CN113599463A - Formula for treating cardiovascular and cerebrovascular diseases and preparation method thereof - Google Patents

Formula for treating cardiovascular and cerebrovascular diseases and preparation method thereof Download PDF

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CN113599463A
CN113599463A CN202110979054.7A CN202110979054A CN113599463A CN 113599463 A CN113599463 A CN 113599463A CN 202110979054 A CN202110979054 A CN 202110979054A CN 113599463 A CN113599463 A CN 113599463A
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parts
ginseng
cerebrovascular diseases
formula
uncaria
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陈保良
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    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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Abstract

The invention discloses a formula for treating cardiovascular and cerebrovascular diseases, which comprises the following components in parts by weight: 8-20 parts of ginseng, 15-60 parts of astragalus membranaceus, 8-15 parts of bighead atractylodes rhizome, 8-15 parts of poria cocos, 15-30 parts of cistanche deserticola, 8-20 parts of epimedium herb, 8-15 parts of prepared rehmannia root, 10-30 parts of tortoise plastron, 8-25 parts of turtle shell, 8-30 parts of concha haliotidis, 8-20 parts of selfheal, 1-5 parts of dragon's blood, 6-15 parts of rhizoma corydalis, 3-10 parts of frankincense, 3-10 parts of myrrh, 8-20 parts of ligusticum chuanxiong hort, 8-15 parts of pseudo-ginseng, 2-8 parts of scorpion, 8-15 parts of earthworm, 2-5 parts of centipede, 8-20 parts of stiff silkworm, 8-25 parts of seaweed, 6-20 parts of trichosanthes kirilowii maxim, 10-30 parts of xiangfu, 5-10 parts of costus root, 8-25 parts of uncaria, 8-15 parts of gastrodia elata, 8-15 parts of angelica sinensis and 8-15 parts of parasitic loranthus, 8-30 parts of caulis spatholobi. The invention has strong functionality and can be widely applied to the technical field of traditional Chinese medicine preparation.

Description

Formula for treating cardiovascular and cerebrovascular diseases and preparation method thereof
Technical Field
The invention relates to the field of traditional Chinese medicine preparation, in particular to a formula for treating cardiovascular and cerebrovascular diseases and a preparation method thereof.
Background
Cardiovascular and cerebrovascular diseases are common frequently-occurring diseases of middle-aged and elderly people, patients often show diseases such as hypertension, coronary heart disease, cerebral arteriosclerosis, cerebral blood supply insufficiency and the like, and the self-care ability of the patients is seriously affected, so that certain economic burden and labor burden are brought to the patients and families of the patients. In the prior art, the treatment means and the auxiliary treatment means are generally combination of Chinese medicines and western medicines, operation, blood vessel flushing and the like, but the methods have the defect that the aim of relieving or curing can not be achieved under the condition that a patient easily accepts the treatment, and particularly for the patient who accepts the treatment for a long time, the methods are psychological burden.
Disclosure of Invention
In order to solve the problems, the invention provides a formula for treating cardiovascular and cerebrovascular diseases, which can not cause drug resistance psychology to patients in the using process and can achieve the aim of healing.
The technical scheme provided by the invention is as follows:
a formula for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by weight:
8-20 parts of ginseng, 15-60 parts of astragalus membranaceus, 8-15 parts of bighead atractylodes rhizome, 8-15 parts of poria cocos, 15-30 parts of cistanche deserticola, 8-20 parts of epimedium herb, 8-15 parts of prepared rehmannia root, 10-30 parts of tortoise plastron, 8-25 parts of turtle shell, 8-30 parts of concha haliotidis, 8-20 parts of selfheal, 1-5 parts of dragon's blood, 6-15 parts of rhizoma corydalis, 3-10 parts of frankincense, 3-10 parts of myrrh, 8-20 parts of ligusticum chuanxiong hort, 8-15 parts of pseudo-ginseng, 2-8 parts of scorpion, 8-15 parts of earthworm, 2-5 parts of centipede, 8-20 parts of stiff silkworm, 8-25 parts of seaweed, 6-20 parts of trichosanthes kirilowii maxim, 10-30 parts of rhizoma cyperi, 5-10 parts of elecampane, 8-25 parts of uncaria, 8-15 parts of angelica sinensis, 8-15 parts of parasitic loranthus, 8-30 parts of caulis spatholobi.
