CN110423264B - 一种基于活化酯高效制备棕榈酰三肽-5的方法 - Google Patents

一种基于活化酯高效制备棕榈酰三肽-5的方法 Download PDF

Info

Publication number
CN110423264B
CN110423264B CN201910789414.XA CN201910789414A CN110423264B CN 110423264 B CN110423264 B CN 110423264B CN 201910789414 A CN201910789414 A CN 201910789414A CN 110423264 B CN110423264 B CN 110423264B
Authority
CN
China
Prior art keywords
cbz
lys
pal
val
drying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201910789414.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN110423264A (zh
Inventor
陶友华
陈金龙
王献红
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Changchun Institute of Applied Chemistry of CAS
Original Assignee
Changchun Institute of Applied Chemistry of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Changchun Institute of Applied Chemistry of CAS filed Critical Changchun Institute of Applied Chemistry of CAS
Priority to CN201910789414.XA priority Critical patent/CN110423264B/zh
Publication of CN110423264A publication Critical patent/CN110423264A/zh
Application granted granted Critical
Publication of CN110423264B publication Critical patent/CN110423264B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
CN201910789414.XA 2019-08-26 2019-08-26 一种基于活化酯高效制备棕榈酰三肽-5的方法 Active CN110423264B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910789414.XA CN110423264B (zh) 2019-08-26 2019-08-26 一种基于活化酯高效制备棕榈酰三肽-5的方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910789414.XA CN110423264B (zh) 2019-08-26 2019-08-26 一种基于活化酯高效制备棕榈酰三肽-5的方法

Publications (2)

Publication Number Publication Date
CN110423264A CN110423264A (zh) 2019-11-08
CN110423264B true CN110423264B (zh) 2020-12-01

Family

ID=68415836

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910789414.XA Active CN110423264B (zh) 2019-08-26 2019-08-26 一种基于活化酯高效制备棕榈酰三肽-5的方法

Country Status (1)

Country Link
CN (1) CN110423264B (en.​​​)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111004306B (zh) * 2019-12-31 2020-09-25 山东济肽生物科技有限公司 棕榈酰三肽-5的液相合成方法
CN113461774A (zh) * 2021-08-25 2021-10-01 深圳瑞德林生物技术有限公司 棕榈酰三肽-1的制备方法
CN114891063B (zh) * 2022-05-20 2023-06-13 浙江湃肽生物股份有限公司 一种棕榈酰三肽-1的液相合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1625150T3 (pl) * 2003-05-08 2007-05-31 Dsm Ip Assets Bv Tripeptydy i ich pochodne do stosowania w kosmetyce w celu poprawy struktury skóry
JP2015510934A (ja) * 2012-03-22 2015-04-13 プレシジョン ダーマトロジー インコーポレイテッドPrecision Dermatology, Inc. シクロデキストリンに基づくマイクロエマルション、およびその皮膚科使用
FR3052453B1 (fr) * 2016-06-14 2018-05-18 Sederma Peptide, composition le comprenant et utilisations notamment cosmetiques

Also Published As

Publication number Publication date
CN110423264A (zh) 2019-11-08

Similar Documents

Publication Publication Date Title
CN110423264B (zh) 一种基于活化酯高效制备棕榈酰三肽-5的方法
EP2231621B1 (en) Process for preparing n-substituted hydroxypyrimidinone carboxamides
EP3342777B1 (en) Benzyl compound
EP2873677A1 (en) Method of producing self-assembling peptide derivative
CN109476684A (zh) 新型呫吨保护剂
EP3412665B1 (en) Suvorexant intermediates and preparation methods thereof
CN111253287A (zh) 液相汇聚式合成索马鲁肽侧链的方法
CN103804469B (zh) 卡非佐米中间体的制备方法
CN113150066B (zh) 蓝铜胜肽的合成方法
CN104356197A (zh) 一种卡非佐米中间体及其制备方法,以及一种卡非佐米的制备方法
CN104379558B (zh) 利用谷氨酸衍生物和羟基苯胺或羟基被保护的羟基苯胺合成拉马琳以及拉马琳前体的方法
EP2247573B1 (en) Carbonic and sulphuric acid salts of 3-(2,2,2-trimethylhydrazinium)propionate esters and their use for 3-(2,2,2-trimethylhydrazinium)propionate dihydrate preparation
CN106565607B (zh) 一种l-肌肽的合成方法
CN111454180A (zh) 一种索马鲁肽侧链中间体及其制备方法
CN106946724B (zh) 单胺基抑制剂类中间体2-乙酰氨基-2-苄基丙二酸单乙酯的合成方法
CN109369779B (zh) 一种他替瑞林的合成方法
CN106146614A (zh) 一种rgd三肽的制备方法
CN105418737A (zh) 一种短瓣花环肽a的固相合成方法和应用
CN106554301B (zh) 一种沙格列汀关键中间体的制备方法
CN109824553B (zh) 2–((叔丁氧基羰基)氨基)乙基-1-磺酸及其制备方法
CN109574860A (zh) 一种制备维兰特罗的方法
CN112094224B (zh) 一种带保护基的3-取代-5-氨基哌啶的制备方法
CN113527245B (zh) 一种芦荟松的合成方法及其用途
CN107698663B (zh) 一种维洛丝肽的液相合成方法
CN111233685B (zh) 一种外消旋d/l-叔亮氨酸的制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant