CN1124653A - Natural medicine for resisting pyloric Helicobacterium - Google Patents
Natural medicine for resisting pyloric Helicobacterium Download PDFInfo
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- CN1124653A CN1124653A CN 95110700 CN95110700A CN1124653A CN 1124653 A CN1124653 A CN 1124653A CN 95110700 CN95110700 CN 95110700 CN 95110700 A CN95110700 A CN 95110700A CN 1124653 A CN1124653 A CN 1124653A
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Abstract
The medicine containing one or several of active components extracted from natural plants can serve to kill pyloric helicobacteria with high effect.
Description
The present invention relates to natural medicine for resisting helicobacter pylori.
In 1982, Warren and Marshall discovered that gastric disease is an infectious disease, and the causative bacteria of gastric cancer and the transmission of gastric disease is Helicobacter Pylori (HP), which is primarily an oral infection from person to person. The bacterium is parasitic in oral cavity and gastric mucosa of human, especially in teeth slit, and enters stomach with saliva, resulting in occurrence and development of gastropathy and gastric cancer. Statistically, the infection rate of children aged 5 years reaches 50%, and the infection rate of adults reaches 70% -90%, and the world health organization has classified the infection rate as the first grade of grade 5 carcinogen together with hepatitis B virus and hepatitis C virus in view of the great harm of helicobacter pylori. (national journal of the people, 11 months and 22 days, 7 th edition 1994). Although the research on treating the hot tide of helicobacter pylori infection is started in all countries all over the world at present, all the used medicines are antibiotics and chemical synthetic products, have large toxic and side effects, and have serious adverse reactions on human organs such as liver, kidney, stomach, intestine, brain and the like.
The invention aims to provide a natural anti-helicobacter pylori medicament with no or little toxic and side effects.
The anti-helicobacter pylori medicament provided by the invention comprises one or more of the following components: 0.001-3% of cinnamaldehyde, 0.001-4% of benzoic acid, 0.001-3% of thymol, 0.001-3% of orange peel oil, 0.0001-5% of cinnamic acid, 0.01-2% of eucalyptol, 0.001-2.5% of camphor, 0.001-3% of clove oil, 0.001-6% of anisic aldehyde, 0.01-5% of ginkgol, 0.001-3% of gossypol, 0.1-2.6% of catechol, 0.01-3% of anise oil, 0.1-5% of clove basil oil, 0.1-3.2% of fennel oil, 0.01-2.6% of cardamom oil, 0.1-3.3% of rose oil, 0.1-3.1% of orange flower oil, 0.01-3.5% of perilla oil, 0.01-4.5% of rosemary oil, 0.2-3.6% of grapefruit oil, 0.01-3% of lysimachia foenum-2, 0.01-2.1% of azalea oil, 0.01-2.1% of theobromine, 0.01-2.1%, 2.1-2.1% of theobromine, 0.1%, 2.01-2.1% of theobromine, 2.1.2%, 2.1-2.5%, 2.1%, 2.1.1.2.1% of theobromine, 0.01 to 3.1 percent of berberine, 0.01 to 2.8 percent of toad, 0.001 to 2.6 percent of menthol, 0.01 to 4 percent of zanthoxylum alkaloid, 0.001 to 3 percent of oleanolic acid, 0.02 to 3 percent of pepper oil, 0.01 to 4.5 percent of paeonol, 0.01 to 3.5 percent of piperine, 0.01 to 4 percent of hop oil, 0.01 to 3.8 percent of anethole, 0.001 to 2.5 percent of bay oil, 0.001 to 2.8 percent of kumquat essential oil, 0.001 to 2.2 percent of onion essential oil, 0.001 to 3.8 percent of garlicin and 0.001 to 2.2 percent of ginger oil.
Before the solid medicine in the above-mentioned components is added, it is ground into superfine powder which is passed through 200 meshes sieve by adopting colloid mill so as to increase specific surface of medicine, and can make it have large contact surface with helicobacter pylori in oral cavity and stomach, and can raise bactericidal power of medicine so as to reduce dosage of medicine.
The ingredients of the medicine used by the invention are generally compounded to reduce the unpleasant smell and the uncomfortable taste of the medicine. And can block the biological metabolic process of helicobacter pylori (such as destroying the biological membrane of helicobacter pylori, combining with the enzyme of the helicobacter pylori to make it lose activity, interfering the synthesis of deoxyribonucleic acid of the helicobacter pylori, etc.) in many aspects, thereby achieving the effect of quickly killing the helicobacter pylori.
The various natural medicines of the invention can be classified into five types of aromatic volatile type, alkaloid type, phenol type, acid type and animal type according to the characteristics of the physicochemical properties of the medicines. The preparation method comprises the following steps:
1. aromatic volatile drugs: cinnamic aldehyde, eucalyptol, camphor, orange peel oil, anise aldehyde, clove oil, star anise oil, clove basil oil, fennel oil, cardamom oil, rose oil, citrus aurantium flower oil, perilla oil, rosemary oil, grapefruit oil, celery seed oil, pine oil, menthol, pepper oil, anethole, bay oil, kumquat essential oil, onion essential oil, garlicin, ginger oil, and hop oil. Preparation method thereofThe method comprises the following steps: crude drug → cut up → steam distillation 。
2. Alkaloid drugs: leonurine, nitidine, solanine, theobromine, theophylline, lycopersicin, berberine, zanthoxyline and piperine. The preparation method comprises the following steps: crude drug →
3. Phenolic drugs: catechol, thymol, gossypol, and paeonol. The preparation method comprises the following steps: 。
4. acid drugs: benzoic acid, cinnamic acid, oleanolic acid. The preparation method comprises the following steps:
5. animal drugs: zibethum, Moschus, and Bufo siccus. The preparation method comprises the following steps: directly taking off medicinal organs from medicinal animals, drying in the shade, and adding into medicine.
Clinical experiments showed that the present inventors performed Helicobacter Pylori (HP) assay for 1000 cases, wherein, before use, 908 cases of HP-positive cases, and after use, all oral HP turned negative. The invention can kill HP in 3-5 min, with 100% efficiency.
Because people can easily infect helicobacter pylori in daily life, the oral cavity and the stomach cannot be kept from being infected heavily for a long time by one-time sterilization. In this regard, frequent sterilization of the oral cavity and stomach should be used as a means for preventing and treating diseases caused by helicobacter pylori.
Therefore, one or more natural medicines for resisting the helicobacter pylori are added into daily oral hygiene products, foods or beverages of people, so that the method is convenient and can keep the oral cavity and the stomach from being infected by the helicobacter pylori for a long time.
Example 1:
0.5% of cinnamic aldehyde
The first experiment method comprises the following steps: adding 0.5% cinnamaldehyde into BrookfieldThe mixture is dissolved to the concentration of 600mg/ml,and 109Two strains of helicobacter pylori (NCTC11637 strain and CAPMN45 strain) with individual strain/ml concentration are respectively mixed according to the proportion of 1: 1, the drug action is respectively stopped after 1 minute, 2 minutes, 3 minutes, 4 minutes and 5 minutes, and the two strains are respectively inoculated on a double plate, cultured for three days under the condition of mixed gas environment at 37 ℃, and the survival condition of the bacteria is observed. The control group used distilled water without the antibacterial agent as a parallel control. Before and after the whole experimental process, the adopted bacteria are cultured, and the survival condition of the bacteria is observed.
II, experimental results:
1. both experimental strains survived well throughout the experiment.
2.0.1% of cinnamaldehyde can completely kill two strains of experimental helicobacter pylori within 3 minutes, 4 minutes and 5 minutes. The control group failed to kill both experimental strains of H.pylori within 5 minutes.
Example 2:
0.5% benzoic acid
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.5% benzoic acid can completely kill two experimental strains of helicobacter pylori within 3 minutes, 4 minutes and 5 minutes.
Example 3:
0.6% thymol
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.6% benzoic acid can completely kill two experimental strains of helicobacter pylori within 5 minutes.
Example 4:
0.5% orange peel oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the orange peel oil with the concentration of 0.5 percent can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 5:
0.8% cinnamic acid
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.8% cinnamic acid can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 6:
0.10% eucalyptol
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the eucalyptol 0.10% can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 7:
0.6% of camphor
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.6% camphor can completely kill two strains of helicobacter pylori for experiments within 5 minutes.
Example 8:
0.5% clove oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.5% clove oil can completely kill two strains of experimental helicobacter pylori within 3 minutes, 4 minutes and 5 minutes.
Example 9:
0.6% anisic aldehyde
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.6 percent anisic aldehyde can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 10:
0.8% of ginkgol
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.8% ginnol can completely kill two experimental helicobacter pylori in 5 minutes.
Example 11:
0.5% gossypol
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.5% gossypol can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 12:
0.9% of catechol
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.9% catechol completely killed two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 13:
0.5% of star anise oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.5 percent star anise oil can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 14:
0.1% Ocimum gratissimum oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.1% clove basil oil can completely kill two strains of experimental helicobacter pylori within 5 minutes.
Example 15:
0.5% Fennel oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.5 percent fennel oil can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 16:
0.6% cardamom oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.6% cardamom oil can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 17:
0.5% Rose oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the rose oil with the concentration of 0.5 percent can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 18:
0.7% Daidai flower oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.7 percent of daidaidai flower oil can completely kill two strains of helicobacter pylori for experiments within 5 minutes.
Example 19:
0.5% perilla oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the perilla oil with the concentration of 0.5 percent can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 20:
0.5% Rosemary oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.5 percent of rosemary oil can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 21:
0.6% grapefruit oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.6% grapefruit oil can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 22:
0.9% civet
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the civet with the concentration of 0.9 percent can completely kill two experimental helicobacter pylori within 5 minutes.
Example 23:
0.3% of musk
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.3 percent musk can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 24:
0.3% farrerol
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.3 percent of farrerol can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 25:
0.5% leonurine
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the leonurine with the concentration of 0.5 percent can completely kill two experimental helicobacter pylori within 3 minutes, 4 minutes and 5 minutes.
Example 26:
0.8% nitidine
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.8% nitidine can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 27:
0.6% of solanine
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.6% solanine can completely kill two strains of experimental helicobacter pylori within 3 minutes, 4 minutes and 5 minutes.
Example 28:
0.3% theobromine
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.3% theobromine can completely kill two experimental helicobacter pylori in 4 minutes and 5 minutes.
Example 29:
0.5% theophylline
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.5% theophylline can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 30:
0.1% of lycopersine
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.1% of the lycopersicin can completely kill two strains of helicobacter pylori for experiments within 5 minutes.
Example 31:
0.6% celery seed oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.6% celery seed oil can completely kill two experimental helicobacter pylori in 3 minutes, 4 minutes and 5 minutes.
Example 32:
0.8% pine oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.8% pine oil can completely kill two strains of helicobacter pylori for experiments within 5 minutes.
Example 33:
0.5% berberine
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.5 percent of berberine can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 34:
0.3% toad
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.3% toad can completely kill two strains of helicobacter pylori for experiments within 5 minutes.
Example 35:
0.8% menthol
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.8 percent of menthol can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 36:
0.9% of zanthoxylum bungeanum alkali
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.9 percent of zanthoxylum bungeanum alkali can completely kill two strains of helicobacter pylori for experiments within 5 minutes.
Example 37:
0.5% oleanolic acid
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.5 percent of oleanolic acid can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 38:
0.9% Pepper oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the pepper oil 0.9% can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 39:
0.6% paeonol
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.6 percent paeonol can completely kill two strains of experimental helicobacter pylori within 3 minutes, 4 minutes and 5 minutes.
Example 40:
0.5% piperine
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.5% piperine can completely kill two strains of experimental helicobacter pylori within 5 minutes.
Example 41:
0.6% hop oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.6% hop oil can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 42:
0.9% anethole
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.9% anethole can completely kill two strains of helicobacter pylori for experiments within 5 minutes.
Example 43:
0.8% of laurel oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.8% laurel oil can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 44:
0.7% of kumquat essential oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.7% kumquat essential oil can completely kill two strains of helicobacter pylori for experiments within 3 minutes, 4 minutes and 5 minutes.
Example 45:
0.5% onion essential oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.5 percent onion essential oil can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 46:
0.8% allicin
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: 0.8% allicin can completely kill two strains of helicobacter pylori for experiments within 5 minutes.
Example 47:
0.5% ginger oil
The first experiment method comprises the following steps: same as in example 1.
II, experimental results: the 0.5% ginger oil can completely kill two strains of helicobacter pylori for experiments within 4 minutes and 5 minutes.
Example 48:
the formula comprises the following components: 0.01% of cinnamaldehyde, 0.03% of eucalyptol, 0.02% of star anise oil, 0.15% of perilla oil, 0.01% of rosemary oil, 0.02% of cardamom oil, 0.15% of clove basil oil, 0.01% of cinnamic acid, 0.01% of ginkgol and the balance of auxiliary agents.
