CN116492958A - Efficient type device and process for preparing ivermectin special for antiparasitic - Google Patents

Efficient type device and process for preparing ivermectin special for antiparasitic Download PDF

Info

Publication number
CN116492958A
CN116492958A CN202310436310.7A CN202310436310A CN116492958A CN 116492958 A CN116492958 A CN 116492958A CN 202310436310 A CN202310436310 A CN 202310436310A CN 116492958 A CN116492958 A CN 116492958A
Authority
CN
China
Prior art keywords
ivermectin
limit
component
storage
crude
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202310436310.7A
Other languages
Chinese (zh)
Other versions
CN116492958B (en
Inventor
仇明生
吴小凯
李云海
张艳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Oak Animal Medicine Co ltd
Original Assignee
Jiangsu Oak Animal Medicine Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Oak Animal Medicine Co ltd filed Critical Jiangsu Oak Animal Medicine Co ltd
Priority to CN202310436310.7A priority Critical patent/CN116492958B/en
Publication of CN116492958A publication Critical patent/CN116492958A/en
Application granted granted Critical
Publication of CN116492958B publication Critical patent/CN116492958B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18Stationary reactors having moving elements inside
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D9/00Crystallisation
    • B01D9/0018Evaporation of components of the mixture to be separated
    • B01D9/0031Evaporation of components of the mixture to be separated by heating
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D9/00Crystallisation
    • B01D9/02Crystallisation from solutions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Organic Chemistry (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

本发明公开了一种高效型抗寄生虫专用伊维菌素制备装置及制备工艺,应用在伊维菌素制备技术领域,本发明通过设置制备机构,储存组件可以对伊维菌素粗品溶液进行暂时性储存,送料组件在外接伊维菌素粗品溶液输送设备后,将伊维菌素粗品溶液输送到储存组件内,搅拌组件可以对伊维菌素粗品溶液进行搅拌混合,便于伊维菌素粗品溶液在后续的结晶化加工处理,通过设置结晶机构,限位组件可以对更换组件进行支撑和限位,并且可以对伊维菌素粗品溶液进行暂时性储存,更换组件可以带动反应组件进行移动,便于将反应组件从限位组件内取出和存入,反应组件可以将晶种进行更换,并对晶种进行暂时性储存。

The invention discloses a high-efficiency anti-parasitic special ivermectin preparation device and a preparation process, which are applied in the technical field of ivermectin preparation. In the present invention, by setting a preparation mechanism, the storage component can carry out the crude ivermectin solution Temporary storage, after the feeding component is connected to the ivermectin crude solution delivery equipment, the ivermectin crude solution is transported to the storage component, and the stirring component can stir and mix the ivermectin crude solution, which is convenient for ivermectin In the subsequent crystallization processing of the crude product solution, by setting the crystallization mechanism, the limit component can support and limit the replacement component, and can temporarily store the ivermectin crude product solution, and the replacement component can drive the reaction component to move , it is convenient to take out and store the reaction component from the limit component, and the reaction component can replace the seed crystal and temporarily store the seed crystal.

Description

一种高效型抗寄生虫专用伊维菌素制备装置及制备工艺A high-efficiency anti-parasitic special ivermectin preparation device and preparation process

技术领域technical field

本发明属于伊维菌素制备技术领域,特别涉及一种高效型抗寄生虫专用伊维菌素制备装置及制备工艺。The invention belongs to the technical field of ivermectin preparation, and in particular relates to a high-efficiency anti-parasitic special ivermectin preparation device and a preparation process.

背景技术Background technique

高效性抗寄生虫专用伊维菌素,是新型的广谱、高效、低毒抗生素类抗寄生虫药,对体内外寄生虫特别是线虫和节肢动物均有良好驱杀作用,常用于对兽类的治疗,在对伊维菌素进行制备时,会在反应釜中,将甲苯与阿维菌素加入至釜中,在保护气保护下加入催化剂,用氢气置换出保护气后,调整加热温度为65~75℃,压强为0.5~0.7MPa,阿维菌素与氢气发生加氢反应,得到伊维菌素粗品,将伊维菌素粗品用溶剂溶解,加热搅拌至完全溶解并保温,得到粗品溶液,向粗品溶液中加入纯化水和甲酰胺并控制流加流速,降温,得稀释液,向稀释液中加入晶种后养晶,运用控温方法,将稀释液降温至一定温度,最后经过抽滤、洗涤、干燥可得到高纯度的伊维菌素精粉High-efficiency anti-parasitic special ivermectin is a new type of broad-spectrum, high-efficiency, and low-toxicity antibiotic anti-parasitic drug. It has a good killing effect on internal and external parasites, especially nematodes and arthropods. When preparing ivermectin, toluene and avermectin will be added to the kettle in the reaction kettle, and the catalyst will be added under the protection of protective gas. After the protective gas is replaced with hydrogen, the heating will be adjusted. The temperature is 65-75°C, the pressure is 0.5-0.7MPa, hydrogenation reaction occurs between avermectin and hydrogen to obtain crude ivermectin, dissolve the crude ivermectin in a solvent, heat and stir until completely dissolved and keep warm. To obtain the crude product solution, add purified water and formamide to the crude product solution and control the feeding flow rate, lower the temperature to obtain a diluted solution, add crystal seeds to the diluted solution and grow crystals, use the temperature control method to cool the diluted solution to a certain temperature, Finally, after suction filtration, washing and drying, high-purity ivermectin powder can be obtained

现有的高效型抗寄生虫专用伊维菌素制备装置及制备工艺在制备的时候有以下缺点:The existing high-efficiency anti-parasitic special-purpose ivermectin preparation device and preparation process have the following disadvantages during preparation:

1、无法根据所需要求实时定量输送伊维菌素粗品溶液,不便于对伊维菌素粗品的添加和加工;1. It is impossible to quantitatively transport the crude ivermectin solution in real time according to the required requirements, and it is inconvenient to add and process the crude ivermectin;

2、缺少对大量晶种更换的结构,不便于对伊维菌素粗品溶液的结晶加工。2. Lack of a structure for replacing a large number of crystal seeds, which is inconvenient for crystallization processing of crude ivermectin solution.

发明内容Contents of the invention

本发明的目的在于针对现有的一种高效型抗寄生虫专用伊维菌素制备装置及制备工艺,其优点是:The purpose of the present invention is to aim at the existing high-efficiency anti-parasitic special-purpose ivermectin preparation device and preparation process, and its advantage is:

1、无法根据所需要求实时定量输送伊维菌素粗品溶液,不便于对伊维菌素粗品的添加和加工;1. It is impossible to quantitatively transport the crude ivermectin solution in real time according to the required requirements, and it is inconvenient to add and process the crude ivermectin;

2、缺少对大量晶种更换的结构,不便于对伊维菌素粗品溶液的结晶加工。2. Lack of a structure for replacing a large number of crystal seeds, which is inconvenient for crystallization processing of crude ivermectin solution.

本发明的上述技术目的是通过以下技术方案得以实现的:一种高效型抗寄生虫专用伊维菌素制备装置及制备工艺,包括制备机构和结晶机构,所述制备机构包括储存组件、送料组件和搅拌组件,所述送料组件连通在储存组件顶部的后侧,所述搅拌组件栓接在储存组件的顶部,所述结晶机构包括限位组件、更换组件、反应组件和加热组件,所述限位组件栓接在储存组件的底部,所述更换组件卡接在限位组件的内壁,所述反应组件卡接在更换组件的内壁,所述加热组件栓剂诶在反应组件的内壁。The above technical purpose of the present invention is achieved through the following technical solutions: a high-efficiency anti-parasitic special ivermectin preparation device and preparation process, including a preparation mechanism and a crystallization mechanism, and the preparation mechanism includes a storage component and a feeding component and a stirring assembly, the feeding assembly is connected to the rear side of the top of the storage assembly, the stirring assembly is bolted to the top of the storage assembly, the crystallization mechanism includes a limiting assembly, a replacement assembly, a reaction assembly and a heating assembly, the limiting assembly The position component is bolted to the bottom of the storage component, the replacement component is clamped to the inner wall of the limit component, the reaction component is clamped to the inner wall of the replacement component, and the heating component suppository is clamped to the inner wall of the reaction component.

采用上述技术方案,通过设置制备机构和结晶机构,制备机构可以在外接伊维菌素粗品溶液输送设备后,对伊维菌素粗品溶液进行细致化搅拌加工,并且将完成制备后伊维菌素产生的废气进行排放,结晶机构可以便于更换晶种,并且对伊维菌素粗品溶液进行结晶化加工处理。Adopting the above-mentioned technical scheme, by setting up the preparation mechanism and the crystallization mechanism, the preparation mechanism can fine-tune and process the ivermectin crude product solution after being externally connected with the ivermectin crude product solution delivery equipment, and will complete the prepared ivermectin The generated exhaust gas is discharged, and the crystallization mechanism can facilitate the replacement of crystal seeds, and carry out crystallization processing on the crude ivermectin solution.

本发明进一步设置为:所述储存组件包括储存罐、支撑环和抽风扇,所述支撑环栓接在储存罐的顶部,所述抽风扇栓接在储存罐顶部的前侧。The present invention further provides that: the storage assembly includes a storage tank, a support ring and an exhaust fan, the support ring is bolted to the top of the storage tank, and the exhaust fan is bolted to the front side of the top of the storage tank.

采用上述技术方案,通过设置储存组件,储存罐可以对伊维菌素粗品溶液进行暂时性储存,便于搅拌组件对伊维菌素粗品溶液进行搅拌,支撑环可以对送料组件进行支撑和限位,抽风扇可以在通电并启动后,将储存罐内因伊维菌素粗品溶液产生的废气进行排放。With the above technical scheme, by setting up the storage component, the storage tank can temporarily store the crude ivermectin solution, which is convenient for the stirring component to stir the crude ivermectin solution, and the support ring can support and limit the feeding component. After the exhaust fan is energized and started, the waste gas generated by the crude ivermectin solution in the storage tank can be discharged.

本发明进一步设置为:所述送料组件包括入料泵、储料管和阀门,所述阀门连通在储存罐顶部的后侧,所述储料管连通在阀门的顶部,所述入料泵连通在储料管的顶部。The present invention is further set as follows: the feeding assembly includes a feeding pump, a material storage pipe and a valve, the valve is connected to the rear side of the top of the storage tank, the material storage pipe is connected to the top of the valve, and the feeding pump is connected to on top of the stock tube.

采用上述技术方案,通过设置送料组件,入料泵可以外接在伊维菌素粗品溶液输送设备上,而且可以在通电并启动后,将伊维菌素粗品溶液抽送到出料管内,储料管为带有玻璃观察窗结构的储存管,可以对伊维菌素粗品溶液进行定量储存,以便于实时添加伊维菌素粗品溶液,阀门可以对储料管进行启闭操作,可以便于储料管将伊维菌素粗品溶液输送至储存罐内。With the above technical scheme, by setting the feeding component, the feeding pump can be externally connected to the ivermectin crude product solution delivery equipment, and after the power is turned on and started, the ivermectin crude product solution can be pumped into the discharge pipe, and the storage pipe It is a storage tube with a glass observation window structure, which can quantitatively store the crude ivermectin solution, so that the crude ivermectin solution can be added in real time. The valve can open and close the storage tube, which can facilitate the storage tube The crude ivermectin solution is delivered to the storage tank.

本发明进一步设置为:所述搅拌组件包括伺服电机、转动杆和搅拌管,所述伺服电机栓接在储存罐的顶部,所述转动杆栓接在伺服电机底部的输出端,所述转动杆贯穿储存罐的顶部与储存罐的顶部转动连接,所述搅拌管连通在转动杆的表面。The present invention is further provided that: the stirring assembly includes a servo motor, a rotating rod and a stirring tube, the servo motor is bolted to the top of the storage tank, the rotating rod is bolted to the output end at the bottom of the servo motor, and the rotating rod The top of the penetrating storage tank is rotatably connected with the top of the storage tank, and the stirring tube communicates with the surface of the rotating rod.

采用上述技术方案,通过设置搅拌组件,伺服电机可以在通电并启动后,将电能转化为旋转的机械能,再将旋转的机械能传递给转动杆,可以带动搅拌管随着伺服电机进行旋转,搅拌管为两端为两个九十度的弯头,弯头的入口设在同一方向的水管,在搅拌管旋转时,搅拌管一端的弯头的入口会与溶液接触并移动,将溶液输送到搅拌管内,再传输到另一端弯头处,另一端弯头的入口则会背对溶液进行移动,从而不会影响溶液从另一端弯头的入口处送出,经过搅拌管内部的溶液则会受到搅拌管的挤压而增加溶液混合的效率。With the above-mentioned technical solution, by setting up the stirring component, the servo motor can convert the electric energy into the mechanical energy of rotation after it is energized and started, and then transmit the mechanical energy of rotation to the rotating rod, which can drive the stirring tube to rotate with the servo motor, and the stirring tube It is two 90-degree elbows at both ends, and the inlets of the elbows are set in the same direction of the water pipe. When the stirring tube rotates, the inlet of the elbow at one end of the stirring tube will contact and move with the solution, and the solution will be transported to the stirring tube. In the tube, and then transferred to the other end of the elbow, the entrance of the other end of the elbow will move away from the solution, so as not to affect the solution sent from the entrance of the other end of the elbow, and the solution passing through the inside of the stirring tube will be stirred The extrusion of the tube increases the efficiency of solution mixing.

本发明进一步设置为:所述限位组件包括限位盒、限位滑板和存取槽,所述限位盒栓接在储存罐的底部,所述限位滑板栓接在限位盒内壁的前侧和内壁的后侧,所述存取槽开设在限位盒的右侧。The present invention is further configured as follows: the limit assembly includes a limit box, a limit slide plate and an access slot, the limit box is bolted to the bottom of the storage tank, and the limit slide plate is bolted to the inner wall of the limit box On the front side and the rear side of the inner wall, the access slot is opened on the right side of the limit box.

采用上述技术方案,通过设置限位组件,限位盒可以对更换组件进行支撑和限位,限位滑板可以增加更换组件在滑动时的稳定性,存取槽可以对更换组件进行暂时性储存,以便于更换组件对晶种的更换。With the above technical solution, by setting the limit component, the limit box can support and limit the replacement component, the limit slide plate can increase the stability of the replacement component when sliding, and the access slot can temporarily store the replacement component. In order to facilitate the replacement of the seed crystal by the replacement component.

本发明进一步设置为:所述更换组件包括限位框架、限位卡槽和封闭板,所述限位框架设在限位盒的内侧,所述限位框架的前侧和后侧与限位滑板的表面滑动连接,所述限位卡槽开设在限位框架的内壁,所述封闭板栓接在限位框架的右侧,所述限位框架的表面与存取槽接触。The present invention is further configured as follows: the replacement assembly includes a limit frame, a limit card slot and a closing plate, the limit frame is arranged inside the limit box, the front side and the rear side of the limit frame are in contact with the limit The surface of the slide plate is slidably connected, the limit card slot is opened on the inner wall of the limit frame, the closing plate is bolted to the right side of the limit frame, and the surface of the limit frame is in contact with the access groove.

采用上述技术方案,通过设置更换组件,限位框架可以带动反应组件进行移动,限位卡槽可以对反应组件进行支撑和限位,便于更换反应组件,封闭板可以与存取槽接触,增加限位盒内的密封性。With the above technical scheme, by setting the replacement components, the limit frame can drive the reaction component to move, the limit card slot can support and limit the reaction component, which is convenient for replacing the reaction component, and the closing plate can be in contact with the access slot, increasing the limit. Sealing inside the bit box.

本发明进一步设置为:所述反应组件包括限位圈板、存放盒和安装槽,所述存放盒卡接在限位卡槽的内壁,所述安装槽开设在存放盒内壁的底部,所述限位圈板栓剂诶在存放盒表面的顶部,所述限位圈板的表面与限位卡槽的内壁接触。The present invention is further configured as follows: the reaction assembly includes a limit ring plate, a storage box and an installation groove, the storage box is clamped on the inner wall of the limit card groove, the installation groove is opened at the bottom of the inner wall of the storage box, the The suppository of the limit circle plate is on the top of the surface of the storage box, and the surface of the limit circle plate is in contact with the inner wall of the limit card slot.

采用上述技术方案,通过设置反应组件,限位圈板可以增加存放盒放置在限位卡槽内时的稳定性,存放盒可以对晶种进行暂时性储存,以便于对伊维菌素粗品溶液进行结晶化加工处理,安装槽可以对加热组件进行支撑和限位,便于加热组件对晶种进行辅助性加热,提高结晶加工的效率。Using the above technical scheme, by setting the reaction component, the limit ring plate can increase the stability of the storage box when it is placed in the limit card slot, and the storage box can temporarily store the seed crystal, so as to facilitate the analysis of the crude ivermectin solution. For crystallization processing, the installation groove can support and limit the heating component, which is convenient for the heating component to assist in heating the seed crystal and improve the efficiency of crystallization processing.

本发明进一步设置为:所述加热组件包括导热板、导热圈和加热器,所述导热板卡接在安装槽的内壁,所述导热圈焊接在导热板内壁的两侧,所述加热器栓接在导热板的底部,所述加热器的底部贯穿存放盒的底部与存放盒栓接。The present invention is further configured as follows: the heating assembly includes a heat conduction plate, a heat conduction ring and a heater, the heat conduction plate is clamped on the inner wall of the installation groove, the heat conduction ring is welded on both sides of the heat conduction plate inner wall, and the heater plug Connected to the bottom of the heat conducting plate, the bottom of the heater passes through the bottom of the storage box and is bolted to the storage box.

采用上述技术方案,通过设置加热组件,加热器可以在通电并启动后,将电能转化为热能,再将热能传递给导热板,导热板可以将热能传递给导热圈,导热板和导热圈可以将热量传递给伊维菌素粗品溶液,从而增加伊维菌素粗品溶液与晶种结晶化加工处理的效率。With the above technical solution, by setting the heating component, the heater can convert the electric energy into heat energy after being powered on and started, and then transfer the heat energy to the heat conducting plate, and the heat conducting plate can transfer the heat energy to the heat conducting ring, and the heat conducting plate and the heat conducting ring can The heat is transferred to the crude ivermectin solution, thereby increasing the crystallization processing efficiency of the crude ivermectin solution and seed crystals.

本发明进一步设置为:所所述搅拌管共设有五个,所述搅拌管由不锈钢材料制成。The present invention is further configured as follows: there are five stirring tubes in total, and the stirring tubes are made of stainless steel.

采用上述技术方案,通过设有五个搅拌管,五个搅拌管可以极大地提高对伊维菌素粗品溶液搅拌的效率,并且不锈钢材料的搅拌管具有较高的硬度和韧性,同时还具有较高的耐锈蚀性,提高了搅拌管的使用寿命。With the above technical scheme, five stirring tubes can greatly improve the efficiency of stirring the crude ivermectin solution, and the stirring tubes made of stainless steel have high hardness and toughness, and also have relatively high hardness. High corrosion resistance improves the service life of the mixing tube.

一种高效型抗寄生虫专用伊维菌素的制备工艺,包括以下步骤:A preparation process of high-efficiency anti-parasitic special ivermectin, comprising the following steps:

S1.入料搅拌:首先,将入料泵外接在伊维菌素粗品溶液输送设备的输出端,之后将制备机构通电后启动,在伊维菌素粗品溶液进入到储存罐内时,伺服电机会将电能转化为旋转的机械能,再将旋转的机械能传递给转动杆,转动杆就会随着伺服电机进行转动,并且带动搅拌管进行转动,伊维菌素粗品溶液会随着搅拌管的搅动而产生移动,并形成漩涡,同时伊维菌素粗品溶液会在移动时穿过搅拌管,在完成对伊维菌素粗品溶液搅拌加工后,可以让结晶机构对伊维菌素粗品溶液进行结晶加工,在完成对伊维菌素粗品溶液结晶加工后,抽风扇可以将储存罐内反应后多余的气体排出,直至完成对伊维菌素的制备;S1. Feeding and stirring: First, connect the feeding pump to the output end of the ivermectin crude product solution delivery equipment, and then start the preparation mechanism after the power is turned on. When the ivermectin crude product solution enters the storage tank, the servo motor It converts electrical energy into mechanical energy of rotation, and then transmits the mechanical energy of rotation to the rotating rod. The rotating rod will rotate with the servo motor and drive the stirring tube to rotate. The crude ivermectin solution will be stirred with the stirring tube It moves and forms a vortex. At the same time, the crude ivermectin solution will pass through the stirring tube when moving. After the stirring process of the crude ivermectin solution is completed, the crystallization mechanism can be used to crystallize the crude ivermectin solution. Processing, after completing the crystallization processing of the crude ivermectin solution, the exhaust fan can discharge the excess gas after the reaction in the storage tank until the preparation of ivermectin is completed;

S2.升温结晶:首先,将存放盒内放入晶种,再将存放盒置入限位卡槽内,将限位框架沿着限位滑板置入限位盒内,直至封闭板与存取槽接触并闭合,再将完成搅拌加工的伊维菌素粗品溶液,输送至存放盒内,之后将结晶机构通电并启动,加热器会在通电后将电能转化为热能,再将热能传递给导热板,导热板会将热量传递给导热圈,导热板和导热圈就会将热量传递给伊维菌素粗品溶液,伊维菌素粗品溶液就会与晶种因为热量而逐渐产生结晶反应,直至伊维菌素粗品溶液与晶种完全完成结晶反应后,即可将限位框架从存取槽内取出,将完成完成制备的伊维菌素取出即可。S2. Heating crystallization: First, put the seed crystal into the storage box, then put the storage box into the limit card slot, put the limit frame into the limit box along the limit slide plate, until the closing plate and the access The tanks are contacted and closed, and then the crude ivermectin solution that has been stirred and processed is transported to the storage box, and then the crystallization mechanism is powered on and started. The heater will convert the electric energy into heat energy after power on, and then transfer the heat energy to the heat conduction plate, the heat conduction plate will transfer heat to the heat conduction ring, and the heat conduction plate and heat conduction ring will transfer heat to the crude ivermectin solution, and the crude ivermectin solution will gradually produce crystallization reaction with the seed crystal due to the heat, until After the crude ivermectin solution and the seed crystal completely complete the crystallization reaction, the limiting frame can be taken out from the access tank, and the prepared ivermectin can be taken out.

综上所述,本发明具有以下有益效果:In summary, the present invention has the following beneficial effects:

1、通过设置制备机构,储存组件可以对伊维菌素粗品溶液进行暂时性储存,送料组件在外接伊维菌素粗品溶液输送设备后,将伊维菌素粗品溶液输送到储存组件内,搅拌组件可以对伊维菌素粗品溶液进行搅拌混合,便于伊维菌素粗品溶液在后续的结晶化加工处理;1. By setting up the preparation mechanism, the storage component can temporarily store the crude ivermectin solution. After the feeding component is connected to the crude ivermectin solution delivery equipment, the crude ivermectin solution is transported to the storage component and stirred The component can stir and mix the crude ivermectin solution, which is convenient for the subsequent crystallization processing of the crude ivermectin solution;

2、通过设置结晶机构,限位组件可以对更换组件进行支撑和限位,并且可以对伊维菌素粗品溶液进行暂时性储存,更换组件可以带动反应组件进行移动,便于将反应组件从限位组件内取出和存入,反应组件可以将晶种进行更换,并对晶种进行暂时性储存,便于晶种与伊维菌素粗品溶液进行结晶化加工处理,加热组件可以对反应组件内的晶种和伊维菌素粗品溶液进行加热,从而增加伊维菌素与晶种结晶化加工处理的效率。2. By setting the crystallization mechanism, the limit component can support and limit the replacement component, and can temporarily store the crude ivermectin solution. The replacement component can drive the reaction component to move, so that the reaction component can be moved from the limit The reaction component can replace the seed crystal and temporarily store the seed crystal, which is convenient for crystallization processing of the seed crystal and the crude ivermectin solution. The heating component can clean the crystal in the reaction component. Seed and crude ivermectin solution are heated, thereby increasing the efficiency of crystallization processing of ivermectin and seed crystals.

附图说明Description of drawings

图1是本发明的整体结构示意图;Fig. 1 is the overall structural representation of the present invention;

图2是本发明的制备机构结构示意图;Fig. 2 is a schematic structural view of the preparation mechanism of the present invention;

图3是本发明的储存组件结构示意图;Fig. 3 is a schematic structural view of the storage assembly of the present invention;

图4是本发明的送料组结构示意图;Fig. 4 is the structural representation of feeding group of the present invention;

图5是本发明的搅拌组件结构示意图;Fig. 5 is a schematic structural view of the stirring assembly of the present invention;

图6是本发明的结晶机构结构示意图;Fig. 6 is a schematic structural view of the crystallization mechanism of the present invention;

图7是本发明的限位组件结构示意图;Fig. 7 is a schematic structural diagram of the limiting assembly of the present invention;

图8是本发明的更换组件结构示意图;Fig. 8 is a structural schematic diagram of the replacement assembly of the present invention;

图9是本发明的反应组件结构示意图;Fig. 9 is a structural schematic diagram of the reaction assembly of the present invention;

图10是本发明的加热组件结构示意图。Fig. 10 is a schematic structural view of the heating assembly of the present invention.

附图标记:1、制备机构;101、储存组件;1011、储存罐;1012、支撑环;1013、抽风扇;102、送料组件;1021、入料泵;1022、储料管;1023、阀门;103、搅拌组件;1031、伺服电机;1032、转动杆;1033、搅拌管;2、结晶机构;201、限位组件;2011、限位盒;2012、限位滑板;2013、存取槽;202、更换组件;2021、限位框架;2022、限位卡槽;2023、封闭板;203、反应组件;2031、限位圈板;2032、存放盒;2033、安装槽;204、加热组件;2041、导热板;2042、导热圈;2043、加热器。Reference signs: 1. preparation mechanism; 101. storage component; 1011. storage tank; 1012. support ring; 1013. exhaust fan; 102. feeding component; 1021. feeding pump; 1022. storage pipe; 103. Stirring component; 1031. Servo motor; 1032. Rotating rod; 1033. Stirring tube; 2. Crystallization mechanism; 201. Limit component; 2011. Limit box; 2012. Limit slide plate; 2013. Access slot; 202 2021, limit frame; 2022, limit card slot; 2023, closed plate; 203, reaction component; 2031, limit ring plate; 2032, storage box; 2033, installation slot; 204, heating component; 2041 , heat conducting plate; 2042, heat conducting ring; 2043, heater.

具体实施方式Detailed ways

以下结合附图对本发明作进一步详细说明。The present invention will be described in further detail below in conjunction with the accompanying drawings.

实施例1:Example 1:

参考图1-5,一种高效型抗寄生虫专用伊维菌素制备装置,包括制备机构1,制备机构1包括储存组件101、送料组件102和搅拌组件103,送料组件102连通在储存组件101顶部的后侧,搅拌组件103栓接在储存组件101的顶部,通过设置制备机构1,储存组件101可以对伊维菌素粗品溶液进行暂时性储存,送料组件102在外接伊维菌素粗品溶液输送设备后,将伊维菌素粗品溶液输送到储存组件101内,搅拌组件103可以对伊维菌素粗品溶液进行搅拌混合,便于伊维菌素粗品溶液在后续的结晶化加工处理。Referring to Figures 1-5, a high-efficiency anti-parasitic special ivermectin preparation device includes a preparation mechanism 1. The preparation mechanism 1 includes a storage component 101, a feeding component 102 and a stirring component 103. The feeding component 102 is connected to the storage component 101. On the rear side of the top, the stirring assembly 103 is bolted to the top of the storage assembly 101. By setting the preparation mechanism 1, the storage assembly 101 can temporarily store the ivermectin crude product solution, and the feeding assembly 102 is externally connected to the ivermectin crude product solution. After conveying the equipment, the crude ivermectin solution is transported into the storage component 101, and the stirring component 103 can stir and mix the crude ivermectin solution, so as to facilitate the subsequent crystallization processing of the crude ivermectin solution.

如图3所示,储存组件101包括储存罐1011、支撑环1012和抽风扇1013,支撑环1012栓接在储存罐1011的顶部,抽风扇1013栓接在储存罐1011顶部的前侧,通过设置储存组件101,储存罐1011可以对伊维菌素粗品溶液进行暂时性储存,便于搅拌组件103对伊维菌素粗品溶液进行搅拌,支撑环1012可以对送料组件102进行支撑和限位,抽风扇1013可以在通电并启动后,将储存罐1011内因伊维菌素粗品溶液产生的废气进行排放。As shown in Figure 3, the storage assembly 101 includes a storage tank 1011, a support ring 1012 and an exhaust fan 1013, the support ring 1012 is bolted to the top of the storage tank 1011, and the exhaust fan 1013 is bolted to the front side of the storage tank 1011 top, by setting The storage component 101, the storage tank 1011 can temporarily store the crude ivermectin solution, which is convenient for the stirring component 103 to stir the crude ivermectin solution, the support ring 1012 can support and limit the feeding component 102, and the exhaust fan 1013 can discharge the waste gas produced by the crude ivermectin solution in the storage tank 1011 after being powered on and started.

如图4所示,送料组件102包括入料泵1021、储料管1022和阀门1023,阀门1023连通在储存罐1011顶部的后侧,储料管1022连通在阀门1023的顶部,入料泵1021连通在储料管1022的顶部,通过设置送料组件102,入料泵1021可以外接在伊维菌素粗品溶液输送设备上,而且可以在通电并启动后,将伊维菌素粗品溶液抽送到出料管内,储料管1022为带有玻璃观察窗结构的储存管,可以对伊维菌素粗品溶液进行定量储存,以便于实时添加伊维菌素粗品溶液,阀门1023可以对储料管1022进行启闭操作,可以便于储料管1022将伊维菌素粗品溶液输送至储存罐1011内。As shown in Figure 4, the feeding assembly 102 includes a feeding pump 1021, a material storage pipe 1022 and a valve 1023, the valve 1023 is connected to the rear side of the top of the storage tank 1011, the material storage pipe 1022 is connected to the top of the valve 1023, and the feeding pump 1021 Connected to the top of the storage pipe 1022, by setting the feeding assembly 102, the feeding pump 1021 can be externally connected to the ivermectin crude product solution delivery equipment, and can pump the ivermectin crude product solution to the outlet after the power is turned on and started. In the feed pipe, the storage pipe 1022 is a storage pipe with a glass observation window structure, which can quantitatively store the crude ivermectin solution, so as to add the crude ivermectin solution in real time, and the valve 1023 can control the storage pipe 1022. The opening and closing operation can facilitate the delivery of the crude ivermectin solution to the storage tank 1011 by the storage pipe 1022 .

如图5所示,搅拌组件103包括伺服电机1031、转动杆1032和搅拌管1033,伺服电机1031栓接在储存罐1011的顶部,转动杆1032栓接在伺服电机1031底部的输出端,转动杆1032贯穿储存罐1011的顶部与储存罐1011的顶部转动连接,搅拌管1033连通在转动杆1032的表面,通过设置搅拌组件103,伺服电机1031可以在通电并启动后,将电能转化为旋转的机械能,再将旋转的机械能传递给转动杆1032,可以带动搅拌管1033随着伺服电机1031进行旋转,搅拌管1033为两端为两个九十度的弯头,弯头的入口设在同一方向的水管,在搅拌管1033旋转时,搅拌管1033一端的弯头的入口会与溶液接触并移动,将溶液输送到搅拌管1033内,再传输到另一端弯头处,另一端弯头的入口则会背对溶液进行移动,从而不会影响溶液从另一端弯头的入口处送出,经过搅拌管1033内部的溶液则会受到搅拌管1033的挤压而增加溶液混合的效率。As shown in Figure 5, stirring assembly 103 comprises servo motor 1031, rotating rod 1032 and stirring tube 1033, and servo motor 1031 is bolted on the top of storage tank 1011, and rotating rod 1032 is bolted on the output end of servo motor 1031 bottom, and rotating rod 1032 runs through the top of the storage tank 1011 and is rotationally connected to the top of the storage tank 1011. The stirring tube 1033 is connected to the surface of the rotating rod 1032. By setting the stirring assembly 103, the servo motor 1031 can convert electrical energy into rotational mechanical energy after being energized and started. , and then transmit the rotating mechanical energy to the rotating rod 1032, which can drive the stirring tube 1033 to rotate with the servo motor 1031. The stirring tube 1033 has two 90-degree elbows at both ends, and the entrances of the elbows are located in the same direction. Water pipe, when the stirring tube 1033 rotates, the inlet of the elbow at one end of the stirring tube 1033 will be in contact with the solution and move, and the solution will be transported into the stirring tube 1033, and then transferred to the elbow at the other end, and the entrance of the elbow at the other end will be It will move away from the solution, so that it will not affect the delivery of the solution from the entrance of the elbow at the other end, and the solution passing through the stirring tube 1033 will be squeezed by the stirring tube 1033 to increase the efficiency of solution mixing.

如图5所示,搅拌管1033共设有五个,搅拌管1033由不锈钢材料制成,通过设有五个搅拌管1033,五个搅拌管1033可以极大地提高对伊维菌素粗品溶液搅拌的效率,并且不锈钢材料的搅拌管1033具有较高的硬度和韧性,同时还具有较高的耐锈蚀性,提高了搅拌管1033的使用寿命。As shown in Figure 5, stirring tube 1033 is provided with five altogether, and stirring tube 1033 is made of stainless steel, by being provided with five stirring tubes 1033, five stirring tubes 1033 can greatly improve the stirring of ivermectin crude product solution. The efficiency, and the stirring tube 1033 made of stainless steel has high hardness and toughness, and also has high corrosion resistance, which improves the service life of the stirring tube 1033.

使用过程简述:首先,将入料泵1021外接在伊维菌素粗品溶液输送设备的输出端,之后将制备机构1通电后启动,在伊维菌素粗品溶液进入到储存罐1011内时,伺服电机1031会将电能转化为旋转的机械能,再将旋转的机械能传递给转动杆1032,转动杆1032就会随着伺服电机1031进行转动,并且带动搅拌管1033进行转动,伊维菌素粗品溶液会随着搅拌管1033的搅动而产生移动,并形成漩涡,同时伊维菌素粗品溶液会在移动时穿过搅拌管1033,在完成对伊维菌素粗品溶液搅拌加工后,可以让结晶机构2对伊维菌素粗品溶液进行结晶加工,在完成对伊维菌素粗品溶液结晶加工后,抽风扇1013可以将储存罐1011内反应后多余的气体排出,直至完成对伊维菌素的制备。Brief description of the use process: First, connect the feeding pump 1021 to the output end of the ivermectin crude product solution delivery equipment, and then start the preparation mechanism 1 after powering on. When the ivermectin crude product solution enters the storage tank 1011, The servo motor 1031 converts electrical energy into rotating mechanical energy, and then transmits the rotating mechanical energy to the rotating rod 1032, and the rotating rod 1032 rotates with the servo motor 1031, and drives the stirring tube 1033 to rotate, and the crude ivermectin solution It will move with the agitation of the stirring tube 1033 and form a vortex. At the same time, the crude ivermectin solution will pass through the stirring tube 1033 while moving. After the stirring process of the crude ivermectin solution is completed, the crystallization mechanism can 2. Carry out crystallization processing on the crude ivermectin solution. After the crystallization processing of the crude ivermectin solution is completed, the exhaust fan 1013 can discharge the excess gas after the reaction in the storage tank 1011 until the preparation of the ivermectin is completed. .

实施例2:Example 2:

参考图6-10,一种高效型抗寄生虫专用伊维菌素制备装置,包括结晶机构2,结晶机构2包括限位组件201、更换组件202、反应组件203和加热组件204,限位组件201栓接在储存组件101的底部,更换组件202卡接在限位组件201的内壁,反应组件203卡接在更换组件202的内壁,加热组件204栓剂诶在反应组件203的内壁,通过设置结晶机构2,限位组件201可以对更换组件202进行支撑和限位,并且可以对伊维菌素粗品溶液进行暂时性储存,更换组件202可以带动反应组件203进行移动,便于将反应组件203从限位组件201内取出和存入,反应组件203可以将晶种进行更换,并对晶种进行暂时性储存,便于晶种与伊维菌素粗品溶液进行结晶化加工处理,加热组件204可以对反应组件203内的晶种和伊维菌素粗品溶液进行加热,从而增加伊维菌素与晶种结晶化加工处理的效率.Referring to Figures 6-10, a high-efficiency ivermectin preparation device dedicated to anti-parasites includes a crystallization mechanism 2, and the crystallization mechanism 2 includes a limiting component 201, a replacement component 202, a reaction component 203 and a heating component 204, and the limiting component 201 is bolted to the bottom of the storage component 101, the replacement component 202 is clamped to the inner wall of the limit component 201, the reaction component 203 is clamped to the inner wall of the replacement component 202, and the heating component 204 suppositories are placed on the inner wall of the reaction component 203. Mechanism 2, the limit component 201 can support and limit the replacement component 202, and can temporarily store the ivermectin crude product solution, the replacement component 202 can drive the reaction component 203 to move, so that the reaction component 203 can be moved from the limit The reaction component 203 can replace the seed crystal and temporarily store the seed crystal, so as to facilitate the crystallization processing of the seed crystal and the crude ivermectin solution. The heating component 204 can react The seed crystal and crude ivermectin solution in the component 203 are heated, thereby increasing the efficiency of crystallization processing of ivermectin and seed crystal.

如图7所示,限位组件201包括限位盒2011、限位滑板2012和存取槽2013,限位盒2011栓接在储存罐1011的底部,限位滑板2012栓接在限位盒2011内壁的前侧和内壁的后侧,存取槽2013开设在限位盒2011的右侧,通过设置限位组件201,限位盒2011可以对更换组件202进行支撑和限位,限位滑板2012可以增加更换组件202在滑动时的稳定性,存取槽2013可以对更换组件202进行暂时性储存,以便于更换组件202对晶种的更换。As shown in Figure 7, the limit assembly 201 includes a limit box 2011, a limit slide plate 2012 and an access slot 2013, the limit box 2011 is bolted to the bottom of the storage tank 1011, and the limit slide plate 2012 is bolted to the limit box 2011 On the front side of the inner wall and the rear side of the inner wall, the access slot 2013 is opened on the right side of the limit box 2011. By setting the limit component 201, the limit box 2011 can support and limit the replacement component 202, and the limit slide plate 2012 The stability of the replacement assembly 202 when sliding can be increased, and the access slot 2013 can temporarily store the replacement assembly 202 so as to facilitate the replacement of the seed crystal by the replacement assembly 202 .

如图8所示,更换组件202包括限位框架2021、限位卡槽2022和封闭板2023,限位框架2021设在限位盒2011的内侧,限位框架2021的前侧和后侧与限位滑板2012的表面滑动连接,限位卡槽2022开设在限位框架2021的内壁,封闭板2023栓接在限位框架2021的右侧,限位框架2021的表面与存取槽2013接触,通过设置更换组件202,限位框架2021可以带动反应组件203进行移动,限位卡槽2022可以对反应组件203进行支撑和限位,便于更换反应组件203,封闭板2023可以与存取槽2013接触,增加限位盒2011内的密封性。As shown in Figure 8, the replacement assembly 202 includes a limiting frame 2021, a limiting slot 2022 and a closing plate 2023. The surface of the position slide plate 2012 is slidingly connected, the limit card slot 2022 is opened on the inner wall of the limit frame 2021, the closing plate 2023 is bolted on the right side of the limit frame 2021, and the surface of the limit frame 2021 is in contact with the access groove 2013. The replacement component 202 is set, the limit frame 2021 can drive the reaction component 203 to move, the limit card slot 2022 can support and limit the reaction component 203, so as to facilitate the replacement of the reaction component 203, the closing plate 2023 can be in contact with the access slot 2013, Increase the sealing in the limit box 2011.

如图9所示,反应组件203包括限位圈板2031、存放盒2032和安装槽2033,存放盒2032卡接在限位卡槽2022的内壁,安装槽2033开设在存放盒2032内壁的底部,限位圈板2031栓剂诶在存放盒2032表面的顶部,限位圈板2031的表面与限位卡槽2022的内壁接触,通过设置反应组件203,限位圈板2031可以增加存放盒2032放置在限位卡槽2022内时的稳定性,存放盒2032可以对晶种进行暂时性储存,以便于对伊维菌素粗品溶液进行结晶化加工处理,安装槽2033可以对加热组件204进行支撑和限位,便于加热组件204对晶种进行辅助性加热,提高结晶加工的效率。As shown in Figure 9, the reaction assembly 203 includes a limit ring plate 2031, a storage box 2032 and an installation groove 2033, the storage box 2032 is clamped on the inner wall of the limit card groove 2022, and the installation groove 2033 is opened on the bottom of the inner wall of the storage box 2032, The limit circle plate 2031 suppository is on the top of the storage box 2032 surface, and the surface of the limit circle plate 2031 is in contact with the inner wall of the limit card groove 2022. By setting the reaction component 203, the limit circle plate 2031 can increase the storage box 2032 and place it on the Stability in the limiting card slot 2022, the storage box 2032 can temporarily store the seed crystals, so as to carry out crystallization processing on the crude ivermectin solution, and the installation slot 2033 can support and limit the heating component 204 position, it is convenient for the heating component 204 to perform auxiliary heating on the seed crystal, so as to improve the efficiency of the crystallization process.

如图10所示,加热组件204包括导热板2041、导热圈2042和加热器2043,导热板2041卡接在安装槽2033的内壁,导热圈2042焊接在导热板2041内壁的两侧,加热器2043栓接在导热板2041的底部,加热器2043的底部贯穿存放盒2032的底部与存放盒2032栓接,通过设置加热组件204,加热器2043可以在通电并启动后,将电能转化为热能,再将热能传递给导热板2041,导热板2041可以将热能传递给导热圈2042,导热板2041和导热圈2042可以将热量传递给伊维菌素粗品溶液,从而增加伊维菌素粗品溶液与晶种结晶化加工处理的效率。As shown in Figure 10, the heating assembly 204 includes a heat conduction plate 2041, a heat conduction ring 2042 and a heater 2043, the heat conduction plate 2041 is clamped on the inner wall of the installation groove 2033, the heat conduction ring 2042 is welded on both sides of the heat conduction plate 2041 inner wall, and the heater 2043 Bolted on the bottom of the heat conducting plate 2041, the bottom of the heater 2043 runs through the bottom of the storage box 2032 and is bolted to the storage box 2032. By setting the heating assembly 204, the heater 2043 can convert electric energy into heat energy after being energized and started. The thermal energy is transferred to the heat conduction plate 2041, and the heat conduction plate 2041 can transfer heat energy to the heat conduction ring 2042, and the heat conduction plate 2041 and the heat conduction ring 2042 can transfer heat to the ivermectin crude product solution, thereby increasing the concentration of the ivermectin crude product solution and the crystal seed The efficiency of crystallization processing.

使用过程简述:首先,将存放盒2032内放入晶种,再将存放盒2032置入限位卡槽2022内,将限位框架2021沿着限位滑板2012置入限位盒2011内,直至封闭板2023与存取槽2013接触并闭合,再将完成搅拌加工的伊维菌素粗品溶液,输送至存放盒2032内,之后将结晶机构2通电并启动,加热器2043会在通电后将电能转化为热能,再将热能传递给导热板2041,导热板2041会将热量传递给导热圈2042,导热板2041和导热圈2042就会将热量传递给伊维菌素粗品溶液,伊维菌素粗品溶液就会与晶种因为热量而逐渐产生结晶反应,直至伊维菌素粗品溶液与晶种完全完成结晶反应后,即可将限位框架2021从存取槽2013内取出,将完成完成制备的伊维菌素取出即可。Brief description of the use process: first, put the storage box 2032 into the seed crystal, then put the storage box 2032 into the limit card slot 2022, put the limit frame 2021 into the limit box 2011 along the limit slide plate 2012, Until the closing plate 2023 contacts and closes the access tank 2013, the crude ivermectin solution that has been stirred and processed is transported to the storage box 2032, and then the crystallization mechanism 2 is powered on and started, and the heater 2043 will turn on the The electric energy is converted into heat energy, and then the heat energy is transferred to the heat conduction plate 2041, the heat conduction plate 2041 will transfer the heat to the heat conduction ring 2042, and the heat conduction plate 2041 and the heat conduction ring 2042 will transfer the heat to the crude ivermectin solution, ivermectin The crude product solution and the seed crystal will gradually produce a crystallization reaction due to heat, until the crude ivermectin solution and the seed crystal completely complete the crystallization reaction, the limiting frame 2021 can be taken out from the access tank 2013, and the preparation will be completed The ivermectin can be taken out.

本具体实施例仅仅是对本发明的解释,其并不是对本发明的限制,本领域技术人员在阅读完本说明书后可以根据需要对本实施例做出没有创造性贡献的修改,但只要在本发明的权利要求范围内都受到专利法的保护。This specific embodiment is only an explanation of the present invention, and it is not a limitation of the present invention. Those skilled in the art can make modifications to this embodiment without creative contribution as required after reading this specification, but as long as they are within the rights of the present invention All claims are protected by patent law.

Claims (10)

1.一种高效型抗寄生虫专用伊维菌素制备装置,包括制备机构(1)和结晶机构(2),其特征在于:所述制备机构(1)包括储存组件(101)、送料组件(102)和搅拌组件(103),所述送料组件(102)连通在储存组件(101)顶部的后侧,所述搅拌组件(103)栓接在储存组件(101)的顶部,所述结晶机构(2)包括限位组件(201)、更换组件(202)、反应组件(203)和加热组件(204),所述限位组件(201)栓接在储存组件(101)的底部,所述更换组件(202)卡接在限位组件(201)的内壁,所述反应组件(203)卡接在更换组件(202)的内壁,所述加热组件(204)栓剂诶在反应组件(203)的内壁。1. A high-efficiency anti-parasitic special ivermectin preparation device, comprising a preparation mechanism (1) and a crystallization mechanism (2), characterized in that: the preparation mechanism (1) includes a storage component (101), a feeding component (102) and a stirring assembly (103), the feeding assembly (102) communicates with the rear side of the top of the storage assembly (101), the stirring assembly (103) is bolted to the top of the storage assembly (101), and the crystallization The mechanism (2) includes a limiting component (201), a replacement component (202), a reaction component (203) and a heating component (204). The limiting component (201) is bolted to the bottom of the storage component (101), so The replacement component (202) is clamped on the inner wall of the limiting component (201), the reaction component (203) is clamped on the inner wall of the replacement component (202), and the heating component (204) suppositories are placed on the reaction component (203) ) of the inner wall. 2.根据权利要求1所述的一种高效型抗寄生虫专用伊维菌素制备装置,其特征在于:所述储存组件(101)包括储存罐(1011)、支撑环(1012)和抽风扇(1013),所述支撑环(1012)栓接在储存罐(1011)的顶部,所述抽风扇(1013)栓接在储存罐(1011)顶部的前侧。2. A high-efficiency anti-parasitic dedicated ivermectin preparation device according to claim 1, characterized in that: the storage assembly (101) includes a storage tank (1011), a support ring (1012) and an exhaust fan (1013), the support ring (1012) is bolted to the top of the storage tank (1011), and the exhaust fan (1013) is bolted to the front side of the top of the storage tank (1011). 3.根据权利要求2所述的一种高效型抗寄生虫专用伊维菌素制备装置,其特征在于:所述送料组件(102)包括入料泵(1021)、储料管(1022)和阀门(1023),所述阀门(1023)连通在储存罐(1011)顶部的后侧,所述储料管(1022)连通在阀门(1023)的顶部,所述入料泵(1021)连通在储料管(1022)的顶部。3. A high-efficiency anti-parasitic special-purpose ivermectin preparation device according to claim 2, characterized in that: the feeding assembly (102) includes a feeding pump (1021), a storage pipe (1022) and Valve (1023), the valve (1023) is connected to the rear side of the top of the storage tank (1011), the storage pipe (1022) is connected to the top of the valve (1023), and the feed pump (1021) is connected to the Top of stock tube (1022). 4.根据权利要求2所述的一种高效型抗寄生虫专用伊维菌素制备装置,其特征在于:所述搅拌组件(103)包括伺服电机(1031)、转动杆(1032)和搅拌管(1033),所述伺服电机(1031)栓接在储存罐(1011)的顶部,所述转动杆(1032)栓接在伺服电机(1031)底部的输出端,所述转动杆(1032)贯穿储存罐(1011)的顶部与储存罐(1011)的顶部转动连接,所述搅拌管(1033)连通在转动杆(1032)的表面。4. A high-efficiency anti-parasitic special ivermectin preparation device according to claim 2, characterized in that: the stirring assembly (103) includes a servo motor (1031), a rotating rod (1032) and a stirring tube (1033), the servomotor (1031) is bolted to the top of the storage tank (1011), the rotating rod (1032) is bolted to the output end of the bottom of the servomotor (1031), and the rotating rod (1032) runs through The top of the storage tank (1011) is rotatably connected with the top of the storage tank (1011), and the stirring tube (1033) communicates with the surface of the rotating rod (1032). 5.根据权利要求2所述的一种高效型抗寄生虫专用伊维菌素制备装置,其特征在于:所述限位组件(201)包括限位盒(2011)、限位滑板(2012)和存取槽(2013),所述限位盒(2011)栓接在储存罐(1011)的底部,所述限位滑板(2012)栓接在限位盒(2011)内壁的前侧和内壁的后侧,所述存取槽(2013)开设在限位盒(2011)的右侧。5. A high-efficiency anti-parasitic special ivermectin preparation device according to claim 2, characterized in that: the limit assembly (201) includes a limit box (2011), a limit slide plate (2012) and the access slot (2013), the limit box (2011) is bolted to the bottom of the storage tank (1011), and the limit slide plate (2012) is bolted to the front side and the inner wall of the limit box (2011) On the rear side, the access slot (2013) is opened on the right side of the limit box (2011). 6.根据权利要求5所述的一种高效型抗寄生虫专用伊维菌素制备装置,其特征在于:所述更换组件(202)包括限位框架(2021)、限位卡槽(2022)和封闭板(2023),所述限位框架(2021)设在限位盒(2011)的内侧,所述限位框架(2021)的前侧和后侧与限位滑板(2012)的表面滑动连接,所述限位卡槽(2022)开设在限位框架(2021)的内壁,所述封闭板(2023)栓接在限位框架(2021)的右侧,所述限位框架(2021)的表面与存取槽(2013)接触。6. A high-efficiency anti-parasitic special ivermectin preparation device according to claim 5, characterized in that: the replacement component (202) includes a limiting frame (2021), a limiting card slot (2022) and a closing plate (2023), the limit frame (2021) is arranged on the inside of the limit box (2011), and the front side and the rear side of the limit frame (2021) slide with the surface of the limit slide plate (2012) connection, the limit card slot (2022) is opened on the inner wall of the limit frame (2021), the closure plate (2023) is bolted to the right side of the limit frame (2021), and the limit frame (2021) The surface is in contact with the access groove (2013). 7.根据权利要求6所述的一种高效型抗寄生虫专用伊维菌素制备装置,其特征在于:所述反应组件(203)包括限位圈板(2031)、存放盒(2032)和安装槽(2033),所述存放盒(2032)卡接在限位卡槽(2022)的内壁,所述安装槽(2033)开设在存放盒(2032)内壁的底部,所述限位圈板(2031)栓剂诶在存放盒(2032)表面的顶部,所述限位圈板(2031)的表面与限位卡槽(2022)的内壁接触。7. A high-efficiency anti-parasitic special-purpose ivermectin preparation device according to claim 6, characterized in that: the reaction assembly (203) includes a spacer plate (2031), a storage box (2032) and The installation slot (2033), the storage box (2032) is clamped on the inner wall of the limit card slot (2022), the installation slot (2033) is opened at the bottom of the storage box (2032) inner wall, and the limit ring plate (2031) The suppository is on the top of the surface of the storage box (2032), and the surface of the limiting ring plate (2031) is in contact with the inner wall of the limiting card slot (2022). 8.根据权利要求7所述的一种高效型抗寄生虫专用伊维菌素制备装置,其特征在于:所述加热组件(204)包括导热板(2041)、导热圈(2042)和加热器(2043),所述导热板(2041)卡接在安装槽(2033)的内壁,所述导热圈(2042)焊接在导热板(2041)内壁的两侧,所述加热器(2043)栓接在导热板(2041)的底部,所述加热器(2043)的底部贯穿存放盒(2032)的底部与存放盒(2032)栓接。8. A high-efficiency anti-parasitic special ivermectin preparation device according to claim 7, characterized in that: the heating assembly (204) includes a heat conducting plate (2041), a heat conducting ring (2042) and a heater (2043), the heat conducting plate (2041) is clamped on the inner wall of the installation groove (2033), the heat conducting ring (2042) is welded on both sides of the inner wall of the heat conducting plate (2041), and the heater (2043) is bolted At the bottom of the heat conducting plate (2041), the bottom of the heater (2043) passes through the bottom of the storage box (2032) and is bolted to the storage box (2032). 9.根据权利要求4所述的一种高效型抗寄生虫专用伊维菌素制备装置,其特征在于:所述搅拌管(1033)共设有五个,所述搅拌管(1033)由不锈钢材料制成。9. A kind of high-efficiency anti-parasitic special-purpose ivermectin preparation device according to claim 4, is characterized in that: described agitating tube (1033) is provided with five altogether, and described agitating tube (1033) is made of stainless steel material. 10.一种高效型抗寄生虫专用伊维菌素的制备工艺,其特征在于:包括以下步骤:10. A preparation process of high-efficiency anti-parasitic special ivermectin, characterized in that: comprising the following steps: S1.入料搅拌:首先,将入料泵(1021)外接在伊维菌素粗品溶液输送设备的输出端,之后将制备机构(1)通电后启动,在伊维菌素粗品溶液进入到储存罐(1011)内时,伺服电机(1031)会将电能转化为旋转的机械能,再将旋转的机械能传递给转动杆(1032),转动杆(1032)就会随着伺服电机(1031)进行转动,并且带动搅拌管(1033)进行转动,伊维菌素粗品溶液会随着搅拌管(1033)的搅动而产生移动,并形成漩涡,同时伊维菌素粗品溶液会在移动时穿过搅拌管(1033),在完成对伊维菌素粗品溶液搅拌加工后,可以让结晶机构(2)对伊维菌素粗品溶液进行结晶加工,在完成对伊维菌素粗品溶液结晶加工后,抽风扇(1013)可以将储存罐(1011)内反应后多余的气体排出,直至完成对伊维菌素的制备;S1. Feeding and stirring: firstly, connect the feeding pump (1021) externally to the output end of the ivermectin crude product solution delivery equipment, and then start the preparation mechanism (1) after powering on, and enter the ivermectin crude product solution into the storage When inside the tank (1011), the servo motor (1031) will convert electrical energy into rotational mechanical energy, and then transmit the rotational mechanical energy to the rotating rod (1032), and the rotating rod (1032) will rotate with the servo motor (1031) , and drive the stirring tube (1033) to rotate, the ivermectin crude product solution will move with the stirring of the stirring tube (1033), and form a vortex, and the ivermectin crude product solution will pass through the stirring tube while moving (1033), after completing the stirring process to the ivermectin crude product solution, the crystallization mechanism (2) can be allowed to carry out the crystallization process to the ivermectin crude product solution, and after completing the crystallization process to the ivermectin crude product solution, the exhaust fan (1013) The excess gas after the reaction in the storage tank (1011) can be discharged until the preparation of ivermectin is completed; S2.升温结晶:首先,将存放盒(2032)内放入晶种,再将存放盒(2032)置入限位卡槽(2022)内,将限位框架(2021)沿着限位滑板(2012)置入限位盒(2011)内,直至封闭板(2023)与存取槽(2013)接触并闭合,再将完成搅拌加工的伊维菌素粗品溶液,输送至存放盒(2032)内,之后将结晶机构(2)通电并启动,加热器(2043)会在通电后将电能转化为热能,再将热能传递给导热板(2041),导热板(2041)会将热量传递给导热圈(2042),导热板(2041)和导热圈(2042)就会将热量传递给伊维菌素粗品溶液,伊维菌素粗品溶液就会与晶种因为热量而逐渐产生结晶反应,直至伊维菌素粗品溶液与晶种完全完成结晶反应后,即可将限位框架(2021)从存取槽(2013)内取出,将完成完成制备的伊维菌素取出即可。S2. Heating crystallization: First, put the storage box (2032) into the seed crystal, then put the storage box (2032) into the limit card slot (2022), and place the limit frame (2021) along the limit slide plate ( 2012) into the limit box (2011) until the closing plate (2023) contacts and closes the access tank (2013), then the crude ivermectin solution that has been stirred and processed is transported to the storage box (2032) , and then the crystallization mechanism (2) is energized and started, the heater (2043) will convert the electric energy into heat energy after energization, and then transfer the heat energy to the heat conduction plate (2041), and the heat conduction plate (2041) will transfer heat to the heat conduction ring (2042), the heat conduction plate (2041) and the heat conduction ring (2042) will transfer heat to the ivermectin crude product solution, and the ivermectin crude product solution will gradually produce a crystallization reaction with the crystal seed because of the heat until the ivermectin After the crystallization reaction between the crude bacterin solution and the seed crystal is completely completed, the limiting frame (2021) can be taken out from the access tank (2013), and the prepared ivermectin can be taken out.
CN202310436310.7A 2023-04-23 2023-04-23 A highly efficient anti-parasitic ivermectin preparation device and preparation process Active CN116492958B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310436310.7A CN116492958B (en) 2023-04-23 2023-04-23 A highly efficient anti-parasitic ivermectin preparation device and preparation process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202310436310.7A CN116492958B (en) 2023-04-23 2023-04-23 A highly efficient anti-parasitic ivermectin preparation device and preparation process

Publications (2)

Publication Number Publication Date
CN116492958A true CN116492958A (en) 2023-07-28
CN116492958B CN116492958B (en) 2025-05-16

Family

ID=87327858

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202310436310.7A Active CN116492958B (en) 2023-04-23 2023-04-23 A highly efficient anti-parasitic ivermectin preparation device and preparation process

Country Status (1)

Country Link
CN (1) CN116492958B (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140083191A (en) * 2012-12-24 2014-07-04 재단법인 포항산업과학연구원 Crystallization apparatus
CN209237406U (en) * 2018-12-21 2019-08-13 高安市兆鑫陶瓷辅料有限公司 A kind of Chemical Manufacture continuous crystallisation device
CN213854148U (en) * 2020-12-08 2021-08-03 南京康川济医药科技有限公司 Raw materials proportioning equipment is used in production of oral solid preparation
CN216320066U (en) * 2021-09-02 2022-04-19 河南中硼新材料有限公司 Adjustable crystallization cooling device for nitrogen-potassium compound fertilizer
CN218359268U (en) * 2022-11-01 2023-01-24 山东济坤生物制药有限公司 Preparation equipment for splitting dexibuprofen

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140083191A (en) * 2012-12-24 2014-07-04 재단법인 포항산업과학연구원 Crystallization apparatus
CN209237406U (en) * 2018-12-21 2019-08-13 高安市兆鑫陶瓷辅料有限公司 A kind of Chemical Manufacture continuous crystallisation device
CN213854148U (en) * 2020-12-08 2021-08-03 南京康川济医药科技有限公司 Raw materials proportioning equipment is used in production of oral solid preparation
CN216320066U (en) * 2021-09-02 2022-04-19 河南中硼新材料有限公司 Adjustable crystallization cooling device for nitrogen-potassium compound fertilizer
CN218359268U (en) * 2022-11-01 2023-01-24 山东济坤生物制药有限公司 Preparation equipment for splitting dexibuprofen

Also Published As

Publication number Publication date
CN116492958B (en) 2025-05-16

Similar Documents

Publication Publication Date Title
CN213147241U (en) Drying equipment for chemical raw material processing
CN116492958A (en) Efficient type device and process for preparing ivermectin special for antiparasitic
CN218608119U (en) Medicinal acid crystallization kettle
CN216778815U (en) Production equipment of nano metal copper oxide
CN221217260U (en) Lithium electricity waste water evaporation crystallization device
CN216445231U (en) Mud high temperature drying equipment
CN207839003U (en) A preparation device for circulating water corrosion and scale inhibitors
CN118308126A (en) Cooling device for biomass pyrolysis matters
CN115121034B (en) A kind of pretreatment device for salicylonitrile solvent recovery and its processing method
CN223376323U (en) Preparation equipment of expandable graphite
CN115624948A (en) A kind of vinylene carbonate synthesis reaction system and its synthesis reaction method
CN210473112U (en) High-efficient extraction separator of chemical engineering
CN223874455U (en) Hydrazine hydrochloride and hydrazine hydrate recovery unit and methyl hydrazine production facility
CN215196840U (en) A liquid material conveying system for chemical production
CN204693822U (en) A kind of constant temperature high efficiency agitator type liquid heat-conducting medium firing equipment
CN222677177U (en) Concentrating device for chemical product production
CN214346479U (en) Reaction device for zirconia powder
CN217367168U (en) Magnesium chloride extraction element
CN222460294U (en) Expanded perlite preheating device
CN223570730U (en) A chemical production reactor equipped with a heat recovery structure
CN218307904U (en) Horizontal reation kettle is used in emulsion production with rotation type heating function
CN223456285U (en) A PA66 composite material processing device that facilitates uniform heating
CN217016175U (en) Reaction feeding preheater with even structure
CN221667354U (en) Nylon salt solution online sampling system
CN220116462U (en) Experimental device for biomass pyrolysis process

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant