CN112022997A - Acupoint application medicine for treating insomnia and preparation method thereof - Google Patents
Acupoint application medicine for treating insomnia and preparation method thereof Download PDFInfo
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- 239000003814 drug Substances 0.000 title claims abstract 19
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 title claims abstract 13
- 206010022437 insomnia Diseases 0.000 title claims abstract 13
- 238000002360 preparation method Methods 0.000 title claims abstract 3
- 239000000284 extract Substances 0.000 claims abstract 10
- 239000000203 mixture Substances 0.000 claims abstract 7
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract 5
- 239000002994 raw material Substances 0.000 claims abstract 5
- 239000010135 fructus aurantii immaturus Substances 0.000 claims abstract 2
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims 12
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims 12
- 241000724115 Ziziphus lotus Species 0.000 claims 12
- 239000000843 powder Substances 0.000 claims 9
- 238000002156 mixing Methods 0.000 claims 8
- 244000131316 Panax pseudoginseng Species 0.000 claims 4
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims 4
- 229910052956 cinnabar Inorganic materials 0.000 claims 4
- 239000000706 filtrate Substances 0.000 claims 4
- 238000010438 heat treatment Methods 0.000 claims 4
- 238000010992 reflux Methods 0.000 claims 4
- 244000183685 Citrus aurantium Species 0.000 claims 3
- 235000007716 Citrus aurantium Nutrition 0.000 claims 3
- 241001080798 Polygala tenuifolia Species 0.000 claims 3
- 239000011159 matrix material Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 238000001704 evaporation Methods 0.000 claims 2
- 238000000605 extraction Methods 0.000 claims 2
- 238000001914 filtration Methods 0.000 claims 2
- 239000012535 impurity Substances 0.000 claims 2
- 240000008866 Ziziphus nummularia Species 0.000 claims 1
- 238000007605 air drying Methods 0.000 claims 1
- 238000004140 cleaning Methods 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 239000012467 final product Substances 0.000 claims 1
- 238000000227 grinding Methods 0.000 claims 1
- 238000010298 pulverizing process Methods 0.000 claims 1
- 238000007789 sealing Methods 0.000 claims 1
- 229940099259 vaseline Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 206010059866 Drug resistance Diseases 0.000 abstract 1
- 235000003143 Panax notoginseng Nutrition 0.000 abstract 1
- 241000180649 Panax notoginseng Species 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 231100000957 no side effect Toxicity 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 239000012466 permeate Substances 0.000 abstract 1
- 239000011505 plaster Substances 0.000 abstract 1
- 210000000582 semen Anatomy 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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Abstract
The invention relates to an acupoint application medicine for treating insomnia and a preparation method thereof. The patch medicine comprises Cinnabaris, Succinum, Notoginseng radix, fructus Aurantii Immaturus, semen Ziziphi Spinosae, lignum Aquilariae Resinatum, Poria, rhizoma Acori Graminei, radix Curcumae, cortex et radix Polygalae, and artificial herba Saussureae Involueratae extract. The raw materials of the plaster medicine are subjected to organic combination dialectical compatibility, and the medicine is applied to Yongquan acupoint, Shenque acupoint and Anmian acupoint, so that the medicine smell permeates channels and collaterals and blood vessels through the acupoints to run the whole body, regulate the functions of organs, play the roles of regulating qi and blood, regulating intestines and stomach and tranquilizing and allaying excitement, and further achieve the effect of curing insomnia; the traditional Chinese medicine composition has the advantages of simple and convenient treatment means, quick response, no drug resistance, strong safety, no side effect, no stimulation and good cure rate.
Description
Technical Field
The invention belongs to the field of traditional Chinese medicines, and particularly relates to an acupoint application medicine for treating insomnia and a preparation method thereof.
Background
Insomnia refers to a condition of poor sleep for a long time, difficulty in falling asleep, early awakening or inability to fall asleep after waking. The main causes of the disease in general are: deficiency of qi and blood, improper diet, mental stress, mental strain, anxiety, excessive smoking and drinking, high stress, pain, anxiety, excitation, time difference, and operation.
At present, methods for treating insomnia at home and abroad are more, such as western medicine treatment and Chinese medicine treatment. But it is difficult to achieve satisfactory results in terms of cure rate and therapeutic means.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides an acupoint application medicine for treating insomnia and a preparation method thereof. The raw materials of the plaster medicine are subjected to organic combination dialectical compatibility, and the medicine is applied to Yongquan acupoint, Shenque acupoint and Anmian acupoint, so that the medicine smell permeates channels and collaterals and blood vessels through the acupoints to run the whole body, regulate the functions of organs, play the roles of regulating qi and blood, regulating intestines and stomach and tranquilizing and allaying excitement, and further achieve the effect of curing insomnia; the traditional Chinese medicine composition has the advantages of simple and convenient treatment means, quick response, no drug resistance, strong safety, no side effect, no stimulation and good cure rate.
The invention provides an acupoint application medicine for treating insomnia, which comprises cinnabar, amber, pseudo-ginseng, immature bitter orange, spina date seed, agilawood, poria with hostwood, rhizoma acori graminei, radix curcumae, polygala tenuifolia and artificial snow lotus herb extracts.
Preferably, the acupoint application medicine for treating insomnia comprises the following raw materials in parts by weight: 1-12 parts of cinnabar, 1-12 parts of amber, 3-18 parts of pseudo-ginseng, 3-18 parts of immature bitter orange, 3-18 parts of spina date seed, 3-18 parts of agilawood, 3-18 parts of poria with hostwood, 3-18 parts of rhizoma acori graminei, 3-18 parts of radix curcumae, 2-12 parts of polygala tenuifolia and 2-12 parts of artificial snow lotus herb extract.
Preferably, the acupoint application medicine for treating insomnia comprises the following raw materials in parts by weight: 6 parts of cinnabar, 6 parts of amber, 10 parts of pseudo-ginseng, 10 parts of immature bitter orange, 10 parts of spina date seed, 10 parts of agilawood, 10 parts of poria with hostwood, 10 parts of rhizoma acori graminei, 10 parts of radix curcumae, 7 parts of polygala tenuifolia and 7 parts of artificial snow lotus herb extract.
Preferably, the preparation method of the artificial snow lotus herb extract comprises the following steps:
(1) cleaning and air drying the artificial snow lotus herb to obtain clean artificial snow lotus herb;
(2) mixing the clean artificial snow lotus herb obtained in the step (1) with water, heating, refluxing and extracting, and filtering to obtain primary filtrate and primary filter residue after completion;
(3) mixing the primary filter residue obtained in the step (2) with ethanol, heating, refluxing and extracting, and filtering to obtain secondary filtrate and secondary filter residue;
(4) and mixing the primary filtrate and the secondary filtrate, and sequentially concentrating and evaporating to dryness to obtain the artificial snow lotus herb extract.
Preferably, in the step (2), the heating temperature is 85-90 ℃; the reflux extraction time is 2-4 h.
Preferably, in the step (3), the heating temperature is 66-70 ℃; the reflux extraction time is 3-5 h.
Preferably, the temperature for evaporating is 40-50 ℃.
In another aspect of the present invention, there is provided a method for preparing the acupoint application medicine for treating insomnia, comprising the steps of:
(i) drying all the raw materials to obtain dried raw materials;
(ii) removing impurities from lignum Aquilariae Resinatum, rhizoma Acori Graminei, fructus Aurantii Immaturus, radix Curcumae, and cortex et radix Polygalae, pulverizing, and mixing to obtain pulverized mixture a; removing impurities from pseudo-ginseng, cinnabar, amber and poria with hostwood, and then crushing and mixing to obtain a crushed mixture b; crushing spina date seeds to obtain spina date seed powder; further grinding the artificial lotus extract to obtain artificial lotus extract powder;
(iii) mixing the crushed mixture a, the crushed mixture b, the spina date seed powder and the artificial lotus flower extract powder to obtain medicine powder; mixing Chinese liquor, succus Zingiberis recens, Mel, and vaseline to obtain transdermal matrix;
(iv) mixing the medicinal powder and transdermal matrix, and sealing to obtain the final product.
Preferably, in the step (ii), the crushed mixture a is 90-100 meshes; the crushed mixture b is 110-120 meshes; the wild jujube kernel powder is 70-80 meshes; the powder of the artificial lotus flower extract is 180-200 meshes.
