CN112827396A - A raw materials mixing arrangement for cell culture medium - Google Patents
A raw materials mixing arrangement for cell culture medium Download PDFInfo
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- CN112827396A CN112827396A CN202110079696.1A CN202110079696A CN112827396A CN 112827396 A CN112827396 A CN 112827396A CN 202110079696 A CN202110079696 A CN 202110079696A CN 112827396 A CN112827396 A CN 112827396A
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- valve pipe
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
- B01F27/90—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with paddles or arms
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/10—Maintenance of mixers
- B01F35/12—Maintenance of mixers using mechanical means
- B01F35/123—Maintenance of mixers using mechanical means using scrapers for cleaning mixers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/90—Heating or cooling systems
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/001—Drying-air generating units, e.g. movable, independent of drying enclosure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/90—Heating or cooling systems
- B01F2035/99—Heating
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/44—Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Mixers Of The Rotary Stirring Type (AREA)
Abstract
The invention relates to the technical field of mixing devices, in particular to a raw material mixing device for a cell culture medium, which comprises a mixing barrel, wherein a protective frame is arranged on the outer wall of the mixing barrel, a mounting frame is arranged on the surface of the protective frame, an axial flow fan is arranged inside the mounting frame, a gas diffusion valve pipe is inserted into the surface of the protective frame, a mounting opening is formed in the surface of the protective frame, a fixing frame is inserted into the mounting opening, a heating pipe is arranged inside the fixing frame, a metal screen plate is arranged at the notch of the fixing frame, and the fixing frame is fixed on the surface of the fixing plate; the beneficial effects are that: according to the raw material mixing device for the cell culture medium, provided by the invention, the surfaces of the driving rollers are additionally provided with the multiple groups of partition plates, the partition plates are matched with the sleeve plates to partition the interior of the mixing barrel, and the raw materials can be independently placed between every two adjacent partition plates, namely the materials in each partition bin body can be different, so that the materials are overturned in the mixing barrel to realize material mixing, and the multiple groups of materials are simultaneously mixed in the mixing barrel.
Description
Technical Field
The invention relates to the technical field of mixing devices, in particular to a raw material mixing device for a cell culture medium.
Background
The cell culture medium is not only a basic substance for supplying cell nutrition and promoting cell reproduction in the cultured cells, but also a living environment for the growth and the reproduction of the cultured cells; when the cell culture medium is prepared, raw materials need to be mixed firstly, only one group of culture medium can be mixed by the traditional mixing equipment at a time, and when a plurality of groups of culture medium raw materials are mixed, the raw materials need to be mixed in sequence, so that the production efficiency is influenced; and the moisture caking phenomenon is easy to occur when the culture medium raw materials are mixed.
Disclosure of Invention
The present invention has been made to solve the above-mentioned problems occurring in the prior art, and an object of the present invention is to provide a raw material mixing apparatus for a cell culture medium.
In order to achieve the purpose, the invention provides the following technical scheme: a raw material mixing device for a cell culture medium comprises a mixing barrel, wherein a protective frame is arranged on the outer wall of the mixing barrel, a mounting frame is arranged on the surface of the protective frame, an axial flow fan is arranged inside the mounting frame, a gas diffusion valve pipe is inserted into the surface of the protective frame, a mounting port is formed in the surface of the protective frame, a fixing frame is inserted into the mounting port, a heating pipe is arranged inside the fixing frame, a metal mesh plate is arranged at the notch of the fixing frame, the fixing frame is fixed on the surface of a fixing plate, a sealing ring is sleeved outside the fixing frame, a sliding plate is arranged on the inner wall of the mixing barrel, a gas injection valve pipe is inserted into the surface of the mixing barrel, the gas injection valve pipe penetrates through the sliding plate, a backflow valve pipe is inserted into the top surface of the mixing barrel, the other end of the backflow valve pipe is inserted into the surface of the protective frame, a, the surface of the sealing cover is provided with a pressure relief valve pipe, a driving shaft is arranged in the mixing cylinder, a separation plate is arranged on the surface of the driving shaft, a sleeve plate is sleeved on the end part of the separation plate, a closing ring is sleeved on the end part of the separation plate and fixed on the inner wall of the sleeve plate, a butt joint slot is arranged on the surface of the separation plate, a guide post is inserted in the butt joint slot and fixed on the inner wall of the sleeve plate, a spring is sleeved on the outer side of the guide post, a scraper is arranged at the end part of the sleeve plate, a blanking frame is inserted on the bottom surface of the mixing cylinder, a baffle is inserted in the top opening of the blanking frame, a buckle plate is arranged on the bottom surface of the baffle, a traction post is arranged on the inner wall of the blanking frame, the other end of the traction post is fixed on the outer wall of the protective cylinder, an electric hydraulic, the bottom surface of the mixing cylinder is provided with a bracket.
Preferably, the mixing drum is the cylinder structure, and the protection frame is convex frame structure, and the protection frame is provided with two sets ofly, and two sets of protection frames are square frame structure about mixing drum symmetric distribution, mounting bracket, and the mounting bracket is placed in the middle at the outer wall of protection frame.
Preferably, the installing port is square cylinder structure, and the installing port is provided with a plurality ofly, and a plurality of installing ports are arranged along the circular arc surface equidimension such as protection frame equidistance and are distributed, and the mount is square frame structure, and the metal mesh board is square plate structure, and the surface of fixed plate is provided with the screw, and the screw passes through behind the fixed plate spiro union at the outer wall of protection frame.
Preferably, the material sliding plates are of circular arc-shaped plate structures, the material sliding plates are provided with a plurality of material sliding plates, the material sliding plates are distributed in a cross-shaped arrangement mode, the backflow valve pipe is of an L-shaped circular pipe structure, and check valves are arranged on the surfaces of the backflow valve pipe, the gas injection valve pipe, the pressure release valve pipe and the gas diffusion valve pipe.
Preferably, the inner wall of hopper is provided with the internal thread, and the closing cap is "protruding" font plectane structure, and the surface of closing cap is provided with the external screw thread, and the top surface of closing cap is provided with the handle pole, and the handle pole is "L" shape structure, and the handle pole is provided with a plurality ofly, and a plurality of handle poles are "ten" font and arrange the distribution.
Preferably, the division board is "T" font platelike structure, the division board is provided with a plurality ofly, the contained angle is sixty degrees between two adjacent division boards, the lagging is square frame structure, the binding ring is annular platelike structure, butt joint slot and guide post all are the cylinder structure, the butt joint slot is provided with a plurality ofly, a plurality of butt joint slots are arranged along the long limit of the tip plate body of division board and are distributed, the scraper blade is convex platelike structure, the surface of scraper blade is provided with the rubber scraping wings, the rubber scraping wings is provided with two, be provided with the brush hair between two rubber scraping wings, the brush hair bonds on the surface of scraper blade.
Preferably, the blanking frame is of a convex frame structure, the baffle is of a square plate structure, the top surface of the baffle is of a circular arc curved surface, and the buckle is of a square frame structure.
Compared with the prior art, the invention has the beneficial effects that: the invention has reasonable structure and strong functionality, and has the following advantages:
1. according to the raw material mixing device for the cell culture medium, provided by the invention, multiple groups of partition plates are additionally arranged on the surface of the driving roller, the partition plates are matched with the sleeve plates to partition the interior of the mixing cylinder, and raw materials can be independently placed between every two adjacent partition plates, namely the materials in each partition cabin body can be different, so that the materials are turned over in the mixing cylinder to realize material mixing, and thus, multiple groups of materials are simultaneously mixed in the mixing cylinder;
2. according to the raw material mixing device for the cell culture medium, the guide post is additionally arranged between the partition plate and the sleeve plate for traction, and the spring is sleeved outside the guide post, so that the sleeve plate elastically slides outside the partition plate, a scraper is enabled to be attached to the inner wall of the mixing cylinder in use, and residual materials on the inner wall of the mixing cylinder are swept down by the scraper;
3. according to the raw material mixing device for the cell culture medium, the protection frame is additionally arranged on the outer side of the mixing cylinder, the heating pipe arranged in the protection frame heats air injected by the air dispersing valve pipe, and the heated air is uniformly blown into the mixing cylinder through the air injection valve pipe to dry materials, so that the drying of the materials is ensured, and the caking phenomenon of the materials is reduced.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the structure of the blanking frame of the present invention;
FIG. 3 is an enlarged view of the structure at A in FIG. 1;
fig. 4 is an enlarged schematic view of the structure at B in fig. 1.
In the figure: the device comprises a mixing cylinder 1, a protective frame 2, a mounting frame 3, an axial flow fan 4, an air diffusing valve pipe 5, a mounting port 6, a fixing frame 7, a heating pipe 8, a metal mesh plate 9, a fixing plate 10, a sealing ring 11, a material sliding plate 12, an air injection valve pipe 13, a backflow valve pipe 14, a hopper 15, a sealing cover 16, a pressure relief valve pipe 17, a driving shaft 18, a separation plate 19, a sleeve plate 20, a closing ring 21, a butt joint slot 22, a guide post 23, a spring 24, a scraper 25, a blanking frame 26, a baffle plate 27, a pinch plate 28, an electric hydraulic cylinder 29, a protective cylinder 30, a drawing post 31 and a support 32.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1 to 4, the present invention provides a technical solution: a raw material mixing device for a cell culture medium comprises a mixing barrel 1, wherein a protective frame 2 is arranged on the outer wall of the mixing barrel 1, a mounting frame 3 is arranged on the surface of the protective frame 2, the mixing barrel 1 is of a cylindrical structure, the protective frame 2 is of a circular arc frame structure, two groups of protective frames 2 are arranged on the protective frame 2, the two groups of protective frames 2 are symmetrically distributed around the mixing barrel 1, the mounting frame 3 is of a square frame structure, the mounting frame 3 is arranged in the middle of the outer wall of the protective frame 2, an axial flow fan 4 is arranged inside the mounting frame 3, an air diffusion valve pipe 5 is inserted into the surface of the protective frame 2, a mounting port 6 is formed in the surface of the protective frame 2, a fixing frame 7 is inserted into the mounting port 6, a heating pipe 8 is arranged inside the fixing frame 7, a metal mesh plate 9 is arranged at the notch of the fixing frame 7, the fixing frame 7, the mounting openings 6 are arranged in a plurality of numbers, the mounting openings 6 are arranged in equal size along the arc surface of the protection frame 2 at equal intervals, the fixing frame 7 is in a square frame structure, the metal mesh plate 9 is in a square plate structure, the surface of the fixing plate 10 is provided with screws, and the screws penetrate through the fixing plate 10 and then are screwed on the outer wall of the protection frame 2;
the inner wall of the mixing cylinder 1 is provided with a sliding material plate 12, the surface of the mixing cylinder 1 is inserted with a gas injection valve pipe 13, the gas injection valve pipe 13 penetrates through the sliding material plate 12, the top surface of the mixing cylinder 1 is inserted with a backflow valve pipe 14, the other end of the backflow valve pipe 14 is inserted on the surface of the protective frame 2, the top surface of the mixing cylinder 1 is inserted with a hopper 15, the top end of the hopper 15 is inserted with a sealing cover 16, the inner wall of the hopper 15 is provided with internal threads, the sealing cover 16 is in a convex circular plate structure, the surface of the sealing cover 16 is provided with external threads, the top surface of the sealing cover 16 is provided with a handle rod, the handle rods are in an L-shaped structure, the handle rods are in a plurality of cross-shaped arrangement distribution, the surface of the sealing cover 16 is provided with a pressure relief valve pipe 17, the sliding material plate 12 is in an arc-shaped plate structure, the sliding material plate 12 is in a plurality of cross-shaped arrangement distribution, the backflow valve, check valves are arranged on the surfaces of the backflow valve pipe 14, the gas injection valve pipe 13, the pressure release valve pipe 17 and the air dispersing valve pipe 5;
the mixing cylinder 1 is internally provided with a driving shaft 18, the surface of the driving shaft 18 is provided with a partition plate 19, the end part of the partition plate 19 is sleeved with a sleeve plate 20, the end part of the partition plate 19 is sleeved with a closing ring 21, the closing ring 21 is fixed on the inner wall of the sleeve plate 20, the surface of the partition plate 19 is provided with a butt joint slot 22, the inside of the butt joint slot 22 is inserted with a guide post 23, the guide post 23 is fixed on the inner wall of the sleeve plate 20, the outer side of the guide post 23 is sleeved with a spring 24, the end part of the sleeve plate 20 is provided with a scraper 25, the partition plate 19 is of a T-shaped plate structure, the partition plates 19 are provided with a plurality of partition plates 19, the included angle between two adjacent partition plates 19 is sixty degrees, the sleeve plate 20 is of a square frame structure, the closing ring 21 is of an annular plate structure, the butt joint slot 22 and the guide post 23 are, the scraper 25 is of an arc-shaped plate structure, two rubber material pushing plates are arranged on the surface of the scraper 25, bristles are arranged between the two rubber material pushing plates and are bonded to the surface of the scraper 25, a blanking frame 26 is inserted into the bottom surface of the mixing drum 1, a baffle 27 is inserted into an opening at the top of the blanking frame 26, a buckle plate 28 is arranged on the bottom surface of the baffle 27, the blanking frame 26 is of a convex frame structure, the baffle 27 is of a square plate structure, the top surface of the baffle 27 is of an arc-shaped curved surface, the buckle plate 28 is of a square frame structure, a traction column 31 is arranged on the inner wall of the blanking frame 26, the other end of the traction column 31 is fixed on the outer wall of the protective drum 30, an electric hydraulic cylinder 29 is arranged inside the protective drum 30, a piston rod of the electric hydraulic cylinder 29 is fixed on.
The working principle is as follows: when the device is in actual use, materials are put between two adjacent separation plates 19 through the hopper 15, the separation plates 19 and the sleeve plates 20 form a separation structure, the materials are independently stored between the two adjacent separation structures, the position of the separation structure is switched by rotating the driving shaft 18, the materials are overturned and mixed when the materials rotate along with the adjacent separation structures, air extracted by the axial flow fan 4 is injected into the protection frame 2 through the air diffusing valve pipe 5, the heating pipe 8 heats the air inside the protection frame 2, the heated air is injected into the mixing cylinder 1 through the air injection valve pipe 13 to dry the materials, one part of high-pressure gas is diffused through the pressure release valve pipe 17, the other part of high-pressure gas is injected into the protection frame 2 through the return valve pipe 14 to realize the heat preservation and pressurization of the gas inside the protection frame 2, the scraper 25 scrapes the materials on the inner wall of the mixing cylinder 1 and the surface of the sliding plate 12, and the piston rod of the electric hydraulic, until the buckle plate 28 is buckled on the top surface of the protective cylinder 30, the falling materials in the mixing cylinder 1 fall on the top surface of the baffle plate 27 and are dispersed to both sides and discharged along the blanking frame 26.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (7)
1. A raw material mixing device for cell culture media, comprising a mixing drum (1), characterized in that: the outer wall of the mixing cylinder (1) is provided with a protective frame (2), the surface of the protective frame (2) is provided with a mounting frame (3), an axial flow fan (4) is arranged inside the mounting frame (3), an air diffusing valve pipe (5) is inserted into the surface of the protective frame (2), a mounting port (6) is formed in the surface of the protective frame (2), a fixing frame (7) is inserted into the mounting port (6), a heating pipe (8) is arranged inside the fixing frame (7), a metal mesh plate (9) is arranged at the notch of the fixing frame (7), the fixing frame (7) is fixed on the surface of a fixing plate (10), a sealing ring (11) is sleeved outside the fixing frame (7), the inner wall of the mixing cylinder (1) is provided with a material sliding plate (12), an air injection valve pipe (13) is inserted into the surface of the mixing cylinder (1), and the air injection valve pipe (13) penetrates through the, the top surface of the mixing cylinder (1) is inserted with a backflow valve pipe (14), the other end of the backflow valve pipe (14) is inserted on the surface of the protection frame (2), the top surface of the mixing cylinder (1) is inserted with a hopper (15), the top end of the hopper (15) is inserted with a sealing cover (16), the surface of the sealing cover (16) is provided with a pressure relief valve pipe (17), the inside of the mixing cylinder (1) is provided with a driving shaft (18), the surface of the driving shaft (18) is provided with a separation plate (19), the end part of the separation plate (19) is sleeved with a sleeve plate (20), the end part of the separation plate (19) is sleeved with a receiving ring (21), the receiving ring (21) is fixed on the inner wall of the sleeve plate (20), the surface of the separation plate (19) is provided with a butt joint slot (22), the inside of the butt joint slot (22) is inserted with a guide column (23), and the guide column (23), the outer side of the guide post (23) is sleeved with a spring (24), the end part of the sleeve plate (20) is provided with a scraper (25), the bottom surface of the mixing cylinder (1) is spliced with a blanking frame (26), the top opening of the blanking frame (26) is spliced with a baffle (27), the bottom surface of the baffle (27) is provided with a buckle plate (28), the inner wall of the blanking frame (26) is provided with a traction post (31), the other end of the traction post (31) is fixed on the outer wall of the protective cylinder (30), the inner part of the protective cylinder (30) is provided with an electric hydraulic cylinder (29), a piston rod of the electric hydraulic cylinder (29) is fixed on the bottom surface of the baffle (27), and the bottom surface of the mixing cylinder (1) is provided with a support.
2. A feedstock mixing apparatus for cell culture media according to claim 1, wherein: mixing drum (1) is the cylinder structure, and protection frame (2) are convex frame structure, and protection frame (2) are provided with two sets ofly, and two sets of protection frame (2) are square frame structure about mixing drum (1) symmetric distribution, mounting bracket (3), and mounting bracket (3) are between two parties at the outer wall of protection frame (2).
3. A feedstock mixing apparatus for cell culture media according to claim 1, wherein: installing port (6) are square cylinder structure, and installing port (6) are provided with a plurality ofly, and a plurality of installing ports (6) are arranged along the circular arc surface equidimension such as protection frame (2) equidistance and are distributed, and mount (7) are square frame structure, and metal mesh plate (9) are square platelike structure, and the surface of fixed plate (10) is provided with the screw, and the screw passes through behind fixed plate (10) spiro union at the outer wall of protection frame (2).
4. A feedstock mixing apparatus for cell culture media according to claim 1, wherein: the material sliding plates (12) are of circular arc-shaped plate structures, a plurality of material sliding plates (12) are arranged, the material sliding plates (12) are distributed in a cross shape, the backflow valve pipe (14) is of an L-shaped circular pipe structure, and check valves are arranged on the surfaces of the backflow valve pipe (14), the gas injection valve pipe (13), the pressure release valve pipe (17) and the air diffusion valve pipe (5).
5. A feedstock mixing apparatus for cell culture media according to claim 1, wherein: the inner wall of hopper (15) is provided with the internal thread, and closing cap (16) are "protruding" font plectane structure, and the surface of closing cap (16) is provided with the external screw thread, and the top surface of closing cap (16) is provided with the handle pole, and the handle pole is "L" shape structure, and the handle pole is provided with a plurality ofly, and a plurality of handle poles are "ten" font and arrange the distribution.
6. A feedstock mixing apparatus for cell culture media according to claim 1, wherein: division board (19) are "T" font platelike structure, division board (19) are provided with a plurality ofly, contained angle is sixty degrees between two adjacent division boards (19), lagging (20) are square frame structure, closing ring (21) are annular platelike structure, butt joint slot (22) and guide post (23) all are circular cylinder structure, butt joint slot (22) are provided with a plurality ofly, a plurality of butt joint slot (22) are arranged along the long limit of the tip plate body of division board (19) and are distributed, scraper blade (25) are convex platelike structure, the surface of scraper blade (25) is provided with the rubber scraping wings, the rubber scraping wings is provided with two, be provided with the brush hair between two rubber scraping wings, the brush hair bonds in the surface of scraper blade (25).
7. A feedstock mixing apparatus for cell culture media according to claim 1, wherein: the blanking frame (26) is of a convex frame structure, the baffle (27) is of a square plate structure, the top surface of the baffle (27) is of a circular arc curved surface, and the buckle plate (28) is of a square frame structure.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202110079696.1A CN112827396B (en) | 2021-01-21 | 2021-01-21 | A raw materials mixing arrangement for cell culture medium |
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| CN202110079696.1A CN112827396B (en) | 2021-01-21 | 2021-01-21 | A raw materials mixing arrangement for cell culture medium |
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| CN112827396B CN112827396B (en) | 2022-11-29 |
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Effective date of registration: 20221108 Address after: No. 60, Beijing Middle Road, Yantai Development Zone, Shandong Province, 264000 Applicant after: Yantai Saipu Biotechnology Co.,Ltd. Address before: Guizhou Institute of engineering application technology, No.1, Xueyuan Road, qixingguan District, Bijie City, Guizhou Province Applicant before: Wang Liyou |
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