CN113208936A - Whitening gel and using method thereof - Google Patents
Whitening gel and using method thereof Download PDFInfo
- Publication number
- CN113208936A CN113208936A CN202110397105.5A CN202110397105A CN113208936A CN 113208936 A CN113208936 A CN 113208936A CN 202110397105 A CN202110397105 A CN 202110397105A CN 113208936 A CN113208936 A CN 113208936A
- Authority
- CN
- China
- Prior art keywords
- whitening gel
- total weight
- teeth
- percent
- finishing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dental Preparations (AREA)
- Cosmetics (AREA)
Abstract
The invention provides a whitening gel which comprises the components of hydrogen peroxide, silver ions, potassium chloride, sodium bicarbonate, EDTA (ethylene diamine tetraacetic acid), saccharin sodium, carbomer U20, triethanolamine and purified water. The whitening gel mainly comprises substances such as hydrogen peroxide and silver ions, is continuously kept at a specific part of teeth and gums by means of a special denture base, has the effects of killing and removing bacteria and pigment products at the contacted part, can permeate into the teeth for sterilization to clean the teeth and the gums, and has the soft and white effect that the teeth are seen from the outside to the inside by naked eyes.
Description
Technical Field
The invention relates to the technical field of whitening gel, in particular to whitening gel and a using method thereof.
Background
Tooth whitening refers to a process of whitening teeth by placing a chemical oxidative bleaching medicament on the surface or inside the teeth and carrying out a chemical reaction with the teeth, or adhering an object on the surface of the teeth to cover the natural color of the teeth, and the teeth are whitened mainly by cold light tooth whitening, laser tooth whitening and ultrasonic tooth cleaning.
Different whitening substances are often used in the process of whitening teeth, and with the increasing pursuit of people for whitening teeth, a whitening gel gradually appears in the market at present, but due to the incomplete technology, the preparation and the use method of the whitening gel have some defects, so that the whitening gel and the use method thereof are provided.
Disclosure of Invention
In order to solve the technical problems, the invention provides a whitening gel and a using method thereof, which are achieved by the following specific technical means:
the invention adopts the following technical scheme for realizing the technical purpose: the whitening gel consists of the following raw materials in parts by weight:
hydrogen peroxide: 2% -4% of the total weight;
silver ion: 0.0003% -0.0005% of the total weight of the composition;
potassium chloride: 0.1 to 0.3 percent of the total weight;
sodium bicarbonate: 0.05 to 0.15 percent of the total weight;
EDTA: 0.04 to 0.06 percent;
sodium saccharin: 0.02% -0.04% of the total weight of the mixture;
carbomer U20: 0.4 to 0.6 percent of the total weight;
triethanolamine: 0.4 to 0.6 percent of the total weight;
purifying water: 94% -96% of the total weight.
Preferably, the hydrogen peroxide is an oxidizing agent, can kill bacteria, is a mature product, has the effect of decomposing pigments, can bleach teeth under the guidance of medical advice, can remove dental plaque by killing bacteria to achieve the aim of preventing dental caries and periodontal inflammation, can treat early enamel dental caries, and provides the possibility of remineralization and repair.
Preferably, the silver ions are antibacterial agents, have the advantages of safety, broad spectrum, long-acting property, no resistant bacteria and remarkable antibacterial effect, and are very ideal antibacterial agents. The disadvantages are that silver ion is unstable and the processing cost is high. The silver ion is non-resistant bacteria, i.e. the bacteria have no resistance to silver ions. This is due to the unique bactericidal mechanism of silver ions.
Preferably, the sodium bicarbonate alkaline substance, commonly called as the orine, has the effects of nourishing the stomach and treating hyperacidity, does not corrode teeth, and has a certain adjuvant therapy effect on gingivitis and periodontitis.
Preferably, the sodium bicarbonate alkaline substance is white crystalline small-particle powder, and the potassium chloride is a clinically common electrolyte balance regulating drug, has definite clinical curative effect and is widely applied to various clinical departments.
