CN115887338A - Composition with scalp anti-aging effect and preparation method and application thereof - Google Patents
Composition with scalp anti-aging effect and preparation method and application thereof Download PDFInfo
- Publication number
- CN115887338A CN115887338A CN202211548359.3A CN202211548359A CN115887338A CN 115887338 A CN115887338 A CN 115887338A CN 202211548359 A CN202211548359 A CN 202211548359A CN 115887338 A CN115887338 A CN 115887338A
- Authority
- CN
- China
- Prior art keywords
- composition
- scalp
- panthenol
- allantoin
- fermentation product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 84
- 238000002360 preparation method Methods 0.000 title claims abstract description 26
- 210000004761 scalp Anatomy 0.000 title abstract description 82
- 230000003712 anti-aging effect Effects 0.000 title abstract description 48
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims abstract description 80
- 239000000047 product Substances 0.000 claims abstract description 49
- 238000000855 fermentation Methods 0.000 claims abstract description 43
- 230000004151 fermentation Effects 0.000 claims abstract description 43
- 239000000706 filtrate Substances 0.000 claims abstract description 43
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims abstract description 40
- 229960000458 allantoin Drugs 0.000 claims abstract description 40
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims abstract description 39
- 229940101267 panthenol Drugs 0.000 claims abstract description 39
- 235000020957 pantothenol Nutrition 0.000 claims abstract description 39
- 239000011619 pantothenol Substances 0.000 claims abstract description 39
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims abstract description 36
- 235000017491 Bambusa tulda Nutrition 0.000 claims abstract description 36
- 241001330002 Bambuseae Species 0.000 claims abstract description 36
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims abstract description 36
- 239000011425 bamboo Substances 0.000 claims abstract description 36
- 238000000034 method Methods 0.000 claims abstract description 7
- 230000008569 process Effects 0.000 claims abstract description 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 22
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims description 22
- 241000282458 Ursus sp. Species 0.000 claims description 15
- 239000002453 shampoo Substances 0.000 claims description 12
- 241000196324 Embryophyta Species 0.000 claims description 11
- 210000004209 hair Anatomy 0.000 claims description 11
- 238000003756 stirring Methods 0.000 claims description 7
- 241000543810 Sasa veitchii Species 0.000 claims description 5
- 239000002537 cosmetic Substances 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 241000745988 Phyllostachys Species 0.000 claims description 3
- 241000222481 Schizophyllum commune Species 0.000 claims description 2
- 239000006071 cream Substances 0.000 claims description 2
- 238000009472 formulation Methods 0.000 claims description 2
- 241000222480 Schizophyllum Species 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 229940081969 saccharomyces cerevisiae Drugs 0.000 claims 1
- 241000235347 Schizosaccharomyces pombe Species 0.000 abstract description 17
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 abstract description 11
- 230000032683 aging Effects 0.000 abstract description 11
- 230000000694 effects Effects 0.000 abstract description 10
- 239000000126 substance Substances 0.000 abstract description 8
- 210000003128 head Anatomy 0.000 abstract description 4
- 230000003647 oxidation Effects 0.000 abstract description 4
- 238000007254 oxidation reaction Methods 0.000 abstract description 4
- 244000153955 Reynoutria sachalinensis Species 0.000 abstract description 3
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 abstract description 3
- 150000001875 compounds Chemical class 0.000 abstract description 3
- 230000035699 permeability Effects 0.000 abstract description 2
- 230000002000 scavenging effect Effects 0.000 abstract description 2
- 239000002904 solvent Substances 0.000 abstract description 2
- 230000002349 favourable effect Effects 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 72
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 31
- 238000005336 cracking Methods 0.000 description 9
- 150000003254 radicals Chemical class 0.000 description 8
- 210000003491 skin Anatomy 0.000 description 8
- 208000025174 PANDAS Diseases 0.000 description 6
- 208000021155 Paediatric autoimmune neuropsychiatric disorders associated with streptococcal infection Diseases 0.000 description 6
- 240000004718 Panda Species 0.000 description 6
- 235000016496 Panda oleosa Nutrition 0.000 description 6
- 238000002835 absorbance Methods 0.000 description 6
- 230000007794 irritation Effects 0.000 description 6
- WQGWDDDVZFFDIG-UHFFFAOYSA-N pyrogallol Chemical compound OC1=CC=CC(O)=C1O WQGWDDDVZFFDIG-UHFFFAOYSA-N 0.000 description 6
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 230000003078 antioxidant effect Effects 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 210000003780 hair follicle Anatomy 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 238000010998 test method Methods 0.000 description 4
- 229920002385 Sodium hyaluronate Polymers 0.000 description 3
- 239000003963 antioxidant agent Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 229940010747 sodium hyaluronate Drugs 0.000 description 3
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical group [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 3
- 230000002195 synergetic effect Effects 0.000 description 3
- 201000004384 Alopecia Diseases 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 206010018910 Haemolysis Diseases 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 240000003915 Lophatherum gracile Species 0.000 description 2
- 244000302661 Phyllostachys pubescens Species 0.000 description 2
- 235000003570 Phyllostachys pubescens Nutrition 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 230000004992 fission Effects 0.000 description 2
- 229930003935 flavonoid Natural products 0.000 description 2
- -1 flavonoid compound Chemical class 0.000 description 2
- 235000017173 flavonoids Nutrition 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 229930182830 galactose Natural products 0.000 description 2
- 230000008588 hemolysis Effects 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 239000002304 perfume Substances 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 229940079877 pyrogallol Drugs 0.000 description 2
- 230000005808 skin problem Effects 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 239000011701 zinc Substances 0.000 description 2
- 229910052725 zinc Inorganic materials 0.000 description 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- VFKZECOCJCGZQK-UHFFFAOYSA-M 3-hydroxypropyl(trimethyl)azanium;chloride Chemical compound [Cl-].C[N+](C)(C)CCCO VFKZECOCJCGZQK-UHFFFAOYSA-M 0.000 description 1
- 244000205574 Acorus calamus Species 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
- 235000011996 Calamus deerratus Nutrition 0.000 description 1
- 244000303965 Cyamopsis psoralioides Species 0.000 description 1
- 208000001840 Dandruff Diseases 0.000 description 1
- JDRSMPFHFNXQRB-CMTNHCDUSA-N Decyl beta-D-threo-hexopyranoside Chemical compound CCCCCCCCCCO[C@@H]1O[C@H](CO)C(O)[C@H](O)C1O JDRSMPFHFNXQRB-CMTNHCDUSA-N 0.000 description 1
- 241000157862 Dicamptodontidae Species 0.000 description 1
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 description 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 description 1
- SUZRRICLUFMAQD-UHFFFAOYSA-N N-Methyltaurine Chemical compound CNCCS(O)(=O)=O SUZRRICLUFMAQD-UHFFFAOYSA-N 0.000 description 1
- 241000235070 Saccharomyces Species 0.000 description 1
- 241000985696 Tecoma Species 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 241000282446 Ursus Species 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 231100000360 alopecia Toxicity 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 238000006701 autoxidation reaction Methods 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 description 1
- 230000019771 cognition Effects 0.000 description 1
- 229940073499 decyl glucoside Drugs 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000012154 double-distilled water Substances 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 230000037149 energy metabolism Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 230000007760 free radical scavenging Effects 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000004898 kneading Methods 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000004792 oxidative damage Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 229960003330 pentetic acid Drugs 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- HVFAVOFILADWEZ-UHFFFAOYSA-M sodium;2-[2-(dodecanoylamino)ethyl-(2-hydroxyethyl)amino]acetate Chemical compound [Na+].CCCCCCCCCCCC(=O)NCCN(CCO)CC([O-])=O HVFAVOFILADWEZ-UHFFFAOYSA-M 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000009044 synergistic interaction Effects 0.000 description 1
- 229940104261 taurate Drugs 0.000 description 1
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 1
- 238000000870 ultraviolet spectroscopy Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- OWVLYQRCCIEOPF-QHTZZOMLSA-L zinc;(2s)-5-oxopyrrolidine-2-carboxylate Chemical group [Zn+2].[O-]C(=O)[C@@H]1CCC(=O)N1.[O-]C(=O)[C@@H]1CCC(=O)N1 OWVLYQRCCIEOPF-QHTZZOMLSA-L 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Cosmetics (AREA)
Abstract
The invention belongs to the technical field of daily chemical articles, and discloses a composition with an anti-aging effect on scalp, a preparation method and application thereof. The composition with the scalp anti-aging effect comprises a bamboo leaf extract of the bear's head, a secondary fission yeast fermentation product filtrate, allantoin and panthenol. The composition takes the secondary fission yeast fermentation product filtrate as a solvent, utilizes the excellent permeability of micromolecular panthenol to enhance the oxidation resistance of the bamboo leaf extract of the giant knot weed, is favorable for improving the scavenging effect of the bamboo leaf extract of the giant knot weed on superoxide radical, and simultaneously, the unique softening effect of the amphoteric compound allantoin on skin can promote all components to better act on scalp, so that the composition can efficiently scavenge excessive superoxide radical in scalp, slow down the oxidation process of scalp and delay the aging of scalp.
Description
Technical Field
The invention belongs to the technical field of daily chemical articles, and particularly relates to a composition with an anti-aging effect on scalp, and a preparation method and application thereof.
Background
The thickness of the skin of the scalp is thinner than that of the skin of most parts of the face, the number of sebaceous glands of the scalp is large, sebum secretion is vigorous, the density of hair follicles of the scalp is high, and the content of free radicals is also high. With the increase of age, the function of the antioxidant system of the human body is declined, the activity of antioxidant enzyme is continuously reduced, free radicals are excessively accumulated, and the death of scalp cells is accelerated, so that the aging speed of the scalp is higher compared with the skin of other parts of the human body.
A radical is an atom or group with an unpaired electron. In the human body life activity, oxygen required by human body cell activity is removed, and the residual 2% of oxygen is converted into oxygen free radicals, wherein the superoxide free radicals belong to high-activity substances in the oxygen free radicals, and the aging of scalp is greatly accelerated due to the large accumulation of the superoxide free radicals, so that the problems about scalp and hair such as baldness, oil head and the like are further developed.
At present, people have certain consciousness and cognition on facial skin problems such as aging resistance, but the consciousness on scalp oxidation resistance and aging resistance is weak, and many products in the market generally pay attention to the effect that consumers can objectively sense the scalp skin problems such as dandruff removal, itching relieving, oil control, moisture retention, alopecia prevention and the like, neglect the problem that the scalp needs to remove redundant superoxide radical and resist scalp aging; and the scalp is more sensitive and thinner than the skin of other parts, so that the scalp is more difficult to resist aging than the skin of other parts.
Disclosure of Invention
The present invention is directed to solving at least one of the problems of the prior art described above. Therefore, the invention provides a composition with scalp anti-aging effect, and the components in the composition play a synergistic interaction role, so that the composition can effectively remove excessive superoxide radical from the scalp and delay scalp aging.
In a first aspect of the invention, a composition is provided comprising a bamboo leaf extract of Phyllostachys virescens, a fermentation product filtrate of Saccharomyces bifidus, allantoin, and panthenol.
The efficacy of the components of the composition of the invention is as follows:
the extract of the bamboo leaves of the giant salamander mainly contains chemical components such as flavonoid, organic acid, saccharide, phenols and the like, and the contained flavonoid compound has certain antioxidant activity and free radical scavenging capacity; the secondary cracking yeast fermentation product filtrate contains abundant polysaccharides and polypeptide substances, and can better recover the oxidative damage of skin free radicals; allantoin is an amphoteric compound, can combine various substances to form a compound salt, can promote the growth of skin cells, soften stratum corneum protein and accelerate wound healing, and is widely applied to the field of medicines; panthenol is one of important components of energy metabolism, has three hydroxyl structures, is soluble in water at room temperature, has a small molecular weight, and can permeate skin and hair.
The composition is prepared by combining the bamboo leaf extract of the panda vittata, the secondary fission yeast fermentation product filtrate, allantoin and panthenol, plays a role in synergy, is beneficial to improving the scavenging effect of the bamboo leaf extract of the panda vittata on superoxide radical, and simultaneously strengthens the barrier function of the scalp.
Preferably, the composition comprises, by weight, 0.5-16 parts of a bamboo leaf extract of bear's wort, 1-20 parts of a fermentation product filtrate of saccharomyces cerevisiae, 0.05-6 parts of allantoin and 0.05-20 parts of panthenol.
Preferably, the composition comprises 8-16 parts of the extract of the bamboo leaves of the bear plant, 10-20 parts of the secondary cracking yeast fermentation product filtrate, 3-6 parts of allantoin and 10-20 parts of panthenol by weight.
A second aspect of the invention provides a process for the preparation of a composition according to the invention, comprising the steps of:
mixing the extract of the bamboo leaves of the bear plant, the filtrate of the fermentation product of the saccharomyces cerevisiae, the allantoin and the panthenol, and stirring uniformly to obtain the composition.
In a third aspect the present invention provides the use of a composition according to the invention for the preparation of a cosmetic product.
Preferably, the composition is added in an amount of 0.1 to 10wt%.
Preferably, the composition is added in an amount of 3 to 10wt%.
Preferably, the cosmetic is in a form selected from a cream, lotion, aqua or gel.
Based on the application, the invention also provides shampoo which comprises the composition.
Preferably, the composition is added in an amount of 0.1-10wt% in the shampoo.
Preferably, the shampoo further comprises at least one of a surfactant, a preservative, a perfume, a conditioner and a chelating agent.
Based on the application, the invention also provides a hair conditioner comprising the composition.
Preferably, the composition is added to the hair conditioner in an amount of 0.1 to 10wt%.
Preferably, the hair conditioner further comprises at least one of a preservative, a perfume, a conditioner and a chelating agent.
Compared with the prior art, the invention has the following beneficial effects:
the composition with the scalp anti-aging effect comprises a bamboo leaf extract of the panda vittata, a secondary fission yeast fermentation product filtrate, allantoin and panthenol, the components play a synergistic role, the secondary fission yeast fermentation product filtrate is used as a solvent, the superior permeability of micromolecule panthenol is utilized, the antioxidant capacity of the bamboo leaf extract of the panda vittata is enhanced, the removal effect of the bamboo leaf extract of the panda vittata on superoxide radical is favorably improved, and meanwhile, the unique softening effect of the amphoteric compound allantoin on skin can promote each component to better act on the scalp, so that the composition can efficiently remove the excessive superoxide radical in the scalp, slow down the oxidation process of the scalp and delay the aging of the scalp.
Detailed Description
In order to make the technical solutions of the present invention more apparent to those skilled in the art, the following examples are given for illustration. It should be noted that the following examples are not intended to limit the scope of the claimed invention.
The raw materials, reagents, and apparatuses used in the following examples are all conventionally commercially available, unless otherwise specified, or may be obtained by conventionally known methods.
In the following examples, comparative examples:
the extract of the bamboo leaves of the bear's panda is purchased from Guangzhou Norgnonia Biotech limited;
the secondary split yeast fermentation product filtrate is purchased from Guangzhou bignonia biotechnologies GmbH;
allantoin was purchased from clarien chemical technology (shanghai) ltd;
panthenol is available from Dekkaido chemical Co., ltd.
Example 1
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
16% of a bamboo leaf extract of the giant napier, 10% of a secondary fission yeast fermentation product filtrate, 3% of allantoin, 10% of panthenol and the balance of water.
The preparation method of the composition with the scalp anti-aging effect comprises the following steps:
adding a proper amount of water into a pot; adding panthenol into the secondary cracking yeast fermentation product filtrate, dispersing uniformly, adding into a pot, heating to 50 ℃, and stirring for dissolving;
dispersing allantoin in the extract of folium Bambusae in Viburni, heating to 50 deg.C, adding into a pan, stirring for 10min while maintaining the temperature, and cooling to 30 deg.C to obtain composition with scalp antiaging effect.
Example 2
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
8% of a bamboo leaf extract of the bear plant, 10% of a secondary cracking yeast fermentation product filtrate, 3% of allantoin, 10% of panthenol and the balance of water.
The composition having scalp anti-aging effect of this example was prepared in the same manner as in example 1.
Example 3
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
0.5% of the extract of the bamboo leaves of the giant napier, 10% of the filtrate of the fermentation product of the second split yeast, 3% of allantoin, 10% of panthenol and the balance of water. The composition having scalp anti-aging effect of this example was prepared in the same manner as in example 1.
Example 4
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
8% of a bamboo leaf extract of the giant napier, 20% of a secondary fission yeast fermentation product filtrate, 3% of allantoin, 10% of panthenol and the balance of water. The composition having scalp anti-aging effect of this example was prepared in the same manner as in example 1.
Example 5
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
8% of a bamboo leaf extract of the giant napier, 1% of a secondary fission yeast fermentation product filtrate, 3% of allantoin, 10% of panthenol and the balance of water. The composition having scalp anti-aging effect of this example was prepared in the same manner as in example 1.
Example 6
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
8% of a bamboo leaf extract of the bear plant, 10% of a secondary cracking yeast fermentation product filtrate, 6% of allantoin, 10% of panthenol and the balance of water. The composition having scalp anti-aging effect of this example was prepared in the same manner as in example 1.
Example 7
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
8% of a bamboo leaf extract of the giant napier, 10% of a secondary fission yeast fermentation product filtrate, 0.05% of allantoin, 10% of panthenol and the balance of water. The composition having scalp anti-aging effect of this example was prepared in the same manner as in example 1.
Example 8
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
8% of a bamboo leaf extract of the bear plant, 10% of a secondary cracking yeast fermentation product filtrate, 3% of allantoin, 20% of panthenol and the balance of water. The composition having scalp anti-aging effect of this example was prepared in the same manner as in example 1.
Example 9
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
8% of a bamboo leaf extract of the giant napier, 10% of a secondary fission yeast fermentation product filtrate, 3% of allantoin, 0.05% of panthenol and the balance of water.
The composition having scalp anti-aging effect of this example was prepared in the same manner as in example 1.
Comparative example 1
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
16% of the extract of the bamboo leaves of the bear in Vildahl and the balance of water.
The preparation method of the composition with the scalp anti-aging effect of the comparative example comprises the following steps:
mixing the extract with water, and dispersing.
Comparative example 2
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
10% of secondary split yeast fermentation product filtrate and the balance of water.
The comparative example was the same as comparative example 1 in the preparation of the composition having scalp anti-aging effect.
Comparative example 3
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
allantoin 3% and water in balance.
The comparative example was the same as comparative example 1 in the preparation of the composition having scalp anti-aging effect.
Comparative example 4
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
panthenol 10% and water the rest.
The comparative example was the same as comparative example 1 in the preparation of the composition having scalp anti-aging effect.
Comparative example 5
The composition with the scalp anti-aging effect comprises the following components in percentage by mass:
16% of lophatherum gracile extract and the balance of water.
The comparative example was the same as comparative example 1 in the preparation of the composition having scalp anti-aging effect.
Comparative example 6
Comparative example 6 is different from example 1 in that comparative example 6 does not contain the extract of the leaves of Sasa Veitchii Rehder, and other components, amounts and preparation methods are the same as example 1.
The composition with the scalp anti-aging effect in the comparative example 6 comprises the following components in percentage by mass:
10% of secondary cracking yeast fermentation product filtrate, 3% of allantoin, 10% of panthenol and the balance of water.
Comparative example 7
Comparative example 7 is different from example 1 in that comparative example 7 does not contain the fermentation product filtrate of the yeast schizophyllum commune, and other components, amounts and preparation methods are the same as example 1.
The composition with the scalp anti-aging effect in the comparative example 7 comprises the following components in percentage by mass:
16% of a bamboo leaf extract of the giant knotweed, 3% of allantoin, 10% of panthenol and the balance of water.
Comparative example 8
Comparative example 8 differs from example 1 in that comparative example 8 does not contain allantoin, and the other components, amounts, and preparation methods are the same as in example 1.
The composition with the scalp anti-aging effect in the comparative example 8 comprises the following components in percentage by mass:
16% of a bamboo leaf extract of the bear plant, 10% of a secondary cracking yeast fermentation product filtrate, 10% of panthenol and the balance of water.
Comparative example 9
Comparative example 9 differs from example 1 in that comparative example 9 does not contain panthenol and the other components, amounts and preparation methods are the same as example 1.
The composition with the scalp anti-aging effect in the comparative example 9 comprises the following components in percentage by mass:
16% of a bamboo leaf extract of the giant napier, 10% of a secondary fission yeast fermentation product filtrate, 3% of allantoin and the balance of water.
Comparative example 10
Comparative example 10 is different from example 1 in that in comparative example 10, the extract of the leaf of Sasa Veitchii Rehder is replaced with the extract of the leaf of Phyllostachys Pubescens of similar efficacy, and the other components, the amounts and the preparation method are the same as those in example 1.
The composition with the scalp anti-aging effect in the comparative example 10 comprises the following components in percentage by mass:
16% of lophatherum gracile extract, 10% of secondary fission yeast fermentation product filtrate, 3% of allantoin, 10% of panthenol and the balance of water.
Comparative example 11
Comparative example 11 is different from example 1 in that the secondary split yeast fermentation product filtrate is replaced by the galactoyeast fermentation product filtrate with similar efficacy in comparative example 11, and other components, amounts and preparation methods are the same as example 1.
The composition with the scalp anti-aging effect in the comparative example 11 comprises the following components in percentage by mass:
16% of a bamboo leaf extract of the bear plant, 10% of a galactose yeast-like bacteria fermentation product filtrate, 3% of allantoin, 10% of panthenol and the balance of water.
Comparative example 12
Comparative example 12 differs from example 1 in that allantoin was replaced with zinc PCA of similar efficacy in comparative example 12, and the other components, amounts and preparation methods were the same as in example 1.
The composition with the scalp anti-aging effect in the comparative example 12 comprises the following components in percentage by mass:
16% of a bamboo leaf extract of the bear's disease, 10% of a secondary cracking yeast fermentation product filtrate, 3% of PCA zinc, 10% of panthenol and the balance of water.
Comparative example 13
Comparative example 13 is different from example 1 in that panthenol in comparative example 13 is replaced with sodium hyaluronate of similar efficacy, and other components, amounts and preparation methods are the same as example 1.
The composition with the scalp anti-aging effect in the comparative example 13 comprises the following components in percentage by mass:
16% of a bamboo leaf extract of the giant napier, 10% of a secondary fission yeast fermentation product filtrate, 3% of allantoin, 10% of sodium hyaluronate and the balance of water.
Test example 1
Superoxide radical (O) 2 - ) Cleaning test of
The test method comprises the following steps: determination of autoxidation Rate by terminator method.
Reagent: except Tris (hydroxymethyl) aminomethane (Tris) as import, other reagents are domestic analytical pure or domestic biochemical reagents (preparation water is secondary distilled water).
The instrument comprises the following steps: UV-754 type ultraviolet-visible spectrophotometer (Shanghai third analytical instrument factory), and super constant temperature water bath (Shanghai laboratory instrument factory).
Sample preparation: example 1, example 2, example 3, example 4, example 5, example 6, example 7, example 8, example 9, comparative example 1, comparative example 2, comparative example 3, comparative example 4, comparative example 5, comparative example 6, comparative example 7, comparative example 8, comparative example 9, comparative example 10, comparative example 11, comparative example 12, comparative example 13 were each diluted with double distilled water to 10wt% aqueous solutions.
The test contents are as follows: the total volume of 3mL of the reaction solution contained the following reagents (in final concentrations): tris-HCI buffer, pH =8.20, 50mmol; 1mmol of diethylenetriaminepentaacetic acid; 0.2mmol of pyrogallol; samples to be tested with different concentrations. The reaction was carried out in a thermostatic water bath at 25 ℃ and was initiated by the addition of pyrogallol dissolved in 10mmol HCI and preheated at 25 ℃ for 5min, and the reaction was stopped by the addition of 30. Mu.L of 100mmol DL-Dimercaptothreitol (DTT) and the absorbance value (A) at 325nm was recorded over 1 h.
The following formula calculates each sample pair O 2 - Clearance (I%): i% = [1- (A3-A4)/(A1-A2)]×100；
A1: absorbance value without sample;
a2: absorbance values without sample and pyrogallol;
a3: an absorbance value comprising the sample;
a4: absorbance values with sample, but no pyrogallol. The test results are shown in table 1.
TABLE 1
As can be seen from the data in table 1, comparative examples 1-4 resulted in a significant reduction in clearance due to the use of a single efficacy component compared to example 1; according to the data of comparative examples 1-4, the extract of the leaf of Sasa Veitchii Rehder was found to be O 2 - The cleaning plays a main role; meanwhile, according to the data of comparative examples 7-9, compared with example 1, the comparative examples 7-9 have obviously reduced clearance rate due to the lack of the secondary fission yeast fermentation product filtrate, allantoin and panthenol respectively, which shows that the simultaneous addition of the secondary fission yeast fermentation product filtrate, allantoin and panthenol can obviously improve the O content of the Phyllostachys Victoria leaf extract on O 2 - The clearance rate of (c); according to the data of comparative examples 1 and 5, the extract of the leaf of Sasa Veitchii Rehder and the extract of Phyllostachys Pubescens can be compared with O 2 - The effect of the clearance rate is equivalent, while the clearance rate is obviously reduced in the comparative example 10 because the extract of the bamboo leaves of the bear plant of the Viburni is replaced by the extract of the bamboo leaves of the Bombarus calamus, and the data of the comparative examples 11-13 are combined, the comparative examples 11-13 have similar effects because the filtrate of the fermentation product of the yeast of the fission, allantoin and panthenol are respectively replaced by the filtrate of the fermentation product of the yeast of the fission, allantoin and panthenolThe galactose yeast-like bacteria fermentation product filtrate, the PCA zinc and the sodium hyaluronate all cause the clearance rate to be obviously reduced, so that the bamboo leaf extract of the Ursus vilmorio, the secondary fission yeast fermentation product filtrate, the allantoin and the panthenol in the composition can play a synergistic role and can effectively clear O 2 - 。
Application example 1
Application example 1 provides a shampoo, and the formulation of the shampoo is shown in table 2.
TABLE 2
The preparation method of the shampoo in application example 1 comprises the following steps:
(1) adding guar hydroxypropyl trimethyl ammonium chloride and water into an emulsifying pot, homogenizing and stirring, adding cocoamidopropyl betaine and sodium cocoyl methyl taurine taurate after uniform dispersion, uniformly dispersing, starting to heat, and heating to 80 ℃;
(2) adding sodium lauroamphoacetate, decyl glucoside, sodium cocoamidopropionate, disodium EDTA, sodium benzoate, cetyl alcohol and cocamidomethyl MEA, stirring, and holding for 30min;
(3) cooling to 45 ℃, adding the polyquaternium-7 and the composition obtained in the example 1, and uniformly stirring;
(4) adding essence and phenoxyethanol, and regulating pH to 5.5-6.8 with citric acid;
(5) cooling to 37 ℃, filtering by 200 meshes and discharging.
Application comparative example 1
Application comparative example 1 is different from application example 1 in that application comparative example 1 does not contain the composition obtained in example 1, and other components, amounts and preparation methods are the same as application example 1.
Test example 2
Scalp anti-aging test
The test method comprises the following steps: the test part is the head, 30 subjects adopt a half-head test method for 2 months, the using amount of each time keeps the same specification of packing materials, the same pump number is used on the left and the right according to the actual requirements of the subjects, the shampoo of the application example 1 is used on the left, and the shampoo of the application example 1 is used on the right.
The subject claims: 30-55 years old, dry, oily and neutral scalp, and any cosmetics, medicines and health products which have influence on the result can not be used during the test period.
The using method comprises the following steps: fully wetting hair by clear water; applying appropriate amount of shampoo on both hands, rubbing out foam, placing on head, and gently kneading to generate foam without excessively rubbing hair for about 1 min; when in washing, the fingers are also used for gently stroking and straightening the hair and washing the hair cleanly.
The evaluation method comprises the following steps: the subjects evaluated (scalp firmness, hair follicle health) with a score of 1-10, with higher scores representing better corresponding efficacy. The results of the scalp firmness and hair follicle health scoring are shown in tables 3 and 4, respectively. Wherein scalp firmness is scored by the subject according to the perceived scalp firmness as a function of pressing on the hair covered portion of the area above the ears; the hair follicle health degree is graded by the condition that the scalp has common problems such as faster oil discharge, dryness, itching, redness, pimples and the like according to the existence of the scalp.
TABLE 3
As can be seen from the scoring results in tables 3 and 4, the shampoo containing the composition obtained in example 1 of the present invention was effective in reducing the aging of the scalp after two months of human body tests.
Test example 3
Red blood cell test assay
The test method comprises the following steps: the hemolysis test of erythrocytes was used to evaluate the mildness of example 1, example 2, example 3, example 4, example 5, example 6, example 7, example 8, example 9, application example 1, and application comparative example 1.
The test contents are as follows: the sample to be tested is diluted into 2mL with physiological saline respectively with the mass fractions of 0.1%, 0.2%, 0.3%, 0.5%, 1%, 2%, 10% and 20%. Mixing 500 μ L of prepared sample and 500 μ L of red blood cell with mass fraction of 2%, setting negative control (normal saline) and positive control (mass fraction of 1 SDS), setting 3 parallel in each group, standing in biochemical incubator at 37 deg.C, incubating for 3h, centrifuging each group of sample, mixing supernatant 10 μ L and normal saline 90 μ L in 96-well plate, and measuring absorbance at 410, 540 and 575 nm. The ratio (L/D) of the concentration of the test substance (HC 50) to the denaturation rate of hemoglobin (DI) which caused hemolysis of 50% of erythrocytes was calculated by taking the average value of each group. (L/D >100: no irritation; 10-woven cloth L/D < 100: micro irritation; 1<L/D < 10: mild irritation; 0.1-woven cloth L/D < 1: moderate irritation; L/D < 0.1: severe irritation). The test results are shown in table 5.
TABLE 5
As can be seen from Table 5, the addition of the composition of the present invention to shampoo did not bring about a significant improvement in the irritativeness, and the composition of the present invention hardly affected the irritativeness of the added system.
The results show that on one hand, the composition with the scalp anti-aging effect, which consists of the extract of the bamboo leaves of the bear plant, the secondary fission yeast fermentation product filtrate, the allantoin and the panthenol, can play a synergistic effect to effectively remove excessive superoxide radical in the scalp; on the other hand, the product added with the composition with scalp anti-aging effect can effectively slow down the scalp aging, and the composition with scalp anti-aging effect does not aggravate the irritation of the product added with the system.
While the preferred embodiments of the present invention have been illustrated and described, it will be understood by those skilled in the art that the present invention is not limited to the details of the embodiments shown and described, but is capable of numerous equivalents and substitutions without departing from the spirit of the invention as set forth in the claims appended hereto.
Claims (10)
1. A composition comprises a Phyllostachys virginiana leaf extract, a fermentation product filtrate of Saccharomyces cerevisiae, allantoin, and panthenol.
2. The composition as claimed in claim 1, which comprises 0.5-16 parts by weight of the extract of the leaf of Sasa Veitchii Rehder, 1-20 parts by weight of the filtrate of the fermentation product of the yeast schizophyllum commune, 0.05-6 parts by weight of allantoin and 0.05-20 parts by weight of panthenol.
3. The composition as claimed in claim 2, which comprises 8-16 parts by weight of the extract of the bamboo leaves of the bear plant, 10-20 parts by weight of the filtrate of the fermentation product of the yeast schizophyllum, 3-6 parts by weight of allantoin and 10-20 parts by weight of panthenol.
4. A process for the preparation of a composition according to any one of claims 1 to 3, characterized in that it comprises the following steps:
mixing the extract of the bamboo leaves of the bear plant, the filtrate of the fermentation product of the saccharomyces cerevisiae, the allantoin and the panthenol, and stirring uniformly to obtain the composition.
5. Use of a composition according to any one of claims 1 to 3 for the preparation of a cosmetic product.
6. Use according to claim 5, wherein the composition is added in an amount of 0.1 to 10wt%.
7. Use according to claim 6, wherein the composition is added in an amount of 3 to 10wt%.
8. Use according to claim 5, characterized in that the cosmetic formulation is selected from a cream, an emulsion, an aqua or a gel.
