CN113870971A - Intelligent recommendation method for liver and gallbladder damp-heat medicine formula - Google Patents
Intelligent recommendation method for liver and gallbladder damp-heat medicine formula Download PDFInfo
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Abstract
The invention discloses an intelligent recommendation method for a liver and gallbladder damp-heat medicine formula, which comprises the following steps of 1: constructing a formula module, wherein the formula module is used for storing basic information of the existing liver and gallbladder damp-heat medicine formula; step 2: constructing a formula basic research module for storing research conclusions of liver and gallbladder damp-heat medicine formulas for carrying out formula basic research, wherein the research conclusions comprise symptomatic effect rating, side effect categories and side effect ratings under various categories; and step 3: the processing module comprehensively sequences the formula modules based on the research conclusion of the formula basic research module; and 4, step 4: and intelligently outputting a recommended formula of the liver and gallbladder damp-heat medicine formula according to the comprehensive sorting result by selecting keywords of basic data of the medicine formula. The invention adopts systematic thinking, carries out recommendation sequencing on the liver and gallbladder damp-heat medicine formula based on the existing research results, and dynamically updates the intelligent recommendation system based on the formula basic research.
Description
Technical Field
The invention belongs to the field of traditional Chinese medicine, and particularly relates to an intelligent recommendation method for a liver and gallbladder damp-heat medicine formula.
Background
The pattern of damp-heat in the liver and gallbladder is caused by the dysfunction of damp-heat in the liver and gallbladder, and is caused by the dysfunction of the spleen and stomach in transportation and transformation, which leads to the generation of damp-turbidity in the interior and the long-term transformation of heat into heat in the liver and gallbladder. Generally caused by three aspects: firstly, the external damp-heat evil, such as autumn with heavy damp-heat; secondly, overeating spicy food, fat, sweet and thick taste and the like; third, it is commonly seen in young people with irregular diet and high working pressure due to the dysfunction of the spleen and stomach in transportation and transformation.
The pressure of modern people and irregular diet are more and more people with severe or mild syndrome of damp-heat in liver and gallbladder. The damp-heat in the liver and gallbladder may cause dry mouth, bitter taste in mouth, eczema, acute hepatitis, acute cholecystitis, and acute urethritis. The traditional Chinese medicine has numerous prescriptions for damp-heat in liver and gallbladder, for example, the Huangdi's classic points out: the liver-qi heat may cause the gallbladder to discharge bitter taste, i.e., bitter taste means the internal disease. The bitter taste is mainly caused by the following conditions: bitter taste in mouth is obvious, body feels fatigue, mouth is not thirsty, tongue is red, tongue coating is yellow and thick and greasy, pulse is forceful or rapid. The following can be used: 10 g of bupleurum, 5 g of gentian, 8 g of wrinkled gianthyssop herb (added later), 6 g of round cardamom seed (added later), 10 g of grassleaf sweelflag rhizome, 15 g of abrus herb, 10 g of virgate wormwood herb, 12 g of yam rhizome, 20 g of raw coix seed and 6 g of liquorice. Adding water and decocting to 300 ml, and taking 2 times a day with warm water.
However, the diversity of the traditional Chinese medicine prescription for treating damp-heat in liver and gallbladder is not favorable for the selection, use and optimization of the prescription.
Disclosure of Invention
The invention aims to solve the technical problem of providing an intelligent recommendation method for liver and gallbladder damp-heat medical formulas, which adopts systematic thinking, carries out recommendation and sequencing on the liver and gallbladder damp-heat medical formulas based on the existing research results, continuously updates the evaluation of the liver and gallbladder damp-heat medical formulas based on the basic research of the formula, dynamically adjusts the recommendation and sequencing of the liver and gallbladder damp-heat medical formulas, and is beneficial for a user to quickly select the formula of the research results based on the basic research of the formula.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows:
an intelligent recommendation method for a liver and gallbladder damp-heat medicine formula comprises the following steps:
step 1: constructing a formula module, wherein the formula module is used for storing basic information of the existing liver and gallbladder damp-heat medicine formula;
step 2: constructing a formula basic research module for storing research conclusions of liver and gallbladder damp-heat medicine formulas for carrying out formula basic research, wherein the research conclusions comprise symptomatic effect rating, side effect categories and side effect ratings under various categories;
and step 3: the processing module comprehensively sequences the formula modules based on the research conclusion of the formula basic research module;
and 4, step 4: and intelligently outputting a recommended formula of the liver and gallbladder damp-heat medicine formula according to the comprehensive sorting result by selecting keywords of basic data of the medicine formula.
Further, the basic data of the liver and gallbladder damp-heat medicine formula in the step 1 comprise numbers, raw materials, parts by weight, preparation and use methods, medical classifications and universality, wherein the numbers are naturally numbered according to a creation sequence, the raw materials, the parts by weight, the preparation and the use methods are all manually input, the medical treatment classifications comprise a first-level classification or a multi-level classification and provide indefinite options, the universality is used for inputting real numbers which are not less than 1, and when the universality has no input value, a default value is 1.
Wherein, if the liver and gallbladder damp-heat medical formula for carrying out the basic research of the formula in the step 2 is not in the existing liver and gallbladder damp-heat medical formula in the step 1, the formula module needs to be updated, and the basic data of the liver and gallbladder damp-heat medical formula for carrying out the basic research of the formula in the step 2 is added and stored in the formula module.
Preferably, the symptomatic effect rating in step 2 comprises very good, normal and poor and the side effect rating comprises very severe, normal and not severe.
Further, in the step 3, the ranking is performed according to the formula recommendation index comprehensive score, the higher the recommendation index comprehensive score is, the closer the ranking is, the lower the recommendation index comprehensive score is, and the closer the ranking is, the formula of the recommendation index comprehensive score is as follows:
wherein S isiIndicates a recommended index comprehensive score, n, of the liver and gallbladder damp-heat medicinal formula with the number iiIndicates the number of research trials conducted on the pharmaceutical formulation of damp-heat in the liver and gallbladder, numbered i,
Eijthe method comprises the following steps of (1) representing symptomatic effect scores obtained in a j study test of a liver and gall damp-heat medicinal formula with the number of i, wherein the symptomatic effect score is 100 when the symptomatic effect is very good, the symptomatic effect score is 80 when the symptomatic effect score is good, the symptomatic effect score is 60 when the symptomatic effect score is general, and the symptomatic effect score is 40 when the symptomatic effect score is poor;
mijthe number of types of adverse side effects, W, evaluated in the j-th study of the pharmaceutical formulation for damp-heat in the liver and gallbladder, numbered iijxThe importance percentage of the x side effect category evaluated in the j study test of the liver and gallbladder damp-heat medicinal formula with the number of i is represented, and W is more than or equal to 0ijx1 or less, and
kijthe quantitative factor of the side effect evaluated in the j study test of the liver and gallbladder damp-heat medicine formula is shown asijWhen 1, kij1, when mijWhen 2 or 3, kij1.2, mijWhen is 4 or 5, kij1.5, mijWhen k is not less than 6ij＝1.8；
BijxThe medicinal formula for treating damp-heat in liver and gallbladder is represented by the number i, and the side effect is scored under the x side effect category evaluated in the j study test, wherein the corresponding side effect score is 100 when the side effect is rated to be very serious, the corresponding side effect score is 80 when the side effect is rated to be serious, the corresponding side effect score is 60 when the side effect is generally rated, and the corresponding side effect score is 40 when the side effect is not serious.
Preferably, the universality value in formula (1) is dynamically updated based on the increase of the number of research trial evaluations in step 2.
Further preferably, the general calculation formula in formula (1) is:
yi(j+1)＝yi+a×ni (2)
wherein, yijThe universality value of the liver and gallbladder damp-heat medicine formula with the number i in the j research test is shown, yi shows the universality value of the liver and gallbladder damp-heat medicine formula with the number i in the formula module, and a shows the universality factor of the research test times and is a constant.
Preferably, a is 0.01.
Furthermore, in the step 4, while the recommended formulas of the liver and gallbladder damp-heat medical formulas are intelligently output according to the comprehensive sorting result, each recommended formula is displayed, and the formulas related to the displayed recommended formula are displayed in the related module according to the comprehensive sorting result.
Preferably, the basis for judging whether the two formulas are related formulas by the related module comprises the following steps that (1) the raw materials are the same in parts by weight, and the preparation methods are different; ② the raw materials have the same preparation method and different parts by weight.
Compared with the prior art, the invention has the following beneficial effects:
the invention aims to solve the technical problem of providing an intelligent recommendation method for liver and gallbladder damp-heat medical formulas, which adopts systematic thinking, carries out recommendation and sequencing on the liver and gallbladder damp-heat medical formulas based on the existing research results, continuously updates the evaluation of the liver and gallbladder damp-heat medical formulas based on the basic research of the formula, dynamically adjusts the recommendation and sequencing of the liver and gallbladder damp-heat medical formulas, and is beneficial for a user to quickly select the formula of the research results based on the basic research of the formula.
1. The invention arranges a plurality of personalized liver and gallbladder damp-heat formulas, intelligently realizes the intelligent recommendation of liver and gallbladder damp-heat medicine formulas by a system, and is convenient for a user to make a decision quickly based on the existing research.
2. Based on the conclusion of basic research on the formula, the evaluation of the liver and gallbladder damp-heat medicine formula is updated, the recommended ordering of the liver and gallbladder damp-heat medicine formula is dynamically adjusted, and historical data and research results are combined, so that the method is objective and reliable.
3. The method converts subjective evaluation into quantifiable recommendation index comprehensive scores, can systematically generate recommendation results, saves time for a user to look up a large amount of data, improves working efficiency of the user, and is beneficial to popularization and application of research conclusions.
4. The invention comprehensively considers the combination of symptomatic effect, the quantity and the severity of side effect and the application range of the formula, and comprehensively evaluates the formula recommendation index.
5. The invention intelligently outputs the recommended formula of the liver and gallbladder damp-heat medicine formula according to the comprehensive sequencing result, and simultaneously provides the display of the association scheme, thereby facilitating the system understanding of the research result by the user.
6. The invention has simple system, strong inclusion and high reliability, and is convenient for popularization and application of the liver and gallbladder damp-heat formula.
Drawings
FIG. 1 is a flow chart of an intelligent recommendation method for a liver and gallbladder damp-heat medicine formula of the present invention;
fig. 2 is a flow chart of an optimization scheme of the intelligent liver and gallbladder damp-heat medicinal formula recommendation method.
Detailed Description
The present invention will be further described with reference to the accompanying drawings.
Example 1
As shown in fig. 1, an intelligent recommendation method for a liver and gallbladder damp-heat medicine formula comprises the following steps:
step 1: constructing a formula module, wherein the formula module is used for storing basic information of the existing liver and gallbladder damp-heat medicine formula;
further, the basic data of the liver and gallbladder damp-heat medicine formula in the step 1 comprise numbers, raw materials, parts by weight, preparation and use methods, medical classifications and universality, wherein the numbers are naturally numbered according to a creation sequence, the raw materials, the parts by weight, the preparation and the use methods are all manually input, the medical treatment classifications comprise a first-level classification or a multi-level classification and provide indefinite options, the universality is used for inputting real numbers which are not less than 1, and when the universality has no input value, a default value is 1.
The following list of only 2 formulations, as shown in table 1 and table 2 below, is for the sake of clarity of the description of our solution and should not be taken as limiting the scope of protection.
Table 1 schematic table of liver and gallbladder damp-heat medicine formula 1 in formula module
Table 2 schematic table of liver and gallbladder dampness-heat medicine formula 2 in formula module
Step 2: constructing a formula basic research module for storing research conclusions of liver and gallbladder damp-heat medicine formulas for carrying out formula basic research, wherein the research conclusions comprise symptomatic effect rating, side effect categories and side effect ratings under various categories;
wherein, if the liver and gallbladder damp-heat medical formula for carrying out the basic research of the formula in the step 2 is not in the existing liver and gallbladder damp-heat medical formula in the step 1, the formula module needs to be updated, and the basic data of the liver and gallbladder damp-heat medical formula for carrying out the basic research of the formula in the step 2 is added and stored in the formula module.
Preferably, the symptomatic effect rating in step 2 comprises very good, normal and poor and the side effect rating comprises very severe, normal and not severe.
The basic research on the liver and gallbladder damp-heat medicine formulas 1 and 2 can also be expressed as a liver and gallbladder damp-heat medicine formula 1 and a liver and gallbladder damp-heat medicine formula 2, and the research shows that the specific composition and subsequent fermentation and inclusion treatment of the traditional Chinese medicine raw materials of the liver and gallbladder damp-heat medicine formula 1 are beneficial to improving the curative effect of the liver and gallbladder damp-heat, so that the traditional Chinese medicine raw materials are synergistic, the fermentation and inclusion treatment have the effect of strengthening the curative effect, and the comprehensive evaluation effect is good. However, the study also found that the medicinal formula 1 for treating damp-heat in liver and gallbladder may cause the occurrence of red face and conjunctival congestion, but the medicinal formula is not serious.
For the medicine formula 2 for treating damp-heat in liver and gallbladder, liver soothing and gallbladder smoothing, heat clearing and evil eliminating, spleen tonifying and stomach harmonizing, dampness eliminating and qi circulation promoting are required to treat damp-heat in liver and gallbladder and chest pain, but basic research on the formula finds that the formula raw materials are conventional traditional Chinese medicines for heart, liver and kidney meridians, mainly aims at liver-stomach disharmony, qi depression and unobtrusive treatment for relieving chest pain, and has general comprehensive evaluation effect. In addition, the liver and gallbladder damp-heat medicine formula 2 may cause qi deficiency and stomachache, the probability of the stomachache is 1 time more than that of the qi deficiency, and the liver and gallbladder damp-heat medicine formula 2 is strongly related to the fierceness of the nutgrass galingale rhizome in the medicine formula. The secondary rentals for qi deficiency and stomach pain were rated as general and severe, respectively, and the importance percentages for the side effects of qi deficiency and stomach pain were 1/3 and 2/3, respectively.
And step 3: the processing module comprehensively sequences the formula modules based on the research conclusion of the formula basic research module;
further, in the step 3, the ranking is performed according to the formula recommendation index comprehensive score, the higher the recommendation index comprehensive score is, the closer the ranking is, the lower the recommendation index comprehensive score is, and the closer the ranking is, the formula of the recommendation index comprehensive score is as follows:
wherein S isiIndicates a recommended index comprehensive score, n, of the liver and gallbladder damp-heat medicinal formula with the number iiIndicates the number of research trials conducted on the pharmaceutical formulation of damp-heat in the liver and gallbladder, numbered i,
Eijthe method comprises the following steps of (1) representing symptomatic effect scores obtained in a j study test of a liver and gall damp-heat medicinal formula with the number of i, wherein the symptomatic effect score is 100 when the symptomatic effect is very good, the symptomatic effect score is 80 when the symptomatic effect score is good, the symptomatic effect score is 60 when the symptomatic effect score is general, and the symptomatic effect score is 40 when the symptomatic effect score is poor;
mijthe number of types of adverse side effects, W, evaluated in the j-th study of the pharmaceutical formulation for damp-heat in the liver and gallbladder, numbered iijxThe importance percentage of the x side effect category evaluated in the j study test of the liver and gallbladder damp-heat medicinal formula with the number of i is represented, and W is more than or equal to 0ijx1 or less, and
kijthe quantitative factor of the side effect evaluated in the j study test of the liver and gallbladder damp-heat medicine formula is shown asijWhen 1, kij1, when mijWhen 2 or 3, kij1.2, mijWhen is 4 or 5, kij1.5, mijWhen k is not less than 6ij＝1.8；
BijxThe side effect score of the pharmaceutical formulation of damp-heat in liver and gallbladder under the x side effect category evaluated in the j study test is shown, iThe rating of the use was very severe, the corresponding side effect was scored as 100, when the side effect was rated as severe, the corresponding side effect was scored as 80, when the side effect was rated as general, the corresponding side effect was scored as 60, and when the side effect was rated as not severe, the corresponding side effect was scored as 40.
The conclusion of basic research on the liver and gallbladder damp-heat medicine formula 1 and the liver and gallbladder damp-heat medicine formula 2 is applied, and the recommended comprehensive indexes of the liver and gallbladder damp-heat medicine formula 1 and the liver and gallbladder damp-heat medicine formula 2 are respectively as follows:
S1＝1.2×(80-20)＝72
S2＝1.0×[60-1.2(1/3×60+2/3×80]＝(-28)
and 4, step 4: and intelligently outputting a recommended formula of the liver and gallbladder damp-heat medicine formula according to the comprehensive sorting result by selecting keywords of basic data of the medicine formula.
If the search keyword is 'liver', both the liver and gallbladder damp-heat medicine formula 1 and the liver and gallbladder damp-heat medicine formula 2 are displayed, and because the recommended comprehensive index score of the liver and gallbladder damp-heat medicine formula 1 is higher than that of the liver and gallbladder damp-heat medicine formula 2, the liver and gallbladder damp-heat medicine formula 1 is displayed before the liver and gallbladder damp-heat medicine formula 2.
Example 2
Example 2 differs from example 1 only in that: the universal value in formula (1) is not directly selected from the universal values in the formula module, but increases with the number of research trials.
Specifically, the universality value in formula (1) is dynamically updated based on the increase of the number of research trial evaluations in step 2.
Further preferably, the general calculation formula in formula (1) is:
yi(j+1)＝yi+a×ni (2)
wherein, yijThe general applicability value of the liver and gallbladder damp-heat medicinal formula with the number i in the j research test is shown, yi shows the general applicability value of the liver and gallbladder damp-heat medicinal formula with the number i in the formula module, a shows the general applicability factor of the research test times, and is a constant。
Preferably, a is 0.01.
The second set of basic research on the liver and gallbladder damp-heat medicine formula 1 shows that the comprehensive evaluation effect is still good. However, the damp-heat in liver and gallbladder in the formula 1 may cause dry mouth and tongue, and the symptoms are mild or not serious.
The universality of a liver and gallbladder damp-heat medicine formula 1 and a liver and gallbladder damp-heat medicine formula 2 is updated and respectively:
y12＝1.2+0.01×2＝1.22
y22＝1.0+0.01×1＝1.01
updating the recommended comprehensive indexes of the liver and gallbladder damp-heat medicine formula 1 and the liver and gallbladder damp-heat medicine formula 2, wherein the recommended comprehensive indexes are respectively as follows:
S1’＝1.22×[(80+80)/2-(20+20)/2)]＝73.2
S2’＝1.01×[60-1.2(1/3×60+2/3×80]＝(-28.28)
since the recommended combination index score of the liver and gallbladder damp-heat medicine formula 1 is higher than that of the liver and gallbladder damp-heat medicine formula 2, the liver and gallbladder damp-heat medicine formula 1 is displayed before the liver and gallbladder damp-heat medicine formula 2.
Example 3
Example 3 differs from example 1 only in that: on the basis of intelligently displaying the recommended formula, the related formula is displayed, and a formula basic researcher is assisted to comprehensively know the current research situation of the liver and gallbladder damp-heat medicinal formula.
Specifically, as shown in fig. 2, while the recommended formula of the liver and gallbladder damp-heat medical formula is intelligently output according to the comprehensive ranking result in step 4, each recommended formula is displayed, and the formula associated with the displayed recommended formula is displayed in the association module according to the comprehensive ranking result.
Preferably, the basis for judging whether the two formulas are related formulas by the related module comprises the following steps that (1) the raw materials are the same in parts by weight, and the preparation methods are different; ② the raw materials have the same preparation method and different parts by weight.
Based on the liver and gallbladder damp-heat medicine formula 1, the weight parts of the cogongrass rhizome, the epimedium herb and the rhizoma atractylodis stir-fried with bran are adjusted to form a liver and gallbladder damp-heat medicine formula 3, which is shown in the following table 3.
Table 3 schematic table of liver and gallbladder damp-heat medicine formula 3 in formula module
The liver and gallbladder damp-heat medicine formula 3 is used as the related formula of the liver and gallbladder damp-heat medicine formula 1, and besides the occurrence of the scores according to the recommended comprehensive index in the recommended formula, the liver and gallbladder damp-heat medicine formula 1 is displayed and simultaneously appears in the related formula of the liver and gallbladder damp-heat medicine formula 1.
The formula module, the formula basic research module, the processing module and the related module do not relate to the improvement of a hardware structure, and mainly aim at the improvement of an internal processing algorithm flow.
In the description provided herein, numerous specific details are set forth. It is understood, however, that embodiments of the invention may be practiced without these specific details. In some instances, well-known methods, structures and techniques have not been shown in detail in order not to obscure an understanding of this description.
Similarly, it should be appreciated that in the foregoing description of exemplary embodiments of the invention, various features of the invention are sometimes grouped together in a single embodiment, figure, or description thereof for the purpose of streamlining the disclosure and aiding in the understanding of one or more of the various inventive aspects. However, the disclosed method should not be interpreted as reflecting an intention that: that the invention as claimed requires more features than are expressly recited in each claim. Rather, as the following claims reflect, inventive aspects lie in less than all features of a single foregoing disclosed embodiment. Thus, the claims following the detailed description are hereby expressly incorporated into this detailed description, with each claim standing on its own as a separate embodiment of this invention.
Those skilled in the art will appreciate that the modules or units or groups of devices in the examples disclosed herein may be arranged in a device as described in this embodiment, or alternatively may be located in one or more devices different from the devices in this example. The modules in the foregoing examples may be combined into one module or may be further divided into multiple sub-modules.
Those skilled in the art will appreciate that the modules in the device in an embodiment may be adaptively changed and disposed in one or more devices different from the embodiment. Modules or units or groups in embodiments may be combined into one module or unit or group and may furthermore be divided into sub-modules or sub-units or sub-groups. All of the features disclosed in this specification (including any accompanying claims, abstract and drawings), and all of the processes or elements of any method or apparatus so disclosed, may be combined in any combination, except combinations where at least some of such features and/or processes or elements are mutually exclusive. Each feature disclosed in this specification (including any accompanying claims, abstract and drawings) may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise.
Furthermore, those skilled in the art will appreciate that while some embodiments described herein include some features included in other embodiments, rather than other features, combinations of features of different embodiments are meant to be within the scope of the invention and form different embodiments. For example, in the claims, any of the claimed embodiments may be used in any combination.
As used herein, unless otherwise specified the use of the ordinal adjectives "first", "second", "third", etc., to describe a common object, merely indicate that different instances of like objects are being referred to, and are not intended to imply that the objects so described must be in a given sequence, either temporally, spatially, in ranking, or in any other manner.
While the invention has been described with respect to a limited number of embodiments, those skilled in the art, having benefit of this description, will appreciate that other embodiments can be devised which do not depart from the scope of the invention as described herein. Furthermore, it should be noted that the language used in the specification has been principally selected for readability and instructional purposes, and may not have been selected to delineate or circumscribe the inventive subject matter. Accordingly, many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the appended claims. The present invention has been disclosed in an illustrative rather than a restrictive sense, and the scope of the present invention is defined by the appended claims.
Claims (10)
1. An intelligent recommendation method for a liver and gallbladder damp-heat medicine formula is characterized by comprising the following steps: the method comprises the following steps:
step 1: constructing a formula module, wherein the formula module is used for storing basic information of the existing liver and gallbladder damp-heat medicine formula;
step 2: constructing a formula basic research module for storing research conclusions of liver and gallbladder damp-heat medicine formulas for carrying out formula basic research, wherein the research conclusions comprise symptomatic effect rating, side effect categories and side effect ratings under various categories;
and step 3: the processing module comprehensively sequences the formula modules based on the research conclusion of the formula basic research module;
and 4, step 4: and intelligently outputting a recommended formula of the liver and gallbladder damp-heat medicine formula according to the comprehensive sorting result by selecting keywords of basic data of the medicine formula.
2. The intelligent recommendation method for the pharmaceutical formula of damp-heat in liver and gallbladder according to claim 1, wherein: the basic data of the liver and gallbladder damp-heat medicine formula in the step 1 comprise a serial number, raw materials, parts by weight, preparation and using methods, medical treatment classification and universality, wherein the serial number is naturally numbered according to a creation sequence, the raw materials, the parts by weight, the preparation and the using methods are all manually input, the medical treatment classification comprises primary classification or multi-stage classification, indefinite options are provided, the universality is used for inputting real numbers which are not less than 1, and when the universality has no input value, a default value is 1.
3. The intelligent recommendation method for the pharmaceutical formula of damp-heat in liver and gallbladder according to claim 1, wherein: in the step 2, if the liver and gallbladder damp-heat medicine formula for performing the basic formula research is not in the existing liver and gallbladder damp-heat medicine formula in the step 1, the formula module needs to be updated, and basic data of the liver and gallbladder damp-heat medicine formula for performing the basic formula research in the step 2 is added and stored in the formula module.
4. The intelligent recommendation method for the pharmaceutical formula of damp-heat in liver and gallbladder according to claim 2, wherein: the symptomatic effect rating in step 2 included very good, general and poor, and the side effect rating included very severe, general and not severe.
5. The intelligent recommendation method for the pharmaceutical formula of damp-heat in liver and gallbladder according to claim 4, wherein: in step 3, the ranking is performed according to the formula recommendation index comprehensive scores, the higher the recommendation index comprehensive score is, the closer the ranking is, the lower the recommendation index comprehensive score is, and the closer the ranking is, the recommendation index comprehensive score formula is as follows:
wherein S isiIndicates a recommended index comprehensive score, n, of the liver and gallbladder damp-heat medicinal formula with the number iiIndicates the number of research trials conducted on the pharmaceutical formulation of damp-heat in the liver and gallbladder, numbered i,
Eijthe clinical results show that the symptomatic effect score of the liver and gallbladder damp-heat medicinal formula with the number of i in the j research test, i when the symptomatic effect is very good, the corresponding symptomatic effect score is 100, when the symptomatic effect is rated as good, the corresponding symptomatic effect is rated as 80, when the symptomatic effect is rated as general, the corresponding symptomatic effect is rated as 60, and when the symptomatic effect is rated as poor, the corresponding symptomatic effect is rated as 40;
mijthe number of types of adverse side effects, W, evaluated in the j-th study of the pharmaceutical formulation for damp-heat in the liver and gallbladder, numbered iijxThe importance percentage of the x side effect category evaluated in the j study test of the liver and gallbladder damp-heat medicinal formula with the number of i is represented, and W is more than or equal to 0ijx1 or less, and
kijthe quantitative factor of the side effect evaluated in the j study test of the liver and gallbladder damp-heat medicine formula is shown asijWhen 1, kij1, when mijWhen 2 or 3, kij1.2, mijWhen is 4 or 5, kij1.5, mijWhen k is not less than 6ij＝1.8；
BijxThe medicinal formula for treating damp-heat in liver and gallbladder is represented by the number i, and the side effect is scored under the x side effect category evaluated in the j study test, wherein the corresponding side effect score is 100 when the side effect is rated to be very serious, the corresponding side effect score is 80 when the side effect is rated to be serious, the corresponding side effect score is 60 when the side effect is generally rated, and the corresponding side effect score is 40 when the side effect is not serious.
6. The intelligent recommendation method for the pharmaceutical formula of damp-heat in liver and gallbladder according to claim 5, wherein: the universality value in equation (1) is dynamically updated based on the increase in the number of study trial evaluations in step 2.
7. The intelligent recommendation method for the pharmaceutical formula of damp-heat in liver and gallbladder according to claim 6, wherein: the general calculation formula in formula (1) is:
yi(j+1)＝yi+a×ni (2)
wherein, yijThe universality value of the liver and gallbladder damp-heat medicine formula with the number i in the j research test is shown, yi shows the universality value of the liver and gallbladder damp-heat medicine formula with the number i in the formula module, and a shows the universality factor of the research test times and is a constant.
8. The intelligent recommendation method for the pharmaceutical formula of damp-heat in liver and gallbladder according to claim 7, wherein: and a is 0.01.
9. The intelligent recommendation method for the pharmaceutical formula of damp-heat in liver and gallbladder according to claim 8, wherein: and 4, intelligently outputting recommended formulas of the liver and gallbladder damp-heat medicine formulas according to the comprehensive sorting result, displaying each recommended formula, and displaying the formula associated with the displayed recommended formula in the association module according to the comprehensive sorting result.
10. The intelligent recommendation method for the pharmaceutical formula of damp-heat in liver and gallbladder according to claim 9, wherein: the correlation module judges whether the two formulas are the basis of the correlation formula, wherein the basis comprises the following steps that firstly, the raw materials are the same in parts by weight, and the preparation methods are different; ② the raw materials have the same preparation method and different parts by weight.
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| CN111177117A (en) * | 2019-12-17 | 2020-05-19 | 山东中医药大学第二附属医院 | Traditional Chinese medicine medical record data processing method |
| CN112116978A (en) * | 2020-09-17 | 2020-12-22 | 陕西师范大学 | Method, system and device for recommending rheumatism immunity medicine |
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| CN108122619A (en) * | 2017-12-07 | 2018-06-05 | 济宁医学院 | Zang-Fu syndrome levelling pharmaceutical procedures based on database |
| CN111177117A (en) * | 2019-12-17 | 2020-05-19 | 山东中医药大学第二附属医院 | Traditional Chinese medicine medical record data processing method |
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