CN116585922A - A pharmaceutical and chemical mixer that uses vacuum mixing technology to prevent particle settling - Google Patents

Abstract

The application discloses a pharmaceutical and chemical mixer that uses vacuum stirring technology to prevent particle settlement, including a fixed seat, a mixing drum, a machine head, a stirring shaft, a stirring blade and a cross bar. The mixing drum is used to hold granular materials; the machine head passes through The telescopic rod is movably arranged on the upper side of the fixed seat; the stirring shaft is rotated and stirred through the rotation drive; the stirring blade is rotated and arranged on the side of the stirring shaft, and the stirring blade realizes angular swing through the swing assembly; the cross bar rotates through the rotation drive. The application realizes multi-directional and full-angle particle mixing by setting the swing assembly, rotation drive and self-rotation drive, avoiding dead angle and particle settlement.

Description

A pharmaceutical and chemical mixer that uses vacuum mixing technology to prevent particle settling

technical field

The present application relates to the technical field of particle mixers, and more specifically, relates to a pharmaceutical and chemical mixer that uses vacuum stirring technology to prevent particles from settling.

Background technique

To produce high-quality products in the pharmaceutical and chemical industry, it is urgent to adopt aseptic and non-oxidative mixing technology. Stirring equipment under traditional atmospheric pressure has problems such as the introduction of a large amount of oxygen leading to oxidative deterioration of the contents, the open design causes volatilization and splash loss, direct contact with the contents increases the risk of secondary pollution, and waste gas emissions cause resource waste and pollution, which cannot meet the needs of the pharmaceutical and chemical industries. requirements. Vacuum stirring technology can carry out aseptic and non-oxidative stirring under high vacuum conditions, minimize the oxidative deterioration and secondary pollution of the contents, and realize efficient resource utilization and pollution prevention. Compared with stirring equipment under atmospheric pressure, vacuum mixer has the advantages of avoiding oxidative deterioration, no volatilization and splash loss, meeting sterility requirements, and reducing exhaust emissions, etc., and is very suitable for the pharmaceutical and chemical industry. Vacuum mixing technology can produce high-quality products, while being environmentally friendly and energy-saving, which meets the sustainable development requirements of the pharmaceutical and chemical industry, and is an inevitable trend in the development of this field. Vacuum mixers have very broad application prospects in the pharmaceutical and chemical industry, and the use of vacuum mixers for production is an important way for enterprises in this field to achieve high-quality, high-efficiency, and green development.

The prior art publication number is CN115532137A, which provides a vacuum mixer for preventing particles from settling. The vacuum mixer realizes vacuum mixing through the lifting assembly and the air outlet pipe, and then the motor drives the transmission shaft to rotate, and then drives the spiral blade, bobbin tube and stirring blade to rotate. , Two ways of direct mixing with stirring blades and mixing with helical blades to extract bottom sedimentation materials are used to prevent particles from settling and improve mixing efficiency. Although the vacuum mixer achieves a comprehensive and uniform mixing effect, it only relies on the mixing blade and the wind to mix, and there are the following problems: the mixing blade only rotates to move the particles, and the direction of force is single, so it cannot produce multi-track motion and Injecting in different directions leads to poor mixing effect, especially when there are many particles, the wind blowing effect is smaller, and it is difficult to achieve the ideal mixing effect.

To sum up, how to achieve comprehensive and uniform mixing in the case of a large number of particles has become an urgent problem to be solved.

Contents of the invention

In order to overcome a series of defects in the prior art, the purpose of this patent is to address the above problems and provide a pharmaceutical and chemical mixer that uses vacuum stirring technology to prevent particle settlement, including:

Fixing seat 1;

A mixing drum 2, which is used to hold granular materials;

The machine head 3, the machine head 3 is movably arranged on the upper side of the fixed base 1 through the telescopic rod 4;

Stirring shaft 5, described stirring shaft 5 rotates and stirs by rotating drive;

Stirring blade 6, the stirring blade 6 is rotatably arranged on the side of the stirring shaft 5, and the stirring blade 6 realizes angular swing through the swing assembly;

The crossbar 7 is driven to rotate by itself.

Optionally, the rotary drive includes a rotary box 51, and a first motor 52 is fixed inside the rotary box 51, and the output shaft of the first motor 52 extends downward through the side wall of the rotary box 51 to the outside and is connected with the stirring Axis 5 is coaxially fixedly connected.

In the above technical solution, the swing assembly and the cross bar 7 can perform revolution while completing their own actions, so that the entire inner circumference of the mixing drum 2 can be stirred, and dead ends can be avoided.

Optionally, a mechanical groove 61 is provided in the middle of the stirring shaft 5, and the swing assembly includes a crankshaft 62 that is rotatably arranged inside the mechanical groove 61, and a pull rod 63 is provided at the lower end of the crankshaft 62 through shaft rotation, and the pull rod 63 lower end is fixedly provided with hinge seat 64, is provided with pull bar 65 through pin shaft rotation between the inner wall of described hinge seat 64, and the lower end of described pull bar 65 is fixedly provided with slide block 66; The two ends of described slide block 66 respectively extend to stirring A swing rod 67 is fixedly arranged on the outside of the shaft 5, and the swing rod 67 is arranged in a symmetrical structure up and down; one end of the swing rod 67 is provided with an adapting groove 68, and the adapting groove 68 is slidingly connected with the cylindrical rod of the stirring blade 6; The above-mentioned oscillating assembly is provided with two groups in an up-and-down structure, and the two crankshafts 62 are driven to rotate through synchronous driving.

After adopting the above technical solution, the angles and motion tracks of the cross bar 7 and each stirring blade 6 can be different, and multiple force application directions can be added.

Optionally, the inner end of the circumferential rod of the stirring blade 6 is fixedly provided with a rotating block 601 arranged in an arc-shaped structure, and the outer wall of the stirring shaft 5 is provided with a rotating groove 602, and the rotating groove 602 is rotationally connected with the rotating block 601 .

After adopting the above technical solution, the stirring shaft 5 exerts forces at different angles, which further improves the mixing effect.

Optionally, the plurality of stirring blades 6 are arranged at different initial angles in the horizontal direction.

After adopting the above technical solution, while the stirring blade 6 is swinging up and down, the stirring blade 6 will produce tangential motion in different directions.

Optionally, the synchronous drive includes a worm wheel 6001 fixedly arranged on the top side of the crankshaft 62, the worm wheel 6001 is meshed with a worm 6002, and the upper and lower two worms 6002 are coaxially fixedly connected; the inner wall of the mechanical groove 61 is fixed A second motor 6003 is provided, and the output shaft of the second motor 6003 is fixedly connected with the worm 6002 coaxially. In the above technical solution, the superposition of the flow field generated by the synchronous operation of the upper and lower groups of oscillating components can not only achieve a more comprehensive and uniform rheological effect inside the slurry, effectively improve the mixing quality, but also effectively reduce the volume of the equipment.

Optionally, a stirring plate 71 is fixedly arranged on the side of the cross bar 7 , a plurality of stirring plates 71 are arranged at equal intervals in a ring shape, and multiple sets of the stirring plates 71 are arranged in the horizontal direction.

In the above technical solution, each stirring plate 71 can generate strong centrifugal force and tangential flow velocity during the rotation process to realize the impact, cutting and tumbling effects of the slurry, and the superposition of multiple stirring plates 71 can produce more powerful and The complex flow environment can effectively enhance the mixing uniformity of the slurry in each area; at the same time, the setting of multiple stirring plates 71 can achieve a more comprehensive and detailed coverage of the inner space of the container, eliminating or reducing the partial "Dead angle" realizes 360° mixing effect on the entire space; moreover, setting more stirring plates 71 can also achieve a higher linear speed at a certain speed, resulting in a stronger dynamic effect, which is beneficial to the inside of the slurry More detailed dispersion and uniformity, higher mixing quality can be obtained at lower speed, and high-efficiency mixing can be achieved.

