CN115399476A - 一种具有辅助润肠通便功能的食品组合物 - Google Patents
一种具有辅助润肠通便功能的食品组合物 Download PDFInfo
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- CN115399476A CN115399476A CN202110595964.5A CN202110595964A CN115399476A CN 115399476 A CN115399476 A CN 115399476A CN 202110595964 A CN202110595964 A CN 202110595964A CN 115399476 A CN115399476 A CN 115399476A
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Abstract
本发明涉及一种具有辅助润肠通便功能的食品组合物。本发明属于保健食品技术领域，具体涉及一种辅助改善便秘和肠道菌群功能的食品组合物及其制备方法和用途。该食品组合物包括以下重量份的组分：菊粉20‑40份，低聚木糖4‑8份，白芸豆4‑8份，茯苓3‑6份，薏苡仁4‑6份，膳食纤维粉10‑20份，魔芋粉1‑3份，沙棘1‑2份，库拉索芦荟1‑3份，葛根1‑2份，黑芝麻1‑2份，玉竹1‑2份，山药1‑2份。本发明中的食品组合物，在各组分剂量范围内均能产生改善便秘和肠道菌群的功效，同时其生产工艺简单，适合产业化。
Description
技术领域
本发明属于保健食品，具体涉及一种具有辅助润肠通便功能的食品组合物。
背景技术
随着人们生活水平的提高，饮食结构的改变及精神心理社会因素的影响，便秘已经严重影响了现代人生活质量。且在结肠癌、肝性脑病、乳腺疾病、早老性痴呆等疾病的发生有重要作用；在急性心肌梗死、脑血管疾病等时，便秘可导致生命意外。便秘是一种常见的消化系统疾病，在多种致病因素作用下，结直肠、肛门的结构和功能发生改变，临床出现以排便困难或排便量少或不排便及其伴随的相关不适为主要表现的一类疾病。便秘已经成为困扰全球的一大问题。目前，美国和欧洲的便秘发病率最高，达到14%～30%; 老年人和患有各种疾病患者的便秘发病率更高。我国慢性便秘患者占普通人群的3%-17.6%，年纪越大便秘患者越多，其中女性慢性便秘患病率比男性高。据估算，中国约有超过7000万的女性饱受慢性便秘带来的困扰。
近年来，研究表明肠道菌群与便秘具有紧密联系。肠道菌群占机体微生物总量的78.67%，是机体微生态系统最重要的组成部分。研究发现成年便秘患者肠道中的乳杆菌和双歧杆菌显著降低。便秘性的肠易激综合征患者表现出肠杆菌科细菌的显著增加，而双歧杆菌、乳杆菌、柔嫩梭菌和普氏栖粪杆菌的数量显著降低。
目前临床常用治疗便秘的药物有容积性泻剂、渗透性泻剂、润滑性泻剂、刺激性泻剂和促动力剂，这些药物虽然有较好的治疗便秘的作用，但是不适宜长时间使用，引起水电解质紊乱，影响脂溶性维生素及钙、磷的吸收以及结肠黑病变等。通过调节肠道菌群结构和平衡改善便秘，具有疗效好，毒副作用小的优点，而具有广阔的开发和应用前景。
发明内容
1、本发明的目的在于提供一种具有辅助润肠通便功能的食品组合物及其制备方法。制备工艺简单，疗效好，安全无副作用。
2、本发明的上述目的是通过以下技术方案予以实现的：
一种具有润肠通便功效的食品组合物，该食品组合物包括如下重量分数的组分：菊粉20-40份，低聚果糖20-40份，低聚木糖4-8，白芸豆4-8份，茯苓3-6份，薏苡仁4-6份，膳食纤维粉5-15份，魔芋粉1-3份，沙棘1-2份，库拉索芦荟1-3份，葛根1-2份，黑芝麻1-2份，玉竹1-2份，山药1-2份。
其中，各组分的质量份优选如下：
（1）组方1：菊粉30份，低聚果糖25份，膳食纤维粉8份，低聚木糖6份，白芸豆6份，茯苓4份，薏苡仁4份，魔芋粉2份，沙棘2份，库拉索芦荟2份，葛根1份，黑芝麻1份，玉竹2份，山药2份。
（2）组方2：菊粉24份，低聚果糖20份，膳食纤维粉12份，低聚木糖6份，白芸豆4份，茯苓3份，薏苡仁3份，魔芋粉3份，沙棘2份，库拉索芦荟3份，葛根2份，黑芝麻2份，玉竹2份，山药2份。
（3）组方3：菊粉20份，低聚果糖20份，膳食纤维粉10份，低聚木糖4份，白芸豆3份，茯苓3份，薏苡仁3份，魔芋粉2份，沙棘2份，库拉索芦荟2份，葛根1份，黑芝麻1份，玉竹1份，山药1份。
3、所述辅助润肠通便的食品组合物作为制备辅助治便秘，改善肠道菌群的保健食品中的用途。本发明可以加入辅料制成不同的剂型，包括粉剂，口服液，半固体制剂，片剂，胶囊剂，散剂，颗粒剂，冲剂，泡腾剂或袋泡剂等，所用的辅料为一般药学上可接受的辅料。
4、本发明提供了一种具有润肠通便功能的食品组合物的制备方法，该制备方法包括如下步骤：准确称取相应的原料和药材，将所用药材用清水进行清洗，800℃、1小时进行蒸熟，65℃恒温烘箱烘干，粉碎机打粉，过120目筛子，将原料和药材粉末混匀后制成所需的剂型。
5、本发明各组分功效如下：
（1）菊粉，天然的水溶性膳食纤维，在结肠被有益微生物利用，从而改善肠道环境。菊粉可以保持肠道内水分不被过分吸收, 增加排便次数和质量, 对便秘有显著的改善作用。摄入菊粉后能增强胃肠道蠕动，提高肠胃功能，增加消化和食欲，提高机体免疫力。
（2）膳食纤维粉，是一种多糖，可以促进胃肠道蠕动，加快食物通过胃肠道，减少吸收，另外不可溶性纤维在大肠中吸收水分软化大便，可以起到防治便秘的作用。
（3）低聚果糖，又称寡果糖或蔗糖三糖族低聚糖，可以通过选择性促进乳酸杆菌、双歧杆菌和链球菌等有益菌在消化道中的定植，抑制有害细菌生长，改善肠道菌群；促进B族维生素及叶酸的形成，能维护神经系统的正常功能，促进消化及新陈代谢；清肠排毒、润肠通便、防治便秘和痔疮；预防直肠和结肠癌；减少肝脏毒素，增强人体免疫力。
（4）低聚木糖，又称木寡糖，是聚合糖类中增殖双歧杆菌功能最强的品种之一，它的功效性是其他聚合糖类的近20倍，人体胃肠道内没有水解低聚木糖的酶，所以其可直接进入大肠内优先为双歧杆菌所利用，双歧杆菌利用低聚木糖，产生大量的短链脂肪酸；能刺激肠道蠕动，增加粪便湿润度，并保持一定的渗透压，从而防止便秘发生。
（5）白芸豆，性味甘、平, 具有温中下气、利肠胃、止呃逆、益肾补元等功用, 是一种滋补食疗佳品。芸豆还有镇静作用, 对治疗虚寒呃逆、胃寒呕吐、跌打损伤、喘息咳嗽、腰痛、神经痛均有一定疗效。所含的膳食纤维加快食物通过肠道的时间，所含淀粉酶抑制剂可以阻断食入人体食物中淀粉的水解，减少人体内脂肪的生成。
（6）茯苓，甘、淡，平。归心、肺、脾、肾经。利水渗湿，健脾宁心。用于水肿尿少，痰饮眩悸，脾虚食少，便溏泄泻，心神不安，惊悸失眠，利水渗湿，健脾化痰，宁心安神；补脾，运化营养物质入血，补血不足，助消化；运化水液，消除痰湿之邪，性平寒热均可。
（7）薏苡仁，味甘、淡，性凉。归脾、胃、肺经。利水渗透湿，健脾止泻，除痹，排脓，解毒散结。用于水肿，脚气，小便不利，脾虚泄泻，湿痹拘挛，肺痈，肠痈；赘疣，癌肿。
（8）魔芋粉，含有多种维生素和钾、磷、硒等矿物质元素，还含有魔芋多糖，并具有低热量、低脂肪和高纤维素的特点。活血化瘀、润肠通便、减少对脂肪的吸收、充饥减肥。
（9）沙棘，酸、涩，温。归脾、胃、肺、心经。健脾消食，止咳祛痰，活血散瘀。用于脾虚食少，食积腹痛，咳嗽痰多，胸痹心痛，瘀血经闭，跌扑瘀胂。
（10）库拉索芦荟，性寒、味苦,归肝、胃、大肠经,具有杀菌抗炎,清肝泻火,健胃下泄,强心活血,解毒化瘀,杀虫疗疳,免疫和再生作用。它是一种天然的通便剂, 能促进大肠蠕动而对小肠无副作用。
（11）黑芝麻，性平，味甘。补肝肾，益精血，润肠燥。用于头晕眼花、耳鸣耳聋、须发早白、病后脱发、肠燥便秘。
（12）玉竹，甘，微寒。归肺、胃经。养阴润燥，生津止渴。用于肺胃阴伤，燥热咳嗽，咽干口渴，内热消渴。
（13）山药，甘，平。归脾、肺、肾经。补脾养胃，生津益肺，补肾涩精。用于脾虚食少，久泻不止，肺虚喘咳，肾虚遗精，带下，尿频，虚热消渴。
上述13种天然植物原料组分协同作用，可发挥辅助改善便秘的作用。
6、本发明与现有技术相比，具有如下优点：
本发明涉及的食品组合物由膳食纤维，益生元和食药同源药材组成，膳食纤维可以促进胃肠道蠕动，增加排便次数和质量；益生元可以刺激有益菌的生长，促进双歧杆菌的增殖，从而达到使益生菌成为肠道优势菌种，排除有害菌的目的。食药同源中药材中茯苓、薏苡仁具有利水渗透湿，健脾止泻功效，沙棘、黑芝麻具有活血散瘀、补肝肾，益精血，润肠燥功效，玉竹、山药具有养阴润燥、生津益肺功效，上述膳食纤维，益生元和食药同源药材协同作用，可发挥辅助改善便秘的作用，安全无副作用，适合长期服用。
具体实施方式
以下通过实施例形式，对本发明的上述内容再作进一步的详细说明，但不应将此理解为本发明上述主题的范围仅限于以下的实例，凡基于本发明上述内容所实现的技术均属于本发明的范围。
实施例1：
一种具有润肠通便功效的食品组合物，由以下原料重量份数的组分组成：菊粉30份，低聚果糖25份，膳食纤维粉8份，低聚木糖6份，白芸豆6份，茯苓4份，薏苡仁4份，魔芋粉2份，沙棘2份，库拉索芦荟2份，葛根1份，黑芝麻1份，玉竹2份，山药2份。
实施例2：
一种具有润肠通便功效的食品组合物，由以下原料重量份数的组分组成：菊粉24份，低聚果糖20份，膳食纤维粉12份，低聚木糖6份，白芸豆4份，茯苓3份，薏苡仁3份，魔芋粉3份，沙棘2份，库拉索芦荟3份，葛根2份，黑芝麻2份，玉竹2份，山药2份。
实施例3：
一种具有润肠通便功效的食品组合物，由以下原料重量份数的组分组成：菊粉20份，低聚果糖20份，膳食纤维粉10份，低聚木糖4份，白芸豆3份，茯苓3份，薏苡仁3份，魔芋粉2份，沙棘2份，库拉索芦荟2份，葛根1份，黑芝麻1份，玉竹1份，山药1份。
应用实施例对本发明的效果进行检测。
