CN111163756B - 氯普鲁卡因的局部制剂 - Google Patents

氯普鲁卡因的局部制剂 Download PDF

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Publication number
CN111163756B
CN111163756B CN201880057219.1A CN201880057219A CN111163756B CN 111163756 B CN111163756 B CN 111163756B CN 201880057219 A CN201880057219 A CN 201880057219A CN 111163756 B CN111163756 B CN 111163756B
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CN
China
Prior art keywords
formulation
weight
chloroprocaine
anesthesia
inducing
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Active
Application number
CN201880057219.1A
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English (en)
Chinese (zh)
Other versions
CN111163756A (zh
Inventor
A·米提蒂利
E·多纳蒂
C·比安奇
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Sintetica SA
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Sintetica SA
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Publication of CN111163756A publication Critical patent/CN111163756A/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201880057219.1A 2017-09-15 2018-09-14 氯普鲁卡因的局部制剂 Active CN111163756B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762559220P 2017-09-15 2017-09-15
US62/559,220 2017-09-15
PCT/IB2018/057073 WO2019053657A1 (en) 2017-09-15 2018-09-14 TOPICAL FORMULATIONS OF CHLOROPROCAINE

Publications (2)

Publication Number Publication Date
CN111163756A CN111163756A (zh) 2020-05-15
CN111163756B true CN111163756B (zh) 2022-04-15

Family

ID=63713967

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880057219.1A Active CN111163756B (zh) 2017-09-15 2018-09-14 氯普鲁卡因的局部制剂

Country Status (22)

Country Link
US (3) US10792271B2 (https=)
EP (1) EP3681473A1 (https=)
JP (1) JP2020533321A (https=)
KR (1) KR102759903B1 (https=)
CN (1) CN111163756B (https=)
AU (1) AU2018332212B2 (https=)
CA (1) CA3070336C (https=)
CL (1) CL2020000665A1 (https=)
CO (1) CO2020002985A2 (https=)
CR (1) CR20200133A (https=)
CU (1) CU20200019A7 (https=)
EA (1) EA202090735A1 (https=)
EC (1) ECSP20022313A (https=)
IL (1) IL273213B2 (https=)
JO (1) JOP20200010A1 (https=)
MA (1) MA50241A (https=)
MX (1) MX2020002898A (https=)
PE (1) PE20201281A1 (https=)
PH (1) PH12020550029A1 (https=)
SG (1) SG11202000992RA (https=)
WO (1) WO2019053657A1 (https=)
ZA (1) ZA202000601B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202139993A (zh) * 2020-03-16 2021-11-01 瑞士商辛鐵堤卡公司 具有經改良之功能性的眼用氯普魯卡因(chloroprocaine)凝膠

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218428B1 (en) * 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
CN101119713A (zh) * 2004-11-24 2008-02-06 阿尔高克斯制药公司 类辣椒素凝胶制剂及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR930000050B1 (ko) * 1990-08-29 1993-01-06 브리스톨-마이어즈 스퀴브 컴페니 항균제 겔 배합물
JP2004123634A (ja) * 2002-10-03 2004-04-22 Lion Corp 眼科用組成物
WO2004058329A2 (en) * 2002-12-20 2004-07-15 The Board Of Trustees Of The Leland Stanford Junior University Ester combination local anesthetic
US20050137177A1 (en) 2003-12-18 2005-06-23 Shafer Steven L. Ester combination local anesthetic
ITMI20051633A1 (it) 2005-09-06 2007-03-07 Sint Sa Nuovo uso di una composizione comprendente cloroprocaina hcl nuova composizione comprendente cloroprocaina hcl e metodo per la sua fabbricazione
ITMI20122120A1 (it) * 2012-12-12 2014-06-13 Sint Sa Composizione farmaceutica a base di cloroprocaina per la somministrazione intratecale ripetuta
CN103405576B (zh) * 2013-08-23 2016-03-30 何学忠 一种治疗由焊接强光辐射引起的眼部疾病的滴眼液

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218428B1 (en) * 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
CN101119713A (zh) * 2004-11-24 2008-02-06 阿尔高克斯制药公司 类辣椒素凝胶制剂及其用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Randomized double-blind study of the clinical duration and efficacy of nesacaine-mpf 2% and 3% in peribulbar anesthesia;GARY CASS等;《JOURNAL CATARACT AND REFRACTIVE SURGERY》;19991231(第12期);摘要 *

Also Published As

Publication number Publication date
EP3681473A1 (en) 2020-07-22
JP2020533321A (ja) 2020-11-19
IL273213B2 (en) 2025-06-01
IL273213B1 (en) 2025-02-01
KR20200053476A (ko) 2020-05-18
AU2018332212A1 (en) 2020-02-27
MX2020002898A (es) 2020-11-06
CA3070336C (en) 2022-08-23
CU20200019A7 (es) 2020-11-30
WO2019053657A1 (en) 2019-03-21
IL273213A (en) 2020-04-30
AU2018332212B2 (en) 2023-03-16
KR102759903B1 (ko) 2025-01-23
US11969403B2 (en) 2024-04-30
EA202090735A1 (ru) 2020-06-22
US20190083446A1 (en) 2019-03-21
US10792271B2 (en) 2020-10-06
BR112020003095A2 (pt) 2020-08-25
CL2020000665A1 (es) 2020-09-21
SG11202000992RA (en) 2020-03-30
JOP20200010A1 (ar) 2020-01-22
CA3070336A1 (en) 2019-03-21
CN111163756A (zh) 2020-05-15
ZA202000601B (en) 2021-02-24
PH12020550029A1 (en) 2021-02-08
CO2020002985A2 (es) 2020-05-29
ECSP20022313A (es) 2020-07-31
US20200390738A1 (en) 2020-12-17
US20240216323A1 (en) 2024-07-04
MA50241A (fr) 2020-07-22
CR20200133A (es) 2020-05-09
PE20201281A1 (es) 2020-11-24

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