CN113164379B - 用于递送活性剂的可生物降解脂质 - Google Patents

用于递送活性剂的可生物降解脂质 Download PDF

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CN113164379B
CN113164379B CN201980077559.5A CN201980077559A CN113164379B CN 113164379 B CN113164379 B CN 113164379B CN 201980077559 A CN201980077559 A CN 201980077559A CN 113164379 B CN113164379 B CN 113164379B
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lipid
lipid particle
particle
cationic
group
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CN113164379A (zh
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穆图萨米·贾亚拉曼
何果
马丁·迈尔
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Alnylam Pharmaceuticals Inc
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Alnylam Pharmaceuticals Inc
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    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/06—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having the hydroxy groups esterified by carboxylic acids having the esterifying carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms of an acyclic saturated carbon skeleton
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