CN113349830A - Gene sequencing sampling device - Google Patents
Gene sequencing sampling device Download PDFInfo
- Publication number
- CN113349830A CN113349830A CN202110577827.9A CN202110577827A CN113349830A CN 113349830 A CN113349830 A CN 113349830A CN 202110577827 A CN202110577827 A CN 202110577827A CN 113349830 A CN113349830 A CN 113349830A
- Authority
- CN
- China
- Prior art keywords
- suction nozzle
- cover plate
- nozzle shell
- fixedly connected
- pipe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000005070 sampling Methods 0.000 title claims abstract description 66
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 24
- 238000012163 sequencing technique Methods 0.000 title claims abstract description 22
- 238000009434 installation Methods 0.000 claims abstract description 4
- 238000007789 sealing Methods 0.000 claims description 48
- 230000008878 coupling Effects 0.000 claims description 2
- 238000010168 coupling process Methods 0.000 claims description 2
- 238000005859 coupling reaction Methods 0.000 claims description 2
- 210000000214 mouth Anatomy 0.000 abstract description 32
- 210000003296 saliva Anatomy 0.000 abstract description 23
- 230000000694 effects Effects 0.000 abstract description 6
- 238000005086 pumping Methods 0.000 abstract description 6
- 239000010902 straw Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 3
- 230000006399 behavior Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000002445 nipple Anatomy 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 210000000887 face Anatomy 0.000 description 1
- 238000010353 genetic engineering Methods 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a gene sequencing sampling device, wherein a suction nozzle shell is placed in the oral cavity of an infant, an installation cover plate is abutted to the outer side of the mouth of the infant, the two sides of the mouth of the infant can be approached by the infant due to habits, the suction nozzle shell is sucked, the inner wall of the oral cavity of the infant is in contact with a flexible suction pipe positioned on the outer surface of the suction nozzle shell, a negative pressure air pumping sub-component pumps air in a containing groove, saliva in the oral cavity of the infant enters the containing groove through the flexible suction pipe and is attached to a sampling swab, and a steering knob is rotated to drive a guide ring and the suction nozzle shell to axially rotate, so that the saliva on the inner wall of the whole oral cavity of the infant can be collected, and the collection effect on the inner wall of the oral cavity of the infant is enhanced.
Description
Technical Field
The invention relates to the technical field of genetic engineering, in particular to a gene sequencing and sampling device.
Background
At present, gene sequencing is a novel gene detection technology, and can analyze and determine the complete sequence of genes from blood or saliva, predict the possibility of suffering from various diseases, and ensure that the behavior characteristics and behaviors of individuals are reasonable. The gene sequencing technology can lock the individual pathological change gene and prevent and treat in advance.
The existing gene sequencing sampling device needs to stretch into the oral cavity inner wall of a sampled person, then the sampled person actively scrapes the saliva of the oral cavity inner wall, however, when the infant is sampled, the infant can not be matched with the sampling, so that the existing sampling device can not be accurately sampled by the oral cavity saliva of the sampled person, and the gene sequencing collection effect is influenced.
Disclosure of Invention
The invention aims to provide a gene sequencing sampling device, and aims to solve the technical problems that the gene sequencing sampling device in the prior art needs to stretch into the oral cavity inner wall of a person to be sampled, and then the person to be sampled actively scrapes saliva on the oral cavity inner wall, but when an infant is sampled, the existing sampling device cannot be accurately sampled by the oral cavity saliva of the person to be sampled due to the fact that the infant cannot be matched with sampling, and therefore the gene sequencing sampling effect is affected.
In order to achieve the purpose, the invention adopts a gene sequencing sampling device, which comprises an installation cover plate, a suction nozzle shell and a connecting component; the suction nozzle shell is rotatably connected with the mounting cover plate and is positioned on one side of the mounting cover plate; the connecting assembly comprises a steering seat, a guide ring, a steering knob and a sampling component, the steering seat is fixedly connected with the mounting cover plate and is positioned on the suction nozzle shell in a rotating mode and is positioned on one side, close to the suction nozzle shell, of the mounting cover plate, the guide ring is rotatably connected with the steering seat and is fixedly connected with the suction nozzle shell and is positioned on one side, close to the steering seat, of the suction nozzle shell, and the steering knob is fixedly connected with the guide ring and is rotatably connected with the mounting cover plate and is positioned on one side, far away from the suction nozzle shell, of the guide ring; the suction nozzle shell is provided with a containing groove, the containing groove is positioned in the suction nozzle shell, the opening faces one side of the mounting cover plate, the sampling component comprises a flexible suction pipe, a sampling swab, a sealing cover plate, a guide pipe and a negative pressure air exhaust sub-component, the flexible suction pipe is fixedly connected with the suction nozzle shell, positioned on one side of the suction nozzle shell, far away from the containing groove, and communicated with the containing groove, the sampling swab is detachably connected with the suction nozzle shell and positioned in the containing groove, the sealing cover plate is detachably connected with the suction nozzle shell and positioned in the containing groove and positioned on one side of the suction nozzle shell, close to the mounting cover plate, the guide pipe is fixedly connected with the sealing cover plate and penetrates through the sealing cover plate to be communicated with the containing groove, and the negative pressure air exhaust sub-component is fixedly connected with the guide pipe, and is communicated with the accommodating groove through the guide pipe.
The negative pressure air pumping sub-component comprises a one-way valve and a negative pressure pump, and the one-way valve is fixedly connected with the flow guide pipe and is positioned at one end of the flow guide pipe, which is far away from the sealing cover plate; the negative pressure pump is fixedly connected with the one-way valve and is positioned on one side of the one-way valve, which is far away from the flow guide pipe.
The negative pressure air exhaust sub-component further comprises a sealing sleeve, wherein the sealing sleeve is fixedly connected with the flow guide pipe, fixedly connected with the sealing cover plate and positioned on one side, close to the flow guide pipe, of the sealing cover plate.
The steering seat is provided with an annular groove, and the annular groove is positioned on one side of the steering seat close to the guide ring; the guide ring is provided with an annular bulge, and the annular bulge is positioned on one side of the guide ring close to the steering seat and matched with the annular groove.
The sampling component further comprises a buried pipe, the buried pipe is fixedly connected with the suction nozzle shell, is positioned on one side, close to the flexible suction pipe, of the suction nozzle shell, and is communicated with the containing groove.
The flexible suction pipe is provided with a drainage bulge, and the drainage bulge is positioned on one side, close to the buried pipe, of the flexible suction pipe and is abutted to the buried pipe.
Wherein, the sampling component still includes the sampling sucking disc, the sampling sucking disc with flexible straw fixed connection, and be located flexible straw is kept away from one side of suction nozzle casing, and with the holding tank link up.
Wherein, the sampling sucking disc has the through-hole, the through-hole is located the sampling sucking disc is close to one side of flexible straw, and with flexible straw link up.
Wherein, coupling assembling still includes the sealing washer, the sealing washer with suction nozzle casing fixed connection, and with turn to seat sliding connection, and be located the suction nozzle casing is close to turn to one side of seat.
According to the gene sequencing sampling device, the suction nozzle shell is placed in the oral cavity of an infant, the mounting cover plate is abutted to the outer side of the mouth of the infant, the two sides of the mouth of the infant can be approached by the infant due to habits, the suction nozzle shell is sucked, the inner wall of the oral cavity of the infant is in contact with the flexible suction pipe located on the outer surface of the suction nozzle shell, the negative pressure air pumping sub-component pumps air in the accommodating groove, saliva in the oral cavity of the infant enters the accommodating groove through the flexible suction pipe and is attached to the sampling swab, the steering knob is rotated to drive the guide ring and the suction nozzle shell to axially rotate, the saliva on the inner wall of the whole oral cavity of the infant can be collected, and the collection effect on the inner wall of the oral cavity of the infant is enhanced.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic view of the structure of the sampling member of the present invention.
Fig. 2 is a schematic view of the connection structure of the suction nozzle housing and the sampling suction cup of the present invention.
Fig. 3 is a schematic view of the construction of the connection assembly of the present invention.
FIG. 4 is a structural exploded view of the deflector shoe and guide ring of the present invention.
