to the blood vessel 101, referring to Figures 1 and 2, in one embodiment, the cutting and collection catheter 100 may also include a tip assembly disposed at the distal end of the tube body 10 40. The pointed assembly 40 is tapered as a whole.

In this embodiment, the tip assembly 40 may include a support member 41, a connecting member 42, a second guide wire cavity 43 and a second developing member 44. The support member 41, the connecting member 42, the second guide wire cavity 43 and the second developing member 44 are The two developing parts 44 are laminated and heat-shrunk or injection molded to form the tip body 410. The support member 41 is connected to the collection part 30. The connecting piece 42 is embedded in the tip body 410. The second guide wire cavity 43 is provided with The second guide wire lumen for the guide wire to pass through, the second developing member 44 is provided in the second guide wire cavity 43, and the second developing member 44 is used to develop under detection by the imaging device to ensure that the cutting and collecting catheter 100 enters the second guide wire lumen. The position of the tip assembly 40 is marked behind the human body.

In this embodiment, the support member 41 , the connecting member 42 , the second guide wire cavity 43 and the second developing member 44 are fixed together through processes such as polymer material lamination and heat shrinkage or overcoating injection molding to form the tip body 410 . Among them, the connector 42 can increase the connection strength between the polymer material and the support 41 after lamination, heat shrinkage or overmolding. The connector 42 can be a spring or a part with uneven surfaces to increase the connection strength between the polymer material and the support 41 . connection strength. The support member 41 and the collection member 30 can be connected through processes such as welding, mechanical slotting, bonding, lamination and heat shrinkage.

The present invention also proposes an intravascular calcified plaque removal device. Refer to Figure 8. The intravascular calcified plaque removal device includes a cutting and collecting catheter 100. The specific structure of the cutting and collecting catheter 100 refers to the above embodiment. Since the present invention The proposed intravascular calcified plaque removal device includes all solutions of all embodiments of the above-mentioned cutting and collecting catheter 100. Therefore, it has at least the same technical effect as the above-mentioned cutting and collecting catheter 100, which will not be described one by one here.

Referring mainly to Figures 3 and 8, in one embodiment of the present invention, the intravascular calcified plaque removal device includes a cutting and collection catheter 100, a delivery catheter 200 and a driving assembly 300; the proximal end of the delivery catheter 200 is fixed on the driving assembly 300 Upper; the cutting and collecting catheter 100 is fixed on the distal end of the delivery catheter 200 and is drivingly connected with the driving assembly 300. The driving assembly 300 is used to drive the cutting component 20 of the cutting and collecting catheter 100 to rotate to cut the calcified plaque 102 in the blood vessel 101.

In this embodiment, the driving assembly 300 may include a motor, a battery, a circuit, a switch, a housing and other components. The battery provides power for the motor. With reference to Figures 2 and 8, the output shaft of the motor is fixed to the transmission shaft 23 connected to the cutting component 20. are connected together, thereby transmitting the rotation of the motor to the cutting component 20 through the transmission shaft 23, thereby realizing the rotation of the cutting component 20. Among them, the torque transmission ratio of the transmission shaft 23 can be 1:1, which is not limited here.

In addition, the cutting and collecting catheter 100 and the delivery catheter 200 at the distal end can be treated with hydrophilic coating to improve the passage of the catheter inside the blood vessel 101 .

Referring to FIG. 9 , in one embodiment, the delivery catheter 200 may include a spiral torque tube 210 , a leak-proof membrane 220 and a metal braid 230 . The spiral torque tube 210 , the leak-proof membrane 220 and the metal braid 230 are laminated by polymer materials. They are fixed together by processes such as heat shrinking or injection molding to form the main body 240 of the conduit, in which the spiral torque tube 210, the leak-proof membrane 220 and the metal braid 230 are sequentially distributed from the inside to the outside.

Among them, the anti-leakage membrane 220 can be made of PTFE or other materials, which is not limited here.

As shown in FIG. 3 , the delivery catheter 200 is provided with a fixed elbow section 201 . The fixed elbow section 201 is adapted to abut against the wall of the blood vessel 101 and is used to provide supporting force for the cutting component 20 so that it can be close to the calcified plaque 102 . The wall of blood vessel 101 at. That is, a section of the delivery catheter 200 can be set in a fixed curved shape, thereby providing the cutting component 20 with good wall-adhering ability during operation, and the cutting component 20 can more easily adhere to the calcified plaque 102 to achieve a good cutting effect. Preferably, the curvature of the fixed elbow section 201 can be 30° to 90°, and it can be an elbow made of a fixed-shaped flexible material.

Referring to FIG. 5 , in one embodiment, the driving assembly 300 can also be used to control the blade of the cutting component 20 to lift a preset height h when cutting calcified plaques, and the preset height h is suitable to be smaller than the wall thickness of the blood vessel 101 . Optionally, the preset height h can be 0~1mm.

As shown in FIG. 1 , the intravascular calcified plaque removal device is in an inoperative state. At this time, the cutting component 20 is inside the collection component 30 and the power switch of the driving component 300 is in a closed state. During the operation, the cutting and collecting catheter 100 at the front end of the device is inserted through the designated blood vessel 101 of the human body, and the catheter is pushed to the patient's target diseased blood vessel 101 through the blood vessel 101 system, as shown in Figure 3, and then the driving assembly is started. 300 power switch, the cutting part 20 is docked on the cutter parking part 24, the cutting part 20 is lifted up and starts to rotate. At this time, the cutting part 20 is pushed forward to pass the target lesion of the blood vessel 101, and the calcified plaque in the blood vessel 101 is removed. Block 102 and collect it in the collection part 30 to complete the treatment of the lesion.

