CN114569126A

CN114569126A - Trace sampling tube and blood sampling method thereof

Info

Publication number: CN114569126A
Application number: CN202210463452.8A
Authority: CN
Inventors: 谢伟; 杨恒歌
Original assignee: Shenzhen Dymind Biotechnology Co Ltd
Current assignee: Shenzhen Dymind Biotechnology Co Ltd
Priority date: 2022-04-29
Filing date: 2022-04-29
Publication date: 2022-06-03
Anticipated expiration: 2042-04-29
Also published as: CN114569126B

Abstract

The application discloses a micro-sampling tube and a blood sampling method thereof. The micro sampling tube includes: the blood sampling device comprises a tube body, a tube cover and a blood sampling assembly, wherein the tube body is provided with an accommodating cavity which is used for accommodating a sample; the tube cover is arranged at the opening of the tube body, a through hole communicated with the accommodating cavity is formed in the tube cover, an elastic film layer for sealing the through hole is arranged in the through hole, a cutting seam penetrating through the through hole is formed in the elastic film layer, and the blood sampling assembly is used for collecting a sample and injecting the sample into the accommodating cavity; one end of the blood sampling assembly penetrates through the elastic film layer and extends into the accommodating cavity, and the other end of the blood sampling assembly is positioned outside the tube cover; when one end of the blood sampling assembly extends into the tube body, the blood sampling assembly is in sealing fit with the elastic membrane layer. The utility model provides a micro-sampling pipe's simple structure can the convenience of customers one-hand operation through institutional advancement, reduces the manual operation process, improves blood sampling efficiency, and can reduce sample biological pollution's risk.

Description

Trace sampling tube and blood sampling method thereof

Technical Field

The application relates to the technical field of medical instruments, in particular to a micro-sampling tube and a blood sampling method thereof.

Background

During sample analysis, a sample is first collected. For example, blood sample testing requires the collection of a certain amount of sample from a patient. Two common blood sampling methods are available: venous blood and peripheral blood were collected. The venous blood sampling mode is suitable for adult patients; in the case of infants, children, or critically ill patients, it is sometimes difficult to collect blood by intravenous means, and in such cases, peripheral blood is often collected.

The peripheral blood collection at least comprises the following steps: (1) a doctor is required to select a micro sampling tube and a capillary tube which are not sampled, and a tube cover of the micro sampling tube is taken down; (2) holding the capillary tube to draw peripheral blood into the capillary tube; (3) a doctor needs to operate by matching two hands, holds the saccule by one hand and holds the capillary tube by the other hand, and inserts the saccule into one end of the capillary tube, which is not contacted with peripheral blood; (4) the method comprises the following steps that a blood sample is injected into a micro-sampling tube by holding a capillary tube with one hand, in the process, in order to inject peripheral blood into the micro-sampling tube, a doctor needs to operate by matching two hands, and the micro-sampling tube is supported by the other hand of the doctor; (5) after the peripheral blood injection is completed, the tube cap is covered back to the opening of the micro sampling tube, and the used capillary tube is discarded. Therefore, the process of peripheral blood sampling is complicated and the trace blood collection efficiency is low due to the structural arrangement of the current trace sampling tube.

Disclosure of Invention

The application mainly aims to provide a micro sampling tube and a blood sampling method thereof, and aims to solve the technical problems that in the prior art, the structure of the micro sampling tube is arranged to cause the blood sampling process to be more complicated, and the micro blood collection efficiency is lower.

In order to solve the above problems, the present application provides a micro sampling tube, comprising: the blood sampling device comprises a tube body, a tube cover and a blood sampling assembly, wherein the tube body is provided with an accommodating cavity which is used for accommodating a sample; the tube cover is arranged at the opening of the tube body, a through hole communicated with the accommodating cavity is arranged on the tube cover, an elastic film layer for sealing the through hole is arranged in the through hole, and a cutting seam penetrating through the through hole is arranged on the elastic film layer; the blood sampling assembly is used for collecting a sample and injecting the sample into the accommodating cavity; one end of the blood sampling assembly penetrates through the elastic membrane layer and extends into the accommodating cavity, and the other end of the blood sampling assembly is positioned outside the tube cover; when one end of the blood sampling assembly extends into the tube body, the blood sampling assembly is in sealing fit with the elastic membrane layer.

Further, the elastic film layer is arranged at one end, close to the opening of the tube body, of the through hole, or the elastic film layer is arranged at the middle position of the through hole, or the elastic film layer is arranged at one end, far away from the opening of the tube body, of the through hole.

Further, the cutting seam comprises a first sub cutting seam and a second sub cutting seam which are arranged in an intersecting mode; or the cutting seam is arranged in a straight line shape, or the cutting seam is arranged in a curve shape.

Further, the blood collection assembly includes: the capillary tube operating handle is detachably connected with the tube cover and is arranged on one side of the tube cover, which is far away from the tube body; the capillary tube is fixed on the capillary tube operating handle, one end of the capillary tube penetrates through the cutting joint and extends into the accommodating cavity, and the capillary tube is in sealing fit with the elastic film layer; the other end of the capillary tube protrudes out of the outer surface of the capillary tube operating handle.

Furthermore, the blood sampling assembly also comprises a capillary tube cover which is covered on the capillary tube operating handle and is used for sealing the tube body; the capillary tube cover is arranged at an interval with the other end of the capillary tube.

Further, the inside of body is in the negative pressure state, and when the one end of the capillary that has inhaled the sample was placed in the holding intracavity to automatic sample injection to the microsampling pipe.

Further, the inner diameter of the bottom of the pipe body is gradually reduced in the direction away from the opening of the pipe body.

Further, the minimum inner diameter of the bottom of the pipe body is greater than or equal to 2 mm.

Further, the tube cap includes the inner cup and encloses the enclosing cover of locating the inner cup outside, and the inner cup adopts elastic material, and the enclosing cover is used for finalizing the design to the inner cup, and the through-hole link up sets up on the inner cup, and a side end face that the body was kept away from to the enclosing cover is provided with the sealing film, and the sealing film is used for sealing the holding chamber.

Further, the microsampling tube is also used to collect venous blood.

In order to solve the above problem, the present application further provides a method for collecting blood from a micro sampling tube, where the method for collecting blood from a micro sampling tube according to any of the above embodiments includes: collecting a sample to be detected through a blood collecting component of the micro-sampling tube; injecting a sample to be tested into the accommodating cavity through the blood sampling assembly; after the sample to be detected is injected into the accommodating cavity, the tight fit between the blood sampling assembly and the elastic film layer is removed, so that the elastic film layer is restored to the natural state.

Further, the interior of the tube body is in a negative pressure state.

Furthermore, the blood sampling assembly comprises a capillary tube operating handle, a capillary tube and a capillary tube cover, wherein the capillary tube operating handle is detachably connected with the capillary tube cover and is arranged on one side of the capillary tube cover, which is far away from the tube body; the capillary tube is fixed on the capillary tube operating handle, and one end of the capillary tube penetrates through the cutting joint and extends into the accommodating cavity; the other end of the capillary tube protrudes out of the outer surface of the capillary tube operating handle; the capillary tube cover is arranged on the capillary tube operating handle and used for sealing the tube body; the blood sampling subassembly through the microsampling pipe gathers the sample that awaits measuring, still includes: the connection between the capillary tube cover and the capillary tube operating handle is released; and collecting a sample to be detected by using the other end of the capillary tube through negative pressure in the tube body.

Furthermore, the blood sampling assembly comprises a capillary tube operating handle, a capillary tube and a capillary tube cover, wherein the capillary tube operating handle is detachably connected with the capillary tube cover and is arranged on one side of the capillary tube cover, which is far away from the tube body; the capillary tube is fixed on the capillary tube operating handle, and one end of the capillary tube penetrates through the cutting joint and extends into the accommodating cavity; the other end of the capillary tube protrudes out of the outer surface of the capillary tube operating handle; the capillary tube cover is arranged on the capillary tube operating handle and used for sealing the tube body, and the capillary tube cover and the other end of the capillary tube are arranged at intervals; the blood sampling subassembly through the microsampling pipe gathers the sample that awaits measuring, still includes: releasing the connection between the capillary tube operating handle and the tube cover; the close contact between the capillary tube and the elastic film layer is released, and the elastic film layer is restored to a natural state; collecting a sample to be detected through one end of a capillary; one end of the capillary tube is extended into the accommodating cavity again, and the capillary tube operating handle is connected with the tube cover.

Further, pour into the holding intracavity through the sample collection subassembly with the sample that awaits measuring, still include: the sample to be detected collected in the capillary is automatically injected into the accommodating cavity through the negative pressure in the tube body.

Further, pour into the holding intracavity through the sample collection subassembly with the sample that awaits measuring, still include: releasing the connection between the capillary tube cover and the capillary tube operating handle; the other end of the capillary tube is connected with a saccule; the sample to be detected collected in the capillary is injected into the accommodating cavity by the negative pressure in the tube body and the pressure provided by the saccule.

Has the advantages that: in contrast to the prior art, the present application provides a microsampling tube comprising: the blood sampling device comprises a tube body, a tube cover and a blood sampling assembly, wherein the tube body is provided with an accommodating cavity which is used for accommodating a sample; the pipe cap is arranged at the opening of the pipe body and used for sealing the accommodating cavity. The tube cover is provided with a through hole communicated with the containing cavity, an elastic film layer for sealing the through hole is arranged in the through hole of the tube cover, a cutting seam penetrating through the through hole is arranged on the elastic film layer, the blood sampling assembly is used for collecting a sample, and one end of the blood sampling assembly penetrates through the cutting seam and injects the sample into the containing cavity. This application combines blood sampling subassembly and micro-sampling pipe, reduces the centre of sampling and prepares the process, and in addition, micro-sampling pipe need not to uncap and close the lid operation at the in-process of sampling, and this application can simplify manual operation's process through the structure of improving micro-sampling pipe, improves sampling efficiency, and can reduce sample biological pollution's risk.

Drawings

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.

FIG. 1 is a schematic diagram illustrating the construction of one embodiment of a microsampling tube as provided herein;

FIG. 2 is a schematic diagram of the construction of one embodiment of the tube cover of FIG. 1;

FIG. 3 is a schematic top view of an embodiment of the tube cover shown in FIG. 2;

FIG. 4 is a schematic view of a portion of the micro sampling tube of FIG. 1;

FIG. 5 is a schematic flow diagram illustrating one embodiment of a method of drawing blood from a microsampling tube as provided herein;

FIG. 6 is a flowchart illustrating an embodiment of step S11 in FIG. 5;

FIG. 7 is a schematic flow chart diagram illustrating another embodiment of step S11 in FIG. 5;

FIG. 8 is a flowchart illustrating an embodiment of step S12 in FIG. 5.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. It is to be understood that the specific embodiments described herein are merely illustrative of the application and are not limiting of the application. It should be further noted that, for the convenience of description, only some of the structures related to the present application are shown in the drawings, not all of the structures. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

The terms "first" and "second" in this application are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the feature. In the description of the present application, "plurality" means at least two, e.g., two, three, etc., unless explicitly specifically limited otherwise. All directional indications (such as up, down, left, right, front, and rear … …) in the embodiments of the present application are only used to explain the relative positional relationship between the components, the movement, and the like in a specific posture (as shown in the drawings), and if the specific posture is changed, the directional indication is changed accordingly. Furthermore, the terms "include" and "have," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.

The application provides a neotype trace sampling pipe, and this trace sampling pipe passes through the operation process that the institutional advancement can effectual simplification sample, reduces manual operation's step, improves the efficiency of blood sampling, alleviates blood sampling worker's work burden, and can reduce sample biological pollution's risk.

Referring to fig. 1, fig. 1 is a schematic structural diagram of an embodiment of a micro sampling tube 10 provided in the present application, which includes a tube body 11, a tube cap 12 covering the tube body 11, and a blood collection assembly 13.

The tube 11 is formed with an accommodating chamber 111, and the accommodating chamber 111 is used for accommodating a sample. The sample may be peripheral blood or venous blood, etc. In other embodiments, the sample may also be a body fluid such as saliva, sweat, or the like.

The tube cover 12 covers the opening of the tube 11 and is used for sealing the accommodating cavity 111. The cap 12 is detachably connected to the body 11.

Referring to fig. 2, fig. 2 is a schematic structural diagram of an embodiment of the tube cover in fig. 1, a through hole 121 communicating with the accommodating cavity 111 is formed on the tube cover 12, and one end of the blood collection assembly 13 can extend into the accommodating cavity 111 through the through hole 121.

Referring to fig. 3, fig. 3 is a schematic top view of the tube cap shown in fig. 2, an elastic film 122 for covering the through hole 121 is disposed in the through hole 121 of the tube cap 12, and a slit 123 penetrating the accommodating cavity 111 is disposed on the elastic film 122. One end of the lancet assembly 13 passes through the slit 123 and the through hole 121 to protrude into the receiving chamber 111, thereby injecting a sample into the receiving chamber 111. It can be understood that the elastic film 122 needs to be fixed with the tube cap 12, so as to prevent the elastic film 122 from falling off when one end of the blood sampling assembly 13 or the sampling needle is inserted, and avoid the sample from being thrown out when the subsequent trace samples are mixed uniformly.

Further, the elastic film 122 may be a flexible film such as a silicone film or a rubber film. After the sample is collected by the blood collection assembly 13, the sample is injected into the accommodating chamber 111. After the blood collection assembly 13 is pulled out (i.e., the tight fit between the blood collection assembly 13 and the elastic film 122 is released), the elastic film 122 is restored to a natural state, and the sample in the tube 11 does not flow out. In addition, when an automatic sample introduction test is performed, the sampling needle of the sample analyzer easily penetrates through the elastic film layer 122, so that the abrasion of the sampling needle is reduced.

Further, the blood collection assembly 13 is used for collecting a sample and injecting the sample into the accommodating cavity 111, specifically, one end of the blood collection assembly 13 may pass through the slit 123 on the elastic film layer 122 and extend into the accommodating cavity 111, and the other end of the blood collection assembly 13 is located outside the tube cover 12, so as to facilitate installation and detachment of the blood collection assembly 13; when one end of the blood sampling assembly 13 extends into the tube body 11, the blood sampling assembly 13 is in sealing fit with the elastic film layer 122, so that the risk of contamination of a sample in the tube body 11 is reduced.

In one embodiment, as shown in FIG. 5, the micro-sampling tube 10 may be used in a blood collection method comprising:

s11: and collecting a sample to be detected through a blood collecting component of the micro-sampling tube.

S12: and injecting the sample to be tested into the accommodating cavity through the blood sampling assembly.

S13: after the sample to be detected is injected into the accommodating cavity, the tight fit between the blood sampling assembly and the elastic film layer is released, so that the elastic film layer is restored to a natural state.

Specifically, the user can directly collect a sample through the blood collection assembly 13, inject the collected sample into the accommodating cavity 111, and then pull out the blood collection assembly 13, so that the elastic membrane 122 is restored to a natural state, and thus, the accommodating cavity 111 is sealed.

The micro-sampling tube 10 is simple in structure, the micro-sampling tube 10 is provided with the blood sampling assembly 13, and the middle preparation process of sample collection is reduced. In addition, when the micro blood collection tube in the prior art is used for sampling, a user needs to open and close the cover, and needs to perform matching operation with both hands of the user, specifically as described in the background art. The micro-sampling tube 10 facilitates the one-hand operation of a user, and when the sample is sampled, the user does not need to open and close the cover, so that the process of manual operation is simplified, the sampling efficiency is improved, and the risk of biological pollution of the sample can be reduced.

Further, as shown in fig. 2, the tube cover 12 includes an inner cover 124 and an outer cover 125, the outer cover 125 is disposed around the inner cover 124, and the outer cover 125 is used for supporting and shaping the inner cover 124. The inner cover 124 may be formed of a soft, deformable, resilient material such as rubber or silicone. The outer cover 125 may be a non-deformable plastic housing.

The through hole 121 is formed through the inner cover 124, and preferably, the through hole 121 may be formed in the middle of the inner cover 124. The diameter of the through hole 121 may be 3-5mm, for example, the diameter of the through hole 121 may be 3mm, 3.5mm, 4mm, or 5mm, etc.

Further, the elastic film 122 is disposed in the middle of the through hole 121, or the elastic film 122 is disposed at one end of the through hole 121 close to the opening of the tube 11. Preferably, the elastic film 122 is disposed at an end of the through hole 121 away from the opening of the tube 11, and this arrangement can facilitate the fixing of the elastic film 122. That is, the elastic film layer 122 may be located at the upper part, the middle part or the bottom part of the through hole 121, and may be selected according to actual conditions.

The slits 123 may be provided at the middle of the elastic film layer 122. The slit 123 is used to pass a capillary or sampling needle. In one embodiment, as shown in FIG. 3, the slit 123 may include a first sub-slit (not shown) and a second sub-slit (not shown) intersecting each other, for example, the first sub-slit and the second sub-slit are arranged in a cross shape, and one end of the blood collection assembly 13 may extend into the receiving cavity 111 through the intersection point of the first sub-slit and the second sub-slit. In another embodiment, the slits 123 may also be in a straight line or curved.

Further, as shown in fig. 2, a sealing film 126 is provided on an end surface of the outer cap 125 on a side away from the tube body 11, that is, a sealing film is sealed on an upper end surface of the tube cap 12. The sealing film 126 may be an aluminum film or other material film, and the sealing film 126 may be easily torn off. The sealing film 126 is used for sealing the accommodating cavity 111.

When the micro sampling tube 10 of this embodiment is used, tear the sealing film 126 outside the tube cap 12 of the micro sampling tube 10, collect a sample through the blood sampling assembly 13, and inject the sample into the accommodating cavity 111, after the sample injection is finished, extract the blood sampling assembly 13, and the elastic film layer 122 recovers to a natural state to prevent the sample in the accommodating cavity 111 from flowing out.

Further, the outer dimensions of the micro-sampling tube 10 may be consistent with the outer dimensions of an iv tube. Specifically, the diameter and height of the micro-sampling tube 10 may be the same as the intravenous blood collection tube. For example, as shown in FIG. 4, the total height h2 of the microsampling tube 10 may correspond to the height of a typical IV tube, the height after removing the tube cap 12 may be 72-78mm, and the height after covering the tube cap 12 may be about 80-86 mm; the diameter d of the microsampling tube 10 ranges from 10 to 16 mm. The bottom of the tube 11 is formed with a sample collecting part 112, and the bottom of the sample collecting part 112 has a height h1 of 65mm to 75mm, for example, h1 may be 70mm, from the top surface of the cap 12, which can maintain the same height of the lower needle as the intravenous blood collection tube. By this way, the micro-sampling tube 10 can share the original sampling device of the venous blood sampling tube for sampling, thereby realizing automatic sampling. That is, the micro-sampling tube 10 can be put on the sample holder of the iv tube like the iv tube, and the original iv tube holder can hold the blood collection tube containing the micro blood and the iv blood at the same time.

Further, among the prior art, adopt trace blood can choose for use and adopt the dedicated sampling pipe of trace blood, adopt vein blood can choose for use and adopt the dedicated sampling pipe of vein blood, because the trace sampling pipe 10 of this application can compatible adopt trace blood and vein blood, to operators such as doctors, need not the operator to go the type of discerning the sampling pipe, through using this application trace sampling pipe 10 can realize the sampling to trace blood or vein blood.

In addition, among the prior art, because the difference of adopting the dedicated sampling pipe of trace blood and the dedicated sampling pipe of vein blood, the needle setting distance when sample analyzer's sampling needle punctures the sampling pipe is different, therefore, before the needle setting, the type of sampling pipe needs to be discerned earlier to equipment, because the overall dimension of the trace sampling pipe 10 of this application can keep unanimous with the appearance of vein blood sampling pipe, the trace sampling pipe 10 diameter and the height of this application can be the same with vein blood sampling pipe, to equipment, need not to discern the sampling pipe and then judge the needle setting degree of depth, therefore, can effectively improve the efficiency of the follow-up detection of sample analyzer, save sample analyzer's energy consumption.

Preferably, the sample collecting part 112 may be in an inverted cone shape, that is, the inner diameter of the bottom of the tube 11 is gradually reduced along the direction away from the opening of the tube 11, so as to gather the sample as much as possible and facilitate the collection of the micro sample.

Further, the minimum inner diameter of the bottom of the tube body 11 is greater than or equal to 2mm, and by the arrangement, the liquid level of the sample collected by the micro-sampling tube 10 is higher than the lowest point of the bottom of the tube body 11, so that the sampling needle can more easily extend below the liquid level of the sample of the tube body 11 and suck the sample of the tube body 11 during subsequent automatic sample feeding, and the utilization rate of the sample is improved.

The microsampling tube 10 of the present application can be used to sample both trace blood and venous blood. Alternatively, the interior and exterior of the body 11 of the micro sampling tube 10 may be in a state of pressure equilibrium, or the interior of the body 11 of the micro sampling tube 10 may be in a state of negative pressure. The selection can be specifically carried out according to the actual use requirement.

Further, as shown in fig. 1, in one particular embodiment, the blood collection assembly 13 includes: a capillary operating handle 14, a capillary 15 and a capillary cover 16. The capillary operating handle 14 is detachably connected to the tube cap 12, and is disposed on a side of the tube cap 12 away from the tube 11. Capillary 15 is fixed in capillary operating handle 14, and one end of capillary 15 runs through lance 123 to stretch into holding chamber 111, and capillary 15 and elasticity rete 122 are sealed to cooperate, in order to seal holding chamber 111. In the above embodiment, the other end of capillary 15 may protrude from the outer surface of capillary handle 14 to facilitate mounting of a balloon at the other end of capillary 15.

The capillary cover 16 covers the capillary operation handle 14 and seals the tube body 11. In this embodiment, the capillary cover 16 is covered on the capillary operation handle 14 and can be easily removed. Further, the capillary cover 16 and the other end of the capillary 15 are disposed at an interval, that is, a gap is left between the capillary cover 16 and the other end of the capillary 15, so that the internal and external pressures of the capillary 15 are balanced, and a sample is conveniently sucked into one end of the capillary 15.

In one embodiment, as shown in fig. 6, when the interior of the tube 11 is under negative pressure, the blood collection assembly 13 of the micro-sampling tube 10 collects the sample to be tested as follows:

s111: and releasing the connection between the capillary tube cover and the capillary tube operating handle.

S112: and collecting a sample to be detected by using the other end of the capillary tube through negative pressure in the tube body.

In the above embodiment, the micro-sampling tube 10 directly uses the negative pressure in the capillary 15 and the tube 11 of the blood collection assembly 13 to automatically sample the blood from the human body during the sampling process. During the heparin tube sampling among the prior art, need prepare the blood sampling subassembly in addition, and when the sampling, need open and close the operation of tube cap, micro-sampling pipe 10 combines with blood sampling subassembly 13 in this application, can reduce the centre preparation process of gathering the sample, and need not to open and close the operation of tube cap 12 when sampling, during the sampling, also need not to extract capillary 15, user's one-hand operation can be accomplished and gather micro-sampling pipe from the human body via the blood sampling subassembly with micro-blood, convenience of customers's operation, simplify manual operation's process, the efficiency of sampling is improved.

In another embodiment, the blood collection assembly 13 may be removed from the cap 12 by capillary-operated handle 14 before sampling the sample. Specifically, as shown in fig. 7, the step of collecting the sample to be tested through the blood collection assembly 13 of the micro sampling tube 10 may further include:

s101: and releasing the connection between the capillary tube operating handle and the tube cover.

S102: the close contact between the capillary and the elastic film layer is released, and the elastic film layer is restored to the natural state.

S103: the sample to be measured is collected through one end of the capillary.

S104: one end of the capillary tube is extended into the accommodating cavity again, and the capillary tube operating handle is connected with the tube cover.

In this embodiment, the blood collection unit 13 may be pulled out by the capillary operation handle 14, and after sampling is performed through one end of the capillary 15, one end of the capillary 15 is inserted into the tube body 11. This embodiment combines together capillary 15 and micro sampling pipe 10, can reduce the middle preparation process that micro sampling pipe 10 gathered the sample, and when the sampling, as long as take out capillary 15 through capillary operating handle 14 can, need not to open and close tube cap 12, simplify manual operation's process, improve the efficiency of sampling.

Further, in a specific embodiment, when the tube 11 is in a negative pressure state, as shown in fig. 8, the step of injecting the sample to be tested into the accommodating cavity 111 through the blood sampling assembly 13 includes:

s121: and releasing the connection between the capillary tube cover and the capillary tube operating handle.

S122: the other end of the capillary is connected with a saccule.

S123: the sample to be detected collected in the capillary is injected into the accommodating cavity by the negative pressure in the tube body and the pressure provided by the saccule.

After sampling, the blood collection unit 13 may remove the capillary cap 16 of the capillary operating handle 14 to expose the other end of the capillary 15, and insert a balloon (not shown) into the other end of the capillary 15, wherein the balloon may be a disposable balloon or a reusable balloon. The sample in the capillary 15 is quickly injected into the accommodating cavity 111 by the negative pressure in the tube body 11 and pressing the balloon. The used capillary 15 and its capillary-operated handle 14 are removed from the cap 12 and discarded. In this embodiment, the negative pressure and the balloon are simultaneously utilized to enable the sample to be measured in the capillary 15 to be rapidly injected into the accommodating cavity 111, so that the sampling efficiency is improved.

In another embodiment, the step of injecting the sample to be tested into the accommodating cavity 111 through the blood collecting assembly 13 may further include: the sample to be measured collected in the capillary 15 is automatically injected into the accommodating cavity 111 by the negative pressure in the tube body 11. Through this kind of mode, need not additionally to use extrusion subassemblies such as sacculus, practice thrift the material cost of blood sampling process, and in the sample automatic injection holding chamber 111, need not manual operation, simplify the manual operation process, the user of being convenient for uses.

It can be understood that the pressure in the tube body 11 can be balanced, and in this state, the sample to be measured in the capillary 15 can be injected into the accommodating cavity 111 through the balloon, so that the requirement on the micro-sampling tube 10 is reduced, and the production cost is reduced.

The micro-sampling tube 10 is combined with the capillary 15, so that the intermediate preparation process of collecting samples can be reduced, the sampling efficiency is improved, and the risk of biological pollution of the samples can be reduced.

In conclusion, the micro-sampling tube 10 of the above embodiment has a simple structure, and the micro-sampling tube 10 is combined with the blood sampling assembly 13, so that the middle preparation process of collecting samples can be reduced, the operations of opening and closing the cover can be reduced during sample sampling, the process of manual operation is simplified, the sampling efficiency is improved, and the risk of biological pollution of the samples can be reduced.

The principle and the implementation of the present application are explained herein by applying specific examples, and the above description of the embodiments is only used to help understand the method and the core idea of the present application; meanwhile, for a person skilled in the art, according to the idea of the present application, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present application.

Claims

1. A micro-sampling tube, comprising:

the tube body is provided with an accommodating cavity which is used for accommodating a sample;

the pipe cover is arranged at the opening of the pipe body in a covering mode, a through hole communicated with the accommodating cavity is formed in the pipe cover, an elastic film layer for sealing the through hole is arranged in the through hole, and a cutting seam penetrating through the through hole is formed in the elastic film layer;

the blood sampling assembly is used for collecting the sample and injecting the sample into the accommodating cavity; one end of the blood sampling assembly penetrates through the elastic membrane layer and extends into the accommodating cavity, and the other end of the blood sampling assembly is positioned outside the tube cover; when one end of the blood sampling assembly is positioned in the tube body, the blood sampling assembly is in sealing fit with the elastic film layer.

2. The micro sampling tube of claim 1, wherein the elastic film layer is disposed at an end of the through hole near the opening of the tube body, or,

the elastic film layer is arranged in the middle of the through hole, or,

the elastic film layer is arranged at one end, away from the opening of the tube body, of the through hole.

3. The micro sampling tube of claim 1, wherein said slit comprises a first sub slit and a second sub slit arranged to intersect; or,

the cutting seams are arranged in a straight line shape, or,

the cutting seams are arranged in a curve.

4. The microsampling tube of claim 1, wherein the blood collection assembly comprises:

the capillary tube operating handle is detachably connected with the tube cover and is arranged on one side of the tube cover, which is far away from the tube body; and

the capillary tube is fixed on the capillary tube operating handle, one end of the capillary tube penetrates through the cutting seam and extends into the accommodating cavity, and the capillary tube is in sealing fit with the elastic film layer; the other end of the capillary tube protrudes out of the outer surface of the capillary tube operating handle.

5. The micro sampling tube of claim 4, wherein the blood collection assembly further comprises a capillary cap disposed on the capillary handle, the capillary cap being configured to seal the tube body; the capillary tube cover and the other end of the capillary tube are arranged at intervals.

6. The micro sampling tube according to claim 4 or 5, wherein the interior of the tube body is under negative pressure, and when one end of the capillary tube, which is sucked with the sample, is placed in the accommodating chamber, the sample is automatically injected into the micro sampling tube.

7. The microsampling tube of claim 1, wherein the inner diameter of the bottom of the tube decreases in a direction away from the opening of the tube.

8. The microsampling tube of claim 7, wherein the minimum inner diameter of the bottom of the tube body is greater than or equal to 2 mm.

9. The micro-sampling tube according to any one of claims 1 to 3, wherein the tube cap comprises an inner cap and an outer cap surrounding the inner cap, the inner cap is made of an elastic material, the outer cap is used for shaping the inner cap, the through hole is arranged on the inner cap in a penetrating manner, a sealing film is arranged on the end surface of the outer cap, which is far away from the tube body, on one side, and the sealing film is used for sealing the accommodating cavity.

10. The microsampling tube of claim 6, wherein the microsampling tube is further used to collect venous blood.

11. A method of sampling blood from a micro sampling tube, the method comprising:

collecting a sample to be detected through a blood collecting component of the micro-sampling tube;

injecting the sample to be tested into the accommodating cavity through the blood sampling assembly;

after the sample to be detected is injected into the accommodating cavity, the tight fit between the blood sampling assembly and the elastic film layer is removed, so that the elastic film layer is restored to a natural state.

12. The method of claim 11, wherein the tube is under negative pressure.

13. The method of claim 12, wherein the blood collection assembly comprises a capillary-operated handle, a capillary tube and a capillary cap, the capillary-operated handle being detachably connected to the capillary cap and disposed on a side of the capillary cap away from the tube body; the capillary tube is fixed on the capillary tube operating handle, and one end of the capillary tube penetrates through the cutting seam and extends into the accommodating cavity; the other end of the capillary tube protrudes out of the outer surface of the capillary tube operating handle; the capillary tube cover is arranged on the capillary tube operating handle and used for sealing the tube body;

through the blood sampling subassembly collection sample that awaits measuring of microsampling pipe still includes:

releasing the connection of the capillary cover and the capillary operation handle;

and collecting the sample to be detected by utilizing the other end of the capillary tube through the negative pressure in the tube body.

14. The method of claim 12, wherein the blood collection assembly comprises a capillary-operated handle, a capillary tube and a capillary cap, the capillary-operated handle is detachably connected to the capillary cap and is disposed on a side of the capillary cap away from the tube body; the capillary tube is fixed on the capillary tube operating handle, and one end of the capillary tube penetrates through the cutting seam and extends into the accommodating cavity; the other end of the capillary tube protrudes out of the outer surface of the capillary tube operating handle; the capillary tube cover is arranged on the capillary tube operating handle and used for sealing the tube body, and the capillary tube cover and the other end of the capillary tube are arranged at intervals;

through the blood sampling subassembly of microsampling pipe gathers the sample that awaits measuring, still includes:

releasing the connection between the capillary operating handle and the tube cover;

releasing the close contact between the capillary tube and the elastic film layer, and enabling the elastic film layer to recover to a natural state;

collecting the sample to be detected through one end of the capillary;

and one end of the capillary tube is extended into the accommodating cavity again, and the capillary tube operating handle is connected with the tube cover.

15. The method of claim 14, wherein said injecting the sample to be tested into the receiving cavity by the blood collection assembly further comprises:

and automatically injecting the sample to be detected collected into the capillary into the accommodating cavity by negative pressure in the tube body.

16. The method of claim 14, wherein said injecting the sample to be tested into the receiving cavity by the blood collection assembly further comprises:

releasing the connection between the capillary cover and the capillary operating handle;

the other end of the capillary tube is connected with a saccule;

and injecting the sample to be detected collected into the capillary into the accommodating cavity by using the negative pressure in the tube body and the pressure provided by the saccule.