FIG. 5 is a schematic view of the connecting structure of the burying pipe and using the suction cup of the present invention.
In the figure: 1-mounting cover plate, 2-suction nozzle shell, 3-connecting component, 21-accommodating groove, 31-steering seat, 32-guide ring, 33-steering knob, 34-sampling component, 35-sealing ring, 100-gene sequencing sampling device, 311-annular groove, 321-annular bulge, 341-flexible sucker, 342-sampling swab, 343-sealing cover plate, 344-draft tube, 345-negative pressure air sucker component, 346-embedded tube, 347-sampling sucker, 3411-drainage bulge, 3451-one-way valve, 3452-negative pressure pump, 3453-sealing sleeve and 3471-through hole.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the invention and are not to be construed as limiting the invention.
In the description of the present invention, it is to be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships illustrated in the drawings, and are used merely for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, are not to be construed as limiting the present invention. Further, in the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
Referring to fig. 1 to 5, the present invention provides a gene sequencing sampling device 100, which includes an installation cover plate 1, a nozzle housing 2 and a connection assembly 3; the suction nozzle shell 2 is rotatably connected with the mounting cover plate 1 and is positioned on one side of the mounting cover plate 1; the connecting assembly 3 comprises a steering seat 31, a guide ring 32, a steering knob 33 and a sampling member 34, the steering seat 31 is fixedly connected with the mounting cover plate 1, is positioned on the suction nozzle shell 2 in a rotating manner, and is positioned on one side of the mounting cover plate 1 close to the suction nozzle shell 2, the guide ring 32 is rotatably connected with the steering seat 31, is fixedly connected with the suction nozzle shell 2, and is positioned on one side of the suction nozzle shell 2 close to the steering seat 31, the steering knob 33 is fixedly connected with the guide ring 32, is rotatably connected with the mounting cover plate 1, and is positioned on one side of the guide ring 32 away from the suction nozzle shell 2; the suction nozzle housing 2 has a receiving groove 21, the receiving groove 21 is located inside the suction nozzle housing 2 and opens toward one side of the mounting cover plate 1, the sampling member 34 includes a flexible suction tube 341, a sampling swab 342, a sealing cover plate 343, a flow guide tube 344 and a negative pressure suction sub-member 345, the flexible suction tube 341 is fixedly connected with the suction nozzle housing 2 and located on one side of the suction nozzle housing 2 away from the receiving groove 21 and is communicated with the receiving groove 21, the sampling swab 342 is detachably connected with the suction nozzle housing 2 and is located in the receiving groove 21, the sealing cover plate 343 is detachably connected with the suction nozzle housing 2 and is located in the receiving groove 21 and is located on one side of the suction nozzle housing 2 close to the mounting cover plate 1, and the flow guide tube 344 is fixedly connected with the sealing cover plate 343 and penetrates through the sealing cover plate 343, and the negative pressure pumping sub-member 345 is fixedly connected to the guide pipe 344, and is connected to the accommodating groove 21 through the guide pipe 344.
In this embodiment, the mounting cover plate 1 is a mounting seat of the nozzle housing 2, the mounting cover plate 1 is a rounded rectangle, and can prevent an infant from swallowing the nozzle housing 2 during a sucking process, a hole is formed in the center of the mounting cover plate 1, the steering seat 31 is bonded and fixed in the hole of the mounting cover plate 1, and the steering seat 31 is a hollow annular seat and surrounds the mounting cover plate 1 for a circle of the hole; the guide ring 32 is rotatably mounted on the inner side wall of the steering seat 31, the guide ring 32 is a circular ring with a diameter smaller than that of the steering seat 31, and is rotatably mounted on the inner side wall of the steering seat 31; because the suction nozzle shell 2 is made of a conventional nipple material, an infant can consider that the suction nozzle shell 2 is a nipple, the opening end part of the suction nozzle shell 2 is fixed with the guide ring 32 through a bracket and a screw thread, so that the accommodating groove 21 of the suction nozzle shell 2 is communicated with the hollow interior of the guide ring 32, and the rotation of the guide ring 32 drives the suction nozzle shell 2 to axially rotate, so that the suction nozzle shell 2 is rotatably mounted on the mounting cover plate 1; the transverse section of the suction nozzle shell 2 is elliptical, a large number of flexible suction pipes 341 are mounted on the side surface of the suction nozzle shell 2, the flexible suction pipes 341 transversely penetrate through the side wall of the suction nozzle shell 2 and extend into the suction nozzle shell 2, the flexible suction pipes 341 are made of silica gel, are non-toxic and have good flexibility, the side wall of the oral cavity of an infant and the tongue do not feel painful when being in contact with the flexible suction pipes 341, and the suction head of the flexible suction pipes 341 is in contact with the side wall of the oral cavity of the infant, so that the side wall of the oral cavity of the infant can be tightly attached to the top of the flexible suction pipes 341 in the sucking process; the inside of the mouthpiece housing 2 is filled with the sampling swab 342, the sampling swab 342 is a conventional saliva collecting swab, and can collect saliva flowing into the inside of the mouthpiece housing 2 through the flexible pipette 341, because the entrance efficiency of saliva from the flexible pipette 341 is low, the flow guide tube 344 can be mounted on the sealing cover plate 343, the flow guide tube 344 penetrates through the sealing cover plate 343 and is communicated with the inside of the accommodating groove 21, the negative pressure air suction member can suck air in the accommodating groove 21 through the flow guide tube 344, so that the air pressure in the accommodating groove 21 is lower than the external atmospheric pressure, and the saliva can rapidly enter the accommodating groove 21 and contact with the sampling swab 342; thus, the suction nozzle housing 2 is placed in the oral cavity of an infant, the mounting cover plate 1 abuts against the outer side of the mouth of the infant, the infant can approach the two sides of the mouth due to habit to suck the suction nozzle housing 2, at this time, the inner wall of the oral cavity of the infant is in contact with the flexible suction pipe 341 on the outer surface of the suction nozzle housing 2, the negative pressure air extractor component 345 extracts air in the accommodating groove 21, saliva in the oral cavity of the infant enters the accommodating groove 21 through the flexible suction pipe 341 and is attached to the sampling swab 342, the steering knob 33 is rotated to drive the guide ring 32 and the suction nozzle housing 2 to axially rotate, the saliva on the inner wall of the whole oral cavity of the infant can be collected, and the collection effect on the inner wall of the oral cavity of the infant is enhanced.
Further, referring to fig. 1 and fig. 3, the negative pressure pumping sub-component 345 includes a one-way valve 3451 and a negative pressure pump 3452, the one-way valve 3451 is fixedly connected to the flow guide pipe 344 and is located at an end of the flow guide pipe 344 away from the sealing cover 343; the negative pressure pump 3452 is fixedly connected to the check valve 3451 and is located on a side of the check valve 3451 away from the flow guide pipe 344.
In this embodiment, the type of the check valve 3451 is CVB0, the check valve 3451 is a micro check valve 3451, the negative pressure pump 3452 is a combination device of an air suction cylinder, an air suction piston and an air suction pull rod, the air suction cylinder of the negative pressure pump 3452 is connected and communicated with the check valve 3451 through a sealing ring 35, and the air in the accommodating tank 21 is guided out through the flow guide pipe 344 by the negative pressure pump 3452, so that saliva can rapidly enter the accommodating tank 21.
Further, referring to fig. 3, the negative pressure pumping sub-component 345 further includes a sealing sleeve 3453, and the sealing sleeve 3453 is fixedly connected to the flow guide pipe 344, fixedly connected to the sealing cover 343, and located on a side of the sealing cover 343 close to the flow guide pipe 344.
In this embodiment, the sealing sleeve 3453 is made of rubber, is sleeved on the outer side of the flow guide pipe 344, and is in contact with and fixed to the sealing cover plate 343, and the sealing sleeve 3453 seals a gap between the flow guide pipe 344 and the sealing cover plate 343, so that the gap between the sealing cover plate 343 and the flow guide pipe 344 is sealed, and the sealing performance between the flow guide pipe 344 and the sealing cover plate 343 is better.
Further, referring to fig. 4, the steering seat 31 has an annular groove 311, and the annular groove 311 is located on a side of the steering seat 31 close to the guide ring 32; the guide ring 32 has an annular protrusion 321, and the annular protrusion 321 is located on one side of the guide ring 32 close to the steering seat 31 and is matched with the annular groove 311.
In this embodiment, the annular groove is formed in the inner side wall of the steering seat 31, the annular groove 311 is a T-shaped groove, and the outer side surface of the guide ring 32 is provided with a T-shaped protrusion, so that the connection effect between the guide ring 32 and the steering seat 31 is better, and the guide ring 32 can only axially rotate on the steering seat 31.
Further, referring to fig. 2, the sampling member 34 further includes a buried pipe 346, and the buried pipe 346 is fixedly connected to the nozzle housing 2, is located at a side of the nozzle housing 2 close to the flexible suction pipe 341, and is communicated with the accommodating groove 21.
Further, referring to fig. 5, the flexible suction pipe 341 has a drainage protrusion 3411, and the drainage protrusion 3411 is located on a side of the flexible suction pipe 341 close to the burying pipe 346 and abuts against the burying pipe 346.
In this embodiment, the embedded pipes 346 penetrate the nozzle housing 2, and are provided in plural numbers, and are respectively close to the flexible suction pipes 341, the embedded pipes 346 protrude from the nozzle housing 2 at a height lower than the flexible suction pipes 341, so that the flexible suction pipes 341 absorb saliva in the oral cavity first, and the unabsorbed part flows into the embedded pipes 346 through the drainage protrusions 3411, and the drainage protrusions 3411 are arc-shaped protrusions and made of a silicone material, and can drain the saliva to the nozzle position of the embedded pipes 346 and flow into the receiving grooves 21 of the nozzle housing 2 through the embedded pipes 346, so that more saliva can be collected.
Further, referring to fig. 1 and 2, the sampling member 34 further includes a sampling suction cup 347, and the sampling suction cup 347 is fixedly connected to the flexible suction tube 341, is located on a side of the flexible suction tube 341 away from the nozzle housing 2, and is communicated with the accommodating groove 21.
In this embodiment, the sampling suction cups 347 have a disk shape, and a plurality of sampling suction cups 347 are provided, each of the sampling suction cups 347 is bonded and fixed to the free end portion of the flexible suction tube 341, and the mouth of each of the sampling suction cups 347 has a circular shape, so that the area for absorbing saliva is larger, and more saliva can be collected,
further, referring to fig. 1 and 2, the sampling sucker 347 has a through hole 3471, and the through hole 3471 is located on one side of the sampling sucker 347 close to the flexible suction tube 341 and is communicated with the flexible suction tube 341.
In this embodiment, the through hole 3471 is formed in the sampling suction cup 347, and the through hole 3471 axially penetrates through the center of the sampling suction cup 347, so that the sampling suction cup 347 and the flexible suction tube 341 penetrate through each other, and saliva flows into the flexible suction tube 341 from the through hole 3471 and then flows into the accommodating groove 21.
Further, referring to fig. 3, the connection assembly 3 further includes a sealing ring 35, and the sealing ring 35 is fixedly connected to the nozzle housing 2, slidably connected to the steering seat 31, and located on one side of the nozzle housing 2 close to the steering seat 31.
In this embodiment, sealing washer 35 cover is established the outside of suction nozzle casing 2, it is right turn to seat 31 and then the cover is established, sealing washer 35 is the rubber material, has good wearability, and right suction nozzle casing 2 with turn to the gap between the seat 31 and seal, avoid the saliva outflow.
While the invention has been described with reference to a preferred embodiment, it will be understood by those skilled in the art that various changes in form and detail may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (7)
1. A gene sequencing sampling device is characterized by comprising an installation cover plate, a suction nozzle shell and a connecting component;
the suction nozzle shell is rotatably connected with the mounting cover plate and is positioned on one side of the mounting cover plate;
the connecting assembly comprises a steering seat, a guide ring, a steering knob and a sampling component, the steering seat is fixedly connected with the mounting cover plate and is positioned on the suction nozzle shell in a rotating mode and is positioned on one side, close to the suction nozzle shell, of the mounting cover plate, the guide ring is rotatably connected with the steering seat and is fixedly connected with the suction nozzle shell and is positioned on one side, close to the steering seat, of the suction nozzle shell, and the steering knob is fixedly connected with the guide ring and is rotatably connected with the mounting cover plate and is positioned on one side, far away from the suction nozzle shell, of the guide ring;
the suction nozzle shell is provided with a containing groove, the containing groove is positioned in the suction nozzle shell, the opening faces one side of the mounting cover plate, the sampling component comprises a flexible suction pipe, a sampling swab, a sealing cover plate, a guide pipe and a negative pressure air exhaust sub-component, the flexible suction pipe is fixedly connected with the suction nozzle shell, positioned on one side of the suction nozzle shell, far away from the containing groove, and communicated with the containing groove, the sampling swab is detachably connected with the suction nozzle shell and positioned in the containing groove, the sealing cover plate is detachably connected with the suction nozzle shell and positioned in the containing groove and positioned on one side of the suction nozzle shell, close to the mounting cover plate, the guide pipe is fixedly connected with the sealing cover plate and penetrates through the sealing cover plate to be communicated with the containing groove, and the negative pressure air exhaust sub-component is fixedly connected with the guide pipe, and is communicated with the accommodating groove through the guide pipe.
2. The gene sequencing sampling device of claim 1,
the negative pressure air extractor component comprises a one-way valve and a negative pressure pump, and the one-way valve is fixedly connected with the flow guide pipe and is positioned at one end of the flow guide pipe, which is far away from the sealing cover plate; the negative pressure pump is fixedly connected with the one-way valve and is positioned on one side of the one-way valve, which is far away from the flow guide pipe.
3. The gene sequencing sampling device of claim 1,
the negative pressure air exhaust sub-component further comprises a sealing sleeve, wherein the sealing sleeve is fixedly connected with the flow guide pipe, fixedly connected with the sealing cover plate and positioned on one side, close to the flow guide pipe, of the sealing cover plate.
4. The gene sequencing sampling device of claim 1,
the steering seat is provided with an annular groove which is positioned on one side of the steering seat close to the guide ring; the guide ring is provided with an annular bulge, and the annular bulge is positioned on one side of the guide ring close to the steering seat and matched with the annular groove.
5. The gene sequencing sampling device of claim 1,
the sampling component further comprises a buried pipe, the buried pipe is fixedly connected with the suction nozzle shell, is positioned on one side, close to the flexible suction pipe, of the suction nozzle shell, and is communicated with the containing groove.
6. The gene sequencing sampling device of claim 5,
the flexible suction pipe is provided with a drainage bulge, and the drainage bulge is positioned on one side, close to the buried pipe, of the flexible suction pipe and is abutted to the buried pipe.
7. The gene sequencing sampling device of claim 1,
coupling assembling still includes the sealing washer, the sealing washer with suction nozzle casing fixed connection, and with turn to seat sliding connection, and be located the suction nozzle casing is close to turn to one side of seat.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110577827.9A CN113349830B (en) | 2021-05-26 | 2021-05-26 | Gene sequencing sampling device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110577827.9A CN113349830B (en) | 2021-05-26 | 2021-05-26 | Gene sequencing sampling device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113349830A true CN113349830A (en) | 2021-09-07 |
| CN113349830B CN113349830B (en) | 2022-05-06 |
Family
ID=77527616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110577827.9A Active CN113349830B (en) | 2021-05-26 | 2021-05-26 | Gene sequencing sampling device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113349830B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114736783A (en) * | 2022-06-10 | 2022-07-12 | 深圳市华晨阳科技有限公司 | Sample sampler for detecting infant mucosa gene |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040022687A1 (en) * | 2002-07-31 | 2004-02-05 | Thomas Wuske | Device and process for collecting and releasing saliva |
| EP1397997A1 (en) * | 2002-09-04 | 2004-03-17 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Detection device |
| US20120021375A1 (en) * | 2010-07-26 | 2012-01-26 | Curt Binner | Devices and methods for collecting and analyzing fluid samples from the oral cavity |
| CN204484173U (en) * | 2015-03-12 | 2015-07-22 | 天津市南开医院 | Baby's spittle collector |
| CN205607690U (en) * | 2016-04-25 | 2016-09-28 | 泰济生健康管理有限公司 | Infant's saliva sample collection device |
| CN108309358A (en) * | 2018-01-31 | 2018-07-24 | 上海交通大学医学院附属上海儿童医学中心 | Nipple type detection device |
| CN211704698U (en) * | 2020-01-17 | 2020-10-20 | 南京市中心医院 | Oral saliva collector |
| WO2020260583A1 (en) * | 2019-06-28 | 2020-12-30 | Universiteit Gent | Sampling device for biological specimen |
-
2021
- 2021-05-26 CN CN202110577827.9A patent/CN113349830B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040022687A1 (en) * | 2002-07-31 | 2004-02-05 | Thomas Wuske | Device and process for collecting and releasing saliva |
| EP1397997A1 (en) * | 2002-09-04 | 2004-03-17 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Detection device |
| US20120021375A1 (en) * | 2010-07-26 | 2012-01-26 | Curt Binner | Devices and methods for collecting and analyzing fluid samples from the oral cavity |
| CN204484173U (en) * | 2015-03-12 | 2015-07-22 | 天津市南开医院 | Baby's spittle collector |
| CN205607690U (en) * | 2016-04-25 | 2016-09-28 | 泰济生健康管理有限公司 | Infant's saliva sample collection device |
| CN108309358A (en) * | 2018-01-31 | 2018-07-24 | 上海交通大学医学院附属上海儿童医学中心 | Nipple type detection device |
| WO2020260583A1 (en) * | 2019-06-28 | 2020-12-30 | Universiteit Gent | Sampling device for biological specimen |
| CN211704698U (en) * | 2020-01-17 | 2020-10-20 | 南京市中心医院 | Oral saliva collector |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114736783A (en) * | 2022-06-10 | 2022-07-12 | 深圳市华晨阳科技有限公司 | Sample sampler for detecting infant mucosa gene |
| CN114736783B (en) * | 2022-06-10 | 2022-08-16 | 深圳市华晨阳科技有限公司 | Sample sampler for detecting infant mucosa gene |
Also Published As
| Publication number | Publication date |
|---|---|
| CN113349830B (en) | 2022-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102421465B (en) | Drainage tube apparatus and coupling unit | |
| CN113349830B (en) | Gene sequencing sampling device | |
| CN211096367U (en) | Drainage decompression sleeve device for intestinal obstruction | |
| CN221690618U (en) | Suction pipe cup cover | |
| CN210542600U (en) | Intubation patient saliva drainage collection device | |
| CN213156039U (en) | Sampling and collecting device for patients bitten by venomous snakes | |
| CN111657963A (en) | Blood sample preparation device for blood sampling management system | |
| CN215840770U (en) | Brassiere and electric breast pump with reverse flow valve | |
| CN219878223U (en) | Flowing thrombus collecting device for collecting blood vessel | |
| CN220833065U (en) | Nasal secretion collection system | |
| CN219681296U (en) | Anti-overflow breast collector | |
| CN215424798U (en) | Gastric juice extraction element is used in gastroscope room inspection | |
| CN217040878U (en) | Stomach tube drainage external member | |
| CN213491202U (en) | Portable self-stopping dropping funnel | |
| CN207613844U (en) | Sting device is arranged outside internal hydrops | |
| CN219941534U (en) | Disposable nasal cavity suction tube | |
| CN219462051U (en) | Anti-overflow phlegm collecting cup | |
| CN217697445U (en) | Electric breast pump | |
| CN211512814U (en) | Ascites continuous aspirator | |
| CN217245733U (en) | Suction structure of disposable endoscope and disposable endoscope | |
| CN209529372U (en) | Oral cavity Simple-structure flusher | |
| CN214761212U (en) | Saliva collector with sealed storage performance | |
| CN217245959U (en) | Anti-pollution structure of micro pump syringe and micro pump | |
| CN221555727U (en) | Two-cavity polyp filter | |
| CN221655355U (en) | Shield assembly and breast pump |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |