CN111569037A - Moxibustion liquid traditional Chinese medicine composition, preparation method and self-heating moxibustion patch - Google Patents

Moxibustion liquid traditional Chinese medicine composition, preparation method and self-heating moxibustion patch Download PDF

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Publication number
CN111569037A
CN111569037A CN202010537497.6A CN202010537497A CN111569037A CN 111569037 A CN111569037 A CN 111569037A CN 202010537497 A CN202010537497 A CN 202010537497A CN 111569037 A CN111569037 A CN 111569037A
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China
Prior art keywords
moxibustion
liquid
traditional chinese
chinese medicine
medicine composition
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CN202010537497.6A
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Chinese (zh)
Inventor
高永学
王明芳
段锋彦
董军
陈爱琴
徐宁宁
徐桃娟
陈小明
后晓勤
张虎
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Gansu Minzhou Kangyang Pharmaceutical Technology Co ltd
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Gansu Minzhou Kangyang Pharmaceutical Technology Co ltd
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Priority to CN202010537497.6A priority Critical patent/CN111569037A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
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    • A61K35/648—Myriapods, e.g. centipedes or millipedes
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
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    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention belongs to the technical field of traditional Chinese medicine preparation, and discloses a moxibustion liquid traditional Chinese medicine composition, a preparation method and a self-heating moxibustion plaster, wherein the moxibustion liquid is prepared by processing 16 rare Chinese herbal medicines containing folium artemisiae argyi and the like by applying the principle of moxibustion in the traditional Chinese medicine ancient meridian theory, the moxibustion liquid is coated on corresponding acupuncture points or pathological changes and other parts, any part can be conveniently coated, and then the medicine-coated skin surface is coated by a self-heating bag, the heating bag can be used for heating to achieve the effects similar to that of traditional moxibustion, and can dredge channels and collaterals, regulate yin and yang, promote the liquid medicine to be absorbed and permeated through skin muscle through skin, make the medicine potency reach focus directly, treat the diseases by the functions of traditional moxibustion, local hot compress and promotion of percutaneous absorption of the liquid medicine, the moxibustion device aims to solve the problems that the existing moxibustion uses fire for fumigation moxibustion, which may cause the stimulation of scalding and smoke and the environmental pollution, and the problem that moxibustion cannot be performed when some parts of moxa columns are ignited.

Description

Moxibustion liquid traditional Chinese medicine composition, preparation method and self-heating moxibustion patch
Technical Field
The invention belongs to the technical field of traditional Chinese medicine preparation, and particularly relates to a moxibustion liquid traditional Chinese medicine composition, a preparation method and a self-heating moxibustion patch.
Background
At present: moxibustion, a moxibustion method in acupuncture therapy of traditional Chinese medicine, is a treatment method which uses moxa columns made of folium artemisiae argyi to ignite to generate heat to stimulate acupuncture points or specific parts on the body surface and regulate the physiological and biochemical functions of human body disorder by exciting the activity of meridian qi, thereby achieving the purpose of preventing and treating diseases.
The traditional moxibustion is a fumigation moxibustion method by igniting moxa cones, so that the heat reaches the muscle layer deeply, warms qi and promotes blood circulation. The moxibustion has the effects of warming and dredging channels and collaterals, dispelling cold and removing dampness, regulating qi and blood, and relieving arthralgia and pain. However, as moxibustion is smoked by fire, local skin scalding may be caused due to carelessness of moxibustion application, professionals cannot leave patients to observe that moxibustion is finished in the moxibustion application process, moxa columns at some parts cannot be stably placed or people such as skin thinness, few muscles, large blood vessels and facial parts are not suitable or inconvenient for moxibustion application, and chronic pain patients often like to try to treat or relieve lumbocrural pain by using methods such as plaster application and the like, moxibustion and moxibustion methods and operation need relatively professional technologies, so that the practical popularization rate is greatly reduced. In addition, the existing moxibustion method mainly adopts fire fumigation moxibustion, which may cause the problems of scalding, stimulation of smoke and environmental pollution, and the problem that moxibustion cannot be performed due to the ignition of moxa columns at certain parts.
Through the above analysis, the problems and defects of the prior art are as follows: (1) patients with chronic pain often like to try to treat or relieve waist and leg pain by using a method of applying plaster by themselves, and the moxibustion and moxibustion method and operation need relatively professional techniques, so that the practical popularization rate is greatly reduced.
(2) The existing moxibustion method can cause the problems of scalding, stimulation of smoke and environmental pollution, and the problem that moxibustion cannot be applied when moxa pillars are ignited at certain parts.
(3) According to the existing moxibustion method, as long as a single Chinese mugwort leaf herb is ignited to heat, relax tendons and activate collaterals, the moxibustion essential oil is compatible with monarch, minister, assistant and guide combination of a traditional Chinese medicine formula, and the treatment effect of relaxing tendons and activating collaterals is further improved by heating and promoting absorption through a heating patch.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides a moxibustion liquid traditional Chinese medicine composition, a preparation method and a self-heating moxibustion patch
The moxibustion liquid traditional Chinese medicine composition is prepared from 50-85g of folium artemisiae argyi, 30-60g of angelica sinensis, 30-60g of astragalus membranaceus, 30-55g of sambucus chinensis, 15-45g of rhizoma corydalis, 15-48g of pseudo-ginseng, 9-22g of achyranthes bidentata, 10-30g of safflower, 10-30g of ginger, 15-45g of garden balsam stem, 15-35g of caulis spatholobi, 9-15g of cortex acanthopanacis, 10-35g of pawpaw, 9-18g of rhizoma sparganii, 3-6g of centipede and 3-6g of scorpion by mass.
The invention also aims to provide a preparation method of the moxibustion liquid traditional Chinese medicine composition, which comprises the following steps:
step one, putting 30-60g of angelica, 30-60g of astragalus, 30-55g of sambucus chinensis, 9-22g of achyranthes bidentata, 10-30g of safflower, 10-30g of ginger, 15-45g of garden balsam stem, 15-35g of suberect spatholobus stem and 9-15g of acanthopanax bark into 5000ml of clear water, decocting to 1000ml, filtering out residues, and taking 900 ml of filtrate; adding 3000ml of water into the residues, decocting the residues to 600ml again, and taking 500ml of filtrate and 600 ml; mixing the two filtrates to obtain solution 1;
step two, grinding 15-45g of rhizoma corydalis, 15-48g of pseudo-ginseng, 10-35g of pawpaw and 9-18g of rhizoma sparganii into powder to 200 meshes, adding 600ml of water, stirring, decocting for 90 minutes, adding 50-85g of folium artemisiae argyi, continuing to decoct for 30 minutes, filtering residues, and taking filtrate to obtain solution 2;
step three, grinding 3-6g of centipede and 3-6g of scorpion into powder, sieving the powder with a 300-mesh sieve, adding 500ml of 75% alcohol, sealing and soaking for 24 hours, then filtering out residues and taking supernatant filtrate to obtain 3 liquid;
and step four, mixing and shaking the solution 1, the solution 2 and the solution 3 uniformly, and taking supernatant fluid to prepare the moxibustion liquid for later use.
The invention also aims to provide moxibustion essential oil liquid purified by using the moxibustion liquid traditional Chinese medicine composition.
The invention also aims to provide an ointment prepared by using the moxibustion essential oil liquid.
The invention also aims to provide a self-heating moxibustion patch prepared by using the ointment.
By combining all the technical schemes, the invention has the advantages and positive effects that:
the moxibustion liquid provided by the invention not only has the effect of moxibustion, but also has the effect of promoting the effective ingredients of the Chinese herbal medicines to be quickly absorbed by skin, so that the effective ingredients of the Chinese herbal medicines are not absorbed by gastrointestinal tracts, the stimulation to the gastrointestinal tracts is reduced, the moxibustion liquid can be well utilized, and the triple treatment effects of moxibustion treatment, quick absorption of external medicines and hot compress treatment are achieved. Compared with traditional moxibustion, the moxibustion device is more convenient and easy to operate, wide in applicable crowd, reliable in temperature, high in safety and stronger in persistence, and can not scald.