Further, the feed comprises the following components in parts by weight:
8 parts of ginseng, 15 parts of astragalus membranaceus, 8 parts of bighead atractylodes rhizome, 8 parts of poria cocos, 15 parts of cistanche, 8 parts of epimedium herb, 8 parts of prepared rehmannia root, 10 parts of tortoise plastron, 8 parts of turtle shell, 8 parts of concha haliotidis, 8 parts of selfheal, 1 part of dragon's blood, 6 parts of rhizoma corydalis, 3 parts of frankincense, 3 parts of myrrh, 8-parts of ligusticum wallichii, 8 parts of pseudo-ginseng, 2 parts of scorpion, 8 parts of earthworm, 2 parts of centipede, 8 parts of stiff silkworm, 8 parts of seaweed, 6 parts of trichosanthes kirilowii maxim, 10 parts of rhizoma cyperi, 5 parts of elecampane, 8 parts of uncaria, 8 parts of gastrodia elata, 8 parts of angelica sinensis, 8 parts of parasitic loranthus and 8 parts of caulis spatholobi.
Further, the feed comprises the following components in parts by weight:
20 parts of ginseng, 60 parts of astragalus membranaceus, 15 parts of bighead atractylodes rhizome, 15 parts of poria cocos, 30 parts of cistanche, 20 parts of epimedium herb, 15 parts of prepared rehmannia root, 30 parts of tortoise plastron, 25 parts of turtle shell, 30 parts of concha haliotidis, 20 parts of selfheal, 5 parts of dragon's blood, 15 parts of rhizoma corydalis, 10 parts of frankincense, 10 parts of myrrh, 20 parts of ligusticum wallichii, 15 parts of pseudo-ginseng, 8 parts of scorpion, 15 parts of earthworm, 5 parts of centipede, 20 parts of stiff silkworm, 25 parts of seaweed, 20 parts of trichosanthes kirilowii maxim, 30 parts of rhizoma cyperi, 10 parts of elecampane, 25 parts of uncaria, 15 parts of gastrodia elata, 15 parts of angelica sinensis, 15 parts of parasitic loranthus and 30 parts of caulis spatholobi.
Further, the feed comprises the following components in parts by weight:
14 parts of ginseng, 35 parts of astragalus membranaceus, 12 parts of bighead atractylodes rhizome, 12 parts of poria cocos, 22 parts of cistanche, 14 parts of epimedium herb, 11 parts of prepared rehmannia root, 20 parts of tortoise plastron, 13 parts of turtle shell, 19 parts of abalone shell, 14 parts of selfheal, 3 parts of dragon's blood, 11 parts of rhizoma corydalis, 6.5 parts of frankincense, 6.5 parts of myrrh, 14 parts of ligusticum chuanxiong hort, 11 parts of pseudo-ginseng, 5 parts of scorpion, 11 parts of earthworm, 3.5 parts of centipede, 14 parts of stiff silkworm, 11 parts of seaweed, 13 parts of snakegourd fruit, 20 parts of rhizoma cyperi, 7.5 parts of elecampane, 13 parts of uncaria, 13 parts of gastrodia elata, 12 parts of angelica sinensis, 13 parts of parasitic loranthus and 19 parts of suberect spatholobus stem.
The invention also provides a technical scheme that:
a preparation method of a formula for treating cardiovascular and cerebrovascular diseases is provided, wherein the formula is the above formula, and the preparation method comprises the following preparation processes:
respectively mixing a certain amount of ginseng, astragalus root 35, bighead atractylodes rhizome, poria cocos, cistanche deserticola, epimedium herb, prepared rehmannia root, tortoise plastron, turtle shell, abalone shell, selfheal, dragon's blood, rhizoma corydalis, frankincense, myrrh, ligusticum wallichii, pseudo-ginseng, scorpion, earthworm, centipede, stiff silkworm, seaweed, snakegourd fruit, rhizoma cyperi, costustoot, uncaria, gastrodia elata, angelica sinensis, parasitic loranthus and suberect spatholobus stem, grinding into powder with grinding equipment with certain fineness, and then mixing with honey to obtain pills.