9. A shampoo comprising the composition of any of claims 1 to 3.
10. A hair conditioner comprising the composition of any one of claims 1 to 3.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211548359.3A CN115887338B (en) | 2022-12-05 | 2022-12-05 | Composition with scalp anti-aging effect and preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211548359.3A CN115887338B (en) | 2022-12-05 | 2022-12-05 | Composition with scalp anti-aging effect and preparation method and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115887338A true CN115887338A (en) | 2023-04-04 |
| CN115887338B CN115887338B (en) | 2024-02-23 |
Family
ID=86493599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211548359.3A Active CN115887338B (en) | 2022-12-05 | 2022-12-05 | Composition with scalp anti-aging effect and preparation method and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115887338B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113304065A (en) * | 2021-05-08 | 2021-08-27 | 广州宝思利生物科技有限公司 | Scalp care composition and application thereof |
| CN113350204A (en) * | 2021-06-08 | 2021-09-07 | 诺斯贝尔化妆品股份有限公司 | Physical and chemical combined oil-controlling and soothing shaking toner and preparation method thereof |
| CN113456569A (en) * | 2021-07-08 | 2021-10-01 | 安婕妤化妆品科技股份有限公司 | Skin elastic repairing and moisturizing mask and preparation method thereof |
| CN114796031A (en) * | 2022-04-02 | 2022-07-29 | 广州环亚化妆品科技股份有限公司 | Composition for scalp care and preparation method and application thereof |
-
2022
- 2022-12-05 CN CN202211548359.3A patent/CN115887338B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113304065A (en) * | 2021-05-08 | 2021-08-27 | 广州宝思利生物科技有限公司 | Scalp care composition and application thereof |
| CN113350204A (en) * | 2021-06-08 | 2021-09-07 | 诺斯贝尔化妆品股份有限公司 | Physical and chemical combined oil-controlling and soothing shaking toner and preparation method thereof |
| CN113456569A (en) * | 2021-07-08 | 2021-10-01 | 安婕妤化妆品科技股份有限公司 | Skin elastic repairing and moisturizing mask and preparation method thereof |
| CN114796031A (en) * | 2022-04-02 | 2022-07-29 | 广州环亚化妆品科技股份有限公司 | Composition for scalp care and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 佚名: "Su:m37 Flawless Regenerating Lotion", Retrieved from the Internet <URL:http://www.cosdna.com/chs/cosmetic_830431173.html> * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN115887338B (en) | 2024-02-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108379140B (en) | Composition with whitening and anti-aging functions and preparation method thereof | |
| CN106038330B (en) | A kind of mildy wash and preparation method thereof | |
| CN109350591B (en) | Dry facial mask for beautifying face and preparation method thereof | |
| CN111265439A (en) | Oil-control, dandruff-removing and itching-relieving shampoo and preparation method thereof | |
| CN107982135A (en) | A kind of shampoo and preparation method thereof | |
| CN112168766A (en) | Anti-inflammatory and relieving aloe gel and preparation method thereof | |
| CN114796024B (en) | Bionic sebum composition for skin barrier repair, and preparation method and application thereof | |
| CN107411998B (en) | Antioxidant mask containing active peptide of hairtail | |
| CN110368337B (en) | Facial mask containing rose hip extract and preparation method | |
| CN106619379A (en) | Composition containing plant fermentation product as well as preparation method and application of composition | |
| CN104188859B (en) | A kind of crease-resistant skin care emulsion containing natural component extract and preparation method thereof | |
| CN109381375B (en) | Essential oil composition for scalp care and application | |
| CN109846967B (en) | Traditional Chinese medicine composition with antibacterial, itching-relieving and antioxidant effects | |
| CN117017881A (en) | Composition for improving bioavailability of rare ginsenoside, preparation method and application | |
| CN115444766B (en) | Bi-component shampoo with scalp nourishing effect and preparation method thereof | |
| CN115887338B (en) | Composition with scalp anti-aging effect and preparation method and application thereof | |
| CN113081924B (en) | Antioxidant composition, preparation method and application | |
| CN115429738A (en) | Acne-removing repairing revitalizing essence and preparation method thereof | |
| KR20170010499A (en) | Cosmetic Compositions comprising Snail mucus fermentation filtrate for improving skin barrier function and having high skin absorption and Functional Cosmetic using this | |
| TWI809308B (en) | Use of wasabia japonica leaves for inhibiting the production of acne and reducing cutibacterium acnes secretions | |
| CN111979289B (en) | Cytological evaluation method for plant extract resisting skin chemical stimulus and application thereof | |
| CN110025515B (en) | Anti-allergy polysaccharide compound composition and application thereof in cosmetics | |
| TWI674107B (en) | Use of imperata cylindrica fermented extract for enhancing the gene expression of keratin, filaggrin and hyaluronan synthase, promoting the proliferation of collagen and elastin, and enhancing antioxidant capacity of skin cells | |
| CN108888573B (en) | Soothing and moisturizing cream and preparation method thereof | |
| JPH03167113A (en) | Hair regenerating agent |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |