CN114236129A - In-vitro immunodiagnosis reagent background luminescence processing system - Google Patents
In-vitro immunodiagnosis reagent background luminescence processing system Download PDFInfo
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- CN114236129A CN114236129A CN202111565853.6A CN202111565853A CN114236129A CN 114236129 A CN114236129 A CN 114236129A CN 202111565853 A CN202111565853 A CN 202111565853A CN 114236129 A CN114236129 A CN 114236129A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
Abstract
The invention discloses an in vitro immunodiagnosis reagent background luminescence processing system, which comprises a machine body shell, wherein a working cavity is arranged in the machine body shell, a centrifugal cavity with an upward opening is arranged in the bottom wall of the working cavity, a first rotating block which is rotatably connected is arranged in the centrifugal cavity, a plurality of shaking cavities which are annularly arranged and penetrate through the upper surface and the lower surface of the first rotating block are arranged in the first rotating block, and a clamping block is fixedly arranged in each shaking cavity; the placing block can move in a reciprocating mode under the driving of the first electric push rod, the effect that the object to be detected and the diagnostic reagent are quickly mixed together through quick shaking under the driving of the first electric push rod is achieved, the first rotating block can drive the test tube placed in the test tube placing cavity to rotate under the driving of the second motor, and the effect that the test tube is driven to rotate quickly so that the object to be detected which is not combined with the diagnostic reagent, the object to be detected which is not combined with the diagnostic reagent and the object to be detected which are combined together are layered through centrifugal force is achieved.
Description
Technical Field
The invention relates to the technical field of in-vitro immunodiagnosis, in particular to an in-vitro immunodiagnosis reagent background luminescence processing system.
Background
The in vitro immunodiagnosis detection method is a series of experimental methods for measuring antigen and antibody designed by applying immunological theory, and its main principle is that the antigen or antibody specificity is used to capture the tested substance in specimen, then the antigen or antibody combined with luminescent material in advance is used to mark the captured tested substance so as to indirectly mark the luminescent material on the tested substance, and the luminescent material marked on the tested substance is used to measure its luminescent value by means of instrument, then the concentration of tested substance is calculated by means of fitting curve.
In the prior art, a cleaning solution is generally used for cleaning redundant diagnostic reagents, but most instruments have insufficient cleaning strength to the whole reaction system, so that luminescent substances which are not combined with an object to be detected in the reaction system cannot be eluted, a phenomenon of overhigh background luminescence value exists, and the accuracy of a clinical low-concentration sample measuring value is further influenced.
Disclosure of Invention
The invention aims to provide an in-vitro immunodiagnostic reagent background luminescence processing system which is used for overcoming the defects in the prior art.
The invention relates to an in vitro immunodiagnostic reagent background luminescence processing system, which comprises a machine body shell, wherein a working cavity is arranged in the machine body shell, a centrifugal cavity with an upward opening is arranged in the bottom wall of the working cavity, a first rotating block which is rotatably connected is arranged in the centrifugal cavity, a plurality of shaking cavities which are annularly arranged and penetrate through the upper surface and the lower surface of the first rotating block are arranged in the first rotating block, a clamping block is fixedly arranged in the shaking cavities, a placing block is rotatably arranged on the clamping block, a test tube placing cavity which penetrates through the upper surface and the lower surface of the placing block is arranged in the placing block, a mixing and separating assembly which can mix and separate a diagnostic reagent and a detected object is arranged in the centrifugal cavity, a first motor is arranged behind the centrifugal cavity, a first transmission shaft is arranged on the upper end face of the first motor, a support arm is fixedly arranged on the upper end of the first transmission shaft, three first connecting blocks which are triangularly arranged are arranged below the support arm, the movable detection device is characterized in that a moving assembly for controlling the first connecting block to move is arranged in the supporting arm, a suction assembly capable of sucking a diagnostic reagent is arranged in the first connecting block on the left side, a detection assembly capable of detecting the light emitting condition of a combination of the diagnostic reagent and an object to be detected is arranged in the first connecting block on the right side, a rotating cavity with an upward opening is arranged in the bottom wall of the working cavity behind the first motor, a second rotating block is rotatably arranged in the rotating cavity, an auxiliary assembly capable of assisting detection to be smoother is arranged in the rotating cavity, a first fixing block is arranged above the working cavity, a cleaning assembly capable of cleaning a light emitting substance which is not combined with the object to be detected in a reaction system is arranged in the first fixing block, and a protective door penetrating through the surface of the machine body shell is rotatably arranged in front of the first fixing block.
Like this, the support arm that is equipped with just can rotate under the drive of first motor, plays the effect that drives each part removal that sets up on the support arm, can quick drive each detection part quick travel, and the guard gate that is equipped with can keep apart the working chamber with the external world, can effectually prevent that first rotation piece from touching by mistake and leading to the injury when high-speed rotatory detection personnel, also can prevent simultaneously that the too much entering of debris in the air from waiting to detect liquid pollution and waiting to detect liquid.
According to a further technical scheme, the mixing assembly comprises a second motor installed in the bottom wall of the centrifugal cavity, a second transmission shaft is installed on the upper end face of the second motor and fixedly connected with the first rotating block, a first electric push rod corresponding to the position of the placing block is arranged on the second transmission shaft in a rotating mode, and the output end of the first electric push rod is connected with the placing block in a rotating mode.
Therefore, the placing block can reciprocate under the driving of the first electric push rod, the effect of quickly shaking under the driving of the first electric push rod to quickly mix the object to be tested and the diagnostic reagent is realized, the first rotating block can drive the test tube placed in the test tube placing cavity to rotate under the driving of the second motor, the effect of driving the test tube to quickly rotate and layering the object not combined with the diagnostic reagent and the object to be tested combined with the combined object to be tested by utilizing centrifugal force is realized, the combined object to be tested of the combined diagnostic reagent is precipitated at the bottom of the test tube due to larger mass, the problem that the background light is too strong and the detection result is seriously influenced due to too much sucked the uncombined diagnostic reagent can be effectively solved, and meanwhile, the first electric push rod can drive the test tube to incline towards the side far away from the second transmission shaft during centrifugation, can prevent the mixed liquid from pouring out.
According to the technical scheme, the moving assembly comprises a third motor arranged in the lower surface of the support arm, a third transmission shaft is arranged on the lower end face of the third motor, a second connecting block is fixedly arranged at the lower end of the third transmission shaft, three second electric push rods corresponding to the first connecting block in position are arranged in the second connecting block, and the output end of each second electric push rod is fixedly connected with the upper surface of the first connecting block.
Therefore, the first connecting block can be driven by the third motor and the second electric push rod to change positions, and the effect of changing stations to finish different detection actions is achieved.
Further technical scheme, the absorption subassembly is including setting up in the left the chamber of keeping in the first connecting block, it is equipped with to run through the left chamber diapire of keeping in the reagent straw of the lower surface of first connecting block, install first water pump on the reagent straw.
Like this, the first water pump that is equipped with just can control diagnostic reagent and get into the intracavity of keeping in or discharge the intracavity of keeping in, plays and absorbs diagnostic reagent and toward waiting to wait to examine the effect that adds diagnostic reagent in the test tube, and automatic control addition can effectual solution manual work add the inaccurate problem of measurement, reduces measurement personnel's intensity of labour.
According to the technical scheme, the detection assembly comprises a detection cavity arranged on the right side in the first connecting block, a diagnostic reagent luminescence detector is installed in the top wall of the detection cavity, a detection suction pipe penetrating through the lower surface of the first connecting block on the right side is arranged on the bottom wall of the detection cavity, and a second water pump is installed on the detection suction pipe.
Thus, the provided diagnostic reagent luminescence detector can detect the luminescence condition of the diagnostic reagent analyte conjugate sucked into the detection cavity by the second water pump, and then the diagnosis result is judged by analyzing the luminescence spectrum.
According to the technical scheme, the auxiliary assembly comprises a fourth motor installed in the bottom wall of the rotary cavity, a fourth transmission shaft is installed on the upper end face of the fourth motor and fixedly connected with a second rotating block, a cleaning cavity with an upward opening is formed in the second rotating block, an ultrasonic generator is installed in the bottom wall of the cleaning cavity, a plurality of diagnostic reagent cavities which are annularly arranged are formed in the rear of the cleaning cavity, and a protective cover which is rotatably connected is installed at the rear of the rotary cavity.
Therefore, the second rotating block can rotate under the driving of the fourth motor, the effect of replacing the position of the diagnostic reagent cavity according to requirements so as to facilitate the reagent suction pipe to absorb different diagnostic reagents is achieved, the ultrasonic generator can generate ultrasonic waves to be matched with decontamination liquid in the cleaning cavity to remove residual pollutants on the surfaces of objects, the effect of preventing the objects to be detected from being cross-polluted is achieved, the protective cover can be used for closing and cutting off the connection between the diagnostic reagent cavity and the outside when the system stops running, and the external pollutants are prevented from entering the diagnostic reagent cavity to pollute the diagnostic reagent.
A further technical scheme, wash the subassembly including set up in the first fixed block just around position symmetry and the ascending draw-in groove of opening, it is equipped with the washing liquid bottle to slide in the draw-in groove, be equipped with washing liquid storage chamber in the washing liquid bottle, washing liquid storage chamber diapire is equipped with and runs through the water pipe of first fixed block lower surface, install the third water pump on the water pipe, middle be equipped with in the first connecting block and run through in the middle the washing liquid recovery straw of first connecting block lower surface, washing liquid recovery straw rear is equipped with and runs through in the middle the washing liquid injection straw of first connecting block lower surface, the place ahead the water pipe with washing liquid recovery straw is connected, the rear the water pipe with washing liquid injection straw is connected.
Therefore, the third water pumps are matched with each other, so that the clean cleaning liquid in the rear cleaning liquid storage cavity can be injected into the mixed solution in the tube to be tested, the redundant unnecessary waste liquid is sucked into the front cleaning liquid storage cavity, the effect of washing the unnecessary substances in the mixed liquid in the tube by using the special cleaning liquid is achieved, and the situation that the detection result is influenced due to the fact that the detection background is excessively high in luminance when the diagnostic reagent which is not combined with the object to be tested is detected is prevented.
The invention has the beneficial effects that:
firstly, the placing block provided by the invention can reciprocate under the driving of the first electric push rod, so as to play a role of quickly shaking under the driving of the first electric push rod to quickly mix the object to be detected and the diagnostic reagent together, the first rotating block can drive the test tube placed in the test tube placing cavity to rotate under the driving of the second motor, so that the test tube is driven to rotate rapidly to layer the uncombined diagnostic reagent, the uncombined object to be detected and the combined object of the combined diagnostic reagent and the object to be detected by utilizing centrifugal force, the combined object of the combined diagnostic reagent and the object to be detected is precipitated at the bottom of the test tube due to higher mass, the problem that the background light is too strong because the uncombined diagnostic reagent is sucked too much can be effectively solved, lead to the fact serious influence to the testing result, first electric putter can drive the test tube towards keeping away from second transmission shaft one side slope simultaneously when the centrifugation, can prevent that mixed liquid from empting out.
The second, the first water pump that this invention was equipped with can control diagnostic reagent and get into the intracavity of keeping in or discharge the intracavity of keeping in, play and absorb diagnostic reagent and toward waiting to examine the effect that adds diagnostic reagent in the test tube, the automatic control addition can effectual solution manual work add the inaccurate problem of measurement and fall, low measurement personnel's intensity of labour.
And the second rotating block can rotate under the drive of the fourth motor, so that the position of the diagnostic reagent cavity can be changed as required, a reagent suction tube can conveniently suck different diagnostic reagents, the ultrasonic generator can generate ultrasonic waves to be matched with decontamination liquid in the cleaning cavity to remove residual pollutants on the surfaces of objects, the function of preventing the cross contamination of the objects to be detected is achieved, the protective cover can close and cut off the connection between the diagnostic reagent cavity and the outside when the system stops running, and the external pollutants are prevented from entering the diagnostic reagent cavity to pollute the diagnostic reagent.
Drawings
FIG. 1 is a schematic diagram of an external appearance of a background luminescence processing system for an in vitro immunodiagnostic reagent according to the present invention;
FIG. 2 is a schematic view of the structure of FIG. 1 taken at A-A in accordance with the present invention;
FIG. 3 is a schematic diagram of the structure of the mobile assembly of FIG. 2 according to the present invention;
FIG. 4 is a schematic view of the structure of FIG. 2 at B-B in accordance with the present invention;
FIG. 5 is a schematic diagram of the mixing assembly of FIG. 4 according to the present invention;
FIG. 6 is a schematic diagram of the detection assembly of FIG. 4 according to the present invention;
in the figure:
11. a body housing; 12. a centrifugal chamber; 13. a second motor; 14. a second drive shaft; 15. a first rotating block; 16. placing the blocks; 17. a first drive shaft; 18. a working chamber; 19. a support arm; 20. a water pipe; 21. a first fixed block; 22. shaking the cavity; 23. a clamping block; 24. a first motor; 25. a first electric push rod; 26. a reagent pipette; 27. a first connection block; 28. a second connecting block; 29. a third drive shaft; 30. detecting the straw; 31. cleaning solution bottles; 32. a rotating chamber; 33. a fourth motor; 34. a fourth drive shaft; 35. injecting the cleaning solution into the suction pipe; 36. a suction pipe for recovering the cleaning liquid; 37. a second water pump; 38. a diagnostic reagent luminescence detector; 39. a protective cover; 40. a diagnostic reagent chamber; 41. a second turning block; 42. a cleaning chamber; 43. an ultrasonic generator; 44. a card slot; 45. a cleaning liquid storage chamber; 46. a temporary storage cavity; 47. a third water pump; 48. a protective door; 49. a test tube placement chamber; 50. a third motor; 51. a second electric push rod; 52. a detection chamber; 53. a first water pump; 54. a mixing and separating assembly; 55. a moving assembly; 56. a suction assembly; 57. a detection component; 58. an auxiliary component; 59. and cleaning the assembly.
Detailed Description
For purposes of making the objects and advantages of the present invention more apparent, the following detailed description of the present invention will be taken in conjunction with the examples, it being understood that the following text is intended to describe only one in vitro immunodiagnostic reagent background luminescence treatment system or several specific embodiments of the present invention, and is not intended to strictly limit the scope of the invention as specifically claimed, and as used herein, the terms up, down, left and right are not limited to their strict geometric definitions, but include tolerances for reasonable and inconsistent machining or human error, the following detailed description of specific features of the in vitro immunodiagnostic reagent background luminescence treatment system:
referring to fig. 1 to 6, an in vitro immunodiagnostic reagent background light-emitting processing system according to an embodiment of the present invention includes a machine body housing 11, a working chamber 18 is disposed in the machine body housing 11, a centrifugal chamber 12 with an upward opening is disposed in a bottom wall of the working chamber 18, a first rotating block 15 rotatably connected to the centrifugal chamber 12 is disposed in the centrifugal chamber 12, a plurality of shaking chambers 22 annularly arranged and penetrating through upper and lower surfaces of the first rotating block 15 are disposed in the first rotating block 15, a clamping block 23 is fixedly disposed in the shaking chambers 22, a placing block 16 is rotatably disposed on the clamping block 23, test tube placing chambers 49 penetrating through upper and lower surfaces of the placing block 16 are disposed in the placing block 16, a mixing assembly 54 capable of mixing and separating a diagnostic reagent and a detected object is disposed in the centrifugal chamber 12, a first motor 24 is disposed behind the centrifugal chamber 12, a first transmission shaft 17 is disposed on an upper end surface of the first motor 24, a support arm 19 is fixedly arranged at the upper end of the first transmission shaft 17, three first connecting blocks 27 which are arranged in a triangular manner are arranged below the support arm 19, a moving component 55 for controlling the movement of the first connecting blocks 27 is arranged in the support arm 19, a suction component 56 capable of sucking a diagnostic reagent is arranged in the first connecting block 27 on the left side, a detection component 57 capable of detecting the light emitting condition of a combination of the diagnostic reagent and an object to be detected is arranged in the first connecting block 27 on the right side, a rotating cavity 32 with an upward opening is arranged in the bottom wall of the working cavity 18 behind the first motor 24, a second rotating block 41 is rotationally arranged in the rotating cavity 32, an auxiliary component 58 capable of assisting in detecting more smoothly is arranged in the rotating cavity 32, a first fixing block 21 is arranged above the working cavity 18, and a cleaning component 59 capable of cleaning luminescent substances which are not combined with the object to be detected in a reaction system is arranged in the first fixing block 21, a protective door 48 penetrating the surface of the machine body shell 11 is rotatably arranged in front of the first fixed block 21.
Advantageously or exemplarily, the mixing-separating assembly 54 includes a second motor 13 installed in the bottom wall of the centrifugal cavity 12, a second transmission shaft 14 is installed on an upper end surface of the second motor 13, the second transmission shaft 14 is fixedly connected with the first rotating block 15, a first electric push rod 25 corresponding to the position of the placing block 16 is rotatably installed on the second transmission shaft 14, an output end of the first electric push rod 25 is rotatably connected with the placing block 16, when the second motor 13 is started, the second motor 13 drives the first rotating block 15 to rotate through the second transmission shaft 14, and when the first electric push rod 25 moves, the placing block 16 can be driven to move.
Beneficially or exemplarily, the moving assembly 55 includes a third motor 50 installed in the lower surface of the support arm 19, a third transmission shaft 29 is installed on the lower end surface of the third motor 50, a second connection block 28 is fixedly installed on the lower end of the third transmission shaft 29, three second electric push rods 51 corresponding to the first connection block 27 are installed in the second connection block 28, an output end of each second electric push rod 51 is fixedly connected to the upper surface of the first connection block 27, when the third motor 50 is started, the third motor 50 drives the second connection block 28 to rotate through the third transmission shaft 29, and when the second electric push rods 51 are started, the second electric push rods 51 drive the first connection block 27 to move.
Advantageously or exemplarily, the sucking assembly 56 comprises a temporary storage chamber 46 disposed in the first connecting block 27 on the left side, the reagent suction pipe 26 penetrating through the lower surface of the first connecting block 27 on the left side is disposed on the bottom wall of the temporary storage chamber 46, and the first water pump 53 is mounted on the reagent suction pipe 26 and can control the diagnostic reagent to enter the temporary storage chamber 46 or to be discharged out of the temporary storage chamber 46 when the first water pump 53 is activated.
Advantageously or exemplarily, the detection assembly 57 includes a detection chamber 52 disposed in the right first connecting block 27, a diagnostic reagent luminescence detector 38 is installed in the top wall of the detection chamber 52, a detection suction pipe 30 penetrating through the lower surface of the right first connecting block 27 is disposed on the bottom wall of the detection chamber 52, a second water pump 37 is installed on the detection suction pipe 30, when the second water pump 37 is activated, the diagnostic reagent analyte conjugate can be sucked into the detection chamber 52 for detection, and when the diagnostic reagent luminescence detector 38 is activated, the luminescence of the diagnostic reagent analyte conjugate in the advance solution can be detected.
Advantageously or exemplarily, said auxiliary assembly 58 comprises a fourth motor 33 mounted in the bottom wall of said rotating chamber 32, a fourth transmission shaft 34 is installed on the upper end surface of the fourth motor 33, the fourth transmission shaft 34 is fixedly connected with the second rotating block 41, a cleaning cavity 42 with an upward opening is arranged in the second rotating block 41, an ultrasonic generator 43 is arranged in the bottom wall of the cleaning cavity 42, a plurality of diagnostic reagent chambers 40 which are annularly arranged are arranged behind the cleaning chamber 42, a protective cover 39 which is rotatably connected is arranged behind the rotary chamber 32, when the fourth motor 33 is started, the fourth motor 33 drives the second rotating block 41 to rotate through the fourth transmission shaft 34, the ultrasonic generator 43 can generate ultrasonic waves to cooperate with decontamination liquid in the cleaning cavity 42 to remove residual pollutants on the surfaces of various objects when being started, and the protective cover 39 can be automatically opened and closed when being started.
Advantageously or exemplarily, the cleaning assembly 59 includes a clamping groove 44 disposed in the first fixing block 21 and symmetrically disposed in front and back directions and having an upward opening, a cleaning solution bottle 31 is slidably disposed in the clamping groove 44, a cleaning solution storage chamber 45 is disposed in the cleaning solution bottle 31, a water pipe 20 penetrating through the lower surface of the first fixing block 21 is disposed at the bottom wall of the cleaning solution storage chamber 45, a third water pump 47 is mounted on the water pipe 20, a cleaning solution recovery suction pipe 36 penetrating through the lower surface of the first connecting block 27 is disposed in the middle of the first connecting block 27, a cleaning solution injection suction pipe 35 penetrating through the lower surface of the first connecting block 27 is disposed behind the cleaning solution recovery suction pipe 36, the front water pipe 20 is connected to the cleaning solution recovery suction pipe 36, the rear water pipe 20 is connected to the cleaning solution injection suction pipe 35, when the rear third water pump 47 is activated, the cleaning liquid in the rear cleaning liquid storage chamber 45 can be injected into the pipe to be tested, and when the third water pump 47 in front is started, the redundant cleaning liquid in the pipe to be tested can be sucked into the cleaning liquid storage chamber 45 in front.
The invention relates to an in vitro immunodiagnosis reagent background luminescence processing system, which comprises the following working procedures:
when the test is needed, the protective door 48 is opened, the test tube containing the object to be tested is placed in the test tube placing cavity 49, the fourth motor 33 is started to drive the diagnostic reagent cavity 40 containing the needed diagnostic reagent to rotate to the liquid taking level, the first motor 24, the third motor 50, the left second electric push rod 51 and the first water pump 53 are started to drive the reagent suction tube 26 to move, the diagnostic reagent in the diagnostic reagent cavity 40 is injected into the test tube, the first electric push rod 25 is started to drive the test tube to quickly shake so that the object to be tested and the diagnostic reagent are quickly mixed together, the actions are repeated to inject the diagnostic reagent into all the test tubes, the first motor 24, the third motor 50, the left second electric push rod 51 and the first water pump 53 are started to drive the cleaning liquid recovery suction tube 36 and the cleaning liquid injection suction tube 35 to move and be inserted into the test tubes, and the third water pump 47 is started to cooperate with each other to inject the clean cleaning liquid in the rear cleaning liquid storage cavity 45 into the test tube to be tested The mixed solution in the test tube is sucked into the cleaning solution storage cavity 45 in front, unnecessary waste liquid is washed away by special cleaning solution, all the test tubes are cleaned by the cleaning solution by repeating the actions, then the first electric push rod 25 is started to drive the test tubes to incline towards one side far away from the second transmission shaft 14 during centrifugation, the mixed solution can be prevented from being poured out, then the first rotating block 15 is started to drive the test tubes placed in the test tube placing cavity 49 to rotate, and the unbound diagnostic reagent, the unbound object and the bound diagnostic reagent object combination are layered by centrifugal force, so that the bound diagnostic reagent object combination is deposited at the bottom of the test tubes due to larger mass, the problem that the unbound diagnostic reagent is sucked too much to cause over-strong background luminescence and cause serious influence on the detection result can be effectively solved, then the first motor 24, the third motor 50, the second electric push rod 51 and the first water pump 53 are started to drive the detection suction pipe 30 to move and insert into the bottom of the test tube, then the second water pump 37 sucks the processed tested object into the detection cavity 52, then the diagnostic reagent luminescence detector 38 is started to detect the luminescence degree of the tested object in the detection cavity 52, then the actions are repeated, meanwhile, the reagent suction pipe 26, the detection suction pipe 30, the cleaning liquid injection suction pipe 35 and the cleaning liquid recovery suction pipe 36 need to move into the cleaning cavity 42 after being inserted into the test tube every time, then the ultrasonic generator 43 is started to generate ultrasonic waves to cooperate with the decontamination liquid in the cleaning cavity 42 to remove the residual pollutants on the surface of each object so as to prevent the cross contamination of the tested object, and all actions are completed.
It will be apparent to those skilled in the art that various modifications may be made to the above embodiments without departing from the general spirit and concept of the invention. All falling within the scope of protection of the present invention. The protection scheme of the invention is subject to the appended claims.
Claims (8)
1. An in vitro immunodiagnostic reagent background luminescence processing system comprises a machine body shell (11), and is characterized in that: the test tube placing device is characterized in that a working cavity (18) is arranged in the machine body shell (11), a centrifugal cavity (12) with an upward opening is arranged in the bottom wall of the working cavity (18), a first rotating block (15) connected in a rotating mode is arranged in the centrifugal cavity (12), a plurality of shaking cavities (22) which are arranged in an annular mode and penetrate through the upper surface and the lower surface of the first rotating block (15) are arranged in the first rotating block (15), clamping blocks (23) are fixedly arranged in the shaking cavities (22), placing blocks (16) are arranged on the clamping blocks (23) in a rotating mode, test tube placing cavities (49) which penetrate through the upper surface and the lower surface of the placing blocks (16) are arranged in the placing blocks (16), a mixing and separating assembly (54) capable of mixing and separating a diagnostic reagent and a detected object is arranged in the centrifugal cavity (12), a first motor (24) is installed on the rear side of the centrifugal cavity (12), and a first transmission shaft (17) is installed on the upper end face of the first motor (24), the upper end of the first transmission shaft (17) is fixedly provided with a support arm (19), three first connecting blocks (27) which are arranged in a triangular mode are arranged below the support arm (19), and a moving assembly (55) for controlling the first connecting blocks (27) to move is arranged in the support arm (19).
2. The in vitro immunodiagnostic reagent background luminescence processing system of claim 1, wherein: a suction component (56) capable of sucking the diagnostic reagent is arranged in the first connecting block (27) on the left side, a detection component (57) capable of detecting the luminescence condition of a combination of the diagnostic reagent and the object to be detected is arranged in the first connecting block (27) on the right side, a rotary cavity (32) with an upward opening is arranged in the bottom wall of the working cavity (18) behind the first motor (24), a second rotating block (41) is rotationally arranged in the rotating cavity (32), an auxiliary component (58) which can assist in detection to be smoother is arranged in the rotating cavity (32), a first fixed block (21) is arranged above the working cavity (18), a cleaning component (59) capable of washing away luminescent substances which are not combined with the object to be detected in the reaction system is arranged in the first fixed block (21), a protective door (48) penetrating through the surface of the machine body shell (11) is rotatably arranged in front of the first fixed block (21).
3. The in vitro immunodiagnostic reagent background luminescence processing system of claim 2, wherein: mix from subassembly (54) including install in second motor (13) in centrifugal cavity (12) diapire, second transmission shaft (14) are installed to second motor (13) up end, second transmission shaft (14) with first rotation piece (15) fixed connection, rotate on second transmission shaft (14) be equipped with place first electric putter (25) that piece (16) position corresponds, first electric putter (25) output with place piece (16) and rotate and connect.
4. The in vitro immunodiagnostic reagent background luminescence processing system of claim 2, wherein: remove subassembly (55) including install in third motor (50) in support arm (19) lower surface, third transmission shaft (29) are installed to third motor (50) lower terminal surface, third transmission shaft (29) lower extreme has set firmly second connecting block (28), be equipped with in second connecting block (28) three with second electric putter (51) that first connecting block (27) position corresponds, second electric putter (51) output with fixed surface connects on first connecting block (27).
5. The in vitro immunodiagnostic reagent background luminescence processing system of claim 2, wherein: inhale subassembly (56) including setting up in the left chamber (46) of keeping in first connecting block (27), chamber (46) diapire of keeping in is equipped with and runs through the left reagent straw (26) of the lower surface of first connecting block (27), install first water pump (53) on reagent straw (26).
6. The in vitro immunodiagnostic reagent background luminescence processing system of claim 2, wherein: the detection assembly (57) is including setting up in the right side detection chamber (52) in first connecting block (27), install diagnostic reagent luminescence detector (38) in detection chamber (52) roof, detection chamber (52) diapire is equipped with and runs through detection straw (30) of the first connecting block (27) lower surface in right side, install second water pump (37) on detection straw (30).
7. The in vitro immunodiagnostic reagent background luminescence processing system of claim 2, wherein: auxiliary assembly (58) including install in fourth motor (33) in rotatory chamber (32) diapire, fourth transmission shaft (34) are installed to fourth motor (33) up end, fourth transmission shaft (34) with second turning block (41) fixed connection, be equipped with ascending washing chamber (42) of opening in second turning block (41), install supersonic generator (43) in washing chamber (42) diapire, washing chamber (42) rear is equipped with diagnostic reagent chamber (40) that a plurality of rings were arranged, rotatory chamber (32) rear is installed and is rotated visor (39) of connection.
8. The in vitro immunodiagnostic reagent background luminescence processing system of claim 2, wherein: the cleaning assembly (59) comprises a clamping groove (44) which is arranged in the first fixing block (21) and is symmetrical in front and back position and provided with an upward opening, a cleaning liquid bottle (31) is arranged in the clamping groove (44) in a sliding manner, a cleaning liquid storage cavity (45) is arranged in the cleaning liquid bottle (31), a water pipe (20) penetrating through the lower surface of the first fixing block (21) is arranged on the bottom wall of the cleaning liquid storage cavity (45), a third water pump (47) is arranged on the water pipe (20), a cleaning liquid recovery suction pipe (36) penetrating through the middle lower surface of the first connecting block (27) is arranged in the middle of the first connecting block (27), a cleaning liquid injection suction pipe (35) penetrating through the middle lower surface of the first connecting block (27) is arranged behind the cleaning liquid recovery suction pipe (36), and the water pipe (20) in front is connected with the cleaning liquid recovery suction pipe (36), the rear water pipe (20) is connected with the cleaning liquid injection suction pipe (35).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111565853.6A CN114236129B (en) | 2021-12-20 | 2021-12-20 | In-vitro immunodiagnosis reagent background luminescence processing system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111565853.6A CN114236129B (en) | 2021-12-20 | 2021-12-20 | In-vitro immunodiagnosis reagent background luminescence processing system |
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