Further, the grinding fineness of the powder is 50-100 meshes.
Compared with the prior art, the invention has the advantages that:
by adopting the formula provided by the invention, the aim of curing cardiovascular and cerebrovascular diseases is achieved, and the drug resistance psychology of a patient is not generated, so that the functional performance is strong;
the technology provided by the invention is convenient to take, can realize the function of independent taking for patients of different ages, reduces the nursing burden, and has stronger practicability.
Detailed Description
The present invention will be described in further detail with reference to examples.
The formula for treating the cardiovascular and cerebrovascular diseases comprises the following components in parts by weight:
8-20 parts of ginseng, 15-60 parts of astragalus membranaceus, 8-15 parts of bighead atractylodes rhizome, 8-15 parts of poria cocos, 15-30 parts of cistanche deserticola, 8-20 parts of epimedium herb, 8-15 parts of prepared rehmannia root, 10-30 parts of tortoise plastron, 8-25 parts of turtle shell, 8-30 parts of concha haliotidis, 8-20 parts of selfheal, 1-5 parts of dragon's blood, 6-15 parts of rhizoma corydalis, 3-10 parts of frankincense, 3-10 parts of myrrh, 8-20 parts of ligusticum chuanxiong hort, 8-15 parts of pseudo-ginseng, 2-8 parts of scorpion, 8-15 parts of earthworm, 2-5 parts of centipede, 8-20 parts of stiff silkworm, 8-25 parts of seaweed, 6-20 parts of trichosanthes kirilowii maxim, 10-30 parts of rhizoma cyperi, 5-10 parts of elecampane, 8-25 parts of uncaria, 8-15 parts of angelica sinensis, 8-15 parts of parasitic loranthus, 8-30 parts of caulis spatholobi.
The process of preparing the medicine for taking by using the formula comprises the following steps:
respectively mixing a certain amount of ginseng, astragalus root 35, bighead atractylodes rhizome, poria cocos, cistanche deserticola, epimedium herb, prepared rehmannia root, tortoise plastron, turtle shell, abalone shell, selfheal, dragon's blood, rhizoma corydalis, frankincense, myrrh, ligusticum wallichii, pseudo-ginseng, scorpion, earthworm, centipede, stiff silkworm, seaweed, snakegourd fruit, rhizoma cyperi, costustoot, uncaria, gastrodia elata, angelica sinensis, parasitic loranthus and suberect spatholobus stem, grinding into powder with grinding equipment with certain fineness, and then mixing with honey to obtain pills.
In the specific preparation process, carapax et Plastrum Testudinis, carapax Trionycis, Scorpio, Scolopendra, Bombyx Batryticatus, Olibanum, and Myrrha can be processed to improve drug effect. And the caulis spatholobi is decocted into paste, added into other components and prepared into pills by adding honey.
The method provided by the invention is adopted to prepare the medicine, so that the pill medicine is achieved. The medicine is convenient to take when being applied to the treatment process of cardiovascular and cerebrovascular diseases.
Example one
A formula for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by weight:
8 parts of ginseng, 15 parts of astragalus membranaceus, 8 parts of bighead atractylodes rhizome, 8 parts of poria cocos, 15 parts of cistanche, 8 parts of epimedium herb, 8 parts of prepared rehmannia root, 10 parts of tortoise plastron, 8 parts of turtle shell, 8 parts of concha haliotidis, 8 parts of selfheal, 1 part of dragon's blood, 6 parts of rhizoma corydalis, 3 parts of frankincense, 3 parts of myrrh, 8-parts of ligusticum wallichii, 8 parts of pseudo-ginseng, 2 parts of scorpion, 8 parts of earthworm, 2 parts of centipede, 8 parts of stiff silkworm, 8 parts of seaweed, 6 parts of trichosanthes kirilowii maxim, 10 parts of rhizoma cyperi, 5 parts of elecampane, 8 parts of uncaria, 8 parts of gastrodia elata, 8 parts of angelica sinensis, 8 parts of parasitic loranthus and 8 parts of caulis spatholobi.
In the process of preparing the medicine for treating the cardiovascular and cerebrovascular diseases by using the components, the following operation processes are adopted:
respectively mixing ginseng, astragalus root 35, bighead atractylodes rhizome, poria cocos, cistanche deserticola, epimedium herb, prepared rehmannia root, tortoise plastron, turtle shell, abalone shell, selfheal, dragon's blood, rhizoma corydalis, frankincense, myrrh, ligusticum wallichii, pseudo-ginseng, scorpion, earthworm, centipede, stiff silkworm, seaweed, snakegourd fruit, rhizoma cyperi, costustoot, uncaria, gastrodia elata, angelica sinensis, parasitic loranthus and suberect spatholobus stem, grinding into powder of 50 meshes by using grinding equipment, and then mixing with honey to obtain pills.
Example two
A formula for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by weight:
20 parts of ginseng, 60 parts of astragalus membranaceus, 15 parts of bighead atractylodes rhizome, 15 parts of poria cocos, 30 parts of cistanche, 20 parts of epimedium herb, 15 parts of prepared rehmannia root, 30 parts of tortoise plastron, 25 parts of turtle shell, 30 parts of concha haliotidis, 20 parts of selfheal, 5 parts of dragon's blood, 15 parts of rhizoma corydalis, 10 parts of frankincense, 10 parts of myrrh, 20 parts of ligusticum wallichii, 15 parts of pseudo-ginseng, 8 parts of scorpion, 15 parts of earthworm, 5 parts of centipede, 20 parts of stiff silkworm, 25 parts of seaweed, 20 parts of trichosanthes kirilowii maxim, 30 parts of rhizoma cyperi, 10 parts of elecampane, 25 parts of uncaria, 15 parts of gastrodia elata, 15 parts of angelica sinensis, 15 parts of parasitic loranthus and 30 parts of caulis spatholobi.
The preparation process is the same as in example one, but the fineness of the ground powder is 100 mesh.
EXAMPLE III
A formula for treating cardiovascular and cerebrovascular diseases comprises the following components in parts by weight:
14 parts of ginseng, 35 parts of astragalus membranaceus, 12 parts of bighead atractylodes rhizome, 12 parts of poria cocos, 22 parts of cistanche, 14 parts of epimedium herb, 11 parts of prepared rehmannia root, 20 parts of tortoise plastron, 13 parts of turtle shell, 19 parts of abalone shell, 14 parts of selfheal, 3 parts of dragon's blood, 11 parts of rhizoma corydalis, 6.5 parts of frankincense, 6.5 parts of myrrh, 14 parts of ligusticum chuanxiong hort, 11 parts of pseudo-ginseng, 5 parts of scorpion, 11 parts of earthworm, 3.5 parts of centipede, 14 parts of stiff silkworm, 11 parts of seaweed, 13 parts of snakegourd fruit, 20 parts of rhizoma cyperi, 7.5 parts of elecampane, 13 parts of uncaria, 13 parts of gastrodia elata, 12 parts of angelica sinensis, 13 parts of parasitic loranthus and 19 parts of suberect spatholobus stem.
The preparation process is the same as in the first example.
Example four
In this example, the treatment effects of examples one to three were verified.
Firstly, due to the unique characteristics of the preparation process, the prepared medicine can keep the original medicine property, and is convenient for patients to take.
Then, the techniques provided by the present invention are classified into four categories for verification.
Class one: patients with clinical hypertension in three age groups of 50 years old, 60 years old and 70 years old are respectively selected as clinical experimental subjects, each age group is 10 persons and is divided into an experimental group and a control group, wherein the experimental group takes the formula provided by the invention, and the control group takes antihypertensive drugs common in the prior art.
The observation of three months shows that the taking of the medicine provided by the invention can realize the relieving function to a greater extent, the mild hypertension patient is cured, and the patient is easy to accept in the taking process, thereby improving the treatment efficiency. However, the control group has an unobvious treatment effect and increases the cost in the treatment process due to the reasons of difficult administration, poor drug properties and the like.
Class II:
patients with coronary heart disease in three age groups of 50 years old, 60 years old and 70 years old are selected as clinical experimental subjects respectively, each age group is 10 people and is divided into an experimental group and a control group, wherein the experimental group takes the formula provided by the invention, and the control group takes antihypertensive drugs common in the prior art.
The observation of four months shows that the medicine provided by the invention can realize the function of relieving to a greater extent when being taken, patients with mild coronary heart disease are cured, and the patients are easy to accept in the taking process, thereby improving the treatment efficiency. However, the control group has an unobvious treatment effect and increases the cost in the treatment process due to the reasons of difficult administration, poor drug properties and the like.
Class three:
patients with cerebral arteriosclerosis and cerebral ischemia in three age groups of 50 years old, 60 years old and 70 years old are selected as clinical experimental subjects respectively, each age group is 10 patients and is divided into an experimental group and a control group, wherein the experimental group takes the formula provided by the invention, and the control group takes antihypertensive drugs common in the prior art.
The observation of four months shows that the medicine provided by the invention can realize the function of relieving to a greater extent when being taken, patients with mild diseases are cured, and the patients are easy to accept in the taking process, thereby improving the treatment efficiency. However, the control group has unobvious treatment effect due to difficult administration, poor drug properties and other reasons, and the cost in the treatment process is increased.
In conclusion, the formula provided by the invention can achieve the purposes of treating hypertension, coronary heart disease, cerebral arteriosclerosis and cerebral ischemia, and has strong functionality and wide application range.
The present invention and its embodiments have been described above, but the description is not limited thereto, and the embodiments shown in the examples are only one of the embodiments of the present invention, and the actual disclosure is not limited thereto. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (6)

1. The formula for treating the cardiovascular and cerebrovascular diseases is characterized by comprising the following components in parts by weight:
8-20 parts of ginseng, 15-60 parts of astragalus membranaceus, 8-15 parts of bighead atractylodes rhizome, 8-15 parts of poria cocos, 15-30 parts of cistanche deserticola, 8-20 parts of epimedium herb, 8-15 parts of prepared rehmannia root, 10-30 parts of tortoise plastron, 8-25 parts of turtle shell, 8-30 parts of concha haliotidis, 8-20 parts of selfheal, 1-5 parts of dragon's blood, 6-15 parts of rhizoma corydalis, 3-10 parts of frankincense, 3-10 parts of myrrh, 8-20 parts of ligusticum chuanxiong hort, 8-15 parts of pseudo-ginseng, 2-8 parts of scorpion, 8-15 parts of earthworm, 2-5 parts of centipede, 8-20 parts of stiff silkworm, 8-25 parts of seaweed, 6-20 parts of trichosanthes kirilowii maxim, 10-30 parts of rhizoma cyperi, 5-10 parts of elecampane, 8-25 parts of uncaria, 8-15 parts of angelica sinensis, 8-15 parts of parasitic loranthus, 8-30 parts of caulis spatholobi.
2. The formula for treating cardiovascular and cerebrovascular diseases according to claim 1, which comprises the following components in parts by weight:
8 parts of ginseng, 15 parts of astragalus membranaceus, 8 parts of bighead atractylodes rhizome, 8 parts of poria cocos, 15 parts of cistanche, 8 parts of epimedium herb, 8 parts of prepared rehmannia root, 10 parts of tortoise plastron, 8 parts of turtle shell, 8 parts of concha haliotidis, 8 parts of selfheal, 1 part of dragon's blood, 6 parts of rhizoma corydalis, 3 parts of frankincense, 3 parts of myrrh, 8-parts of ligusticum wallichii, 8 parts of pseudo-ginseng, 2 parts of scorpion, 8 parts of earthworm, 2 parts of centipede, 8 parts of stiff silkworm, 8 parts of seaweed, 6 parts of trichosanthes kirilowii maxim, 10 parts of rhizoma cyperi, 5 parts of elecampane, 8 parts of uncaria, 8 parts of gastrodia elata, 8 parts of angelica sinensis, 8 parts of parasitic loranthus and 8 parts of caulis spatholobi.
