CN115054833A - Pulse laser therapeutic apparatus and biological information feedback method - Google Patents

Pulse laser therapeutic apparatus and biological information feedback method Download PDF

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Publication number
CN115054833A
CN115054833A CN202210889980.XA CN202210889980A CN115054833A CN 115054833 A CN115054833 A CN 115054833A CN 202210889980 A CN202210889980 A CN 202210889980A CN 115054833 A CN115054833 A CN 115054833A
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mcu
laser
pin
transistor
pulse
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覃祚彪
戴品忠
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/067Radiation therapy using light using laser light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • A61N2005/0602Apparatus for use inside the body for treatment of blood vessels

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The embodiment of the specification discloses a pulse laser therapeutic apparatus and a biological information feedback method. The pulse laser therapeutic instrument includes: MCU, dimming pulse circuit, laser diode and power supply battery. The pulse laser therapeutic apparatus for realizing biofeedback by using probiotic gene codes generates pulse laser with adjusted duty ratio by time length conversion of specific gene codes of healthy people, and simulates to act gene fragment coding information on a human body, thereby not only achieving biological information feedback, but also changing continuous laser irradiation of the existing laser therapeutic apparatus into pulse irradiation, achieving two purposes and improving curative effect.

Description

Pulse laser therapeutic apparatus and biological information feedback method
Technical Field
The application relates to the technical field of medical instruments, in particular to a pulse laser therapeutic apparatus and a biological information feedback method.
Background
In clinical medicine, many diseases are caused by qi stagnation and blood stasis, and the main treatment principle is to improve blood transportation function. Various laser therapeutic instruments popular in the market utilize 650 nanometer low-power laser to continuously irradiate human blood vessels (mainly radial artery and nasal mucosa) and pain parts, and clinical verification proves that the laser therapeutic instruments have the effects of obviously improving blood circulation of tiny blood vessels and being beneficial to health preservation and health care, and are products with strong growth potential in the current medical instrument market. However, when a human body is irradiated with continuous laser light, light fatigue and light adaptation inevitably occur in view of the physiological characteristics of the human body, which impairs the therapeutic effect or is unfavorable for the human health.
Disclosure of Invention
In order to solve the above technical problem, the embodiments of the present specification are implemented as follows:
the embodiment of this specification provides a pulse laser therapeutic instrument, includes: the device comprises an MCU, a dimming pulse circuit, a laser diode and a power supply battery;
the dimming pulse circuit comprises: a first transistor (Q1), a second transistor (Q2), a driving transistor (Q3), a diode (D1), and a plurality of resistors;
a pin 1 of the MCU is a PWM driving pin and outputs PWM square waves with different duty ratios to drive the driving triode (Q3), wherein the driving triode (Q3) is connected with the laser diode;
the pin 2 of the MCU is connected with the power supply battery;
pin 3 of the MCU is connected with the base electrode of a second triode (Q2) through a resistor (R5); the collector of the second triode (Q2) is connected with the grid of the first triode (Q1) through a resistor (R6);
the pin 4 of the MCU is grounded;
5 feet of the pin of the MCU are used for detecting the battery voltage by the ADC and indicating the electric quantity state of the battery through the LED.
Optionally, the method further includes: LED luminotron and button, MCU pin 6, 7, 8 timesharing are used for LED luminotron to drive output foot and the input foot of button.
Optionally, the method further includes: power management chip and USB charging socket, power management chip and USB charging socket are connected, power supply battery with the power management chip is connected.
Optionally, the method further includes: the MCU, the dimming pulse circuit, the laser diode and the power supply battery are arranged on a circuit board, and the circuit board is arranged in the shell.
Optionally, a through hole is formed in the position, corresponding to the laser diode, of the upper cover of the housing; movable keys are arranged on the side surface of the shell corresponding to the positions of the keys; and through holes are formed in the bottom surface of the shell corresponding to the positions of the LED luminous tubes.
Optionally, the MCU is STC8G1K08A, and the power supply battery is a YX 18650 type 7800mWh cylindrical lithium battery.
Optionally, the first transistor (Q1) and the driving transistor (Q3) are PMOS transistors, and the second transistor (Q2) is a silicon transistor.
The embodiment of the present specification provides a biological information feedback method based on a pulsed laser, the method includes:
base coding sequences in the specific DNA segments are stored in a Flash storage unit of the MCU one by one;
sequentially extracting gene codes stored in Flash in microprocessor interruption, and after normalization processing according to DNA base molecular weight, taking a cubic value of the gene codes as gene coding weight to obtain the square wave width output by PWM;
generating a duty ratio for controlling a dimming pulse circuit according to the square wave width, and generating a control voltage for exciting a laser tube according to the duty ratio, wherein the control voltage is converted into a time period quantized according to a gene coding sequence;
and exciting the laser tube by adopting the control voltage to enable the laser to carry DNA information.
Optionally, the step of storing the base coding sequences in the specific DNA fragments in a Flash storage unit of the microprocessor one by one specifically comprises: base pair codes in a specific probiotic DNA fragment of a healthy person are stored in a Flash storage unit of a microprocessor one by one according to the names of four bases, namely adenine, cytosine, guanine and thymine.
Optionally, the square wave width factors output by the PWM are respectively: a-26mS, T-23mS, C-20mS, G-30 mS.
The embodiment of the specification adopts at least one technical scheme which can achieve the following beneficial effects:
the pulse laser therapeutic apparatus for realizing biofeedback by using probiotic gene codes generates pulse laser with adjusted duty ratio by time length conversion of specific gene codes of healthy people, and simulates to act gene fragment coding information on a human body, thereby not only achieving biological information feedback, but also changing continuous laser irradiation of the existing laser therapeutic apparatus into pulse irradiation, achieving two purposes and improving curative effect.
Drawings
The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the application and together with the description serve to explain the application and not to limit the application. In the drawings:
FIG. 1 is a circuit board mounting diagram of the pulse laser therapeutic apparatus provided by the present invention;
FIG. 2 is a schematic diagram of a circuit structure of the pulsed laser therapeutic apparatus according to the present invention;
FIG. 3 is a flow chart of a method for feeding back biological information based on pulsed laser according to the present invention;
FIG. 4 is a logic diagram of the operation of the pulsed laser treatment apparatus;
FIG. 5 is a logic diagram of an interrupt subroutine;
the reference numbers: 1. a laser diode; 2. a power supply battery; 3. pressing a key; 4. an LED light emitting tube; 5. connecting a development system socket; 6. a microprocessor; 7 is a power management chip; 8. a USB charging socket; and 9, driving the triode.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the technical solutions of the present application will be described in detail and completely with reference to the following specific embodiments of the present application and the accompanying drawings. It should be apparent that the described embodiments are only some of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
The technical solutions provided by the embodiments of the present application are described in detail below with reference to the accompanying drawings.
The external surface of the pulse laser therapeutic apparatus provided by the invention is a flat square ABS plastic shell, the whole circuit board is arranged in the shell, and the installation drawing of the circuit board is shown in figure 1. Each electronic component is mounted on the printed circuit board by one-time surface mounting process, and then 14 laser diodes are vertically inserted into the printed circuit board to complete the welding. The side surface of the plastic shell is provided with a convex ring which can bind the instrument to a human body, four corners of the upper cover of the plastic shell are provided with four protruded supporting legs, and when the instrument works, the four legs are close to the human body, thereby being beneficial to heat dissipation when the laser tube emits light.
As shown in fig. 1, the pulse laser treatment apparatus includes: the device comprises a laser diode 1, a power supply battery 2, a key 3, an LED luminous tube 4, a connection development system socket 5, a Microprocessor (MCU)6, a power management chip 7, a USB charging socket 8 and a driving triode 9.
The laser diodes 1 have a size of 6 × 10.5mm and a number of 14, which corresponds to D2-D15 in fig. 2. And the upper cover of the shell is provided with 14 holes corresponding to the laser diode, so that laser is emitted.
The power supply battery 2 is a 3.7V lithium battery and supplies power to the microprocessor 6 and other devices. Specifically, a YX 18650 type 7800mWh cylindrical lithium battery can be selected.
Three keys 3 are provided, corresponding to S1, S2 and S3 of fig. 2, and 3 movable keys are provided on the side of the housing corresponding to the positions of the keys 3.
The number of the LED luminous tubes 4 is 4, and green luminous tubes can be selected. The bottom surface of the shell is provided with 4 holes corresponding to the 4 LED tubes, so that the LED tubes are exposed.
The power management chip 7, corresponding to IC1 in fig. 2, may be of the optional model TP 4056. Which is connected to a USB charging socket 8.
As shown in fig. 2, the pulse laser therapeutic apparatus of the present invention is composed of a Microprocessor (MCU), a light modulation circuit, a plurality of laser diodes and a power supply battery. The microprocessor 6 is an STC8G series single chip microcomputer, an 8051 single chip microcomputer which does not need an external crystal oscillator or external reset and aims at ultra-strong anti-interference, ultra-low price, high speed and low power consumption is adopted, and the STC8G series single chip microcomputer is about 12 times faster than the conventional 8051 single chip microcomputer under the same working frequency.
Specifically, the microprocessor 6 has a model of STC8G1K08A, which corresponds to U1 in fig. 2.
The U1-3 pin is connected with the base of Q2 through a resistor R5, and the collector of Q2 is connected with the grid of Q1 through R6. In the off state, the pin U1-3 is in a high impedance state, the base of the silicon triode Q2 is cut off due to the pull-down of R9, the gate of the PMOS transistor Q1 is cut off due to the pull-up of the resistor R2, and the battery power supply is not turned on.
When the S1 key is pressed, the voltage of the battery is divided by D1, R8 and R9 to turn on Q2, the grid of Q1 is changed into low level to be turned on, U1 is powered on and sets the U1-3 pin as push-pull output to output high level, so that Q2 and Q1 are continuously turned on.
The 6, 7 and 8 pins of the U1 are used for driving output pins of the LEDs and input pins of the keys S1, S2 and S3 in a time sharing mode, when the driving pins of the LEDs are set to be push-pull output, 4 LEDs are driven in a dynamic scanning mode, namely only one LED is lighted at the same time, when the driving pins of the LEDs are used for scanning the S keys, the 6 pins and the 7 pins are set to be pull-up input, and the 8 pins are set to be floating input.
The U1-5 pin is used for an ADC to detect the voltage of the battery and indicates the state of charge of the battery through an LED.
The U1-1 pin is a PWM driving pin, and outputs PWM square waves with different duty ratios to drive the Q3 tube, so that the dimming function of the laser tube is realized, and one laser diode not only carries DNA information, but also adjusts the brightness.
In the power-on state, when a long-press S1 key is scanned, a pin U1-3 outputs low level to cut off Q2, so that Q1 is cut off, and the MCU is powered off.
Wherein, two PMOS triode Q1 select AO3407, Q3 select AO3404, silicon triode Q2 select SS 8050.
Based on the pulse laser therapeutic apparatus, the invention also provides a biological information feedback method based on the pulse laser, as shown in fig. 3, the method comprises the following steps:
step 310: the base coding sequences in the specific DNA segments are stored in a Flash memory unit of a microprocessor one by one.
Specifically, under the condition of connecting with a development system, base pair codes in a special probiotic DNA fragment of a healthy person are stored in a Flash storage unit of a microprocessor one by one according to the names of four bases of adenine (A), cytosine (C), guanine (G) and thymine (T).
Step 320: the gene codes stored in Flash are sequentially extracted in the interrupt of a microprocessor, and after the normalization processing is carried out according to the molecular weight of DNA basic groups, the cubic value of the gene codes is taken as the weight of the gene codes, so as to obtain the square wave width output by PWM.
Step 330: and generating a duty ratio for controlling a dimming pulse circuit according to the square wave width, and generating a control voltage for exciting a laser tube according to the duty ratio, wherein the control voltage is converted into a time period quantized according to a gene coding sequence.
Step 340: and exciting the laser tube by adopting the control voltage to enable the laser to carry DNA information.
In summary, in the initialization of the microprocessor, the timer 1 is configured in an automatic reload timing manner, and the initial value of the timer 1 is calculated according to the selected clock frequency and stored in the corresponding register, so as to ensure that the interrupt occurs every 0.1 second; meanwhile, the timer 2 is started and set to be in a PWM mode, the gene code stored in Flash is written into a PWM pulse duty ratio register of the timer 2 in an interruption subprogram of the timer 1, the gene code sequence is used as the basis of PWM pulse modulation, and a PWM output pin outputs PWM pulse voltage which acts on a pulse modulation circuit and outputs square waves with corresponding widths (see steps 1-4 and 1-14 in figure 4). According to the molecular weight of DNA base: a-313.23, T-304.2, C-289.18 and G-329.21, after normalization treatment, the cubic value is taken as the gene coding weight, and the following results are obtained: the square wave width factors of the PWM output are respectively: a-26mS, T-23mS, C-20mS, G-30 mS. Depending on the patient's needs, the adjustment of the output laser pulse brightness may be selected at a fixed multiple of the PWM output square wave width factor described above (maximum not exceeding 100mS), see steps 1-12 of FIG. 4. Therefore, the brightness (namely the pulse duty ratio) of the output pulse laser can be adjusted (selected), and the coded information of the base pairs in the specific probiotic DNA fragments of healthy people is carried, so that the biofeedback is realized.
The pulse laser therapeutic apparatus for realizing biofeedback by using probiotic gene codes generates pulse laser with adjusted duty ratio by time length conversion of specific gene codes of healthy people, simulates and acts gene fragment coding information on a human body, achieves biological information feedback, changes continuous laser irradiation of the existing laser therapeutic apparatus into pulse irradiation, and improves curative effect.
Based on the above apparatus and method, the following embodiments are provided:
as shown in fig. 4, the method comprises the steps of:
step 1-1: the wait key S1 is pressed.
Step 1-2: the switch is turned on and the instrument is turned on.
Step 1-3: judging whether the key S1 is pressed for a long time, if not, turning to the step 1-16; if yes, turning to the step 1-4;
step 1-4: for the initialization of the single chip microcomputer system, configuring the timer 1 in an automatic reloading timing mode, calculating according to the selected clock frequency to obtain an initial value of the timer 1, and storing the initial value in a corresponding register to ensure that the interruption occurs every 0.1 second; the timer 2 is set to the output mode of the dead-weight PWM, and the timer 1 and the timer 2 are started.
Step 1-5: and judging whether the key S3 is pressed, if not, turning to the step 1-6, and if so, turning to the step 1-10.
1-6: and judging whether the key S2 is pressed, if not, turning to the step 1-7, and if so, turning to the step 1-11.
Step 1-7: and judging whether the key S1 is pressed, if not, turning to the step 1-5, and if so, turning to the step 1-8.
Step 1-8: and judging whether the key S1 is pressed for a long time, if not, turning to the step 1-15, and if so, turning to the step 1-17.
Step 1-9: and setting the working time length, and turning to the step 1-5.
Step 1-10: judging whether laser output is started or not, if not, turning to the step 1-9, and if so, turning to the step 1-13;
step 1-11: judging whether laser output is started or not, if not, turning to the step 1-14, and if so, turning to the step 1-12;
step 1-12: and adjusting the laser brightness, and turning to the step 1-5.
Step 1-13: the laser output is stopped.
Step 1-14: starting laser output and turning to the step 1-5.
Step 1-15: and setting a light emitting mode, and turning to the step 1-5.
Step 1-16: and displaying the current battery power, and turning to the step 1-17.
Step 1-17: and (5) shutting down.
Wherein, the steps 1-5, 1-6 and 1-7 respectively finish setting the working time length, adjusting the laser pulse brightness and setting the light emitting mode (pulse or continuous light emitting).
Fig. 5 is a logic diagram of the interrupt subroutine, as shown in fig. 5, which specifically includes:
step 2-1: judging whether laser output is started or not, if so, jumping to the step 2-2, and if not, exiting interruption;
step 2-2: reading gene coding sequences from Flash;
step 2-3: writing the extracted gene coding sequence into a PWM duty ratio register of a timer 2 according to the quantization weight;
step 2-4: the PWM output pin outputs PWM pulses according to the PWM duty ratio, the laser driver outputs corresponding driving voltage according to the PWM pulses, and the brightness of the laser tube is adjusted, so that DNA information of healthy people is carried in laser.
It should also be noted that the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
The application may be described in the general context of computer-executable instructions, such as program modules, being executed by a computer. Generally, program modules include routines, programs, objects, components, data structures, etc. that perform particular tasks or implement particular abstract data types. The application may also be practiced in distributed computing environments where tasks are performed by remote processing devices that are linked through a communications network. In a distributed computing environment, program modules may be located in both local and remote computer storage media including memory storage devices.
The embodiments in the present specification are described in a progressive manner, and the same and similar parts among the embodiments are referred to each other, and each embodiment focuses on the differences from the other embodiments. In particular, for the system embodiment, since it is substantially similar to the method embodiment, the description is simple, and for the relevant points, reference may be made to the partial description of the method embodiment.
The above description is only an example of the present application and is not intended to limit the present application. Various modifications and changes may occur to those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the scope of the claims of the present application.

Claims (10)

1. A pulsed laser treatment apparatus, comprising: the device comprises an MCU, a dimming pulse circuit, a laser diode and a power supply battery;
the dimming pulse circuit comprises: a first transistor (Q1), a second transistor (Q2), a driving transistor (Q3), a diode (D1), and a plurality of resistors;
a pin 1 of the MCU is a PWM driving pin and outputs PWM square waves with different duty ratios to drive the driving triode (Q3), wherein the driving triode (Q3) is connected with the laser diode;
the pin 2 of the MCU is connected with the power supply battery;
pin 3 of the MCU is connected with the base electrode of a second triode (Q2) through a resistor (R5); the collector of the second triode (Q2) is connected with the grid of the first triode (Q1) through a resistor (R6);
the pin 4 of the MCU is grounded;
pin 5 of the MCU is used for the ADC to detect the battery voltage.
2. The pulsed laser treatment instrument of claim 1, further comprising: LED luminotron and button, MCU pin 6, 7, 8 timesharing are used for LED luminotron to drive output foot and the input foot of button.
3. The pulsed laser treatment instrument of claim 1, further comprising: power management chip and USB charging socket, power management chip and USB charging socket are connected, power supply battery with the power management chip is connected.
4. The pulsed laser treatment instrument of claim 2, further comprising: the MCU, the dimming pulse circuit, the laser diode and the power supply battery are installed on a circuit board, and the circuit board is installed in the shell.
5. The pulsed laser therapeutic instrument of claim 4, wherein the upper cover of the housing is provided with a through hole at a position corresponding to the laser diode; movable keys are arranged on the side surface of the shell corresponding to the positions of the keys; and through holes are formed in the bottom surface of the shell corresponding to the positions of the LED luminous tubes.
6. The pulsed laser therapeutic device of claim 1, wherein the MCU is STC8G1K08A, and the power supply battery is YX 18650 7800mWh cylindrical lithium battery.
7. The pulsed laser treatment device of claim 1, wherein the first transistor (Q1) and the driving transistor (Q3) are PMOS transistors and the second transistor (Q2) is a silicon transistor.
8. A biological information feedback method based on pulse laser is characterized by comprising the following steps:
base coding sequences in the specific DNA segments are stored in a Flash storage unit of the MCU one by one;
sequentially extracting gene codes stored in Flash in microprocessor interruption, and after normalization processing according to DNA base molecular weight, taking a cubic value of the gene codes as gene coding weight to obtain the square wave width output by PWM;
generating a duty ratio for controlling a dimming pulse circuit according to the square wave width, and generating a control voltage for exciting a laser tube according to the duty ratio, wherein the control voltage is converted into a time period quantized according to a gene coding sequence;
and exciting the laser tube by adopting the control voltage to enable the laser to carry DNA information.
9. The method of claim 8, wherein the base coding sequences in the specific DNA fragments are stored in a Flash memory unit of a microprocessor one by one, and the method comprises: base pair codes in specific probiotic DNA segments of healthy people are stored in a Flash storage unit of a microprocessor one by one according to the names of four bases, namely adenine, cytosine, guanine and thymine.
10. The method of claim 8, wherein the square wave width factors of the PWM output are: a-26mS, T-23mS, C-20mS, G-30 mS.
CN202210889980.XA 2022-07-27 2022-07-27 Pulse laser therapeutic apparatus and biological information feedback method Withdrawn CN115054833A (en)

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Application Number Priority Date Filing Date Title
CN202210889980.XA CN115054833A (en) 2022-07-27 2022-07-27 Pulse laser therapeutic apparatus and biological information feedback method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210889980.XA CN115054833A (en) 2022-07-27 2022-07-27 Pulse laser therapeutic apparatus and biological information feedback method

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