According to the whitening gel, the use method of the whitening gel is provided, and comprises the following steps:
s1, weighing the raw materials according to the formula ratio, and fully mixing hydrogen peroxide, silver ions, potassium chloride, sodium bicarbonate, EDTA (ethylene diamine tetraacetic acid), saccharin sodium, carbomer U20, triethanolamine and water to obtain a whitening gel;
s2, making a plaster model of the teeth of the patient, and finishing a clear plaster model of the gingival sulcus;
s3, taking a plaster model, trimming and deepening a gingival sulcus, attaching an adhesive tape, trimming the adhesive tape at a high point 2 mm above a gingiva and 1 mm below a incisal margin, and trimming and attaching the adhesive tape at a single surface on the plaster model according to the tooth condition;
s4, pressing the film by using a soft film vacuum film pressing machine with the thickness of 1.5 mm, and finishing;
s5, finishing the individual denture and finishing the medicine storage tank;
s6, dripping whitening gel into the dental film medicine storage pool, and putting into the mouth.
Advantageous effects
Compared with the prior art, the invention provides a whitening gel and a using method thereof, and the whitening gel has the following beneficial effects:
1. the whitening gel mainly comprises substances such as hydrogen peroxide and silver ions, is continuously kept at a specific part of teeth and gums by a special denture base, has the effects of killing and removing bacteria and pigment products at the contacted part, can permeate into the teeth for sterilization, achieves the cleaning of the teeth and the gums, has the effect of soft and white teeth from the outside to the inside visible to the naked eyes, and is simple to prepare and clear in composition of various components.
2. The whitening gel product is mainly characterized by sterilization and depigmentation, the change of teeth can be seen by naked eyes in 20-hour in-vitro tooth test, the teeth are damaged or the congenital factors can cause that a few patients have slight discomfort, the problem can be solved by reducing the using time or enlarging the interval each time, if the patients have the tooth bleaching requirement, multiple treatment courses can be performed, but the interval between every two treatment courses is 3 days, so that the patients are not uncomfortable, and the product is matched with a paper colorimetric plate and can be used for comparison.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention is further described below by way of examples:
the first embodiment is as follows:
the whitening gel comprises hydrogen peroxide, silver ions, potassium chloride, sodium bicarbonate, EDTA, saccharin sodium, carbomer U20, triethanolamine, and purified water.
The hydrogen peroxide is an oxidant, can kill bacteria, is a mature product, has the function of decomposing pigments, can bleach teeth, can remove dental plaque by killing bacteria under the guidance of medical advice to achieve the aim of preventing decayed teeth and periodontitis inflammation, can treat early enamel decayed teeth, and provides the possibility of remineralization and repair.
The silver ions are antibacterial agents, have the advantages of safety, broad spectrum, long-acting property, anepitressive bacteria and remarkable antibacterial effect, and are very ideal antibacterial agents. The disadvantages are that silver ion is unstable and the processing cost is high. The silver ion is non-resistant bacteria, i.e. the bacteria have no resistance to silver ions. This is due to the unique bactericidal mechanism of silver ions.
The sodium bicarbonate alkaline substance is commonly called as the oridine, has the effects of nourishing the stomach and treating hyperacidity, does not corrode teeth, and has a certain adjuvant therapy effect on gingivitis and periodontitis.
The sodium bicarbonate alkaline substance potassium chloride is white crystallized small-particle powder, is a clinically common electrolyte balance regulating drug, has definite clinical curative effect and is widely applied to various clinical departments.
According to the whitening gel, the use method of the whitening gel is provided, and comprises the following steps:
s1, preparing the following raw materials in percentage by mass:
2% of hydrogen peroxide, 0.0003% of silver ions, 0.1% of potassium chloride, 0.05% of sodium bicarbonate, 0.04% of EDTA, 0.02% of saccharin sodium, carbomer U20: 0.4 percent of triethanolamine, 0.4 percent of purified water 96 percent
S2, weighing the raw materials according to the formula ratio, and fully mixing hydrogen peroxide, silver ions, potassium chloride, sodium bicarbonate, EDTA (ethylene diamine tetraacetic acid), saccharin sodium, carbomer U20, triethanolamine and water to obtain a whitening gel;
s3, making a plaster model of the teeth of the patient, and finishing a clear plaster model of the gingival sulcus;
s4, taking a plaster model, trimming and deepening a gingival sulcus, attaching an adhesive tape, trimming the adhesive tape at a high point 2 mm above a gingiva and 1 mm below a incisal margin, and trimming and attaching the adhesive tape at a single surface on the plaster model according to the tooth condition;
s5, pressing the film by using a soft film vacuum film pressing machine with the thickness of 1.5 mm, and finishing;
s6, finishing the individual denture and finishing the medicine storage tank;
s7, dripping whitening gel into the dental film medicine storage pool, and putting into the mouth.
Example two:
according to the whitening gel, the use method of the whitening gel is provided, and comprises the following steps:
s1, preparing the following raw materials in percentage by mass:
3% of hydrogen peroxide, 0.0004% of silver ions, 0.2% of potassium chloride, 0.1% of sodium bicarbonate, 0.05% of EDTA, 0.03% of saccharin sodium, carbomer U20: 0.5 percent of triethanolamine, 0.5 percent of purified water 95 percent
S2, weighing the raw materials according to the formula ratio, and fully mixing hydrogen peroxide, silver ions, potassium chloride, sodium bicarbonate, EDTA (ethylene diamine tetraacetic acid), saccharin sodium, carbomer U20, triethanolamine and water to obtain a whitening gel;
s3, making a plaster model of the teeth of the patient, and finishing a clear plaster model of the gingival sulcus;
s4, taking a plaster model, trimming and deepening a gingival sulcus, attaching an adhesive tape, trimming the adhesive tape at a high point 2 mm above a gingiva and 1 mm below a incisal margin, and trimming and attaching the adhesive tape at a single surface on the plaster model according to the tooth condition;
s5, pressing the film by using a soft film vacuum film pressing machine with the thickness of 1.5 mm, and finishing;
s6, finishing the individual denture and finishing the medicine storage tank;
s7, dripping whitening gel into the dental film medicine storage pool, and putting into the mouth.
Example three:
according to the whitening gel, the use method of the whitening gel is provided, and comprises the following steps:
s1, preparing the following raw materials in percentage by mass:
4% of hydrogen peroxide, 0.0005% of silver ions, 0.3% of potassium chloride, 0.15% of sodium bicarbonate, 0.06% of EDTA, 0.04% of saccharin sodium, carbomer U20: 0.6 percent of triethanolamine, 0.6 percent of purified water 94 percent
S2, weighing the raw materials according to the formula ratio, and fully mixing hydrogen peroxide, silver ions, potassium chloride, sodium bicarbonate, EDTA (ethylene diamine tetraacetic acid), saccharin sodium, carbomer U20, triethanolamine and water to obtain a whitening gel;
s3, making a plaster model of the teeth of the patient, and finishing a clear plaster model of the gingival sulcus;
s4, taking a plaster model, trimming and deepening a gingival sulcus, attaching an adhesive tape, trimming the adhesive tape at a high point 2 mm above a gingiva and 1 mm below a incisal margin, and trimming and attaching the adhesive tape at a single surface on the plaster model according to the tooth condition;
s5, pressing the film by using a soft film vacuum film pressing machine with the thickness of 1.5 mm, and finishing;
s6, finishing the individual denture and finishing the medicine storage tank;
s7, dripping whitening gel into the dental film medicine storage pool, and putting into the mouth.
