CN116211989A - A traditional Chinese medicinal bath liquid for rehabilitation treatment of childbirth brachial plexus injury - Google Patents

A traditional Chinese medicinal bath liquid for rehabilitation treatment of childbirth brachial plexus injury Download PDF

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CN116211989A
CN116211989A CN202310502709.0A CN202310502709A CN116211989A CN 116211989 A CN116211989 A CN 116211989A CN 202310502709 A CN202310502709 A CN 202310502709A CN 116211989 A CN116211989 A CN 116211989A
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traditional chinese
chinese medicine
childbirth
brachial plexus
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李海天
马建强
张曼
付晓虎
吕忠礼
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Beijing Childrens Hospital
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Abstract

本发明提供了一种配合康复治疗分娩性臂丛神经损伤的中药药浴液,属于中药技术领域。本发明的药浴中药由以下重量份的原料组成:当归15‑40份,黄芪15‑30份,五灵脂15‑30份,儿茶1‑7份,千年健10‑30份,木瓜15‑30份,伸筋草10‑30份,桑枝10‑30份,白鲜皮10‑30份,羌活10‑30份,秦艽10‑30份,姜黄10‑30份,佛手5‑20份,郁李仁5‑20份。本药浴中药配合康复治疗分娩性臂丛神经损伤,疗效提高显著,改善了分娩性臂丛神经损伤患儿基础动作、手部功能、协调性和整体功能,无不良反应,使用方便。The invention provides a traditional Chinese medicinal bath liquid for rehabilitation treatment of childbirth brachial plexus injury, which belongs to the technical field of traditional Chinese medicine. The medicated bath Chinese medicine of the present invention is made up of the following raw materials by weight: 15-40 parts of angelica, 15-30 parts of astragalus, 15-30 parts of Wulingzhi, 1-7 parts of catechu, 10-30 parts of Qiannianjian, 15 parts of papaya ‑30 parts, 10‑30 parts of Shenjincao, 10‑30 parts of mulberry branches, 10‑30 parts of white fresh bark, 10‑30 parts of notopterygium, 10‑30 parts of Gentiana, 10‑30 parts of turmeric, 5‑20 parts of bergamot , Yu Liren 5‑20 copies. The medicated bath traditional Chinese medicine combined with rehabilitation treatment of childbirth brachial plexus injury has significantly improved curative effect, improved basic movement, hand function, coordination and overall function of children with childbirth brachial plexus injury, has no adverse reactions, and is convenient to use.

Description

一种配合康复治疗分娩性臂丛神经损伤的中药药浴液A traditional Chinese medicinal bath liquid for rehabilitation treatment of childbirth brachial plexus injury

技术领域technical field

本发明属于中药技术领域,具体的涉及一种配合康复治疗分娩性臂丛神经损伤的中药药浴液,及其组合物和应用。The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicinal bath liquid for rehabilitation and treatment of childbirth brachial plexus injuries, as well as its composition and application.

背景技术Background technique

随着物质生活水平的不断改善,出生时出现巨大儿等情况越来越多;在生产过程中易造成肩难产,以致由于过度牵拉臂丛或锁骨骨折等造成分娩性臂丛神经损伤。分娩性臂丛神经损伤又称产瘫,是由于在分娩过程中多种原因引起的头肩分离作用而发生的臂丛神经牵拉性损伤,临床表现为新生儿患侧上肢不同程度的感觉、运动功能障碍,初期表现为软瘫,继而可出现肌肉萎缩、挛缩,肩关节内收内旋挛缩并可能引起肩关节半脱位和脱位,肘关节屈曲挛缩并可能引起桡骨头后脱位、肘关节后脱位,前臂旋前旋后畸形和手部畸形。各国报道的发病率差异较大,在0.15‰-3‰之间。由于患儿正处于运动发育的关键时期,不及时治疗会影响其运动功能,遗留残疾。目前临床上臂丛神经损伤多采取康复训练、针灸推拿等保守治疗,重者需进行手术治疗,尽管分娩性臂丛神经损伤的疗效已明显提高,但仍有许多患儿遗留有不同程度的功能障碍。因此,进一步提高分娩性臂丛神经损伤的疗效是临床急需解决的问题。With the continuous improvement of material living standards, there are more and more cases of macrosomia at birth; during the production process, it is easy to cause shoulder dystocia, so that childbirth brachial plexus injuries are caused by excessive stretching of the brachial plexus or clavicle fractures. Childbirth brachial plexus injury, also known as obstetrical paralysis, is a tractive injury of the brachial plexus that occurs due to the separation of the head and shoulders caused by various reasons during childbirth. Motor dysfunction, initially manifested as flaccid paralysis, followed by muscle atrophy and contracture, adduction and internal rotation contracture of the shoulder joint may cause shoulder subluxation and dislocation, elbow flexion contracture may cause posterior dislocation of the radial head, posterior elbow joint Dislocation, pronation and supination of the forearm and deformity of the hand. The reported incidence rate varies greatly from country to country, ranging from 0.15‰ to 3‰. Since the child is in a critical period of motor development, if not treated in time, it will affect its motor function and leave disability. At present, conservative treatment of upper brachial plexus injury is usually performed by rehabilitation training, acupuncture and massage, and severe cases require surgical treatment. Although the curative effect of childbirth brachial plexus injury has been significantly improved, many children still have different degrees of dysfunction . Therefore, further improving the curative effect of childbirth brachial plexus injury is a clinical problem that needs to be solved urgently.

中医古籍文献中没有记载“分娩性臂丛神经损伤”,但中医的痿证内涵包括肢体筋脉弛缓,软弱无力,不能随意运动,或伴有肌肉萎缩。《素问痿论》认为“肺主身之皮毛,心主身之血脉,肝主身之筋膜,脾主身之肌肉,肾主身之骨髓。故肺热叶焦,则皮毛虚弱急薄,著则生痿躄也;心气热,则下脉厥而上,上则下脉虚,虚则生脉痿,枢折挈,胫纵而不任地也;肝气热,则胆泄口苦筋膜干,筋膜干则筋急而挛,发为筋痿;脾气热,则胃干而渴,肌肉不仁,发为肉痿;肾气热,则腰脊不举,骨枯而髓减,发为骨痿。”中医经筋的功能主要是连接骨骼,进行各种活动。《素问痿论》:“宗筋主束骨而利机关也”、《素问五藏生成篇》:“诸筋者皆属于节”、《素问痹论》:“痹在于筋,则屈不伸”、《素问长刺节篇》:“病在筋,筋挛节痛,不可以行,名曰筋痹”等。也就是说,经筋主要对关节屈伸和肌肉运动起作用,其证候主要表现在运动功能障碍:如局部或全身肌肉拘急抽搐、强直以及弛缓、瘫痪等。药浴中药在治疗“痿证”“筋伤”上积累大量的经验。根据现代医学中分娩性臂丛神经损伤的病因和临床表现,分娩性臂丛神经损伤可归为“痿证”“筋伤”范畴。病因病机为由于产时外伤造成恶血内留,气滞血瘀,经络不通,痰湿内阻,四肢失于濡养滋养,筋脉失养而发上肢无力,后期久病耗气血,久病及肾等,并且瘀血内阻,经脉不通,痰湿内生,筋骨脉失养,继而出现肌肉萎缩、挛缩,关节不利。本病多虚实夹杂,以肝脾肾为主。There is no record of "parturient brachial plexus injury" in the ancient books of traditional Chinese medicine, but the connotation of atrophy syndrome in traditional Chinese medicine includes relaxation of limbs, weakness, inability to move freely, or accompanied by muscle atrophy. "Suwen impotence theory" believes that "the lung governs the fur of the body, the heart governs the blood of the body, the liver governs the fascia of the body, the spleen governs the muscles of the body, and the kidney governs the bone marrow of the body. Therefore, when the lungs are hot and the leaves are scorched, the fur is weak and thin. If the heart qi is hot, the lower vessels will turn upwards, and the upper ones will cause the lower vessels to become deficient, and if they are deficient, the pulses will become flaccid, the pivots will be folded, and the shin will be vertical and not on the ground; if the liver qi is hot, the gallbladder will be vented and the mouth will be bitter. If the fascia is dry, the fascia is dry, and the tendons are tense and contracted, which is muscle flaccidity; when the temper is hot, the stomach is dry and thirsty, the muscles are not benevolent, and the hair is flaccid; Fat is bone flaccidity." The function of tendons in traditional Chinese medicine is mainly to connect bones and carry out various activities. "Suwen impotence theory": "Zong tendons govern the bones and benefit the organs", "Suwen Wuzang Shengpian": "All tendons belong to joints", "Suwen Bilun": "Blurries lie in tendons, then Bend or not stretch", "Suwen Changci Jiepian": "The disease lies in the tendons, the tendons are cramped and painful, and it is impossible to move, which is called tendon paralysis" and so on. That is to say, the meridians mainly play a role in joint flexion and muscle movement, and its syndromes are mainly manifested in motor dysfunction: such as local or whole body muscle jerk, rigidity, relaxation, and paralysis. Medicinal bath traditional Chinese medicine has accumulated a lot of experience in the treatment of "flareness syndrome" and "muscle injury". According to the etiology and clinical manifestations of childbirth brachial plexus injury in modern medicine, childbirth brachial plexus injury can be classified into the categories of "atrophy syndrome" and "muscle injury". The etiology and pathogenesis are due to trauma during childbirth that causes bad blood to stay in, stagnation of qi and blood stasis, blockage of meridians and collaterals, internal resistance of phlegm and dampness, loss of nourishment and nourishment of the limbs, loss of nourishment of the tendons and arteries, resulting in weakness of the upper limbs, and the consumption of qi and blood due to prolonged illness in the later stage. Long-term illness and kidney, etc., and blood stasis and internal resistance, meridians blocked, phlegm dampness inborn, muscles and arteries lack of nourishment, followed by muscle atrophy, contracture, and joint disadvantages. Primary disease is mostly mixed with deficiency and excess, mainly based on liver, spleen and kidney.

虽然经过康复训练、针灸、按摩等保守康复或手术治疗,许多分娩性臂丛神经损伤患儿恢复仍欠佳,进一步提高分娩性臂丛神经损伤的疗效是临床急需解决的问题。中药治疗“痿证”“筋伤”都有一定优势,药浴中药配合康复治疗分娩性臂丛神经损伤是值得临床探索的方向。Although conservative rehabilitation or surgical treatment such as rehabilitation training, acupuncture, massage, etc., many children with childbirth brachial plexus injury still do not recover well. Further improving the curative effect of childbirth brachial plexus injury is an urgent clinical problem to be solved. Traditional Chinese medicine has certain advantages in the treatment of "atrophy syndrome" and "muscle injury". The combination of medicinal bath with traditional Chinese medicine and rehabilitation in the treatment of childbirth brachial plexus injury is a direction worthy of clinical exploration.

发明内容Contents of the invention

针对以上内容,本发明的目的是提供一种配合康复治疗分娩性臂丛神经损伤的药浴中药及其应用,本发明药浴中药具有疗效好,使用方便,无副作用等优势。In view of the above, the object of the present invention is to provide a medicinal bath traditional Chinese medicine for rehabilitation and treatment of childbirth brachial plexus injury and its application. The medicinal bath traditional Chinese medicine of the present invention has the advantages of good curative effect, convenient use, and no side effects.

为了实现上述目的,本发明提供以下技术方案:In order to achieve the above object, the present invention provides the following technical solutions:

本发明提供了一种配合康复治疗分娩性臂丛神经损伤的药浴中药,由以下重量份的原料组成:当归15-40份,黄芪15-30份,五灵脂15-30份,儿茶1-7份,千年健10-30份,木瓜15-30份,伸筋草10-30份,桑枝10-30份,白鲜皮10-30份,羌活10-30份,秦艽10-30份,姜黄10-30份,佛手5-20份,郁李仁5-20份。The invention provides a medicinal bath traditional Chinese medicine for rehabilitation treatment of childbirth brachial plexus injury. 1-7 parts, 10-30 parts of Qiannianjian, 15-30 parts of papaya, 10-30 parts of Shenjincao, 10-30 parts of mulberry branch, 10-30 parts of white fresh skin, 10-30 parts of Notopterygium, 10- 30 parts, turmeric 10-30 parts, bergamot 5-20 parts, Yu Liren 5-20 parts.

优选地,所述药浴中药由以下重量份的原料组成:当归15-30份,黄芪15-25份,五灵脂15-20份,儿茶1-5份,千年健15-20份,木瓜15-20份,伸筋草15-20份,桑枝15-20份,白鲜皮15-20份,羌活15-20份,秦艽15-20份,姜黄15-20份,佛手5-15份,郁李仁5-15份。Preferably, the medicinal bath medicine is composed of the following raw materials in parts by weight: 15-30 parts of angelica, 15-25 parts of astragalus, 15-20 parts of Wulingzhi, 1-5 parts of catechu, 15-20 parts of Qiannianjian, 15-20 parts of papaya, 15-20 parts of Shenjincao, 15-20 parts of mulberry branch, 15-20 parts of white fresh skin, 15-20 parts of notopterygium, 15-20 parts of Gentiana, 15-20 parts of turmeric, 5- 15 copies, Yu Liren 5-15 copies.

优选地,所述药浴中药由以下重量份的原料组成:当归20份,黄芪18份,五灵脂18份,儿茶3份,千年健15份,木瓜18份,伸筋草15份,桑枝15份,白鲜皮15份,羌活15份,秦艽15份,姜黄15份,佛手10份,郁李仁6份。Preferably, the medicated bath medicine consists of the following raw materials in parts by weight: 20 parts of angelica, 18 parts of astragalus, 18 parts of Wulingzhi, 3 parts of catechu, 15 parts of Qiannianjian, 18 parts of papaya, 15 parts of Shenjincao, 15 parts of mulberry branch, 15 parts of white fresh skin, 15 parts of Qianghuo, 15 parts of Gentiana chinensis, 15 parts of turmeric, 10 parts of bergamot, and 6 parts of Yu Liren.

本发明组合物中,当归,甘、辛,温,入肝、心、脾经,具有活血补血,调经止痛的功效。用于血虚萎黄,眩晕心悸,月经不调,经闭痛经,虚寒腹痛,风湿痹痛,跌扑损伤,痈疽疮疡,肠燥便秘。In the composition of the present invention, angelica, sweet, pungent, warm, enters the liver, heart and spleen meridian, has the effects of promoting blood circulation, nourishing blood, regulating menstruation and relieving pain. For blood deficiency and yellow complexion, dizziness and palpitations, irregular menstruation, amenorrhea dysmenorrhea, abdominal pain due to deficiency and cold, rheumatism arthralgia, injury from falls, carbuncle sores, intestinal dryness and constipation.

