CN112899145A - Portable device for avoiding aerosol pollution of nucleic acid detection - Google Patents

Portable device for avoiding aerosol pollution of nucleic acid detection Download PDF

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Publication number
CN112899145A
CN112899145A CN202110379498.7A CN202110379498A CN112899145A CN 112899145 A CN112899145 A CN 112899145A CN 202110379498 A CN202110379498 A CN 202110379498A CN 112899145 A CN112899145 A CN 112899145A
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nucleic acid
device shell
acid detection
air inlet
groove
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Chinese (zh)
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戴纳新
倪伟康
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Suzhou Weitelui Medical Equipment Co ltd
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Suzhou Weitelui Medical Equipment Co ltd
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Priority to CN202110379498.7A priority Critical patent/CN112899145A/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a portable device for avoiding aerosol pollution of nucleic acid detection, which comprises a device shell, wherein the front end of the device shell is provided with a rolling door, the right end of the device shell is provided with an installation groove, a dissolving box is detachably installed in the installation groove, a partition plate is arranged above the device shell, the center of the partition plate is provided with an air inlet, a fan is installed in a space formed by the partition plate and the device shell and is communicated with an air outlet pipe, and the air outlet pipe is connected with an air inlet head through a connecting hose. According to the invention, when nucleic acid is detected, the roller shutter door is closed, the sealed space is formed in the device shell under the action of the sealing strip and the sealing groove, the nucleic acid sample can be effectively prevented from diffusing into the air, the fan is opened, the nucleic acid sample in the device shell enters the dissolving box through the air inlet, the air outlet pipe and the air inlet head in sequence, and the nucleic acid sample is dissolved by the cleaning solution.

