CN110917937A - Purification device for ursodeoxycholic acid crude product - Google Patents
Purification device for ursodeoxycholic acid crude product Download PDFInfo
- Publication number
- CN110917937A CN110917937A CN201911145703.2A CN201911145703A CN110917937A CN 110917937 A CN110917937 A CN 110917937A CN 201911145703 A CN201911145703 A CN 201911145703A CN 110917937 A CN110917937 A CN 110917937A
- Authority
- CN
- China
- Prior art keywords
- stirring
- ursodeoxycholic acid
- cylinder
- crude product
- communicated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- RUDATBOHQWOJDD-UZVSRGJWSA-N Ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 title claims abstract description 40
- 229960001661 Ursodiol Drugs 0.000 title claims abstract description 40
- 229940115889 ursodeoxycholic acid Drugs 0.000 title claims abstract description 40
- 239000012043 crude product Substances 0.000 title claims abstract description 27
- 238000000746 purification Methods 0.000 title claims abstract description 20
- 238000003756 stirring Methods 0.000 claims abstract description 49
- 238000000926 separation method Methods 0.000 claims abstract description 34
- 239000012535 impurity Substances 0.000 claims abstract description 14
- 229920002456 HOTAIR Polymers 0.000 claims abstract description 9
- 238000001914 filtration Methods 0.000 claims description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 238000007599 discharging Methods 0.000 claims description 10
- 230000001681 protective Effects 0.000 claims description 10
- 230000017525 heat dissipation Effects 0.000 claims description 8
- 229910052751 metal Inorganic materials 0.000 claims description 7
- 239000002184 metal Substances 0.000 claims description 7
- 239000000428 dust Substances 0.000 claims description 6
- 239000011343 solid material Substances 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 5
- 229920000742 Cotton Polymers 0.000 claims description 4
- 238000001704 evaporation Methods 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 3
- 229920001821 Foam rubber Polymers 0.000 claims description 2
- 238000003466 welding Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 5
- HVYWMOMLDIMFJA-DPAQBDIFSA-N (3β)-Cholest-5-en-3-ol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 210000000941 Bile Anatomy 0.000 description 2
- 229940107161 Cholesterol Drugs 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 229960000583 Acetic Acid Drugs 0.000 description 1
- 208000001130 Gallstone Diseases 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 230000031200 bile acid secretion Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 150000001840 cholesterol esters Chemical class 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000006011 modification reaction Methods 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
- B01F27/90—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with paddles or arms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D1/00—Evaporating
- B01D1/14—Evaporating with heated gases or vapours or liquids in contact with the liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Other filters with filtering elements stationary during filtration, e.g. pressure or suction filters, or filtering elements therefor
- B01D29/01—Other filters with filtering elements stationary during filtration, e.g. pressure or suction filters, or filtering elements therefor with flat filtering elements
- B01D29/03—Other filters with filtering elements stationary during filtration, e.g. pressure or suction filters, or filtering elements therefor with flat filtering elements self-supporting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D33/00—Filters with filtering elements which move during the filtering operation
- B01D33/01—Filters with filtering elements which move during the filtering operation with translationally moving filtering elements, e.g. pistons
- B01D33/03—Filters with filtering elements which move during the filtering operation with translationally moving filtering elements, e.g. pistons with vibrating filter elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D36/00—Filter circuits or combinations of filters with other separating devices
- B01D36/02—Combinations of filters of different kinds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F21/00—Dissolving
- B01F21/10—Dissolving using driven stirrers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Abstract
The invention discloses a purification device for ursodeoxycholic acid crude products, which comprises a base, wherein a stirring mechanism is fixed above the base through a first support column, the stirring mechanism comprises a stirring cylinder, the bottom of the stirring cylinder is communicated with a separation mechanism through a first discharge pipe, the separation mechanism comprises a separation box, the side wall of the separation box is communicated with a filter mechanism through a second discharge pipe, the filter mechanism comprises a filter cylinder, a vibrating screen is arranged between the inner walls of the filter cylinder, a hot air blower is arranged on the outer wall of the filter cylinder, and a collection box is arranged above the base Good effect, and the removed impurities can be recycled.
Description
Technical Field
The invention belongs to the technical field of ursodeoxycholic acid purification, and particularly relates to a purification device for a crude product of ursodeoxycholic acid. Meanwhile, the invention also relates to a purification method of the ursodeoxycholic acid crude product.
Background
Ursodeoxycholic acid, an organic compound, is in the form of white crystalline powder, odorless, bitter. The product is hardly dissolved in water, is easily dissolved in ethanol, and is insoluble in chloroform; it is easily soluble in glacial acetic acid, and is soluble in sodium hydroxide solution. The medicine is used for increasing bile acid secretion, changing bile components, reducing cholesterol and cholesterol ester in bile and being beneficial to gradually dissolving cholesterol in gallstone.
The crude product obtained in the ursodeoxycholic acid production process contains a large amount of impurities, and can be put into use only after purification. Because ursodeoxycholic acid is almost insoluble in water and is difficult to purify in a dissolving and evaporating mode, a simple device capable of effectively purifying crude ursodeoxycholic acid is not available in the market at present, the purification effect is achieved mostly through reaction of various compounds, and foreign substances are mixed in the ursodeoxycholic acid, so that the basic purpose is violated.
Disclosure of Invention
The invention aims to provide a purification device for ursodeoxycholic acid crude products, which aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a purification device for ursodeoxycholic acid crude products comprises a base, wherein a stirring mechanism is fixed above the base through a first support column;
the stirring mechanism comprises a stirring drum, a protective cover is welded at the top of the stirring drum, a motor is installed in the protective cover, the bottom end of an output shaft of the motor penetrates through the top of the stirring drum and is connected with a stirring shaft through a coupler, stirring blades are arranged on the stirring shaft, the top of the stirring drum is communicated with a feeding pipe and a water inlet pipe, and the bottom of the stirring drum is communicated with the separating mechanism through a first discharging pipe;
the separation mechanism comprises a separation box, the top of the separation box is communicated with the outlet end of the first discharge pipe, the bottom of the separation box is connected with the upper surface of the base through a second support column, a metal filter screen is embedded between the inner walls of the separation box, and the side wall of the separation box is communicated with the filtering mechanism through a second discharge pipe;
the filter mechanism comprises a filter cartridge, the top of the side wall of the filter cartridge is communicated with the outlet end of the second discharge pipe, the bottom of the filter cartridge is connected with the upper surface of the base through a third support column, a vibrating screen is arranged between the inner walls of the filter cartridge, an air heater is arranged on the outer wall of the filter cartridge, the air outlet of the air heater is communicated with the inside of the filter cartridge through an air outlet pipe, and the bottom of the filter cartridge is communicated with a third discharge pipe;
and a collecting box is placed above the base and is positioned under the third discharge pipe.
Preferably, the protective cover is provided with heat dissipation holes, and filter cotton nets are embedded in the heat dissipation holes.
Preferably, the bottom of the separator is communicated with a drain pipe, and the first discharge pipe and the drain pipe are respectively provided with a first valve and a second valve.
Preferably, the top of the filter cylinder is provided with an exhaust port, and a dust filter screen is embedded in the exhaust port.
Preferably, the bottom of the mixing drum, the bottom of the separation box and the bottom of the filtering drum are all arranged in an inverted cone shape.
Preferably, the base upper surface welding has the limiting plate, the limiting plate is located collecting box one side, it has the foam-rubber cushion to glue near collecting box one side on the limiting plate.
Preferably, the limiting plate and the collecting box are embedded with magnetic blocks correspondingly.
The invention also provides a purification method of the ursodeoxycholic acid crude product, which comprises the following steps:
s1, closing the first valve, pouring the ursodeoxycholic acid crude product and the mixed water into a stirring cylinder from a feeding pipe and a water inlet pipe respectively, starting a motor, and stirring the ursodeoxycholic acid crude product by a stirring blade to dissolve water-soluble impurities in the ursodeoxycholic acid crude product;
s2, starting the air heater in advance, opening the first valve, enabling the mixture obtained in the first step to enter the separation box from the first discharge pipe, enabling the solution to pass through the metal filter screen and be accumulated at the bottom of the separation box, and enabling undissolved solid materials to enter the filter cylinder from the second discharge pipe;
s3, starting the vibrating screen, evaporating residual moisture on the surface of the solid material by the hot air blower, discharging water vapor from the exhaust port, intercepting large water-insoluble impurities above the vibrating screen, and making ursodeoxycholic acid crystal powder pass through the vibrating screen and fall into the collection box from the third discharge pipe.
The purification device for the ursodeoxycholic acid crude product provided by the invention has the beneficial effects that:
the device provided by the invention can be used for sequentially removing water-soluble impurities, mixed aqueous solution and water-insoluble impurities mixed in the crude ursodeoxycholic acid product by arranging the stirring cylinder, the separation box and the filtering cylinder, so that the purification function of the crude ursodeoxycholic acid product is realized, meanwhile, the device is simple in structure, high in purification efficiency and good in effect, and the removed impurities can be recycled.
Drawings
FIG. 1 is a front cross-sectional structural schematic view of the present invention;
FIG. 2 is a schematic structural diagram of a stirring mechanism according to the present invention;
FIG. 3 is a schematic view of the separating mechanism of the present invention;
FIG. 4 is a schematic view of the filter mechanism of the present invention;
FIG. 5 is a side cross-sectional structural schematic view of the collection tank of the present invention.
In the figure: 1. a base; 2. a first support column; 3. a stirring mechanism; 4. a mixing drum; 5. a protective cover; 6. a motor; 7. a stirring shaft; 8. a stirring blade; 9. a feed pipe; 10. a water inlet pipe; 11. a first discharge pipe; 12. a separating mechanism; 13. a separation tank; 14. a metal screen; 15. a second discharge pipe; 16. a filtering mechanism; 17. a filter cartridge; 18. vibrating a screen; 19. a hot air blower; 20. an air outlet pipe; 21. a third discharge pipe; 22. a collection box; 23. a second support column; 24. a third support column; 25. heat dissipation holes; 26. filtering the cotton net; 27. a drain pipe; 28. a first valve; 29. a second valve; 30. an exhaust port; 31. a dust filter screen; 32. a limiting plate; 33. a sponge cushion; 34. a magnetic block.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The invention provides a purification device for ursodeoxycholic acid crude products as shown in figures 1-5, which comprises a base 1, wherein a stirring mechanism 3 is fixed above the base 1 through a first supporting column 2;
the stirring mechanism 3 comprises a stirring cylinder 4, a protective cover 5 is welded at the top of the stirring cylinder 4, a motor 6 is installed in the protective cover 5, in order to facilitate heat dissipation of the motor 6, heat dissipation holes 25 are formed in the protective cover 5, a filter cotton net 26 is embedded in the heat dissipation holes 25 and used for preventing dust from entering, the bottom end of an output shaft of the motor 6 penetrates through the top of the stirring cylinder 4 and is connected with a stirring shaft 7 through a coupler, stirring blades 8 are arranged on the stirring shaft 7, the top of the stirring cylinder 4 is communicated with a feeding pipe 9 and a water inlet pipe 10, and the bottom of the stirring cylinder 4 is communicated with a separating mechanism;
the separation mechanism 12 comprises a separation box 13, the top of the separation box 13 is communicated with the outlet end of the first discharge pipe 11, the bottom of the separation box 13 is connected with the upper surface of the base 1 through a second support column 23, a metal filter screen 14 is embedded between the inner walls of the separation box 13, the side wall of the separation box 13 is communicated with a filtering mechanism 16 through a second discharge pipe 15, the bottom of the separation box 13 is communicated with a drain pipe 27, the drain pipe 27 can be communicated with an external recovery box, and the first discharge pipe 11 and the drain pipe 27 are respectively provided with a first valve 28 and a second valve 29;
the filtering mechanism 16 comprises a filtering cylinder 17, the top of the side wall of the filtering cylinder 17 is communicated with the outlet end of the second discharging pipe 15, the bottom of the filtering cylinder 17 is connected with the upper surface of the base 1 through a third supporting column 24, a vibrating screen 18 is installed between the inner walls of the filtering cylinder 17, the aperture of the vibrating screen 18 is slightly larger than the diameter of ursodeoxycholic acid crystal powder, an air heater 19 is installed on the outer wall of the filtering cylinder 17, the air outlet of the air heater 19 is communicated with the inside of the filtering cylinder 17 through an air outlet pipe 20, in order to accelerate the discharge of water vapor, an air outlet 30 is formed in the top of the filtering cylinder 17, a dust filtering net 31 is embedded in the air outlet 30 and can prevent dust;
the collecting box 22 is placed above the base 1, the collecting box 22 is located under the third discharging pipe 21, in order to position the collecting box 22 conveniently, the limiting plate 32 is welded on the upper surface of the base 1, the limiting plate 32 is located on one side of the collecting box 22, one side, close to the collecting box 22, of the limiting plate 32 is connected with the sponge pad 33 in a gluing mode, the limiting plate 32 is in flexible contact with the side wall of the collecting box 22, and the magnetic blocks 34 are correspondingly embedded in the limiting plate 32 and the side wall of the collecting box 22 to play a role in assisting in fixing the collecting box 22;
the bottom of the mixing drum 4, the bottom of the separating box 13 and the bottom of the filter cartridge 17 are all inverted conical, so that the mixing drum is convenient to discharge.
The invention also provides a purification method of the ursodeoxycholic acid crude product, which comprises the following steps:
s1, closing the first valve 28, pouring the ursodeoxycholic acid crude product and the mixed water into the stirring cylinder 4 from the feeding pipe 9 and the water inlet pipe 10 respectively, starting the motor 6, and stirring the ursodeoxycholic acid crude product by the stirring blade 8 to dissolve water-soluble impurities;
s2, starting the hot air blower 19 in advance, opening the first valve 28, enabling the mixture obtained in the first step to enter the separation box 13 from the first discharge pipe 11, enabling the solution to pass through the metal filter screen 14 and be accumulated at the bottom of the separation box 13, and enabling undissolved solid materials to enter the filter cylinder 17 from the second discharge pipe 15;
s3, starting the vibrating screen 18, evaporating residual moisture on the surface of the solid material by the hot air blower 19, discharging water vapor from the exhaust port 30, intercepting large water-insoluble impurities above the vibrating screen 18, and making ursodeoxycholic acid crystal powder fall into the collection box 22 from the third discharge pipe 21 through the vibrating screen 18.
Therefore, the invention can remove water-soluble impurities, mixed aqueous solution and water-insoluble impurities mixed in the crude ursodeoxycholic acid in sequence by arranging the stirring cylinder 4, the separation box 13 and the filter cylinder 17, realizes the purification function of the crude ursodeoxycholic acid, and has the advantages of simple structure, high purification efficiency and good purification effect, and the removed impurities can be recycled.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (8)
1. The utility model provides a ursodeoxycholic acid is purification device for crude product, includes base (1), its characterized in that: a stirring mechanism (3) is fixed above the base (1) through a first supporting column (2);
the stirring mechanism (3) comprises a stirring cylinder (4), a protective cover (5) is welded at the top of the stirring cylinder (4), a motor (6) is installed in the protective cover (5), the bottom end of an output shaft of the motor (6) penetrates through the top of the stirring cylinder (4) and is connected with a stirring shaft (7) through a coupler, stirring blades (8) are arranged on the stirring shaft (7), the top of the stirring cylinder (4) is communicated with a feeding pipe (9) and a water inlet pipe (10), and the bottom of the stirring cylinder (4) is communicated with a separating mechanism (12) through a first discharging pipe (11);
the separation mechanism (12) comprises a separation box (13), the top of the separation box (13) is communicated with the outlet end of the first discharge pipe (11), the bottom of the separation box (13) is connected with the upper surface of the base (1) through a second support column (23), a metal filter screen (14) is embedded between the inner walls of the separation box (13), and the side wall of the separation box (13) is communicated with the filtering mechanism (16) through a second discharge pipe (15);
the filtering mechanism (16) comprises a filtering cylinder (17), the top of the side wall of the filtering cylinder (17) is communicated with the outlet end of the second discharging pipe (15), the bottom of the filtering cylinder (17) is connected with the upper surface of the base (1) through a third supporting column (24), a vibrating screen (18) is installed between the inner walls of the filtering cylinder (17), a hot air blower (19) is installed on the outer wall of the filtering cylinder (17), the air outlet of the hot air blower (19) is communicated with the inside of the filtering cylinder (17) through an air outlet pipe (20), and the bottom of the filtering cylinder (17) is communicated with a third discharging pipe (21);
a collecting box (22) is arranged above the base (1), and the collecting box (22) is positioned under the third discharging pipe (21).
2. The device for purifying ursodeoxycholic acid crude product according to claim 1, wherein: the protective cover (5) is provided with heat dissipation holes (25), and filter cotton nets (26) are embedded into the heat dissipation holes (25).
3. The device for purifying ursodeoxycholic acid crude product according to claim 1, wherein: the bottom of the separation box (13) is communicated with a drain pipe (27), and a first valve (28) and a second valve (29) are respectively arranged on the first discharge pipe (11) and the drain pipe (27).
4. The device for purifying ursodeoxycholic acid crude product according to claim 1, wherein: an exhaust port (30) is formed in the top of the filter cartridge (17), and a dust filtering net (31) is embedded in the exhaust port (30).
5. The device for purifying ursodeoxycholic acid crude product according to claim 1, wherein: the bottom parts of the mixing drum (4), the separating box (13) and the filter cartridge (17) are all arranged in an inverted cone shape.
6. The device for purifying ursodeoxycholic acid crude product according to claim 1, wherein: the utility model discloses a base (1) upper surface welding has limiting plate (32), limiting plate (32) are located collecting box (22) one side, limiting plate (32) are gone up and are close to collecting box (22) one side and splice there is foam-rubber cushion (33).
7. The device for purifying ursodeoxycholic acid crude product according to claim 6, wherein: and magnetic blocks (34) are correspondingly embedded in the limiting plate (32) and the side wall of the collecting box (22).
8. The method for purifying ursodeoxycholic acid crude product according to claim 1, wherein: the method specifically comprises the following steps:
s1, closing a first valve (28), pouring the ursodeoxycholic acid crude product and the mixed water into a stirring cylinder (4) from a feeding pipe (9) and a water inlet pipe (10) respectively, starting a motor (6), and stirring the ursodeoxycholic acid crude product by a stirring blade (8) to dissolve water-soluble impurities;
s2, starting the hot air blower (19) in advance, opening the first valve (28), enabling the mixture obtained in the first step to enter the separation box (13) from the first discharge pipe (11), enabling the solution to pass through the metal filter screen (14) and be accumulated at the bottom of the separation box (13), and enabling the undissolved solid materials to enter the filter cylinder (17) from the second discharge pipe (15);
s3, starting the vibrating screen (18), evaporating residual moisture on the surface of the solid material by the hot air blower (19), discharging water vapor from the exhaust port (30), intercepting large water-insoluble impurities above the vibrating screen (18), and making ursodeoxycholic acid crystal powder pass through the vibrating screen (18) and fall into the collection box (22) from the third discharge pipe (21).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911145703.2A CN110917937A (en) | 2019-11-21 | 2019-11-21 | Purification device for ursodeoxycholic acid crude product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911145703.2A CN110917937A (en) | 2019-11-21 | 2019-11-21 | Purification device for ursodeoxycholic acid crude product |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110917937A true CN110917937A (en) | 2020-03-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911145703.2A Pending CN110917937A (en) | 2019-11-21 | 2019-11-21 | Purification device for ursodeoxycholic acid crude product |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110917937A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002306902A (en) * | 2001-04-13 | 2002-10-22 | Mitsubishi Chemicals Corp | Method for crystallizing and/or refining organic compound |
| CN207769340U (en) * | 2017-12-18 | 2018-08-28 | 吴世亮 | A kind of efficient chemical industry filter device |
| CN208161085U (en) * | 2018-04-09 | 2018-11-30 | 吴泽恩 | A kind of chemical reagent equipment for purifying |
| CN209349142U (en) * | 2018-12-11 | 2019-09-06 | 江苏德鑫新材料科技有限公司 | A kind of quartz sand purifying feeds online rinses sorting unit |
| CN110280573A (en) * | 2019-07-31 | 2019-09-27 | 武汉轻工大学 | A kind of industrial waste residue disposal device |
-
2019
- 2019-11-21 CN CN201911145703.2A patent/CN110917937A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002306902A (en) * | 2001-04-13 | 2002-10-22 | Mitsubishi Chemicals Corp | Method for crystallizing and/or refining organic compound |
| CN207769340U (en) * | 2017-12-18 | 2018-08-28 | 吴世亮 | A kind of efficient chemical industry filter device |
| CN208161085U (en) * | 2018-04-09 | 2018-11-30 | 吴泽恩 | A kind of chemical reagent equipment for purifying |
| CN209349142U (en) * | 2018-12-11 | 2019-09-06 | 江苏德鑫新材料科技有限公司 | A kind of quartz sand purifying feeds online rinses sorting unit |
| CN110280573A (en) * | 2019-07-31 | 2019-09-27 | 武汉轻工大学 | A kind of industrial waste residue disposal device |
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Application publication date: 20200327 |