实验方法：选择年龄在20-50岁之间，具有经常便秘症状的人群120人，临床表现为便秘、排便困难、粪质硬、排便不尽感、排便间隔时间长等症状，随机分为4组，每组30人
治疗方法：前三组分别每天上午，中午，下午分三次食用实施例1、实施例2、实施例3提供的食品组合物，第4组每天在相同时间段分别饮用100g纯净水，各组的其他饮食和社会环境均保持一致，作为对比。每组试验者可根据自己意愿进食，实验周期为两周；
疗效标准：显效：便秘、排便困难症状消失，大便每日，排便顺畅，且连续保持2周以上；有效：便秘、排便困难症状缓解，大便每周5次以上，但有时出现排便困难的情况；无效：便秘、排便困难症状未有好转。
对比各种试验者进行考察，考察结果如下表所示。
试验者的症状改善考察结果
从上表的考察结果可以看出，实施例1，实施例2、实施例3制备所得的润肠通便组合物均可有效改善调节试验者的便秘症状，总有效率为100%，显效率均在80%以上，其中效果最明显的是实施例2，食用本发明可用于改善便秘人群的实践。
以上所述，仅为本发明的较佳的具体实施案例，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，根据本发明的技术方案及其构思加以等同替换或改变，都应涵盖在本发明的保护范围内。
Claims (6)
1.一种改善便秘和肠道菌群的功能食品组合物，其特征在于，包括如下重量分数的组分：菊粉20-40份，低聚果糖20-40份，低聚木糖4-8，白芸豆4-8份，茯苓3-6份，薏苡仁4-6份，膳食纤维粉5-15份，魔芋粉1-3份，沙棘1-2份，库拉索芦荟1-3份，葛根1-2份，黑芝麻1-2份，玉竹1-2份，山药1-2份。
2.如权利要求 1 所述的一种改善便秘和肠道菌群的功能食品组合物，其特征在于，包括如下重量分数的组分：菊粉30份，低聚果糖25份，膳食纤维粉8份，低聚木糖6份，白芸豆6份，茯苓4份，薏苡仁4份，魔芋粉2份，沙棘2份，库拉索芦荟2份，葛根1份，黑芝麻1份，玉竹2份，山药2份。
3.如权利要求 1 所述的一种改善便秘和肠道菌群的功能食品组合物，其特征在于，包括如下重量分数的组分：菊粉24份，低聚果糖20份，膳食纤维粉12份，低聚木糖6份，白芸豆4份，茯苓3份，薏苡仁3份，魔芋粉3份，沙棘2份，库拉索芦荟3份，葛根2份，黑芝麻2份，玉竹2份，山药2份。
4.如权利要求 1 所述的一种改善便秘和肠道菌群的功能食品组合物，其特征在于，包括如下重量分数的组分：菊粉20份，低聚果糖20份，膳食纤维粉10份，低聚木糖4份，白芸豆3份，茯苓3份，薏苡仁3份，魔芋粉2份，沙棘2份，库拉索芦荟2份，葛根1份，黑芝麻1份，玉竹1份，山药1份。
5.一种改善便秘和肠道菌群的功能食品组合物的制备工艺，其特征在于，包括以下步骤：准确称取相应的原料和药材，将所用药材用清水进行清洗，800℃、1小时进行蒸熟，65℃恒温烘箱烘干，粉碎机打粉，过120目筛子，将原料和药材粉末混匀后制成所需的剂型。
6.如权利要求 1 所述的一种改善便秘和肠道菌群的功能食品组合物，其特征在于，本发明可以加入辅料制成不同的剂型，包括粉剂，口服液，半固体制剂，片剂，胶囊剂，散剂，颗粒剂，冲剂，泡腾剂或袋泡剂等，所用的辅料为一般药学上可接受的辅料。
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