Furthermore, when the cutting part 20 is in the cutting state, as shown in FIG. 5 , the cutter head 22 of the cutting part 20 is raised to a certain preset height h, so that when the cutter head 22 contacts the calcified plaque 102 , the cutter head 22 can be embedded. to calcified plaque 102. In practical applications, by designing a certain preset height h, the effect of cutting calcified plaque 102 of a certain thickness can be achieved.

The present invention effectively prevents the risk of blood vessel 101 cutting through. On the one hand, by adjusting the preset height h, the value of the preset height h is smaller than the wall thickness of the blood vessel 101; on the other hand, the removal device can adjust the angle α of the blade of the cutter head 22 to make the cutter head 22 in the working state. , in theory, the blade is in a parallel state with the wall of the blood vessel 101 and the collection bag. In the working state, the blade of the blade 22 is horizontally raised to a preset height h, which avoids contact between the blade and the inner wall of the blood vessel 101.

The above are only optional embodiments of the present invention, and are not intended to limit the patent scope of the present invention. Under the inventive concept of the present invention, equivalent structural transformations can be made using the contents of the description and drawings of the present invention, or directly/indirectly. Application in other related technical fields is included in the scope of patent protection of the present invention.

Claims (10)

1. A cutting and harvesting catheter, comprising:

the tube body is provided with an exposure opening;

a cutting component rotatably arranged in the tube body and positioned at the exposed opening, wherein the cutting component is used for rotatably cutting the calcified plaque in the blood vessel; and

and the collecting component is integrally formed with the pipe body or arranged in the pipe body and is used for collecting calcified plaque fragments generated in the cutting process.

2. The cutting and collecting catheter according to claim 1, wherein the cutting member comprises a blade holder and a blade head, the blade holder is adapted to be in driving connection with the driving assembly through a transmission shaft, a convex column is arranged on the blade holder, a mounting hole adapted to the convex column is arranged on the blade head at a position corresponding to the convex column, and the convex column is inserted into the mounting hole and fixed through welding or bonding.

3. The cutting and harvesting catheter of claim 2, wherein the blade of the blade tip is deflected toward the hub by an angle α such that the blade of the blade tip is parallel to the body vessel wall.

4. The cutting and collecting catheter of claim 2, wherein the cutting member further comprises a cutter anchor member disposed within the proximal end of the tube body for resting the cutting member when in operation, and/or a cutter adjustment member partially inserted within the proximal end of the tube body for abutting the collecting member when the cutting member is in operation.

5. The cutting and collecting catheter according to claim 1, wherein the collecting member comprises a skeleton, a first guide wire cavity and a first developing member, the skeleton, the first guide wire cavity and the first developing member are encapsulated by lamination heat shrinkage or injection molding to form a collecting catheter main body, the skeleton is hollow, the first guide wire cavity is formed with a first guide wire cavity channel for a guide wire to pass through, the first developing member is arranged in the first guide wire cavity, and the first developing member is used for developing under detection of an imaging device so as to mark the position of the collecting member after the cutting and collecting catheter enters a human body; and/or

The collection member has a curved section for bringing the cutting member into close proximity with a side of the vessel wall where the calcified plaque is located.

6. The cutting and harvesting catheter of any of claims 1-5, further comprising a tip assembly disposed at a distal end of the tube body, the tip assembly being generally tapered.

7. The cutting and harvesting catheter of claim 6, wherein the tip assembly comprises a support, a connector, a second guidewire lumen and a second developing member, wherein the support, the connector, the second guidewire lumen and the second developing member are encapsulated by lamination heat shrinkage or injection molding to form a tip body, the support is connected to the harvesting member, the connector is embedded in the tip body, the second guidewire lumen is provided with a second guidewire lumen channel for a guidewire to pass through, the second developing member is provided in the second guidewire lumen, and the second developing member is used for developing under detection of an imaging device to mark the position of the tip assembly after the cutting and harvesting catheter enters a human body.

8. An intravascular calcified plaque removal apparatus comprising:

a drive assembly;

a delivery catheter, the proximal end of the delivery catheter being secured to the drive assembly; and

the cutting and harvesting catheter of any one of claims 1-7, secured to the distal end of the delivery catheter and drivingly connected to the drive assembly, the drive assembly for driving rotation of the cutting member of the cutting and harvesting catheter to cut intravascular calcified plaque.

9. The endovascular calcified plaque removal apparatus of claim 8, wherein the delivery catheter comprises a spiral torsion tube, a leak-proof membrane, and a metal mesh, the spiral torsion tube, leak-proof membrane, and metal mesh being encapsulated by lamination heat shrinkage or injection molding to form a catheter body; and/or

The delivery catheter has a fixed bend section adapted to rest against the vessel wall and to provide support for the cutting member to lie adjacent the side of the vessel wall where the calcified plaque is located.

10. The endovascular calcified plaque removal apparatus of claim 8, wherein the drive assembly is further configured to control the blade of the cutting member to raise a preset height when cutting calcified plaque, the preset height being adapted to be less than a wall thickness of a blood vessel.