Comparative example one:
according to the whitening gel, the use method of the whitening gel is provided, and comprises the following steps:
s1, preparing the following raw materials in percentage by mass:
5% of hydrogen peroxide, 0.0006% of silver ions, 0.4% of potassium chloride, 0.2% of sodium bicarbonate, 0.07% of EDTA, 0.05% of saccharin sodium, carbomer U20: 0.7 percent of triethanolamine, 0.7 percent of purified water 93 percent
S2, weighing the raw materials according to the formula ratio, and fully mixing hydrogen peroxide, silver ions, potassium chloride, sodium bicarbonate, EDTA (ethylene diamine tetraacetic acid), saccharin sodium, carbomer U20, triethanolamine and water to obtain a whitening gel;
s3, making a plaster model of the teeth of the patient, and finishing a clear plaster model of the gingival sulcus;
s4, taking a plaster model, trimming and deepening a gingival sulcus, attaching an adhesive tape, trimming the adhesive tape at a high point 2 mm above a gingiva and 1 mm below a incisal margin, and trimming and attaching the adhesive tape at a single surface on the plaster model according to the tooth condition;
s5, pressing the film by using a soft film vacuum film pressing machine with the thickness of 1.5 mm, and finishing;
s6, finishing the individual denture and finishing the medicine storage tank;
s7, dropping whitening gel into the dental film medicine storage pool and putting into the mouth
And (3) whitening test:
four experimenters are selected, the teeth of the four experimenters are required to be basically adhered with the same degree of pigment, the four volunteers are coated with the same amount of the sample whitening gel of the first example, the second example, the third example and the first comparative example according to the operation steps, and then the following results are obtained after the test:
| test specimen | Degree of pigment removal | Whitening effect of teeth | Time required for tooth whitening |
| Example one | 86% | Good wine | 35 minutes |
| Example two | 90% | Superior food | 32 minutes |
| EXAMPLE III | 95% | Superior food | 24 minutes |
| Comparative example 1 | 72% | Good wine | 40 minutes |
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. A whitening gel characterized by: the composite material consists of the following raw materials in parts by weight:
hydrogen peroxide: 2% -4% of the total weight;
silver ion: 0.0003% -0.0005% of the total weight of the composition;
potassium chloride: 0.1 to 0.3 percent of the total weight;
sodium bicarbonate: 0.05 to 0.15 percent of the total weight;
EDTA: 0.04 to 0.06 percent;
sodium saccharin: 0.02% -0.04% of the total weight of the mixture;
carbomer U20: 0.4 to 0.6 percent of the total weight;
triethanolamine: 0.4 to 0.6 percent of the total weight;
purifying water: 94% -96% of the total weight.
2. The whitening gel of claim 1, wherein: the hydrogen peroxide is an oxidizing agent.
3. The whitening gel of claim 1, wherein: the silver ions are antibacterial agents.
4. The whitening gel of claim 1, wherein: the sodium bicarbonate alkaline substance.
5. The whitening gel of claim 1, wherein: the sodium bicarbonate alkaline substance and the potassium chloride are white crystalline small-particle powder.
6. The whitening gel according to claim 1, wherein the use method of the whitening gel is characterized by comprising the following steps:
s1, weighing the raw materials according to the formula ratio, and fully mixing hydrogen peroxide, silver ions, potassium chloride, sodium bicarbonate, EDTA (ethylene diamine tetraacetic acid), saccharin sodium, carbomer U20, triethanolamine and water to obtain a whitening gel;
s2, making a plaster model of the teeth of the patient, and finishing a clear plaster model of the gingival sulcus;
s3, taking a plaster model, trimming and deepening a gingival sulcus, attaching an adhesive tape, trimming the adhesive tape at a high point 2 mm above a gingiva and 1 mm below a incisal margin, and trimming and attaching the adhesive tape at a single surface on the plaster model according to the tooth condition;
s4, pressing the film by using a soft film vacuum film pressing machine with the thickness of 1.5 mm, and finishing;
s5, finishing the individual denture and finishing the medicine storage tank;
s6, dripping whitening gel into the dental film medicine storage pool, and putting into the mouth.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110397105.5A CN113208936A (en) | 2021-04-13 | 2021-04-13 | Whitening gel and using method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110397105.5A CN113208936A (en) | 2021-04-13 | 2021-04-13 | Whitening gel and using method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113208936A true CN113208936A (en) | 2021-08-06 |
Family
ID=77087109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110397105.5A Pending CN113208936A (en) | 2021-04-13 | 2021-04-13 | Whitening gel and using method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113208936A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1809322A (en) * | 2003-06-18 | 2006-07-26 | 牙周保护有限责任公司 | Periodontal medicament delivery tray |
| CN101347388A (en) * | 2008-02-27 | 2009-01-21 | 徐阳波 | Oral cavity nursing agent and preparation technique thereof |
| EP2332514A1 (en) * | 2009-12-14 | 2011-06-15 | Henkel AG & Co. KGaA | Antibacterial oral and tooth care and cleaning agents with silver |
| CN202113185U (en) * | 2011-05-11 | 2012-01-18 | 王艺然 | Gum cover capable of containing paste |
| CN108542800A (en) * | 2018-07-07 | 2018-09-18 | 广东第二师范学院 | A kind of tooth whitening gel and its preparation and application |
| CN109806019A (en) * | 2017-11-22 | 2019-05-28 | 山东菏泽振华精密模具有限公司 | A kind of injection molding denture fixing device and production method |
-
2021
- 2021-04-13 CN CN202110397105.5A patent/CN113208936A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1809322A (en) * | 2003-06-18 | 2006-07-26 | 牙周保护有限责任公司 | Periodontal medicament delivery tray |
| CN101347388A (en) * | 2008-02-27 | 2009-01-21 | 徐阳波 | Oral cavity nursing agent and preparation technique thereof |
| EP2332514A1 (en) * | 2009-12-14 | 2011-06-15 | Henkel AG & Co. KGaA | Antibacterial oral and tooth care and cleaning agents with silver |
| CN202113185U (en) * | 2011-05-11 | 2012-01-18 | 王艺然 | Gum cover capable of containing paste |
| CN109806019A (en) * | 2017-11-22 | 2019-05-28 | 山东菏泽振华精密模具有限公司 | A kind of injection molding denture fixing device and production method |
| CN108542800A (en) * | 2018-07-07 | 2018-09-18 | 广东第二师范学院 | A kind of tooth whitening gel and its preparation and application |
Non-Patent Citations (1)
| Title |
|---|
| 潘海阳, 北京金盾出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU708145B2 (en) | Method for preparing a preparation for bleaching teeth or for treating skin complaints and mucous membrane disorders | |
| US4708864A (en) | Method and compositions for treating dental structures | |
| CN101370475A (en) | Treating and preventing preparation used for oral nursing | |
| US3907991A (en) | Methods of killing certain bacteria and fungi and diminishing dental plaque | |
| WO2023051478A1 (en) | Dental gel having remineralizing ability, dental patch, and method for preparing dental gel | |
| CN112618413A (en) | Oral product containing hyaluronic acid and preparation method thereof | |
| US5738113A (en) | Caries treatment method with fluoride | |
| CA2398639A1 (en) | Compositions and methods for whitening and desensitizing teeth | |
| Leverett et al. | Effect of daily rinsing with stannous fluoride on plaque and gingivitis | |
| CN110302065A (en) | A kind of whitening strips and its preparation process containing photocatalyst | |
| Amer | Intracoronal tooth bleaching–A review and treatment guidelines | |
| CN113208936A (en) | Whitening gel and using method thereof | |
| JPS61286314A (en) | Composition for oral cavity | |
| Porwal et al. | Comparative evaluation of the effect of Chlorhexidine Gluconate, raw Propolis and hydrogen peroxide on dental plaque and gingival inflammation | |
| Tamaki et al. | Study of the clinical usefulness of a dental drug system for selective reduction of mutans streptococci using a case series | |
| CN109044933B (en) | Application of dragon's blood extract in preparing toothpaste for inhibiting dental plaque | |
| EP2906179B1 (en) | Topical ubiquinol oral supplement compositions with amorphous calcium phosphate | |
| KR20120054297A (en) | Oral composition containing extract of sapindus mukurossi gaertn | |
| RU2637411C1 (en) | Gingival plate for treatment of gyngivit and parodontitis | |
| US8936778B2 (en) | Methods for bleaching and desensitizing teeth | |
| Pasiga et al. | Clinical effects of alkaline ionization water (AIW) as a mouthwash against the reduction of dental plaque | |
| JPS62240609A (en) | Composition for oral cavity application | |
| JP2003231642A (en) | Agent for treatment of periodontosis, agent for treatment of endodontosis, dental material and denture cleaning agent | |
| CN112773727B (en) | Preparation method of stain-removing whitening biological lysozyme toothpaste composition | |
| Leverett et al. | The Effect of Daily Mouthrinsing with Stannous Fluoride on Dental Plaque and Gingivitis—Four-month Results |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |