CN112185543A - Construction method of medical induction data flow classification model - Google Patents

Construction method of medical induction data flow classification model Download PDF

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CN112185543A
CN112185543A CN202010925639.6A CN202010925639A CN112185543A CN 112185543 A CN112185543 A CN 112185543A CN 202010925639 A CN202010925639 A CN 202010925639A CN 112185543 A CN112185543 A CN 112185543A
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孙乐
虞千迪
郭宇焱
瞿治国
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Abstract

The invention discloses a construction method of a medical induction data flow classification model, which comprises the following steps: the method for training and obtaining the medical induction data flow classification model based on the combination of CNN and LSTM by adopting an automatic supervision learning method comprises the following steps: inputting unmarked data into a sparse self-encoder of a medical induction data stream classification model for training so as to enable the input and the output of the model to be consistent; inputting the data with the labels into a trained sparse self-encoder, and outputting to obtain a corresponding classification result; training a medical induction data flow classification model based on a deep separable convolution method, obtaining a lightweight medical induction data flow classification model, and storing the obtained lightweight medical induction data flow classification model in a cloud service library or deploying the lightweight medical induction data flow classification model on edge equipment. According to the invention, by constructing an efficient and accurate lightweight model, higher abnormality diagnosis accuracy can be ensured, and high-precision disease classification can be realized. The method meets the requirement of light weight while meeting high reasoning accuracy, and is effectively deployed.

Description

Construction method of medical induction data flow classification model
Technical Field
The invention relates to a construction method of a medical induction data flow classification model, and belongs to the technical field of medical induction data processing.
Background
One major problem faced with anomaly detection based on medical sensing data is the lack of tagged data. The marking of data requires professional medical knowledge and the marking process is complex and time consuming. The large-scale high-precision deep learning model can ensure higher abnormality diagnosis accuracy, and occupies a large amount of memory and computing resources when actually deployed and used. For different application scenarios, medical sensing data flow classification models with different inference accuracy and different scales (i.e. different spatial and temporal complexities) need to be proposed.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a construction method of a medical induction data flow classification model, which is based on an automatic supervision learning theory and designs an efficient and accurate medical induction data flow classification model; based on a deep separable convolution method, a lightweight class model of the medical induction data stream is designed, and the model can be effectively and quickly deployed on a cloud service library or various resource-limited devices.
The invention specifically adopts the following technical scheme to solve the technical problems:
a construction method of a medical induction data flow classification model comprises the following steps:
the method for training and obtaining the medical induction data flow classification model based on the combination of CNN and LSTM by adopting an automatic supervision learning method comprises the following steps: inputting unmarked data into a sparse self-encoder of a medical induction data stream classification model for training so as to enable the input and the output of the model to be consistent; inputting the data with the labels into a trained sparse self-encoder, and outputting to obtain a corresponding classification result;
training a medical induction data flow classification model based on a deep separable convolution method to obtain a lightweight medical induction data flow classification model, which specifically comprises the following steps:
segmenting a time collected by a sensor using a sliding window techniqueHuman body induction data flow in the time interval is divided into n sections of multidimensional time sequence data: x is the number of1,...,xnWherein n belongs to Z, and n is more than or equal to 0; z is an integer set;
inputting the segmented n segments of multi-dimensional time sequence data into a medical induction data stream classification model for classification: extracting features of the multi-dimensional time series data within each sliding window, and predicting time series data within a variable time length from the output of the unit time and the time series data of the next unit time; classifying whether the predicted time sequence data is abnormal or not, obtaining and outputting a classification result, and obtaining a lightweight medical induction data stream classification model;
and storing the obtained lightweight medical induction data flow classification model in a cloud service library or deploying the lightweight medical induction data flow classification model on edge equipment.
Further, as a preferred technical solution of the present invention, in the method, the medical sensing data flow classification model is composed of two LSTM layers, a full connection layer and a softmax output layer, and edges between the two connection layers have weights.
Further, as a preferred technical solution of the present invention, the data conversion between two cells in the LSTM layer is input to the bottom hidden layer
Figure BDA0002666227490000021
Wherein ilowerIs an input to the bottom hidden layer; f () is an activation function;
Figure BDA0002666227490000022
is the weight connecting the edges of the upper unit and the lower unit; n is the output number of the upper layer; onIs the output of a cell; blowerIs an offset value.
Further, as a preferred technical solution of the present invention, a depth separable convolutional network including a plurality of convolutional layers is disposed inside each cell of the LSTM layer; the convolutional layers include two types: 3 x 3Depth-wise convolutional layers and 1 x 1 convolutional layers, and the two types of convolutional layers are arranged at intervals, and each convolutional layer is followed by a batch standardized BN layer and a ReLU activation layer.
Further, as a preferred embodiment of the present invention, the method classifies whether the predicted time-series data is abnormal or not, specifically:
due to n predicted time series data { x1,...,xnThere are m digital signals for each data sample
Figure BDA0002666227490000023
And, the ith predicted time-series data xi∈xn
Let the true value of the n time-series data be
Figure BDA0002666227490000024
The error of the jth element in the ith time-series data is
Figure BDA0002666227490000025
Defining time series data x for multivariate Gaussian ith predictioniError vector e ofiThe distribution p of (A) is:
Figure BDA0002666227490000026
wherein
Figure BDA0002666227490000027
Is an n x 1 vector and is,
Figure BDA0002666227490000028
is an n × n matrix;
if p (e)i(ii) a Mu; xi is less, then called xiIs a normal time series data, otherwise, xiIs anomalous time series data, in which is an error threshold.
Further, as a preferred technical solution of the present invention, the method further includes performing a segmentation removal on the collected human body sensing data stream by using a conventional segmentation removal method.
By adopting the technical scheme, the invention can produce the following technical effects:
the method of the invention obtains a high-precision medical induction data flow classification model based on CNN and LSTM based on self-supervision learning method training, and uses unlabelled and labeled data to train the medical induction data flow classification model, wherein the integrated model is the combination of CNN and LSTM, CNN can learn local characteristics and can share weight, LSTM can learn the front and back dependency relationship of data, and the two complement each other, thereby improving the accuracy of prediction. And moreover, a lightweight medical induction data stream classification model is obtained by training based on a depth separable convolution technology, and a lightweight full-precision model idea is adopted, so that a system deployed at the edge has two characteristics: light weight and high inference accuracy. The large-scale high-precision medical induction data flow classification model can ensure higher abnormal diagnosis accuracy and realize high-precision disease classification. The lightweight medical induction data flow classification model meets the requirement of lightweight while meeting high reasoning accuracy, and can be deployed on resource-limited equipment such as a cloud service library or edge mobile equipment.
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FIG. 1 is a schematic flow chart of a model training method for the self-supervised learning method adopted in the present invention.
FIG. 2 is a schematic diagram of a model trained based on the deep separable convolution method employed in the present invention.
Detailed Description
The following describes embodiments of the present invention with reference to the drawings.
The invention provides a construction method of a medical induction data flow classification model, which specifically comprises the following steps:
step one, training and obtaining a medical induction data flow classification model based on combination of CNN and LSTM by adopting a self-supervision learning method, which comprises the following steps:
for a disease domain, such as cardiovascular disease, a large-scale, full-precision depth model can be trained, deployed in the cloud. Considering that the initial period of practical collection of labeled medical data is very limited, the invention adopts a self-supervision learning method to train a medical induction data flow classification model based on combination of CNN and LSTM, as shown in FIG. 1, including:
firstly, inputting unlabelled data into a sparse self-encoder of a medical induction data stream classification model for training, so that the input and the output of the model are consistent. This allows learning of important features in the sample and obtaining a better characterization than the original input data. The output of the hidden layer obtained after the sparse self-encoder is trained is a better representation of the original input data.
The tagged data is then input into a trained sparse autoencoder to obtain a better representation of the features. The processed labeled data is used for training a medical induction data flow classification model, wherein the integrated model is the combination of CNN and LSTM. CNN can learn local characteristics and weight sharing, and LSTM can learn the front-back dependency relationship of data, and the front-back dependency relationship complement each other, so that the accuracy of prediction is improved. Thus, a prediction result output, i.e., a classification result of the corresponding sample, can be obtained.
And secondly, training a medical induction data flow classification model based on a deep separable convolution method to obtain a lightweight medical induction data flow classification model. On the basis of early work, a lightweight accurate convolution algorithm based on deep learning is developed and is released in a cloud service library in a micro-service mode or is deployed on edge equipment. The invention adopts the thought of a light-weight full-precision model, and ensures that a system deployed at the edge has two characteristics: light weight and high inference accuracy.
Training a medical induction data flow classification model based on a depth separable convolution method, extracting the characteristics of multi-dimensional time sequence data in each sliding window, and predicting the time sequence data in variable time length according to the output of unit time and the time sequence data of the next unit time; classifying whether the predicted time sequence data is abnormal or not, obtaining and outputting a classification result, and obtaining a lightweight medical induction data stream classification model; the specific process is as follows:
firstly, a sliding window technology is adopted to segment a human body induction data stream collected by a sensor in a time period, and the human body induction data stream is segmented into n segments of multidimensional time sequence data: x is the number of1,...,xnWherein n belongs to Z, and n is more than or equal to 0; z is an integer set; and inputting the segmented n segments of multi-dimensional time sequence data into a medical induction data flow classification model for classification.
The medical induction data flow classification model is an integrated model of CNN and LSTM for time series, the architecture of the model is shown in FIG. 2, and the model consists of four functional layers: two LSTM layers, one full link layer and one softmax output layer, where the edges between the two links have weights. One cell within the LSTM layer represents one time unit. Data conversion between two cells, i.e. input to the bottom hidden layer
Figure BDA0002666227490000041
Wherein ilowerIs an input to the bottom hidden layer; f is an activation function;
Figure BDA0002666227490000042
is the weight connecting the edges of the upper unit and the lower unit; n is the output number of the upper layer; onIs the output of a cell; blowerIs an offset value. Since each cell of the LSTM layer has a function of controlling the flow of sensing information and a unique multiplication structure of the model, the model can predict time series data in a variable time length according to the output of a unit time and time series data of the next unit time.
Deep separable convolutional networks are designed inside each LSTM cell, and the characteristics of the multi-dimensional time sequence data in each sliding window are extracted. The depth-in-cell separable convolutional network architecture comprises a plurality of convolutional layers, such as 25 layers. There are two types of convolutional layers: 3X 3Depth-wise convolutional layers and 1X 1 convolutional layers. The two types of convolution layers are arranged at intervals. Each convolutional layer is followed by a bulk standardized BN layer and a ReLU activation layer.
After the training of the model is completed, the method is usedIt is possible to classify whether the predicted time-series data is abnormal or not. For this reason, the present invention assumes that the error in predicting time series data is derived from the fact that the true time series fits a multivariate Gaussian distribution. Due to n predicted time series data { x1,...,xnThere are m digital signals for each sample
Figure BDA0002666227490000043
Figure BDA0002666227490000051
And ith predicted time-series data xi∈xn(ii) a . Let the true value of the n time-series data be
Figure BDA0002666227490000052
The error of the jth element in the ith time-series data is
Figure BDA0002666227490000053
By using
Figure BDA0002666227490000054
Figure BDA0002666227490000055
Time series data x defining multivariate Gaussian ith predictioniError vector e ofiDistribution p of (a). Wherein
Figure BDA0002666227490000056
Is an n x 1 vector and is,
Figure BDA0002666227490000057
is an n × n matrix. If p (e)i(ii) a Mu; xi is less, then called xiIs a normal time series data, otherwise, xiIs anomalous time series data, in which is an error threshold.
And step three, finally, storing the obtained lightweight medical induction data flow classification model in a cloud service library, and publishing the model in the cloud service library in a micro-service mode, or deploying the model on edge equipment, and deploying and storing the model on a cloud server or edge mobile equipment and other equipment with limited resources.
In addition, the method can also adopt a conventional segmentation removing method, and the conventional segmentation removing method is adopted to carry out segmentation removal on the acquired human body induction data stream, namely, before data is input into the model, useless segments are removed, and only segments with possible exceptions or exception prefixes are reserved. Here, the regular segment refers to a segment that maintains a daily state. For example, an abnormality of a patient with long-term atrial fibrillation refers to an abnormal ECG signal caused by other diseases, which are developed on the basis of atrial fibrillation in a conventional segment.
In conclusion, the method can ensure higher accuracy of abnormal diagnosis and realize high-precision disease classification by constructing an efficient and accurate lightweight medical induction data stream classification model. The lightweight medical induction data flow classification model meets the requirement of lightweight while meeting high reasoning accuracy, and can be deployed on a cloud service library or edge equipment.
The embodiments of the present invention have been described in detail with reference to the drawings, but the present invention is not limited to the above embodiments, and various changes can be made within the knowledge of those skilled in the art without departing from the gist of the present invention.

Claims (6)

1. A construction method of a medical induction data flow classification model is characterized by comprising the following steps:
the method for training and obtaining the medical induction data flow classification model based on the combination of CNN and LSTM by adopting an automatic supervision learning method comprises the following steps: inputting unmarked data into a sparse self-encoder of a medical induction data stream classification model for training so as to enable the input and the output of the model to be consistent; inputting the data with the labels into a trained sparse self-encoder, and outputting to obtain a corresponding classification result;
training a medical induction data flow classification model based on a deep separable convolution method to obtain a lightweight medical induction data flow classification model, which specifically comprises the following steps:
the method comprises the following steps of adopting a sliding window technology to segment a human body induction data stream in a time period collected by a sensor, wherein the human body induction data stream is segmented into n segments of multi-dimensional time sequence data: x is the number of1,...,xnWherein n belongs to Z, and n is more than or equal to 0; z is an integer set;
inputting the segmented n segments of multi-dimensional time sequence data into a medical induction data stream classification model for classification: extracting features of the multi-dimensional time series data within each sliding window, and predicting time series data within a variable time length from the output of the unit time and the time series data of the next unit time; classifying whether the predicted time sequence data is abnormal or not, obtaining and outputting a classification result, and obtaining a lightweight medical induction data stream classification model;
and storing the obtained lightweight medical induction data flow classification model in a cloud service library or deploying the lightweight medical induction data flow classification model on edge equipment.
2. The method for constructing the medical sensing data flow classification model according to claim 1, wherein the medical sensing data flow classification model in the method is composed of two LSTM layers, a full connection layer and a softmax output layer, and edges between the two connection layers have weights.
3. The method of claim 2, wherein the data transformation between two cells in the LSTM layer is input to the bottom hidden layer
Figure FDA0002666227480000011
Wherein ilowerIs an input to the bottom hidden layer; f () is an activation function;
Figure FDA0002666227480000012
is the weight connecting the edges of the upper unit and the lower unit; n is the output number of the upper layer; onIs the output of a cell; bl0werIs an offset value.
4. The method for constructing the medical sensing data flow classification model according to claim 2, wherein a deep separable convolution network including a plurality of convolution layers is arranged inside each cell of the LSTM layer; the convolutional layers include two types: 3 x 3Depth-wise convolutional layers and 1 x 1 convolutional layers, wherein the two types of convolutional layers are arranged at intervals, and a batch standardized BN layer and a ReLU activation layer are connected behind each convolutional layer.
5. The method for constructing the medical sensing data flow classification model according to claim 1, wherein the method classifies whether the predicted time-series data is abnormal or not, and specifically comprises the following steps:
due to n predicted time series data { x1,…,xnThere are m digital signals for each data sample
Figure FDA0002666227480000013
And, the ith predicted time-series data xi∈xn
Let the true value of the n time-series data be
Figure FDA0002666227480000021
The error of the jth element in the ith time-series data is
Figure FDA0002666227480000022
Defining time series data x for multivariate Gaussian ith predictioniError vector e ofiThe distribution p of (A) is:
Figure FDA0002666227480000023
wherein
Figure FDA0002666227480000024
Is an n x 1 vector and is,
Figure FDA0002666227480000025
is an n × n matrix;
if p (e)i(ii) a Mu; xi is less, then called xiIs a normal time series data, otherwise, xiIs anomalous time series data, in which is an error threshold.
6. The method for constructing the medical sensing data flow classification model according to claim 5, characterized in that the method further comprises a conventional segmentation removal method for the acquired human sensing data flow.
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Application publication date: 20210105