CN1162399A - Tea of Japanese yew and preparation thereof - Google Patents

Tea of Japanese yew and preparation thereof Download PDF

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Publication number
CN1162399A
CN1162399A CN 97102754 CN97102754A CN1162399A CN 1162399 A CN1162399 A CN 1162399A CN 97102754 CN97102754 CN 97102754 CN 97102754 A CN97102754 A CN 97102754A CN 1162399 A CN1162399 A CN 1162399A
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China
Prior art keywords
leaf
stem
tea
cinnamic acid
ethanol
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Pending
Application number
CN 97102754
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Chinese (zh)
Inventor
刘培林
闻殿墀
杨春田
谢虎峰
Original Assignee
朱德纪
张浩然
刘培林
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Application filed by 朱德纪, 张浩然, 刘培林 filed Critical 朱德纪
Priority to CN 97102754 priority Critical patent/CN1162399A/en
Publication of CN1162399A publication Critical patent/CN1162399A/en
Pending legal-status Critical Current

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Abstract

A yew tea is prepared from young stem leaves of cuttage yew through washing, grinding, degreasing, removing saccharide in water, esterifying surficial water, immersing in alcohol, esterifying, drying in sun, breaking and proportioning, and features that it contains water-soluble taxusol so that it has health-care function to prevent cold and cancer and cure diarrhea.

Description

Tea of Japanese yew and preparation method thereof
The present invention relates to a kind of health promoting beverage, tea of Japanese yew and preparation method thereof.
Health promoting beverage is more at present, but does not find as yet as the health promoting beverage of raw material with Ramulus et folium taxi cuspidatae.
Ramulus et folium taxi cuspidatae (Taxus cuspidata S.et z.) has another name called Ramulus et folium taxi cuspidatae, Chi Baisong, contains anticancer effective component paclitaxel (Taxol)." book on Chinese herbal medicine pushes away old " claims its diuresis, stimulates the menstrual flow, controls nephropathy, diabetes.
The U.S., Korea S and Japan extract more than 20 kind of taxanes diterpene-kind compound respectively from Ramulus et folium taxi cuspidatae, Pacific Ocean Ramulus et folium taxi cuspidatae.From yewtree, isolate paclitaxel (Taxol) seventies (Wani) etc., and proof there is the obvious suppression effect to cancerous cell.The eighties, the U.S. began the secondary clinical test of paclitaxel, began three grades of clinical trials the nineties, and in December, the 92 official approval paclitaxel new anti-cancer drug for the treatment advanced ovarian cancer.
China some unit nineties has been engaged in the research that paclitaxel extracts, and minority unit extracts pure product of paclitaxel, has had commercial value, is used to sell medicine, and rarely seen have the purple element of institute of Materia Medica,Chinese Academy of Medical Sciences development by 135~250mg/m 2The treatment patient obtains alleviation.
But Ramulus et folium taxi cuspidatae is used for the research of medicated tea, still is not reported.Some people once had this idea, but because paclitaxel is water insoluble, and not anti-greater than the temperature more than 40 ℃, the result fails because of unresolved this type of problem.
The objective of the invention is to solve the water-soluble technical problem of paclitaxel, it is combined with water, be convenient to absorption of human body, and the not anti-problem greater than temperature more than 40 ℃ of paclitaxel.Make tea of Japanese yew and manufacture method thereof that people are convenient to drink, make paclitaxel offer society as a kind of beverage.Also solving simultaneously and proposing paclitaxel at present mainly is that exploitation is extracted from bark, has damaged resource, and tea of Japanese yew is to utilize to extract in the young stem and leaf of cottage propagation, has protected precious resources.
Major technique content of the present invention is, this tea of Japanese yew is to be that raw material is after processing and be equipped with the tea core and make with Ramulus et folium taxi cuspidatae children young stem and leaf.
The technological process of its production is:
Cuttage Ramulus et folium taxi cuspidatae stem and leaf → clean → roll → defat → water maltosemalt sugar → dry → alcohol leaching → esterification → dry → pulverize → join tea.
At first get the young stem and leaf of Ramulus et folium taxi cuspidatae cottage propagation, it is removed foreign material, clean up; After roll, the young stem and leaf that cleans up is ground broken leaf epidermis, make resinae be easy to stripping; Back defat is 1%Al with concentration 2(SO 4) 3Handle, soak Ramulus et folium taxi cuspidatae stem and leaf 24 hours (with Al through rolling 2(SO 4) 3Flooding the Ramulus et folium taxi cuspidatae stem and leaf is advisable); Residual Al is totally removed in back drip washing 2(SO 4) 3, pull stem and leaf out; Back water maltosemalt sugar, the stem and leaf that is soaked in water was pulled out after 12 hours; Dry, the method for employing natural drying or drying is removed the excessive moisture of stem and leaf, makes its moisture content reach 20~40%; Back alcohol leaching, with stem and leaf weight 50%, concentration is that the sealing of 95% ethanol is soaked vexed 30~40 days, and often vibrate or stir, be i.e. stem and leaf weight: ethanol weight=1: 0.5; Back esterification is carried out esterification treatment with cinnamic acid, is ethanol by using the every 1g of ethanol to add cinnamic acid 0.057g: cinnamic acid=1: 0.057 weight adds cinnamic acid makes it become cinnamic acid fat; After dry; Pulverize back adding tea core and promptly get tea of Japanese yew, its proportioning is a yew leaf: tea core=1: 1~2.
Technique effect of the present invention is, makes the paclitaxel water soluble that contains in the stem and leaf after the processing such as the young stem and leaf process of Ramulus et folium taxi cuspidatae rolls, defat, water maltosemalt sugar, alcohol leaching, esterification.Therefore can drink for people as tea, thereby reach function of health care.Its principle is that paclitaxel loses diformazan ammonia and is decomposed into cinnamate (You Kang such as waits at work, terpenoid chemistry, Beijing higher education publishing house, 1984); But with the cis cinnamic acid is main component taxol biosynthesis (Fang Weishuo: the chemical research of paclitaxel, the 29th the 5th phase of volume of Chinese medicine magazine 1994); Paclitaxel tool height lipotropy (work such as Qiu Deyou anticarcinogen paclitaxel, publishing house of Beijing University, 1996); Cinnamic acid fat and 97% water form azeotropic mixture, and boiling point 99.93% is the same with ethanol formation azeotropic mixture as water, can be absorption of human body (Cheng Nenglin: solvent handbook, Chemical Industry Press).After ungrease treatment, resin, tannin reduce 85%; No matter hot dipping of tea of Japanese yew, warm macerating or merceration, its millet paste all can be seen and contain the paclitaxel composition through the thin layer chromatography inspection.The millet paste taste is aromatic tasty and refreshing, suitable drinking.The effect that this tea set has preventing cold, antidiarrheal, separates spasm, prevents curing cancers after many people drink.For postoperative cancer patient, drinking tea of Japanese yew not only has mitigation to disease, and expense is much lower than chemotherapy and Drug therapy simultaneously.
Realize embodiments of the invention:
Get Ramulus et folium taxi cuspidatae children stem and leaf 1000g, concentration is 95% ethanol 500ml, cinnamic acid 285g, adds tea core 1000g, can make tea of Japanese yew 2000g through above-mentioned process.

Claims (2)

1, tea of Japanese yew is characterized in that, this tea is to be that raw material is after processing and be equipped with the tea core and make with Ramulus et folium taxi cuspidatae children young stem and leaf.
2, the preparation method of the described tea of Japanese yew of claim 1 is, at first gets Ramulus et folium taxi cuspidatae children young stem and leaf, and it is removed foreign material, cleans up; After roll, the Ramulus et folium taxi cuspidatae that cleans up children stem and leaf is ground broken leaf epidermis; Back defat is 1%Al with concentration 2(SO 4) 3The stem and leaf of immersion through rolling 24 hours, Al 2(SO 4) 3The consumption of solution is advisable to flood stem and leaf, and residual Al is totally removed in back drip washing 2(SO 4) 3, pull stem and leaf out; Back water maltosemalt sugar, the stem and leaf that is soaked in water was pulled out after 12 hours; Dry, the method for employing natural drying or drying is removed the excessive moisture of stem and leaf, makes its moisture content reach 20~40%; Back alcohol leaching, with stem and leaf weight 50%, concentration is that the sealing of 95% ethanol is soaked vexed 30~40 days, and often vibrate or stir, be i.e. stem and leaf weight: ethanol weight=1: 0.5; Back esterification is carried out esterification treatment with cinnamic acid, and the consumption of cinnamic acid is an ethanol by using the every 1g of ethanol to add cinnamic acid 0.057g: cinnamic acid=1: 0.057 (weight ratio) adds cinnamic acid; After dry; Add the tea core again and promptly get tea of Japanese yew, its weight proportion is a yew leaf: tea core=1: 1~2.
CN 97102754 1997-04-11 1997-04-11 Tea of Japanese yew and preparation thereof Pending CN1162399A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 97102754 CN1162399A (en) 1997-04-11 1997-04-11 Tea of Japanese yew and preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 97102754 CN1162399A (en) 1997-04-11 1997-04-11 Tea of Japanese yew and preparation thereof

Publications (1)

Publication Number Publication Date
CN1162399A true CN1162399A (en) 1997-10-22

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CN 97102754 Pending CN1162399A (en) 1997-04-11 1997-04-11 Tea of Japanese yew and preparation thereof

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CN (1) CN1162399A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101983575A (en) * 2010-11-26 2011-03-09 江西荣通农业发展有限公司 Yew leaf tea and compound tea containing same as well as preparation methods thereof
CN103719485A (en) * 2013-12-04 2014-04-16 黎川县东鑫实业有限公司 Compound yew tea effervescent tablet and preparation process thereof
CN103815073A (en) * 2014-02-17 2014-05-28 薛保国 Chinese yew tea and preparation method thereof
CN104605071A (en) * 2015-01-14 2015-05-13 湄潭银柜山茶业有限公司 Process for making taxus chinensis leaf health care tea
WO2015135090A1 (en) * 2014-03-10 2015-09-17 赵迪 Yew health care tea and preparation method therefor

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101983575A (en) * 2010-11-26 2011-03-09 江西荣通农业发展有限公司 Yew leaf tea and compound tea containing same as well as preparation methods thereof
CN103719485A (en) * 2013-12-04 2014-04-16 黎川县东鑫实业有限公司 Compound yew tea effervescent tablet and preparation process thereof
CN103815073A (en) * 2014-02-17 2014-05-28 薛保国 Chinese yew tea and preparation method thereof
WO2015135090A1 (en) * 2014-03-10 2015-09-17 赵迪 Yew health care tea and preparation method therefor
CN104605071A (en) * 2015-01-14 2015-05-13 湄潭银柜山茶业有限公司 Process for making taxus chinensis leaf health care tea

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