CN112336971A - Rectum slow-release treatment and nursing device - Google Patents

Rectum slow-release treatment and nursing device Download PDF

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Publication number
CN112336971A
CN112336971A CN202011244285.5A CN202011244285A CN112336971A CN 112336971 A CN112336971 A CN 112336971A CN 202011244285 A CN202011244285 A CN 202011244285A CN 112336971 A CN112336971 A CN 112336971A
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CN
China
Prior art keywords
air bag
wall
release treatment
slow
rectal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN202011244285.5A
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Chinese (zh)
Inventor
纪丽
杨娅娟
赵培娜
高宗跃
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henan University of Traditional Chinese Medicine HUTCM
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Henan University of Traditional Chinese Medicine HUTCM
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Publication date
Application filed by Henan University of Traditional Chinese Medicine HUTCM filed Critical Henan University of Traditional Chinese Medicine HUTCM
Priority to CN202011244285.5A priority Critical patent/CN112336971A/en
Publication of CN112336971A publication Critical patent/CN112336971A/en
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/88Draining devices having means for processing the drained fluid, e.g. an absorber
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/105Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1075Balloon catheters with special features or adapted for special applications having a balloon composed of several layers, e.g. by coating or embedding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1042Alimentary tract
    • A61M2210/1064Large intestine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1042Alimentary tract
    • A61M2210/1067Anus

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)

Abstract

The invention relates to a rectum slow-release treatment and nursing device, which comprises an elastic air bag with a smooth curved surface, wherein water-absorbing particles are filled in the air bag, and a plurality of vent holes smaller than the water-absorbing particles are arranged on the wall of the air bag; the invention can solve the problems of inconvenient administration, high frequency and accidental overflow of tissue fluid in intestinal tracts of the existing anorectal medicaments, reduces the exposure of private parts of patients, eliminates the worry and worry of the patients and enables the patients to be easily put into normal production and life.

Description

Rectum slow-release treatment and nursing device
Technical Field
The invention relates to an anorectal auxiliary treatment and nursing device, in particular to a rectal slow-release treatment and nursing device.
Background
The anorectal diseases comprise common diseases such as proctitis and hemorrhoids, the intestinal tract is positioned at the final stage of the circulatory system of a human body, so the drug effect of oral drugs is difficult to reach effectively, auxiliary treatment is often needed by means of external drugs such as ointment, suppository and the like, but the patients are difficult to touch the application part of the external drugs, so the assistance of medical care personnel or accompanying personnel is needed, however, due to the privacy of the part, the exposure of the privacy part of the patients is inevitably caused in the application process of the external drugs, certain physiological and psychological troubles are brought to the patients and the medical care personnel, therefore, the drugs can be easily and independently applied by the patients as much as possible, and the drug application frequency is reduced, so that the pain and the embarrassment of the patients during application are reduced.
In addition, for anorectal diseases such as proctitis and hemorrhoids, purulent secretion generated in intestinal tracts is mixed in intestinal tissue fluid and often overflows through anus uncontrollably, so that clothes, bed sheets and other articles of a patient are stained, normal work and life of the patient are affected, a great psychological burden is brought to the patient, the secretion erodes the perianal skin for a long time, and eczema and perianal infection are caused.
Disclosure of Invention
In order to overcome the technical defects in the prior art, the invention provides a rectal sustained-release treatment and nursing device, which aims to solve the problems of inconvenience and high frequency of administration of the existing anorectal drugs and accidental overflow of tissue fluid in intestinal tracts, reduce the exposure of private parts of patients, eliminate worry and worry of the patients and enable the patients to be easily put into normal production and life.
The technical scheme for solving the problem is as follows: the air bag comprises an elastic air bag with a smooth curved surface, water-absorbing particles are filled in the air bag, and a plurality of vent holes with the diameter smaller than that of the water-absorbing particles are arranged on the bag wall of the air bag; the air bag is internally provided with a pull rope, one end of the pull rope is connected with the inner wall of one end of the air bag, and the other end of the pull rope penetrates through the other end of the air bag in a sealing and sliding manner and is arranged outside the air bag.
Preferably, the wall of the balloon is a double-wall structure, the double-wall walls of the balloon are connected through a plurality of micro-tubes, and fluid is filled between the double-wall walls of the balloon.
Preferably, the air bag has a plurality of storage bags on the bag wall, the storage bags are provided with outward openings, and the storage bags are filled with sustained-release preparations.
Drawings
Fig. 1 is a front view of the present invention.
3 fig. 3 2 3 is 3 a 3 cross 3- 3 sectional 3 view 3 a 3- 3 a 3 of 3 the 3 present 3 invention 3. 3
Fig. 3 is an isometric view of the present invention.
Fig. 4 is an elevation sectional view of the balloon of the present invention in a double-walled structure.
Fig. 5 is a sectional view taken along line B-B of fig. 4 according to the present invention.
Fig. 6 is a cross-sectional view taken along line C-C of fig. 4 in accordance with the present invention.
FIG. 7 is an axial sectional view of the balloon of the present invention in a double-walled structure.
Detailed Description
The following describes embodiments of the present invention in further detail with reference to the accompanying drawings.
As shown in fig. 1 to 7, the present invention comprises a horizontally arranged smooth curved elastic air bag 1, the interior of the air bag 1 is filled with water-absorbing particles 2, and the wall of the air bag 1 is provided with a plurality of vent holes 3 with diameters far smaller than the diameters of the water-absorbing particles 2, so that external water can enter the interior of the air bag 1 through the vent holes 3 and then be absorbed by the water-absorbing particles 2; the air bag 1 is internally provided with a pulling rope 4 which is horizontally arranged, the left end of the pulling rope 4 is connected with the inner wall of the left end of the air bag 1, and the right end of the pulling rope 4 penetrates through the right end of the air bag 1 in a sealing and sliding manner and is arranged outside the air bag 1.