3. The formula for treating cardiovascular and cerebrovascular diseases according to claim 1, which comprises the following components in parts by weight:
20 parts of ginseng, 60 parts of astragalus membranaceus, 15 parts of bighead atractylodes rhizome, 15 parts of poria cocos, 30 parts of cistanche, 20 parts of epimedium herb, 15 parts of prepared rehmannia root, 30 parts of tortoise plastron, 25 parts of turtle shell, 30 parts of concha haliotidis, 20 parts of selfheal, 5 parts of dragon's blood, 15 parts of rhizoma corydalis, 10 parts of frankincense, 10 parts of myrrh, 20 parts of ligusticum wallichii, 15 parts of pseudo-ginseng, 8 parts of scorpion, 15 parts of earthworm, 5 parts of centipede, 20 parts of stiff silkworm, 25 parts of seaweed, 20 parts of trichosanthes kirilowii maxim, 30 parts of rhizoma cyperi, 10 parts of elecampane, 25 parts of uncaria, 15 parts of gastrodia elata, 15 parts of angelica sinensis, 15 parts of parasitic loranthus and 30 parts of caulis spatholobi.
4. The formula for treating cardiovascular and cerebrovascular diseases according to claim 1, which comprises the following components in parts by weight:
14 parts of ginseng, 35 parts of astragalus membranaceus, 12 parts of bighead atractylodes rhizome, 12 parts of poria cocos, 22 parts of cistanche, 14 parts of epimedium herb, 11 parts of prepared rehmannia root, 20 parts of tortoise plastron, 13 parts of turtle shell, 19 parts of abalone shell, 14 parts of selfheal, 3 parts of dragon's blood, 11 parts of rhizoma corydalis, 6.5 parts of frankincense, 6.5 parts of myrrh, 14 parts of ligusticum chuanxiong hort, 11 parts of pseudo-ginseng, 5 parts of scorpion, 11 parts of earthworm, 3.5 parts of centipede, 14 parts of stiff silkworm, 11 parts of seaweed, 13 parts of snakegourd fruit, 20 parts of rhizoma cyperi, 7.5 parts of elecampane, 13 parts of uncaria, 13 parts of gastrodia elata, 12 parts of angelica sinensis, 13 parts of parasitic loranthus and 19 parts of suberect spatholobus stem.
5. A process for the preparation of a formulation for the treatment of cardiovascular and cerebrovascular diseases, wherein the formulation is a formulation according to any one of claims 1 to 4, and comprises the following steps:
respectively mixing a certain amount of ginseng, astragalus root 35, bighead atractylodes rhizome, poria cocos, cistanche deserticola, epimedium herb, prepared rehmannia root, tortoise plastron, turtle shell, abalone shell, selfheal, dragon's blood, rhizoma corydalis, frankincense, myrrh, ligusticum wallichii, pseudo-ginseng, scorpion, earthworm, centipede, stiff silkworm, seaweed, snakegourd fruit, rhizoma cyperi, costustoot, uncaria, gastrodia elata, angelica sinensis, parasitic loranthus and suberect spatholobus stem, grinding into powder with grinding equipment with certain fineness, and then mixing with honey to obtain pills.
6. The method for preparing a formulation according to claim 5, wherein the fineness of grinding of the powder is 50-100 mesh.
CN202110979054.7A 2021-08-25 2021-08-25 Formula for treating cardiovascular and cerebrovascular diseases and preparation method thereof Withdrawn CN113599463A (en)

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