CN116370780A - High-flow respiratory humidification therapeutic apparatus and use method thereof - Google Patents

Abstract

The invention provides a high-flow respiratory humidification therapeutic apparatus and a use method thereof, wherein the high-flow respiratory humidification therapeutic apparatus comprises an air-oxygen mixing tank, a fan, a nasal oxygen tube, an end-tidal carbon dioxide monitoring module, a gas collecting tube and a controller; an air inlet of the air-oxygen mixing tank is respectively communicated with an air inlet end and an oxygen inlet end, an air outlet of the air-oxygen mixing tank is communicated with a nasal oxygen pipe through a fan, and an electric control valve for adjusting oxygen flow is arranged on the oxygen inlet end; the end-expiratory carbon dioxide monitoring module is internally provided with a negative pressure active gas sampling unit which is communicated with the nasal oxygen tube through a gas collecting tube; the electric control valve, the fan and the end-expiratory carbon dioxide monitoring module are all in communication connection with the controller. The method can accurately monitor the end-tidal carbon dioxide in the high-flow respiratory humidification treatment process, and can reduce oxygen consumption.

Description

A high-flow respiratory humidification therapeutic instrument and its application method

technical field

The invention relates to the technical field of respiratory therapeutic apparatus, in particular to a high-flow respiratory humidification therapeutic apparatus and its usage method.

Background technique

High-flow respiratory humidification therapy device, through the high-flow special nasal cannula or other patient interface, the heated and humidified air-oxygen mixture is delivered to the patient at a high flow rate, and it is often used clinically for mild to moderate hypoxemia, such as hypoxemia. Oxygen respiratory failure, such as ARDS, pneumonia, pulmonary fibrosis, cardiogenic pulmonary edema, etc. It has a positive therapeutic effect on patients with simple hypoxic respiratory failure (Type I respiratory failure), and also has a certain therapeutic effect on some patients with mild hypoxia and hypercapnia (Type II respiratory failure). The patient's high-flow respiratory humidification therapeutic instrument has a significant therapeutic effect. The high-flow respiratory humidification therapy device does not need to use a closed face mask or nasal mask, which has good user compliance and good physical comfort; it can provide a stable high oxygen concentration, and quickly and effectively improve blood oxygen; wash away the physiological anatomy through high flow Dead space, reducing carbon dioxide rebreathing; sufficient humidification and warming, so that the mucus and cilia cleaning function of the airway is in the best state.

In the process of oxygen inhalation therapy, it is necessary to pay close attention to the partial pressure of carbon dioxide in arterial blood (PaCO ₂ ), but the detection of partial pressure of carbon dioxide in arterial blood needs to collect arterial blood, so it is difficult to monitor in real time, while the end-tidal carbon dioxide concentration (ETCO ₂ ) can reflect PaCO ₂ , so the monitoring of ETCO ₂ is of great significance in the process of high-flow respiratory humidification therapy _performed by the high-flow respiratory humidification therapy device. Adjust the treatment plan in time. In order to realize the accurate monitoring of end-tidal carbon dioxide, the existing method of end-tidal carbon dioxide monitoring needs to fully collect the exhaled gas of the human body, but in the process of high-flow respiratory humidification treatment, the continuous input of high-flow air-oxygen mixed gas, generally The flow rate is greater than 40L/min, while the single exhalation/inhalation gas tidal volume of an adult is only about 0.5L (duration 2-3s), so the input gas flow rate is at least 3 times the exhaled gas flow rate, and the input air flow will "blow away" the human body Exhaled gas seriously affects the monitoring of end-tidal carbon dioxide.

Moreover, the high-flow respiratory humidification therapy device consumes a lot of oxygen during its operation. For emergency patients with type I respiratory failure, the initial gas flow of HFNC (high-flow nasal humidification oxygen therapy) is set to 40-60L/min , the initial oxygen concentration is 100%; for emergency patients with type II respiratory failure, the initial flow rate of HFNC gas is set to 50-60L/min, and the initial oxygen concentration is 90%. In the past, the design of the oxygen supply system of the hospital center was based on the standard design of 5-10 (L/min) per bed for emergency/critical care beds, and 3-5 (L/min) per bed for ordinary beds, with an oxygen flow consumption of 40-60 L/min. It is 10-20 times that of the hospital's original oxygen supply system, so it will bring great challenges to the hospital's oxygen supply system. At present, some hospitals that use more high-flow humidification therapy instruments have already exposed the problem of insufficient oxygen supply. Oxygen concentrators are also one of the oxygen sources for high-flow respiratory humidification therapy, but the flow rate of the current mainstream portable oxygen concentrators is generally 1-10L/min. needs for chemotherapy.

For this reason, there is an urgent need for a high-flow respiratory humidification therapeutic apparatus capable of monitoring end-tidal carbon dioxide and reducing oxygen consumption.

Contents of the invention

(1) Technical problems to be solved

In view of the problems existing in the above-mentioned technologies, the present invention solves them at least to a certain extent. Therefore, the first object of the present invention is to provide a high-flow respiratory humidification therapy device, which can accurately monitor end-tidal carbon dioxide and reduce oxygen consumption during the high-flow respiratory humidification therapy.

The second object of the present invention is to propose a method for using the above-mentioned high-flow respiratory humidification therapeutic apparatus.

(2) Technical solution

In order to achieve the above object, the main technical solutions adopted in the present invention include:

In the first aspect, the present invention provides a high-flow respiratory humidification treatment instrument, including an air-oxygen mixing tank, a fan, a nasal oxygen tube, an end-tidal carbon dioxide monitoring module, a gas collection tube and a controller; the air intake of the air-oxygen mixing tank The mouth is connected with the air inlet port and the oxygen inlet port respectively, the air outlet of the air-oxygen mixing tank is connected with the nasal oxygen tube through the fan, and the oxygen inlet port is provided with an electric control valve for adjusting the oxygen flow rate; the end-tidal carbon dioxide monitoring The module has a built-in negative pressure active gas sampling unit, and the negative pressure active gas sampling unit is connected to the nasal oxygen tube through the gas collection tube; the electronic control valve, fan and end-tidal carbon dioxide monitoring module are all connected to the controller by communication.

Optionally, the nasal oxygen tube includes a main body, a tubular air guide hole, and a tubular first air outlet and a tubular second air outlet respectively corresponding to the left and right nostrils of the human body; the air guide hole, the first air outlet and the second air outlet are all connected to the main body, The main body is also provided with an air intake hole through which the blower sends air to the nasal oxygen tube, and the main body communicates with the gas collection pipe through the air guide hole.

Optionally, the main body is tubular, the first air outlet and the second air outlet are both arranged on the first side of the main body, and both the first air outlet and the second air outlet are connected to the main body, and the air guide hole is arranged at one end of the main body , and the air guide hole communicates with the main body.

Optionally, the high-flow respiratory humidification therapeutic instrument also includes an air intake channel, a humidification tank, a heating module, a heating tube and a connecting air guide tube; the air outlet of the air-oxygen mixing tank communicates with the air inlet of the air intake channel through a fan, The air outlet of the air inlet passage is connected with the air inlet of the humidification tank, the air outlet of the humidification tank is connected with the air inlet of the heating pipe, the air outlet of the heating pipe is connected with the air inlet connected with the air guide pipe, and the air outlet connected with the air guide pipe The air outlet communicates with the nasal oxygen tube through the air inlet, and the heating module is used to heat the pure water in the humidification tank to evaporate the water; both the heating module and the heating tube are connected to the controller in communication.

Optionally, the sampling flow rate of the negative pressure active gas sampling unit is 100mL/min-250mL/min, the inner diameter of the gas collection tube is 0.8-2mm, and the length of the gas collection tube is less than 1.5m.

Optionally, the sampling flow rate of the negative pressure active gas sampling unit is 150mL/min-250mL/min, and the inner diameter of the gas collection tube is 0.8-1.5mm.

Optionally, the nasal oxygen tube includes a main body, a tubular air guide hole, and a tubular first air outlet and a tubular second air outlet respectively corresponding to the left and right nostrils of the human body; both the first air outlet and the second air outlet are connected to the main body, and the main body also has An air inlet is provided, and the fan supplies air to the nasal oxygen tube through the air inlet. The gas outlet of the stomata is communicated with the gas collection pipe.

In a second aspect, the present invention provides a method for using a high-flow respiratory humidification therapeutic instrument, comprising the following steps:

S1. During the process of high-flow respiratory humidification treatment for patients by the high-flow respiratory humidification therapeutic instrument, the end-tidal carbon dioxide monitoring module continuously samples and monitors the end-tidal carbon dioxide concentration to obtain the end-tidal carbon dioxide monitoring signal;

S2. Obtain the current respiration rate of the patient according to the end-tidal carbon dioxide monitoring signal, and obtain the current end-tidal carbon dioxide monitoring period according to the respiration rate;

S3. Starting from the moment when the current respiration rate is obtained, according to the current respiration rate, the controller reduces or stops the gas flow at the oxygen inlet end through the electric control valve at the end of each breath inhalation, and before the inhalation of each breath begins The controller restores the air supply flow at the oxygen intake end through the electronic control valve; starting from the moment when the current breathing rate is obtained, according to the current breathing rate, when the number of breathing reaches the current end-tidal carbon dioxide monitoring cycle, it is controlled at the end of the next breath. The controller reduces or stops the air supply flow of the fan, and the end-tidal carbon dioxide monitoring module collects the exhaled gas and monitors the end-tidal carbon dioxide. After the signal is collected for 0.6 to 1 respiratory cycle, the controller restores the air supply flow of the fan and returns to S2 Proceed to S3 after the current respiration rate and the current capnography cycle are updated.

Optionally, obtaining the current respiratory rate of the patient according to the end-tidal carbon dioxide monitoring signal includes: performing low-pass filtering on the continuously collected end-tidal carbon dioxide monitoring signal Sig0 to obtain a signal Sig1, and eliminating noise introduced by high-flow airflow through filtering, Perform feature extraction on the signal Sig1 to obtain the regular periodic change feature in the signal Sig1, and obtain the patient's current respiration rate according to the periodic change feature; obtain the current end-tidal carbon dioxide monitoring cycle according to the patient's current respiration rate, including: when breathing When the respiratory rate is greater than 60 breaths/minute, the current monitoring cycle of end-tidal carbon dioxide is 20-30 breaths; when the respiratory rate is greater than 30 breaths/minute and less than 60 breaths/minute, the current monitoring cycle of end-tidal carbon dioxide is 15-20 breaths breaths; when the respiratory rate is less than 30 breaths/min, the current monitoring cycle of end-tidal carbon dioxide is 10-15 breaths.

(3) Beneficial effects

The beneficial effects of the present invention are:

The high-flow respiratory humidification therapeutic instrument provided by the present invention is equipped with a gas collection tube and an end-tidal carbon dioxide monitoring module, and the negative pressure active gas sampling unit has an inhalation function, which can collect the gas in the nasal oxygen tube to monitor the end-tidal carbon dioxide Monitoring in the module provides a structural basis for continuous monitoring of end-tidal carbon dioxide to obtain end-tidal carbon dioxide monitoring signals, and provides a structural basis for the collection of exhaled gas when the controller stops the fan supply flow to provide a structural basis for end-tidal carbon dioxide monitoring; through Both the fan and the end-tidal carbon dioxide monitoring module are communicated with the controller, and the controller can control the fan to reduce or stop the air supply flow of the fan at the end of a breath according to the end-tidal carbon dioxide monitoring curve, so that the end-tidal carbon dioxide monitoring module Collect the exhaled gas and monitor the end-tidal carbon dioxide. After the monitoring is over, the controller restores the air supply flow of the fan; by connecting the electronic control valve and the end-tidal carbon dioxide monitoring module with the controller, it can provide synchronous high-flow oxygen for breathing (that is, high-flow oxygen supply only in the inhalation phase) provides a structural basis, which can realize high-flow oxygen supply only in the inhalation process, and the inhalation time only accounts for about 1/3, so the high-flow oxygen supply time is only 1/3. Accounting for 1/3 of the overall time, it can reduce oxygen consumption by 60-70%, and ensure the supply of high-flow oxygen during the inhalation process. It can be seen that the high-flow respiratory humidification therapeutic apparatus provided by the present invention can accurately monitor end-tidal carbon dioxide and reduce oxygen consumption.

Description of drawings

The invention is described with the aid of the following figures:

FIG. 1 is a schematic structural view of a high-flow respiratory humidification therapeutic apparatus according to Embodiment 1 of the present invention, wherein the dotted lines represent communication connections;

2 is a schematic diagram of the first layout of the nasal oxygen tube according to Embodiment 1 of the present invention;

3 is a schematic diagram of a second layout structure of a nasal oxygen tube according to Embodiment 1 of the present invention;

4 is a schematic diagram of the layout structure of the nasal oxygen tube according to Embodiment 2 of the present invention;

Fig. 5 is a schematic flowchart of a method for using the high-flow respiratory humidification therapeutic apparatus according to Embodiment 3 of the present invention.

[Description of Reference Signs]

11: Air intake port; 12: Oxygen intake port; 13: Electric control valve;

2: Air-oxygen mixing tank;

3: fan;

4: nasal oxygen tube; 41: main body; 42: first air outlet; 43: second air outlet; 44: air guide hole;

52: gas collection tube; 53: end-tidal carbon dioxide monitoring module;

6: Controller;

7: Air intake channel;

81: humidification tank; 82: heating module;

91: heating tube; 92: connecting air guide tube.

Detailed ways

In order to better explain the present invention and facilitate understanding, the present invention will be described in detail below through specific embodiments in conjunction with the accompanying drawings.

Example 1

As shown in Figures 1 and 2, the present invention provides a high-flow respiratory humidification treatment instrument, which includes an air-oxygen mixing tank 2, a fan 3, a nasal oxygen tube 4, an end-tidal carbon dioxide monitoring module 53, a gas collection tube 52 and Controller 6; the air inlet of the air-oxygen mixing tank 2 is communicated with the air inlet 11 and the oxygen inlet 12 respectively, and the gas outlet of the air-oxygen mixing tank 2 is communicated with the nasal oxygen tube 4 through the fan 3, and the oxygen inlet 12 is provided with an electric control valve 13 for adjusting the oxygen flow rate; the end-tidal carbon dioxide monitoring module 53 has a built-in negative pressure active gas sampling unit, and the negative pressure active gas sampling unit communicates with the nasal oxygen tube 4 through the gas collection tube 52; the electric control valve 13. Both the fan 3 and the end-tidal carbon dioxide monitoring module 53 are connected to the controller 6 through communication.

In the high-flow respiratory humidification therapy device set up in this way, by setting the gas collection tube 52 and the end-tidal carbon dioxide monitoring module 53, the negative pressure active gas sampling unit has an inhalation function, and can collect the gas in the nasal oxygen tube 4 to the exhalation. Monitoring in the end-tidal carbon dioxide monitoring module 53 provides a structural basis for continuous monitoring of end-tidal carbon dioxide to obtain end-tidal carbon dioxide monitoring signals, and collects the exhaled gas when the controller 6 stops the air supply flow of the fan 3 to monitor the end-tidal carbon dioxide The monitoring provides a structural basis; by connecting the fan 3 and the end-tidal carbon dioxide monitoring module 53 to the controller 6, the controller 6 can control the fan 3 to reduce or stop at the end of a breath according to the end-tidal carbon dioxide monitoring curve. The air supply flow rate of the fan 3, so that the end-tidal carbon dioxide monitoring module 53 collects the exhaled gas and monitors the end-tidal carbon dioxide. After the monitoring is completed, the controller 6 restores the air supply flow rate of the fan 3; The monitoring modules 53 are all communicated with the controller 6, providing a structural basis for breathing synchronous high-flow oxygen supply (that is, high-flow oxygen supply only during the inhalation phase), and can realize high-flow oxygen supply only during the inhalation process, while The inhalation time only accounts for about 1/3, so the high-flow oxygen supply time only accounts for 1/3 of the overall time, which can reduce oxygen consumption by 60-70%, and ensure the high-flow oxygen supply during the inhalation process. It can be seen that the high-flow respiratory humidification therapeutic apparatus provided by the present invention can accurately monitor end-tidal carbon dioxide and reduce oxygen consumption.

As shown in Figure 2, preferably, the nasal oxygen tube 4 includes a main body 41, a tubular air guide hole 44, and a tubular first air outlet 42 and a tubular second air outlet 43 respectively corresponding to the left and right nostrils of the human body; the air guide 44, the first air outlet Air hole 42 and second air outlet hole 43 are all communicated with main body 41, and main body 41 is also provided with air intake hole, fan 3 supplies air to nasal oxygen tube 4 through air intake hole, main body 41 communicates with gas collection pipe 52 through air guide hole 44.

Specifically, in this embodiment, the main body 41 is tubular, and the first air outlet 42 and the second air outlet 43 are both arranged on the first side of the main body 41, and the first air outlet 42 and the second air outlet 43 are connected with each other. The main body 41 communicates with the main body 41 , and the air guide hole 44 is provided at one end of the main body 41 , and the air guide hole 44 communicates with the main body 41 .

Optionally, the air guide hole 44 can also have other layouts on the nasal oxygen tube 4 , for example, the air guide hole 44 is arranged on the second side of the main body 41 (as shown in FIG. 3 ). Optionally, the air guide hole 44 is disposed on the first air outlet hole 42 , and the air guide hole 44 communicates with the first air outlet hole 42 .

Preferably, as shown in Figure 1, the high-flow respiratory humidification therapeutic instrument also includes an air intake channel 7, a humidification tank 81, a heating module 82, a heating tube 91 and a connecting airway 92; the air outlet of the air-oxygen mixing tank 2 passes through The fan 3 is connected with the air inlet of the air intake channel 7, the air outlet of the air intake channel 7 is connected with the air inlet of the humidification tank 81, the air outlet of the humidification tank 81 is connected with the air inlet of the heating tube 91, and the heating tube The air outlet of 91 communicates with the air inlet connected to the air guide tube 92, the air outlet connected to the air guide tube 92 communicates with the nasal oxygen tube 4 through the air intake hole, and the heating module 82 is used to heat the pure water in the humidification tank 81 to The water is evaporated; both the heating module 82 and the heating pipe 91 are connected with the controller 6 in communication. In this way, under the action of the fan 3, the air-oxygen mixture sucked from the air-oxygen mixing tank 2 enters the humidification tank 81 through the air intake channel 7, and the air-oxygen mixed gas flow blown into the humidification tank 81 will carry the evaporation in the humidification tank 81. Moisture enters the heating tube 91, and the air-oxygen mixed flow enters the nasal oxygen tube 4 through the heating tube 91 and the air guide tube 92. The nasal oxygen tube 4 is placed under the nostril, and the humidified gas is introduced into the nostril; by connecting the heating module 82 and the heating tube 91 are all communicated with the controller 6, and the humidity and temperature of the air-oxygen mixture can be controlled by the controller 6.

Preferably, the sampling flow rate of the negative pressure active gas sampling unit is 100mL/min-250mL/min, the inner diameter of the gas collection tube 52 is 0.8-2mm, and the length of the gas collection tube 52 is less than 1.5m. With such setting, the monitoring real-time performance of the end-tidal carbon dioxide monitoring module 53 is improved, and the monitoring time delay is less than 1 second. Further preferably, the sampling flow rate of the negative pressure active gas sampling unit is 150mL/min-250mL/min, the inner diameter of the gas collection tube 52 is 0.8-1.5mm, and the length of the gas collection tube 52 is less than 1m. With such setting, the monitoring real-time performance of the end-tidal carbon dioxide monitoring module 53 is further improved, and the monitoring time delay is less than 0.5s.

Preferably, the starting process time and the stopping process time of the fan 3 are both less than 0.5s. In this way, the fan 3 supports quick start and stop functions, which is beneficial to the real-time monitoring of the end-tidal carbon dioxide monitoring module 53 .

Example 2

The main difference between this embodiment and embodiment 1 is:

As shown in Figure 4, the nasal oxygen tube 4 includes a main body 41, a tubular air guide hole 44, and a tubular first air outlet 42 and a tubular second air outlet 43 respectively corresponding to the left and right nostrils of the human body; the first air outlet 42 and the second air outlet 43 are all communicated with the main body 41, the main body 41 is also provided with an air intake hole, the blower fan 3 supplies air to the nasal oxygen tube 4 through the air intake hole, the air guide hole 44 is arranged side by side with the first air outlet hole 42, and the inlet of the air guide hole 44 The air port and the first air outlet hole 42 are used to extend into the nostrils of the human body, and the air outlet of the air guide hole 44 communicates with the gas collection tube 52 .

The rest of the similarities with Embodiment 1 will not be repeated here.

Example 3

This embodiment provides a method for using the high-flow respiratory humidification therapeutic instrument as described in Embodiment 1 or Embodiment 2, including the following steps:

S1. During the process of high-flow respiratory humidification therapy for patients by the high-flow respiratory humidification therapeutic instrument, the end-tidal carbon dioxide monitoring module continuously samples and monitors the end-tidal carbon dioxide concentration to obtain the end-tidal carbon dioxide monitoring signal.

Specifically, in S1, the starting moment for the end-tidal carbon dioxide monitoring module to continuously monitor the end-tidal carbon dioxide may be when the high-flow respiratory humidification treatment device starts to perform high-flow respiratory humidification treatment on the patient.

S2. Obtain the current respiratory rate of the patient according to the end-tidal carbon dioxide monitoring signal, and obtain the current monitoring period of the end-tidal carbon dioxide according to the respiratory rate.

It should be noted that although the end-tidal carbon dioxide monitoring module cannot accurately monitor the end-tidal carbon dioxide concentration during the high-flow respiratory humidification treatment, the end-tidal carbon dioxide monitoring module can continuously sample and monitor the end-tidal carbon dioxide concentration to obtain the The periodic change law of end-tidal carbon dioxide can reflect the current respiratory rate of the patient and the current monitoring cycle of end-tidal carbon dioxide.

Preferably, the current respiratory rate of the patient is obtained according to the end-tidal carbon dioxide monitoring signal, which includes: performing low-pass filtering on the continuously collected end-tidal carbon dioxide monitoring signal Sig0 to obtain the signal Sig1, and eliminating the noise introduced by the high-flow airflow through filtering. The feature extraction of the signal Sig1 is carried out to obtain the regular periodic change feature in the signal Sig1, and the patient's current respiratory rate is obtained according to the periodic change feature; according to the patient's current respiratory rate, the current end-tidal carbon dioxide monitoring period is obtained, including: when the respiratory rate When it is greater than 60 breaths/minute, the current monitoring cycle of end-tidal carbon dioxide is 20-30 breaths; when the respiratory rate is greater than 30 breaths/minute and less than 60 breaths/minute, the current monitoring cycle of end-tidal carbon dioxide is 15-20 breaths Respiration; when the respiration rate is less than 30 breaths/minute, the current monitoring cycle for end-tidal carbon dioxide is 10-15 breaths. The above-mentioned corresponding relationship between the patient's respiratory rate and the end-tidal carbon dioxide monitoring cycle was obtained by the inventor after a large number of clinical trials and statistical exploration. In this way, end-tidal carbon dioxide can be accurately monitored in real time while high-flow respiratory therapy is ensured.

S3. Starting from the moment when the current respiration rate is obtained, according to the current respiration rate, the controller reduces or stops the gas flow at the oxygen inlet end through the electric control valve at the end of each breath inhalation, and before the inhalation of each breath begins The controller restores the air supply flow at the oxygen intake end through the electronic control valve; starting from the moment when the current breathing rate is obtained, according to the current breathing rate, when the number of breathing reaches the current end-tidal carbon dioxide monitoring cycle, it is controlled at the end of the next breath. The controller reduces or stops the air supply flow of the fan, and the end-tidal carbon dioxide monitoring module collects the exhaled gas and monitors the end-tidal carbon dioxide. After the signal is collected for 0.6 to 1 respiratory cycle, the controller restores the air supply flow of the fan and returns to S2 Proceed to S3 after the current respiration rate and the current capnography cycle are updated.

Specifically, in the method for using the high-flow respiratory humidification therapeutic apparatus provided by the present invention, the first determination of the current respiratory rate and the current end-tidal carbon dioxide monitoring cycle is based on the end-tidal carbon dioxide monitoring module from the high-flow respiratory humidification therapeutic apparatus. The end-tidal carbon dioxide monitoring signal obtained by continuously monitoring the end-tidal carbon dioxide concentration for 0.5min to 1min was started when the patient was treated.

The method for using the high-flow respiratory humidification therapy device proposed by the present invention can monitor end-tidal carbon dioxide in real time and accurately during high-flow respiratory therapy while ensuring high-flow respiratory therapy, and can reduce high-flow respiratory humidity. Oxygen consumption of the chemotherapy device.

It should be understood that the above description of the specific embodiments of the present invention is only to illustrate the technical route and characteristics of the present invention, and its purpose is to allow those skilled in the art to understand the content of the present invention and implement it accordingly, but the present invention It is not limited to the specific embodiments described above. All changes or modifications made within the scope of the claims of the present invention shall fall within the protection scope of the present invention.

Claims (9)

1. A high-flow respiratory humidification therapeutic instrument, characterized in that, Including air-oxygen mixing tank (2), fan (3), nasal oxygen tube (4), end-tidal carbon dioxide monitoring module (53), gas collection tube (52) and controller (6); air-oxygen mixing tank (2 ) is communicated with the air inlet port (11) and the oxygen inlet port (12) respectively, the air outlet of the air-oxygen mixing tank (2) is communicated with the nasal oxygen tube (4) through the blower fan (3), and the oxygen inlet The gas end (12) is provided with an electric control valve (13) for adjusting the oxygen flow rate; the end-tidal carbon dioxide monitoring module (53) has a built-in negative pressure active gas sampling unit, and the negative pressure active gas sampling unit passes through the gas collection tube (52) It communicates with the nasal oxygen tube (4); the electric control valve (13), the blower fan (3) and the end-tidal carbon dioxide monitoring module (53) are all communicatively connected with the controller (6). 2. The high-flow respiratory humidification therapeutic instrument according to claim 1, characterized in that, The nasal oxygen tube (4) comprises a main body (41), a tubular air guide hole (44), and a tubular first air outlet (42) and a tubular second air outlet (43) respectively corresponding to the left and right nostrils of the human body; the air guide hole (44), The first air outlet (42) and the second air outlet (43) are all communicated with the main body (41), and the main body (41) is also provided with an air inlet, and the blower fan (3) flows through the air inlet to the nasal oxygen tube (4) Air supply, the main body (41) communicates with the gas collection pipe (52) through the air guide hole (44). 3. The high-flow respiratory humidification therapeutic instrument according to claim 2, characterized in that, The main body (41) is tubular, the first air outlet (42) and the second air outlet (43) are all arranged on the first side of the main body (41), and the first air outlet (42) and the second air outlet (43) ) are all communicated with the main body (41), the air guide hole (44) is arranged at one end of the main body (41), and the air guide hole (44) communicates with the main body (41). 4. The high-flow respiratory humidification therapeutic instrument according to claim 1, characterized in that, The high-flow respiratory humidification therapeutic instrument also includes an air intake channel (7), a humidification tank (81), a heating module (82), a heating tube (91) and a connecting airway tube (92); the air-oxygen mixing tank (2) The air outlet communicates with the air inlet of the air intake channel (7) through the fan (3), the air outlet of the air intake channel (7) communicates with the air inlet of the humidification tank (81), and the outlet of the humidification tank (81) Air port is communicated with the air inlet of heating tube (91), and the gas outlet of heating tube (91) is communicated with the air inlet of connecting air guide tube (92), and the air outlet of connecting air guide tube (92) passes air inlet and nasal oxygen. The pipe (4) is connected, and the heating module (82) is used to heat the pure water in the humidification tank (81) to evaporate the water; both the heating module (82) and the heating pipe (91) communicate with the controller (6) connect. 5. The high-flow respiratory humidification therapeutic instrument according to claim 1, characterized in that, The sampling flow rate of the negative pressure active gas sampling unit is 100mL/min-250mL/min, the inner diameter of the gas collection tube (52) is 0.8-2mm, and the length of the gas collection tube (52) is less than 1.5m. 6. The high-flow respiratory humidification therapeutic instrument according to claim 5, characterized in that, The sampling flow rate of the negative pressure active gas sampling unit is 150mL/min-250mL/min, and the inner diameter of the gas collection tube (52) is 0.8-1.5mm. 7. The high-flow respiratory humidification therapeutic instrument according to claim 1, characterized in that, The nasal oxygen tube (4) comprises a main body (41), a tubular air guide hole (44), and a tubular first air outlet (42) and a tubular second air outlet (43) respectively corresponding to the left and right nostrils of the human body; the first air outlet (42 ) and the second air outlet (43) are all communicated with the main body (41), and the main body (41) is also provided with an air inlet, and the blower fan (3) supplies air to the nasal oxygen tube (4) through the air inlet, and the air guide hole (44 ) and the first air outlet (42) are arranged side by side, and the air inlet of the air guide hole (44) is used to stretch into the nostril of the human body together with the first air outlet (42), and the air outlet of the air guide hole (44) is connected with the gas The collection pipe (52) is connected. 8. A method of using the high-flow respiratory humidification therapeutic apparatus according to any one of claims 1 to 7, characterized in that it comprises the following steps: S1. During the process of high-flow respiratory humidification treatment for patients by the high-flow respiratory humidification therapeutic instrument, the end-tidal carbon dioxide monitoring module continuously samples and monitors the end-tidal carbon dioxide concentration to obtain the end-tidal carbon dioxide monitoring signal; S2. Obtain the current respiration rate of the patient according to the end-tidal carbon dioxide monitoring signal, and obtain the current end-tidal carbon dioxide monitoring period according to the respiration rate; S3. Starting from the moment when the current respiration rate is obtained, according to the current respiration rate, the controller reduces or stops the gas flow at the oxygen inlet end through the electric control valve at the end of each breath inhalation, and before the inhalation of each breath begins The controller restores the air supply flow at the oxygen intake end through the electronic control valve; starting from the moment when the current breathing rate is obtained, according to the current breathing rate, when the number of breathing reaches the current end-tidal carbon dioxide monitoring cycle, it is controlled at the end of the next breath. The controller reduces or stops the air supply flow of the fan, and the end-tidal carbon dioxide monitoring module collects the exhaled gas and monitors the end-tidal carbon dioxide. After the signal is collected for 0.6 to 1 respiratory cycle, the controller restores the air supply flow of the fan and returns to S2 Proceed to S3 after the current respiration rate and the current capnography cycle are updated. 9. The method for using the high-flow respiratory humidification therapeutic instrument according to claim 8, characterized in that, According to the end-tidal carbon dioxide monitoring signal, the current respiratory rate of the patient is obtained, including: performing low-pass filtering on the continuously collected end-tidal carbon dioxide monitoring signal Sig0 to obtain the signal Sig1, eliminating the noise introduced by the high-flow airflow through filtering, and processing the signal Sig1 Feature extraction, obtaining the regular periodic change feature in the signal Sig1, and obtaining the patient's current respiration rate according to the periodic change feature; According to the patient's current breathing rate, the current monitoring cycle of end-tidal carbon dioxide is obtained, including: when the breathing rate is greater than 60 times/min, the current monitoring cycle of end-tidal carbon dioxide is 20-30 breaths, and when the breathing rate is greater than 30 breaths When the breathing rate is less than 60 breaths/minute, the current monitoring cycle of end-tidal carbon dioxide is 15-20 breaths; when the respiratory rate is less than 30 breaths/minute, the current monitoring cycle of end-tidal carbon dioxide is 10-15 breaths.

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