Disclosure of Invention
The invention aims to provide an equivalent inspiration instrument so as to eliminate puncture errors caused by breathing when CT guidance is used for interventional therapy or puncture biopsy.
The technical scheme of the invention is as follows.
In a first aspect, the present invention provides an equivalent inspiration meter comprising: an oxygen source, a throttle valve, a valve set, a flexible bladder, a rigid container, an inflator, a mask assembly, and a system controller; it is characterized in that the preparation method is characterized in that,
the rigid container has a first opening and a second opening; the flexible bladder is mounted within the rigid container and its inlet is mounted to the first opening, thereby forming a first space within the flexible bladder having a first opening and a second space within the rigid container having a second opening;
the first space is connected with the oxygen source and the mask assembly through a first opening, the valve set and the throttle valve; the second space is connected with the inflator pump through a second opening and the valve group.
Preferably, the valve set comprises a first valve, a second valve, a third valve and a fourth valve;
the first opening is connected with a first end of a three-way pipe; the second end of the three-way pipe is connected with the oxygen source through the first valve and the throttle valve; the second end of the three-way pipe is connected with the mask component through the second valve;
the second opening is connected with the first end of a four-way pipe; the second end of the four-way pipe is connected with the external environment through the third valve; the third end of the four-way pipe is connected with the inflator pump through the fourth valve; and the fourth end of the four-way pipe is connected with a first pressure gauge.
Preferably, the system controller is capable of controlling each valve of the valve group so that the valve group is in one of the following states
The first state: the first valve and the third valve are opened, and the second valve and the fourth valve are closed; at the moment, oxygen of the oxygen source is filled into the first space, and air in the second space is exhausted;
the second state: the first valve and the third valve are closed, the second valve is closed, and the fourth valve is opened; the inflator pump inflates the second space;
the third state: the first valve and the third valve are closed, the second valve is opened, and the fourth valve is closed; the first space outputs oxygen outwards.
Preferably, the automatic pressure gauge further comprises a self-calibrator comprising a rigid self-calibrating bottle and a second pressure gauge; the input port of the self-calibration bottle is connected with the second valve, and an opening is connected with the second pressure gauge.
Preferably, the mask assembly comprises a mask body and a mask synchronization switch;
the mask body has a contour adapted to form an airtight fit with a user's face, and a gas inlet;
the mask synchronous switch comprises a coaxial inner tube, a coaxial outer tube and a switch driver; the coaxial inner pipe and the coaxial outer pipe are respectively provided with corresponding large holes, and the coaxial outer pipe is also provided with a vent pipe and is connected with the second valve through the vent pipe.
Preferably, the outer diameter of the coaxial inner tube is substantially equal to the inner diameter of the coaxial outer tube, one end of each of the tubes is open and is communicated with the gas inlet of the mask body, and the other end of each of the tubes is provided with a switch driver and is sealed with the outside.
Preferably, the system controller is capable of controlling the switch driver to rotate the inner coaxial tube relative to the outer coaxial tube, so as to enable the mask assembly to be in one of the following states:
state 1: the large hole of the coaxial inner pipe is aligned with the large hole of the coaxial outer pipe; at this time, outside air can enter the mask body through the coaxial outer tube and the coaxial inner tube;
state 2: the large hole of the coaxial inner pipe is aligned with the small vent pipe of the coaxial outer pipe; oxygen output by the first space can enter the mask body through the second valve;
state 3: the perforation of the coaxial inner pipe is aligned with the pipe wall without the opening of the coaxial outer pipe; the mask body is now isolated from the environment.
Preferably, the first valve, the second valve, the third valve and the fourth valve are all normally closed solenoid valves.
A second aspect of the invention provides a method for calibrating an equivalent inspiratory apparatus according to the above technical solution, comprising the following steps:
step 101, controlling the valve set to be in the first state, slowly inflating the flexible air bag by the oxygen source through the throttle valve at a certain speed, and inflating a certain amount of oxygen into the flexible air bag by controlling the inflation time;
step 102, controlling the valve set to be in the second state, and inflating the second space by using the inflator pump to enable the pressure in the rigid container to be greater than one atmospheric pressure;
103, connecting the output end of the second valve to the input port of the self-calibration container;
step 104, controlling the valve group to be in the third state; and recording the reading of a second pressure gauge on the self-calibrator;
and 105, repeating the steps 101-104 for a plurality of times, and if the reading difference of the second pressure gauge is within 8% each time, proving that the same amount of inflation can be completed in the first space in the flexible air bag.
A third aspect of the invention provides a method for performing CT image acquisition with the aid of an equivalent amount of an inspiratory apparatus according to one of the above aspects, the method comprising the steps of:
step 201, installing a mask main body on the face of a patient, controlling the mask assembly to be in a state 1, a state 2 and a state 1 in sequence, and correspondingly enabling the patient to inhale, exhale and inhale again;
step 202, switching the mask assembly to a state 3, performing CT scanning, and switching the mask assembly to a state 2 after obtaining pictures to allow the patient to freely breathe;
step 203, determining interest points as required;
step 204, moving the CT bed to enable the fault of the point of interest to be positioned in a CT scanning plane;
step 205, controlling the mask assembly to be in a state 1, a state 2 and a state 1 in sequence, and correspondingly enabling the patient to inhale, exhale and inhale again;
in step 206, a CT single slice scan is performed.
Through the technical scheme, the invention can obtain the following technical effects.
(1) The volume of gas filled into the flexible air bag can be accurately controlled;
(2) the air in the lungs can be allowed to be exhausted as much as possible before the patient inhales;
(3) the oxygen filled in the flexible air bag can be fully sucked into the lungs of the patient during inspiration, and because the oxygen amount filled into the flexible air bag is equal every time, the oxygen amount sucked by the patient during CT scanning every time is also equal, thereby avoiding the error caused by breathing.
Drawings
FIG. 1 is a schematic structural diagram of a CT real-time positioning precision puncture system according to the present invention;
FIG. 2 is a schematic diagram of a robot structure of the CT real-time positioning precise puncture system in FIG. 1;
FIG. 3 is a schematic view of a robot hand configuration of the robot of FIG. 2;
FIG. 4 is a schematic structural view of a trocar holder of the robot of FIG. 2;
FIG. 5 is a schematic view of an equivalent suction gauge of the robot of FIG. 1;
figure 6 is a schematic view of a mask assembly of the isovolumetric aspirator of figure 5.
The meaning of the individual reference symbols in the figures is as follows:
10-CT scanning equipment, 20-a puncture robot, 30-a system control box, 40-an equivalent aspiration instrument and 50-a computer;
21-large-aperture bearing, 22-first connecting piece, 23-mechanical arm, 24-mechanical hand, 25-puncture angle controller, 26-box type sliding block, 27-inner sleeve driver, 28-second connecting piece, C1-upper case, C2-lower case, T1-outer case, T2-inner case, U-cantilever structural piece, M1-first motor, L1-first lead screw, B1-first nut, G1-outer gear and G2-inner rack;
241-puncture depth controller, 242-puncture driver, 243-depth control slider, 244-pressure plate, 245-trocar clamper, 246-first bearing, 247-first linear slide rail, 248-second bearing, 249-second linear slide rail, M2-second motor, L2-second lead screw, B2-second nut, M3-third motor, L3-third lead screw, B3-third nut;
401-flexible balloon, 402-rigid container, 403-throttle valve, 404-medical oxygen bottle, 405-inflator, 406-first pressure gauge, 407-second pressure gauge, 408-self-calibration bottle, 409-mask body, 410-coaxial outer tube, 411-coaxial inner tube, 412-switch driver, 413-small vent tube, 414-large hole, 415-system controller, K1-first valve, K2-second valve, K3-third valve, K4-fourth valve, K5-fifth valve, P1-three-way pipe, and P2-four-way pipe.
Detailed Description
The term "CT" used in the present invention means CT (computed tomography), which is an image inspection technique of performing cross-sectional scanning one by one around a certain portion of a human body together with a detector having a very high sensitivity by using a precisely collimated X-ray beam, gamma rays, ultrasonic waves, etc. The following can be classified according to the radiation used: x-ray CT (X-CT), and gamma-ray CT (gamma-CT).
The terms "proximal end" and "distal end" used herein refer to a positional relationship with respect to the CT machine, i.e., the end near the CT machine is the proximal end, and the end far away from the CT machine is the distal end.
As shown in fig. 1, a CT real-time positioning precise puncture system according to the present invention comprises: CT scanning equipment 10, puncture robot 20, control system 30, equivalent suction instrument 40, computer 50.
As shown in fig. 2, the puncture robot 20 of the CT real-time positioning precise puncture system in fig. 1 includes: a cabinet, a mechanical arm 23, a robot arm 24 and a puncture angle controller 25.
The piercing robot 20 is adapted to be positioned directly behind the CT scanning device 10. The chassis includes an upper chassis C1 and a lower chassis C2. The system control box is installed in the lower cabinet C2 of the piercing robot 20.
The upper cabinet C1 has a substantially cylindrical machine manhole in the middle, and a large bore bearing 21 is mounted at the proximal end of the machine manhole. When the piercing robot 20 is placed right behind the CT scanning device 10, the central axis of the machine manhole coincides with the central axis of the scanning hole of the CT scanning device 10. The large-aperture bearing 21 includes an outer sleeve T1 and an inner sleeve T2. The outer case T1 is mounted on the upper cabinet C1. The inner upper near end of the inner sleeve T2 is provided with a first connecting piece 22, and the lower end of the first connecting piece 22 is fixed with a box-type sliding block 26. The robot arm 23 is connected to the first link 22 via the box slide 26.
The far end of the mechanical arm 23 is arranged in the robot hole, is parallel to the central axis of the robot hole, and can move in a circular arc shape above the inner part of the hole of the CT scanning device 10 close to the outer circle of the robot hole along with the rotation of the inner sleeve T2 of the large-aperture bearing 21.
The robot arm 24 is disposed at a proximal end of the robot arm 23, and is configured to perform a puncturing operation.
The puncture angle controller 25 is disposed at a distal end of the robot arm 23, and is configured to control an angle of the puncture operation of the robot arm 24.
In a preferred embodiment, the distal end of the first connector 22 mounts a cantilevered structural member U parallel to the axis of the large bore bearing 22. The far end of the cantilever structure member U is provided with a first motor M1 and a first lead screw L1 parallel to the cantilever structure member. In a preferred embodiment, the cantilever structure U is a U-shaped channel. The shaft of the first motor M1 is connected with a first lead screw L1. A first nut B1 on the first threaded spindle L1 is fixed to the housing of the lancing drive 25. The first motor M1 can drive the first nut B1 to move on the first lead screw L1, so as to drive the puncture angle driver 25, the mechanical arm 23 and the robot arm 24 to move longitudinally in the bore of the CT scanning device, thereby positioning the trocar clamper 245 on the robot arm 24 in the X-ray scanning plane of the CT scanning device or moving the trocar clamper out of the CT scanning device.
In a preferred embodiment, a circular arc-shaped rack G2 is arranged below the inner part of the inner sleeve T2. The upper case C1 further includes an inner housing driver 27, and the inner housing driver 27 includes a gear G1 engaged with the circular arc rack G2, so as to drive the inner housing T2 to rotate. Those skilled in the art will appreciate that the arcuate rack G2 may be an internal or external rack, as desired.
In a preferred embodiment, an equivalent inspiratory meter 40 is also installed in the robot to eliminate breathing errors. The equivalent inspiratory apparatus 40 is capable of outputting an equivalent amount of oxygen each time the patient inhales. Before CT scanning, the patient inhales equal oxygen, so that the breathing error can be basically eliminated, and the patient can breathe freely.
The system control box 30 is connected to the computer 50 via an interface (e.g., RS 232). The puncture robot 20 can automatically and accurately aim the puncture trocar at the target point as long as it receives the puncture point and the target point determined by the doctor, and can automatically and accurately puncture the target point set in the patient body in real time. In a preferred embodiment, the computer 50 is disposed on a dedicated console, and is disposed adjacent to the control device of the CT scanning apparatus for cooperating therewith.
As shown in fig. 3, the robot hand 24 of the CT real-time positioning precise puncture robot according to the present invention includes: a penetration depth controller 241, a penetration driver 242, a trocar holder 245. The robot arm 24 is mounted at the proximal end of the robot arm 23 at substantially right angles to the robot arm 23.
In a preferred embodiment, the puncture depth controller 241 comprises a second motor M2, a second lead screw L2, a second nut B2, a first linear slide 247, and a depth control slider 243. The second motor M2 is fixed at the proximal end of the robot arm 23, the rotating shaft of the second motor M2 is connected with the second lead screw L2, the second nut B2 on the second lead screw L2 is connected with the depth control slider 243 of the first linear slide rail 247, the depth control slider 243 is connected with the puncture driver 242, and the second motor M2 can drive the puncture driver 25 to move up and down. In an alternative embodiment, the rotating shaft of the second motor M2 is arranged in a horizontal direction, the second lead screw L2 is arranged in a vertical direction, the rotating shaft of the second motor M2 is connected with a first bevel gear, the upper end of the second lead screw L2 is connected with a second bevel gear, the first bevel gear can be meshed with the second bevel gear, and the axes of the first bevel gear and the second bevel gear are perpendicular to each other.
In a preferred embodiment, the lancing drive 242 includes a third motor M3, a third lead screw L3, a third nut B3, and a pressure plate 244. The rotating shaft of the third motor M3 is connected to the third lead screw L3, and the third nut B3 on the third lead screw L3 is connected to the pressure plate 244. In a more preferred embodiment, the pressure plate 244 is "7" shaped, and the trocar disengages from the robot arm 24 whenever the pressure plate 244 is pressed to the lowermost end.
As shown in fig. 4, the trocar holder 245 of the CT real-time positioning precise puncture robot according to the present invention includes a connection plate a, a first strip-shaped plate b, and a second strip-shaped plate c. The first strip-shaped plate b and the second strip-shaped plate c are parallel to each other and perpendicular to the mechanical arm 6, and the upper ends of the first strip-shaped plate b and the second strip-shaped plate c are connected with the connecting plate a.
In addition, trocar holder 245 can also be used to hold a marking device prior to performing a puncturing action to mark the intended puncturing location to confirm that the set puncturing location actually coincides with the intended puncturing location. In a preferred embodiment, the marking device may be a marker pen adapted for use in a medical environment.
In a preferred embodiment, the surface of the second nut B2 facing the first linear slide 247 is provided with U-shaped wings, which are connected to the depth control slider 243 and the piercing driver 242.
As shown in fig. 5, the equivalent suction instrument 40 of the CT real-time positioning precise puncture robot according to the present invention includes: flexible bladder 401, rigid container 402, throttle 403, medical oxygen bottle 404, inflator 405, valve set, mask assembly, and system controller 415.
The rigid container 402 has a first opening and a second opening; the flexible bladder 401 is mounted in the rigid container 402 and its inlet is mounted to the first opening, thereby forming a first space having a first opening in the flexible bladder 401 and a second space having a second opening in the rigid container 402.
The first space is connected with the medical oxygen bottle and the mask assembly through a first opening, the valve set and the throttle valve 403. The second space is connected to the inflator 405 through a second opening and the valve assembly.
In a preferred embodiment, the valve set includes a first valve K1, a second valve K2, a third valve K3, and a fourth valve K4.
In a preferred embodiment, the first valve K1, the second valve K2, the third valve K3 and the fourth valve K4 are all normally closed solenoid valves.
Said first opening being connected to a first end of a tee pipe P1; the second end of the tee pipe P1 is connected with the medical oxygen bottle 404 through the first valve and the throttle valve 403. The second end of the tee P1 is connected to the mask assembly through the second valve K2.
In a preferred embodiment, a fifth valve K5 is also provided between the second valve K2 and the mask assembly to close the output of oxygen to the mask assembly, such as during a self-calibration procedure.
The second opening is connected with the first end of a four-way pipe P2; the second end of the four-way pipe P2 is connected with the external environment through the third valve; the third end of the four-way pipe P2 is connected with an inflator pump through the fourth valve; the fourth end of the four-way pipe P2 is connected with a first pressure gauge.
In a preferred embodiment, the system controller 415 is capable of controlling each valve of the valve set such that the valve set is in one of the following states.
The first state: the first valve K1 and the third valve K3 are opened, and the second valve K2 and the fourth valve K4 are closed. At this time, the oxygen in the medical oxygen bottle 404 fills the first space, the air in the second space is exhausted, and the first space and the second space are both kept at the external pressure.
The second state: the first valve K1 and the third valve K3 are closed, the second valve K2 is closed, and the fourth valve K4 is opened. At the moment, the inflator pumps inflate the second space, and the pressure in the second space is gradually increased.
The third state: the first valve K1 and the third valve K3 are closed, the second valve K2 is open, and the fourth valve K4 is closed. At the moment, the first space outputs oxygen outwards, and the pressure in the first space and the pressure in the second space are gradually reduced.
In a preferred embodiment, the isovolumetric aspirator 40 further comprises a self-calibrator comprising a rigid self-calibrating vial 406 and a second pressure gauge 407. The input port of the self-calibrating bottle 406 is connected to the second valve K2, and has an opening connected to the second pressure gauge.
As shown in fig. 6, the mask assembly includes a mask body 409 and a mask synchronization switch.
The mask body 409 has a contour adapted to form an airtight fit with the face of the user, and a gas inlet.
The mask synchronization switch includes an outer coaxial tube 410, an inner coaxial tube 411, and a switch driver 412. The coaxial inner tube 411 and the coaxial outer tube 410 are respectively provided with corresponding large holes 414. The coaxial outer tube 410 is further provided with a vent pipe 413, and is connected with the second valve K2 through the vent pipe 413.
The outer diameter of the coaxial inner tube 411 is substantially equal to the inner diameter of the coaxial outer tube 410, one end of each of the tubes is open and is communicated with the gas inlet of the mask body 409, and the other end of each of the tubes is provided with a switch driver 412 and is sealed from the outside.
The system controller 415 can control the switch driver 412 to rotate the inner coaxial tube 411 relative to the outer coaxial tube 410, thereby placing the mask assembly in one of the following states.
State 1: the large hole of the coaxial inner tube 411 is aligned with the small vent tube 413 of the coaxial outer tube 410; oxygen from the first volume can now enter the mask body 409 through the second valve K2.
State 2: the large aperture of the coaxial inner tube 411 is aligned with the large aperture of the coaxial outer tube 410; at this time, outside air can enter the mask body through the coaxial outer tube and the coaxial inner tube.
State 3: the large hole of the coaxial inner tube 411 is aligned with the unopened tube wall of the coaxial outer tube 410; the mask body 409 is now isolated from the environment.
The following describes a calibration method of the equivalent suction meter according to the above embodiment, and the procedure thereof is as follows.
Step 101, controlling the valve set to be in the first state, slowly inflating the flexible air bag 401 with the medical oxygen bottle through the throttle valve 403 at a certain speed, and controlling the amount of oxygen inflated into the flexible air bag by controlling the inflation time.
Step 102, controlling the valve set to be in the second state, and inflating the second space with the inflator 405 to make the pressure inside the rigid container 402 greater than one atmosphere.
And 103, connecting the output end of the second valve K2 to the input port of the self-calibration bottle 408.
Step 104, controlling the valve group to be in the third state; and records a reading from a second pressure gauge 407 on the self-calibrator.
Step 105, repeating steps 101-104 for a plurality of times, and if the reading of the second pressure gauge 407 is within 8% each time, it is proved that the same amount of inflation can be performed to the first space in the flexible bladder. In a more preferred embodiment, each reading of the second pressure gauge 407 is within 5%.
A method for performing CT image acquisition with the aid of an equivalent-quantity-of-inspiration instrument according to one of the above embodiments is described below, the steps of which are as follows:
step 201, installing the mask main body on the face of a patient, controlling the mask assembly to be in a state 1, a state 2 and a state 1 in sequence, and enabling the patient to inhale, exhale and inhale again correspondingly.
Step 202, switching the mask assembly to state 3, performing CT scan, and switching the mask assembly to state 2 after acquiring the picture to allow the patient to breathe freely.
In step 203, points of interest are determined as needed.
And step 204, moving the CT bed to enable the point of interest fault to be positioned in the CT scanning plane.
And step 205, controlling the mask assembly to be in a state 1, a state 2 and a state 1 in sequence, and enabling the patient to inhale, exhale and inhale again correspondingly.
In step 206, a CT single slice scan is performed.
Those skilled in the art will appreciate that when the mask assembly is in state 1, a certain amount of oxygen needs to be output to the mask assembly, and accordingly, a certain amount of oxygen needs to be inflated into flexible bladder 401 before switching to state 1. The control sequence of the valve set in the oxygen delivery process is the same as the calibration method of the equivalent inspiration meter, and is not repeated here.
A method for performing medical image acquisition and puncture by using the CT real-time positioning precise puncture robot according to the above embodiment is described as follows.
Step 301, installing the mask body on the face of a patient, controlling the mask assembly to be in a state 1, a state 2 and a state 1 in sequence, and enabling the patient to inhale, exhale and inhale again correspondingly.
Step 302, switching the mask assembly to state 3, performing CT scan, and switching the mask assembly to state 2 after acquiring the picture to allow the patient to breathe freely.
Step 303, determining a puncture point and a target point on the tomogram with the largest (or larger) tumor tomogram area.
And step 304, moving the CT bed to enable the puncture point fault of the patient to be positioned in the CT scanning plane.
And 305, controlling the mask assembly to be in a state 1, a state 2 and a state 1 in sequence, and enabling the patient to inhale, exhale and inhale again correspondingly.
Step 306, the mask assembly is switched to the state 3, CT single-layer scanning is carried out, at the moment, a doctor can see that the trocar aims at the puncture point and the target point on a CT computer screen, and accurate puncture can be completed by sending a puncture instruction.
Although particular embodiments of the invention have been described and illustrated in detail, it should be understood that various equivalent changes and modifications could be made to the above-described embodiments according to the inventive concept, and that the resulting functional effects would still fall within the scope of the invention, without departing from the spirit of the description and drawings.