CN115089790A - An extracorporeal circulation system for blood purification equipment and its automatic priming method - Google Patents

An extracorporeal circulation system for blood purification equipment and its automatic priming method Download PDF

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CN115089790A
CN115089790A CN202210580753.9A CN202210580753A CN115089790A CN 115089790 A CN115089790 A CN 115089790A CN 202210580753 A CN202210580753 A CN 202210580753A CN 115089790 A CN115089790 A CN 115089790A
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priming
dialysate
extracorporeal circulation
venous
blood
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高光勇
童锦
陈飞
李绍林
谢川
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Sws Hemodialysis Care Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3639—Blood pressure control, pressure transducers specially adapted therefor

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Abstract

本发明涉及血液净化技术领域,具体涉及一种血液净化设备体外循环系统及其自动预冲方法,所述血液净化设备体外循环系统包括透析器以及体外循环管路,所述透析器通过半透膜分隔为血液室和透析液室,并同时设有与所述血液室连通的血室上端接口和血室下端接口、与所述透析液室连通的透析液上端接口和透析液下端接口;所述体外循环管路包括静脉管路和动脉管路,所述动脉管路的一端连接至所述血室上端接口,所述静脉管路的一端连接至所述血室下端接口。可有效地解决现有技术中存在的问题,以最大限度的简化透析治疗准备的操作步骤,减少误操作的几率,并降低医护人员操作劳动强度。

Figure 202210580753

The invention relates to the technical field of blood purification, in particular to an extracorporeal circulation system of blood purification equipment and an automatic pre-priming method thereof. The extracorporeal circulation system of blood purification equipment includes a dialyzer and an extracorporeal circulation pipeline, and the dialyzer passes through a semipermeable membrane. It is divided into a blood chamber and a dialysate chamber, and is provided with an upper end port of the blood chamber and a lower end port of the blood chamber that communicate with the blood chamber, an upper end port of the dialysate and a lower end port of the dialysate communicated with the said dialysate chamber; The extracorporeal circulation pipeline includes a venous pipeline and an arterial pipeline, one end of the arterial pipeline is connected to the upper port of the blood chamber, and one end of the venous pipeline is connected to the lower port of the blood chamber. The problems existing in the prior art can be effectively solved, the operation steps of dialysis treatment preparation can be simplified to the greatest extent, the probability of misoperation can be reduced, and the operation labor intensity of medical staff can be reduced.

Figure 202210580753

Description

一种血液净化设备体外循环系统及其自动预冲方法An extracorporeal circulation system for blood purification equipment and its automatic priming method

技术领域technical field

本发明涉及血液净化技术领域,尤其涉及一种血液净化设备体外循环系统及其自动预冲方法。The present invention relates to the technical field of blood purification, in particular to an extracorporeal circulation system of blood purification equipment and an automatic priming method thereof.

背景技术Background technique

血液净化治疗用透析器是由多根空心纤维膜、外壳和端盖组成,空心纤维膜将透析器分割为两个室,其中,空心纤维膜内为血液室,空心纤维膜与外壳之间为透析液室。空心纤维膜为半透膜,膜上有无数个微小的孔,中小分子物质可以通过这些小孔,血细胞等大分子物质不能通过这些小孔。在血液净化治疗过程,通过将患者的动脉端血液引入经过上述的空心纤维膜组成的透析器,血液室内的血液与透析液室中的透析液在透析器内通过弥散/对流进行物质交换,清除患者血液中的代谢废物和体内过多的水分,并维持电解质和酸碱平衡,然后将净化了的血液再由静脉端回输体内,以达到体内血液净化目的。The dialyzer for blood purification treatment is composed of a plurality of hollow fiber membranes, a shell and an end cap. The hollow fiber membrane divides the dialyzer into two chambers. The inside of the hollow fiber membrane is the blood chamber, and the space between the hollow fiber membrane and the shell is Dialysate chamber. The hollow fiber membrane is a semi-permeable membrane, and there are countless tiny pores on the membrane. Small and medium molecules can pass through these pores, but macromolecular substances such as blood cells cannot pass through these pores. In the process of blood purification treatment, by introducing the patient's arterial blood into the dialyzer composed of the above-mentioned hollow fiber membranes, the blood in the blood chamber and the dialysate in the dialysate chamber exchange substances through diffusion/convection in the dialyzer to remove The metabolic waste in the patient's blood and the excess water in the body are maintained, and the electrolyte and acid-base balance are maintained, and then the purified blood is returned to the body from the venous end to achieve the purpose of blood purification in the body.

血液净化治疗使用的体外循环管路和透析器一般都是一次性耗材,为方便灭菌、运输和储存,管路和透析器通常都是在干燥的条件下进行包装的。因此,在开展治疗前,需要采用生理盐水或血液透析设备在线生成的透析液对体外循环管路和透析器进行预冲,以达到排除管路和透析器内的空气的目的,从而避免空气残留并在治疗中进入人体形成空气栓塞以至危及患者生命安全,同时还可避免微小气泡附着在透析器中空纤维膜上而引起的透析器凝血。The extracorporeal circulation pipelines and dialyzers used in blood purification treatment are generally disposable consumables. In order to facilitate sterilization, transportation and storage, the pipelines and dialyzers are usually packaged in dry conditions. Therefore, before starting treatment, it is necessary to pre-flush the extracorporeal circulation pipeline and dialyzer with normal saline or dialysate generated online by hemodialysis equipment, so as to achieve the purpose of removing air in the pipeline and dialyzer, so as to avoid air residue. In the treatment, it enters the human body to form an air embolism and endangers the life of the patient. At the same time, it can also avoid the coagulation of the dialyzer caused by the tiny air bubbles adhering to the hollow fiber membrane of the dialyzer.

