CN110865194A - Milk small molecule bioactive peptide detection device - Google Patents
Milk small molecule bioactive peptide detection device Download PDFInfo
- Publication number
- CN110865194A CN110865194A CN201911196250.6A CN201911196250A CN110865194A CN 110865194 A CN110865194 A CN 110865194A CN 201911196250 A CN201911196250 A CN 201911196250A CN 110865194 A CN110865194 A CN 110865194A
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- China
- Prior art keywords
- equipment
- storage box
- bioactive peptide
- equipment storage
- experimental
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
Abstract
The invention relates to the technical field of protein detection, in particular to a milk small-molecule bioactive peptide detection device which comprises a machine shell and a fast atom bombardment ionization protein mass spectrometer, wherein a vertical partition plate is arranged in the machine shell and divides the interior of the machine shell into an equipment bin and an operation bin, the fast atom bombardment ionization protein mass spectrometer for detecting small-molecule bioactive peptides is installed in the equipment bin, an object placing plate is transversely arranged in the operation bin, and an equipment storage box in which experimental equipment is arranged is extended out so as to facilitate taking and using of the experimental equipment; the step of recording the experimenter through the camera, through reading the content in the memory, can make things convenient for whether the experiment operation to the experimenter is normal, when the conclusion of the questioning experiment of someone, can transfer the video recording and pursue the responsibility.
Description
Technical Field
The invention relates to the technical field of protein detection, in particular to a milk small-molecule bioactive peptide detection device.
Background
The milk small molecule bioactive peptide is an important index for detecting nutrient components in milk, and is generally detected by an automatic Edman degradation method or a DNA translation method, but the two methods are often not accurate enough when detecting the small molecule bioactive peptide, and the detection of the small molecule bioactive peptide basically tends to be detected by a mass spectrometer along with the development of the mass spectrometer.
Fast atom bombardment mass spectrometers are a soft ionization technique for mass spectrometers. Hydrogen ions are generated by the discharge of a hydrogen ion gun, the high-energy hydrogen ions pass through a charge exchange chamber charged with hydrogen of about I3.3322Pa (10 torr), and are subjected to resonance charge exchange to obtain high-energy atmosphere H sub-flow, and the hydrogen atom flow is hit on a stagnation matrix (generally glycerol) dissolved with a sample. Ions of a sample to be analyzed are sputtered from a tomb body J-through the ionization process called fast atom bombardment, the limitation that the sample must be heated and gasified in the traditional mass spectrum can be overcome, and the method has the characteristics of small using amount, convenience and quickness in the sequencing process and is suitable for detecting the milk micromolecule bioactive peptide.
The existing fast atom bombardment mass spectrometer is an independent instrument, and when the fast atom bombardment mass spectrometer is used, an experimental instrument needing to be used in a matched mode is not easy to place, and the experimental operation of experimental personnel cannot be traced, so that the fast atom bombardment mass spectrometer is inconvenient to use and needs to be improved.
Disclosure of Invention
In order to solve the technical problems, the invention provides a milk small-molecule bioactive peptide detection device.
The technical problem to be solved by the invention is realized by adopting the following technical scheme:
a milk small molecule biological active peptide detection device comprises a shell and a fast atom bombardment ionization protein mass spectrometer, wherein a vertical partition plate is arranged inside the shell, the partition plate divides the interior of the shell into an equipment bin and an operation bin, the equipment bin is internally provided with the fast atom bombardment ionization protein mass spectrometer for detecting the small molecule biological active peptide, the operation bin is internally and transversely provided with an object placing plate, the upper side surface of the object placing plate is provided with a display and a keyboard and mouse assembly which are matched with the fast atom bombardment ionization protein mass spectrometer, the partition plate is provided with a camera, the camera is used for shooting the operation action of an experimenter, the camera is electrically connected with a read-write memory, the memory is used for storing the video shot by the camera, the inner top of the shell is provided with an equipment storage box, and experimental equipment which is matched with the fast atom bombardment protein mass spectrometer is stored in the equipment storage box, the utility model discloses an equipment storage box, including equipment storage box, electric telescopic handle, controller, electric telescopic handle's back lateral wall is fixed mounting has electric telescopic handle on the equipment storage box's the back lateral wall, electric telescopic handle electric connection has the controller, the controller is used for controlling electric telescopic handle's work.