When the anal sphincter muscle-controlled air bag is used, the air bag 1 is inserted into the anus of a patient through the left end of the air bag, after the air bag 1 completely enters the anus, the air bag 1 is pushed into the anal tube and is attached to the inner wall of the anal tube or the intestinal tract under the contraction action of the anal sphincter muscle, and the air bag is blocked by the anus so that the air bag cannot fall off; due to the obstruction of the air bag 1, the water absorbing particles 2 are not in direct contact with the inside of the intestinal tract, so that interstitial fluid (such as pancreatic juice, bile, secretion of the intestine and the like) adsorbed on the inner surface of the intestinal tract can not be washed by hands, dehydration and dryness of the inner surface of the intestinal tract can not be caused, and the intestinal environment can not be damaged; when the tissue fluid in the intestinal tract is excessive and flows towards the anus, the flowing tissue fluid flows through the air bag 1 and enters the air bag 1 through the air holes 3, and then is absorbed by the water absorption particles 2, so that the tissue fluid is effectively prevented from overflowing, and the drying and sanitation of the perianal environment of a patient are kept; meanwhile, the water-absorbing particles 2 expand after hand washing moisture, so that the air bag 1 expands and extends along the direction of the anal canal or the intestinal tract to be further tightly attached to the anal canal or the intestinal tract and prevent the tissue fluid from overflowing.
According to the difference of different patient's anal canal and intestinal internal diameter, after gasbag 1 was put into completely, appropriate pulling stay cord 4 made gasbag 1 produce horizontal compression to guarantee 1 outer wall of gasbag and anal canal or intestinal inner wall's inseparable laminating.
After use, the pull rope 4 is pulled to pull the air bag 1 out of the body, or the air bag 1 is discharged along with defecation.
Further, gasbag 1 in have retaining ring 5 of arranging on stay cord 4, when pulling stay cord 4 makes gasbag 1 transversely shrink, the right-hand member of gasbag 1 forms to retaining ring 5 and blocks to make stay cord 4 stimulate reliably to stop after the predetermined position, a pulling distance for limiting stay cord 4, prevent that the excessive compression to gasbag 1 leads to gasbag 1 to break, avoid causing excessive extrusion to anal canal or intestinal inner wall, and prevent to use after the pulling stay cord 4 pulls out the in-process with gasbag 1, gasbag 1's excessive transverse contraction leads to it can't be pulled out by anus department is external.
Furthermore, the air bag 1 is provided with a double-layer bag wall, two ends of the double-layer bag wall are correspondingly connected, the double-layer bag wall of the air bag 1 is connected through a plurality of micro tubes 6 uniformly distributed along the outline shape of the air bag 1, the inner holes of the micro tubes 6 are used as vent holes 3 to realize the communication between the interior of the air bag 1 and the external environment, and fluid such as clean air, inert gas or pure water is filled between the double-layer bag walls of the air bag 1 to reinforce the overall strength of the air bag 1, so that the air bag 1 can bear certain transverse pressure without generating large deformation, and the air bag 1 is prevented from entering the anus due to over-softness; simultaneously, double-deck bag wall can increase the interval between 1 inside and anal canal or the intestinal of gasbag, guarantees that granule 2 that absorbs water can't directly touch anal canal or intestinal inner wall, prevents that granule 2 that absorbs water from leading to the inner wall dehydration of anal canal or intestinal to be dry and astringent with the moisture absorption of anal canal or intestinal inner wall, avoids the patient that leads to from this to remove the in-process because of the misery that produces of the friction between gasbag 1 and anal canal or the intestinal inner wall.
Furthermore, a plurality of outward-protruding object placing bags 7 are uniformly distributed on the bag wall of the air bag 1 along the contour shape of the air bag 1, the plurality of object placing bags 7 and the plurality of vent holes 3 are distributed in a staggered manner and do not overlap, an opening 8 facing the outer side of the air bag 1 is formed in each object placing bag 7, and a sustained-release preparation 9 such as a sustained-release tablet or a sustained-release soft capsule is arranged in each object placing bag 7; the outward bulge of the storage bag 7 can increase the distance between the air bag 1 and the inner wall of the anal canal or the intestinal canal, so that the water-absorbing particles 2 can not directly contact the inner wall of the anal canal or the intestinal canal; the sustained release preparation 9 is exposed in the intestinal environment through the opening 8 and contacts with the anal canal or the inner wall of the intestinal tract, and is used for slowly releasing the medicinal components to realize bacteriostasis, repair and treatment of the intestinal tract; meanwhile, the water swelling of the water-absorbing granules 2 can promote the drug release of the sustained-release preparation 9, so that when the sustained-release preparation 9 in the form of soft capsules is selected, the addition of a pushing agent (such as high molecular weight polyethylene glycol) can be saved, and the release of the liquid medicine in the soft capsules can be directly driven by the water-absorbing granules 2.
Further, the double-layer bag wall of the airbag 1 is connected by a plurality of annular walls 10 which are uniformly distributed along the contour shape of the airbag 1 and radially arranged along the horizontal axis of the airbag 1, so that an article placing bag 7 is formed between the double-layer bag wall of the airbag 1 and the annular walls 10, the article placing bags 7 and the vent holes 3 are distributed in a staggered manner and do not overlap, a plurality of openings 8 which correspond to the annular walls 10, namely the article placing bags 7, are formed in the outer-layer bag wall of the airbag 1, and sustained-release preparations 9 such as sustained-release tablets or sustained-release capsules are arranged in the article placing bags 7.
Furthermore, the two ends of the air bag 1 are respectively thickened to ensure that the air bag 1 has better profile shape supporting force, and the influence on the using effect caused by the inward sinking of the left end of the air bag 1 when the pull rope 4 is pulled is avoided.
Further, the inner wall of the air bag 1 is evenly distributed with a plurality of reinforcing ribs 11 arranged along the length direction of the air bag 1 along the circumference of the horizontal axis of the air bag 1, so that the supporting strength of the air bag 1 is improved, and the situation that the air bag 1 is too soft and cannot smoothly enter and exit the anus is avoided.
Furthermore, the right end of the airbag 1 is provided with a slender tail tube 12 extending rightwards along the length direction of the airbag 1, and the right end of the pull rope 4 penetrates the tail tube 12 in a sealing sliding way along the length direction of the tail tube 12 and is arranged outside the airbag 1; tail pipe 12 is used for guaranteeing that 1 entering anal canal of gasbag or intestinal back can carry out effective control to gasbag 1 through tail pipe 12 all the time to in the entering degree of depth, the rotation angle etc. of adjusting gasbag 1, experience with guaranteeing safer, convenient use, prevent that gasbag 1 from getting into the intestinal depths, eliminate anxiety and uneasy that bring for the patient from this.
Furthermore, the left end of the tail pipe 12 is connected with the air bag 1, the right end of the tail pipe 12 is provided with an umbrella-shaped plug 13 with the radius gradually increasing from left to right, the end face of the plug 13 connected with the tail pipe 12 is provided with a plurality of micropores 14 uniformly distributed along the circumference of the axis of the tail pipe 12, and the micropores 14 extend leftwards along the length direction of the tail pipe 12 to be communicated with the inside of the air bag 1; when the air bag 1 enters the anal canal or the intestinal tract, the plug 13 is tightly attached to the anus of a patient, on one hand, the air bag 1 is prevented from being excessively deep, on the other hand, the overflowing intestinal tissue fluid can be blocked, and articles such as clothes or bed sheets are prevented from being stained, and meanwhile, when the overflowing tissue fluid is more, the capillary suction force generated by the micropores 14 absorbs the tissue fluid into the air bag 1, and further the absorption is completed by the water absorption particles 2; during the period that the air sac 1 is arranged in the intestinal tract, the tail tube 12 is in a slender tubular shape, so that no obvious expansion stimulation is generated on the anal sphincter, the discomfort of a patient is not caused, and the patient can adapt quickly.
Furthermore, a plurality of stripes 15 are uniformly distributed along the circumference of the axis of the tail tube 12 on the end surface of the plug 13 connected with the tail tube 12, and the plurality of stripes 15 enable the plug 13 to be tightly matched with the folds at the anus of the patient, so that a better overflow blocking effect is achieved.
Further, the balloon 1 is, for example, an ellipsoid, a fusiform or a capsule to reduce the resistance when entering the anus.
Furthermore, the water-absorbing particles 2 are spherical particles made of water-absorbing materials such as water-absorbing resin, medical grade polyvinyl alcohol, high molecular weight polyethylene glycol and the like.
The invention can be used for external drug treatment of anorectal patients, and can also effectively prevent accidental leakage of intestinal tissue fluid, so that the patients can eliminate worry, work and life.
The air bag adopted by the invention is used as a carrier of the medicine, so that the medicine can be tightly attached to the inner wall of the intestinal tract, the absorption of the medicine is promoted, the sustained-release preparation can greatly prolong the efficacy time of the medicine, a patient does not need to frequently replace the medicine, and the exposure of private parts is reduced; the water absorption particles are arranged in the air bag, so that redundant intestinal tissue fluid can be absorbed, and the intestinal tissue fluid is prevented from overflowing through the anus; in addition, the water absorption swelling effect of the water absorption particles can also be used as a pushing agent of the sustained-release preparation, so that the cost and the manufacturing difficulty of the sustained-release preparation are reduced.
The invention adopts the pull rope to control the deformation of the air bag, so that the air bag can adapt to and be tightly attached to the inner diameters of intestinal tracts of different patients, and can be used for conveniently taking out the air bag, thereby improving the sanitation and convenience of the nursing process.
The capillary suction force generated by the micropores can suck the tissue fluid leaked from the anus back into the air bag again and be completely absorbed by the water absorption particles, and the water absorption particles in the air bag are not in direct contact with the intestinal tract, so that the part of sucked tissue fluid cannot cause backflow pollution to the intestinal tract, and the secondary infection of the intestinal tract is effectively avoided.

Claims (10)

1. A rectum slow-release treatment and nursing device comprises an air bag (1), and is characterized in that the air bag (1) is filled with water-absorbing particles (2), and a plurality of vent holes (3) are formed in the air bag (1); a pull rope (4) is arranged in the air bag (1), one end of the pull rope (4) is connected with one end of the air bag (1), and the other end of the pull rope (4) penetrates through the other end of the air bag (1) in a sliding mode and is arranged outside the air bag (1).
2. A rectal slow release treatment and care device according to claim 1, characterised in that the balloon (1) has a collar (5) disposed on the pull cord (4).
3. The rectal slow-release treatment and nursing device according to claim 1, characterized in that the wall of the air bag (1) is a double-wall structure, the double-wall of the air bag (1) is connected through a plurality of micro-tubes (6) to realize the communication between the inside and the outside of the air bag, and the double-wall of the air bag (1) is filled with fluid.
4. The rectal sustained-release treatment and care device according to claim 1, characterized in that the wall of the air bag (1) is provided with a plurality of outward-protruding storage pockets (7), the storage pockets (7) are provided with outward-facing openings (8), and the storage pockets (7) are filled with sustained-release preparations (9).
5. The rectal sustained-release treatment and care device according to claim 3, characterized in that the double-layer wall of the air bag (1) is connected by a plurality of annular walls (10), so that a storage bag (7) is formed between the double-layer wall of the air bag (1) and the annular walls (10), a plurality of openings (8) corresponding to the annular walls (10) one by one are formed on the outer-layer wall of the air bag (1), and a sustained-release preparation (9) is filled in the storage bag (7).
6. A rectal slow release treatment and care device according to claim 1, characterised in that the two ends of the balloon (1) are respectively thickened.
7. The rectal slow-release treatment and care device according to claim 1, characterized in that a plurality of reinforcing ribs (11) arranged along the length direction of the air bag (1) are uniformly distributed on the inner wall of the air bag (1) in the circumference.
8. A rectal slow release treatment and care device according to any one of claims 1 to 7, characterised in that the other end of the balloon (1) has a tail tube (12) extending outwards, and the other end of the pull string (4) is slidably arranged outside the balloon (1) through the tail tube (12).
9. The rectum slow-release treatment and nursing device according to claim 8, wherein one end of the tail tube (12) is connected with the air bag (1), the other end of the tail tube (12) is provided with a plug (13), the end surface of the plug (13) connected with the tail tube (12) is provided with a plurality of micropores (14) distributed circumferentially, and the micropores (14) extend along the length direction of the tail tube (12) to be communicated with the inside of the air bag (1).
10. A rectal slow release treatment and care device according to claim 9, characterised in that the end face of the plug (13) connected to the tailpipe (12) is provided with a plurality of circumferential stripes (15).
CN202011244285.5A 2020-11-10 2020-11-10 Rectum slow-release treatment and nursing device Withdrawn CN112336971A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011244285.5A CN112336971A (en) 2020-11-10 2020-11-10 Rectum slow-release treatment and nursing device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011244285.5A CN112336971A (en) 2020-11-10 2020-11-10 Rectum slow-release treatment and nursing device

Publications (1)

Publication Number Publication Date
CN112336971A true CN112336971A (en) 2021-02-09

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CN202011244285.5A Withdrawn CN112336971A (en) 2020-11-10 2020-11-10 Rectum slow-release treatment and nursing device

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113368378A (en) * 2021-08-04 2021-09-10 河南省中医院(河南中医药大学第二附属医院) Rectum slow-release treatment and nursing device
CN119770831A (en) * 2024-12-30 2025-04-08 杭州糖吉医疗科技有限公司 Air bag with directional adjusting function and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113368378A (en) * 2021-08-04 2021-09-10 河南省中医院(河南中医药大学第二附属医院) Rectum slow-release treatment and nursing device
CN119770831A (en) * 2024-12-30 2025-04-08 杭州糖吉医疗科技有限公司 Air bag with directional adjusting function and application thereof

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Application publication date: 20210209