II, an experimental method: the experiment was carried out as described in example 1.
Thirdly, experimental results: two experimental strains of H.pylori were completely killed within 1 minute.
Example 49:
the formula comprises the following components: 0.01 percent of musk, 0.01 percent of leonurine, 0.01 percent of solanine, 0.01 percent of piperine, 0.001 percent of kumquat essential oil, 0.01 percent of ginger oil, 0.001 percent of bay oil, 0.01 percent of paeonol, 0.001 percent of menthol and the balance of auxiliary agents.
II, an experimental method: the experiment was carried out as described in example 1.
Thirdly, experimental results: two experimental strains of H.pylori were completely killed within 1 minute.
Example 50:
the formula comprises the following components: 0.01% of benzoic acid, 0.01% of orange peel oil, 0.01% of camphor, 0.01% of clove oil, 0.001% of anisic aldehyde, 0.01% of gossypol, 0.001% of catechol, 0.01% of rose oil, 0.001% of grapefruit oil and the balance of auxiliary agents.
II, an experimental method: the experiment was carried out as described in example 1.
Thirdly, experimental results: two experimental strains of H.pylori were completely killed within 3 minutes.
Example 51:
the formula comprises the following components: 0.01 percent of civet, 0.01 percent of farrerol, 0.01 percent of nitidine, 0.01 percent of theobromine, 0.001 percent of zanthoxylum bungeanum alkali, 0.01 percent of toad, 0.001 percent of pine oil, 0.01 percent of anethole, 0.001 percent of allicin and the balance of auxiliary agents.
II, an experimental method: the experiment was carried out as described in example 1.
Thirdly, experimental results: two experimental strains of H.pylori were completely killed within 2 minutes.
Claims (6)
1. The natural medicine for resisting helicobacter pylori is characterized in that the natural medicine contains one of the following components:
0.001-3% of cinnamaldehyde, 0.001-4% of benzoic acid, 0.001-3% of thymol, 0.001-3% oforange peel oil, 0.0001-5% of cinnamic acid, 0.01-2% of eucalyptol, 0.01-2.5% of camphor, 0.001-3% of clove oil, 0.001-6% of anisic aldehyde, 0.001-5% of ginkgol, 0.001-3% of gossypol, 0.1-2.6% of catechol, 0.01-3% of anise oil, 0.1-5% of clove basil oil, 0.1-3.2% of fennel oil, 0.01-2.6% of cardamom oil, 0.1-3.3% of rose oil, 0.1-3.1% of orange flower oil, 0.01-3.5% of perilla oil, 0.01-4.5% of rosemary oil, 0.2-3.6% of grapefruit oil, 0.01-3% of lysimachia foenum-2, 0.01-2.1% of azalea oil, 0.01-2.1% of theobromine, 0.01-3.1% of theobromine, 0.01-2.1%, 2.1-2.1% of theobromine, 0.01-2.1%, 2.1% of theobromine, 2.1-2.1%, 2.1.1.5%, 2.1.1% of theobromine, 2.1%, 2, 0.01 to 8.1 percent of berberine, 0.01 to 2.8 percent of toad, 0.001 to 2.6 percent of menthol, 0.01 to 4 percent of zanthoxylum alkaloid, 0.001 to 3 percent of oleanolic acid, 0.02 to 3 percent of pepper oil, 0.01 to 4.5 percent of paeonol, 0.01 to 3.5 percent of piperine, 0.01 to 4 percent of hop oil, 0.01 to 3.8 percent of anethole, 0.001 to 2.5 percent of bay oil, 0.001 to 2.8 percent of kumquat essential oil, 0.001 to 2.2 percent of onion essential oil, 0.001 to 3.8 percent of garlicin and 0.001 to 2.2 percent of ginger oil. The balance of auxiliary agents.
2. The natural medicine for helicobacter pylori according to claim 1, wherein said natural medicine comprises:
0.01% of cinnamaldehyde, 0.03% of eucalyptol, 0.02% of star anise oil, 0.15% of perilla oil, 0.01% of rosemary oil, 0.02% of cardamom oil, 0.15% of clove basil oil, 0.01% of cinnamic acid, 0.01% of ginkgol and the balance of auxiliary agents.
3. The natural medicine for helicobacter pylori according to claim 1, wherein said natural medicine comprises:
0.01 percent of musk, 0.01 percent of leonurine, 0.01 percent of solanine, 0.01 percent of piperine, 0.001 percent of kumquat essential oil, 0.01 percent of ginger oil, 0.001 percent of bay oil, 0.01 percent of paeonol, 0.001 percent of menthol and the balance of auxiliary agents.
4. The natural medicine for helicobacter pylori according to claim 1, wherein said natural medicine comprises:
0.01% of benzoic acid, 0.01% of orange peel oil, 0.01% of camphor, 0.01% of clove oil, 0.001% of anisic aldehyde, 0.01% of gossypol, 0.001% of catechol, 0.01% of rose oil, 0.001% of grapefruit oil and the balance of auxiliary agents.
5. The natural medicine for helicobacter pylori according to claim 1, wherein said natural medicine comprises:
0.01 percent of civet, 0.01 percent of farrerol, 0.01 percent of nitidine, 0.01 percent of theobromine, 0.001 percent of zanthoxylum bungeanum alkali, 0.01 percent of toad, 0.001 percent of pine oil, 0.01 percent of anethole, 0.001 percent of allicin and the balance of auxiliary agents.
6. The natural drug against helicobacter pylori according to any one of claims 1 to 5, which is added to an oral hygiene product, food or drink as an additive.
Priority Applications (1)
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CN 95110700 CN1124653A (en) | 1995-04-05 | 1995-04-05 | Natural medicine for resisting pyloric Helicobacterium |
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CN 95110700 CN1124653A (en) | 1995-04-05 | 1995-04-05 | Natural medicine for resisting pyloric Helicobacterium |
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009119667A1 (en) * | 2008-03-27 | 2009-10-01 | 国立大学法人広島大学 | Helicobacter pylori GROWTH INHIBITOR AND METHOD FOR PRODUCTION THEREOF |
CN101119704B (en) * | 2004-12-21 | 2011-08-17 | 高露洁-棕榄公司 | Oral care malodor composition |
CN105147650A (en) * | 2015-10-14 | 2015-12-16 | 上海中医药大学 | Medical application of paeonol |
JP2016000709A (en) * | 2014-06-12 | 2016-01-07 | 仲邑 羅 | Method for inhibiting helicobacter pylori |
CN109172555A (en) * | 2018-10-30 | 2019-01-11 | 武汉卫无忧生物科技有限公司 | Purposes of the Paeonol in the drug for preparing anti-helicobacter pylori |
CN109248103A (en) * | 2018-10-30 | 2019-01-22 | 武汉卫无忧生物科技有限公司 | A kind of dental care products of anti-helicobacter pylori |
CN109248168A (en) * | 2018-10-30 | 2019-01-22 | 武汉卫无忧生物科技有限公司 | Purposes of the oleanolic acid in the drug for preparing anti-helicobacter pylori |
CN109288825A (en) * | 2018-10-30 | 2019-02-01 | 武汉卫无忧生物科技有限公司 | A kind of dental care products of anti-helicobacter pylori |
-
1995
- 1995-04-05 CN CN 95110700 patent/CN1124653A/en active Pending
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101119704B (en) * | 2004-12-21 | 2011-08-17 | 高露洁-棕榄公司 | Oral care malodor composition |
WO2009119667A1 (en) * | 2008-03-27 | 2009-10-01 | 国立大学法人広島大学 | Helicobacter pylori GROWTH INHIBITOR AND METHOD FOR PRODUCTION THEREOF |
JP2016000709A (en) * | 2014-06-12 | 2016-01-07 | 仲邑 羅 | Method for inhibiting helicobacter pylori |
CN105147650A (en) * | 2015-10-14 | 2015-12-16 | 上海中医药大学 | Medical application of paeonol |
CN109172555A (en) * | 2018-10-30 | 2019-01-11 | 武汉卫无忧生物科技有限公司 | Purposes of the Paeonol in the drug for preparing anti-helicobacter pylori |
CN109248103A (en) * | 2018-10-30 | 2019-01-22 | 武汉卫无忧生物科技有限公司 | A kind of dental care products of anti-helicobacter pylori |
CN109248168A (en) * | 2018-10-30 | 2019-01-22 | 武汉卫无忧生物科技有限公司 | Purposes of the oleanolic acid in the drug for preparing anti-helicobacter pylori |
CN109288825A (en) * | 2018-10-30 | 2019-02-01 | 武汉卫无忧生物科技有限公司 | A kind of dental care products of anti-helicobacter pylori |
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