Description

Portable device for avoiding aerosol pollution of nucleic acid detection
Technical Field
The invention relates to the technical field of animal medical treatment, in particular to a portable device for avoiding aerosol pollution in nucleic acid detection.
Background
The detection of the virus nucleic acid is one of important methods for detecting the virus, when a nucleic acid sample of an animal is detected in detection centers such as a pet hospital or a laboratory, the detection result is influenced because the detection result is easy to show false positive due to the fact that the virus sample can diffuse into the air because the sample treatment is not standard and the indoor air mobility is poor, and the risk of aerosol infection is easily caused. The cost of setting up aseptic laboratory is higher, and the biological safety cabinet occupies a large amount of pet hospital spaces or usable air outlet of unsafe cabinet again, and the pet hospital urgently needs a portable equipment of avoiding the aerosol pollution.
Disclosure of Invention
The present invention is directed to a portable device for avoiding aerosol contamination in nucleic acid detection, which solves the above-mentioned problems of the prior art.
In order to achieve the purpose, the invention provides the following technical scheme:
a portable device for avoiding aerosol pollution of nucleic acid detection comprises a device shell, wherein the device shell is of a hollow structure and is arranged on a placing table, and a detection instrument for nucleic acid detection is arranged in the device shell, wherein:
the device comprises a device shell, a roller shutter door, an observation window, a dissolving box, an air inlet pipe, an air outlet pipe and an ultraviolet lamp, wherein the front end of the device shell is provided with the roller shutter door, the left end of the device shell is provided with the observation window, the right end of the device shell is provided with an installation groove, the dissolving box is detachably installed in the installation groove, the dissolving box is used for containing cleaning liquid for dissolving aerosol, the upper end of the dissolving box is provided with the air inlet pipe, a partition plate is arranged above the device shell, the center of the partition plate is provided with the air inlet, the lower end;
the front end and the rear end of the mounting groove are provided with clamping blocks through second sliding grooves in a sliding mode, one end, close to the dissolving box, of each clamping block is provided with a wedge-shaped surface, and a compression spring is fixedly mounted between the other end of each clamping block and the bottom of each second sliding groove.
Preferably, the lower extreme of rolling slats door is provided with the sealing strip with controlling both ends, both ends slidable mounting is in first spout about the rolling slats door, the lower extreme of device casing is equipped with the seal groove, is located the sealing strip and the seal groove sealing connection of rolling slats door lower extreme.
Preferably, the two ends of the connecting hose are fixedly provided with sealing connectors.
Preferably, the device shell is provided with a control panel, and the control panel comprises a counter and a warning lamp, wherein the counter is used for controlling the fan and the ultraviolet lamp control switch and counting the working times of the fan.
Preferably, a guide post is fixed at the center of one end of the clamping block close to the compression spring, the guide post is slidably mounted in a guide groove, and the guide groove is arranged at one end of the second chute far away from the dissolving box.
Compared with the prior art, the invention has the beneficial effects that:
1. according to the invention, when nucleic acid is detected, the roller shutter door is closed, a sealed space is formed in the device shell under the action of the sealing strip and the sealing groove, the nucleic acid sample can be effectively prevented from diffusing into the air, then the fan is opened, the nucleic acid sample in the device shell enters the dissolving box through the air inlet, the air outlet pipe and the air inlet head in sequence, the nucleic acid sample is dissolved by the cleaning solution, and meanwhile, the ultraviolet lamp further plays a role in sterilization and disinfection.
2. The dissolving box can be quickly installed in the installation groove through the wedge-shaped surface of the clamping block and the compression spring, the position of the dissolving box is fixed through the clamping block, and the dissolving box can be directly taken down when cleaning liquid fails, so that the dissolving box is convenient to replace.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic view of another embodiment of the present invention;
FIG. 3 is a schematic view of the internal structure of the present invention;
FIG. 4 is a schematic view of the control panel installation of the present invention;
FIG. 5 is a cross-sectional view of the overall construction of the present invention;
FIG. 6 is a schematic view of the structure of the mounting groove of the present invention.
In the figure: the device comprises a placing table 1, a device shell 2, a detector 3, a roller shutter door 4, a sealing strip 41, a first sliding groove 42, a sealing groove 43, an observation window 5, a mounting groove 6, a clamping block 61, a wedge-shaped surface 62, a second sliding groove 63, a compression spring 64, a guide pillar 65, a guide groove 66, a dissolving box 7, an air inlet head 71, a partition plate 8, an air inlet 9, a fan 10, an air outlet pipe 11, an ultraviolet lamp 12, a control panel 13, a control switch 14, a counter 15 and a warning lamp 16.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-6, the present invention provides a technical solution:
a portable device for avoiding aerosol pollution of nucleic acid detection comprises a device shell 2, wherein the device shell 2 is of a hollow structure and is arranged on a placing table 1, and a nucleic acid detection detector 3 is arranged in the device shell, and in the embodiment, the placing table 1 is a laboratory bench.
The front end of the device shell 2 is provided with a rolling shutter door 4, the left end of the device shell is provided with an observation window 5, the right end of the device shell is provided with a mounting groove 6, a dissolving box 7 is detachably mounted in the mounting groove 6, the dissolving box 7 is used for containing cleaning liquid for dissolving aerosol, the upper end of the dissolving box is provided with an air inlet 71, a partition plate 8 is arranged above the device shell 2, the center of the partition plate 8 is provided with an air inlet 9, the lower end of the partition plate is provided with an ultraviolet lamp 12, a fan 10 is mounted in a space formed by the partition plate 8 and the device shell 2 and communicated with an air outlet pipe.
The front end and the rear end of the mounting groove 6 are provided with clamping blocks 61 in a sliding manner through a second sliding groove 63, one end of each clamping block 61 close to the dissolving box 7 is provided with a wedge-shaped surface 62, and a compression spring 64 is fixedly arranged between the other end of each clamping block and the bottom of the second sliding groove 63. A guide post 65 is fixed at the center of one end of the clamping block 61 close to the compression spring 64, the guide post 65 is slidably mounted in a guide groove 66, and the guide groove 66 is arranged at one end of the second sliding groove 63 far away from the dissolving box 7.
The lower end and the left and right ends of the rolling door 4 are provided with sealing strips 41, the left and right ends of the rolling door 4 are slidably mounted in the first sliding groove 42, the lower end of the device shell 2 is provided with a sealing groove 43, and the sealing strips 41 and the sealing groove 43 at the lower end of the rolling door 4 are in sealing connection.
The two ends of the connecting hose are fixedly provided with sealing connectors, so that the dissolving box 7 can be conveniently reconnected after the dissolving box 7 is replaced.
The device shell 2 is provided with a control panel 13, and the control panel 13 comprises a control switch 14 for controlling the fan 10 and the ultraviolet lamp 12, a counter 15 for counting the working times of the fan 10 and a warning lamp 16. The effective use times of the cleaning liquid are set through the controller, for example, 20 times, and when the fan 10 works for 20 times, the warning lamp 16 gives an alarm to remind a user of replacement.
The working principle of the invention is as follows:
when nucleic acid is detected, the roller shutter door 4 is closed, a sealed space is formed in the device shell 2 under the action of the sealing strip 41 and the sealing groove 43, the nucleic acid sample can be effectively prevented from diffusing into the air, the fan 10 is opened, the nucleic acid sample in the device shell 2 enters the dissolving box 7 through the air inlet 9, the air outlet pipe 11 and the air inlet head 71 in sequence, and the nucleic acid sample is dissolved through the cleaning solution.
Dissolve box 7 and can install in mounting groove 6 fast through the wedge-shaped face 62 and the compression spring 64 of grip block 61, the fixed position that box 7 will be dissolved to rethread grip block 61, directly take off when the washing liquid is invalid can, be convenient for change the washing liquid.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (5)

1.一种便携式避免核酸检测气溶胶污染的装置，其包括装置壳体(2)，所述装置壳体(2)为中空结构，其安装在放置台(1)上，其内部用于放置核酸检测的检测仪(3)，其特征在于：1. A portable device for avoiding nucleic acid detection aerosol pollution, comprising a device housing (2), wherein the device housing (2) is a hollow structure, which is installed on a placing table (1), and its interior is used for placing A detector (3) for nucleic acid detection, characterized in that: 所述装置壳体(2)的前端设有卷帘门(4)，其左端开设有观察窗(5)，其右端设置有安装槽(6)，溶解盒(7)可拆卸安装在安装槽(6)内，所述溶解盒(7)用于盛放溶解气溶胶的清洗液，其上端设置有进气头(71)，所述装置壳体(2)的上方设置有隔板(8)，所述隔板(8)的中心处开设有进风口(9)，其下端安装有紫外灯(12)，所述隔板(8)与装置壳体(2)形成的空间内安装有风机(10)且与出风管(11)相连通，所述出风管(11)通过连接软管与进气头(71)相连接；The front end of the device casing (2) is provided with a rolling shutter door (4), the left end is provided with an observation window (5), the right end is provided with a mounting groove (6), and the dissolving box (7) is detachably mounted in the mounting groove (6). ), the dissolving box (7) is used to hold the cleaning solution for dissolving aerosols, the upper end of which is provided with an air inlet head (71), and the upper part of the device housing (2) is provided with a partition (8), The center of the partition plate (8) is provided with an air inlet (9), a UV lamp (12) is installed at the lower end thereof, and a fan (9) is installed in the space formed by the partition plate (8) and the device housing (2). 10) and communicated with the air outlet pipe (11), the air outlet pipe (11) is connected with the air inlet head (71) through a connecting hose; 所述安装槽(6)的前后两端通过第二滑槽(63)滑动安装有夹持块(61)，所述夹持块(61)靠近溶解盒(7)的一端设置有楔形面(62)，其另一端与第二滑槽(63)底部之间固定安装有压缩弹簧(64)。The front and rear ends of the installation groove (6) are slidably installed with a clamping block (61) through the second chute (63), and one end of the clamping block (61) close to the dissolution box (7) is provided with a wedge-shaped surface ( 62), a compression spring (64) is fixedly installed between the other end and the bottom of the second chute (63). 2.根据权利要求1所述的一种便携式避免核酸检测气溶胶污染的装置，其特征在于：所述卷帘门(4)的下端和左右两端设置有密封条(41)，所述卷帘门(4)的左右两端滑动安装在第一滑槽(42)内，所述装置壳体(2)的下端设有密封槽(43)，位于卷帘门(4)下端的密封条(41)与密封槽(43)密封连接。2. A portable device for avoiding nucleic acid detection aerosol pollution according to claim 1, characterized in that: the lower end and the left and right ends of the rolling shutter door (4) are provided with sealing strips (41), and the rolling shutter door (4) is provided with a sealing strip (41). ) is slidably installed in the first chute (42), the lower end of the device casing (2) is provided with a sealing groove (43), and the sealing strip (41) and the sealing groove are located at the lower end of the rolling shutter door (4). (43) Sealed connection. 3.根据权利要求1所述的一种便携式避免核酸检测气溶胶污染的装置，其特征在于：所述连接软管的两端固定安装有密封连接头。3 . The portable device for avoiding nucleic acid detection aerosol pollution according to claim 1 , wherein the two ends of the connecting hose are fixedly installed with sealed connectors. 4 . 4.根据权利要求1所述的一种便携式避免核酸检测气溶胶污染的装置，其特征在于：所述装置壳体(2)上设置有控制面板(13)，所述控制面板(13)包括用于控制风机(10)和紫外灯(12)控制开关(14)、用于统计风机(10)工作次数的计数器(15)和警示灯(16)。4. A portable device for avoiding nucleic acid detection aerosol pollution according to claim 1, characterized in that: the device casing (2) is provided with a control panel (13), and the control panel (13) comprises A control switch (14) for controlling the fan (10) and the ultraviolet lamp (12), a counter (15) and a warning light (16) for counting the working times of the fan (10). 5.根据权利要求1所述的一种便携式避免核酸检测气溶胶污染的装置，其特征在于：所述夹持块(61)靠近压缩弹簧(64)的一端中心处固定有导柱(65)，所述导柱(65)滑动安装在导向槽(66)内，所述导向槽(66)设置在第二滑槽(63)远离溶解盒(7)的一端。5. A portable device for avoiding nucleic acid detection aerosol pollution according to claim 1, wherein a guide post (65) is fixed at the center of one end of the clamping block (61) close to the compression spring (64). , the guide post (65) is slidably installed in the guide groove (66), and the guide groove (66) is arranged at one end of the second chute (63) away from the dissolution box (7).
CN202110379498.7A 2021-04-08 2021-04-08 Portable device for avoiding aerosol pollution of nucleic acid detection Pending CN112899145A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119302332A (en) * 2024-09-18 2025-01-14 浙江山山家食品产业发展有限公司 Bread fermentation process

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Publication number Priority date Publication date Assignee Title
CN101788556A (en) * 2010-03-25 2010-07-28 山东博科生物产业有限公司 Biosafety biochemical analyzer
US20130236903A1 (en) * 2010-11-18 2013-09-12 Bioneer Corporation Automatic necleic acid purification apparatus and method for aerosol-protecting
CN106617769A (en) * 2016-12-05 2017-05-10 广西大学 Bookend capable of automatically clamping
CN206751853U (en) * 2017-05-01 2017-12-15 任碧琼 A kind of full-automatic nucleic acid extraction, amplification integrated apparatus
CN108624491A (en) * 2018-04-18 2018-10-09 江苏猎阵生物科技有限公司 A kind of packaged type PCR Lab
RU2712502C1 (en) * 2019-07-01 2020-01-29 Общество с ограниченной Ответственностью "МИКРОБИОТЕХ" Portable device for aerosol disinfection quality control
CN110820710A (en) * 2019-11-25 2020-02-21 天津大学 Clamp for clamping probe rod to continuously penetrate and pull out probe rod
CN112410204A (en) * 2020-11-30 2021-02-26 中国科学院苏州生物医学工程技术研究所 A fully automatic nucleic acid detection system
CN212749283U (en) * 2020-09-15 2021-03-19 北京赫尔默技术有限公司 Non-contact intelligent nuclear biochemical detection equipment
CN214735779U (en) * 2021-04-08 2021-11-16 苏州唯特锐医疗器械有限公司 Portable device for avoiding aerosol pollution of nucleic acid detection

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101788556A (en) * 2010-03-25 2010-07-28 山东博科生物产业有限公司 Biosafety biochemical analyzer
US20130236903A1 (en) * 2010-11-18 2013-09-12 Bioneer Corporation Automatic necleic acid purification apparatus and method for aerosol-protecting
CN106617769A (en) * 2016-12-05 2017-05-10 广西大学 Bookend capable of automatically clamping
CN206751853U (en) * 2017-05-01 2017-12-15 任碧琼 A kind of full-automatic nucleic acid extraction, amplification integrated apparatus
CN108624491A (en) * 2018-04-18 2018-10-09 江苏猎阵生物科技有限公司 A kind of packaged type PCR Lab
RU2712502C1 (en) * 2019-07-01 2020-01-29 Общество с ограниченной Ответственностью "МИКРОБИОТЕХ" Portable device for aerosol disinfection quality control
CN110820710A (en) * 2019-11-25 2020-02-21 天津大学 Clamp for clamping probe rod to continuously penetrate and pull out probe rod
CN212749283U (en) * 2020-09-15 2021-03-19 北京赫尔默技术有限公司 Non-contact intelligent nuclear biochemical detection equipment
CN112410204A (en) * 2020-11-30 2021-02-26 中国科学院苏州生物医学工程技术研究所 A fully automatic nucleic acid detection system
CN214735779U (en) * 2021-04-08 2021-11-16 苏州唯特锐医疗器械有限公司 Portable device for avoiding aerosol pollution of nucleic acid detection

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119302332A (en) * 2024-09-18 2025-01-14 浙江山山家食品产业发展有限公司 Bread fermentation process

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Application publication date: 20210604