本发明组合物中,黄芪, 甘温,归脾、肺两经,具有补气固表、敛疮生肌、利水消肿、托毒、排脓的功效。用于气虚乏力、食少便溏,中气下陷,久泻脱肛,自汗盗汗,血虚萎黄,阴疽漫肿,气虚水肿,内热消渴 In the composition of the present invention, Astragalus membranaceus, sweet and warm, returns to the spleen and lung meridians, and has the effects of invigorating qi and strengthening the exterior, suppressing sores and promoting granulation, diuresis for reducing swelling, supporting toxins, and evacuating pus. For qi deficiency and fatigue, lack of food and loose stools, depression of middle qi, chronic diarrhea and prolapse of the anus, spontaneous sweating and night sweats, blood deficiency and chlorosis, diffuse swelling of genital gangrene, edema due to qi deficiency, internal heat and quenching thirst

本发明组合物中,五灵脂,甘温,苦、辛,入肝经。有活血散瘀,止痛的功效。用于胸腹疼痛,经行腹痛,产后瘀滞腹痛等症;瘀滞出血病证;治跌打损伤,虫、蛇咬伤。In the composition of the present invention, Wulingzhi, sweet and warm, bitter and pungent, enters the liver meridian. It has the effects of promoting blood circulation and removing blood stasis, and relieving pain. For chest and abdomen pain, abdominal pain during menstruation, postpartum stasis and abdominal pain embolism; stasis and bleeding syndrome; treatment of bruises, insect and snake bites.

本发明组合物中,儿茶,苦、涩,微寒,归肺、心经。功效活血止痛,止血生肌,收湿敛疮,清肺化痰。用于跌扑伤痛,外伤出血,吐血衄血,疮疡不敛,湿疹、湿疮,肺热咳嗽。In the composition of the present invention, catechu, bitter, astringent, slightly cold, returns to the lung and heart channels. Efficacy Promote blood circulation and relieve pain, stop bleeding and promote granulation, reduce dampness and sores, clear lung and resolve phlegm. For traumatic pain, traumatic hemorrhage, hematemesis and epistaxis, sores, eczema, eczema, cough due to lung heat.

本发明组合物中,千年健,辛,苦,归肝经以及肾经。有祛风湿、强筋骨的功效。可以治疗用于风寒湿痹,腰膝冷痛,拘挛麻木,筋骨痿软。In the composition of the present invention, Qiannianjian, pungent, and bitter are returned to the liver meridian and kidney meridian. It has the effect of dispelling rheumatism and strengthening bones and muscles. It can be used for treatment of wind-cold-damp arthralgia, cold pain in the waist and knees, spasm and numbness, and flaccidity of muscles and bones.

本发明组合物中,伸筋草,微苦、辛,温。归肝、脾、肾经。功能祛风除湿,舒筋活络。用于关节酸痛,屈伸不利。In the composition of the present invention, the herba chinensis is slightly bitter, pungent, and warm. Return liver, spleen, kidney channel. Function expelling wind and dampness, relaxing tendons and activating collaterals. It is used for sore joints and unfavorable flexion and extension.

本发明组合物中,木瓜,味酸,性温;归肝、脾、胃经。具有舒筋活络,和胃化湿的功效。主治风湿痹痛,肢体酸重,筋脉拘挛,吐泻转筋,脚气水肿。In the composition of the present invention, papaya is sour in taste and warm in nature; it belongs to the liver, spleen and stomach meridians. It has the effects of relaxing tendons and activating collaterals, and eliminating dampness in the stomach. Cure mainly rheumatic arthralgia, sore limbs, spasms of tendons, vomiting and diarrhea, and beriberi edema.

本发明组合物中,桑枝,味微苦,性平;归肝经。具有祛风湿、利关节的功效。主治风湿痹证,肩臂痛、关节酸痛麻木。In the composition of the present invention, Radix Mori has a slightly bitter taste and flat nature; it returns to the Liver Channel. It has the effects of dispelling rheumatism and benefiting joints. Indications of rheumatic arthralgia, shoulder and arm pain, joint pain and numbness.

本发明组合物中,白鲜皮,味苦,性寒。归脾、胃、膀胱经。 功能清热燥湿,祛风解毒。用于湿热疮毒,黄水淋漓,湿疹,风疹,疥癣疮癞,风湿热痹,黄疸尿赤。 In the composition of the present invention, the white fresh bark is bitter in taste and cold in nature. Return spleen, stomach, urinary bladder channel. Function clearing away heat and dampness, expelling wind and detoxification. For damp-heat sores, dripping yellow water, eczema, rubella, scabies sores, rheumatism-heat arthralgia, jaundice and red urine.

本发明组合物中,羌活,味辛、苦,性温。归膀胱、肾经。功能解表散寒,祛风除湿,止痛。用于风寒感冒,头痛项强,风湿痹痛,肩背酸痛。In the composition of the present invention, Notopterygium is pungent in taste, bitter in taste, and warm in nature. Return bladder, kidney channel. The function is to relieve the exterior and dissipate cold, expelling wind and dampness, and relieving pain. For wind-cold cold, headache, strong neck, rheumatic arthralgia, shoulder and back pain.

本发明组合物中,秦艽,味辛、苦,性平,归胃、肝胆经。功能祛风湿、通络止痛、退虚热、清湿热等功效。用于风湿痹痛,中风半身不遂,筋脉拘挛,骨节酸痛,湿热黄疸,骨蒸潮热,小儿疳积发热。In the composition of the present invention, Gentiana chinensis is pungent in taste, bitter, flat in nature, and returns to the stomach, liver and gallbladder meridian. Function: dispelling rheumatism, dredging collaterals and relieving pain, reducing asthenia-heat, clearing damp-heat and other effects. For rheumatic arthralgia, hemiplegia due to apoplexy, spasm of muscles and arteries, sore joints, damp-heat jaundice, hot flashes due to bone steaming, and malnutrition fever in children.

本发明组合物中,姜黄,味辛、苦,性温。归脾、肝经。有破血行气,通经止痛的功效。用于胸胁刺痛,闭经,癓瘕,风湿肩臂疼痛,跌扑肿痛。In the composition of the present invention, turmeric is pungent in taste, bitter in taste, and warm in nature. Return spleen, liver channel. It has the effects of dispelling blood and promoting qi, promoting menstruation and relieving pain. For chest pain, amenorrhea, lump in the abdomen, rheumatic shoulder and arm pain, tumbling and swelling.

本发明组合物中,佛手,味辛、苦、酸,性温。归经 归肝、脾、胃、肺经。功能 疏肝理气,和胃止痛,燥湿化痰。主治 用于肝胃气滞,胸胁胀痛,胃脘痞满,食少呕吐,咳嗽痰多。 In the composition of the present invention, bergamot is pungent in taste, bitter, sour, and warm in nature. Return to the liver, spleen, stomach, lung meridian. Function Soothe the liver and regulate qi, harmonize the stomach and relieve pain, dry dampness and resolve phlegm. Indications For stagnation of liver and stomach qi, distending pain in the chest and hypochondrium, fullness in the epigastric cavity, lack of appetite, vomiting, cough with excessive phlegm.

本发明组合物中,郁李仁,味辛、苦、甘,性平,归大肠经、小肠经、脾经。具有润肠通便、利水消肿的功效。用于津枯肠燥、食积气滞、腹胀便秘、水肿、脚气、小便不利。著名中医正骨专家刘寿山将其用作手部引经药。In the composition of the present invention, Yu Liren is pungent, bitter, sweet in taste, flat in nature, and belongs to the large intestine meridian, small intestine meridian, and spleen meridian. It has the effects of laxative, diuresis and swelling. Used for thirsty intestines, stagnation of Qi due to food accumulation, abdominal distension, constipation, edema, beriberi, and dysuria. Liu Shoushan, a well-known bone-setting expert in traditional Chinese medicine, used it as a medicine for guiding the meridians of the hands.

当归辛温活血调经,甘温补血,可化血瘀,通筋结,濡养筋脉,对于产时外伤造成恶血内留,血瘀经络不通,起到活血调经,对于后期筋骨脉失养继而出现肌肉萎缩、挛缩,起到养血养筋,为君药。黄芪辅助当归加强濡养和行气活血作用,并还具有消肿生肌作用;五灵脂辅助当归加强活血调经;木瓜舒筋活络、利关节,黄芪、五灵脂、木瓜共为臣药。儿茶、姜黄活血化瘀、通经活络;伸筋草、桑枝、白鲜皮、羌活、秦艽舒筋活络、祛风湿、利关节;狗脊补肝肾强筋骨;佛手为行气化痰;诸药共为佐药。郁李仁引导诸药至手,羌活引诸药至项肩背,桑枝引诸药至肩臂,共为使药。本组方重在调整肝脾肾,气血痰瘀湿、筋骨脉络、寒热综合考虑,并含颈、肩、臂、手引经药,合理搭配君臣佐使,疗效显著,无副作用。Angelica is pungent and warm, activates blood and regulates menstruation, warms and nourishes blood, can dissipate blood stasis, unblock tendon knots, moisten and nourish tendons and arteries, and treat intrapartum trauma that causes bad blood retention, blood stasis and meridian blockage, promotes blood circulation and regulates menstruation, and treats tendons, bones, and arteries in the later stage. Muscular atrophy and contracture then occur, which play a role in nourishing blood and nourishing tendons, which is the king's medicine. Astragalus assists angelica to strengthen nourishment, promote qi and blood circulation, and also has the effect of reducing swelling and promoting muscle growth; Wulingzhi assists angelica to strengthen blood circulation and regulate menstruation; papaya relaxes tendons, activates collaterals, and sharpens joints. Catechu and turmeric promote blood circulation and remove blood stasis, dredge meridian and collaterals; Shenjincao, mulberry branch, white fresh bark, notopterygium, Gentiana chinensis relax tendons and activate collaterals, dispel rheumatism, and sharpen joints; dog spine nourishes liver and kidney, strengthens muscles and bones; bergamot promotes qi and reduces phlegm ; All medicines are adjuvant altogether. Yu Liren guides all the medicines to the hands, Notopterygium guides the medicines to the neck and shoulders, and Sangzhi guides the medicines to the shoulders and arms, serving as envoys. This group of prescriptions focuses on adjusting the liver, spleen and kidney, qi, blood, phlegm and dampness, muscles and bones, and cold and heat.

本发明还提供一种配合康复治疗分娩性臂丛神经损伤的药浴中药的制备方法,其特征在于:The present invention also provides a preparation method of medicinal bath traditional Chinese medicine combined with rehabilitation to treat childbirth brachial plexus injury, which is characterized in that:

将所述药浴中药与水混合进行煎煮,过滤得中药药浴剂。The medicated bath medicine is mixed with water, decocted, and filtered to obtain the traditional Chinese medicine medicated bath preparation.

优选地,所述药浴中药与水的用量重量比为1:5~10。Preferably, the weight ratio of the medicine in the medicated bath to water is 1:5-10.

优选地,所述药浴中药与水混合后浸泡1~2h再进行煎煮。Preferably, the medicinal bath medicine is mixed with water, soaked for 1-2 hours, and then decocted.

优选地,所述煎煮沸腾后再煎的时间为15~20分钟。Preferably, the decocting time after boiling is 15-20 minutes.

优选地,所述药浴中药煎煮2次,混合两次药液,得药浴中药。Preferably, the medicinal bath medicine is decocted twice, and the medicinal solution is mixed twice to obtain the medicinal bath medicine.

有益技术效果:本发明提供了配合康复治疗分娩性臂丛神经损伤的药浴中药重在调整肝脾肾,并且气血痰瘀湿、筋骨脉络、寒热综合考虑,包含颈、肩、臂、手引经药,合理搭配君臣佐使,组方配伍得当。临床试验表明,本中药药浴剂配合康复治疗分娩性臂丛神经损伤,疗效提高显著,改善分娩性臂丛神经损伤患儿基础动作、手部功能、协调性和整体功能,无不良反应,使用方便。Beneficial technical effects: the present invention provides a medicated bath traditional Chinese medicine that cooperates with rehabilitation to treat childbirth brachial plexus injury. The classics and medicine are reasonably matched with the monarch, ministers and assistants, and the prescriptions are properly compatible. Clinical trials have shown that this traditional Chinese medicinal bath preparation combined with rehabilitation in the treatment of childbirth brachial plexus injury can significantly improve the curative effect, improve the basic movement, hand function, coordination and overall function of children with childbirth brachial plexus injury, and have no adverse reactions. convenient.

具体实施方式Detailed ways

下面结合实施例,对本发明作进一步地详细说明,但本发明实施方式并不仅限于此。The present invention will be described in further detail below in conjunction with the examples, but the embodiments of the present invention are not limited thereto.

本发明提供了一种配合康复治疗分娩性臂丛神经损伤的药浴中药,由以下重量份的原料组成:当归15-40份,黄芪15-30份,五灵脂15-30份,儿茶1-7份,千年健10-30份,木瓜15-30份,伸筋草10-30份,桑枝10-30份,白鲜皮10-30份,羌活10-30份,秦艽10-30份,姜黄10-30份,佛手5-20份,郁李仁5-20份。The invention provides a medicinal bath traditional Chinese medicine for rehabilitation treatment of childbirth brachial plexus injury. 1-7 parts, 10-30 parts of Qiannianjian, 15-30 parts of papaya, 10-30 parts of Shenjincao, 10-30 parts of mulberry branch, 10-30 parts of white fresh skin, 10-30 parts of Notopterygium, 10- 30 parts, turmeric 10-30 parts, bergamot 5-20 parts, Yu Liren 5-20 parts.

按重量份计,本发明所述药浴中药包括当归15-40份,优选为15-30份,更优选为20份。在本发明中,所述当归优选为伞形科植物当归Angelica sinensis (Oliv.)Diels的干燥根。In parts by weight, the medicated bath medicine of the present invention includes 15-40 parts of Angelica sinensis, preferably 15-30 parts, more preferably 20 parts. In the present invention, the angelica sinensis is preferably the dried root of Angelica sinensis (Oliv.) Diels of Umbelliferae.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括黄芪15-30份,优选为15-25份,更优选为18份。在本发明中,所述黄芪优选为豆科植物蒙古黄芪A.mongholicus Bunge的干燥根。Based on the dosage of angelica, in parts by weight, the medicated bath medicine of the present invention includes 15-30 parts of astragalus, preferably 15-25 parts, more preferably 18 parts. In the present invention, the Astragalus is preferably the dried root of A. mongholicus Bunge, a leguminous plant.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括五灵脂15-30份,优选为15-25份,更优选为18份。在本发明中,所述五灵脂优选为鼯鼠科动物橙足鼯鼠的干燥粪便。Based on the dosage of Angelica sinensis, in parts by weight, the medicated bath medicine of the present invention includes 15-30 parts of Wulingzhi, preferably 15-25 parts, more preferably 18 parts. In the present invention, the Wulingzhi is preferably the dried feces of the flying squirrel of the family Flying Squirrel.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括儿茶1-7份,优选为1-5份,更优选为3份。在本发明中,所述儿茶优选为豆科植物儿茶Acacia catechu (L.f.)Willci.的去皮枝、干的干燥煎膏。Based on the dosage of Angelica sinensis, in parts by weight, the medicated bath medicine of the present invention includes 1-7 parts of catechu, preferably 1-5 parts, more preferably 3 parts. In the present invention, the catechu is preferably a decoction of peeled sticks and dried of Acacia catechu (L.f.) Willci.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括千年健10-30份,优选为15-20,更优选为15份。在本发明中,所述千年健优选为天南星科植物千年健Homalomena occulta(Lour.)Schott的干燥根茎。Based on the dosage of angelica, in parts by weight, the medicated bath medicine of the present invention includes 10-30 parts of Qiannianjian, preferably 15-20 parts, more preferably 15 parts. In the present invention, the millennium occulta is preferably the dried rhizome of Homalomena occulta (Lour.) Schott, a plant of the family Araceae.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括木瓜15-30份,优选为15-25份,更优选为18份。在本发明中,所述木瓜优选为蔷薇科植物贴梗海棠Chaenomelesspeciosa(Sweet)Nakai的干燥近成熟果实。Based on the dosage of angelica, in parts by weight, the medicated bath medicine of the present invention includes 15-30 parts of papaya, preferably 15-25 parts, more preferably 18 parts. In the present invention, the papaya is preferably the dried near-ripe fruit of the Rosaceae plant Chaenomeles speciosa (Sweet) Nakai.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括伸筋草10-30份,优选为15-20,更优选为15份。在本发明中,所述伸筋草优选为石松科植物石松LycopodiumjaPonicum Thunb.的干燥全草。Based on the dosage of Angelica sinensis, in parts by weight, the medicated bath medicine of the present invention includes 10-30 parts, preferably 15-20 parts, more preferably 15 parts, of Shenjincao. In the present invention, the Streptococcus is preferably the dry whole herb of LycopodiumjaPonicum Thunb.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括桑枝10-30份,优选为15-20,更优选为15份。在本发明中,所述桑枝优选为桑科植物桑Morus alba L.的干燥嫩枝。Based on the dosage of Angelica sinensis, in parts by weight, the medicated bath medicine of the present invention includes 10-30 parts of mulberry branches, preferably 15-20 parts, more preferably 15 parts. In the present invention, the mulberry branches are preferably dry shoots of Morus alba L., a plant of the Moraceae family.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括白鲜皮10-30份,优选为15-20,更优选为15份。在本发明中,所述白鲜皮优选为芸香科植物白鲜Dictamnusdasycarpus Turcz.的干燥根皮。Based on the dosage of Angelica sinensis, in parts by weight, the medicated bath medicine of the present invention includes 10-30 parts, preferably 15-20 parts, and more preferably 15 parts, of Radix Cortex. In the present invention, the fresh bark of Dictamnus dasycarpus is preferably the dried root bark of Dictamnus dasycarpus Turcz.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括羌活10-30份,优选为15-20,更优选为15份。在本发明中,所述羌活优选为伞形科植物羌活(背翅芹)Notopterygiumincisum Ting ex H. T. Chang的干燥根茎。Based on the dosage of angelica, in parts by weight, the medicated bath medicine of the present invention includes notopterygium in 10-30 parts, preferably in 15-20 parts, more preferably in 15 parts. In the present invention, the notopterygium is preferably the dried rhizome of Notopterygiumincisum Ting ex H. T. Chang, an Umbelliferae plant notopterygiumincisum Ting ex H. T. Chang.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括秦艽10-30份,优选为15-20,更优选为15份。在本发明中,所述秦艽优选为龙胆科植物秦艽Gentianamacrophylla Pall.的干燥根。Based on the dosage of Angelica sinensis, in parts by weight, the medicated bath medicine of the present invention includes 10-30 parts, preferably 15-20 parts, more preferably 15 parts, of Gentiana chinensis. In the present invention, the Gentiana macrophylla Pall. is preferably the dried root of the Gentianae plant Gentiana macrophylla Pall.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括姜黄10-30份,优选为15-20,更优选为15份。在本发明中,所述姜黄优选为姜科植物姜黄Curcuma longa L.的干燥根茎。Based on the dosage of Angelica sinensis, in parts by weight, the medicated bath medicine of the present invention includes 10-30 parts of turmeric, preferably 15-20 parts, more preferably 15 parts. In the present invention, the turmeric is preferably the dried rhizome of Curcuma longa L., a plant of the ginger family.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括佛手5-20份,优选为5-15份,更优选为10份。在本发明中,所述佛手优选为芸香科植物佛手CitrusmedicaLvar.sarcodac-tylisSwingle的干燥果实。Based on the dosage of Angelica sinensis, in parts by weight, the medicated bath medicine of the present invention includes 5-20 parts of bergamot, preferably 5-15 parts, more preferably 10 parts. In the present invention, the bergamot is preferably the dried fruit of Rutaceae bergamot CitrusmedicaLvar.sarcodac-tylisSwingle.

以当归的用量为基准,按重量份计,本发明所述药浴中药包括郁李仁5-20份,优选为5-15份,更优选为6份。在本发明中,所述郁李仁优选为蔷薇科植物郁李Prunus japonicaThunb.的干燥成熟种子。Based on the dosage of angelica, in parts by weight, the medicated bath medicine of the present invention includes 5-20 parts of Yu Liren, preferably 5-15 parts, more preferably 6 parts. In the present invention, the Prunus japonica Thunb. is preferably the dry mature seeds of the Rosaceae plant Prunus japonica Thunb.

优选地,所述药浴中药由以下重量份的原料组成:当归15-30份,黄芪15-25份,五灵脂15-20份,儿茶1-5份,千年健15-20份,木瓜15-20份,伸筋草15-20份,桑枝15-20份,白鲜皮15-20份,羌活15-20份,秦艽15-20份,姜黄15-20份,佛手5-15份,郁李仁5-15份。Preferably, the medicinal bath medicine is composed of the following raw materials in parts by weight: 15-30 parts of angelica, 15-25 parts of astragalus, 15-20 parts of Wulingzhi, 1-5 parts of catechu, 15-20 parts of Qiannianjian, 15-20 parts of papaya, 15-20 parts of Shenjincao, 15-20 parts of mulberry branch, 15-20 parts of white fresh skin, 15-20 parts of notopterygium, 15-20 parts of Gentiana, 15-20 parts of turmeric, 5- 15 copies, Yu Liren 5-15 copies.

优选地,所述药浴中药由以下重量份的原料组成:当归20份,黄芪18份,五灵脂18份,儿茶3份,千年健15份,木瓜18份,伸筋草15份,桑枝15份,白鲜皮15份,羌活15份,秦艽15份,姜黄15份,佛手10份,郁李仁6份。Preferably, the medicated bath medicine consists of the following raw materials in parts by weight: 20 parts of angelica, 18 parts of astragalus, 18 parts of Wulingzhi, 3 parts of catechu, 15 parts of Qiannianjian, 18 parts of papaya, 15 parts of Shenjincao, 15 parts of mulberry branch, 15 parts of white fresh skin, 15 parts of Qianghuo, 15 parts of Gentiana chinensis, 15 parts of turmeric, 10 parts of bergamot, and 6 parts of Yu Liren.