目前血液净化治疗前的预冲方法为:将体外循环管路的动脉管路的泵管安装到血泵中,将动脉管路的一端连接到生理盐水或透析液口,另一端连接到透析器动脉端,将体外循环管路的静脉管路两端分别连接到透析器的静脉端和废液袋,启动血泵,流量设置为80~100ml/min,使生理盐水经血泵流经透析器、静脉端。此时的血泵速度不宜过快,否则会影响管路和透析器的排气效果,为便于排净透析管路和透析器血液室(膜内)气体,此时透析器与动脉管路连接的部分应朝下,在透析器血液室预冲过程中,需要拍打透析器,手动或通过液面调节泵调节动静脉壶的液面高度,使透析器中空纤维膜内和管路中气体充分排净。因透析器膜内外液体需形成对流,此时需翻转透析器,让透析器与动脉管路连接的部分应朝上,以便排净透析器透析液室(膜外)的气体。透析器透析液室预冲完成后,需将体外循环管路的动脉端与静脉端短接进行密闭式循环预冲,此时需在透析机参数中设置一定超滤量,使液体能从透析器中空纤维膜内超滤到膜外进行跨膜冲洗,同时进一步排净透析器和管路中的气体,至此,冲洗过程完成。在上述预冲过程中,需根据不同预冲阶段手动调节血泵流量、翻转透析器、调节动脉壶和静脉壶液面、设置各种参数,整体操作比较繁琐,整个预冲过程需持续十分钟以上,并且操作者在此过程中不能离开设备,因此在透析准备的预冲过程是透析室最繁忙的时候,医护人员此次的操作劳动强度非常大,且经常容易出现误操作的情况,如导致预冲不充分或透析器破膜等,影响治疗效果,造成不必要的损失。The current pre-flushing method before blood purification treatment is: install the pump tube of the arterial pipeline of the extracorporeal circulation pipeline into the blood pump, connect one end of the arterial pipeline to the normal saline or dialysate port, and connect the other end to the dialyzer At the arterial end, connect the two ends of the venous line of the extracorporeal circulation line to the venous end of the dialyzer and the waste bag respectively, start the blood pump, and set the flow rate to 80-100ml/min, so that the normal saline flows through the dialyzer through the blood pump. venous end. At this time, the blood pump speed should not be too fast, otherwise the exhaust effect of the pipeline and the dialyzer will be affected. During the pre-flushing process of the blood chamber of the dialyzer, it is necessary to tap the dialyzer and adjust the liquid level of the arteriovenous jug manually or through the liquid level adjustment pump, so that the gas in the hollow fiber membrane of the dialyzer and in the pipeline is sufficient. Drain. Because the liquid inside and outside the dialyzer membrane needs to form convection, the dialyzer needs to be turned over at this time, so that the part connecting the dialyzer and the arterial pipeline should face upwards, so as to remove the gas in the dialysate chamber (outside the membrane) of the dialyzer. After the dialyzer dialysate chamber pre-flushing is completed, the arterial end and the venous end of the extracorporeal circulation pipeline need to be short-circuited to perform a closed cycle pre-flushing. The inside of the hollow fiber membrane of the dialyzer is ultrafiltered to the outside of the membrane for transmembrane flushing, and at the same time, the gas in the dialyzer and the pipeline is further discharged. At this point, the flushing process is completed. In the above-mentioned priming process, it is necessary to manually adjust the blood pump flow, turn over the dialyzer, adjust the fluid levels of the arterial jug and venous jug, and set various parameters according to different priming stages. The above, and the operator cannot leave the equipment during this process, so when the pre-flushing process of dialysis preparation is the busiest time in the dialysis room, the operation of the medical staff is very labor-intensive, and it is often prone to misoperation, such as Lead to insufficient pre-flushing or rupture of the dialyzer membrane, etc., affecting the treatment effect and causing unnecessary losses.

发明内容SUMMARY OF THE INVENTION

为解决上述技术问题,本发明的目的在于提供一种血液净化设备体外循环系统及其自动预冲方法,可有效地解决现有技术中存在的问题,以最大限度的简化透析治疗准备的操作步骤,减少误操作的几率,并降低医护人员操作劳动强。In order to solve the above-mentioned technical problems, the purpose of the present invention is to provide an extracorporeal circulation system of blood purification equipment and an automatic pre-priming method thereof, which can effectively solve the problems existing in the prior art and simplify the operation steps of dialysis treatment preparation to the greatest extent. , reduce the probability of misoperation, and reduce the labor force of medical staff.

为达到上述技术效果,本发明采用了以下技术方案:In order to achieve above-mentioned technical effect, the present invention adopts following technical scheme:

第一方面,本发明提供的一种血液净化设备体外循环系统,包括:In the first aspect, the present invention provides an extracorporeal circulation system for blood purification equipment, including:

透析器,所述透析器通过半透膜分隔为血液室和透析液室,并同时设有与所述血液室连通的血室上端接口和血室下端接口、与所述透析液室连通的透析液上端接口和透析液下端接口,其中,所述血室上端接口高于所述血室下端接口,所述透析液上端接口高于透析液下端接口;A dialyzer, the dialyzer is divided into a blood chamber and a dialysate chamber by a semipermeable membrane, and is provided with an upper end interface of the blood chamber and a lower end interface of the blood chamber that communicate with the blood chamber, and a dialyzer that communicates with the dialysate chamber. a liquid upper end interface and a dialysate lower end interface, wherein the blood chamber upper end interface is higher than the blood chamber lower end interface, and the dialysate upper end interface is higher than the dialysate lower end interface;

以及体外循环管路,所述体外循环管路包括静脉管路和动脉管路,所述动脉管路的一端连接至所述血室上端接口,所述静脉管路的一端连接至所述血室下端接口。and an extracorporeal circulation pipeline, the extracorporeal circulation pipeline includes a venous pipeline and an arterial pipeline, one end of the arterial pipeline is connected to the upper end interface of the blood chamber, and one end of the venous pipeline is connected to the blood chamber lower interface.

进一步地,所述动脉管路上设有蠕动泵。Further, a peristaltic pump is provided on the arterial pipeline.

进一步地,所述静脉管路上设有空气监测器。Further, an air monitor is provided on the venous line.

进一步地,所述动脉管路上串接有动脉壶,所述静脉管路上串接有静脉壶,且所述动脉壶和静脉壶上分别设有动脉压监测组件和静脉压监测组件。Further, an arterial jug is connected in series on the arterial pipeline, and a venous jug is connected in series on the venous pipeline, and an arterial pressure monitoring component and a venous pressure monitoring component are respectively provided on the arterial jug and the venous jug.

进一步地,所述动脉壶和静脉壶的顶端均设有开口且所述开口处连接有压力监测管,所述压力监测管的末端设有压力监测器,所述压力监测器用于监测所述动脉壶或静脉壶内的压力,同时,所述压力监测器的上游还设有阻水部件。Further, the tops of the arterial pot and the venous pot are provided with openings, and the openings are connected with a pressure monitoring tube, and the end of the pressure monitoring tube is provided with a pressure monitor, and the pressure monitor is used to monitor the arterial. At the same time, the upstream of the pressure monitor is also provided with a water blocking part.

进一步地,所述阻水部件包括外壳体和形成于所述外壳体内部的气体通道,所述外壳体的一端可连接至所述动脉壶或静脉壶,所述外壳体的另一端可连接至所述压力监测管,所述气体通道用于连通所述压力监测管和静脉壶或动脉壶,所述阻水部件在所述气体通道内还设有阻水膜,所述阻水膜可供气体通过。Further, the water blocking member includes an outer casing and a gas channel formed inside the outer casing, one end of the outer casing can be connected to the arterial pot or the venous pot, and the other end of the outer casing can be connected to the The pressure monitoring tube and the gas channel are used to connect the pressure monitoring tube and the venous or arterial jug, and the water blocking component is also provided with a water blocking film in the gas channel, and the water blocking film can be used for gas passes through.

进一步地,所述静脉管路包括位于所述静脉管路上游的第一静脉段和位于所述静脉管路下游并用于连通所述静脉壶与透析器的第二静脉段,所述第一静脉段的一端连接至所述静脉壶的底端,所述第二静脉段的一端由静脉壶的顶端贯穿所述静脉壶并部分延伸至所述静脉壶的内部;Further, the venous line comprises a first venous segment upstream of the venous line and a second venous segment downstream of the venous line and used to communicate the venous jug and the dialyzer, the first venous segment. One end of the segment is connected to the bottom end of the venous kettle, and one end of the second venous segment penetrates the venous kettle from the top of the venous kettle and partially extends to the interior of the venous kettle;

更进一步地,所述第二静脉段位于所述静脉壶内的一端处于静脉壶1/2-4/5高度之间。Further, one end of the second venous segment located in the venous pot is between 1/2-4/5 of the height of the venous pot.

进一步地,所述动脉管路包括位于所述动脉管路上游并用于连通所述透析器和动脉壶的第一动脉段和位于所述动脉管路下游的第二动脉段,所述第一动脉段的一端连接至所述静脉壶的底端,所述第二动脉段的一端由静脉壶的顶端贯穿所述静脉壶并部分延伸至所述动脉壶的内部;Further, the arterial line includes a first arterial segment upstream of the arterial line and used to communicate the dialyzer and the arterial jug, and a second arterial segment downstream of the arterial line, the first artery One end of the segment is connected to the bottom end of the venous jug, and one end of the second arterial segment penetrates the venous jug from the top of the venous jug and partially extends to the interior of the arterial jug;

更进一步地,所述第二动脉段位于所述动脉壶内的一端处于静脉壶1/2-4/5高度之间。Further, one end of the second arterial segment located in the arterial pot is between 1/2-4/5 of the height of the venous pot.

进一步地,还包括血液室供液单元和透析液供液单元,所述血液室供液单元设于所述静脉管路的末端并为所述体外循环系统提供第一预冲液,所述透析液供液单元的输出端连接至所述透析液下端接口并为所述体外循环系统提供第二预冲液。Further, it also includes a blood chamber liquid supply unit and a dialysate liquid supply unit, the blood chamber liquid supply unit is arranged at the end of the venous line and provides the first priming fluid for the extracorporeal circulation system, and the dialysate The output end of the liquid supply unit is connected to the lower end port of the dialysate and provides the second priming fluid for the extracorporeal circulation system.

进一步地,还包括废液回收单元,所述废液回收单元与所述体外循环管路和透析器连通并用于收集流经所述体外循环系统的第一预冲液和第二预冲液。Further, a waste liquid recovery unit is also included, the waste liquid recovery unit is communicated with the extracorporeal circulation pipeline and the dialyzer, and is used for collecting the first priming liquid and the second priming liquid flowing through the extracorporeal circulation system.

进一步地,所述废液回收单元包括第一废液收集器和第二废液收集器,所述第一废液收集器设于所述动脉管路的末端并与所述动脉管路连通,所述第二废液收集器与所述透析液上端接口连通。Further, the waste liquid recovery unit includes a first waste liquid collector and a second waste liquid collector, and the first waste liquid collector is provided at the end of the arterial pipeline and communicated with the arterial pipeline, The second waste liquid collector communicates with the upper end port of the dialysate.

第二方面,本发明还提供一种血液净化设备体外循环系统的自动预冲方法,其特征在于,包括以下步骤:In a second aspect, the present invention also provides an automatic priming method for an extracorporeal circulation system of a blood purification device, characterized in that it includes the following steps:

S1:构建第一预冲通路和第二预冲通路,并将所述血液室供液单元和透析液供液单元分别连接至所述第一预冲通路和第二预冲通路的首端,将废液回收单元连接至所述第一预冲通路和第二预冲通路的末端;S1: constructing a first priming passage and a second priming passage, and connecting the blood chamber liquid supply unit and the dialysate liquid supply unit to the head ends of the first priming passage and the second priming passage, respectively, connecting the waste liquid recovery unit to the ends of the first pre-flushing passage and the second pre-flushing passage;

S2:预冲所述第一预冲通路:S2: Pre-flushing the first pre-flushing passage:

控制所述血液室供液单元为所述第一预冲通路提供第一预冲液,并使得所述第一预冲液沿所述第一预冲通路流动并最终富集至所述废液回收单元;Controlling the blood chamber liquid supply unit to provide a first priming liquid for the first priming passage, and making the first priming liquid flow along the first priming passage and finally enriched to the waste liquid recycling unit;

S3:预冲所述第二预冲通路:S3: Pre-flushing the second pre-flushing passage:

控制所述透析液供液单元为所述第二预冲通路提供第二预冲液,并使得该第二预冲液沿所述第二预冲通路流动并最终富集至废液回收单元;Controlling the dialysate liquid supply unit to provide a second priming liquid for the second priming passage, and making the second priming liquid flow along the second priming passage and finally be enriched to the waste liquid recovery unit;

其中,S2与S3步骤的顺序可交换或同时进行。Wherein, the sequence of steps S2 and S3 can be exchanged or performed simultaneously.

进一步地,所述第一预冲液为无菌生理盐水或透析液中的任意一种,所述透析液为经至少一次无菌过滤的透析液。Further, the first pre-flush is any one of sterile physiological saline or dialysate, and the dialysate is a dialysate that has been sterile filtered at least once.

进一步地,所述第二预冲液为生理盐水、无菌生理盐水或透析液中的任意一种;Further, the second preflush is any one of normal saline, sterile normal saline or dialysate;

进一步地,所述第一预冲通路和第二预冲通路的构建方法具体为:Further, the construction methods of the first pre-flushing passage and the second pre-flushing passage are as follows:

将静脉壶串接至所述静脉管路中并将静脉管路的一端连接至所述血室下端接口,将静脉壶串接至所述动脉管路中并将所述动脉管路的一端连接至所述血室上端接口,此时,所述静脉壶、血室下端接口、血液室、血室上端接口以及动脉壶形成第一预冲通路,所述透析液下端接口、透析液室以及透析液上端接口形成第二预冲通路。Connect the venous pot in series to the venous line and connect one end of the venous line to the lower end port of the blood chamber, connect the venous pot in series to the arterial line and connect one end of the arterial line To the upper end interface of the blood chamber, at this time, the venous jug, the lower end interface of the blood chamber, the blood chamber, the upper end interface of the blood chamber and the arterial jug form a first pre-flushing path, and the lower end interface of the dialysate, the dialysate chamber and the dialysis solution The liquid upper end interface forms a second pre-flushing passage.

进一步地,所述S2具体为:控制所述血液室供液单元为所述第一预冲通路提供第一预冲液,并使得所述第一预冲液以第一流速进入第一预冲通路直至完全充满第一预冲通路,然后使得所述第一预冲液以第二流速在所述第一预冲通路中流动,并最终富集至所述废液回收单元,其中,所述第二流速大于第一流速。Further, the step S2 is specifically: controlling the blood chamber liquid supply unit to provide a first priming liquid for the first priming passage, and making the first priming liquid enter the first priming liquid at a first flow rate until the first pre-flushing channel is completely filled, and then the first pre-flushing liquid flows in the first pre-flushing channel at a second flow rate, and is finally enriched to the waste liquid recovery unit, wherein the The second flow rate is greater than the first flow rate.

进一步地,所述第一流速为80~100ml/min,第二流速为200~300ml/min。Further, the first flow rate is 80-100ml/min, and the second flow rate is 200-300ml/min.

与现有技术相比,本发明的有益效果为:Compared with the prior art, the beneficial effects of the present invention are:

本发明提供的一种血液净化设备体外循环系统,该血液净化设备体外循环系统包括透析器以及体外循环管路,该透析器通过半透膜分隔为血液室和透析液室,且该透析器上同时设有与该血液室连通的血室上端接口和血室下端接口、与该透析液室连通的透析液上端接口和透析液下端接口;该体外循环管路包括静脉管路和动脉管路,其中,该动脉管路的一端连接至该血室上端接口,该静脉管路的一端连接至该血室下端接口。同时,本发明还提供一种血液净化设备体外循环系的自动预冲方法,采用该方法对上述血液净化设备体外循环系统进行预冲时,通过使预冲液由静脉管路进入透析器的血液室中,并最终流入动脉管路中,从而达到对血液净化设备体外循环系统进行有效和自动冲洗的目的,其预冲效果较好,且冲洗过程可自动控制,能够最大限度的简化透析治疗准备的操作步骤,减少误操作的几率,降低医护人员操作劳动强度,减少医院透析室的人力需求。The present invention provides an extracorporeal circulation system for blood purification equipment. The extracorporeal circulation system for blood purification equipment includes a dialyzer and an extracorporeal circulation pipeline. The dialyzer is divided into a blood chamber and a dialysate chamber by a semipermeable membrane, and the dialyzer is on the dialyzer. At the same time, it is provided with an upper end interface of the blood chamber and a lower end interface of the blood chamber, and a dialysate upper end interface and a dialysate lower end interface communicated with the dialysate chamber; the extracorporeal circulation pipeline includes a venous pipeline and an arterial pipeline, Wherein, one end of the arterial pipeline is connected to the upper end port of the blood chamber, and one end of the venous pipeline is connected to the lower end port of the blood chamber. At the same time, the present invention also provides an automatic priming method for the extracorporeal circulation system of the blood purification equipment. When the method is used to precharge the extracorporeal circulation system of the blood purification equipment, the preflushing liquid enters the blood of the dialyzer through the venous line. In the chamber, and finally into the arterial pipeline, so as to achieve the purpose of effective and automatic flushing of the extracorporeal circulation system of the blood purification equipment. It can reduce the probability of misoperation, reduce the labor intensity of medical staff, and reduce the manpower demand of the hospital dialysis room.

附图说明Description of drawings

图1为本发明的实施例1的整体结构示意图;1 is a schematic diagram of the overall structure of Embodiment 1 of the present invention;

图2为本发明的实施例2和实施例3的整体结构示意图;2 is a schematic diagram of the overall structure of Embodiment 2 and Embodiment 3 of the present invention;

附图标记为:10,透析器,11,血液室,11a,血室上端接口,11b,血室下端接口,12,透析液室,12a,透析液上端接口,12b,透析液下端接口,21,动脉壶,21a,第一动脉段,21b,第二动脉段,22,静脉壶,22a,第一静脉段,22b,第二静脉段,23,蠕动泵,24,空气监测器,31,压力监测管,32,压力监测器,33,阻水膜,41,血液室供液单元,42,透析液供液单元,51,第一废液收集器,52,第二废液收集器。Reference numerals: 10, dialyzer, 11, blood chamber, 11a, upper port of blood chamber, 11b, lower port of blood chamber, 12, dialysate chamber, 12a, upper port of dialysate, 12b, lower port of dialysate, 21 , arterial jug, 21a, first arterial segment, 21b, second arterial segment, 22, venous jug, 22a, first venous segment, 22b, second venous segment, 23, peristaltic pump, 24, air monitor, 31, Pressure monitoring tube, 32, pressure monitor, 33, water blocking membrane, 41, blood chamber liquid supply unit, 42, dialysate liquid supply unit, 51, first waste liquid collector, 52, second waste liquid collector.

具体实施方式Detailed ways

下面将结合附图对本发明技术方案的实施例进行详细的描述。以下实施例仅用于更加清楚地说明本发明的技术方案,因此只作为示例,而不能以此来限制本发明的保护范围。Embodiments of the technical solutions of the present invention will be described in detail below with reference to the accompanying drawings. The following examples are only used to more clearly illustrate the technical solutions of the present invention, and are therefore only used as examples, and cannot be used to limit the protection scope of the present invention.

如无特殊说明,在本发明中,若有术语“长度”、“宽度”、“上”、“下”、“前”、“后”、“左”、“右”、“竖直”、“水平”、“顶”、“底”“内”、“外”、“顺时针”、“逆时针”、“轴向”、“径向”、“周向”等指示的方位或位置关系是基于附图所示的方位或位置关系,仅是为了便于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此本发明中描述方位或位置关系的用语仅用于示例性说明,不能理解为对本专利的限制,对于本领域的普通技术人员而言,可以结合附图,并根据具体情况理解上述术语的具体含义。Unless otherwise specified, in the present invention, if the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. Based on the orientation or positional relationship shown in the drawings, it is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, so this The terms describing the orientation or positional relationship in the invention are only used for exemplary illustration, and should not be construed as a limitation on this patent. For those of ordinary skill in the art, the specific meanings of the above terms can be understood according to specific situations with reference to the accompanying drawings.

需要特殊说明的是,在本发明中,术语“上游”和“下游”是指以流体流动方向为基准,“上游”指流体从其流动的方向,“下游”指流体流到其的方向,此处“流体流动方向”指由静脉管路流向动脉管路的方向。It should be noted that, in the present invention, the terms "upstream" and "downstream" refer to the direction of fluid flow as a reference, "upstream" refers to the direction from which the fluid flows, and "downstream" refers to the direction from which the fluid flows, Here, "fluid flow direction" refers to the direction of flow from the venous line to the arterial line.

实施例1Example 1

请参阅图1,以下为本发明的第一实施例,本实施例提供一种血液净化设备体外循环系统,可用于血液透析治疗,具体地:Referring to FIG. 1, the following is the first embodiment of the present invention. This embodiment provides an extracorporeal circulation system for blood purification equipment, which can be used for hemodialysis treatment, specifically:

本实施例所提供的一种血液净化设备体外循环系统,包括透析器10和体外循环管路,其中,该透析器10通过半透膜分隔为血液室11和透析液室12,该透析器10上还设有与所述血液室11连通的血室上端接口11a和血室下端接口11b、与所述透析液室12连通的透析液上端接口12a和透析液下端接口12b,并且,该血室上端接口11a高于所述血室下端接口11b,所述透析液上端接口12a高于透析液下端接口12b。而该体外循环管路则包括静脉管路和动脉管路,该静脉管路的组成包括第一静脉段22a、静脉壶22以及第二静脉段22b,该动脉管路的组成包括第一动脉段21a、动脉壶21以及第二动脉段21b,其中,该第一静脉段22a位于第二静脉段22b的上游,该第一动脉段21a位于第二动脉段21b的上游,且该体外循环管路与透析器10的连接方式如下:An extracorporeal circulation system for blood purification equipment provided in this embodiment includes a dialyzer 10 and an extracorporeal circulation pipeline, wherein the dialyzer 10 is divided into a blood chamber 11 and a dialysate chamber 12 by a semipermeable membrane. The dialyzer 10 There is also a blood chamber upper port 11a and a blood chamber lower port 11b communicating with the blood chamber 11, a dialysate upper port 12a and a dialysate lower port 12b communicating with the dialysate chamber 12, and the blood chamber The upper port 11a is higher than the lower port 11b of the blood chamber, and the dialysate upper port 12a is higher than the dialysate lower port 12b. The extracorporeal circulation pipeline includes a venous pipeline and an arterial pipeline, the venous pipeline includes a first venous segment 22a, a venous jug 22 and a second venous segment 22b, and the arterial pipeline consists of a first arterial segment 21a, the arterial pot 21 and the second arterial segment 21b, wherein the first venous segment 22a is located upstream of the second venous segment 22b, the first arterial segment 21a is located upstream of the second arterial segment 21b, and the extracorporeal circulation pipeline The connection to the dialyzer 10 is as follows:

第一静脉段22a的末端连接至所述静脉壶22的底端,所述第二静脉段22b用于连通所述所述静脉壶22与透析器10,具体而言,该第二静脉段22b的首端由静脉壶22的顶端贯穿所述静脉壶22并延伸至所述静脉壶22内,且该第二静脉段22b的首端高度处于所述静脉壶22高度的2/3左右处,该第二静脉段22b的末端连接至所述透析器10的血室下端接口11b。所述第一动脉段21a的首端连接至所述透析器10的血室上端接口11a,该第一动脉段21a的末端连接至所述动脉壶21的底端,该第二动脉段21b的首端由静脉壶22的顶端贯穿所述静脉壶22并延伸至所述动脉壶21的内部且处于所述动脉壶21高度的2/3左右处。The end of the first venous segment 22a is connected to the bottom end of the venous kettle 22, and the second venous segment 22b is used to communicate the venous kettle 22 and the dialyzer 10. Specifically, the second venous segment 22b The head end of the venous pot 22 penetrates through the venous pot 22 and extends into the venous pot 22, and the height of the head end of the second venous segment 22b is about 2/3 of the height of the venous pot 22, The end of the second vein segment 22b is connected to the lower end port 11b of the blood chamber of the dialyzer 10 . The head end of the first arterial segment 21a is connected to the upper end port 11a of the blood chamber of the dialyzer 10, the end of the first arterial segment 21a is connected to the bottom end of the arterial pot 21, and the second arterial segment 21b is The head end penetrates the venous jug 22 from the top of the venous jug 22 and extends to the inside of the arterial jug 21 and is located at about 2/3 of the height of the arterial jug 21 .

本实施例提供的一种血液净化设备体外循环系统在治疗模式下,血液净化设备体外循环系统中液体流向为:通过将患者血液由第二动脉段21b的末端引入该动脉管路中并使其流经透析器10的血液室11,在该透析器10内通过弥散/对流进行物质交换,以清除患者血液中的代谢废物和体内过多的水分,并维持电解质和酸碱平衡,以对血液起到净化效果,在净化完成后通过第二静脉段22b将该净化后的血液引入静脉管路中并最终通过第一静脉段22a输回患者体内。In the treatment mode of the extracorporeal circulation system of the blood purification device provided by this embodiment, the liquid flow in the extracorporeal circulation system of the blood purification device is as follows: by introducing the patient's blood from the end of the second arterial segment 21b into the arterial pipeline and making it It flows through the blood chamber 11 of the dialyzer 10, where material exchange is carried out by diffusion/convection in the dialyzer 10 to remove metabolic wastes and excess water in the patient's blood, and to maintain electrolyte and acid-base balance, so that blood To achieve a purification effect, after the purification is completed, the purified blood is introduced into the venous line through the second venous segment 22b and finally returned to the patient through the first venous segment 22a.

在本实施例中,所述动脉壶21和静脉壶22上还分别设有动脉压监测组件和静脉压监测组件,所述动脉压监测组件和静脉压监测组件分别用于对动脉管路和静脉管路中的压力进行监测,以在治疗模式和预冲模式下用于确保该血液净化设备体外循环系统中的流体正常流动,具体而言,为对该动脉管路和静脉管路中的压力进行监测,所述动脉壶21和静脉壶22的顶端均设有开口且所述开口处连接有压力监测管31,所述压力监测管31的末端设有压力监测器32,所述压力监测器32用于监测所述动脉壶21或静脉壶22内的压力,同时,所述压力监测器32的上游还设有阻水部件。具体而言,该阻水部件包括外壳体和形成于所述外壳体内部的气体通道,所述外壳体的一端可连接至所述动脉壶21或静脉壶22,所述外壳体的另一端可连接至所述压力监测管31,所述气体通道用于连通所述压力监测管31和静脉壶21或动脉壶22,以便于对静脉壶21或动脉壶22内压力进行检测,而该阻水部件在所述气体通道内还设有阻水膜33,所述阻水膜33由非亲水材料制成且可供气体通过,以避免该动脉壶21或静脉壶22中的液体透过该阻水膜33进而进入该压力监测管31内而导致的交叉感染。In this embodiment, the arterial pot 21 and the venous pot 22 are further provided with an arterial pressure monitoring component and a venous pressure monitoring component, respectively, and the arterial pressure monitoring component and the venous pressure monitoring component are respectively used for monitoring the arterial pipeline and the venous pressure. Monitoring of the pressure in the circuit for ensuring proper flow of fluid in the extracorporeal circulation system of the blood purification device in therapy mode and priming mode, in particular, the pressure in the arterial and venous circuits For monitoring, the tops of the arterial pot 21 and the venous pot 22 are both provided with openings and the openings are connected with a pressure monitoring tube 31, the end of the pressure monitoring tube 31 is provided with a pressure monitor 32, and the pressure monitor 32 is used to monitor the pressure in the arterial jug 21 or the venous jug 22, and at the same time, the upstream of the pressure monitor 32 is also provided with a water blocking member. Specifically, the water blocking member includes an outer casing and a gas channel formed inside the outer casing, one end of the outer casing can be connected to the arterial pot 21 or the venous pot 22, and the other end of the outer casing can be connected to the arterial pot 21 or the venous pot 22 Connected to the pressure monitoring tube 31, the gas channel is used to communicate the pressure monitoring tube 31 and the venous kettle 21 or the arterial kettle 22, so as to detect the pressure in the venous kettle 21 or the arterial kettle 22, and the water blocking The component is also provided with a water blocking film 33 in the gas channel, and the water blocking film 33 is made of non-hydrophilic material and can allow gas to pass through, so as to prevent the liquid in the arterial pot 21 or the venous pot 22 from passing through the The water blocking membrane 33 further enters the pressure monitoring tube 31 and causes cross infection.

在本实施例中,所述动脉管路上设有蠕动泵23,在治疗模式和预冲模式下,该蠕动泵23均用于推动所述体外循环系统中的液体在该体外循环系统内流动,同时,该静脉管路的第一静脉段22a上还设有空气监测器24,在治疗模式下,该空气监测器24的设置可确保经由该第一静脉段22a输回患者体内的血液中不含有空气。In this embodiment, the arterial pipeline is provided with a peristaltic pump 23. In both the treatment mode and the pre-charge mode, the peristaltic pump 23 is used to push the liquid in the extracorporeal circulation system to flow in the extracorporeal circulation system, At the same time, an air monitor 24 is also provided on the first venous segment 22a of the venous line. In the treatment mode, the setting of the air monitor 24 can ensure that the blood returned to the patient through the first venous segment 22a will not be contained in the blood. Contains air.

在本实施例中,所述血液净化设备体外循环系统还包括控制器,所述蠕动泵23和空气监测器24均电连接或信号连接至所述控制器,以便于在治疗模式或预冲模式下对该血液净化设备体外循环系统中的液体流速进行控制,同时,该空气监测器24则实时地对该第一静脉段22a中是否含有空气进行监测,并将监测结果实时反馈至该控制器,以便于操作人员在治疗过程或预冲过程中及时地对该血液净化设备体外循环系统的工作状态进行调整。In this embodiment, the extracorporeal circulation system of the blood purification apparatus further includes a controller, and the peristaltic pump 23 and the air monitor 24 are both electrically connected or signally connected to the controller, so as to facilitate the treatment mode or the pre-charge mode. The liquid flow rate in the extracorporeal circulation system of the blood purification equipment is controlled under the following conditions, and at the same time, the air monitor 24 monitors whether the first venous segment 22a contains air in real time, and feeds back the monitoring results to the controller in real time. , so that the operator can adjust the working state of the extracorporeal circulation system of the blood purification equipment in a timely manner during the treatment process or the pre-flushing process.

实施例2Example 2

请参阅图2,以下为本发明的第二实施例,本实施例提供一种可进行自动预冲的血液净化设备体外循环系统,具体地,该可进行自动预冲的血液净化设备体外循环系统在实施例所提供的一种血液净化设备体外循环系统的基础上还进一步包括:血液室11供液单元、透析液供液单元42以及废液回收单元。Referring to FIG. 2 , the following is the second embodiment of the present invention. This embodiment provides an extracorporeal circulation system for blood purification equipment that can perform automatic preflushing. Specifically, the extracorporeal circulation system for blood purification equipment that can perform automatic priming is provided. On the basis of the extracorporeal circulation system of the blood purification equipment provided in the embodiment, it further includes: a liquid supply unit of the blood chamber 11 , a dialysate liquid supply unit 42 and a waste liquid recovery unit.

