CN114533834A - Traditional Chinese medicine composition for preventing and treating cancer - Google Patents
Traditional Chinese medicine composition for preventing and treating cancer Download PDFInfo
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- CN114533834A CN114533834A CN202210334499.4A CN202210334499A CN114533834A CN 114533834 A CN114533834 A CN 114533834A CN 202210334499 A CN202210334499 A CN 202210334499A CN 114533834 A CN114533834 A CN 114533834A
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- A61P35/00—Antineoplastic agents
Abstract
The invention discloses a traditional Chinese medicine composition for preventing and treating cancer, which comprises the following components: monarch drug: 6-25 parts of isatis root, 1-9 parts of trichosanthes kirilowii maxim, 3-15 parts of rhubarb, 6-18 parts of corydalis tuber, 3-6 parts of rhizoma alismatis, 3-9 parts of dried orange peel and 6-18 parts of sculellaria barbata; ministerial drugs: 3-6 parts of peach kernel, 3-6 parts of cortex moutan, 3-12 parts of cortex phellodendri, 6-15 parts of liquorice and 15-21 parts of lalang grass rhizome; adjuvant drugs: 3-6 parts of glauber salt, 3-6 parts of fructus amomi, 3-12 parts of combined spicebush root and 6-18 parts of weeping forsythia capsule; a messenger drug: 3-12 parts of platycodon grandiflorum and 3-9 parts of plantain seed. The traditional Chinese medicine composition disclosed by the invention can remove blood stasis, relieve pain, eliminate distension and fullness and regulate qi through the interaction of monarch, minister, assistant and guide, has a good effect on preventing and treating cancers, and particularly has a good effect on relieving cancer pain.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for preventing and treating cancers and application thereof.
Background
Cancer is a disease that seriously harms human health, and the incidence rate is high. The actual pathogenesis of the disease is not clearly understood at present. The existing cancer treatment is a worldwide problem, and the current treatment methods comprise methods such as surgery, radiotherapy, chemotherapy and the like, which can kill and inhibit the growth of cancer cells, damage normal tissue cells, have the defects of high toxic and side effects and high treatment cost, and often accelerate the metastasis and diffusion of the cancer cells, shorten the survival time of patients and seriously damage the bodies of the patients. The clinical practice is the application of traditional Chinese medicine therapy, but the traditional Chinese medicine therapy only has certain curative effect on partial cancers.
Chinese granted invention CN101491663B discloses a Chinese medicinal composition for treating various cancers, which is prepared from 37 Chinese medicinal herbs including black nightshade seed, guan, airpotato yam, edible tulip, Chinese paris rhizome, dahurian patrinia herb, cantharis, barbed skullcap herb, oldenlandia diffusa, zedoary, glossy privet fruit, dung beetle, trichosanthes fruit and the like through respective impurity removal, drying, mixing and crushing. The health-care tea is prepared by adopting a pure natural medicine formula and a traditional process, and has the functions of regulating the immunologic function of a human body, enhancing the metabolic activity of the human body, killing cancer cells, protecting normal and healthy organism cells and promoting recovery after diseases. Is suitable for clinical treatment of various tumors, especially liver cancer, lung cancer, esophageal cancer, gastric cancer, etc., has the effective rate of 94.7 percent, the cure rate of 86 percent, and has the effects of no metastasis and no relapse.
Chinese granted patent CN1141126C discloses a Chinese medicinal composition for treating cancer, which is prepared from cornu rhinocerotis, calculus bovis, Pseudobulbus cremastrae seu pleiones, radix Isatidis, herba Taraxaci, herba Hedyotidis Diffusae, herba Solani Nigri, fructus forsythiae, squama Manis, Moschus, rhizoma paridis, Bulbus Fritillariae Cirrhosae, radix Paeoniae Rubra, herba Violae, Spica Prunellae, thallus laminariae, radix ferulae, radix Panacis Quinquefolii, radix Angelicae sinensis, radix rehmanniae Preparata, radix Paeoniae alba, radix Salviae Miltiorrhizae, radix Et rhizoma Rhei, herba Artemisiae Scopariae, radix Semiaquilegiae, rhizoma Smilacis Glabrae, and radix et rhizoma Dysosmatis, and optionally vinegar euphorbiae radix and rice-parched Mylabris.
Chinese granted patent CN103623349B discloses a traditional Chinese medicine preparation for treating lung cancer, which is prepared from the following raw material medicines: edible tulip, nux vomica, nidus vespae, cantharis, black nightshade, common burreed rhizome, seaweed, kelp, codonopsis pilosula, astragalus, prepared rhizome of rehmannia, fleece-flower root, largehead atractylodes rhizome, medicated leaven, hawthorn, bitter orange, nutgrass galingale rhizome, turmeric, ground beeltle and other 41 medicines are prepared according to a certain weight ratio. Wherein Pseudobulbus Cremastrae Seu pleiones, Mylabris, semen Strychni, and radix Aconiti Brachypodi by pulverizing and encapsulating, and decocting the rest materials with water.
However, due to the great difficulty in cancer treatment, the inventor Zhao Qianghong (ancestral of the traditional Chinese medicine and Western medicine profession of Chongqing medical university), combined with the traditional Chinese medicine and pharmacology theory in clinical experiments, provides a traditional Chinese medicine composition capable of preventing and treating cancer.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition capable of preventing and treating cancers. In order to achieve the purpose, the invention adopts the following technical scheme:
the invention relates to a traditional Chinese medicine composition for preventing and treating cancer, which comprises the following components:
monarch drug: 6-25 parts of isatis root, 1-9 parts of trichosanthes kirilowii maxim, 3-15 parts of rhubarb, 6-18 parts of corydalis tuber, 3-6 parts of rhizoma alismatis, 3-9 parts of dried orange peel and 6-18 parts of sculellaria barbata;
ministerial drugs: 3-6 parts of peach kernel, 3-6 parts of cortex moutan, 3-12 parts of cortex phellodendri, 6-15 parts of liquorice and 15-21 parts of lalang grass rhizome;
adjuvant drugs: 3-6 parts of glauber salt, 3-6 parts of fructus amomi, 3-12 parts of combined spicebush root and 6-18 parts of weeping forsythia capsule;
a messenger drug: 3-12 parts of platycodon grandiflorum and 3-9 parts of plantain seed.
It should be noted that the technical effects of the invention can be realized only by the comprehensive cooperation of the monarch, minister, assistant and guide medicines. The absence of any one of these drugs can result in a significant change in efficacy. For example, if corydalis tuber is absent in the monarch drug, the pain is difficult to stop; if the monarch drug is lack of radix Isatidis, deficiency and fever will not recede; if fructus forsythiae is not used as adjuvant drug, the cancer toxin is hard to be eliminated.
In a preferred embodiment of the present invention, the Chinese medicinal composition comprises:
monarch drug: 25 parts of isatis root, 9 parts of trichosanthes kirilowii maxim, 15 parts of rhubarb processed with wine, 18 parts of corydalis tuber, 6 parts of rhizoma alismatis, 9 parts of dried orange peel and 18 parts of sculellaria barbata;
ministerial drugs: 6 parts of peach kernel, 6 parts of cortex moutan, 12 parts of cortex phellodendri, 15 parts of liquorice and 21 parts of lalang grass rhizome;
adjuvant drugs: 9 parts of glauber salt, 6 parts of fructus amomi, 12 parts of combined spicebush root and 18 parts of weeping forsythia;
a messenger drug: 12 parts of platycodon grandiflorum and 9 parts of plantain seed.
In a preferred embodiment of the present invention, the Chinese medicinal composition comprises:
monarch drug: 20 parts of isatis root, 6 parts of trichosanthes kirilowii maxim, 10 parts of rhubarb processed with wine, 10 parts of corydalis tuber, 5 parts of rhizoma alismatis, 6 parts of dried orange peel and 15 parts of sculellaria barbata;
ministerial drugs: 4 parts of peach kernel, 4 parts of cortex moutan, 9 parts of cortex phellodendri, 10 parts of liquorice and 15 parts of lalang grass rhizome;
adjuvant drugs: 4 parts of glauber salt, 4 parts of fructus amomi, 9 parts of combined spicebush root and 15 parts of weeping forsythia;
a messenger drug: 9 parts of platycodon grandiflorum and 6 parts of plantain seed.
In a preferred embodiment of the present invention, the Chinese medicinal composition comprises:
monarch drug: 10 parts of isatis root, 3 parts of trichosanthes kirilowii maxim, 6 parts of rhubarb, 6 parts of corydalis tuber, 3 parts of rhizoma alismatis, 3 parts of dried orange peel and 6 parts of sculellaria barbata;
ministerial drugs: 3 parts of peach kernel, 3 parts of cortex moutan, 3 parts of cortex phellodendri, 6 parts of liquorice and 15 parts of lalang grass rhizome;
adjuvant drugs: 3-6 parts of glauber salt, 3-6 parts of fructus amomi, 3-12 parts of combined spicebush root and 6-18 parts of weeping forsythia capsule;
a messenger drug: 3 parts of platycodon grandiflorum and 3 parts of plantain seed.
In a preferred embodiment of the present invention, the Chinese medicinal composition is prepared into an oral preparation, which includes but is not limited to: decoction, powder, tablet, capsule, pill; preferably, the oral formulation is a honey bolus.
The invention also relates to application of the traditional Chinese medicine composition in preparing a medicine for treating cancer prevention.
The invention also relates to application of the traditional Chinese medicine composition in preparing a medicine for treating cancer.
The invention also relates to application of the traditional Chinese medicine composition in preparing a medicine for relieving cancer pain.
Advantageous effects
The traditional Chinese medicine composition disclosed by the invention can remove blood stasis, relieve pain, eliminate distension and fullness and regulate qi through the interaction of monarch, minister, assistant and guide, has a good effect on preventing and treating cancers, and particularly has a good effect on relieving cancer pain.
Detailed Description
The present invention is described in more detail below with reference to the examples of the specification to assist understanding of the invention.
Example 1: prescription composition, dosage and efficacy (generous)
Monarch drug: 25 g of isatis root, 9 g of trichosanthes kirilowii maxim, 15 g of wine-processed rhubarb, 18 g of corydalis tuber, 6 g of alisma orientale, 9 g of dried orange peel and 18 g of sculellaria barbata;
ministerial drugs: 6 g of peach kernel, 6 g of cortex moutan, 12 g of phellodendron, 15 g of liquorice and 21 g of cogongrass rhizome;
adjuvant drugs: 9 g of glauber salt, 6 g of villous amomum fruit, 12 g of combined spicebush root and 18 g of weeping forsythia capsule;
a messenger drug: 12 g of platycodon root and 9 g of plantain seed;
the efficacy is as follows: dispel blood stasis and alleviate pain, relieve stuffiness and pain, regulate qi, stop bleeding and cultivate vigour.
Applicable to patients: is mainly used for the exacerbation period of cancer patients.
Example 1: prescription composition, dosage and efficacy (Chinese prescription)
Monarch drug: 20 g of isatis root, 6 g of trichosanthes kirilowii maxim, 10 g of wine-processed rhubarb, 10 g of corydalis tuber, 5 g of alisma orientale, 6 g of dried orange peel and 15 g of sculellaria barbata;
ministerial drugs: 4 g of peach kernel, 4 g of cortex moutan, 9 g of phellodendron, 10 g of liquorice and 15 g of lalang grass rhizome;
adjuvant drugs: 4 g of glauber salt, 4 g of villous amomum fruit, 9 g of combined spicebush root and 15 g of weeping forsythia capsule;
a messenger drug: 9 g of platycodon root and 6 g of plantain seed;
the efficacy is as follows: dispel blood stasis and alleviate pain, relieve stuffiness and pain, regulate qi, stop bleeding and cultivate vigour.
Applicable to patients: mainly used for the common treatment period of cancer patients.
Example 3: prescription composition, dosage and efficacy (Xiaofang)
Monarch drug: 10 g of isatis root, 3 g of trichosanthes kirilowii maxim, 6 g of wine-processed rhubarb, 6 g of corydalis tuber, 3 g of alisma orientale, 3 g of dried orange peel and 6 g of sculellaria barbata;
ministerial drugs: peach kernel 3 g, root bark of tree peony 3 g, phellodendron bark 3 g, licorice root 6 g, cogongrass rhizome 15 g;
adjuvant drugs: 3-6 g of glauber salt, 3-6 g of villous amomum fruit, 3-12 g of combined spicebush root and 6-18 g of weeping forsythia capsule;
a messenger drug: 3 g of platycodon root and 3 g of plantain seed;
the efficacy is as follows: dispel blood stasis and alleviate pain, relieve stuffiness and pain, regulate qi, stop bleeding and cultivate vigour.
Applicable to patients: mainly used for the consolidation phase of the treatment result of cancer patients
The processing method and the flow are as follows:
selecting the above materials, removing impurities, extracting, processing, making into watered pill, sealing, drying in the shade, and storing.
Example 4: pharmacodynamic experiment
Brief description of partial success of Using the Chinese medicinal formulation
1. Old is male, age 76, mountain area of Chongqing city, cadre; the Chinese medicinal preparation is examined in a trio hospital in 2004, is diagnosed as 'giant lung tumor', still has cancer blocks to live after being treated by taking the Chinese medicinal preparation to 81 years old, the cancer blocks are not expanded continuously, and the life is normal and healthy. (three months of administration period)
2. Vast for the rest of the people, male, 49 years old, Qijiang district people in Chongqing city, teacher; examined in 2008 in a triot of hospitals, diagnosed as "advanced bone marrow cancer" with symptoms of pain and insomnia, no surgery; after the traditional Chinese medicine preparation is taken for treatment, day and night pain disappears, and after 7 years, the symptoms do not relapse, and the life is normal and healthy. (three months of administration period)
3. Luo Zhifu, male, 59 years old, people in Jiulong slope area of Chongqing city, residents in certain area of Chongqing city; the patient is diagnosed with rectal cancer and liver cancer after examination in his hospital in 2017, and is diagnosed with colorectal cancer and liver cancer operation after the examination in the hospital after operation in 2019, and is diagnosed with liver cancer recurrence after the examination in the hospital, and the cancer lump is 53mm, so that the patient can not be treated by operation again; after the treatment by taking the traditional Chinese medicine prescription, the traditional Chinese medicine prescription is still healthy after being taken for three years.
4. The Roxburgh cinnamon, women, 56 years old, people in the Jiulong slope area in Chongqing city, and residents in a certain area in Chongqing city; the patient was examined in his hospital in 2019 and was diagnosed with "liver cancer", and severe hematemesis symptom appeared in 2020; after the traditional Chinese medicine prescription is taken for treatment, hematemesis disappears, hematemesis symptoms do not appear until now, the traditional Chinese medicine prescription is still taken intermittently, the life quality is better, and the traditional Chinese medicine prescription is still healthy.
The foregoing describes preferred embodiments of the present invention, but is not intended to limit the invention thereto. Modifications and variations of the embodiments disclosed herein may be made by those skilled in the art without departing from the scope and spirit of the invention.
Claims (9)
1. A Chinese medicinal composition for preventing and treating cancer comprises:
monarch drug: 6-25 parts of isatis root, 1-9 parts of trichosanthes kirilowii maxim, 3-15 parts of rhubarb, 6-18 parts of corydalis tuber, 3-6 parts of rhizoma alismatis, 3-9 parts of dried orange peel and 6-18 parts of sculellaria barbata;
ministerial drugs: 3-6 parts of peach kernel, 3-6 parts of cortex moutan, 3-12 parts of cortex phellodendri, 6-15 parts of liquorice and 15-21 parts of lalang grass rhizome;
adjuvant drugs: 3-6 parts of glauber salt, 3-6 parts of fructus amomi, 3-12 parts of combined spicebush root and 6-18 parts of weeping forsythia capsule;
a messenger drug: 3-12 parts of platycodon grandiflorum and 3-9 parts of plantain seed.
2. A traditional Chinese medicine composition for preventing and treating cancer comprises:
monarch drug: 25 parts of isatis root, 9 parts of trichosanthes kirilowii maxim, 15 parts of rhubarb processed with wine, 18 parts of corydalis tuber, 6 parts of rhizoma alismatis, 9 parts of dried orange peel and 18 parts of sculellaria barbata;
ministerial drugs: 6 parts of peach kernel, 6 parts of cortex moutan, 12 parts of cortex phellodendri, 15 parts of liquorice and 21 parts of lalang grass rhizome;
adjuvant drugs: 9 parts of glauber salt, 6 parts of fructus amomi, 12 parts of combined spicebush root and 18 parts of weeping forsythia;
a messenger drug: 12 parts of platycodon grandiflorum and 9 parts of plantain seed.
3. A traditional Chinese medicine composition for preventing and treating cancer comprises:
monarch drug: 20 parts of isatis root, 6 parts of trichosanthes kirilowii maxim, 10 parts of rhubarb processed with wine, 10 parts of corydalis tuber, 5 parts of rhizoma alismatis, 6 parts of dried orange peel and 15 parts of sculellaria barbata;
ministerial drugs: 4 parts of peach kernel, 4 parts of cortex moutan, 9 parts of cortex phellodendri, 10 parts of liquorice and 15 parts of lalang grass rhizome;
adjuvant drugs: 4 parts of glauber salt, 4 parts of fructus amomi, 9 parts of combined spicebush root and 15 parts of weeping forsythia;
a messenger drug: 9 parts of platycodon grandiflorum and 6 parts of plantain seed.
4. A traditional Chinese medicine composition for preventing and treating cancer comprises:
monarch drug: 10 parts of isatis root, 3 parts of trichosanthes kirilowii maxim, 6 parts of rhubarb, 6 parts of corydalis tuber, 3 parts of rhizoma alismatis, 3 parts of dried orange peel and 6 parts of sculellaria barbata;
ministerial drugs: 3 parts of peach kernel, 3 parts of cortex moutan, 3 parts of cortex phellodendri, 6 parts of liquorice and 15 parts of lalang grass rhizome;
adjuvant drugs: 3-6 parts of glauber salt, 3-6 parts of fructus amomi, 3-12 parts of combined spicebush root and 6-18 parts of weeping forsythia capsule;
a messenger drug: 3 parts of platycodon grandiflorum and 3 parts of plantain seed.
5. The composition of any one of claims 1-4, wherein the composition is formulated for oral administration.
6. The traditional Chinese medicine composition of claim 5, wherein the oral preparation is a decoction, a powder, a tablet, a capsule or a pill; preferably, the oral formulation is a honey bolus.
7. Use of the Chinese medicinal composition of any one of claims 1-6 in the preparation of a medicament for treating cancer.
8. The use of the Chinese medicinal composition of any one of claims 1-6 in the preparation of a medicament for the treatment of cancer.
9. Use of the Chinese medicinal composition of any one of claims 1-6 in the preparation of a medicament for relieving cancer pain.
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