Preferably, in the step (iv), the weight ratio of the medicine powder to the transdermal matrix is 3-10: 5-18.
The invention further provides a use method of the acupoint application medicine for treating insomnia, which comprises the following steps: the application method comprises applying the patch to SHENQUE acupoint, YONGQUAN acupoint, and hypnotic acupoint 1 hr before sleeping every night, and fixing with adhesive plaster for 1 day.
In order to facilitate an understanding of the present invention, the materials and functions of the present invention will be further described below.
Cinnabar: sweet in taste and slightly cold in nature; heart meridian entered; has effects in clearing away heart-fire, relieving convulsion, tranquilizing mind, and removing toxic materials; it is often used to treat palpitation, insomnia, dreaminess, epilepsy, mania, etc.
Amber: sweet in taste and neutral in nature; the heart, liver and small intestine meridians entered; has tranquilizing and diuretic effects; it is often used to treat infantile convulsion, epilepsy, palpitation, insomnia, stranguria with blood, hematuria, etc.
Pseudo-ginseng: sweet, slightly bitter and warm in nature; entering liver and stomach meridians; has effects in removing blood stasis and relieving swelling; it is often used to treat bleeding, traumatic injury, swelling and pain.
Immature bitter orange: bitter, pungent and sour in flavor, slightly cold in nature; spleen and stomach meridians entered; has effects in removing blood stasis and relieving swelling; it is often used to treat stagnation in the interior, phlegm stagnation and qi stagnation.
Wild jujube seed: sweet in taste and neutral in nature; the heart, spleen, liver and gallbladder meridians are entered; has effects in nourishing liver, calming heart, tranquilizing mind, and arresting sweating; it is often used to treat restlessness, insomnia, palpitation, polydipsia, sweating due to debility, etc.
Agilawood: pungent and bitter taste, slightly warm in nature; spleen, stomach and kidney meridians entered; has effects in promoting qi circulation, relieving pain, warming middle warmer, relieving vomit, and relieving asthma; it is used to treat chest and abdomen distention, pain, stomach cold, emesis, singultus, deficiency of the kidney, reversed flow of qi, and dyspnea.
Poria with hostwood: sweet and light taste, mild in nature; heart and spleen meridians entered; has effects in promoting diuresis, eliminating dampness, invigorating spleen, invigorating qi, calming heart, and tranquilizing mind; it is often used to treat palpitation, amnesia, insomnia, epilepsy, dysuria, etc. due to heart deficiency.
Grassleaf sweelflag rhizome: pungent and bitter in flavor, warm in nature, entering heart and stomach meridians; has effects in regulating qi, inducing resuscitation, promoting blood circulation, and dispelling pathogenic wind; it is often used to treat coma, epilepsy, amnesia, vexation in chest and heart, etc.
Turmeric root-tuber: pungent, bitter and cold in nature; entering liver, heart and lung meridians; has effects in promoting blood circulation, relieving pain, activating qi-flowing, resolving stagnation, clearing away heart-fire, cooling blood, promoting gallbladder function, and eliminating jaundice; it is commonly used to treat stabbing pain in chest and hypochondrium, coma due to fever, epilepsy, mania, etc.
Polygala root: bitter and pungent taste, warm in nature; the heart, kidney and lung meridians are entered; has effects in tranquilizing mind, improving intelligence, eliminating phlegm, and relieving swelling; it is often used to treat palpitation, amnesia, insomnia, etc.
The extract of the artificial snow lotus herb: sweet and bitter taste and warm property; entering liver, spleen and kidney meridians; has antibacterial, blood pressure lowering, tranquilizing, and spasmolytic effects; it is often used to treat impotence, weakness of waist and knees, and rheumatic arthritis.
The invention has the beneficial effects that:
1. the raw materials of the acupoint application medicine for treating insomnia are organically combined and dialectically compatible, and the medicine is applied to Yongquan acupoint, Shenque acupoint and sleeping acupoint, so that the smell of the medicine permeates channels and collaterals and blood vessels through the acupoints to run the whole body, the functions of organs are regulated, the effects of regulating qi and blood, intestines and stomach and tranquilizing and allaying excitement are exerted, and the effect of treating insomnia is achieved.
2. The preparation method of the acupoint application medicine for treating insomnia is simple and convenient to operate, has easily-controlled process, and is beneficial to large-scale production.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
Example 1
The embodiment provides a preparation method of an acupoint application medicine for treating insomnia, which comprises the following steps:
(I) the preparation method of the artificial snow lotus herb extract comprises the following steps:
(1) cleaning and air drying the artificial snow lotus herb to obtain clean artificial snow lotus herb;
(2) mixing the clean artificial snow lotus herb obtained in the step (1) with water, heating at 85 ℃, performing reflux extraction for 2 hours, and filtering to obtain primary filtrate and primary filter residue after completion;
(3) mixing the primary filter residue obtained in the step (2) with ethanol, heating at 66 ℃, performing reflux extraction for 3 hours, and filtering to obtain secondary filtrate and secondary filter residue;
(4) mixing the primary filtrate and the secondary filtrate, sequentially concentrating, and evaporating at 40 deg.C to obtain artificial herba Saussureae Involueratae extract.
(II) preparing the acupoint application medicine for treating insomnia, which comprises the following steps:
(i) drying all the raw materials until the water content is below 7 percent to obtain dried raw materials;
(ii) removing impurities from 3g of agilawood, 3g of rhizoma acori graminei, 3g of fructus aurantii immaturus, 3g of radix curcumae and 2g of polygala tenuifolia, crushing, mixing, and sieving by a 90-mesh sieve to obtain a crushed mixture a; removing impurities from 3g of pseudo-ginseng, 1g of cinnabar, 1g of amber and 3g of poria with hostwood, crushing and mixing, and screening by a 110-mesh screen to obtain a crushed mixture b; crushing 3g of spina date seeds, and screening the crushed spina date seeds with a 70-mesh screen to obtain spina date seed powder; further grinding 2g of the artificial lotus extract, and sieving the ground artificial lotus extract with a 180-mesh sieve to obtain artificial lotus extract powder;
(iii) mixing the crushed mixture a, the crushed mixture b, the spina date seed powder and the artificial lotus flower extract powder to obtain medicine powder; mixing Chinese liquor, succus Zingiberis recens, Mel, and vaseline to obtain transdermal matrix;
(iv) the medicine powder and the transdermal matrix are uniformly mixed and sealed according to the weight ratio of 3:5 to obtain the application medicine.
Example 2
The embodiment provides a preparation method of an acupoint application medicine for treating insomnia, which comprises the following steps:
(I) the preparation method of the artificial snow lotus herb extract comprises the following steps:
(1) cleaning and air drying the artificial snow lotus herb to obtain clean artificial snow lotus herb;
(2) mixing the clean artificial snow lotus herb obtained in the step (1) with water, heating at 90 ℃, performing reflux extraction for 4 hours, and filtering to obtain primary filtrate and primary filter residue after completion;
(3) mixing the primary filter residue obtained in the step (2) with ethanol, heating at 70 ℃, performing reflux extraction for 5 hours, and filtering to obtain secondary filtrate and secondary filter residue;
(4) mixing the primary filtrate and the secondary filtrate, sequentially concentrating, and evaporating at 50 deg.C to obtain herba Saussureae Involueratae extract.
(II) preparing the acupoint application medicine for treating insomnia, which comprises the following steps:
(i) drying all the raw materials until the water content is below 6 percent to obtain dried raw materials;
(ii) removing impurities from 18g of agilawood, 18g of rhizoma acori graminei, 18g of fructus aurantii immaturus, 18g of radix curcumae and 12g of radix polygalae, crushing, mixing, and sieving by a 100-mesh sieve to obtain a crushed mixture a; removing impurities from 18g of pseudo-ginseng, 12g of cinnabar, 12g of amber and 18g of poria with hostwood, crushing and mixing, and sieving with a 120-mesh sieve to obtain a crushed mixture b; crushing 18g of spina date seeds, and screening the crushed spina date seeds with a 80-mesh screen to obtain spina date seed powder; further grinding 12g of artificial lotus extract, and sieving with a 200-mesh sieve to obtain artificial lotus extract powder;
(iii) mixing the crushed mixture a, the crushed mixture b, the spina date seed powder and the artificial lotus flower extract powder to obtain medicine powder; mixing Chinese liquor, succus Zingiberis recens, Mel, and vaseline to obtain transdermal matrix;
(iv) the medicine powder and the transdermal matrix are evenly mixed and sealed according to the weight ratio of 10:18, and the applied medicine is obtained.
Example 3
The embodiment provides a preparation method of an acupoint application medicine for treating insomnia, which comprises the following steps:
(I) the preparation method of the artificial snow lotus herb extract comprises the following steps:
(1) cleaning and air drying the artificial snow lotus herb to obtain clean artificial snow lotus herb;
(2) mixing the clean artificial snow lotus herb obtained in the step (1) with water, heating at 88 ℃, carrying out reflux extraction for 3 hours, and filtering to obtain primary filtrate and primary filter residue after completion;
(3) mixing the primary filter residue obtained in the step (2) with ethanol, heating at 68 ℃, performing reflux extraction for 4 hours, and filtering to obtain secondary filtrate and secondary filter residue;
(4) mixing the primary filtrate and the secondary filtrate, sequentially concentrating, and evaporating at 45 deg.C to obtain artificial herba Saussureae Involueratae extract.
(II) preparing the acupoint application medicine for treating insomnia, which comprises the following steps:
(i) drying all the raw materials until the water content is below 7 percent to obtain dried raw materials;
(ii) removing impurities from 10g of agilawood, 10g of rhizoma acori graminei, 10g of fructus aurantii immaturus, 10g of radix curcumae and 7g of polygala tenuifolia, crushing, mixing, and sieving by a 90-mesh sieve to obtain a crushed mixture a; removing impurities from 10g of pseudo-ginseng, 6g of cinnabar, 6g of amber and 10g of poria with hostwood, crushing and mixing, and screening by a 110-mesh screen to obtain a crushed mixture b; crushing 10g of spina date seeds, and screening the crushed spina date seeds with a 70-mesh screen to obtain spina date seed powder; further grinding 7g of artificial lotus extract, and sieving with a 180-mesh sieve to obtain artificial lotus extract powder;
(iii) mixing the crushed mixture a, the crushed mixture b, the spina date seed powder and the artificial lotus flower extract powder to obtain medicine powder; mixing Chinese liquor, succus Zingiberis recens, Mel, and vaseline to obtain transdermal matrix;
(iv) the medicine powder and the transdermal matrix are evenly mixed and sealed according to the weight ratio of 6:11, and the pasting medicine is obtained.
In order to verify the effect of the acupoint application medicine for treating insomnia, 100 cases are selected for testing, and the application of the medicine for 10 days is 1 course of treatment. The effect is divided into 3 grades which are respectively:
and (3) curing: the insomnia symptoms disappear completely;
improvement: partial disappearance of insomnia symptoms;
and (4) invalidation: after 1 course of administration, the symptoms of insomnia disappear.
The final effect is as follows: 100 cases of medicaments are applied to acupuncture points for treating insomnia, 89 cases are cured, 11 cases are improved, and 0 case is ineffective; the cure rate is 89%, and the effective rate is 100%.
In addition, the following typical cases were selected for specifically explaining the effects.
Case 1:
chengji, female, 57 years old; the application of the patch medicine provided by the invention has the advantages that the application is difficult to fall asleep all the time, three o' clock at night is used for waking up early, the sleep cannot be realized any more, and the women are always troubled by intractable insomnia, and the application has no obvious improvement after taking countless medicines.
Case 2:
liber, male, 47 years old; since the initiation of business in 2007, the pressure of mr. plum is always high, which causes difficulty in falling asleep every day, incapability of working in the daytime, severe alopecia, and eating of a lot of insomnia medicines without improvement. The application of the medicine of the invention for two courses of treatment is greatly improved, and the medicine is continuously applied for one course of treatment to heal the disease.
Case 3:
zhangiao, female, age 68; the insomnia is caused by the insomnias for 10 years, the insomnias are controlled by taking the insomnia medicines, the health is seriously influenced by taking the insomnia medicines for a long time, and the treatment effect is poor due to the traditional Chinese medicine fumigation and washing, acupuncture and moxibustion and medicine treatment, so that the problem of the insomnia cannot be solved. The application of the medicine of the invention for 5 days can achieve good improvement, the acupoint application is continued for 25 days, the recovery is complete, and the relapse does not occur in half a year of follow-up visit.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (10)
1. An acupoint application medicine for treating insomnia is characterized by comprising cinnabar, amber, pseudo-ginseng, immature bitter orange, spina date seed, agilawood, poria with hostwood, rhizoma acori graminei, radix curcumae, polygala tenuifolia and artificial snow lotus herb extract.
2. The acupoint application medicine for treating insomnia according to claim 1, which comprises the following raw materials in parts by weight: 1-12 parts of cinnabar, 1-12 parts of amber, 3-18 parts of pseudo-ginseng, 3-18 parts of immature bitter orange, 3-18 parts of spina date seed, 3-18 parts of agilawood, 3-18 parts of poria with hostwood, 3-18 parts of rhizoma acori graminei, 3-18 parts of radix curcumae, 2-12 parts of polygala tenuifolia and 2-12 parts of artificial snow lotus herb extract.
3. The acupoint application medicine for treating insomnia according to claim 2, which comprises the following raw materials in parts by weight: 6 parts of cinnabar, 6 parts of amber, 10 parts of pseudo-ginseng, 10 parts of immature bitter orange, 10 parts of spina date seed, 10 parts of agilawood, 10 parts of poria with hostwood, 10 parts of rhizoma acori graminei, 10 parts of radix curcumae, 7 parts of polygala tenuifolia and 7 parts of artificial snow lotus herb extract.
4. The acupoint application medicine for treating insomnia according to any one of claims 1 to 3, wherein the preparation method of the artificial snow lotus herb extract comprises the following steps:
(1) cleaning and air drying the artificial snow lotus herb to obtain clean artificial snow lotus herb;
(2) mixing the clean artificial snow lotus herb obtained in the step (1) with water, heating, refluxing and extracting, and filtering to obtain primary filtrate and primary filter residue after completion;
(3) mixing the primary filter residue obtained in the step (2) with ethanol, heating, refluxing and extracting, and filtering to obtain secondary filtrate and secondary filter residue;
(4) and mixing the primary filtrate and the secondary filtrate, and sequentially concentrating and evaporating to dryness to obtain the artificial snow lotus herb extract.
5. The medicine for acupoint application for treating insomnia according to claim 4, wherein in the step (2), the heating temperature is 85-90 ℃; the reflux extraction time is 2-4 h.
6. The acupoint application medicine for treating insomnia according to claim 4, wherein in the step (3), the heating temperature is 66-70 ℃; the reflux extraction time is 3-5 h.
7. The acupoint application medicine for treating insomnia according to claim 4, wherein the temperature for evaporating to dryness in step (4) is 40-50 ℃.
8. The method for preparing the acupoint application medicine for treating insomnia as claimed in any one of claims 1 to 3, which is characterized by comprising the following steps:
(i) drying all the raw materials to obtain dried raw materials;
(ii) removing impurities from lignum Aquilariae Resinatum, rhizoma Acori Graminei, fructus Aurantii Immaturus, radix Curcumae, and cortex et radix Polygalae, pulverizing, and mixing to obtain pulverized mixture a; removing impurities from pseudo-ginseng, cinnabar, amber and poria with hostwood, and then crushing and mixing to obtain a crushed mixture b; crushing spina date seeds to obtain spina date seed powder; further grinding the artificial lotus extract to obtain artificial lotus extract powder;
(iii) mixing the crushed mixture a, the crushed mixture b, the spina date seed powder and the artificial lotus flower extract powder to obtain medicine powder; mixing Chinese liquor, succus Zingiberis recens, Mel, and vaseline to obtain transdermal matrix;
(iv) mixing the medicinal powder and transdermal matrix, and sealing to obtain the final product.
9. The method for preparing an acupoint application medicament for treating insomnia according to claim 8, wherein in step (ii), the pulverized mixture a is 90-100 mesh; the crushed mixture b is 110-120 meshes; the wild jujube kernel powder is 70-80 meshes; the powder of the artificial lotus flower extract is 180-200 meshes.
10. The method for preparing an acupoint application medicament for treating insomnia according to claim 8, wherein in the step (iv), the weight ratio of the medicament powder to the transdermal matrix is 3-10: 5-18.
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Application publication date: 20201204 |