CN113144319A

CN113144319A - Intelligent blood activating instrument

Info

Publication number: CN113144319A
Application number: CN202110427283.8A
Authority: CN
Inventors: 彭罗民; 陈文�; 彭程
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-04-21
Filing date: 2021-04-21
Publication date: 2021-07-23
Also published as: CN115212371A

Abstract

The intelligent blood activating instrument is short for medical intelligent ultraviolet irradiation oxygenation autoblood transfusion therapy (UBIO). Can be used for clinical treatment of bacterial, fungal and viral infection, immunologic hypofunction, poisoning, etc. The novel coronavirus (COVID-19) is a virus, a re-mutation or a virus, and is effective for ultraviolet irradiation treatment according to the characteristics of the virus. UBIO is also effective in treating ischemia, hypoxic diseases, diabetes and complications. The invention is composed of a reciprocating blood circulation system; an oxygen delivery exhaust system; an ultraviolet irradiation system; a bracket system of the movable blood activation chamber and a software working program system of the intelligent blood activation instrument. The invention is characterized in that the closed blood reciprocating circulation ultraviolet irradiation is automatically and continuously carried out, which is more in line with the medical specification.

Description

Intelligent blood activating instrument

(I) technical field

The invention relates to a medical device, in particular to an intelligent blood activating instrument, which is mainly used for: 1. various infectious diseases were treated according to the national ministry of health document, hospital and care (2005) No. 92, including: the clinical treatment of bacterial, fungal and viral infection, immunologic hypofunction, poisoning and the like. The peritoneal dialysis technology in nephrology department and blood purification specialty is not popular enough in China, the important reason is abdominal cavity infection and peritonitis, and the treatment aiming at the peritonitis by the invention can avoid the risks of complication and multiple infection caused by antibiotics; 2. "new coronavirus (covi-19) is a virus, and whether the new coronavirus is a re-mutation or a virus, and ultraviolet irradiation is applied for treatment, the treatment is supposed to be effective according to the principle, although no example report for treatment and rescue of new coronavirus infection exists at home and abroad up to now, experts in the industry actively recommend that experts can perform clinical practice, and the experts are in the market. ECMO treatment is artificial respiration maintenance and does not achieve the goals of resisting viral infectious inflammation and enhancing immunity; the intelligent blood activating instrument applying the UBIO principle treats and rescues new coronavirus infection, can resist virus infection, can improve the anoxic state of a patient due to rapid and direct oxygenation to blood, and promotes body recovery; 3. according to the clinical practice data of the people in the industry, except the treatment scope described in the No. 92 document of the Ministry of health (2005), the ultraviolet irradiation oxygenation autoblood return transfusion therapy (UBIO) obtains safe and reliable curative effect on the treatment of cardiovascular and cerebrovascular diseases and complications thereof, diabetes mellitus and complications thereof, and the like. The invention is characterized in that the invention is invented in Chinese patent with the name: blood stimulation apparatus, patent No.: intelligent product upgrading concept design based on ZL 200610067536.0. The whole-course operation is a closed blood circulation process, meets the requirements of clinical technical operation standards, and is simple, safe, stable and reliable.

(II) background of the invention

The background art name is according to the national ministry of health document, doctor wei fa (2005)92, the essential meaning is: the ultraviolet irradiation oxygenation self-blood return transfusion therapy is simply called as follows: "UBIO", blood therapy ". The method is confirmed by the No. 92 file of medical health department (2005) of the national ministry of health, proves that the method is safe and effective in clinical application, and can be used for clinical treatment methods of bacterial, fungal and viral infection, low immune function, poisoning and the like. Although the background technology of UBIO is safe and reliable in curative effect, the existing instrument and equipment are too complicated to operate. Patent according to chinese utility model, patent number: 02202894.3 and the patent of the invention in China, patent number: 02100561.3, in the clinical practice, only the "autoblood ultraviolet irradiation reinfusion therapy (UBIO)" is performed from the venous blood collection and treatment of the patient to the reinfusion of the patient, which requires many times of connecting the catheters, thus wasting manpower, material resources and time, and more importantly, increasing the chance of pollution; furthermore, the treatment site must be of sufficiently large area that the apparatus cannot be moved to the patient's bedside. Chinese invention patent, patent number: 200610067536.0 overcomes the disadvantages of the above two patents, and reduces the problems that many operations are performed by connecting a plurality of catheters, and the device can be pushed to the side of the patient bed, but the operation process is still intermittent and continuous manual operation, and each therapist needs to have the whole monitoring and control of the medical care personnel. The invention overcomes the defects of the patents, realizes the whole-process intelligent monitoring after starting, and one medical care personnel can simultaneously monitor a plurality of patients. In particular to the rescue treatment of critical patients and the treatment of virus-infected infectious patients, medical and nursing personnel can automatically monitor the treatment period without needing to guard around the curer in the whole process, thereby greatly improving the treatment work efficiency and improving the treatment effect. If the traditional Chinese medicine composition is used for clinically treating patients infected with new coronary pneumonia, nephritis and the like infected by new coronary viruses, unexpected and unexpected good effects can be achieved.

Disclosure of the invention

The intelligent blood activating instrument is a blood transfusion tube which introduces human venous blood into medical high molecular material through a puncture needle, and then introduces the blood into a blood container which is made of high molecular material and can transmit ultraviolet rays through the blood transfusion tube by utilizing natural falling potential difference and gravity; ultraviolet lamps with specific wave bands are arranged in the upper space and the lower space of the blood container, and the blood in the blood container is irradiated when the ultraviolet lamps are turned on; the venous blood enters a blood container, is continuously irradiated by ultraviolet rays and continuously oxygenated for a certain time to achieve the purpose of activating the blood, and the activated blood is returned to a therapist by utilizing the principles of atmospheric pressure, gravity and falling head; after the blood activation treatment, the automatic operation of the next period is carried out, and the blood circulates back and forth until the treatment program is finished; designing specific therapeutic dose according to individual actual age, sex, weight and diagnosis of the patient; the treatment operation and the treatment process adopt artificial intelligence, and the intelligent blood activating instrument is integrally designed, designed and manufactured;

the invention is characterized in that: the blood reciprocating circulation system is formed by connecting a puncture needle (1) with a blood transfusion catheter (2), and connecting the blood transfusion catheter (2) with one end of a blood container (3);

the medical oxygen conveying system is formed by connecting an oxygen input pipe (4) and an oxygen discharge pipe (5) with two ends of one side of the upper surface of a blood container (3), wherein before the oxygen input pipe (4) is connected with the blood container (3), the oxygen input pipe is connected with an oxygen source regulating valve (7) through an oxygen filter (6), and the oxygen source regulating valve (7) is arranged on an oxygen source device (8);

thirdly, an ultraviolet irradiation system is designed and installed in the space of the upper surface and the lower surface of the blood container (3) and ultraviolet lamps (9 and 10) with specific wave bands are installed, the ultraviolet lamps (9 and 10) are turned on, and ultraviolet light quanta can irradiate the venous blood entering the blood container (3) through the blood container (3) made of high molecular materials which can transmit ultraviolet rays;

a movable blood activation chamber bracket system which is formed by connecting a support column (11) with a chassis (12), wherein the top end of the support column (11) is provided with an illuminating lamp (13), the lower part of the support column chassis (12) is provided with four universal wheels (12-1, 12-2, 12-3, 12-4), an up-and-down moving ring (14) is arranged on the body of the support column (11), the up-and-down moving ring (14) is connected with a movable blood activation chamber (15), the upper part of the blood activation chamber (15) is provided with a microcomputer and an operation button (16), a power line and a power plug (17) are connected with a cable (18), and the cable (18) is connected with the movable blood activation chamber (15);

