CN111035790A - Transparent application for indwelling needle and preparation method thereof - Google Patents
Transparent application for indwelling needle and preparation method thereof Download PDFInfo
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- CN111035790A CN111035790A CN201911300931.2A CN201911300931A CN111035790A CN 111035790 A CN111035790 A CN 111035790A CN 201911300931 A CN201911300931 A CN 201911300931A CN 111035790 A CN111035790 A CN 111035790A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 44
- 241001474374 Blennius Species 0.000 claims abstract description 26
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 26
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 26
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 22
- 239000000843 powder Substances 0.000 claims abstract description 22
- 239000000463 material Substances 0.000 claims description 142
- 238000006243 chemical reaction Methods 0.000 claims description 65
- 239000000203 mixture Substances 0.000 claims description 50
- 239000003431 cross linking reagent Substances 0.000 claims description 18
- 239000003085 diluting agent Substances 0.000 claims description 18
- 239000003365 glass fiber Substances 0.000 claims description 18
- 239000004014 plasticizer Substances 0.000 claims description 18
- 239000004094 surface-active agent Substances 0.000 claims description 18
- 238000000071 blow moulding Methods 0.000 claims description 15
- 238000003860 storage Methods 0.000 claims description 15
- 238000005303 weighing Methods 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 239000008367 deionised water Substances 0.000 claims description 13
- 229910021641 deionized water Inorganic materials 0.000 claims description 13
- 239000000314 lubricant Substances 0.000 claims description 13
- 239000003607 modifier Substances 0.000 claims description 13
- SOQBVABWOPYFQZ-UHFFFAOYSA-N oxygen(2-);titanium(4+) Chemical compound [O-2].[O-2].[Ti+4] SOQBVABWOPYFQZ-UHFFFAOYSA-N 0.000 claims description 13
- 229920013716 polyethylene resin Polymers 0.000 claims description 13
- 238000005520 cutting process Methods 0.000 claims description 10
- 238000007599 discharging Methods 0.000 claims description 10
- 239000006185 dispersion Substances 0.000 claims description 10
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims description 8
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims description 8
- 239000011505 plaster Substances 0.000 claims description 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 6
- 239000002313 adhesive film Substances 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 238000000465 moulding Methods 0.000 claims description 5
- 238000004806 packaging method and process Methods 0.000 claims description 5
- 239000002245 particle Substances 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 5
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 claims description 4
- YDICVVYPXSZSFA-UHFFFAOYSA-N diphenyl propan-2-yl phosphate Chemical compound C=1C=CC=CC=1OP(=O)(OC(C)C)OC1=CC=CC=C1 YDICVVYPXSZSFA-UHFFFAOYSA-N 0.000 claims description 4
- 239000008096 xylene Substances 0.000 claims description 4
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 3
- FUOZJYASZOSONT-UHFFFAOYSA-N 2-propan-2-yl-1h-imidazole Chemical compound CC(C)C1=NC=CN1 FUOZJYASZOSONT-UHFFFAOYSA-N 0.000 claims description 3
- IUNMPGNGSSIWFP-UHFFFAOYSA-N dimethylaminopropylamine Chemical compound CN(C)CCCN IUNMPGNGSSIWFP-UHFFFAOYSA-N 0.000 claims description 3
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 claims description 3
- 125000005456 glyceride group Chemical group 0.000 claims description 3
- 239000000787 lecithin Substances 0.000 claims description 3
- 229940067606 lecithin Drugs 0.000 claims description 3
- 235000010445 lecithin Nutrition 0.000 claims description 3
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 claims description 3
- STCOOQWBFONSKY-UHFFFAOYSA-N tributyl phosphate Chemical compound CCCCOP(=O)(OCCCC)OCCCC STCOOQWBFONSKY-UHFFFAOYSA-N 0.000 claims description 3
- YYQRGCZGSFRBAM-UHFFFAOYSA-N Triclofos Chemical compound OP(O)(=O)OCC(Cl)(Cl)Cl YYQRGCZGSFRBAM-UHFFFAOYSA-N 0.000 claims description 2
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 claims description 2
- 229960001147 triclofos Drugs 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 11
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract description 8
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 8
- 230000008569 process Effects 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 4
- 230000002093 peripheral effect Effects 0.000 abstract description 4
- 239000004408 titanium dioxide Substances 0.000 abstract description 4
- 239000003814 drug Substances 0.000 abstract description 3
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 230000007246 mechanism Effects 0.000 abstract description 2
- 239000011148 porous material Substances 0.000 abstract description 2
- 230000005855 radiation Effects 0.000 abstract description 2
- 238000009423 ventilation Methods 0.000 abstract description 2
- 230000003385 bacteriostatic effect Effects 0.000 abstract 2
- 230000029058 respiratory gaseous exchange Effects 0.000 abstract 1