The moxibustion liquid provided by the invention can be pasted on body acupuncture points and pathological change surfaces through the self-heating bag, so that micromolecular active substances are easier to permeate and absorb, and the drug molecules directly reach focus of infection. Relieve spasm of tendon after strain. Dredging blocked capillary vessels, gradually softening and dissolving protruded nucleus pulposus and bony spur of intervertebral disc, relieving nerve compression, fundamentally eliminating compression symptoms, activating human body channels and collaterals, and repairing damaged tissue cells. Improve the blood nutrition supply of tissues, regulate the functions of qi, blood and viscera and achieve the treatment effect of moxibustion.
The moxibustion liquid provided by the invention can be pasted on acupuncture points and pathological change surfaces of a body through the self-heating bag. Adopts a heating physiotherapy transdermal technology, and achieves the effect of treating rehabilitation lesion by skin administration and contact and absorption of human skin and channels and collaterals. The two major links of digestion and absorption and blood circulation are omitted, so that the internal organs are not damaged, the treatment speed is improved, the treatment period is short, and the drug effect is remarkable.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed to be used in the embodiments of the present application will be briefly described below, and it is obvious that the drawings described below are only some embodiments of the present application, and it is obvious for those skilled in the art that other drawings can be obtained from the drawings without creative efforts.
FIG. 1 is a flow chart of a preparation method of a moxibustion liquid traditional Chinese medicine composition provided by the embodiment of the invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Aiming at the problems in the prior art, the invention provides a moxibustion liquid traditional Chinese medicine composition, a preparation method and a self-heating moxibustion patch, and the invention is described in detail with reference to the accompanying drawings.
As shown in fig. 1, the preparation method of the moxibustion liquid traditional Chinese medicine composition provided by the embodiment of the invention comprises the following steps:
s101: 30-60g of angelica, 30-60g of astragalus, 30-55g of sambucus chinensis, 9-22g of achyranthes root, 10-30g of safflower, 10-30g of ginger, 15-45g of garden balsam stem, 15-35g of suberect spatholobus stem and 9-15g of acanthopanax bark, putting into 5000ml of clear water, decocting to 1000ml, filtering out residues, and taking 900 ml of filtrate; adding 3000ml of water into the residues, decocting the residues to 600ml again, and taking 500ml of filtrate and 600 ml; mixing the two filtrates to obtain solution 1.
S102: 15-45g of rhizoma corydalis, 15-48g of pseudo-ginseng, 10-35g of pawpaw and 9-18g of rhizoma sparganii are ground into powder of 200 meshes, 600ml of water is added, stirring is carried out, then decoction is carried out for 90 minutes, 50-85g of folium artemisiae argyi is added, decoction is carried out for 30 minutes, residues are filtered, and filtrate is obtained, namely the solution 2.
S103: 3-6g of centipede and 3-6g of scorpion are ground into powder, the powder is sieved by a 300-mesh sieve, 500ml of 75 percent alcohol is added for closed soaking for 24 hours, then the residue is filtered out, and the supernatant is taken to obtain the liquid 3.
S104: mixing solution 1, solution 2 and solution 3, shaking, and collecting supernatant to obtain moxibustion solution.
The present invention will be further described with reference to the following examples.
Example 1 (formulation 1):
the moxibustion liquid traditional Chinese medicine composition provided by the embodiment of the invention consists of 50g of folium artemisiae argyi, 30g of angelica sinensis, 30g of astragalus membranaceus, 30g of herba sambuci chinensis, 15g of rhizoma corydalis, 15g of radix pseudo-ginseng, 9g of radix achyranthis bidentatae, 10g of safflower carthamus, 10g of ginger, 15g of garden balsam stem, 15g of caulis spatholobi, 9g of cortex acanthopanacis, 10g of pawpaw, 9g of rhizoma sparganii, 3g of centipede.
Example 2 (formulation 2)
The moxibustion liquid traditional Chinese medicine composition provided by the embodiment of the invention consists of 75g of folium artemisiae argyi, 45g of angelica sinensis, 50g of astragalus membranaceus, 45g of herba sambuci chinensis, 25g of rhizoma corydalis, 20g of pseudo-ginseng, 15g of radix achyranthis bidentatae, 15g of safflower carthamus, 15g of ginger, 25g of garden balsam stem, 25g of caulis spatholobi, 15g of cortex acanthopanacis, 25g of pawpaw, 13g of rhizoma sparganii, 4g of centipede and.