fifthly, the normal saline flushing system consists of an infusion support (19), a liquid suspension arm (19-1) connected with the infusion support and an infusion regulating valve (19-2), a normal saline container or an infusion bag (20) is suspended on a hook of the liquid suspension arm (19-1) added on an infusion branch, an infusion catheter (21) is connected with the normal saline container or the infusion bag (20), the infusion catheter (21) is connected with the end A (21-A) of a three-way pipe (21) after passing through the infusion regulating valve (19-2), the end B (21-B) of the three-way pipe (21) is provided with a regulating valve (22), the end C (21-C) of the three-way pipe (21) is connected with a blood transfusion catheter (2) connected with the limb of a patient, and the systems jointly form an intelligent blood activating instrument;

the software working procedure of the intelligent blood activating instrument is as follows: the operation is started, a normal saline container or an infusion bag (20) is manually placed on a hook of a liquid suspension arm (19-1), an infusion catheter (21) is placed in an infusion regulating valve (19-2), a blood container (3) is placed in a movable blood activation chamber (15), the normal saline is opened, the infusion catheter (21) and a blood transfusion catheter (2) are washed, air in the catheters is exhausted, a puncture needle (1) is pre-filled, and a blood sampling, infusion and transfusion passage is established for puncture of a therapist;

a clockwise and anticlockwise rotation motor (24) of the intelligent blood activating instrument is started, and a transmission shaft chain (25) enables the blood activating chamber (15) to be lowered to a low position so as to collect venous blood by using a falling head; an automatic inflating tourniquet (26) is arranged on the upper arm of the upper limb to be punctured, the inflation degree reaches the diastolic pressure level of a therapist, venous blood backflow can be prevented to the limit, arterial blood flow does not need to be blocked, the puncture is successful, the therapist regularly makes a fist and a fist, and venous blood is promoted to flow from a puncture needle (1) → a needle tail tube → a blood transfusion catheter (2) → a blood container (3); an oxygen source regulating valve (7) is opened, medical oxygen passes through an oxygen input pipe (4), passes through an oxygen filtering and sterilizing device (6) and reaches a blood container (3), the oxygen fully acts with blood in the blood container (3) and is simultaneously irradiated by ultraviolet rays, and the rest part of the oxygen is discharged out of the blood container (3) from an oxygen discharge pipe (5); after the blood sampling amount reaches the design amount of the prescription, the clockwise and anticlockwise rotation motor (24) drives the transmission shaft chain (25) to automatically make the blood activation chamber (15) rise to a high position, and the ultraviolet irradiation and oxygenation treatment are continuously carried out; meanwhile, the three-way regulating valve (22) on the blood transfusion pipe (2) is closed, the transfusion regulating valve (19-2) is automatically opened, and the physiological saline flows out to discharge the blood which is not activated and treated in the blood transfusion pipe (2) into the body of a treated person; after the venous blood activation treatment time in the blood activation chamber (15) reaches the prescribed setting time; the three-way regulating valve (22) on the blood transfusion catheter (2) is opened, the activated blood in the blood activation chamber (15) flows out, passes through the blood transfusion catheter (2), flows back to the puncture needle tail pipe, and flows back to the body of a treated person through the puncture needle (1), thereby completing a blood activation and back transfusion procedure;

when the blood container (3) in the blood activation chamber (15) is activated to be empty, the microcomputer and the operation button (16) receive the information of the blood activation chamber (15), instruct the clockwise and anticlockwise rotation motor (24), the transmission shaft chain (25) enables the blood activation chamber (15) to be lowered to the low position, the automatic inflation tourniquet (26) is inflated to reach the diastolic pressure level, the oxygen regulating valve (23) is opened, the three-way regulating valve (22) on the blood transfusion catheter is opened, the transfusion regulating valve (19-2) is automatically closed, blood collection is started, blood flows out from the puncture needle (1) to the tail tube, and the next round of blood activation treatment program is repeatedly carried out until the treatment dosage designed by the prescription is completed.

(IV) description of the drawings

FIG. 1 is a blood reciprocating circulating system of an intelligent blood activating instrument, which is formed by connecting a puncture needle (1) with a blood transfusion tube (2), and connecting the blood transfusion tube (2) with one end of a blood container (3);

FIG. 2 is a diagram of a medical oxygen delivery system, which is formed by connecting an oxygen input tube (4) and an oxygen discharge tube (5) with two ends of one side of the upper surface of a blood container (3), wherein the oxygen input tube (4) is connected with the blood container (3) through an oxygen filter (6) and then is connected with an oxygen source regulating valve (7), and the oxygen source regulating valve (7) is arranged on an oxygen source device (8);

FIG. 3 is a view showing an ultraviolet irradiation system, in which ultraviolet lamps (9, 10) having specific wavelength bands are installed in the upper and lower spaces of a blood container (3), and when the ultraviolet lamps (9, 10) are turned on, ultraviolet light quanta are irradiated with ultraviolet rays from the venous blood entering the blood container (3) through the blood container (3) made of a high molecular material which can transmit ultraviolet rays;

FIG. 4 is a bracket system of a mobile blood activating chamber, which is formed by connecting a support (11) with a chassis (12), wherein the top end of the support (11) is provided with an illuminating lamp (13), the lower part of the support chassis (12) is provided with four universal wheels (12-1, 12-2, 12-3, 12-4), an up-and-down moving ring (14) is arranged on the body of the support (11), the up-and-down moving ring (14) is connected with the mobile blood activating chamber (15), the upper part of the blood activating chamber (15) is provided with a microcomputer and an operating button (16), a power line and a power plug (17) are connected with a cable (18), and the cable (18) is connected with the mobile blood activating chamber (15);

FIG. 5 is a software operating program system of the intelligent blood activation instrument; starting and moving the blood activation chamber (15) to rise to a high position; manually placing a normal saline container or an infusion bag (20) on a hook of a liquid suspension arm (19-1), placing an infusion catheter (21) in an infusion regulating valve (19-2), placing a blood container (3) in a mobile blood activation chamber (15), opening the normal saline, flushing the infusion catheter (21) and a blood transfusion catheter (2), and exhausting air in the catheters; the puncture needle (1) is pre-filled, and blood sampling, transfusion and transfusion passages are established for puncture of a therapist;

a clockwise and anticlockwise rotation motor (24) of the intelligent blood activating instrument is started, and a transmission shaft chain (25) enables the blood activating chamber (15) to be lowered to a low position so as to collect venous blood by using a falling head; an automatic inflating tourniquet (26) is arranged on the upper arm of the upper limb to be punctured, the inflation degree reaches the diastolic pressure level of a therapist, venous blood backflow can be prevented to the limit, arterial blood flow does not need to be blocked, the puncture succeeds, the therapist regularly makes and puts a fist, and venous blood is promoted to flow from a puncture needle (1) to a needle tail tube blood transfusion catheter (2) to a blood container (3); an oxygen source regulating valve (7) is opened, medical oxygen passes through an oxygen input pipe (4), passes through an oxygen filtering and sterilizing device (6) and reaches a blood container (3), the oxygen fully acts with blood in the blood container (3) and is simultaneously irradiated by ultraviolet rays, and the rest part of the oxygen is discharged out of the blood container (3) from an oxygen discharge pipe (5); after the blood sampling amount reaches the design amount of the prescription, the clockwise and anticlockwise rotation motor (24) drives the transmission shaft chain (25) to automatically make the blood activation chamber (15) rise to a high position, and the ultraviolet irradiation and oxygenation treatment are continuously carried out; meanwhile, the three-way regulating valve (22) on the blood transfusion catheter (2) is closed, the transfusion regulating valve (19-2) is automatically opened, and the physiological saline flows out to discharge the blood which is not activated in the blood transfusion catheter (2) into the human body; after the venous blood activation treatment time in the blood activation chamber (15) reaches the prescribed setting time; the three-way regulating valve (22) on the blood transfusion catheter (2) is opened, the oxygen regulating valve (23) is closed, the activated blood in the blood activation chamber (15) flows out, passes through the blood transfusion catheter (2), and flows back to the tail tube of the puncture needle, and flows back to the body through the puncture needle (1), thus completing a blood activation and return transfusion procedure;

when the blood container (3) in the blood activation chamber (15) is empty, the microcomputer and the operation button (16) receive the information that the blood activation chamber (15) is empty, namely the instruction is to rotate along with the clockwise and anticlockwise rotating motor (24), the transmission shaft chain (25) enables the blood activation chamber (15) to be lowered to the low position, the oxygen regulating valve (23) is opened, the three-way regulating valve (22) on the blood transfusion catheter (2) is opened, the transfusion regulating valve (19-2) is automatically closed, the automatic inflation tourniquet (26) is inflated to reach the diastolic pressure level of a treated person, blood sampling is restarted, and the next round of blood activation treatment program is repeatedly carried out until the treatment dosage designed by the prescription is completed.