Preferably, be provided with the foam pad on the inner wall of equipment storage box, the inside of foam pad is seted up with experimental facilities appearance assorted recess.
Preferably, the bottom wall of the equipment storage box is provided with a gravity sensor, and the gravity sensor penetrates through the foam pad to be in contact with the experimental equipment and is used for sensing the weight of the experimental equipment.
Preferably, a transparent glass cover is arranged on the front side of the equipment storage box and hinged to the top wall of the equipment storage box.
Preferably, a drawing plate is further arranged below the object placing plate, sliding blocks are fixedly connected to two ends of the drawing plate, and the sliding blocks are slidably connected into strip-shaped sliding grooves formed in the side wall of the machine shell and the partition plate.
Preferably, the upper side surface of the pull plate is provided with a plurality of special-shaped grooves, and the special-shaped grooves are matched with the base of the experimental equipment.
Compared with the prior art, the invention has the beneficial effects that: the invention relates to a milk small molecule bioactive peptide detection device,
1. by arranging the equipment storage box and the electric telescopic rod, when certain experimental equipment is needed according to the experimental steps, the electric telescopic rod is controlled to extend through the controller, so that the equipment storage box with the built-in experimental equipment is extended, the experimental equipment is convenient to take and use, and meanwhile, the extended equipment storage box can remind an experimenter to put the experimental equipment back to the equipment storage box in time; the step of recording the experimenter through the camera, through reading the content in the memory, can make things convenient for whether the experiment operation to the experimenter is normal, when the conclusion of the questioning experiment of someone, can transfer the video recording and pursue the responsibility.
2. Through setting up the gravity inductor, when experimental facilities was taken out, pressure on the gravity inductor was less than predetermined threshold value, and the gravity inductor took place the signal of telecommunication to the controller this moment, and the controller can't drive electric telescopic handle shrink and reset this moment to only when experimental facilities was put back the normal position, equipment was deposited the case and could be reset, avoids experimental facilities to put in disorder and loses, can effectively avoid experimental facilities to put in disorder by the indiscriminate pendulum, leads to experimental facilities to lose.
Drawings
FIG. 1 is a schematic structural view of the present invention;
fig. 2 is a sectional view taken along line a-a of fig. 1.
In the figure: the device comprises a shell 1, a fast atom bombardment ionized protein mass spectrometer 2, a partition plate 3, an object placing plate 4, a display 5, a camera 7, an equipment storage box 8, an electric telescopic rod 9, a foam pad 10, a gravity sensor 11, a transparent glass cover 12 and a drawing plate 6.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-2, the present invention provides a technical solution:
the invention discloses a milk small molecule biological active peptide detection device, which comprises a machine shell 1 and a fast atom bombardment ionized protein mass spectrometer 2, wherein a vertical partition plate 3 is arranged in the machine shell 1, the partition plate 3 divides the interior of the machine shell 1 into an equipment bin and an operation bin, the fast atom bombardment ionized protein mass spectrometer 2 for detecting small molecule biological active peptide is arranged in the equipment bin, an object placing plate 4 is transversely arranged in the operation bin, a display 5 and a keyboard and mouse assembly which are matched with the fast atom bombardment ionized protein mass spectrometer 2 are arranged on the upper side surface of the object placing plate 4, a camera 7 is arranged on the partition plate 3, the camera 7 is used for shooting the operation action of an experimenter, the camera 7 is electrically connected with a read-write memory, the memory is used for storing videos shot by the camera 7, and an equipment storage box 8 is arranged at the inner top of the machine shell 1, the experimental facilities that the fast atom bombardment ionization protein mass spectrograph 2 of cooperation was used together are deposited to equipment 8 internal storage, fixed mounting has electric telescopic handle 9 on the back lateral wall of equipment storage box 8, electric telescopic handle 9 electric connection has the controller, the controller is used for controlling electric telescopic handle 9's work.
When the device works, the display 5 and the keyboard and mouse assembly are used for controlling the fast atom bombardment ionized protein mass spectrometer 2, when experimental equipment needs to be used, according to the experimental steps, when certain experimental equipment is needed, the controller is used for controlling the electric telescopic rod 9 to extend, so that the equipment storage box 8 with the built-in experimental equipment is extended out, the experimental equipment is convenient to take and use, meanwhile, the extended equipment storage box 8 can remind experimenters, and the experimental equipment can be timely put back into the equipment storage box 8; the camera 7 is used for recording the steps of the experimenter, the content in the storage is read, whether the experiment operation of the experimenter is standard or not can be facilitated, and when the conclusion of a person about the questioning experiment is reached, the video recording can be called to pursue.
As an embodiment of the invention, a foam pad 10 is arranged on the inner wall of the equipment storage box 8, a groove matched with the appearance of the experimental equipment is formed inside the foam pad 10, and the foam pad 10 can limit the shaking of the experimental equipment, so that the experimental equipment is protected.
As an embodiment of the present invention, a gravity sensor 11 is installed on the bottom wall of the equipment storage box 8, the gravity sensor 11 penetrates through the foam pad 10 to contact with the experimental equipment, and is used for sensing the weight of the experimental equipment, when the experimental equipment is taken out, the pressure on the gravity sensor 11 is lower than a preset threshold, at this time, the gravity sensor 11 generates an electrical signal to the controller, and at this time, the controller cannot drive the electric telescopic rod 9 to contract and reset, so that the equipment storage box 8 can be reset only when the experimental equipment is put back to the original position, and the experimental equipment is prevented from being randomly put and lost.
As an embodiment of the invention, a transparent glass cover 12 is arranged on the front side of the equipment storage box 8, the transparent glass cover 12 is hinged with the top wall of the equipment storage box 8, and the experimental equipment can be conveniently observed through the transparent glass cover 12.
As an embodiment of the invention, a drawing plate 6 is further arranged below the object placing plate 4, two ends of the drawing plate 6 are fixedly connected with sliding blocks, and the sliding blocks are slidably connected in strip-shaped sliding grooves formed in the side wall of the machine shell 1 and the partition plate 3; can take out pull board 6 during the use, with the experimental report paper tiling on pull board 6, write on pull board 6.
As an implementation mode of the invention, the upper side surface of the pull plate 6 is provided with a plurality of special-shaped grooves, the special-shaped grooves are matched with the bases of the experimental equipment, the experimental equipment can be temporarily placed in the special-shaped grooves, and the stable placement of the experimental equipment is ensured.
While the invention has been described above with reference to an embodiment, various modifications may be made and equivalents may be substituted for elements thereof without departing from the scope of the invention. In particular, the various features of the embodiments disclosed herein may be used in any combination, provided that there is no structural conflict, and the combinations are not exhaustively described in this specification merely for the sake of brevity and conservation of resources. Therefore, it is intended that the invention not be limited to the particular embodiments disclosed, but that the invention will include all embodiments falling within the scope of the appended claims.
Claims (6)
1. A milk small molecule biological activity peptide detection device which is characterized in that: including casing (1) and fast atom bombardment ionized protein mass spectrometer (2), casing (1) inside is provided with vertical baffle (3), and baffle (3) become equipment storehouse and operation storehouse with the inside partition of casing (1), install fast atom bombardment ionized protein mass spectrometer (2) that are used for little molecule bioactive peptide to detect in the equipment storehouse, transversely be provided with in the operation storehouse and put thing board (4), it is provided with fast atom bombardment ionized protein mass spectrometer (2) complex display (5) and keyboard and mouse subassembly to put the side of thing board (4), is provided with camera (7) on baffle (3), camera (7) are used for shooing experimenter's operation action, and camera (7) electric connection has the memory that can read and write, the memory is used for storing the video of camera (7) shooting, the interior top of casing (1) is provided with equipment storage box (8), the experimental facility that has put cooperation fast atom bombardment ionization protein mass spectrograph (2) and use together in equipment storage box (8), fixed mounting has electric telescopic handle (9) on the back lateral wall of equipment storage box (8), electric telescopic handle (9) electric connection has the controller, the controller is used for controlling the work of electric telescopic handle (9).
2. The device for detecting the milk small-molecule bioactive peptide according to claim 1, wherein: be provided with foam pad (10) on the inner wall of equipment storage box (8), the inside of foam pad (10) is seted up with experimental facilities appearance assorted recess.
3. The device for detecting the milk small-molecule bioactive peptide according to claim 2, wherein: gravity inductor (11) are installed to the diapire of equipment storage box (8), gravity inductor (11) pass foam pad (10) and experimental facilities contact for the weight of response experimental facilities.
4. The device for detecting the milk small-molecule bioactive peptide according to claim 3, wherein: the front side of the equipment storage box (8) is provided with a transparent glass cover (12), and the transparent glass cover (12) is hinged with the top wall of the equipment storage box (8).
5. The device for detecting the milk small-molecule bioactive peptide according to claim 1, wherein: the lower part of the object placing plate (4) is further provided with a drawing plate (6), two ends of the drawing plate (6) are fixedly connected with sliding blocks, and the sliding blocks are connected in strip-shaped sliding grooves formed in the side wall of the casing (1) and the partition plate (3) in a sliding mode.
6. The device for detecting the milk small-molecule bioactive peptide according to claim 5, wherein: a plurality of special-shaped grooves are formed in the upper side face of the drawing plate (6), and the special-shaped grooves are matched with a base of the experimental equipment.
Priority Applications (1)
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CN201911196250.6A CN110865194A (en) | 2019-11-29 | 2019-11-29 | Milk small molecule bioactive peptide detection device |
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CN201911196250.6A CN110865194A (en) | 2019-11-29 | 2019-11-29 | Milk small molecule bioactive peptide detection device |
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CN110865194A true CN110865194A (en) | 2020-03-06 |
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CN201911196250.6A Pending CN110865194A (en) | 2019-11-29 | 2019-11-29 | Milk small molecule bioactive peptide detection device |
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Citations (9)
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CN101208490A (en) * | 2005-06-24 | 2008-06-25 | 张宁 | Method and system of stereo warehouse/parking and container stereo warehousing system, container terminal and method for loading and unloading operation of container terminal |
CN101520347A (en) * | 2008-02-26 | 2009-09-02 | 界鸿科技股份有限公司 | Electronic element-takeout and placing device with pressure detecting function and pressure detecting method |
CN107550347A (en) * | 2017-10-18 | 2018-01-09 | 何洁 | A kind of kitchen knife placement cabinet |
CN107969824A (en) * | 2017-12-25 | 2018-05-01 | 广州市维柏家具有限公司 | A kind of domestic intelligent shoe chest |
CN108327565A (en) * | 2018-03-20 | 2018-07-27 | 河南水天环境工程有限公司 | A kind of novel public charging pile |
CN207870604U (en) * | 2017-05-19 | 2018-09-18 | 窦丽 | A kind of medical experiment article storage box with demarcation strip |
CN207996064U (en) * | 2017-12-06 | 2018-10-23 | 齐鲁师范学院 | equipment management device |
CN208715768U (en) * | 2018-05-20 | 2019-04-09 | 孙厚杰 | A kind of Bone mineral density kit |
CN209553046U (en) * | 2019-01-10 | 2019-10-29 | 山东正泰希尔专用汽车有限公司 | A kind of intelligence pesticide residue rapid screening detection vehicle |
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2019
- 2019-11-29 CN CN201911196250.6A patent/CN110865194A/en active Pending
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101208490A (en) * | 2005-06-24 | 2008-06-25 | 张宁 | Method and system of stereo warehouse/parking and container stereo warehousing system, container terminal and method for loading and unloading operation of container terminal |
CN101520347A (en) * | 2008-02-26 | 2009-09-02 | 界鸿科技股份有限公司 | Electronic element-takeout and placing device with pressure detecting function and pressure detecting method |
CN207870604U (en) * | 2017-05-19 | 2018-09-18 | 窦丽 | A kind of medical experiment article storage box with demarcation strip |
CN107550347A (en) * | 2017-10-18 | 2018-01-09 | 何洁 | A kind of kitchen knife placement cabinet |
CN207996064U (en) * | 2017-12-06 | 2018-10-23 | 齐鲁师范学院 | equipment management device |
CN107969824A (en) * | 2017-12-25 | 2018-05-01 | 广州市维柏家具有限公司 | A kind of domestic intelligent shoe chest |
CN108327565A (en) * | 2018-03-20 | 2018-07-27 | 河南水天环境工程有限公司 | A kind of novel public charging pile |
CN208715768U (en) * | 2018-05-20 | 2019-04-09 | 孙厚杰 | A kind of Bone mineral density kit |
CN209553046U (en) * | 2019-01-10 | 2019-10-29 | 山东正泰希尔专用汽车有限公司 | A kind of intelligence pesticide residue rapid screening detection vehicle |
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Application publication date: 20200306 |