Example 3 (formulation 3)
The moxibustion liquid traditional Chinese medicine composition provided by the embodiment of the invention consists of 85g of folium artemisiae argyi, 60g of angelica sinensis, 60g of astragalus membranaceus, 55g of sambucus chinensis, 45g of rhizoma corydalis, 48g of pseudo-ginseng, 22g of achyranthes bidentata, 30g of safflower, 30g of ginger, 45g of garden balsam stem, 35g of caulis spatholobi, 12g of acanthopanax, 35g of pawpaw, 18g of rhizoma sparganii, 6g of centipede and 6g of scorpion.
Example 4 (formulation 4)
The moxibustion liquid traditional Chinese medicine composition provided by the embodiment of the invention consists of 65g of folium artemisiae argyi, 35g of angelica sinensis, 35g of astragalus membranaceus, 40g of herba sambuci chinensis, 20g of rhizoma corydalis, 20g of radix notoginseng, 18g of safflower, 18g of ginger, 30g of garden balsam stem, 20g of caulis spatholobi, 10g of cortex acanthopanacis, 15g of pawpaw, 15g of rhizoma sparganii, 5g of centipede and 5g of scorpion.
Example 5 (formulation 5)
The moxibustion liquid traditional Chinese medicine composition provided by the embodiment of the invention consists of 55g of folium artemisiae argyi, 55g of angelica sinensis, 45g of astragalus membranaceus, 32g of rhizoma corydalis, 30g of radix notoginseng, 12g of radix achyranthis bidentatae, 12g of safflower, 20g of ginger, 20g of garden balsam stem, 18g of caulis spatholobi, 13g of cortex acanthopanacis, 20g of pawpaw, 12g of rhizoma sparganii, 4.5g of centipede and 4.5g of scorpion
Example 6 (formulation 6)
The moxibustion liquid traditional Chinese medicine composition provided by the embodiment of the invention consists of 60g of folium artemisiae argyi, 50g of angelica sinensis, 40g of astragalus membranaceus, 35g of rhizoma corydalis, 35g of radix notoginseng, 20g of radix achyranthis bidentatae, 10-30g of safflower, 10-30g of ginger, 15-45g of garden balsam stem, 15-35g of caulis spatholobi, 9-15g of cortex acanthopanacis, 20g of pawpaw, 14g of rhizoma sparganii, 4g of centipede and 4g of scorpion.
To further demonstrate the therapeutic effects of the present invention, the following clinical tests were conducted on the moxibustion solutions prepared in examples 1 to 6, and the results are shown in Table 1:
and (3) healing: clinical symptoms disappear, and the function is normal;
the effect is shown: clinical symptoms basically disappear, the function is basically normal, and the disease symptoms are relieved by more than 90 percent;
the method has the following advantages: clinical symptoms basically disappear, the function is basically normal, and the disease symptoms are relieved by more than 80 percent;
the effect is poor: the clinical symptoms are reduced by about 50 percent.
TABLE 1 results of clinical trials conducted on moxibustion solutions prepared in examples 1 to 6
As can be seen from table 1, the moxibustion liquid prepared from the Chinese medicinal composition of embodiments 1-6 of the present invention has a good therapeutic effect on local pain of women, cold womb, dysmenorrhea, scapulohumeral periarthritis, cervical spondylosis, lumbar disc herniation, and osteoarthritis. And is convenient to use.
The above description is only for the purpose of illustrating the present invention and the appended claims are not to be construed as limiting the scope of the invention, which is intended to cover all modifications, equivalents and improvements that are within the spirit and scope of the invention as defined by the appended claims.

Claims (5)

1. A moxibustion liquid traditional Chinese medicine composition is characterized by comprising, by mass, 50-85g of folium artemisiae argyi, 30-60g of angelica sinensis, 30-60g of astragalus membranaceus, 30-55g of sambucus chinensis, 15-45g of rhizoma corydalis, 15-48g of pseudo-ginseng, 9-22g of achyranthes bidentata, 10-30g of safflower carthamus, 10-30g of ginger, 15-45g of garden balsam stem, 15-35g of caulis spatholobi, 9-15g of cortex acanthopanacis, 10-35g of pawpaw, 9-18g of rhizoma sparganii, 3-6g of centipede and 3-6g of scorpion.
2. A method for preparing the moxibustion liquid traditional Chinese medicine composition as claimed in claim 1, which is characterized in that the preparation method of the moxibustion liquid traditional Chinese medicine composition comprises the following steps:
step one, putting 30-60g of angelica, 30-60g of astragalus, 30-55g of sambucus chinensis, 9-22g of achyranthes bidentata, 10-30g of safflower, 10-30g of ginger, 15-45g of garden balsam stem, 15-35g of suberect spatholobus stem and 9-15g of acanthopanax bark into 5000ml of clear water, decocting to 1000ml, filtering out residues, and taking 900 ml of filtrate; adding 3000ml of water into the residues, decocting the residues to 600ml again, and taking 500ml of filtrate and 600 ml; mixing the two filtrates to obtain solution 1;
step two, grinding 15-45g of rhizoma corydalis, 15-48g of pseudo-ginseng, 10-35g of pawpaw and 9-18g of rhizoma sparganii into powder to 200 meshes, adding 600ml of water, stirring, decocting for 90 minutes, adding 50-85g of folium artemisiae argyi, continuing to decoct for 30 minutes, filtering residues, and taking filtrate to obtain solution 2;
step three, grinding 3-6g of centipede and 3-6g of scorpion into powder, sieving the powder with a 300-mesh sieve, adding 500ml of 75% alcohol, sealing and soaking for 24 hours, then filtering out residues and taking supernatant filtrate to obtain 3 liquid;
and step four, mixing and shaking the solution 1, the solution 2 and the solution 3 uniformly, and taking supernatant fluid to prepare the moxibustion liquid for later use.
3. A moxibustion essential oil liquid purified by using the moxibustion liquid traditional Chinese medicine composition of claim 1.
4. An ointment prepared from the moxibustion essential oil liquid of claim 3.
5. A self-heating moxibustion patch prepared from the ointment of claim 4.
CN202010537497.6A 2020-06-12 2020-06-12 Moxibustion liquid traditional Chinese medicine composition, preparation method and self-heating moxibustion patch Pending CN111569037A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104189399A (en) * 2014-09-22 2014-12-10 郭巧玲 Plaster for treating pain of cervical vertebra, vertebral column, waist and legs and preparation method thereof
CN106620631A (en) * 2017-02-23 2017-05-10 李明忠 Cold and hot-applicable black plaster and preparation method thereof
CN107625944A (en) * 2017-09-29 2018-01-26 南京仙草堂生物科技有限公司 Warm application of a kind of ginger folium artemisiae argyi cervical vertebra and preparation method thereof
CN108186749A (en) * 2018-02-09 2018-06-22 厦门市中萪研生物科技有限公司 Treat Chinese medicine composition of cervical spondylosis and preparation method thereof
CN109125692A (en) * 2018-09-03 2019-01-04 山东晟创生物科技有限公司 A kind of moxibustion liquid and preparation method thereof
CN109589396A (en) * 2018-12-17 2019-04-09 郭宇欣 A kind of Moxa conditioning essential oil and preparation method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104189399A (en) * 2014-09-22 2014-12-10 郭巧玲 Plaster for treating pain of cervical vertebra, vertebral column, waist and legs and preparation method thereof
CN106620631A (en) * 2017-02-23 2017-05-10 李明忠 Cold and hot-applicable black plaster and preparation method thereof
CN107625944A (en) * 2017-09-29 2018-01-26 南京仙草堂生物科技有限公司 Warm application of a kind of ginger folium artemisiae argyi cervical vertebra and preparation method thereof
CN108186749A (en) * 2018-02-09 2018-06-22 厦门市中萪研生物科技有限公司 Treat Chinese medicine composition of cervical spondylosis and preparation method thereof
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