(V) detailed description of the preferred embodiments

According to the description of fig. 1, prepare: (1) puncturing needle; (2) a blood transfusion tube; (3) a blood container;

according to the description of fig. 2, prepare: (4) an oxygen input tube; (5) an oxygen discharge pipe; (6) an oxygen filter (6); (7) an oxygen source regulating valve; (8) an oxygen source device;

according to the description of fig. 3, prepare: (9, 10) ultraviolet lamps of specific wave bands;

according to the description of fig. 4, prepare: (11) moving struts of the blood activation chamber stent system; (12) a chassis; (13) an illuminating lamp; (14) moving the ring; (15) moving the blood activation chamber; (16) a microcomputer and an operation button; (17) a power cord and a power plug; (18) a cable wire; (26) an automatic tourniquet;

according to the description of fig. 5, prepare: (19-1) a liquid suspension arm hook; (19-2) an infusion regulating valve; (20) a saline container or infusion bag; (21) an infusion catheter; (22) a three-way regulating valve; (23) an oxygen regulating valve; (24) clockwise and counter-clockwise rotating motors; (25) and a transmission shaft chain.

After the spare parts are prepared, the spare parts are assembled and installed according to the content described in the figures 1, 2, 3 and 4; designing a software program according to the content described in the figure 5, inputting the software program into a microcomputer, completing the debugging of the whole machine, and performing the trial operation of the whole machine; further clinical trial can be carried out. The medical consumable materials used in the invention are disposable consumable materials, and are produced and matched products in China.

The invention has the following positive effects: 1. because of the intelligent continuous treatment process, compared with the background technology, the blood volume of the treatment can be determined more flexibly and according to the requirement. Especially, the effect of continuous treatment on special virus infectious diseases, such as new coronary virus pneumonia, nephritis, early respiratory failure and the like, can have unexpected benefits without side reaction; 2. the treatment for cardiovascular and cerebrovascular complications caused by micro inflammation accompanied with terminal uremia caused by diabetes facing the professional of kidney and blood purification is probably superior to the effect of the current drug treatment; 3. for diseases caused by bacterial, fungal and general virus infection, the blood sampling amount of continuous treatment is larger than that of the background technology, and the quantitative change can bring qualitative change of the effect; 4. the treatment can improve the immunity of the body, and can possibly achieve the unexpected good effects on health care, rehabilitation, health preservation and anti-aging; 5. the invention is a small and flexible design, has no special requirements for the area of a treatment place, and can be adopted in all levels of medical institutions, community health centers, special clinics, blood purification centers, health care institutions and the like; 6. the product of the invention has low manufacturing cost and wide application range, and can greatly promote the big health industry of China; 7. the practical clinical operation and application method of the invention is that one person (therapist), one needle (puncture needle), one tube (blood transfusion and transfusion catheter) and one bag (blood container and bag) are continuously applied in one time until the treatment is completed, and the operation is not crossed with other persons midway, thus completely avoiding the occurrence of clinical accidents caused by cross contamination and error blood transfusion.

Claims

1. The intelligent blood activating instrument is one blood transfusion pipe to introduce human venous blood via puncture needle into medical polymer material and to introduce the blood into blood container of polymer material capable of permeating ultraviolet ray through natural falling head and gravitational attraction; ultraviolet lamps are arranged in the upper space and the lower space of the blood container, and the blood in the blood container is irradiated when the ultraviolet lamps are turned on; the venous blood enters a blood container, is continuously irradiated by ultraviolet rays and continuously oxygenated for a certain time to achieve the purpose of activating the blood, and the activated blood is returned to a therapist by utilizing the principles of atmospheric pressure, gravity and falling head; after the blood activation treatment, the automatic operation of the next period is carried out, and the blood circulates back and forth until the treatment program is finished; designing specific therapeutic dose according to individual actual age, sex, weight and diagnosis of the patient; the treatment operation and the treatment process adopt artificial intelligence, and the intelligent blood activating instrument is integrally designed, designed and manufactured; the invention is characterized in that: the blood reciprocating circulation system is formed by connecting a puncture needle (1) with a blood transfusion catheter (2), and connecting the blood transfusion catheter (2) with one end of a blood container (3); the medical oxygen conveying system is formed by connecting an oxygen input pipe (4) and an oxygen discharge pipe (5) with two ends of one side of the upper surface of a blood container (3), wherein before the oxygen input pipe (4) is connected with the blood container (3), the oxygen input pipe is connected with an oxygen source regulating valve (7) through an oxygen filter (6), and the oxygen source regulating valve (7) is arranged on an oxygen source device (8); thirdly, an ultraviolet irradiation system, wherein ultraviolet lamps (9, 10) with specific wave bands are designed and installed in the upper and lower two-side spaces of the blood container (3), the ultraviolet lamps (9, 10) are started, and ultraviolet light quanta can irradiate the venous blood entering the blood container (3) through the blood container (3) made of high polymer materials capable of transmitting ultraviolet rays; a movable blood activation chamber bracket system which is formed by connecting a support column (11) with a chassis (12), wherein the top end of the support column (11) is provided with an illuminating lamp (13), the lower part of the support column chassis (12) is provided with four universal wheels (12-1, 12-2, 12-3, 12-4), an up-and-down moving ring (14) is sleeved on the support column (11), the up-and-down moving ring (14) is connected with a movable blood activation chamber (15), the upper part of the blood activation chamber (15) is provided with a microcomputer and an operation button (16), a power line and a power plug (17) are connected with a cable (18), and the cable (18) is connected with the movable blood activation chamber (15); the normal saline flushing system is composed of an infusion support (19), a liquid suspension arm (19-1) connected with the infusion support and an infusion regulating valve (19-2), a normal saline container or an infusion bag (20) is suspended on a hook of the liquid suspension arm (19-1) added to an infusion support, an infusion catheter (21) is connected with the normal saline container or the infusion bag (20), the infusion catheter (21) is connected with an A end (21-A) of a three-way pipe (21) of the infusion catheter (21) after passing through the infusion regulating valve (19-2), a B end (21-B) of the three-way pipe (21) is provided with a regulating valve (22), and a C end (21-C) of the three-way pipe (21) is connected with a blood transfusion catheter (2) connected with the limb of a patient to jointly form an intelligent blood activating instrument device.

2. The software working procedure of the intelligent blood activating instrument is as follows: the operation is started, a normal saline container or an infusion bag (20) is manually placed on a hook of a liquid suspension arm (19-1), an infusion catheter (21) is placed in an infusion regulating valve (19-2), a blood container (3) is placed in a movable blood activation chamber (15), the normal saline is opened, the infusion catheter (21) and a blood transfusion catheter (2) are washed, air in the catheters is exhausted, a puncture needle (1) is pre-filled, and a blood sampling, infusion and transfusion passage is established for puncture of a therapist;

after the blood container (3) in the blood activation chamber (15) is activated to run empty, the microcomputer and the operation button (16) receive the information of the blood activation chamber (15), instruct the clockwise and anticlockwise rotation motor (24), the transmission shaft chain (25) enables the blood activation chamber (15) to be lowered to the low position, the automatic inflation tourniquet (26) is inflated to reach the diastolic pressure level, the oxygen regulating valve (23) is opened, the three-way regulating valve (22) on the blood transfusion catheter is opened, the transfusion regulating valve (19-2) is automatically closed, blood collection is started, blood flows out from the puncture needle (1) to the tail tube, and the next round of blood activation treatment program is repeatedly carried out until the treatment dosage designed by the prescription is completed.