CN111989341B - 结合tim-3的抗体及其用途 - Google Patents
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- CN111989341B CN111989341B CN201980024966.XA CN201980024966A CN111989341B CN 111989341 B CN111989341 B CN 111989341B CN 201980024966 A CN201980024966 A CN 201980024966A CN 111989341 B CN111989341 B CN 111989341B
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Abstract
Description
抗体# | Ka(M-1S-1) | Kd(S-1) | KD(M) |
TIM3-6.10 | 2.02E+05 | 4.15E-04 | 2.05E-09 |
TIM3-6.11 | 2.30E+05 | 3.44E-04 | 1.50E-09 |
TIM3-6.12 | 2.23E+05 | 3.70E-04 | 1.66E-09 |
Claims (39)
Priority Applications (1)
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CN202310550495.4A CN116789827A (zh) | 2018-04-12 | 2019-04-11 | 应用tim-3结合抗体治疗疾病的方法 |
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US201862656358P | 2018-04-12 | 2018-04-12 | |
US62/656,358 | 2018-04-12 | ||
PCT/CN2019/082318 WO2019196911A1 (en) | 2018-04-12 | 2019-04-11 | Antibody binding tim-3 and use thereor |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103079644A (zh) * | 2010-06-11 | 2013-05-01 | 协和发酵麒麟株式会社 | 抗tim-3抗体 |
CN107405397A (zh) * | 2014-10-27 | 2017-11-28 | 新加坡科技研究局 | 抗tim‑3抗体 |
CN107922484A (zh) * | 2015-03-06 | 2018-04-17 | 索伦托治疗有限公司 | 结合tim3的抗体治疗剂 |
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JOP20200096A1 (ar) * | 2014-01-31 | 2017-06-16 | Children’S Medical Center Corp | جزيئات جسم مضاد لـ tim-3 واستخداماتها |
US20160200815A1 (en) * | 2015-01-05 | 2016-07-14 | Jounce Therapeutics, Inc. | Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof |
MA41867A (fr) | 2015-04-01 | 2018-02-06 | Anaptysbio Inc | Anticorps dirigés contre l'immunoglobuline de cellule t et protéine 3 de mucine (tim-3) |
WO2017031242A1 (en) | 2015-08-20 | 2017-02-23 | Sutro Biopharma, Inc. | Anti-tim-3 antibodies, compositions comprising anti-tim-3 antibodies and methods of making and using anti-tim-3 antibodies |
JP2019500893A (ja) | 2015-11-03 | 2019-01-17 | ヤンセン バイオテツク,インコーポレーテツド | Pd−1及びtim−3に特異的に結合する抗体及びそれらの使用 |
CA3020647A1 (en) * | 2016-04-12 | 2017-10-19 | Symphogen A/S | Anti-tim-3 antibodies and compositions |
BR112018074463A2 (pt) * | 2016-05-27 | 2019-03-06 | Agenus Inc. | anticorpos anti-tim-3 e métodos de uso dos mesmos. |
UY37325A (es) * | 2016-07-14 | 2018-01-31 | Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware | Anticuerpos monoclonales que se enlazan a tim3 para estimular respuestas inmunitarias y composiciones que los contienen |
JOP20190013A1 (ar) | 2016-08-25 | 2019-01-31 | Lilly Co Eli | أجسام مضادة لـ (تي آي ام -3) |
CN116655790A (zh) | 2016-08-26 | 2023-08-29 | 百济神州有限公司 | 抗tim-3抗体及其用途 |
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- 2019-04-11 WO PCT/CN2019/082318 patent/WO2019196911A1/en active Application Filing
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103079644A (zh) * | 2010-06-11 | 2013-05-01 | 协和发酵麒麟株式会社 | 抗tim-3抗体 |
CN107405397A (zh) * | 2014-10-27 | 2017-11-28 | 新加坡科技研究局 | 抗tim‑3抗体 |
CN107922484A (zh) * | 2015-03-06 | 2018-04-17 | 索伦托治疗有限公司 | 结合tim3的抗体治疗剂 |
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CN111989341A (zh) | 2020-11-24 |
US20210221885A1 (en) | 2021-07-22 |
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