- 230000006870 function Effects 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 230000003213 activating effect Effects 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 239000000084 colloidal system Substances 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 206010070834 Sensitisation Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 125000001664 diethylamino group Chemical group [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F13/0289—Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of adhesive dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00365—Plasters use
- A61F2013/00412—Plasters use for use with needles, tubes or catheters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1586—Holding accessories for holding infusion needles on the body
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Inorganic Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention discloses a transparent application for an indwelling needle and a preparation method thereof, and relates to the technical field of medical transparent application, wherein calcium carbonate powder, nano-scale titanium dioxide and seaweed carbon are added into the components for preparing the transparent application in the prior art, the calcium carbonate powder is added, so that the whole transparent application has a ventilation function after contacting with the skin of a patient in the using process, the pore breathing of the patient is not influenced in the treatment process, the comfort is improved, the nano-scale titanium dioxide has the antibacterial and bacteriostatic ability, the transparent application can have the antibacterial and bacteriostatic function after being put into use on the transparent application, the seaweed carbon can radiate far infrared rays, and after the transparent application contains the seaweed carbon, the far infrared radiation mechanism generated by the seaweed carbon can promote the blood circulation of the peripheral area of the indwelling needle in the actual use, thereby improving the conveying efficiency and effect of the medicine and improving the practicability.
Description
Technical Field
The invention relates to the technical field of transparent application, in particular to a transparent application for an indwelling needle and a preparation method thereof.
Background
The transparent plaster is an ultrathin and comfortable novel auxiliary material produced by adopting the modern international high and new technology, is a special semipermeable membrane, has the characteristics of good water resistance, mildew resistance, low sensitization, transparency, high elasticity and the like, is widely applied to the fixation of venous and arterial catheters or instruments, can cover and protect skin from being damaged and wound treatment, and is a necessary product for skin beauty protection, family stock medicine chest, military training exercise, wartime field first aid and factory construction places.
However, the transparent application usually used in medical treatment at present has a single function, and the defects mainly include the following:
1. the medical transparent patch has the advantages that in the using process, due to the lack of an antibacterial function, the peripheral area of the indwelling needle cannot be subjected to effective antibacterial treatment after the indwelling needle is inserted into the vein of a patient;
2. the medical transparent patch is pasted with the skin of a patient through a colloid in the using process, so that the air permeability is poor, and the pasting part of the patient has uncomfortable feeling;
3. the medical transparent application plaster can not generate the effect of activating blood circulation to blood in the peripheral area of the indwelling needle in the using process, and has lower practicability.
In conclusion, those skilled in the art have proposed a transparent dressing for an indwelling needle and a method for producing the same.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a transparent application for an indwelling needle and a preparation method thereof, and solves the problems that after the indwelling needle is inserted into a vein of a patient due to lack of an antibacterial function, effective antibacterial treatment cannot be carried out on the area around the indwelling needle, the adhesive is adhered to the skin of the patient through a colloid, the air permeability is poor, the adhered part of the patient feels uncomfortable, the blood activating effect cannot be carried out on the blood in the area around the indwelling needle, and the practicability is low.
In order to achieve the purpose, the invention is realized by the following technical scheme: a transparent plaster for an indwelling needle comprises a main material A and an auxiliary material B,
the main material A comprises deionized water, polyethylene resin, calcium carbonate powder, nano titanium dioxide, glass fiber and seaweed carbon, and is prepared from the following components in parts by weight: 31-45 parts of deionized water, 85-100 parts of polyethylene resin, 32-37 parts of calcium carbonate powder, 17-26 parts of nano titanium dioxide, 8-15 parts of glass fiber and 13-18 parts of seaweed carbon;
the auxiliary material B comprises a diluent, a cross-linking agent, a surfactant, a plasticizer, a modifier and a lubricant, and is prepared from the following components in parts by weight: 11-18 parts of diluent, 5-9 parts of cross-linking agent, 14-20 parts of surfactant, 16-21 parts of plasticizer, 5-9 parts of modifier and 17-23 parts of lubricant.
Preferably, the main material A is prepared from the following components in parts by weight: 45 parts of deionized water, 100 parts of polyethylene resin, 37 parts of calcium carbonate powder, 26 parts of nano titanium dioxide, 15 parts of glass fiber and 18 parts of seaweed carbon;
the auxiliary material B is prepared from the following components in parts by weight: 18 parts of diluent, 9 parts of cross-linking agent, 20 parts of surfactant, 21 parts of plasticizer, 9 parts of modifier and 23 parts of lubricant.
Preferably, the main material A is prepared from the following components in parts by weight: 31 parts of deionized water, 85 parts of polyethylene resin, 32 parts of calcium carbonate powder, 17 parts of nano titanium dioxide, 8 parts of glass fiber and 13 parts of seaweed carbon;
the auxiliary material B is prepared from the following components in parts by weight: 11 parts of diluent, 5 parts of cross-linking agent, 14 parts of surfactant, 16 parts of plasticizer, 5 parts of modifier and 17 parts of lubricant.
Preferably, the main material A is prepared from the following components in parts by weight: 40 parts of deionized water, 90 parts of polyethylene resin, 35 parts of calcium carbonate powder, 25 parts of nano titanium dioxide, 13 parts of glass fiber and 16 parts of seaweed carbon;
the auxiliary material B is prepared from the following components in parts by weight: 14 parts of diluent, 8 parts of cross-linking agent, 18 parts of surfactant, 18 parts of plasticizer, 8 parts of modifier and 21 parts of lubricant.
Preferably, the particle size specification of the calcium carbonate powder is 700-900 meshes, and the glass fiber and the seaweed carbon are both powdery substances.
Preferably, the diluent is one or more of acetone, toluene, xylene and styrene, and the cross-linking agent is one or more of diethylamine, 2-isopropylimidazole and dimethylaminopropylamine.
Preferably, the surfactant is one or more of sodium dodecyl benzene sulfonate, fatty glyceride and lecithin, and the plasticizer is one or more of diphenyl isopropyl phenyl phosphate, trichloroethyl phosphate and tributyl phosphate.
Preferably, the transparent application patch for the indwelling needle is prepared by the following steps:
s1, preparation: preparing an electronic scale, a reaction kettle I, a reaction kettle II, a film stretching machine, a blow molding machine, a dispersion machine and a plurality of material storage cylinders;
s2, weighing the main materials and the auxiliary materials: weighing the weight of each component in the main material A and the auxiliary material B by using an electronic scale, and correspondingly placing the components of the main material A in one storage cylinder and the components of the auxiliary material B in the other storage cylinder for later use after weighing;
s3, preparing a main material A: starting the reaction kettle I, adding all the components of the main material A into the reaction kettle I, adjusting the rotating speed of the reaction kettle I to be 300-0.6 MPa, the pressure intensity to be 0.3-0.6MPa and the temperature to be 23-27 ℃ until the components of the main material A are uniformly mixed, and discharging the main material A from the reaction kettle I for later use;
s4, preparing an auxiliary material B: starting the reaction kettle II, adding all the components of the auxiliary material B into the reaction kettle II, and adjusting the rotating speed of the reaction kettle II to be 200-0.8 MPa, the pressure intensity to be 0.5-0.8MPa and the temperature to be 45-50 ℃ until the components of the auxiliary material B are uniformly mixed;
s5, preparing a mixture of the main material A and the auxiliary material B: adding the main material A prepared in the step S3 into a reaction kettle II, starting the reaction kettle II again, adjusting the rotating speed of the reaction kettle II to be 800-1000r/min, the pressure to be 1.2-1.5MPa and the temperature to be 65-75 ℃ until the main material A and the auxiliary material B are completely mixed, discharging the mixture from the reaction kettle II, standing and cooling the mixture for later use to obtain a mixed material;
s6, dispersing the mixture: putting the mixture prepared in the step S5 into a dispersion machine, and taking out after the mixture is fully dispersed;
s7, stretching the mixture: adding the mixture dispersed in the step S6 into a stretcher, and stretching the mixture;
s8, blow molding: putting the mixture stretched in the step S7 into a blow molding machine, and molding the mixture to obtain a transparent adhesive film;
s9, cutting and packaging: the transparent application film obtained in step S8 is subjected to a cutting process in accordance with the medical specification, and packaged.
Advantageous effects
The invention provides a transparent application for an indwelling needle and a preparation method thereof. Compared with the prior art, the method has the following beneficial effects:
this keep somewhere needle and use transparent application and preparation method thereof, through adding calcium carbonate powder in the composition that has the transparent application of preparation at present, nanometer titanium dioxide and seaweed carbon, calcium carbonate powder's interpolation, let whole transparent application in the use, after contacting with patient's skin, possess ventilation function, let the patient in the treatment process, do not influence the pore and breathe, the comfort is improved, nanometer titanium dioxide self possesses antibiotic antibacterial ability, after putting into use on transparent application, can let transparent application possess antibiotic antibacterial function, and seaweed carbon self can radiate far infrared, after containing seaweed carbon in the transparent application, when in-service use, the far infrared radiation mechanism that seaweed carbon produced, can promote the circulation of keeping somewhere needle peripheral zone blood, and then conveying efficiency and the effect of medicine have been improved.
Drawings
FIG. 1 is a block diagram of a preparation process of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The invention provides a technical scheme that: a transparent plaster for an indwelling needle comprises a main material A and an auxiliary material B,
the main material A is prepared from the following components in parts by weight: 45 parts of deionized water, 100 parts of polyethylene resin, 37 parts of calcium carbonate powder, 26 parts of nano titanium dioxide, 15 parts of glass fiber and 18 parts of seaweed carbon;
the auxiliary material B is prepared from the following components in parts by weight: 18 parts of diluent, 9 parts of cross-linking agent, 20 parts of surfactant, 21 parts of plasticizer, 9 parts of modifier and 23 parts of lubricant.
Furthermore, the particle size specification of the calcium carbonate powder is 700 meshes, and the glass fiber and the seaweed carbon are both powdery substances.
Further, the diluent is acetone and styrene, and the cross-linking agent is diethylamine.
Furthermore, the surfactant is sodium dodecyl benzene sulfonate, and the plasticizer is diphenyl isopropyl phenyl phosphate.
Further, the preparation method of the transparent application patch for the indwelling needle comprises the following steps:
s1, preparation: preparing an electronic scale, a reaction kettle I, a reaction kettle II, a film stretching machine, a blow molding machine, a dispersion machine and a plurality of material storage cylinders;
s2, weighing the main materials and the auxiliary materials: weighing the weight of each component in the main material A and the auxiliary material B by using an electronic scale, and correspondingly placing the components of the main material A in one storage cylinder and the components of the auxiliary material B in the other storage cylinder for later use after weighing;
s3, preparing a main material A: starting a reaction kettle I, adding all components of the main material A into the reaction kettle I, adjusting the rotating speed of the reaction kettle I to be 500r/min, the pressure to be 0.6MPa and the temperature to be 27 ℃ until the components of the main material A are uniformly mixed, and discharging the main material A from the reaction kettle I for later use;
s4, preparing an auxiliary material B: starting the reaction kettle II, adding all the components of the auxiliary material B into the reaction kettle II, and adjusting the rotating speed of the reaction kettle II to be 300r/min, the pressure to be 0.8MPa and the temperature to be 50 ℃ until the components of the auxiliary material B are uniformly mixed;
s5, preparing a mixture of the main material A and the auxiliary material B: adding the main material A prepared in the step S3 into a reaction kettle II, starting the reaction kettle II again, adjusting the rotating speed of the reaction kettle II to be 1000r/min, the pressure to be 1.5MPa and the temperature to be 75 ℃ until the main material A and the auxiliary material B are completely mixed, discharging the main material A from the reaction kettle II, and standing and cooling the main material A and the auxiliary material B for later use to obtain a mixed material;
s6, dispersing the mixture: putting the mixture prepared in the step S5 into a dispersion machine, and taking out after the mixture is fully dispersed;
s7, stretching the mixture: adding the mixture dispersed in the step S6 into a stretcher, and stretching the mixture;
s8, blow molding: putting the mixture stretched in the step S7 into a blow molding machine, and molding the mixture to obtain a transparent adhesive film;
s9, cutting and packaging: the transparent application film obtained in step S8 is subjected to a cutting process in accordance with the medical specification, and packaged.
Example 2
The invention provides a technical scheme that: a transparent plaster for an indwelling needle comprises a main material A and an auxiliary material B,
the main material A is prepared from the following components in parts by weight: 31 parts of deionized water, 85 parts of polyethylene resin, 32 parts of calcium carbonate powder, 17 parts of nano titanium dioxide, 8 parts of glass fiber and 13 parts of seaweed carbon;
the auxiliary material B is prepared from the following components in parts by weight: 11 parts of diluent, 5 parts of cross-linking agent, 14 parts of surfactant, 16 parts of plasticizer, 5 parts of modifier and 17 parts of lubricant.
Furthermore, the particle size specification of the calcium carbonate powder is 900 meshes, and both the glass fiber and the seaweed carbon are powdery substances.
Furthermore, the diluent is toluene and xylene, and the cross-linking agent is 2-isopropyl imidazole.
Further, the surfactant is fatty glyceride, and the plasticizer is diphenyl isopropyl phenyl phosphate.
Further, the preparation method of the transparent application patch for the indwelling needle comprises the following steps:
s1, preparation: preparing an electronic scale, a reaction kettle I, a reaction kettle II, a film stretching machine, a blow molding machine, a dispersion machine and a plurality of material storage cylinders;
s2, weighing the main materials and the auxiliary materials: weighing the weight of each component in the main material A and the auxiliary material B by using an electronic scale, and correspondingly placing the components of the main material A in one storage cylinder and the components of the auxiliary material B in the other storage cylinder for later use after weighing;
s3, preparing a main material A: starting a reaction kettle I, adding all components of the main material A into the reaction kettle I, adjusting the rotating speed of the reaction kettle I to be 300r/min, the pressure intensity to be 0.3MPa and the temperature to be 23 ℃ until the components of the main material A are uniformly mixed, and discharging the main material A from the reaction kettle I for later use;
s4, preparing an auxiliary material B: starting the reaction kettle II, adding all the components of the auxiliary material B into the reaction kettle II, and adjusting the rotating speed of the reaction kettle II to be 200r/min, the pressure to be 0.5MPa and the temperature to be 45 ℃ until the components of the auxiliary material B are uniformly mixed;
s5, preparing a mixture of the main material A and the auxiliary material B: adding the main material A prepared in the step S3 into a reaction kettle II, starting the reaction kettle II again, adjusting the rotating speed of the reaction kettle II to be 800r/min, the pressure to be 1.2MPa and the temperature to be 65 ℃ until the main material A and the auxiliary material B are completely mixed, discharging the main material A from the reaction kettle II, and standing and cooling the main material A and the auxiliary material B for later use to obtain a mixed material;
s6, dispersing the mixture: putting the mixture prepared in the step S5 into a dispersion machine, and taking out after the mixture is fully dispersed;
s7, stretching the mixture: adding the mixture dispersed in the step S6 into a stretcher, and stretching the mixture;
s8, blow molding: putting the mixture stretched in the step S7 into a blow molding machine, and molding the mixture to obtain a transparent adhesive film;
s9, cutting and packaging: the transparent application film obtained in step S8 is subjected to a cutting process in accordance with the medical specification, and packaged.
Example 3
The invention provides a technical scheme that: a transparent plaster for an indwelling needle comprises a main material A and an auxiliary material B,
the main material A is prepared from the following components in parts by weight: 40 parts of deionized water, 90 parts of polyethylene resin, 35 parts of calcium carbonate powder, 25 parts of nano titanium dioxide, 13 parts of glass fiber and 16 parts of seaweed carbon;
the auxiliary material B is prepared from the following components in parts by weight: 14 parts of diluent, 8 parts of cross-linking agent, 18 parts of surfactant, 18 parts of plasticizer, 8 parts of modifier and 21 parts of lubricant.
Furthermore, the particle size specification of the calcium carbonate powder is 800 meshes, and both the glass fiber and the seaweed carbon are powdery substances.
Furthermore, the diluent is xylene and styrene, and the crosslinking agent is dimethylaminopropylamine.
Further, the surfactant is lecithin, and the plasticizer is tributyl phosphate.
Further, the preparation method of the transparent application patch for the indwelling needle comprises the following steps:
s1, preparation: preparing an electronic scale, a reaction kettle I, a reaction kettle II, a film stretching machine, a blow molding machine, a dispersion machine and a plurality of material storage cylinders;
s2, weighing the main materials and the auxiliary materials: weighing the weight of each component in the main material A and the auxiliary material B by using an electronic scale, and correspondingly placing the components of the main material A in one storage cylinder and the components of the auxiliary material B in the other storage cylinder for later use after weighing;
s3, preparing a main material A: starting a reaction kettle I, adding all components of the main material A into the reaction kettle I, adjusting the rotating speed of the reaction kettle I to be 400r/min, the pressure intensity to be 0.5MPa and the temperature to be 26 ℃ until the components of the main material A are uniformly mixed, and discharging the main material A from the reaction kettle I for later use;
s4, preparing an auxiliary material B: starting the reaction kettle II, adding all the components of the auxiliary material B into the reaction kettle II, and adjusting the rotating speed of the reaction kettle II to be 250r/min, the pressure to be 0.6MPa and the temperature to be 49 ℃ until the components of the auxiliary material B are uniformly mixed;
s5, preparing a mixture of the main material A and the auxiliary material B: adding the main material A prepared in the step S3 into a reaction kettle II, starting the reaction kettle II again, adjusting the rotating speed of the reaction kettle II to be 900r/min, the pressure intensity to be 1.3MPa and the temperature to be 70 ℃ until the main material A and the auxiliary material B are completely mixed, discharging the main material A from the reaction kettle II, and standing and cooling the main material A and the auxiliary material B for later use to obtain a mixed material;
s6, dispersing the mixture: putting the mixture prepared in the step S5 into a dispersion machine, and taking out after the mixture is fully dispersed;
s7, stretching the mixture: adding the mixture dispersed in the step S6 into a stretcher, and stretching the mixture;
s8, blow molding: putting the mixture stretched in the step S7 into a blow molding machine, and molding the mixture to obtain a transparent adhesive film;
s9, cutting and packaging: the transparent application film obtained in step S8 is subjected to a cutting process in accordance with the medical specification, and packaged.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. A transparent plaster for an indwelling needle comprises a main material A and an auxiliary material B, and is characterized in that:
the main material A comprises deionized water, polyethylene resin, calcium carbonate powder, nano titanium dioxide, glass fiber and seaweed carbon, and is prepared from the following components in parts by weight: 31-45 parts of deionized water, 85-100 parts of polyethylene resin, 32-37 parts of calcium carbonate powder, 17-26 parts of nano titanium dioxide, 8-15 parts of glass fiber and 13-18 parts of seaweed carbon;
the auxiliary material B comprises a diluent, a cross-linking agent, a surfactant, a plasticizer, a modifier and a lubricant, and is prepared from the following components in parts by weight: 11-18 parts of diluent, 5-9 parts of cross-linking agent, 14-20 parts of surfactant, 16-21 parts of plasticizer, 5-9 parts of modifier and 17-23 parts of lubricant.
2. The transparent dressing for an indwelling needle according to claim 1, wherein: the main material A is prepared from the following components in parts by weight: 45 parts of deionized water, 100 parts of polyethylene resin, 37 parts of calcium carbonate powder, 26 parts of nano titanium dioxide, 15 parts of glass fiber and 18 parts of seaweed carbon;
the auxiliary material B is prepared from the following components in parts by weight: 18 parts of diluent, 9 parts of cross-linking agent, 20 parts of surfactant, 21 parts of plasticizer, 9 parts of modifier and 23 parts of lubricant.
3. The transparent dressing for an indwelling needle according to claim 1, wherein: the main material A is prepared from the following components in parts by weight: 31 parts of deionized water, 85 parts of polyethylene resin, 32 parts of calcium carbonate powder, 17 parts of nano titanium dioxide, 8 parts of glass fiber and 13 parts of seaweed carbon;
the auxiliary material B is prepared from the following components in parts by weight: 11 parts of diluent, 5 parts of cross-linking agent, 14 parts of surfactant, 16 parts of plasticizer, 5 parts of modifier and 17 parts of lubricant.
4. The transparent dressing for an indwelling needle according to claim 1, wherein: the main material A is prepared from the following components in parts by weight: 40 parts of deionized water, 90 parts of polyethylene resin, 35 parts of calcium carbonate powder, 25 parts of nano titanium dioxide, 13 parts of glass fiber and 16 parts of seaweed carbon;
the auxiliary material B is prepared from the following components in parts by weight: 14 parts of diluent, 8 parts of cross-linking agent, 18 parts of surfactant, 18 parts of plasticizer, 8 parts of modifier and 21 parts of lubricant.
5. The transparent dressing for an indwelling needle according to claim 1, wherein: the particle size specification of the calcium carbonate powder is 700-900 meshes, and the glass fiber and the seaweed carbon are both powdery substances.
6. The transparent dressing for an indwelling needle according to claim 1, wherein: the diluent is formed by mixing one or more of acetone, toluene, xylene and styrene, and the cross-linking agent is formed by mixing one or more of diethylamine, 2-isopropylimidazole and dimethylaminopropylamine.
7. The transparent dressing for an indwelling needle according to claim 1, wherein: the surface active agent is formed by mixing one or more of sodium dodecyl benzene sulfonate, fatty glyceride and lecithin, and the plasticizer is formed by mixing one or more of diphenyl isopropyl phenyl phosphate, trichloroethyl phosphate and tributyl phosphate.
8. The transparent dressing for an indwelling needle according to any one of claims 1 to 7, wherein: the preparation method comprises the following steps:
s1, preparation: preparing an electronic scale, a reaction kettle I, a reaction kettle II, a film stretching machine, a blow molding machine, a dispersion machine and a plurality of material storage cylinders;
s2, weighing the main materials and the auxiliary materials: weighing the weight of each component in the main material A and the auxiliary material B by using an electronic scale, and correspondingly placing the components of the main material A in one storage cylinder and the components of the auxiliary material B in the other storage cylinder for later use after weighing;
s3, preparing a main material A: starting the reaction kettle I, adding all the components of the main material A into the reaction kettle I, adjusting the rotating speed of the reaction kettle I to be 300-0.6 MPa, the pressure intensity to be 0.3-0.6MPa and the temperature to be 23-27 ℃ until the components of the main material A are uniformly mixed, and discharging the main material A from the reaction kettle I for later use;
s4, preparing an auxiliary material B: starting the reaction kettle II, adding all the components of the auxiliary material B into the reaction kettle II, and adjusting the rotating speed of the reaction kettle II to be 200-0.8 MPa, the pressure intensity to be 0.5-0.8MPa and the temperature to be 45-50 ℃ until the components of the auxiliary material B are uniformly mixed;
s5, preparing a mixture of the main material A and the auxiliary material B: adding the main material A prepared in the step S3 into a reaction kettle II, starting the reaction kettle II again, adjusting the rotating speed of the reaction kettle II to be 800-1000r/min, the pressure to be 1.2-1.5MPa and the temperature to be 65-75 ℃ until the main material A and the auxiliary material B are completely mixed, discharging the mixture from the reaction kettle II, standing and cooling the mixture for later use to obtain a mixed material;
s6, dispersing the mixture: putting the mixture prepared in the step S5 into a dispersion machine, and taking out after the mixture is fully dispersed;
s7, stretching the mixture: adding the mixture dispersed in the step S6 into a stretcher, and stretching the mixture;
s8, blow molding: putting the mixture stretched in the step S7 into a blow molding machine, and molding the mixture to obtain a transparent adhesive film;
s9, cutting and packaging: the transparent application film obtained in step S8 is subjected to a cutting process in accordance with the medical specification, and packaged.
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| CN201911300931.2A CN111035790A (en) | 2019-12-17 | 2019-12-17 | Transparent application for indwelling needle and preparation method thereof |
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Application publication date: 20200421 |