Optionally, the side of the stirring shaft 5 is penetratingly provided with a limiting channel 701 corresponding to the sliding block 66, the limiting channel 701 communicates with the mechanical channel 61, and the rotation drive includes fixedly arranged on the limiter. The fixed rack 702 on the inner wall of the bit-through groove 701, the inside of the sliding block 66 is provided with a gear chamber 704, and the inside of the gear chamber 704 is provided with a rotating gear 703, and the rotating gear 703 is coaxially fixedly connected with the cross bar 7, The rotating gear 703 is engaged with the corresponding fixed rack 702 for transmission.

In the above technical solution, the self-rotation drive can make the cross bar 7 and the stirring plate 71 on it rotate, so as to stir the particles in the slurry in all directions, and during the rotation, no matter whether the particles are in the upper part or the lower part, they will It is moved outward by the stirring plate 71; at the same time, the stirring blades 6 set at different angles can also cause the slurry to flow in different directions in each area. This three-dimensional compound rheological environment can realize the flow rate of each microscopic area in the slurry. And the change of flow direction further enhances the mixing effect. Compared with the simple rotating or fixed structure, the introduction of this new structure can produce a more comprehensive and uniform effect, effectively eliminate the local "dead angle" area, and obtain a 360° mixing effect. It is the key to achieve high quality mixing.

Optionally, the cross bars 7 on both sides of the same sliding block 66 are coaxially arranged.

In the above technical solution, the crossbars 7 on both sides of the same sliding block 66 rotate synchronously to realize multiple outputs and movements of one drive, which can effectively reduce the size of the equipment and make full use of power resources.

The purpose of this application is also to provide a method for using a pharmaceutical and chemical mixer that uses vacuum stirring technology to prevent particle sedimentation, comprising the following steps:

The mixing drum 2 filled with particles is positioned and connected to the fixed seat 1, the machine head 3 is inserted into the top of the mixing drum 2, and the flexible connection between the machine head 3 and the mixing drum 2 is realized through the telescopic rod 4;

Start the first motor 52 to drive the rotation of the stirring shaft 5, thereby driving the cross bar 7 and the stirring blade 6 to carry out revolution stirring;

At the same time, start the second motor 6003 to drive the two worms 6002 to rotate synchronously. At this time, the two crankshafts 62 start to rotate, so that the swing rod 67 drives the stirring blade 6 to swing up and down, and the cross bar 7 moves up and down to stir;

At this time, while the sliding block 66 is moving up and down, the stirring plate 71 on the cross bar 7 is rotated and stirred under the meshing effect of the fixed rack 702 and the rotating gear 703 .

Compared with the prior art, the present application has at least the following technical effects or advantages:

This application realizes multi-directional, full-angle particle mixing by setting up swing components, rotation drive, and self-rotation drive, avoiding dead angles and particle sedimentation. Stirring force in one direction ensures that the particles are always in a state of motion with different trajectories. The swinging component and the rotating crossbar can perform revolution, so that the entire space on the inner wall of the mixing drum is stirred to avoid "dead angles". In addition, the stirring plate on the crossbar It can perform self-rotation action and cooperate with stirring blades at different angles to promote the mixing effect.

Description of drawings

Fig. 1 is the overall structure schematic diagram of the embodiment of the present application;

Fig. 2 is a schematic structural view of the outside of the stirring shaft in the embodiment of the present application;

Fig. 3 is a sectional view of the internal structure of the stirring shaft in the embodiment of the present application;

FIG. 4 is a disassembled view of the structure of the swing assembly in the embodiment of the present application;

Fig. 5 is an exploded view of a part of the structure of the swing assembly in the embodiment of the present application;

Figure 6 is an enlarged view of the structure at A in Figure 5;

Fig. 7 is a schematic structural diagram of the rotation drive in the embodiment of the present application;

In the picture:

1. Fixed seat; 2. Mixing drum; 3. Machine head; 4. Telescopic rod; 5. Stirring shaft; 6. Stirring blade; 7. Cross bar;

51. Rotary box; 52. The first motor;

61, mechanical slot; 62, crankshaft; 63, pull rod; 64, hinge seat; 65, pull rod; 66, sliding block; 67, swing rod; 68, adapting groove;

71. Stirring plate;

601, rotating block; 602, rotating groove;

701, limit through slot; 702, fixed rack; 703, rotating gear; 704, gear cavity;

6001, worm gear; 6002, worm; 6003, second motor.

Detailed ways

The embodiments of the present invention will be listed below in conjunction with the accompanying drawings, and the present invention will be further described in detail.

Referring to Figure 1 and Figure 2, the embodiment of the present application provides a pharmaceutical and chemical mixer that uses vacuum stirring technology to prevent particles from settling, including

Fixing seat 1;

Mixing drum 2, the mixing drum 2 is used to hold granular materials;

The machine head 3, the machine head 3 is set above the fixed seat 1 through the telescopic rod 4, and the machine head 3 and the top opening of the mixing drum 2 are movable to open and close;

Stirring shaft 5, stirring shaft 5 rotates and stirs through rotation drive;

Stirring blade 6, the stirring blade 6 is rotatably arranged on the side of the stirring shaft 5, and the angular swing is realized through the swing assembly;

Crossbar 7, crossbar 7 rotates by self-rotation drive.

In this embodiment, the oscillating assembly is oscillating while realizing the rotation of the stirring blade 6, thereby generating a multi-directional stirring force during the mixing process, so that the particles are always on different trajectories, preventing their sedimentation and poor mixing.

Referring to Fig. 3, the rotary drive includes a rotary box 51, the interior of the rotary box 51 is fixedly provided with a first motor 52, and the output shaft of the first motor 52 extends downward through the side wall of the rotary box 51 to the outside and is coaxially fixedly connected with the stirring shaft 5 .

In this embodiment, starting the first motor 52 drives the rotation of the stirring shaft 5, thereby allowing the cross bar 7 and the stirring blade 6 on it to revolve, and the swing assembly and the cross bar 7 can perform revolution while completing their own actions. In this way, the entire inner circumference of the mixing drum 2 can be stirred to avoid dead angles.

Referring to Fig. 4 and Fig. 5, a mechanical groove 61 is provided in the middle part of the stirring shaft 5, and the swing assembly includes a crankshaft 62 which is rotatably arranged inside the mechanical groove 61, and the lower end of the crankshaft 62 is provided with a pull rod 63 through shaft rotation, and the lower end of the pull rod 63 is fixedly arranged with a Hinge seat 64, between the inner wall of hinge seat 64 is provided with pull bar 65 through pin shaft rotation, and the lower end of pull bar 65 is fixedly provided with slide block 66; The two ends of slide block 66 respectively extend to the outside of stirring shaft 5 and are fixedly provided with swing bar 67, The swing rod 67 is arranged in a symmetrical structure up and down; one end of the swing rod 67 is provided with an adapting groove 68, and the adapting groove 68 is slidingly connected with the cylindrical rod of the stirring blade 6; 62 for rotation.

In this embodiment, when the crankshaft 62 rotates, it will drive the pull rod 63 to move up and down, and the pull rod 63 is connected to the pull rod 65 in rotation, so that the pull rod 65 can pull the sliding block 66 to move, so that the sliding block The swing rod 67 on the 66 drives the stirring blade 6 to swing up and down, and at the same time, the cross bar 7 can move up and down, so that the angle and motion trajectory of the cross bar 7 and each stirring blade 6 can be different, and various forces can be added. direction.

Referring to Fig. 4, the inner end of the circumferential rod of the stirring blade 6 is fixedly provided with a rotating block 601 arranged in an arc-shaped structure, and the outer wall of the stirring shaft 5 is provided with a rotating groove 602, which is rotationally connected with the rotating block 601.

In this embodiment, the stirring shaft 5 applies forces at different angles, which further improves the mixing effect.

Multiple stirring blades 6 are arranged at different initial angles in the horizontal direction.

In this embodiment, while the stirring blade 6 is swinging up and down, the stirring blade 6 will generate tangential motions in different directions.

Referring to Fig. 6, the synchronous drive includes a worm wheel 6001 fixedly arranged on the top side of the crankshaft 62. The worm wheel 6001 is meshed with a worm 6002, and the upper and lower worms 6002 are fixedly connected coaxially; the inner wall of the mechanical groove 61 is fixedly provided with a second motor 6003, and The output shaft of the second motor 6003 is fixedly connected with the worm screw 6002 coaxially.

In this embodiment, the second motor 6003 drives the worm 6002 to rotate, and the worm 6002 meshes with the worm wheel 6001, thereby driving the two worm wheels 6001 to rotate. At this time, the two crankshafts 62 rotate, so that the two groups of swing assemblies up and down Simultaneous work is performed while reducing the size of the device.

Referring to Fig. 7, the side of the stirring shaft 5 is penetrated with a limiting channel 701 corresponding to the sliding block 66, the limiting channel 701 communicates with the mechanical channel 61, and the rotation drive includes a motor fixedly arranged on the inner wall of the limiting channel 701. The fixed rack 702 is provided with a gear chamber 704 inside the sliding block 66, and a rotating gear 703 is arranged to rotate inside the gear chamber 704. The rotating gear 703 is coaxially fixedly connected with the cross bar 7, and the rotating gear 703 is meshed with the corresponding fixed rack 702 for transmission. .

The cross bars 7 on both sides of the same sliding block 66 are coaxially arranged.

In this embodiment, while the sliding block 66 is moving up and down, under the meshing effect of the fixed rack 702 and the rotating gear 703, the crossbar 7 rotates, so that the stirring plate 71 on the crossbar 7 rotates and stirs, and the rotation drives The horizontal bar 7 and the stirring plate 71 on it can be rotated to stir the particles in the slurry in all directions, and during the rotation, the particles, whether they are in the upper part or the lower part, will be brought to the outside by the stirring plate 71 At the same time, the stirring blades 6 set at different angles can also cause the slurry to flow in different directions in each area. This three-dimensional composite rheological environment can realize the change of flow velocity and flow direction in each microscopic area of the slurry, and further enhance the mixing. Effect, compared with a simple rotating or fixed structure, the introduction of this new structure can produce a more comprehensive and uniform effect, effectively eliminate local "dead angle" areas, and obtain a 360° mixing effect, which is the key to achieving high-quality mixing where.

Stirring plates 71 are fixedly arranged on the side of the cross bar 7, and a plurality of stirring plates 71 are arranged at equal intervals in a ring, and multiple sets of stirring plates 71 are arranged in the horizontal direction, and the effect and efficiency of stirring are increased by a plurality of stirring plates 71 .

The working principle of this embodiment: when the vacuum mixer for preventing particles from settling is needed, the particles are put into the mixing drum 2, and the mixing drum 2 is placed on the fixed seat 1. At this time, the first motor 52 is started by the controller Drive the rotation of the stirring shaft 5, so that the horizontal bar and the stirring blade 6 on it can revolve;

At this time, the second motor 6003 drives the worm 6002 to rotate, and the worm 6002 meshes with the worm wheel 6001, thereby driving the two worm wheels 6001 to rotate. At this time, the two crankshafts 62 rotate. During the rotation of the crankshaft 62, the crankshaft 62 drives the pull rod 63 to move up and down, and the pull rod 63 is connected to the pull rod 65 in rotation, so that the pull rod 65 can pull the sliding block 66 to move, so that the swing rod 67 can drive the stirring blade 6 to swing up and down, and at the same time Rod 7 can move up and down, so that the angle and trajectory of cross bar 7 and each stirring blade 6 can be different, and a variety of force application directions can be added. When sliding block 66 moves up and down, the inside of sliding block 66 The rotating gear 703 will move up and down on the outer wall of the fixed rack 702 provided in the limiting through groove 701, and the fixed rack 702 meshes with the rotating gear 703, thereby driving the coaxial cross bar 7 to rotate, so that the cross bar Stirring plate 71 on 7 rotates and stirs.

Claims (10)

1. A pharmaceutical and chemical mixer using vacuum mixing technology to prevent particle settlement, comprising a fixed seat, a mixing drum, a machine head, a stirring shaft, stirring blades and a cross bar, characterized in that the mixing drum is used to hold granular materials The machine head is movably arranged on the upper side of the fixed seat through the telescopic rod; the stirring shaft is driven to rotate and stir; the stirring blade is rotatably arranged on the side of the stirring shaft, and the stirring blade realizes angular swing through the swing assembly; Said crossbar rotates by rotation drive. 2. A pharmaceutical and chemical mixer that uses vacuum stirring technology to prevent particle settlement according to claim 1, wherein the rotating drive includes a rotating box, and a first motor is fixed inside the rotating box, and the first motor is fixed inside the rotating box. A motor output shaft extends downward through the side wall of the rotating box to the outside and is coaxially fixedly connected with the stirring shaft. 3. A pharmaceutical and chemical mixer that uses vacuum stirring technology to prevent particle settlement according to claim 1, wherein a mechanical groove is provided in the middle of the stirring shaft, and the swing assembly includes a crankshaft that is rotatably arranged inside the mechanical groove , the lower end of the crankshaft is provided with a pull rod through shaft rotation, the lower end of the pull rod is fixedly provided with a hinge seat, the inner wall of the hinge seat is provided with a pull rod through the rotation of a pin shaft, and the lower end of the pull rod is fixedly provided with a sliding block; The two ends of the sliding block respectively extend to the outside of the stirring shaft and are fixedly equipped with a swing rod, which is arranged in a symmetrical structure up and down; one end of the swing rod is provided with an adapting groove, and the adapting groove slides with the cylindrical rod of the stirring blade connection; the swing assembly is provided with two sets of upper and lower structures, and the two crankshafts are driven to rotate by synchronous driving. 4. A kind of medicine and chemical industry mixer that adopts vacuum mixing technology to prevent particle settlement according to claim 1, it is characterized in that, the inner end of the circumferential rod of the stirring blade is fixedly provided with a rotating block that is arranged in an arc-shaped structure, and the The outer wall of the stirring shaft is provided with a rotating groove, and the rotating groove is rotatably connected with the rotating block. 5. A pharmaceutical and chemical mixer using vacuum stirring technology to prevent particle settlement according to claim 1, wherein a plurality of stirring blades are arranged at different initial angles in the horizontal direction. 6. A pharmaceutical and chemical mixer that uses vacuum stirring technology to prevent particle settlement according to claim 3, wherein the synchronous drive includes a worm wheel fixed on the top side of the crankshaft, and the worm wheel is meshed with a worm, The two upper and lower worms are fixedly connected coaxially; the inner wall of the mechanical groove is fixedly provided with a second motor, and the output shaft of the second motor is fixedly connected coaxially with the worm. 7. A pharmaceutical and chemical mixer using vacuum stirring technology to prevent particle settlement according to claim 1, characterized in that a stirring plate is fixedly arranged on the side of the cross bar, and the stirring plate is provided with a plurality of circular and equidistant , and multiple sets of stirring plates are arranged in the horizontal direction. 8. A pharmaceutical and chemical mixer using vacuum stirring technology to prevent particle settlement according to claim 6, characterized in that, the side of the stirring shaft is penetrated with a limit channel corresponding to the sliding block, and the limit The bit through groove is connected with the mechanical groove, and the self-rotation drive includes a fixed rack fixedly arranged on the inner wall of the limit through groove, and a gear cavity is opened inside the sliding block, and a rotating gear is arranged inside the gear cavity. The rotating gear is coaxially fixedly connected with the cross bar, and the rotating gear is engaged with the corresponding fixed rack for transmission. 9. A pharmaceutical and chemical mixer using vacuum stirring technology to prevent particle settlement according to claim 1, characterized in that the horizontal bars on both sides of the same sliding block are coaxially arranged. 10. A method for using a pharmaceutical and chemical mixer using vacuum mixing technology to prevent particle settlement, comprising the following steps: Position and connect the mixing drum containing particles to the fixed seat, insert the machine head into the top of the mixing drum, and realize the movable connection between the machine head and the mixing drum through the telescopic rod; Start the first motor to drive the rotation of the stirring shaft, thereby driving the cross bar and the stirring blade to perform revolution stirring; At the same time, start the second motor to drive the two worms to rotate synchronously. At this time, the two crankshafts start to rotate, so that the swing rod drives the stirring blade to swing up and down, and the cross bar moves up and down to stir; At this time, while the sliding block moves up and down, the stirring plate on the cross bar is rotated and stirred under the meshing action of the fixed rack and the rotating gear.