CN116459291A - Preparation method of Chinese herbal medicine plant antihypertensive ferment - Google Patents

Abstract

The invention provides a method for preparing Chinese herbal medicine plant antihypertensive ferment, which has the beneficial effects that: the selenium-enriched heart-nourishing vegetables cultivated by the company and Chinese herbal medicine plant antihypertensive ferment obtained finally contains physiological active substances of the Chinese herbal medicine, can produce the required effects of reducing blood pressure, tonifying kidney, enriching blood and the like, retains the nutrition and sufficient selenium elements of the selenium-enriched heart-nourishing vegetables, and is also rich in various vitamins, rich amino acids and various beneficial trace elements produced by strains and matrixes in the fermentation process, the combination of the nutritional ingredients is reasonable, and the nutritional ingredients are easy to be absorbed and utilized by organisms, so that the purpose of homology of medicine and food is achieved.

Description

Preparation method of Chinese herbal medicine plant antihypertensive ferment

Technical Field

The technology belongs to the technical field of biological fermentation, and relates to a method for preparing Chinese herbal medicine plant antihypertensive ferment.

Background

Loranthus mulberry mistletoe is bitter and sweet in flavor and neutral in nature. Has the functions of dispelling wind-damp, tonifying liver and kidney, strengthening tendons and bones, and soothing fetus, and is recorded in the book of materia medica true: herba Taxilli, with the number of kidney-tonifying and blood-replenishing main agents. The kidney is the main bone, and the bitter taste in the kidney is the reinforcing effect of the kidney, which is the powerful tendons and bones. Blood is nourished by the blood, and it is enough to be irrigated with shadow instead of withered and shed. Therefore, it is mainly indicated for lumbago, muscle and bone diseases, abortion, sore and skin rheumatism. "

Semen Cassiae is dry mature seed of Cassia Torae semen or Cassia tora of Leguminosae, and is named as having eyesight improving effect. Harvesting mature fruits in autumn, sun drying, threshing seeds, and removing impurities. Semen Cassiae is bitter, sweet and salty in taste, and slightly cold in nature, entering liver, kidney and large intestine meridians; relaxing bowel, reducing blood lipid, improving eyesight, and treating constipation, hyperlipidemia and hypertension. Clearing liver-fire, improving vision, promoting diuresis, relaxing bowels, reducing blood pressure and blood lipid.

Ecliptae herba has sweet and sour taste, and cold nature, and has effects of nourishing liver and kidney, cooling blood and stopping bleeding. It is often used for deficiency of liver-yin and kidney-yin, loosening of teeth, premature graying of hair, dizziness, tinnitus, soreness of waist and knees, yin deficiency, blood heat, hematemesis, epistaxis, hematuria, bloody dysentery, metrorrhagia, hemorrhage due to trauma, and hemorrhage.

The mature fruit of glossy privet is sun-dried to be a traditional Chinese medicine glossy privet fruit, has sweet and bitter taste and cool nature, can improve eyesight, blacken hair, nourish liver and kidney, and also has the effects of reducing blood sugar, reducing blood fat, resisting arteriosclerosis, resisting liver injury, resisting cancer, resisting mutation and the like.

The ferment is a functional fermentation product formed by fermenting animals, plants or fungi by microorganisms. The edible plant ferment defined in the national standard "enzyme product classification guide" (QB/T5324) is an edible ferment product which is prepared from plants which can be used for food processing as main raw materials, and auxiliary materials or no auxiliary materials, and contains specific bioactive components and can be eaten by human beings through microbial fermentation, so that a large number of plant fermentation products obtained through microbial fermentation in the market belong to the category of edible ferment. This is a regulation from the viewpoint of industrial application and industrial practice, and is advantageous for the development of the enzyme industry. However, this also offers the possibility of many low quality enzyme products coming into the market. Such as: simple fermentation of single lactic acid bacteria, yeast, acetic acid bacteria, etc., while formally satisfying the concept of ferments, these products have not fully embodied the technical connotation of ferments. So that the effect is not ideal.

In recent years, more and more flavone polyphenols in foods are studied, and are important functional substances. Brass polyphenol is widely existing in various plants and fruits, and has the effects of resisting bacteria, diminishing inflammation, enhancing immunity, improving cardiovascular, protecting liver, resisting tumor, resisting cancer and the like besides stronger free radical scavenging capability.

The heart-nourishing vegetables are also called high-calcium heart-nourishing vegetables, heart-nourishing grass, heart-saving vegetables, sedum aizoon, high-calcium vegetables, gynura segetum, gynura procumbens, and the like, and are perennial herbaceous plants and all-herbal medicines are homologous in food.

The tender stem leaves of the heart-nourishing vegetable are rich in nutrition, each 100g of the tender stem leaves contains 2.1g of protein, 0.87g of amino acid, 1.5g of total sugar, 0.78g of fat, 2.4g of dietary fiber, 95mg of vitamin C, 500mg of calcium, 69mg of phosphorus, 3.2mg of iron, 2.8mg of carotene, 900mg of niacin and the like, and simultaneously contains rich alkaloids, oleanolic acid, sitosterol, sedum-heptose, flavonoids, organic acids and other physiological active substances, so that the heart-nourishing vegetable is an ideal green food for supplementing calcium for people. The heart-nourishing vegetable mainly eats tender stem and leaf, has the effects of clearing heat and detoxicating, stopping bleeding and relieving cough, reducing vascular purpura, improving the immunity and antiviral ability of human body, purging pathogenic fire, cooling blood and diminishing inflammation, promoting the production of body fluid and the like.

The Chinese medicinal treatises of the famous and precious Chinese medicinal herbs, the modern Chinese medicinal clinical handbook and the like prove that the heart-nourishing vegetable has the functions of reducing blood pressure and blood fat, promoting blood circulation by removing blood stasis, tonifying qi and strengthening heart, calming heart and liver, clearing heat and cooling blood, has the effects of reducing the toxicity of amphetamine and expanding coronary arteries, has better curative effects on hematemesis, hemoptysis, dysphoria and insomnia, palpitation and hysteria, and can achieve the effects of detumescence and hemostasis by external application. The whole body of the heart-nourishing vegetable can be used as a medicine, is a plant with very high medicinal value, can survive easily, does not need to spray medicine to control insects, and is an absolute pure pollution-free green vegetable.

The heart-nourishing vegetable is perennial, is planted for thirty years without being planted again, is cold-resistant, drought-resistant, saline-alkali-resistant, barren-resistant and sand-resistant, is suitable for planting in various soils, has high survival rate and happy yield, and is a high-nutrition vegetable very suitable for people.

Selenium is a trace element necessary for human body, has the functions of resisting oxidation and aging, and can cause illness and aging of the human body once the human body is subjected to oxidation injury, and the selenium can activate the oxidation resisting system of the human body, control the oxidation injury of the human body and prevent diseases. Selenium has antioxidant effect of more than 500 times of vitamin E.

Selenium also can protect and repair cells and improve the oxygen carrying capacity of red blood cells, thereby achieving the effect of improving body immunity. In addition, selenium can also play roles in decomposing in vivo toxin, removing harmful substances in liver, preventing cardiovascular and cerebrovascular diseases, etc. Of course, selenium plays a very critical role in human anticancer.

The medicinal materials, plants and the like are helpful for the body, but the effect is lower in common use, and various elements required by the medicinal materials, plants and the like are difficult to be integrated.

Disclosure of Invention

In view of the above, the invention provides a preparation method of the Chinese herbal medicine plant antihypertensive ferment, which is characterized in that selenium-rich heart-nourishing vegetables successfully cultivated by using the unique technology of the company are matched with a plurality of effective medicinal materials, and the finally obtained Chinese herbal medicine plant antihypertensive ferment contains physiological active substances of the Chinese herbal medicine, can generate the required effects of reducing blood pressure, tonifying kidney, enriching blood and the like, retains the nutrition and abundant selenium elements of the selenium-rich heart-nourishing vegetables, is also rich in various vitamins, abundant amino acids and various beneficial trace elements generated by strains and matrixes in the fermentation process, has reasonable combination of the nutritional ingredients, is easy to be absorbed and utilized by organisms, and achieves the purpose of homology of medicine and food.

Drawings

1. The preparation process of the Chinese herbal medicine plant antihypertensive ferment is as shown in fig. 1:

b1-stock

B2-decoction medicine material

B3-preparing selenium-enriched heart-nourishing vegetable pulp

B4-preparation of enzymolysis bacterial liquid

B5-enzymolysis

B6-filtration

B7-inoculation of probiotics

B8-acidification

B9-curing

B10-filtration

B11-package

Detailed Description

The technical solutions of the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only one embodiment of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

The preparation method of the Chinese herbal medicine plant antihypertensive ferment shown in the attached figure 1 comprises the following steps:

b1, preparing materials

Loranthus mulberry mistletoe 5kg

10kg of semen cassiae

Ecliptae herba 3kg

Glossy privet fruit 3kg

Selenium-rich heart-nourishing vegetable 50kg

Brown sugar 20kg

Fruit wine yeast 100g

15-strain composite probiotics (200 hundred million/g) 100g

180g of active acetic acid bacteria (50 hundred million/g)

Purified water is a plurality of.

B2, treating the medicinal materials

Pulverizing herba Taxilli prepared in step B1, adding 10kg purified water, boiling with strong fire, and decocting with slow fire for 2 hr;

pulverizing semen Cassiae, ecliptae herba and fructus Ligustri Lucidi respectively.

B3, preparing selenium-enriched heart-nourishing vegetable pulp

And (3) cleaning the selenium-enriched heart-nourishing vegetables prepared in the step (B1), draining water, crushing, and obtaining juice which is the selenium-enriched heart-nourishing vegetable pulp, and sterilizing for later use.

B4, preparing enzymolysis bacterial liquid

Dissolving the fruit wine yeast prepared in the step B1 into 1kg of purified water, and placing the purified water in a constant temperature box at 25 ℃ for 48 hours to obtain enzymolysis bacterial liquid.

B5, enzymolysis

Mixing the medicinal materials treated by the B2 with the medicinal slurry, stirring uniformly, adding the selenium-enriched heart-nourishing vegetable slurry prepared by the B3, stirring uniformly again, adding the brown sugar prepared by the B1 and the enzymolysis bacterial liquid prepared by the B4 respectively (stirring uniformly after each addition), fermenting integrally in a greenhouse at 20-35 ℃ for 30 days, stirring for 1-2 times every day for the first 15 days, and stirring once every two days for the last 15 days. After one month observation, if no solid matter is floating out, the fermentation is mature, namely the enzymolysis is finished, and if the solid matter is still floating out, the fermentation is continued until no solid matter is floating out.

B6, filtering

And (3) carrying out rough filtration on the product obtained after the enzymolysis in the step B5, filtering out solids, and only leaving slurry, wherein the slurry is about 90 kg.

B7, inoculating probiotics

The 15-bacteria composite probiotics prepared in B1 are added into the slurry filtered in B6, and then the mixture is placed in a greenhouse at 25-35 ℃ for fermentation for 24 hours.

B8, acidification

Adding active acetic acid bacteria prepared in B1 into the slurry obtained after inoculating probiotics in B7, fermenting in a greenhouse at 20-35 ℃ for 30 days, stirring once every ten days, and stirring once every two days.

B9, curing

And (3) placing the acidified liquid in the step B8 into a room temperature storage room for curing for three months.

B10, filter

Filtering the cured slurry in step B9 once with 300-mesh filter cloth to obtain the finished product.

B11, packaging

And (3) sterilizing the finished antihypertensive ferment by ultraviolet rays, and sealing and packaging.

The Chinese herbal medicine plant antihypertensive ferment prepared by the steps not only contains physiological active substances of Chinese herbal medicines per se, can generate the required effects of reducing blood pressure, tonifying kidney, enriching blood and the like, but also reserves the nutrition of selenium-enriched heart-nourishing vegetables and enough selenium elements, is also rich in various vitamins, rich amino acids and various beneficial microelements generated in the fermentation process of strains and matrixes, has reasonable combination of the nutritional ingredients, is extremely easy to be absorbed and utilized by organisms, achieves the aim of homology of medicine and food, and is an excellent choice no matter being used by oneself or shared with friends or sent for a holiday.

Claims (2)

1. A method for preparing Chinese herbal medicine plant antihypertensive ferment is characterized in that Chinese herbal medicine with antihypertensive effect and selenium-enriched heart-nourishing vegetable cultivated by the company are used as main raw materials, and the ferment obtained by the multi-bacteria compound fermentation process not only contains physiological active substances of the Chinese herbal medicine, can generate the required antihypertensive, kidney-tonifying and blood-enriching effects, and retains the nutrition and sufficient selenium elements of the selenium-enriched heart-nourishing vegetable, but also contains a plurality of vitamins, abundant amino acids and a plurality of beneficial trace elements generated by strains and matrixes in the fermentation process, and the nutritional elements are reasonably combined and are easy to be absorbed and utilized by organisms, so that the purpose of homology of medicine and food is achieved.

2. The method for preparing the herbal antihypertensive ferment according to claim 1, wherein the steps of:

b1, preparing materials

Loranthus mulberry mistletoe 5kg

10kg of semen cassiae

Ecliptae herba 3kg

Glossy privet fruit 3kg

Selenium-rich heart-nourishing vegetable 50kg

Brown sugar 20kg

Fruit wine yeast 100g

15-strain composite probiotics (200 hundred million/g) 100g

180g of active acetic acid bacteria (50 hundred million/g)

Purified water is a plurality of.

B2, treating the medicinal materials

Pulverizing herba Taxilli prepared in step B1, adding 10kg purified water, boiling with strong fire, and decocting with slow fire for 2 hr;

pulverizing semen Cassiae, ecliptae herba and fructus Ligustri Lucidi respectively.

B3, preparing selenium-enriched heart-nourishing vegetable pulp

And (3) cleaning the selenium-enriched heart-nourishing vegetables prepared in the step (B1), draining water, crushing, and obtaining juice which is the selenium-enriched heart-nourishing vegetable pulp, and sterilizing for later use.

B4, preparing enzymolysis bacterial liquid

Dissolving the fruit wine yeast prepared in the step B1 into 1kg of purified water, and placing the purified water in a constant temperature box at 25 ℃ for 48 hours to obtain enzymolysis bacterial liquid.

B5, enzymolysis

Mixing the medicinal materials treated by the B2 with the medicinal slurry, stirring uniformly, adding the selenium-enriched heart-nourishing vegetable slurry prepared by the B3, stirring uniformly again, adding the brown sugar prepared by the B1 and the enzymolysis bacterial liquid prepared by the B4 respectively (stirring uniformly after each addition), fermenting integrally in a greenhouse at 20-35 ℃ for 30 days, stirring for 1-2 times every day for the first 15 days, and stirring once every two days for the last 15 days. After one month observation, if no solid matter is floating out, the fermentation is mature, namely the enzymolysis is finished, and if the solid matter is still floating out, the fermentation is continued until no solid matter is floating out.

B6, filtering

And (3) carrying out rough filtration on the product obtained after the enzymolysis in the step B5, filtering out solids, and only leaving slurry, wherein the slurry is about 90 kg.

B7, inoculating probiotics

The 15-bacteria composite probiotics prepared in B1 are added into the slurry filtered in B6, and then the mixture is placed in a greenhouse at 25-35 ℃ for fermentation for 24 hours.

B8, acidification

Adding active acetic acid bacteria prepared in B1 into the slurry obtained after inoculating probiotics in B7, fermenting in a greenhouse at 20-35 ℃ for 30 days, stirring once every ten days, and stirring once every two days.

B9, curing

And (3) placing the acidified liquid in the step B8 into a room temperature storage room for curing for three months.

B10, filter

Filtering the cured slurry in step B9 once with 300-mesh filter cloth to obtain the finished product.

B11, packaging

And (3) sterilizing the finished antihypertensive ferment by ultraviolet rays, and sealing and packaging.