本发明还提供一种配合康复治疗分娩性臂丛神经损伤的药浴中药的制备方法,其特征在于:The present invention also provides a preparation method of medicinal bath traditional Chinese medicine combined with rehabilitation to treat childbirth brachial plexus injury, which is characterized in that:

将所述药浴中药与水混合进行煎煮,过滤,得中药药浴剂。The medicated bath medicine is mixed with water, decocted and filtered to obtain the traditional Chinese medicine medicated bath preparation.

优选地,所述药浴中药与水的用量重量比为1:5~10。Preferably, the weight ratio of the medicine in the medicated bath to water is 1:5-10.

优选地,所述药浴中药与水混合后浸泡1~2h再进行煎煮。Preferably, the medicinal bath medicine is mixed with water, soaked for 1-2 hours, and then decocted.

优选地,所述煎煮沸腾后再煎的时间为15~20分钟。Preferably, the decocting time after boiling is 15-20 minutes.

优选地,所述药浴中药煎煮2次,混合两次药液,得中药药浴剂。Preferably, the medicinal bath medicine is decocted twice, and the medicinal liquid is mixed twice to obtain a traditional Chinese medicinal bath preparation.

为了更好地理解本发明,下面结合实施例进一步阐明本发明的内容,但本发明的内容不仅仅局限于下面的实施例。In order to better understand the present invention, the content of the present invention is further illustrated below in conjunction with the examples, but the content of the present invention is not limited to the following examples.

实施例1Example 1

一种配合康复治疗分娩性臂丛神经损伤的药浴中药,由以下重量份数的原料组成:当归20份,黄芪18份,五灵脂18份,儿茶3份,千年健15份,木瓜18份,伸筋草15份,桑枝15份,白鲜皮15份,羌活15份,秦艽15份,姜黄15份,佛手10份,郁李仁6份。 A medicated bath traditional Chinese medicine for rehabilitation treatment of childbirth brachial plexus injury, which is composed of the following raw materials in parts by weight: 20 parts of angelica, 18 parts of astragalus, 18 parts of Wulingzhi, 3 parts of catechu, 15 parts of Qiannianjian, papaya 18 parts, 15 parts of Shenjincao, 15 parts of mulberry branch, 15 parts of white fresh skin, 15 parts of Qianghuo, 15 parts of Gentiana chinensis, 15 parts of turmeric, 10 parts of bergamot, and 6 parts of Yu Liren.

取上述药浴中药,加入1500mL水,浸泡2h,慢火煮开后熬制30分钟,过滤,得第一次药液。所述药浴中药加入1000mL水再次煎煮,过滤,得第二次药液。混合两次药液,即得中药药浴剂。Take the above-mentioned medicated bath medicine, add 1500mL of water, soak for 2 hours, boil for 30 minutes after slow fire, filter to get the first medicinal liquid. Add 1000mL of water to the medicated bath medicine, decoct it again, and filter to obtain the second medicinal liquid. Mix the medicinal liquid twice to obtain the traditional Chinese medicinal bath agent.

使用方法:将所述中药药浴剂加入置于浴缸中,水温控制在 37 ℃左右,每次药浴20分钟,1 天1次。Method of use: add the traditional Chinese medicine medicinal bath agent into the bathtub, control the water temperature at about 37 ℃, take a medicinal bath for 20 minutes each time, once a day.

实施例2Example 2

一种配合康复治疗分娩性臂丛神经损伤的药浴中药,由以下重量份数的原料组成:当归25份,黄芪20份,五灵脂2份,儿茶3份,千年健18份,木瓜20份,伸筋草18份,桑枝18份,白鲜皮18份,羌活18份,秦艽18份,姜黄18份,佛手12份,郁李仁12份。A medicated bath traditional Chinese medicine for rehabilitation treatment of childbirth brachial plexus injury, which is composed of the following raw materials in parts by weight: 25 parts of angelica, 20 parts of astragalus, 2 parts of Wulingzhi, 3 parts of catechu, 18 parts of Qiannianjian, papaya 20 parts, 18 parts of Shenjincao, 18 parts of mulberry branch, 18 parts of white fresh skin, 18 parts of Qianghuo, 18 parts of Gentiana chinensis, 18 parts of turmeric, 12 parts of bergamot, and 12 parts of Yu Liren.

取上述药浴中药,加入1500mL水,浸泡2h,慢火煮开后熬制30分钟,过滤,得第一次药液。所述药浴中药加入1000mL水再次煎煮,过滤,得第二次药液。混合两次药液,即得中药药浴剂。Take the above-mentioned medicated bath medicine, add 1500mL of water, soak for 2 hours, boil for 30 minutes after slow fire, filter to get the first medicinal liquid. Add 1000mL of water to the medicated bath medicine, decoct it again, and filter to obtain the second medicinal solution. Mix the medicinal liquid twice to obtain the traditional Chinese medicinal bath agent.

使用方法:将所述中药药浴剂与药浴中药加入置于浴缸中,水温控制在 37 ℃左右, 每次药浴20-30分钟,1 天1次。Method of use: add the traditional Chinese medicinal bath agent and medicinal bath medicine into the bathtub, control the water temperature at about 37°C, and take a medicinal bath for 20-30 minutes each time, once a day.

实施例3Example 3

当归30份,黄芪25份,五灵脂25份,儿茶3份,千年健20份,木瓜25份,伸筋草20份,桑枝20份,白鲜皮20份,羌活20份,秦艽20份,姜黄20份,佛手15份,郁李仁15份。 30 parts of angelica, 25 parts of astragalus, 25 parts of wulingzhi, 3 parts of catechu, 20 parts of Qiannianjian, 25 parts of papaya, 20 parts of Shenjincao, 20 parts of mulberry branch, 20 parts of white fresh skin, 20 parts of notopterygium, Gentiana japonica 20 parts, 20 parts of turmeric, 15 parts of bergamot, 15 parts of Yu Liren.

取上述药浴中药,加入2000mL水,浸泡2h,慢火煮开后熬制30分钟,过滤,得第一次药液。所述药浴中药加入1000mL水再次煎煮,过滤,得第二次药液。混合两次药液,即得中药药浴剂。Take the above medicated bath traditional Chinese medicine, add 2000mL of water, soak for 2 hours, boil for 30 minutes after slow fire, filter to get the first medicinal liquid. Add 1000mL of water to the medicated bath medicine, decoct it again, and filter to obtain the second medicinal solution. Mix the medicinal liquid twice to obtain the traditional Chinese medicinal bath agent.

使用方法:将所述中药药浴剂加入置于浴缸中,水温控制在 37 ℃左右,每次药浴20-30分钟,1 天1次。Method of use: add the traditional Chinese medicine medicinal bath agent into the bathtub, control the water temperature at about 37 ℃, take 20-30 minutes of medicinal bath each time, once a day.

本发明药浴中药的药效临床试验Drug effect clinical test of the medicated bath traditional Chinese medicine of the present invention

本研究采用病例对照研究方法,依据治疗方法选取分娩性臂丛神经损伤患儿88例,分为观察组和对照组。仅常规康复治疗者为对照组,纳入44例。其中男 25 例,女 19例; 年龄2~24个月,中位数 12 个月; 左、右侧患病分别为 23、21 例; Tassin 分型: Ⅰ、Ⅱ、Ⅲ、Ⅳ型分别为 10、17、16、1 例。常规康复结合实施例1中药药浴治疗的患者为观察组,纳入44例,其中男 27 例,女 17 例; 年龄 2~24 个月,中位数12个月; 左、右侧患病分别为 19、25 例; Tassin 分型: Ⅰ、Ⅱ、Ⅲ、Ⅳ型分别为 11、16、15、2例。2 组一般资料差异无统计学意义( P > 0. 05) ,具有可比性。 In this study, a case-control study method was adopted, and 88 children with childbirth brachial plexus injury were selected according to the treatment method and divided into observation group and control group. Only routine rehabilitation treatment was used as the control group, and 44 cases were included. Among them, there were 25 males and 19 females; the age ranged from 2 to 24 months, with a median of 12 months; 23 and 21 cases were affected on the left and right sides respectively; Tassin types: Ⅰ, Ⅱ, Ⅲ, and Ⅳ were respectively 10, 17, 16, 1 case. Patients who received routine rehabilitation combined with traditional Chinese medicine dipping treatment in Example 1 were the observation group, including 44 cases, including 27 males and 17 females; aged 2 to 24 months, with a median of 12 months; 19, 25 cases; Tassin classification: Ⅰ, Ⅱ, Ⅲ, Ⅳ types were 11, 16, 15, 2 cases. There was no significant difference in general data between the two groups (P > 0.05), and they were comparable.

诊断标准符合《臂丛神经损伤临床诊疗与康复》标准: 巨大儿( 出生时体重 > 4kg) 或有难产、滞产及不适当的助产史; 出生后一侧上肢部分( 或全部) 立即出现软瘫;经神经肌电图检查确诊。The diagnostic criteria are in line with the "Clinical Diagnosis, Treatment and Rehabilitation of Brachial Plexus Injury": macrosomia (weight at birth > 4kg) or history of dystocia, delayed labor and inappropriate midwifery; part (or all) of one upper limb appears immediately after birth Facile paralysis; confirmed by neuroelectromyography.

纳入标准 符合分娩性臂丛神经损伤诊断标准; 单侧臂丛神经损伤;年龄2月到24月; 监护人签署知情同意书。Inclusion criteria Meet the diagnostic criteria for childbirth brachial plexus injury; unilateral brachial plexus injury; aged 2 to 24 months; guardian signed informed consent.

排除标准 双侧臂丛神经损伤; 脑性瘫痪引起的上肢运动障碍; 肩关节脱位、锁骨骨折、桡骨骨折等上肢骨关节损伤; 患有严重心血管疾病、癫痫及精神疾病、血液系统疾病。Exclusion criteria Bilateral brachial plexus injury; upper limb movement disorder caused by cerebral palsy; shoulder dislocation, clavicle fracture, radius fracture and other upper limb bone and joint injuries; severe cardiovascular disease, epilepsy, mental disease, and blood system disease.

治疗方法treatment method

对照组: 给予针灸、推拿、康复训练等常规康复治疗措施。①针灸治疗:统一培训临床医生操作,针刺肩三针( 肩髃、肩髎、肩贞) 、曲池、合谷穴,消毒后25 mm 毫针刺入穴位,平补平泻,得气后即可出针。工作日每天1 次,3 个月为 1 个疗程。②推拿治疗:由经统一培训的临床医生施行,循患侧手三阴、手三阳经筋推拿,并根据患儿临床症状对症推拿治疗,连续治疗,工作日每天1次,每次10分钟。工作日每天1 次,3 个月为 1 个疗程。③康复训练: 由统一培训专业康复训练师操作,行肩胛带后伸内旋,肩关节屈曲、外旋、外展,肘关节屈曲、伸展,前臂旋前、旋后,腕关节背伸、掌屈,腕关节向桡侧、尺侧运动,手指抓握、伸展、灵活性及协调性训练。工作日每天 1 次,每次 20 分钟,3个月为1个疗程。Control group: received routine rehabilitation measures such as acupuncture, massage, and rehabilitation training. ① Acupuncture and moxibustion treatment: Uniformly trained clinicians to operate, needling three needles on the shoulder (Jianlian, Jianliao, Jianzhen), Quchi, and Hegu points, after disinfection, 25 mm needles were inserted into the acupoints, tonify and relieve, and get qi The needle is ready to go. Once a day on weekdays, 3 months is a course of treatment. ②Massage treatment: performed by uniformly trained clinicians, massage along the tendons of the three yin and three yang meridians of the affected side, and symptomatic massage treatment according to the clinical symptoms of the child, continuous treatment, once a day on weekdays, 10 minutes each time . Once a day on weekdays, 3 months is a course of treatment. ③Rehabilitation training: Operated by a professional rehabilitation trainer with unified training, shoulder girdle extension and internal rotation, shoulder joint flexion, external rotation, abduction, elbow joint flexion and extension, forearm pronation and supination, wrist dorsiflexion, palm Flexion, wrist movement to the radial side and ulnar side, finger grip, extension, flexibility and coordination training. 1 time a day on weekdays, 20 minutes each time, 3 months as a course of treatment.

观察组:在对照组的基础上,加用实施例1的方案,工作日每天1 次,3 个月为 1个疗程。Observation group: On the basis of the control group, the regimen of Example 1 was added, once a day on weekdays, and 3 months was a course of treatment.

观察指标与方法Observation indicators and methods

治疗前后采用分娩性臂丛神经损伤功能障碍评估表( OBPIF)进行评价,包括基础动作( 肩关节屈曲、肩关节水平外展、肘伸展、肘屈曲、前臂旋前旋后) 、手部功能( 腕背伸、腕掌屈、五指屈曲、五 指 伸 展、勾 状 抓 握、球 状 抓 握、对捏、侧捏、拇指分别与其余四指对指) 、协调性( 肩关节内收位屈曲、肩屈曲90°、肘伸直、前臂旋前旋后、手触腰椎、鼓掌、扔球、腕环形运动) 3 大类。0 分: 不能完成; 1 分: 完成较差; 2分: 完成较好; 3分: 完成充分。Obstetric Brachial Plexus Injury Functional Impairment Assessment Form (OBPIF) was used to evaluate before and after treatment, including basic movements (shoulder joint flexion, shoulder joint horizontal abduction, elbow extension, elbow flexion, forearm pronation and supination), hand function ( Wrist dorsiflexion, wrist palmar flexion, five-finger flexion, five-finger extension, hook grip, ball grip, pair pinch, side pinch, thumb and other four fingers respectively), coordination (shoulder joint adduction position flexion, shoulder 90° flexion, elbow extension, forearm pronation and supination, hand touch lumbar spine, clapping, ball throwing, wrist circular movement) 3 categories. 0 points: not completed; 1 point: poorly completed; 2 points: relatively well completed; 3 points: fully completed.

统计学方法Statistical method

采用 SPSS 23. 0 统计软件对所得数据进行分析。等级资料采用秩和检验; 计量资料以均数±标准差表示,比较采用独立样本 t 检验。P< 0. 05 为差异有统计学意义。The obtained data were analyzed by SPSS 23.0 statistical software. Rank sum test was used for rank data; measurement data was expressed as mean ± standard deviation, and independent sample t test was used for comparison. P<0.05 means the difference is statistically significant.

疗效判定标准Efficacy criteria

痊愈: 肌力、肌萎缩完全恢复正常,上肢及手功能完全正常,症状、体征完全消失。显效:肌力、肌萎缩明显改善,上肢及手功能基本正常,症状、体征基本消失。有效: 肌力提高 1 级以上,肌肉萎缩有所改善,上肢及手功能活动有改善。无效:肌力、肌肉萎缩及上肢、手的功能均无改善。Recovery: Muscle strength and muscle atrophy completely returned to normal, upper limb and hand functions were completely normal, symptoms and signs disappeared completely. Significant effect: muscle strength and muscle atrophy are significantly improved, upper limb and hand functions are basically normal, and symptoms and signs basically disappear. Effective: Muscle strength improved by more than 1 grade, muscle atrophy improved, and upper limb and hand functional activities improved. Ineffective: Muscle strength, muscle atrophy, and upper limb and hand functions did not improve.

结果result

2 组治疗前后 OBPIF 评分比较Comparison of OBPIF scores before and after treatment in the two groups

2 组基础动作评分、手部功能评分、协调性评分、总分均较治疗前升高; 治疗后观察组各项评分改善优于对照组( P < 0.05) 。见表 1-4。The basic movement scores, hand function scores, coordination scores, and total scores of the two groups were all higher than those before treatment; after treatment, the scores of the observation group improved better than those of the control group ( P < 0.05). See Table 1-4.

表1 两组患者基础动作评分比较Table 1 Comparison of basic movement scores between the two groups

Figure SMS_1
Figure SMS_1

表2 两组患者手部功能评分比较Table 2 Comparison of hand function scores between the two groups

Figure SMS_2
Figure SMS_2

表3两组患者协调性评分比较Table 3 Comparison of coordination scores between the two groups of patients

Figure SMS_3
Figure SMS_3

表4 两组患者OBPIF评分比较Table 4 Comparison of OBPIF scores between the two groups

Figure SMS_4
Figure SMS_4

观察组痊愈6例,显效25例,有效13例,无效0例;对照组痊愈4例,显效16例,有效23例,无效1例;差异有统计学意义,观察组临床疗效优于对照组,(Z=-2.259,P=0.024)见表5。In the observation group, 6 cases were cured, 25 cases were markedly effective, 13 cases were effective, and 0 cases were ineffective; in the control group, 4 cases were cured, 16 cases were markedly effective, 23 cases were effective, and 1 case was ineffective; the difference was statistically significant, and the clinical curative effect of the observation group was better than that of the control group , (Z=-2.259, P=0.024) see Table 5.

表5 两组患者临床疗效比较Table 5 Comparison of clinical curative effect of two groups of patients

Figure SMS_5
Figure SMS_5

不良反应观察Adverse reaction observation

本试验未发现不良反应,无患儿出现因本组合物出现的皮疹。No adverse reaction was found in this test, and no child had any rash due to the composition.

本药浴中药配合康复治疗分娩性臂丛神经损伤,疗效提高显著,改善了分娩性臂丛神经损伤患儿基础动作、手部功能、协调性和整体功能,无不良反应,使用方便。The medicated bath traditional Chinese medicine combined with rehabilitation treatment of childbirth brachial plexus injury has significantly improved curative effect, improved basic movement, hand function, coordination and overall function of children with childbirth brachial plexus injury, has no adverse reactions, and is convenient to use.

以上所述仅是本发明的优选实施方式,应当指出,对于本技术领域的普通技术人员来说,在不脱离本发明原理的前提下,还可以做出若干改进和润饰,这些改进和润饰也应视为本发明的保护范围。The above is only a preferred embodiment of the present invention, it should be pointed out that, for those of ordinary skill in the art, without departing from the principle of the present invention, some improvements and modifications can also be made, and these improvements and modifications can also be made. It should be regarded as the protection scope of the present invention.

Claims (7)

1.一种配合康复治疗分娩性臂丛神经损伤的药浴中药,其特征在于,由以下重量份的原料组成:当归15-40份,黄芪15-30份,五灵脂15-30份,儿茶1-7份,千年健10-30份,木瓜15-30份,伸筋草10-30份,桑枝10-30份,白鲜皮10-30份,羌活10-30份,秦艽10-30份,姜黄10-30份,佛手5-20份,郁李仁5-20份。1. A medicated bath traditional Chinese medicine for rehabilitation treatment of childbirth brachial plexus injury, characterized in that it is made up of the raw materials of the following parts by weight: 15-40 parts of Angelica sinensis, 15-30 parts of Radix Astragali, 15-30 parts of Wulingzhi, 1-7 parts of catechu, 10-30 parts of Qiannianjian, 15-30 parts of Chinese papaya, 10-30 parts of Shenjincao, 10-30 parts of mulberry branch, 10-30 parts of white fresh bark, 10-30 parts of notopterygium, Gentiana officinalis 10-30 parts, turmeric 10-30 parts, bergamot 5-20 parts, Yu Liren 5-20 parts. 2.根据权利要求1所述的药浴中药,其特征在于,所述药浴中药由以下重量份的原料组成:当归15-30份,黄芪15-25份,五灵脂15-20份,儿茶1-5份,千年健15-20份,木瓜15-20份,伸筋草15-20份,桑枝15-20份,白鲜皮15-20份,羌活15-20份,秦艽15-20份,姜黄15-20份,佛手5-15份,郁李仁5-15份。2. The medicated bath Chinese medicine according to claim 1, characterized in that, the medicated bath Chinese medicine is made up of the following raw materials in parts by weight: 15-30 parts of Angelica sinensis, 15-25 parts of Radix Astragali, 15-20 parts of Wulingzhi, 1-5 parts of catechu, 15-20 parts of Qiannianjian, 15-20 parts of papaya, 15-20 parts of Shenjincao, 15-20 parts of mulberry branch, 15-20 parts of white fresh skin, 15-20 parts of notopterygium, Gentiana chinensis 15-20 parts, 15-20 parts of turmeric, 5-15 parts of bergamot, 5-15 parts of Yu Liren. 3.根据权利要求1所述的药浴中药,其特征在于,所述药浴中药由以下重量份的原料组成:当归20份,黄芪18份,五灵脂18份,儿茶3份,千年健15份,木瓜18份,伸筋草15份,桑枝15份,白鲜皮15份,羌活15份,秦艽15份,姜黄15份,佛手10份,郁李仁6份。3. The medicated bath medicine according to claim 1, characterized in that, said medicated bath medicine consists of the following raw materials in parts by weight: 20 parts of angelica, 18 parts of astragalus, 18 parts of wulingzhi, 3 parts of catechu, millennium 15 parts of Jian, 18 parts of papaya, 15 parts of Shenjincao, 15 parts of mulberry branch, 15 parts of white fresh skin, 15 parts of notopterygium, 15 parts of Gentiana chinensis, 15 parts of turmeric, 10 parts of bergamot, and 6 parts of Yu Liren. 4.根据权利要求1-3任一所述的药浴中药的制备方法,其特征在于:将中药原料与水混合进行煎煮,过滤,即得。4. The preparation method of the dipped traditional Chinese medicine according to any one of claims 1-3, characterized in that: the raw materials of the traditional Chinese medicine are mixed with water, decocted, filtered, and obtained. 5.根据权利要求4所述的药浴中药的制备方法,其特征在于:所述中药与水的用量重量比为1:5-10。5 . The method for preparing traditional Chinese medicine in medicated bath according to claim 4 , characterized in that: the weight ratio of the traditional Chinese medicine to water is 1:5-10. 6.根据权利要求4所述的药浴中药的制备方法,其特征在于:所述中药与水混合后浸泡1~2h再进行煎煮。6 . The method for preparing traditional Chinese medicine in medicinal bath according to claim 4 , characterized in that: the traditional Chinese medicine is mixed with water, soaked for 1-2 hours, and then decocted. 7.根据权利要求4所述的药浴中药的制备方法,其特征在于:所述煎煮的时间为水开后为20~30分钟。7. The preparation method of dipped traditional Chinese medicine according to claim 4, characterized in that: the decocting time is 20-30 minutes after the water is boiled.
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