在本实施例中,该血液室11供液单元连接至所述第一静脉段22a的上游并为所述体外循环系统提供第一预冲液,所述透析液供液单元42设于所述透析液下端接口12b的上游并为所述体外循环系统提供第二预冲液。而该废液回收单元则包括第一废液收集器51和第二废液收集器52,其中,该第一废液收集器51设于所述第二动脉管路的末端并与所述动脉管路连通,所述第二废液收集器52设于所述透析液上端接口12a的下游并与所述透析液上端接口12a连通。此时,该可进行自动预冲的血液净化设备体外循环系统中形成第一预冲通路和第二预冲通路,所述第一预冲通路依次经过相互连通的第一静脉段22a、静脉壶22、第二静脉段22b、血室下端接口11b、血液室11、血室上端接口11a、第一动脉段21a、动脉壶21和第二动脉段21b,且该第一预冲通路的首端还连接有血液室11供液单元、末端连接有第一废液收集器51;而该第二预冲通路依次经过相互连通的透析液下端接口12b、透析液室12以及透析液上端接口12a,并且该第二预冲通路的首端还连接有透析液供液单元42、末端连接有第二废液收集器52。In this embodiment, the blood chamber 11 liquid supply unit is connected to the upstream of the first venous segment 22a and provides the first priming fluid for the extracorporeal circulation system, and the dialysate liquid supply unit 42 is provided in the The dialysate lower end port 12b is upstream and provides the second priming fluid for the extracorporeal circulation system. The waste liquid recovery unit includes a first waste liquid collector 51 and a second waste liquid collector 52, wherein the first waste liquid collector 51 is provided at the end of the second arterial pipeline and is connected with the arterial The pipeline is connected, and the second waste liquid collector 52 is arranged downstream of the upper end port 12a of the dialysate and communicated with the upper port 12a of the dialysate. At this time, the extracorporeal circulation system of the blood purification device capable of automatic priming is formed with a first priming passage and a second priming passage, and the first priming passage passes through the first venous segment 22a, the venous pot which are connected to each other in turn. 22. The second venous segment 22b, the lower end port 11b of the blood chamber, the blood chamber 11, the upper end port 11a of the blood chamber, the first arterial segment 21a, the arterial pot 21 and the second arterial segment 21b, and the head end of the first pre-flushing passage The blood chamber 11 liquid supply unit is also connected, and the first waste liquid collector 51 is connected at the end; and the second pre-flushing passage passes through the dialysate lower end interface 12b, the dialysate chamber 12 and the dialysate upper end interface 12a which are communicated with each other in turn, In addition, the first end of the second pre-flushing channel is also connected with the dialysate liquid supply unit 42, and the end is connected with the second waste liquid collector 52.

在预冲模式下,由该血液室11供液单元通过向所述第一预冲通路中输入第一预冲液,该第一预冲液沿该第一预冲通路进行流动以达到对第一预冲通路进行预冲的目的,而该第二预冲通路的预冲则通过该透析液供液单元42向所述第二预冲通路中输入第二预冲液并使得该第二预冲液沿第二预冲通路流动实现,最终,流经该第一预冲通路的第一预冲液通过第一废液收集器51进行收集,而流经该第二预冲通路的第二预冲液通过第二废液收集器52进行收集。可选地,该第二废液收集器52和第一废液收集器51之间还可以通过废液输送管道进行连通,以将该血液净化设备体外循环系统在预冲模式下产生的全部废液进行富集。In the priming mode, the first priming liquid is fed into the first priming passage by the liquid supply unit of the blood chamber 11, and the first priming liquid flows along the first priming passage to achieve the first priming liquid. A pre-flushing channel is used for the purpose of pre-flushing, and the pre-flushing of the second pre-flushing channel is to input the second pre-flushing liquid into the second pre-flushing channel through the dialysate liquid supply unit 42 and make the second pre-flushing channel. The flushing liquid flows along the second pre-flushing passage, and finally, the first pre-flushing liquid flowing through the first pre-flushing passage is collected by the first waste liquid collector 51, while the second pre-flushing liquid flowing through the second pre-flushing passage is collected by the first waste liquid collector 51 The priming liquid is collected by the second waste liquid collector 52 . Optionally, the second waste liquid collector 52 and the first waste liquid collector 51 can also be communicated through a waste liquid conveying pipeline, so that all the waste liquid generated by the extracorporeal circulation system of the blood purification equipment in the pre-flushing mode can be connected. liquid for enrichment.

实施例3Example 3

请参阅图2,以下为本发明的第三实施例,本实施例提供一种血液净化设备体外循环系统及其自动预冲方法,该方法具体包括以下步骤:Please refer to FIG. 2 , the following is the third embodiment of the present invention. The present embodiment provides an extracorporeal circulation system for blood purification equipment and an automatic priming method thereof. The method specifically includes the following steps:

在本实施例中,所述血液净化设备体外循环系统的控制器的输出端还连接有第一提示器和第二提示器,所述第一提示器和第二提示器分别对应第一异常状态和第二异常状态。In this embodiment, the output end of the controller of the extracorporeal circulation system of the blood purification device is further connected with a first prompter and a second prompter, and the first prompter and the second prompter respectively correspond to the first abnormal state and the second abnormal state.

在本实施例中,所述血液净化设备体外循环系统的自动预冲方法具体包括以下步骤:In this embodiment, the automatic priming method of the extracorporeal circulation system of the blood purification equipment specifically includes the following steps:

S1:以实施例2提供的可进行自动预冲的血液净化设备体外循环系统为基础,将第一静脉段22a、静脉壶22、第二静脉段22b、血室下端接口11b、血液室11、血室上端接口11a、第一动脉段21a、动脉壶21和第二动脉段21b进行顺次连接以形成第一预冲通路,并将血液室11供液单元和第一废液收集器51分别连接至该第一预冲通路的首端和末端。以实施例2提供的可进行自动预冲的血液净化设备体外循环系统为基础,将透析液供液单元42和第二废液收集器52分别连接至所述第二预冲通路的首端和末端。S1: Based on the extracorporeal circulation system of the blood purification equipment that can be automatically pre-filled provided in Example 2, the first venous segment 22a, the venous pot 22, the second venous segment 22b, the lower end interface 11b of the blood chamber, the blood chamber 11, The upper port 11a of the blood chamber, the first arterial segment 21a, the arterial pot 21 and the second arterial segment 21b are connected in sequence to form a first pre-flushing passage, and the blood chamber 11 liquid supply unit and the first waste liquid collector 51 are respectively connected. Connected to the first end and the end of the first priming passage. Based on the extracorporeal circulation system of the blood purification equipment that can perform automatic priming provided in Example 2, the dialysate liquid supply unit 42 and the second waste liquid collector 52 are respectively connected to the head end and the first end of the second priming passage. end.

S2:预冲所述第一预冲通路,具体为:在第一预冲阶段,由控制器控制蠕动泵23工作以使血液室11供液单元为所述第一预冲通路提供第一预冲液,并使得所述第一预冲液以为80~100ml/min的流速进入第一预冲通路直至完全充满第一预冲通路,当该第一预冲通路完全充满后,进入第二预冲阶段,此时,改变该第一预冲液的流速使其以200~300ml/min的流速在第一预冲通路中流动,在第二预冲阶段中,通过提高蠕动泵23的输送速度,可有效地提升对第一预冲通路的冲洗效果,利于将第一预冲通路中附着的微小气泡冲走。S2: Pre-flushing the first pre-flushing channel, specifically: in the first pre-flushing stage, the controller controls the peristaltic pump 23 to work so that the liquid supply unit of the blood chamber 11 provides the first pre-flushing channel for the first pre-flushing channel. and make the first pre-flushing liquid enter the first pre-flushing passage at a flow rate of 80-100 ml/min until the first pre-flushing passage is completely filled. In the flushing stage, at this time, the flow rate of the first priming liquid is changed to flow in the first priming passage at a flow rate of 200-300 ml/min. In the second priming stage, by increasing the delivery speed of the peristaltic pump 23 , which can effectively improve the flushing effect of the first pre-flushing passage, which is beneficial to flush away the tiny air bubbles attached to the first pre-flushing passage.

在该第一预冲阶段和第二预冲阶段中,流经该第一预冲通路的第一预冲液最终通过该第一废液收集器51进行收集。In the first priming stage and the second priming stage, the first priming liquid flowing through the first priming passage is finally collected by the first waste liquid collector 51 .

在该第一预冲阶段和第二预冲阶段中,该空气监测器24、以及设于动脉壶21和静脉壶22上的压力监测器32可同时对血液净化设备体外循环系统的工作状态进行监测并反馈至该控制器,以确保在该第一预冲阶段和第二预冲阶段中,该第一预冲通路处于正常工作状态。具体而言,在该第一预冲阶段和第二预冲阶段中,通过所述空气监测器24对该第一预冲通路中是否存在空气进行实时监测并反馈至所述控制器,当该空气监测器24的检测结果异常时,由所述控制器控制该第一提示器发出提示信号,以提示操作人员对该血液室11供液单元的供液状态进行确认和调整。在该第一预冲阶段和第二预冲阶段中,通过设于所述动脉壶21和静脉壶22上的压力监测器32分别对该动脉管路和静脉管路的压力进行监测并反馈至该控制器,当该压力监测器32监测结果异常时,由该控制器控制该第二提示器发出提示信号,以提示操作人员对该第一预冲通路的连接状态进行确认和调整。In the first and second priming stages, the air monitor 24 and the pressure monitor 32 provided on the arterial pot 21 and the venous pot 22 can simultaneously monitor the working state of the extracorporeal circulation system of the blood purification apparatus. Monitoring and feedback to the controller to ensure that the first priming passage is in normal working condition during the first priming stage and the second priming stage. Specifically, in the first priming stage and the second priming stage, whether there is air in the first priming passage is monitored in real time by the air monitor 24 and fed back to the controller. When the detection result of the air monitor 24 is abnormal, the controller controls the first prompter to issue a prompt signal to prompt the operator to confirm and adjust the liquid supply state of the liquid supply unit of the blood chamber 11 . In the first priming stage and the second priming stage, the pressures of the arterial pipeline and the venous pipeline are monitored and fed back to In the controller, when the monitoring result of the pressure monitor 32 is abnormal, the controller controls the second prompter to issue a prompt signal to prompt the operator to confirm and adjust the connection state of the first pre-flushing passage.

S3:预冲所述第二预冲通路:S3: Pre-flushing the second pre-flushing passage:

由所述控制器控制该透析液供液单元42为所述第二预冲通路提供第二预冲液,该第二预冲液经过透析液下端接口12b进入该透析液室12内、然后通过透析液上端接口12a流出并最终通过该第二废液收集器52进行收集。The dialysate supply unit 42 is controlled by the controller to provide a second preflush for the second preflush passage. The second preflush enters the dialysate chamber 12 through the dialysate lower port 12b, and then passes through The dialysate upper port 12a flows out and is finally collected by the second waste liquid collector 52 .

同时,需要注意的是,上述S2与S3步骤的顺序可交换或同时进行。Meanwhile, it should be noted that the order of the above steps S2 and S3 can be interchanged or performed simultaneously.

此外,在本实施例中,由于预冲模式实施于治疗模式之前,因此,该第一预冲液为无菌生理盐水或透析液中的任意一种,所述透析液为经过1-2次无菌过滤的透析液,而由于半透膜的设置,该第二预冲液可选择生理盐水、无菌生理盐水、透析液或经过1-2次无菌过滤的透析液中的任意一种,并且,该第一预冲液和第二预冲液可预先配制为成品或通过在线配制获得,且该透析液供液单元中至少包含一个用于输送流体的泵。In addition, in this embodiment, since the pre-flushing mode is implemented before the treatment mode, the first pre-flushing solution is any one of sterile physiological saline or dialysate, and the dialysate is processed 1-2 times Sterile filtered dialysate, and due to the setting of the semi-permeable membrane, the second preflush can be selected from any one of physiological saline, sterile physiological saline, dialysate or dialysate that has been sterile filtered 1-2 times , and the first pre-flushing solution and the second pre-flushing solution can be pre-prepared as finished products or obtained through online preparation, and the dialysate liquid supply unit includes at least one pump for delivering fluid.

以上实施例仅用以说明本发明的技术方案而非限制,尽管参照较佳实施例对本发明进行了详细说明,本领域的普通技术人员应当理解,可以对本发明的技术方案进行修改或者等同替换,而不脱离本发明技术方案的宗旨和范围,其均应涵盖在本发明的权利要求范围当中。本发明未详细描述的技术、形状、构造部分均为公知技术。The above embodiments are only used to illustrate the technical solutions of the present invention and not to limit them. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be modified or equivalently replaced. Without departing from the spirit and scope of the technical solutions of the present invention, all of them should be included in the scope of the claims of the present invention. The technology, shape, and structural part that are not described in detail in the present invention are all well-known technologies.

Claims (10)

1.一种血液净化设备体外循环系统,其特征在于:1. a blood purification equipment extracorporeal circulation system is characterized in that: 透析器(10),所述透析器(10)通过半透膜分隔为血液室(11)和透析液室(12),并同时设有与所述血液室(11)连通的血室上端接口(11a)和血室下端接口(11b)、与所述透析液室(12)连通的透析液上端接口(12a)和透析液下端接口(12b),其中,所述血室上端接口(11a)高于所述血室下端接口(11b),所述透析液上端接口(12a)高于透析液下端接口(12b);A dialyzer (10), the dialyzer (10) is divided into a blood chamber (11) and a dialysate chamber (12) by a semi-permeable membrane, and is provided with a blood chamber upper end interface communicating with the blood chamber (11) at the same time (11a) and the lower port of the blood chamber (11b), the upper port of the dialysate (12a) and the lower port of the dialysate (12b) communicated with the dialysate chamber (12), wherein the upper port of the blood chamber (11a) higher than the lower port (11b) of the blood chamber, and the upper port (12a) of the dialysate is higher than the lower port (12b) of the dialysate; 以及体外循环管路,所述体外循环管路包括静脉管路和动脉管路,所述动脉管路的一端连接至所述血室上端接口(11a),所述静脉管路的一端连接至所述血室下端接口(11b)。and an extracorporeal circulation pipeline, the extracorporeal circulation pipeline includes a venous pipeline and an arterial pipeline, one end of the arterial pipeline is connected to the upper end interface (11a) of the blood chamber, and one end of the venous pipeline is connected to the Describe the lower end port (11b) of the blood chamber. 2.如权利要求1所述的一种血液净化设备体外循环系统,其特征在于:所述动脉管路上设有蠕动泵(23)。2. The extracorporeal circulation system for blood purification equipment according to claim 1, wherein a peristaltic pump (23) is provided on the arterial pipeline. 3.如权利要求1所述的一种血液净化设备体外循环系统,其特征在于:所述静脉管路上设有空气监测器(24)。3. The extracorporeal circulation system for blood purification equipment according to claim 1, wherein an air monitor (24) is provided on the venous line. 4.如权利要求1所述的一种血液净化设备体外循环系统,其特征在于:所述动脉管路上串接有动脉壶(21),所述静脉管路上串接有静脉壶(22),且所述动脉壶(21)和静脉壶(22)上分别设有动脉压监测组件和静脉压监测组件。4. The extracorporeal circulation system of a blood purification device according to claim 1, wherein the arterial jug (21) is connected in series on the arterial pipeline, and the venous jug (22) is connected in series on the venous pipeline, And the arterial pot (21) and the venous pot (22) are respectively provided with an arterial pressure monitoring component and a venous pressure monitoring component. 5.如权利要求1所述的一种血液净化设备体外循环系统,其特征在于:还包括血液室(11)供液单元和透析液供液单元(42),所述血液室(11)供液单元设于所述静脉管路的末端并为所述体外循环系统提供第一预冲液,所述透析液供液单元(42)的输出端连接至所述透析液下端接口(12b)并为所述体外循环系统提供第二预冲液。5. An extracorporeal circulation system for blood purification equipment according to claim 1, characterized in that: further comprising a blood chamber (11) liquid supply unit and a dialysate liquid supply unit (42), wherein the blood chamber (11) supplies A fluid unit is arranged at the end of the venous line and provides the first priming fluid for the extracorporeal circulation system, and the output end of the dialysate fluid supply unit (42) is connected to the dialysate lower end port (12b) and A second priming fluid is provided for the extracorporeal circulation system. 6.如权利要求5所述的一种血液净化设备体外循环系统,其特征在于:还包括废液回收单元,所述废液回收单元与所述体外循环管路和透析器(10)连通并用于收集流经所述体外循环系统的第一预冲液和第二预冲液。6. a kind of blood purification equipment extracorporeal circulation system as claimed in claim 5 is characterized in that: also comprises waste liquid recovery unit, and described waste liquid recovery unit communicates with described extracorporeal circulation pipeline and dialyzer (10) and uses The first priming fluid and the second priming fluid flowing through the extracorporeal circulation system are collected. 7.如权利要求6所述的一种血液净化设备体外循环系统,其特征在于:所述废液回收单元包括第一废液收集器(51)和第二废液收集器(52),所述第一废液收集器(51)设于所述动脉管路的末端并与所述动脉管路连通,所述第二废液收集器(52)与所述透析液上端接口(12a)连通。7. The extracorporeal circulation system of a blood purification device according to claim 6, wherein the waste liquid recovery unit comprises a first waste liquid collector (51) and a second waste liquid collector (52), The first waste liquid collector (51) is provided at the end of the arterial pipeline and communicated with the arterial pipeline, and the second waste liquid collector (52) is communicated with the dialysate upper end interface (12a) . 8.如权利要求1-7任意一项所述的一种血液净化设备体外循环系统的自动预冲方法,其特征在于,包括以下步骤:8. the automatic priming method of a kind of blood purification equipment extracorporeal circulation system as described in any one of claim 1-7, is characterized in that, comprises the following steps: S1:构建第一预冲通路和第二预冲通路,并将所述血液室(11)供液单元和透析液供液单元(42)分别连接至所述第一预冲通路和第二预冲通路的首端,将废液回收单元连接至所述第一预冲通路和第二预冲通路的末端;S1: Build a first priming channel and a second priming channel, and connect the blood chamber (11) liquid supply unit and the dialysate liquid supply unit (42) to the first and second priming channels, respectively the head end of the flushing passage, connecting the waste liquid recovery unit to the ends of the first pre-flushing passage and the second pre-flushing passage; S2:预冲所述第一预冲通路:S2: Pre-flushing the first pre-flushing passage: 控制所述血液室(11)供液单元为所述第一预冲通路提供第一预冲液,并使得所述第一预冲液沿所述第一预冲通路流动并最终富集至所述废液回收单元;Controlling the liquid supply unit of the blood chamber (11) to provide the first priming liquid for the first priming passage, and making the first priming liquid flow along the first priming passage and finally enriched to the the waste liquid recovery unit; S3:预冲所述第二预冲通路:S3: Pre-flushing the second pre-flushing passage: 控制所述透析液供液单元(42)为所述第二预冲通路提供第二预冲液,并使得该第二预冲液沿所述第二预冲通路流动并最终富集至废液回收单元;Controlling the dialysate liquid supply unit (42) to provide a second priming liquid for the second priming passage, and making the second priming liquid flow along the second priming passage and finally enriched to waste fluid recycling unit; 其中,S2与S3步骤的顺序可交换或同时进行。Wherein, the sequence of steps S2 and S3 can be exchanged or performed simultaneously. 9.如权利要求8所述的一种血液净化设备体外循环系统的自动预冲方法,其特征在于,所述第一预冲通路和第二预冲通路的构建方法具体为:9. The automatic priming method of the extracorporeal circulation system of a blood purification equipment as claimed in claim 8, wherein the construction method of the first priming passage and the second priming passage is specifically: 将静脉壶(22)串接至所述静脉管路中并将静脉管路的一端连接至所述血室下端接口(11b),将静脉壶(22)串接至所述动脉管路中并将所述动脉管路的一端连接至所述血室上端接口(11a),此时,所述静脉壶(22)、血室下端接口(11b)、血液室(11)、血室上端接口(11a)以及动脉壶(21)形成第一预冲通路,所述透析液下端接口(12b)、透析液室(12)以及透析液上端接口(12a)形成第二预冲通路。The venous pot (22) is connected in series into the venous line and one end of the venous line is connected to the lower end port (11b) of the blood chamber, and the venous pot (22) is connected in series into the arterial line and One end of the arterial pipeline is connected to the upper end port of the blood chamber (11a), at this time, the venous pot (22), the lower end port of the blood chamber (11b), the blood chamber (11), the upper end port of the blood chamber ( 11a) and the arterial jug (21) form a first pre-flushing passage, and the dialysate lower port (12b), the dialysate chamber (12) and the dialysate upper port (12a) form a second pre-flushing passage. 10.如权利要求9所述的一种血液净化设备体外循环系统的自动预冲方法,其特征在于,所述S2具体为:控制所述血液室(11)供液单元为所述第一预冲通路提供第一预冲液,并使得所述第一预冲液以第一流速进入第一预冲通路直至完全充满第一预冲通路,然后使得所述第一预冲液以第二流速在所述第一预冲通路中流动,并最终富集至所述废液回收单元,所述第二流速大于第一流速。10 . The automatic priming method for an extracorporeal circulation system of a blood purification device according to claim 9 , wherein the step S2 is specifically: controlling the blood chamber (11) liquid supply unit to be the first pre-priming method. 11 . The flushing passage provides a first priming liquid, and makes the first priming liquid enter the first priming passage at a first flow rate until the first priming passage is completely filled, and then makes the first priming liquid flow at a second flow rate Flowing in the first pre-flushing passage and finally enriched to the waste liquid recovery unit, the second flow rate is greater than the first flow rate.
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