CN113230511A - Target control drug administration device - Google Patents

Target control drug administration device Download PDF

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Publication number
CN113230511A
CN113230511A CN202110572558.7A CN202110572558A CN113230511A CN 113230511 A CN113230511 A CN 113230511A CN 202110572558 A CN202110572558 A CN 202110572558A CN 113230511 A CN113230511 A CN 113230511A
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China
Prior art keywords
anesthesia machine
air
depth monitoring
drug delivery
delivery device
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Pending
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CN202110572558.7A
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Chinese (zh)
Inventor
刘馨
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West China Hospital of Sichuan University
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West China Hospital of Sichuan University
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Priority to CN202110572558.7A priority Critical patent/CN113230511A/en
Publication of CN113230511A publication Critical patent/CN113230511A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/01Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes specially adapted for anaesthetising
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4821Determining level or depth of anaesthesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0051Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes with alarm devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/18Vaporising devices for anaesthetic preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/18General characteristics of the apparatus with alarm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/08Other bio-electrical signals
    • A61M2230/10Electroencephalographic signals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention discloses a target control drug delivery device which comprises a workbench, a conversion analysis module and a depth monitoring box, wherein the bottom end of the workbench is fixedly connected with a lifter, the bottom end of the lifter is fixedly connected with a base, the top end of the workbench is provided with an anesthesia machine, one side of the anesthesia machine is rotatably connected with a breathing loop, the top end of the anesthesia machine is rotatably connected with a first air/oxygen inlet, and one side of the first air/oxygen inlet is connected with a first regulating valve. According to the invention, through the arrangement of the conversion analysis module, the conversion analysis module analyzes data transmitted by electroencephalogram information, the anesthesia depth of a patient is judged through electroencephalogram indexes, through the arrangement of the regulation and control module, the regulation and control module can regulate the work of the anesthesia machine according to the current concentration of anesthetic gas, and through changing the dosage of the evaporation tank, the concentration of anesthetic is regulated.

Description

Target control drug administration device
Technical Field
The invention relates to the technical field of target-controlled drug delivery, in particular to a target-controlled drug delivery device.
Background
The safe use of the anesthetic has important significance for protecting the perioperative life safety of a patient and meeting the operation comfort level, the too low dosage cannot meet the painless requirement of the patient in the operation process, meanwhile, the strong stress can also cause the organism to have various complications to influence the life quality of the patient, the too high dosage concentration can excessively inhibit the central nervous function of the patient, even can cause the malignant adverse event of the cardiovascular and cerebrovascular, and influences the life safety of the patient.
At present, the existing target control drug delivery device can only reflect the concentration of an effect chamber and the drug delivery concentration of intravenous anesthetic drugs, cannot reflect the activity degree of electrical activity of a central nervous system, cannot timely adjust the dosage of the anesthetic drugs while monitoring the depth of anesthesia, and is not mature in the target control drug delivery technology aiming at inhalation anesthetic drugs. We have therefore developed an improved target controlled drug delivery device.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention provides a target control drug delivery device.
In order to solve the technical problems, the invention provides the following technical scheme:
the invention relates to a target control drug delivery device, which comprises a workbench, a conversion analysis module and a depth monitoring box, wherein the bottom end of the workbench is fixedly connected with a lifter, the bottom end of the lifter is fixedly connected with a base, the top end of the workbench is provided with an anesthesia machine, one side of the anesthesia machine is rotatably connected with a breathing loop, the breathing loop is connected with a breathing mask or an artificial airway, the top end of the anesthesia machine is rotatably connected with a first air/oxygen inlet, one side of the first air/oxygen inlet is connected with a first regulating valve, one side of the first air/oxygen inlet is rotatably connected with a second air/oxygen inlet, one side of the second air/oxygen inlet is provided with a second regulating valve, one side of the anesthesia machine is fixedly provided with the depth monitoring box, one side of the depth monitoring box is fixedly provided with an alarm lamp, the inner cavity of the anesthesia machine is provided with an evaporating pot, one side of the anesthesia machine is rotatably connected with a guide pipe, and one side of the guide pipe is provided with a waste gas outlet.
As a preferred technical scheme of the invention, one side of the depth monitoring box is fixedly connected with an electrode patch, the alarm lamp is connected with the depth monitoring box through a bolt, and one side of the depth monitoring box is rotatably connected with a sampling pipe.
As a preferred technical scheme of the invention, a depth monitoring module is fixedly arranged in an inner cavity of the depth monitoring box, one side of the depth monitoring module is connected with electroencephalogram information, and one side of the electroencephalogram information is provided with a conversion analysis module.
As a preferred technical scheme of the invention, one side of the conversion analysis module is connected with a regulation and control module, and one side of the regulation and control module is connected with an anesthesia machine.
As a preferred technical scheme of the invention, one side of the first air/oxygen inlet is connected with a first air inlet pipe, the first regulating valve is connected with the first air inlet pipe in a clamping manner, one side of the second air/oxygen inlet is connected with a second air inlet pipe, the second regulating valve is connected with the second air inlet pipe in a clamping manner, and the bottom ends of the first air inlet pipe and the second air inlet pipe are both connected with an inner cavity of the anesthesia machine.
As a preferred technical scheme of the invention, the bottom end of the evaporation tank is fixedly connected with an inner cavity of the anesthesia machine, the evaporation tank is electrically connected with a storage battery at the bottom end of the workbench, and the top end of the evaporation tank is provided with a steam outlet.
As a preferable technical scheme of the invention, one end of the conduit is connected with an inner cavity of the anesthesia machine, one side of the conduit is rotatably connected with a breathing mask, the inner cavity of the conduit is provided with a shunt port, and the shunt port is connected with the waste gas outlet.
The invention has the beneficial effects that: according to the target control drug delivery device, through the arrangement of the electrode patch and the alarm lamp, when the electrode patch is attached to the head of a patient, the depth monitoring box can display brain wave data of the patient, reflect the anesthesia depth of the patient, and the alarm lamp flickers and rings to give an alarm prompt when the depth is abnormal; a side hole close to the end of the artificial airway/oxygen mask in the breathing loop can be connected with a pipeline to detect the concentration of the anesthetic inhaled by the patient in real time; analyzing data transmitted by the electroencephalogram information by a conversion analysis module, judging whether the concentration of the inhaled anesthetic in the body of the patient is too high or too low when the electroencephalogram index is abnormal, and formulating the concentration of the target anesthetic; the evaporation rate of the evaporation tank is regulated and controlled by adjusting a rotary button at the top of the evaporation tank, so that the concentration of the inhalation anesthetic is changed. On the other hand, when the anesthesia depth is abnormal, the alarm lamp rings to prompt the user, and the clinical anesthesia doctor can also manually adjust the concentration of the inhalant according to the clinical experience of the clinical anesthesia doctor directly based on the displayed electroencephalogram index, so that the device is used for supplementing and perfecting automatic adjustment.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention.
In the drawings:
FIG. 1 is a schematic perspective view of a target-controlled drug delivery device according to the present invention;
FIG. 2 is a schematic perspective view of a target-controlled drug delivery device according to the present invention;
FIG. 3 is a system diagram of a target-controlled drug delivery device of the present invention.
In the figure: 1. a base; 2. a conduit; 3. an elevator; 4. an exhaust gas outlet; 5. a work table; 6. an anesthesia machine; 7. a first air/oxygen inlet; 8. a second air/oxygen inlet; 9. a depth monitoring box; 10. electrode pasting; 11. respiratory mask/artificial airway; 12. an alarm light; 13. a first regulating valve; 14. a second regulating valve; 15. an evaporator tank; 16. a depth monitoring module; 17. electroencephalogram information; 18. a conversion analysis module; 19. and a regulation module.
Detailed Description
The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are described herein for the purpose of illustration and explanation and not limitation.
Example (b): as shown in fig. 1, 2 and 3, the target-controlled drug delivery device of the present invention comprises a workbench 5, a conversion analysis module 18 and a depth monitoring box 9, wherein the bottom end of the workbench 5 is fixedly connected with a lifter 3, the bottom end of the lifter 3 is fixedly connected with a base 1, the top end of the workbench 5 is provided with an anesthesia machine 6, one side of the anesthesia machine 6 is rotatably connected with a breathing circuit, the breathing circuit is connected with a breathing mask or an artificial airway 11, the top end of the anesthesia machine 6 is rotatably connected with a first air/oxygen inlet 7, one side of the first air/oxygen inlet 7 is connected with a first regulating valve 13, one side of the first air/oxygen inlet 7 is rotatably connected with a second air/oxygen inlet 8, one side of the second air/oxygen inlet 8 is provided with a second regulating valve 14, one side of the anesthesia machine 6 is fixedly provided with the depth monitoring box 9, one side of the depth monitoring box 9 is fixedly provided with an alarm lamp 12, an evaporating pot 15 is arranged in the inner cavity of the anesthesia machine 6, a guide pipe 2 is rotatably connected to one side of the anesthesia machine 6, and a waste gas outlet 4 is formed in one side of the guide pipe 2.
Wherein, one side fixedly connected with electrode paster 10 of degree of depth monitoring case 9, alarm lamp 12 and degree of depth monitoring case 9 bolted connection, one side of degree of depth monitoring case 9 is rotated and is connected with the sampling pipe, through electrode paster 10 and alarm lamp 12's setting, when pasting patient's head with electrode paster 10, degree of depth monitoring case 9 can show patient's brain wave data, be convenient for conversion module and staff judge patient's anesthesia degree of depth according to brain wave data, and when patient brain wave index is unusual, alarm lamp 12 rings suggestion user of using personnel.
Wherein, the fixed depth monitoring module 16 that is provided with of inner chamber of depth monitoring case 9, one side of depth monitoring module 16 is connected with brain electrical information 17, and one side of brain electrical information 17 is provided with conversion analysis module 18, and through the setting of conversion analysis module 18, conversion analysis module 18 carries out the analysis with the data of brain electrical information 17 transmission, formulates the concentration of target narcotic through patient's brain electrical index and internal narcotic concentration.
Wherein, one side of conversion analysis module 18 is connected with regulation and control module 19, and one side of regulation and control module 19 is connected with anesthesia machine 6, and through regulation and control module 19's setting, the machine can be according to the work that anesthesia machine 6 was adjusted through regulation and control module 19 to the concentration of anesthetic gas now.
Wherein, one side of first air/oxygen import 7 is connected with first intake pipe, first governing valve 13 is connected with first intake pipe block, one side of second air/oxygen import 8 is connected with the second intake pipe, second governing valve 14 is connected with second intake pipe block, the bottom of first intake pipe and second intake pipe all links to each other with the inner chamber of anesthesia machine 6, through the setting of first governing valve 13 with second governing valve 14, through the use dose that changes the evaporating pot, so that the concentration of direct regulation narcotic.
Wherein, the bottom of evaporating pot 15 and the inner chamber fixed connection of anesthesia machine 6, the battery electric connection of evaporating pot 15 and 5 bottoms of workstation, the steam outlet has been seted up on the top of evaporating pot 15, through the setting of evaporating pot 15, can carry out artificial regulation and control evaporating pot 15's evaporation rate through the rotary button in the 15 outsides of evaporating pot, improved the convenience of device.
Wherein, the one end of pipe 2 links to each other with anesthesia machine 6's inner chamber, and one side of pipe 2 is rotated and is connected with respirator/artificial air flue 11, and the inner chamber of pipe 2 is provided with the diffluence pass, and the diffluence pass links to each other with exhaust outlet 4, through respirator/artificial air flue 11's setting, can be through the gas of patient exhalation, the side detects the concentration of narcotic, and is convenient for input narcotic to the patient, has improved the practicality of device.
When the device works, when the electrode patch 10 is attached to the head of a patient, the depth monitoring box 9 can display electroencephalogram data of the patient, the conversion module and workers can conveniently judge the anesthesia depth of the patient according to the electroencephalogram data, when the electroencephalogram index of the patient is abnormal, the alarm lamp 12 rings to prompt the users, the conversion analysis module 18 analyzes data transmitted by electroencephalogram information 17, one side of the catheter 2 is rotatably connected with a breathing mask/artificial airway 11, the inner cavity of the catheter 2 is provided with a shunt port, the use concentration of the current anesthetic can be detected through gas exhaled by the patient, the analysis module formulates the concentration of the target anesthetic through the electroencephalogram index of the patient and the concentration of the anesthetic in the body, the device can adjust the work of the anesthetic machine 6 through the adjusting and controlling module 19 according to the concentration of the current anesthetic gas, the use dosage of the evaporation tank is changed, and the concentration of the anesthetic is directly adjusted, the bottom end of the evaporation tank 15 is fixedly connected with the inner cavity of the anesthesia machine 6, and the evaporation rate of the evaporation tank 15 can be artificially regulated and controlled through a rotary button on the outer side of the evaporation tank 15 to supplement the regulation and control of the device.
Finally, it should be noted that: in the description of the present invention, it should be noted that the terms "vertical", "upper", "lower", "horizontal", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention.
In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (7)

1. A target control drug delivery device comprises a workbench (5), a conversion analysis module (18) and a depth monitoring box (9), and is characterized in that the bottom end of the workbench (5) is fixedly connected with a lifter (3), the bottom end of the lifter (3) is fixedly connected with a base (1), the top end of the workbench (5) is provided with an anesthesia machine (6), one side of the anesthesia machine (6) is rotatably connected with a breathing circuit, the breathing circuit is connected with a breathing mask (11) or an artificial airway, the top end of the anesthesia machine (6) is rotatably connected with a first air/oxygen inlet (7), one side of the first air/oxygen inlet (7) is connected with a first regulating valve (13), one side of the first air/oxygen inlet (7) is rotatably connected with a second air/oxygen inlet (8), one side of the second air/oxygen inlet (8) is provided with a second regulating valve (14), the fixed degree of depth monitoring case (9) that is provided with in one side of anesthesia machine (6), the fixed warning light (12) that is provided with in one side of degree of depth monitoring case (9), the inner chamber of anesthesia machine (6) is provided with evaporating pot (15), one side of anesthesia machine (6) is rotated and is connected with pipe (2), exhaust outlet (4) have been seted up to one side of pipe (2).
2. The target controlled drug delivery device as claimed in claim 1, wherein an electrode patch (10) is fixedly connected to one side of the depth monitoring box (9), the alarm lamp (12) is bolted to the depth monitoring box (9), and a sampling tube is rotatably connected to one side of the depth monitoring box (9).
3. The target controlled drug delivery device according to claim 1, characterized in that a depth monitoring module (16) is fixedly arranged in the inner cavity of the depth monitoring box (9), one side of the depth monitoring module (16) is connected with electroencephalogram information (17), and one side of the electroencephalogram information (17) is provided with a conversion analysis module (18).
4. The target controlled drug delivery device according to claim 1, characterized in that a control module (19) is connected to one side of the conversion and analysis module (18), and an anesthesia machine (6) is connected to one side of the control module (19).
5. The target-controlled drug delivery device according to claim 1, wherein a first air inlet pipe is connected to one side of the first air/oxygen inlet (7), the first regulating valve (13) is connected with the first air inlet pipe in a clamping manner, a second air inlet pipe is connected to one side of the second air/oxygen inlet (8), the second regulating valve (14) is connected with the second air inlet pipe in a clamping manner, and the bottom ends of the first air inlet pipe and the second air inlet pipe are connected with the inner cavity of the anesthesia machine (6).
6. The target controlled drug delivery device according to claim 1, wherein the bottom end of the evaporation tank (15) is fixedly connected with the inner cavity of the anesthesia machine (6), the evaporation tank (15) is electrically connected with a storage battery at the bottom end of the workbench (5), and the top end of the evaporation tank (15) is provided with a steam outlet.
7. The target controlled drug delivery device according to claim 1, characterized in that one end of the catheter (2) is connected with the inner cavity of the anesthesia machine (6), one side of the catheter (2) is rotatably connected with a breathing loop (11), the inner cavity of the catheter (2) is provided with a branch port, and the branch port is connected with the waste gas outlet (4).
CN202110572558.7A 2021-05-25 2021-05-25 Target control drug administration device Pending CN113230511A (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020173729A1 (en) * 2001-05-18 2002-11-21 Hanna Viertio-Oja Closed loop drug administration method and apparatus using eeg complexity for control purposes
WO2008059289A2 (en) * 2006-11-13 2008-05-22 Alan Hector Wenman Depth of anaesthesia
CN104888327A (en) * 2015-05-27 2015-09-09 王莹 Rapid emergency anesthesia machine for ICU (intensive care unit) department
CN105233383A (en) * 2015-09-12 2016-01-13 张萍 Foldable anesthesia machine with automatic warning device
CN106955403A (en) * 2017-03-15 2017-07-18 中国人民解放军第三军医大学第二附属医院 A kind of closed loop inhalation anesthesia control system
CN108904941A (en) * 2018-06-12 2018-11-30 深圳市人民医院 A kind of intelligent operation anesthesia management system
CN211213107U (en) * 2019-11-23 2020-08-11 成都市龙泉驿区第一人民医院 Anesthesia depth monitoring device for anesthesia
CN112354055A (en) * 2020-11-03 2021-02-12 遵义医科大学 Inhalation type continuous anesthesia system with adjustable dosage and method

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020173729A1 (en) * 2001-05-18 2002-11-21 Hanna Viertio-Oja Closed loop drug administration method and apparatus using eeg complexity for control purposes
WO2008059289A2 (en) * 2006-11-13 2008-05-22 Alan Hector Wenman Depth of anaesthesia
CN104888327A (en) * 2015-05-27 2015-09-09 王莹 Rapid emergency anesthesia machine for ICU (intensive care unit) department
CN105233383A (en) * 2015-09-12 2016-01-13 张萍 Foldable anesthesia machine with automatic warning device
CN106955403A (en) * 2017-03-15 2017-07-18 中国人民解放军第三军医大学第二附属医院 A kind of closed loop inhalation anesthesia control system
CN108904941A (en) * 2018-06-12 2018-11-30 深圳市人民医院 A kind of intelligent operation anesthesia management system
CN211213107U (en) * 2019-11-23 2020-08-11 成都市龙泉驿区第一人民医院 Anesthesia depth monitoring device for anesthesia
CN112354055A (en) * 2020-11-03 2021-02-12 遵义医科大学 Inhalation type continuous anesthesia system with adjustable dosage and method

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Application publication date: 20210810