CN114199654A - Pathological slide sequential dyeing, washing and air-drying device and method - Google Patents

Abstract

The invention relates to a pathological slide sequential staining, washing and air-drying device and a method, wherein the device comprises: a moving mechanism for moving the slide; a liquid pumping mechanism for spraying liquid onto the slide; a case for storing liquid and air-drying the slide; the motion mechanism comprises a loading platform, a translation component for driving the loading platform to translate and a rotating component for driving the loading platform to rotate; the liquid pumping mechanism comprises a spraying head, a plurality of sets of liquid pumping components for driving the spraying head to spray and an adjusting component for controlling the opening and closing of each liquid pumping component; the box body is provided with a plurality of liquid storage tanks, different dye liquor or clean water is filled in each liquid storage tank, and each liquid storage tank is correspondingly connected with a set of pump liquid components; the movement mechanism and the liquid pumping mechanism are arranged on the box body, and an air drying assembly is arranged on the box body. Compared with the prior art, the invention can be used for rapid staining treatment and evaluation of cytopathology after fine needle puncture under the guidance of the ultrasonic endoscope for pancreatic lesion and under similar application scenes.

Description

Pathological slide sequential dyeing, washing and air-drying device and method

Technical Field

The invention relates to the technical field of medical devices, in particular to a pathological slide sequential staining, washing and air-drying device and method.

Background

The cell pathology dyeing after the thin needle puncture is handled and is evaluateed and mainly relies on artifical manual dyeing to handle under the ultrasonic endoscope guide of pancreas pathological change is carried out to present hospital, and the processing step can unify the simplification basically to: and washing the slide with the dye solution A for dyeing, washing the slide with the dye solution B for dyeing, washing the slide with clear water for removing floating color, and analyzing after drying. The whole manual operation process is complicated, only one slide can be processed at a time, the efficiency is low, and the biopsy pathological slide needs to be processed and analyzed in time.

The existing automatic glass slide dyeing device can basically treat a plurality of glass slides at the same time, and most dyeing devices adopt a dip dyeing treatment mode, so that the problem that a dye solution is polluted to influence a detection result exists, and the pancreatic pathological glass slides cannot be sequentially dyed and washed in a targeted manner. How to carry out batch automatic rapid staining treatment on cytopathology slides under pancreas puncture and similar application scenes is a technical problem to be solved urgently.

Disclosure of Invention

The invention aims to provide a pathological slide sequential staining, flushing and air-drying device and method, which can be used for rapid staining treatment and evaluation of cytopathology after fine needle puncture under guidance of an ultrasonic endoscope for pancreatic lesion and under similar application scenes.

The purpose of the invention can be realized by the following technical scheme: a pathological slide sequential staining, washing and air-drying device comprises:

a moving mechanism for moving the slide;

a liquid pumping mechanism for spraying liquid onto the slide;

a case for storing liquid and air-drying the slide;

the motion mechanism comprises a loading platform, a translation component for driving the loading platform to translate and a rotating component for driving the loading platform to rotate;

the liquid pumping mechanism comprises a spraying head, a plurality of sets of liquid pumping components for driving the spraying head to spray and an adjusting component for controlling the opening and closing of each liquid pumping component;

the box body is provided with a plurality of liquid storage tanks, different dye liquor or clean water is filled in each liquid storage tank, and each liquid storage tank is correspondingly connected with a set of pump liquid components;

the movement mechanism and the liquid pumping mechanism are arranged on the box body, and an air drying assembly is arranged on the box body. The air drying component is used for air drying after the slide is dyed.

The motion mechanism can respectively realize the translation and the rotation inclination of the pathological slide loading platform and assist the matching dyeing. The box body can be used for fixedly assembling the mechanism to form a relatively closed space.

Preferably, the translation assembly comprises a rack, a translation gear and a first motor;

the rack is arranged on the lower surface of the loading platform, the translation gear is meshed with the rack, and the translation gear is connected with the first motor. The translation assembly is realized by utilizing the meshing of a gear and a rack driven by a motor to convert rotation into translation, and when the translation gear rotates, the rotation is converted into displacement through the meshing of the gear and the rack, so that the loading platform can translate in the horizontal direction.

Preferably, the rotating assembly comprises an inclined large gear, an inclined small gear and a second motor, the inclined large gear is matched with a sliding rail on the lower surface of the loading platform, the inclined large gear is meshed with the inclined small gear, and the inclined small gear is connected with the second motor. The rotation of the rotating component drives the inclined large gear to rotate by the engagement of the inclined small gear, so as to drive the loading platform matched with the inclined large gear to rotate.

Further preferably, the top of the inclined bull gear is of a flush structure and is clamped on the inner side of the slide rail. The lower part of the inclined bull gear is meshed with the inclined pinion gear. Preferably, the inclined bull gear is a half gear with a convex key on the upper surface.

Preferably, the pump liquid subassembly include pump liquid chamber, pump liquid stopper, input tube, output tube and merging tube, pump liquid chamber pass through the input tube and connect the liquid storage tank, pump liquid chamber passes through output tube connection merging tube, the sprinkler head sets up on merging tube, pump liquid stopper set up in pump liquid chamber and connect the adjusting part.

Further preferably, check valves for preventing liquid from flowing backwards are arranged between the liquid storage tank and the input pipe and between the output pipe and the merging pipe.

Preferably, the adjusting assembly drives the pump liquid plugs in different pump liquid cavities to move up and down through multi-stage gear transmission so as to pump different liquids.

Preferably, the adjusting assembly comprises a driving gear, a transmission shaft, a nth gear, an output gear, a transmission rod and a third motor;

the driving gear is meshed with the transmission gear and is connected with a third motor, the transmission gear is fixedly connected to a transmission shaft, three nth gears with mutually staggered tooth parts are fixed on the transmission shaft, the tooth part of each nth gear is meshed with one output gear, and each output gear is connected with a set of pump liquid assembly through a transmission rod; and n is an integer of more than 2. According to different kinds and quantities of dyeing flushing liquid used in the dyeing process under the application condition, a group of components in the liquid pumping mechanism of the device, namely the liquid storage tank, the liquid pumping cavity and the corresponding gear, and the quantity of the transmission rods are correspondingly adjusted. For example, when n total liquids need to be dyed and washed sequentially in the dyeing process, n groups of corresponding parts should be arranged in the liquid pumping mechanism, and a one-nth gear should be adopted as the gear for meshing and controlling the output gears in each group. Preferably, only one third part of the nth gear of the liquid pumping mechanism is provided with gear teeth, and the one third gear drives the output gear only when the transmission gear is meshed with the gear teeth part, so that the transmission rod is driven to drive the liquid pumping plug to suck and pump the dye liquid.

Preferably, the output gear is eccentrically connected with a transmission rod.

Preferably, the upper surface of the loading platform is provided with a slide groove, a slope and a liquid discharge hole;

the slide groove is provided with a clamp at two sides, the slide groove is arranged on a slope, and the liquid discharge hole is arranged on the side wall of the loading platform and is positioned at the lower side of the slope.

Preferably, the liquid pumping mechanism comprises five duckbill spray heads;

the box on be equipped with three stock solution pond, three stock solution pond in store gradually dye liquor A, dye liquor B and clear water.

In the present invention, the spray head having a duckbill shape may make the liquid in a water curtain shape when spraying.

Preferably, the box still include hollow box shell, the motion sets up in the box shell, the air-dry subassembly including set up the fan in the box shell, the ventilation hole has been seted up to the one side relative with the fan on the box shell.

A pathological slide sequential staining, washing and air-drying method is carried out by using the pathological slide sequential staining, washing and air-drying device, and comprises the following steps:

s1: loading a slide to be tested on a loading table, and translating the loading table to the position below a sprinkler head by using a translation assembly;

s2: controlling the first set of pump liquid components to start by using the adjusting component, spraying the dye liquid in the first liquid storage tank from the spraying head, and simultaneously utilizing the translation component to make the loading platform perform reciprocating translation under the spraying head;

s3: controlling the next set of pump liquid components to start by using the adjusting component, spraying the dye liquid in the next liquid storage tank from the spraying head, and simultaneously, utilizing the translation component to make the loading platform perform reciprocating translation under the spraying head;

s4: repeating the step S3 until clear water needs to be pumped;

s5: the loading table is inclined by using the rotating assembly, the pump liquid assembly connected with the liquid storage tank for storing clear water is started by using the adjusting assembly, the clear water is sprayed out of the spraying head, and the loading table is translated back and forth under the condition of inclination by using the translation assembly;

s6: the loading platform is restored to the horizontal by the rotating assembly, and the glass slide is air-dried by the air-drying assembly.

The invention comprises a liquid pumping mechanism which drives a liquid pumping plug in a liquid pumping cavity to move up and down through multi-stage gear transmission to pump out different liquids, a moving mechanism which can respectively realize translation and rotation, and a fan or a similar air drying device which is used for air drying after dyeing.

The invention provides a pathological slide sequential dyeing, flushing and air-drying device and method based on the problems that in the prior art, multiple staining solutions of slides are not easy to dye, and no special staining treatment device is used for rapid staining treatment evaluation of cytopathology after fine needle puncture under guidance of a pancreatic lesion ultrasonic endoscope and similar application scenes.

Compared with the prior art, the invention has the following advantages:

1. the device integrates three processes of dyeing with multiple dye solutions, washing after dyeing and air drying of common glass slides in hospitals, and realizes function integration;

2. the design of the liquid pumping mechanism avoids the problem of using multiple pumps and multiple driving motors, reduces the volume of the device, better meets the characteristic of small space of the existing operating room, and realizes the simplification of the structure;

3. the glass slide dyeing device has the advantages that the dyeing effect is better, the dyeing time is shortened, the loading platform can move horizontally when the dye liquid is sprayed through the translational design of the motion mechanism, the glass slide is dyed more uniformly, the dye liquid on the glass slide is further distributed uniformly through rotation after dyeing, meanwhile, the redundant dye liquid flows down, and the air drying time is shortened;

4. the device has an integrated structure, can shorten the dyeing time of the biopsy sample after puncture for a doctor, is convenient to operate and accords with the environment of an operating room;

5. the device can be used for pathological slide analysis, and is mainly used for rapid staining treatment and evaluation of cytopathology after fine needle puncture under the guidance of pancreatic lesion ultrasonic endoscope and under similar application scenes.

Drawings

FIG. 1 is an exploded view of the overall structure of the present invention;

FIG. 2 is a schematic view of the internal structure of the present invention;

FIG. 3 is a first view of the kinematic mechanism of the present invention;

FIG. 4 is a second view of the structure of the movement mechanism of the present invention;

FIG. 5 is an exploded view of the pumping mechanism of the present invention;

FIG. 6 is a partial schematic view of the pumping mechanism of the present invention;

FIG. 7 is a first structural view of a pumping mechanism according to the present invention;

FIG. 8 is a schematic view of a quarter-n gear of the present invention;

FIG. 9 is a schematic view of the exterior of the housing of the present invention;

FIG. 10 is a schematic view of the overall structure of the present invention;

in the figure: 1-motion mechanism, 101-loading platform, 102-rack, 103-translation gear, 104-first motor, 105-inclined big gear, 106-inclined small gear, 107-second motor, 108-slide rail, 109-slide groove, 110-slope, 111-liquid discharge hole, 112-buckle, 113-motion mechanism framework, 2-liquid pumping mechanism, 201-spray head, 202-liquid pumping cavity, 203-liquid pumping plug, 204-input pipe, 205-output pipe, 206-merging pipe, 207-one-way valve, 208-driving gear, 209-transmission gear, 210-transmission shaft, 211-nth gear, 212-output gear, 213-transmission rod, 214-third motor, 215-liquid pumping mechanism framework, 3-box, 301-reservoir, 302-box shell, 303-fan, 304-vent, 305-reservoir tube, 306-through hole, 307-reservoir cover, 308-sub-box shell, 309-box cover.

Detailed Description

The invention is described in detail below with reference to the figures and specific embodiments. The following examples are carried out on the premise of the technical scheme of the invention, and detailed embodiments and specific operation processes are given, but the scope of the invention is not limited to the following examples.

Example 1

A pathological slide sequential staining, washing and air drying device is roughly divided into a movement mechanism 1, a liquid pumping mechanism 2 and a box body 3 as shown in figure 1.

As shown in fig. 3 and 4, in the movement mechanism 1 of the present embodiment, a first motor 104, a second motor 107, a tilt pinion 106, a tilt bull gear 105, and a translation gear 103 are mounted on a movement frame 113. Wherein, the tilting pinion 106 is connected with the second motor 107, and can rotate at a low speed under the control of the second motor 107; similarly, the translation gear 103 is connected to the first motor 104, and can rotate at a low speed under the control of the first motor 104. The inclined bull gear 105 is engaged with the inclined pinion gear 106, the top end face of the inclined bull gear 105 is engaged with the slide rail 108 on the lower end face of the loading table 101, and the rack 102 on the lower end face of the loading table 101 is engaged with the translation gear 103. Under the cooperation, when the motor second motor 107 controls the tilting pinion gear 106 to rotate at a low speed, the tilting gearwheel 105 is controlled to rotate around the shaft fixed with the moving rack 113 under the meshing with the tilting pinion gear 106, so that the loading platform 101 matched with the tilting gearwheel is tilted at a certain angle around the shaft; when the first motor 104 controls the translation gear 103 to rotate at a low speed, the rack 102 engaged with the translation gear 103 translates along the tangential direction of the translation gear 103, so as to drive the loading platform 101 to translate for a certain distance under the guidance of the rack 102 and the slide rail 108.

As shown in fig. 4, the loading platform 101 is tilted at a certain angle and translated at a certain distance. In this embodiment, there are 5 protruding slide grooves 109 on the loading platform 101, the slide to be measured can be placed on it, buckle 112 can carry out relatively fixed to the slide to be measured in order to prevent slide to be measured when the loading platform 101 takes place the motion from slipping slide groove 109, loading platform 101 lateral wall is opened has the outage 111 that is used for making unnecessary dyeing waste liquid exhaust, outage 111 can connect the pipeline and lead to the play waste liquid outside this embodiment device, loading platform 101 up end whole slope forms slope 110, it is higher to keep away from outage 111 end, it is lower to be close to outage 111 end, be convenient for the waste liquid to flow into outage 111.

As shown in fig. 5, the liquid pumping mechanism 2 of the present embodiment is included therein. The pumping mechanism frame 215 is provided with a third motor 214, a driving gear 208 and a transmission shaft 210. The driving gear 208 is connected to the third motor 214, and the driving gear 208 can rotate under the control of the third motor 214. The transmission gear 209 is engaged with the driving gear 208, and the transmission gear 209 is fixed with the transmission shaft 210, so that the transmission gear 209 and the transmission shaft 210 can rotate around the central line of the transmission shaft 210 together.

As shown in fig. 8, the gear 211 (which may be called a third gear) is a half n gear of the present embodiment, and the tooth portion of the gear occupies one third of the entire gear circumference.

As shown in fig. 5, 6 and 7, the 3 nth-gear 211 is fixed to the transmission shaft 210, and the one-third tooth portions of the 3 nth-gear 211 are offset from each other, that is, there is no overlap of the peripheral tooth portions of the 3 nth-gear 211 as viewed in the direction of the center line of the transmission shaft 210. The 3 nth-half gears 211 are engaged with the 3 output gears 212, respectively. The output gear 212 is installed on the pump liquid cavity 202, the position, deviating from the center of the gear by a certain distance, of the output gear 212 is hinged with the transmission rod 213, the other end of the transmission rod 213 is hinged with the upper end face of the pump liquid plug 203, and the pump liquid plug 203 can move up and down by a certain distance in the pump liquid cavity 202. In this embodiment, the 3 sets of pump chambers 202 are cylindrical chambers that are relatively closed without a cover, and have an outlet pipe 205 at the lower end and an inlet pipe 204 at the side wall.

As shown in fig. 5, the 3 groups of output pipes 205 are all finally connected with the merging pipe 206 through a through hole 306 on the box shell 302, the two pipes are indirectly provided with a one-way valve 207, so that the liquid can only flow into the merging pipe 206 from the output pipe 205 and can not flow back, and the merging pipe 206 is connected with a plurality of flat nozzle spray heads (spray heads 201); the 3 sets of input pipes 204 are finally connected with 3 liquid storage tank pipes 305 on the liquid storage tank 301 respectively and correspondingly connected with the dye liquor A, the dye liquor B and the clear water, and the input pipe 204 and the liquid storage tank pipes 305 are indirectly provided with the one-way valve 207, so that the liquid can only flow into the input pipe 204 from the liquid storage tank pipes 305 and cannot flow back.

As shown in fig. 5, 6 and 7, when the driving gear 208 rotates at a certain angle at a certain speed under the control of the third motor 214, the transmission gear 209 engaged with the driving gear drives the transmission shaft 210 and the 3 n-th gears 211 fixed thereon to rotate at a certain angle at a certain speed around the center line of the transmission shaft 210. At this time, of the 3 n-th gears and the 3 corresponding to the 3 output gears 212, only 1 of the n-th gears 211 with the teeth meshed with the output gears 212 is engaged, that is, at the same time, only the output gears 212 in this engagement are controlled to rotate so as to control the pump plunger 203 to move up and down in the pump fluid chamber 202 through the transmission rod 213.

In this embodiment, the radius ratio of the nth gear 211 to the output gear 212 is 3:1, and the transmission ratio is 1:3, so that the output gear 212 can complete the whole rotation in the process that the teeth on the nth gear 211 are effectively engaged with the corresponding output gear 212, and the driving rod 213 controls the pump plunger 203 to complete one up-and-down water pumping and water pumping movement in the pump liquid cavity 202. That is, at the same time, the third motor 214 controls the driving gear 208 to rotate a certain angle, a certain liquid in the liquid reservoir 301 enters the pump liquid chamber 202 through the corresponding liquid reservoir pipe 305, the one-way valve 207 and the input pipe 204, the third motor 214 controls the driving gear 208 to continue rotating a certain angle, the liquid in the pump liquid chamber 202 is pressed into the output pipe 205, finally ejected by the sprinkler 201 through the one-way valve 207 and the merging pipe 206, and thereafter, the third motor 214 controls the driving gear 208 to continue rotating, which is the next group of the one-n-th gear 211, the corresponding output gear 212, the pump liquid chamber 202, the pump liquid plug 203 and the transmission rod 213 to work, and the next liquid to be flushed is pumped into the pump liquid chamber 202 and ejected from the flat nozzle sprinkler after being pressed out. The spraying operation process of the dye liquor A, the dye liquor B and the dye liquor C can be completed in sequence.

As shown in fig. 2, fig. 5 and fig. 9, the upper end of the box body 3 in this embodiment has a liquid storage tank 301 capable of storing three liquids, namely, a dye solution a, a dye solution B and clean water, respectively, wherein the volume of the portion for storing clean water is larger so as to meet the larger demand for clean water in the rinsing process. The box 3 includes a box case 302, a sub-box case 308, and a fan 303. In which a fan 303 is disposed at a proper position on an inner side wall of the case housing 302, and a ventilation hole 304 for ventilation is formed on a side wall of the case housing 302 opposite to the fan 303 to quickly air-dry the slide after the staining washing process. The tank shell 302 and the sub-tank shell 308 are assembled to form a relatively sealed tank interior space, as shown in fig. 9. The sub-box shell 308 is provided with a box cover 309 which can be manually opened and closed, after the box cover 309 is opened, a user can finish the loading and unloading of the slide to be tested, and the device is closed during operation; and a liquid storage tank cover 307 which can be manually opened and closed, wherein the liquid storage tank cover 307 is opened, so that a user can supplement liquid for standby to the liquid storage tank 301, and is closed at ordinary times to prevent liquid pollution in the liquid storage tank 301.

As shown in fig. 2, the motion mechanism 1 and the pumping mechanism 2 are both assembled in the box 3, wherein the motion mechanism frame 113, the pumping mechanism frame 215, the pumping chamber 202 and the input pipe 204 and the output pipe 205 thereon are all fixedly assembled with the box 3, and there is no interference between the mechanisms.

In operation of the apparatus of the present embodiment, as shown in fig. 9 and 4, firstly, the user opens the case cover 309, and the loading platform 101 moves horizontally along the slide rail 108 to the side close to the case cover 309 to the vicinity of the case cover 309 under the control of the translation gear 103, at this time, the user can load up to 5 slides to be measured on the slide groove 109. After loading, the loading platform 101 moves horizontally along the slide rail 108 to the side close to the sprinkler head 201 to the lower side of the sprinkler head 201 under the control of the translation gear 103. The third motor 214 controls the driving gear 208 to drive the transmission gear 209 to rotate at a given speed by a certain angle, firstly, a group of liquid transportation parts corresponding to the dye liquor A work, teeth on a corresponding one-nth gear 211 are meshed with a corresponding output gear 212 to be in rotating transmission until the gears are not meshed any more, the pump liquid plug 203 finishes one-time liquid pumping, and the dye liquor A is uniformly sprayed out from the spray head 201 to form a water curtain; meanwhile, the loading platform 101 does reciprocating translation along the slide rail 108 under the control of the translation gear 103 under the action of the sprinkler head 201, so that the water curtain of the dye solution A uniformly flows through the whole 5 slides to be tested, and the dyeing process of the dye solution A is completed. After a certain time, the third motor 214 controls the driving gear 208 to drive the transmission gear 209 to continue rotating for a certain angle at a given speed, a group of liquid transportation parts corresponding to the dye solution B work, teeth on the corresponding nth-half gear 211 are meshed with the corresponding output gear 212 to be rotated and transmitted until the transmission parts are not meshed, the pump liquid plug 203 finishes one-time liquid pumping, and the dye solution B is uniformly sprayed out from the spray head 201 to form a water curtain; meanwhile, the loading platform 101 does reciprocating translation along the slide rail 108 under the control of the translation gear 103 under the action of the sprinkler head 201, so that the water curtain of the dye solution B uniformly flows through the whole 5 slides to be tested, and the dyeing process of the dye solution B is completed. After another time, the loading platform 101 is inclined for a certain angle under the control of the second motor 107, the inclined pinion 106 and the inclined bull gear 105, the third motor 214 controls the driving gear 208 to drive the transmission gear 209 to continue rotating for a certain angle at a given speed, a group of liquid transportation parts corresponding to the clear water work, teeth on a corresponding nth-th gear 211 are meshed with a corresponding output gear 212 to be in rotating transmission until the gears are not meshed, the liquid pumping plug 203 finishes one-time liquid pumping, and the clear water is uniformly sprayed out from the spraying head 201 to form a water curtain; meanwhile, the loading platform 101 is controlled by the translation gear 103 to make reciprocating translation along the slide rail 108 under the control of the translation gear 201 under the condition of inclining for a certain angle, so that the clean water curtain uniformly flows through the whole 5 slides to be detected, the clean water flows down along the inclined slides after being washed, the clean water washing process is completed, and the surface of the slides is washed away to remove floating color. In conclusion, the dyeing and washing processes of the dye liquor A, the dye liquor B and the clear water are completed in sequence. Thereafter, the loading table 101 is returned to the horizontal position under the control of the second motor 107, the inclined pinion gear 106, and the inclined bull gear 105, and the slide is rapidly air-dried by the fan 303. Subsequently, the loading platform 101 moves horizontally to the side close to the box cover 309 along the slide rail 108 under the control of the translation gear 103 to the vicinity of the box cover 309, and the user can take out the processed slide for pathological analysis by opening the box cover 309.

In the above process, after the dye solution and the clear water flow through the slide, the excess solution flows into the slope 110 on the upper end surface of the loading platform 101 from the notches at the two ends of the slide groove 109, flows into the drain hole 111 along the slope, and can be discharged out of the device along with the pipeline. When there is insufficient reserve liquid in the reservoir 301, the reservoir cover 307 may be opened for replenishment.

Example 2

A pathological slide sequential staining, washing and air-drying device comprises a movement mechanism 1, a liquid pumping mechanism 2 and a box body 3. The movement mechanism mainly comprises a loading platform 101, a rack 102, a slide rail 108, a slide groove 109, a slope 110, a liquid discharge hole 111, a buckle 112, a first motor 104, a second motor 107, a movement mechanism frame 113, a translation gear 103, an inclined pinion 106 and an inclined bull gear 105. The loading table 101 has a slide groove 109, a slope 110, and a drain hole 111 on its upper surface. The slide groove 109 is provided at both sides with catches 112 for preventing the slide from moving. The lower surface of the loading table 101 is provided with a rack 102, and is matched with an inclined bull gear 105 through a groove (a slide rail 108). The rack 102 is engaged with a translation gear 103, and the tilt bull gear 105 is engaged with a tilt pinion gear 106. The translation gear 103 and the tilt gear 105 are coaxial and are both fixed to the exercise machine frame 113. The first motor 104 drives the translation gear 103 to rotate, and the second motor 107 drives the tilt pinion 106 to rotate. The translation gear 103 is engaged with the rack 102 on the lower surface of the loading table, and when the translation gear 103 rotates, the rotation is converted into displacement through the engagement of the two, so that the loading table 101 can be translated in the horizontal direction. The inclined gearwheel 105 is engaged with a recess on the lower surface of the loading table 101, and when the inclined gearwheel 105 rotates, the loading table 101 is driven to rotate by a certain corresponding angle, so that the loading table 101 can rotate by a certain angle. The translation and rotation of the loading table 101 are relatively independent and can be accomplished by translation and rotation, respectively.

The liquid pumping mechanism 2 mainly comprises a liquid pumping mechanism framework 215, a third motor 214, a driving gear 208, a transmission gear 209, an n-th gear 211, a transmission shaft 210, a liquid pumping cavity 202, an output gear 212, a one-way valve 207, a transmission rod 213, a liquid pumping plug 203, an input pipe 204 and an output pipe 205. The transmission gear 209 and three nth gears 211 (in this embodiment, one third gears) are located on the same transmission shaft 210, and the transmission shaft 210 is fixed on a pumping mechanism frame 215. The third motor 214 drives the driving gear 208 to mesh with the transmission gear 209. Each third gear meshes with an output gear 212. The output gear 212 is eccentrically connected to a transmission rod 213. The lower part of the transmission rod 213 is directly connected with a pump liquid plug 203 in the pump liquid cavity 202, and the pump liquid plug 203 can slide up and down in the pump liquid cavity 203. The front and the back of the pump liquid cavity 203 are respectively provided with an output hole and an input hole which are connected with an input pipe and an output pipe. The driving gear 208 is driven by the third motor 214 to be meshed with the driving transmission gear 209, the rear transmission gear 209 is meshed with and drives a third gear, and the last third gear is meshed with and drives the output gear 212 to rotate and drive the transmission rod 213 on the output gear 212 to move up and down in the pump liquid plug 203.

Only one third of the circumference of one third of the gear is provided with gear teeth. The transmission gear 209 is meshed at the gear tooth part of one third of the gears to drive one third of the gears to rotate. In the cogless portion, one third of the gears are stationary and not driven in mesh by the drive gear 209. When one-third of the gears are driven to rotate by engagement, the output gear 212 is driven to rotate accordingly. The driving rod 213 of the output gear 212 presses up and down in the pump plug 203 to pump the liquid in the pump chamber 202 through the output pipe 205. When one-third of the gears are at rest, drive link 213 is at the lowest point, i.e., the lowest end of pump fluid chamber 202, and no fluid is pumped from pump fluid chamber 202. When the transmission gear 209 rotates within the range of 0-120 degrees, the first third gear is meshed and driven to rotate so as to pump out the first dye solution; when the transmission gear 209 rotates within the range of 120-240 degrees, the transmission gear is meshed with and drives a second one-third gear to rotate so as to pump out a second dye solution; the transmission gear 209 is meshed to drive the third gear to rotate when rotating within the range of 240-360 degrees so as to pump out the third dye solution. By means of the design, different dye liquids can be pumped at different times. The liquid pumping mechanism 2 is provided with five duckbill-shaped spraying heads 201, and liquid is in a water curtain shape when the liquid is sprayed.

The case 3 is mainly composed of a case 302, a vent hole 306, a sub-case 308, a case cover 309, a reservoir cover 307, a reservoir 301, a fan 303, a through hole 306, and a reservoir pipe 305. A vent hole 306 is provided in the case housing 302. The tank 301 is used for storing dye liquor, and the tank pipe 305 is connected with the input pipe 204 through the one-way valve 207. The liquid in the reservoir 301 reaches the dye liquor spraying device (spraying head 201) through the output pipe 205, and then the dye liquor is sprayed. A fan 303 is located on the side wall of the case for air drying the slides.

In the present invention, it should be noted that the terms "first", "second" and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. It will be readily apparent to those skilled in the art that various modifications to these embodiments may be made, and the generic principles described herein may be applied to other embodiments without the use of the inventive faculty. Therefore, the present invention is not limited to the above embodiments, and those skilled in the art should make improvements and modifications within the scope of the present invention based on the disclosure of the present invention.

Claims (10)

1. The utility model provides a pathological slide sequential staining washes air-dry device which characterized in that includes:

a moving mechanism (1) for moving the slide;

a liquid pumping mechanism (2) for spraying liquid onto the slide;

a case (3) for storing liquid and air-drying the slide;

the moving mechanism (1) comprises a loading platform (101), a translation component for driving the loading platform (101) to translate and a rotating component for driving the loading platform (101) to rotate;

the liquid pumping mechanism (2) comprises a spraying head (201), a plurality of sets of liquid pumping components for driving the spraying head (201) to spray and adjusting components for controlling the opening and closing of each liquid pumping component;

a plurality of liquid storage tanks (301) are arranged on the box body (3), different dye liquor or clean water is filled in each liquid storage tank (301), and each liquid storage tank (301) is correspondingly connected with a set of pump liquid components;

the moving mechanism (1) and the liquid pumping mechanism (2) are arranged on the box body (3), and an air drying assembly is arranged on the box body (3).

2. The pathological slide sequential staining, rinsing and air-drying device according to claim 1, wherein the translational assembly comprises a rack (102), a translational gear (103) and a first motor (104);

the rack (102) is arranged on the lower surface of the loading platform (101), the translation gear (103) is meshed with the rack (102), and the translation gear (103) is connected with the first motor (104).

3. The pathological slide sequential staining, washing and air-drying device according to claim 1, wherein the rotating assembly comprises an inclined large gear (105), an inclined small gear (106) and a second motor (107), the inclined large gear (105) is matched with a slide rail (108) on the lower surface of the loading table (101), the inclined large gear (105) is meshed with the inclined small gear (106), and the inclined small gear (106) is connected with the second motor (107).

4. The pathological slide sequential staining, washing and air-drying device according to claim 3, wherein the top of the inclined bull gear (105) is flush and is clamped on the slide rail (108).

5. The pathological slide sequential staining, washing and air-drying device according to claim 1, wherein the pump liquid assembly comprises a pump liquid cavity (202), a pump liquid plug (203), an input tube (204), an output tube (205) and a merging tube (206), the pump liquid cavity (202) is connected with the liquid storage tank (301) through the input tube (204), the pump liquid cavity (202) is connected with the merging tube (206) through the output tube (205), the spraying head (201) is arranged on the merging tube (206), and the pump liquid plug (203) is arranged in the pump liquid cavity (202) and connected with the adjusting assembly.

6. The pathological slide sequential staining, washing and air-drying device according to claim 5, wherein a check valve (207) for preventing liquid from flowing backwards is arranged between the liquid storage tank (301) and the input pipe (204) and between the output pipe (205) and the merging pipe (206).

7. The pathological slide sequential staining, rinsing and air-drying device according to claim 1, wherein the adjusting assembly comprises a driving gear (208), a transmission gear (209), a transmission shaft (210), a nth gear (211), an output gear (212), a transmission rod (213) and a third motor (214);

the driving gear (208) is meshed with the transmission gear (209) and is connected with the third motor (214), the transmission gear (209) is fixedly connected to the transmission shaft (210), n times of gears (211) with mutually staggered tooth parts are fixed on the transmission shaft (210), the tooth part of each time of n times of gears (211) is meshed with one output gear (212), and each output gear (212) is connected with one set of pump liquid assembly through a transmission rod (213);

and n is an integer of more than 2.

8. The pathological slide sequential staining, washing and air-drying device according to claim 1, wherein the upper surface of the loading platform (101) is provided with a slide groove (109), a slope (110) and a drain hole (111);

the slide groove (109) is provided with buckles (112) on two sides, the slide groove (109) is arranged on a slope (110), and the liquid discharge hole (111) is arranged on the side wall of the loading platform (101) and is positioned on the lower side of the slope (110).

9. The pathological slide sequential staining, rinsing and air-drying device according to claim 1, wherein the pump mechanism (2) comprises five duckbill spray heads (201);

three liquid storage tanks (301) are arranged on the box body (3), and dye liquor A, dye liquor B and clear water are sequentially stored in the three liquid storage tanks (301);

the box (3) still include hollow box shell (302), motion (1) sets up in box shell (302), air-dry subassembly including setting up fan (303) in box shell (302), ventilation hole (304) have been seted up to the one side relative with fan (303) on box shell (302).

10. A pathological slide sequential staining washing and air-drying method, which is carried out by using the pathological slide sequential staining washing and air-drying device according to any one of claims 1-9, and comprises the following steps:

s1: loading a slide to be tested on a loading table (101), and translating the loading table (101) to the lower part of a spraying head (201) by using a translation assembly;

s2: controlling the starting of the first set of pump liquid components by using the adjusting component, spraying the dye liquid in the first liquid storage tank (301) from the spraying head (201), and simultaneously utilizing the translation component to make the loading platform (101) perform reciprocating translation under the spraying head (201);

s3: controlling the next set of pump liquid components to start by using the adjusting component, spraying the dye liquid in the next liquid storage tank (301) from the spraying head (201), and simultaneously utilizing the translation component to make the loading platform (101) perform reciprocating translation under the spraying head (201);

s4: repeating the step S3 until clear water needs to be pumped;

s5: the loading table (101) is inclined by using a rotating assembly, a liquid pumping assembly connected with a liquid storage tank (301) for storing clean water is started by using an adjusting assembly, the clean water is sprayed out of the spraying head (201), and the loading table (101) is translated back and forth by using a translation assembly under the condition of inclination;

s6: the loading table (101) is returned to the horizontal by the rotation means, and the slide is air-dried by the air-drying means.

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