CN110123887A - One group for treating the Chinese medicine of children with high fever induced convulsions - Google Patents

Abstract

The invention discloses one group for treating the Chinese medicine of children with high fever induced convulsions, to solve the problems, such as that current drug cannot eradicate children with high fever induced convulsions.It includes the substance of following parts by weight: cornu bubali 25-35g, gypsum 10-20g, rheum officinale 2-5g, radix scutellariae 3-9g, coptis 3-9g, cimicifugae foetidae 3-9g, periostracum cicada 3-9g, Oroxylum indicum 4-12g, Radix Glycyrrhizae 3-9g.The advantage of the invention is that used Chinese medicine is without side-effects, safe and reliable, curative for effect, quick, cure rate is high.

Description

One group for treating the Chinese medicine of children with high fever induced convulsions

Technical field

The invention belongs to field of medicaments, and in particular to one group for treating the Chinese medicine of children with high fever induced convulsions, signified children are 7 Year old or less children, by taking four years old children as an example.

Background technique

Children with high fever induced convulsions refer to children respiratory tract infection or other infectious diseases early stage, body temperature increase >=39 DEG C when The convulsions of generation, and exclude intracranial infection and other organic or metabolic diseases for causing to faint from fear.It is mainly shown as unexpected hair The tatanic or clonic twitches of raw whole body or local muscle group, double eyeball is stared, is squinted, sending out straight or turn over, with the loss of consciousness. Hyperpyretic convulsion is divided into pure hyperpyretic convulsion and two kinds of Complex anal fistula.Each age period (removing neonatal period) children can send out Life, pure hyperpyretic convulsion prognosis bona common with 6 months to 4 years old, Complex anal fistula prognosis are then poor.

The principle of reatment of children with high fever induced convulsions is drug application treatment and physics after detailed inspection excludes organic disease Treatment, can obtain preferable curative effect.Current clinically common drug has ibuprofen granule, C. P. P. C particle, dexamethasone Injection etc., all has certain effect, but effect is unobvious, Yi Fanfu.There are also treatment children with high fever induced convulsions on the market Although Chinese medicine, these medicines have certain curative effect, but that there is doses is big, the time is long and cannot eradicate children with high fever induced convulsions Problem.

Summary of the invention

It, cannot with the drug for solving current the object of the present invention is to provide one group for treating the Chinese medicine of children with high fever induced convulsions The problem of eradicating children with high fever induced convulsions.

Technical scheme is as follows: one group for treating the Chinese medicine of children with high fever induced convulsions, by the original of following parts by weight Material composition: cornu bubali 25-35g, gypsum 10-20g, rheum officinale 2-5g, radix scutellariae 3-9g, coptis 3-9g, cimicifugae foetidae 3-9g, periostracum cicada 3-9g, Oroxylum indicum 4-12g, Radix Glycyrrhizae 3-9g.

Preferably, the parts by weight group of each raw material becomes, and cornu bubali 30g, gypsum 15g, rheum officinale 3g, radix scutellariae 6g, coptis 6g, rises Numb 6g, periostracum cicada 6g, Oroxylum indicum 8g, Radix Glycyrrhizae 6g.

Said medicine preparation process is as follows: by material medicine cornu bubali, gypsum, rheum officinale, radix scutellariae, the coptis, cimicifugae foetidae, periostracum cicada, Oroxylum indicum, Radix Glycyrrhizae, are respectively prepared medicine materical crude slice, by pressure cooker cooking disinfection 30-45 minutes, dry, and obtain aseptic raw material, then Chinese materia medica preparation, which is made, in aseptic raw material to take.

Cornu bubali, gypsum have clearing heat and detoxicating, cool blood in the present invention, and arresting convulsion, purge heat logical intestines, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow For monarch drug in a prescription.Rheum officinale, radix scutellariae, the coptis are purged heat logical intestines, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, except damp and hot, hemostasis, heat-clearing and damp-drying drug, purging fire for removing toxin For ministerial drug.Cimicifugae foetidae, periostracum cicada, Oroxylum indicum deliver promoting eruption, clearing heat and detoxicating, yang invigorating, and relieve heat moves back screen except heat, relieving sore-throat, promoting eruption, solve Convulsion, removing heat from the lung and relieving sorethroat, soothing liver and harmonizing stomach are adjutant.Radix Glycyrrhizae is invigorated the spleen and benefited qi, moistening lung to arrest cough, clearing heat and detoxicating, alleviates analgesic, and coordinating the drug actions of a prescription is Make medicine.

The pharmacological property and its effect of each component of the present invention are as follows:

Cornu bubali, it is bitter, it trembles with fear, converge to heart and liver channels.Major function: clearing heat and detoxicating, cool blood, arresting convulsion.The major functions: warm disease high fever, coma are raved Language, spot dermexanthesis, hematemesis and epistaxis, infantile convulsion are demented.

Rheum officinale: it is bitter, it trembles with fear, returns spleen, stomach, large intestine, liver, pericardium channel.Major function: the logical intestines that purge heat, removing pattogenic heat from the blood and toxic material from the body is logical by the stasis of blood Through.The major functions: real heat constipation, stagnate abdominal pain, and dysentery is not well, jaundice with damp-heat pathogen, blood-head tells nosebleed, hot eyes, pharynx swelling, abdominalgia with intestinal abscess, carbuncle swells Furunculosis, blood stasis closed, traumatic injury control scald outside；Upper gastrointestinal bleeding.Rheum palmatum (processed with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For Hot eyes pharynx swelling, gingivitis.Prepared RADIX ET RHIZOMA RHEI, which rushes down, to be exerted oneself to delay, purging fire for removing toxin.For pathogenic fire,toxin and furuncles.The hemostasis of charred RADIX ET RHIZOMA RHEI cooling blood and removing stasis.With There is stasis of blood haemorrhage in blood-head.

Gypsum, pungent, sweet, Great Cold.It attaches to the lung and stomach meridians.Major function: clearing heat-fire, relieving restlessness cough-relieving.The major functions: fever caused by exogenous pathogenic factors, high Re Fan section, dyspnea and cough due to lung-heat, stomach fire Kang Sheng have a headache, toothache.Calcined gypsum convergence, myogenic, sore, hemostasis.Ulcer pyreticosis is controlled outside, it is wet Rash itching, scald, traumatic hemorrhage.

Radix scutellariae, meridian distribution of property and flavor: cold in nature, bitter, return heart, lung, gallbladder, large intestine channel.Major function: rush down excess fire, except damp and hot, only Blood, miscarriage prevention.The major functions: high fever polydipsia, cough with lung heat, damp-heat dysentery, jaundice, heat gonorrhea, red eye, swell pain, threatened abortion, carbuncle swells furunculosis.

The coptis, cold in nature, bitter, return heart, spleen, stomach, liver, gallbladder, large intestine channel.Major function: heat-clearing and damp-drying drug, purging fire for removing toxin.It is main It controls: damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, palpitation and uneasiness, blood-head tells nosebleed, Hot eyes, toothache, quenches one's thirst, and carbuncle swells treat sore；Eczema, wet sore, purulent ear canal are controlled outside.

Cimicifugae foetidae, meridian distribution of property and flavor: cold nature, acrid flavour, sweet, return lung, spleen, large intestine, stomach meridian.Major function: promoting eruption is delivered, heat-clearing Removing toxic substances, yang invigorating.The major functions: when gas plague, fever and chills of having a headache, laryngalgia, aphtha, macula is impermeable；The sinking of qi of middle-jiao, protracted dysentery and diarrhea take off Anus, women collapses, band, uterus tenesmus；Carbuncle sore tumefacting virus.

Periostracum cicada, it is sweet, it trembles with fear, return lung, Liver Channel.Major function: relieve heat, except heat, relieving sore-throat, promoting eruption moves back screen, spasmolysis.The major functions: wind-heat Flu, pharyngalgia, hoarse voice, measles without adequate eruption, rubella itch, cataract, convulsion, tetanus.

Oroxylum indicum: bitter, sweet, cool, return lung, liver, stomach meridian.Major function: removing heat from the lung and relieving sorethroat, soothing liver and harmonizing stomach.The major functions: lung heat cough It coughs, sore throat, hoarse voice, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.Premature ejaculation, small yin channel, impotence, irregular menstruation.

Radix Glycyrrhizae, mild-natured, sweet in flavor, return 12 warps.Major function: invigorating the spleen and benefiting qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, emergency is stopped Bitterly, coordinating the drug actions of a prescription.The major functions: weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle swells sore Poison alleviates drug toxicity, strong.

The Chinese medicine that the present invention treats children with high fever induced convulsions has clearing heat and detoxicating, cool blood, and arresting convulsion, purge heat logical intestines, removing pattogenic heat from the blood and toxic material from the body, Dispelling stasis of blood and stimulating the menstrual flow, purge heat logical intestines, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, and except damp and hot, hemostasis, heat-clearing and damp-drying drug, purging fire for removing toxin delivers promoting eruption, clearly Thermal detoxification, yang invigorating, relieve heat move back screen except heat, relieving sore-throat, promoting eruption, spasmolysis, removing heat from the lung and relieving sorethroat, and soothing liver and harmonizing stomach is invigorated the spleen and benefited qi, moistening lung Cough-relieving, it is clearing heat and detoxicating, alleviate the effect of analgesic, and significant in efficacy, quick, securely and reliably, no obvious toxic-side effects can be effective Treat children with high fever induced convulsions.

Specific embodiment

The following examples can further illustrate the present invention, but do not limit the invention in any way.

Embodiment 1, the drug for treating children with high fever induced convulsions form: cornu bubali 30g, gypsum 15g, rheum officinale 3g, radix scutellariae 6g, coptis 6g, cimicifugae foetidae 6g, periostracum cicada 6g, Oroxylum indicum 8g, Radix Glycyrrhizae 6g.The present embodiment effect is best.

Embodiment 2, the drug for treating children with high fever induced convulsions form: cornu bubali 35, gypsum 20g, rheum officinale 6g, radix scutellariae 9g, coptis 9g, cimicifugae foetidae 9g, periostracum cicada 9g, Oroxylum indicum 12g, Radix Glycyrrhizae 9g.The present embodiment drug effect is stronger.

Embodiment 3, the drug for treating children with high fever induced convulsions form: cornu bubali 25g, gypsum 10g, rheum officinale 2g, radix scutellariae 3g, coptis 3g, cimicifugae foetidae 3g, periostracum cicada 3g, Oroxylum indicum 4g, Radix Glycyrrhizae 3g.Embodiment drug effect is slightly weak.

It is the following cornu bubali of above-described embodiment preparation process, gypsum, rheum officinale, radix scutellariae, the coptis, cimicifugae foetidae, periostracum cicada, Oroxylum indicum, sweet Medicine materical crude slice is respectively prepared in grass, by pressure cooker cooking disinfection 30-45 minutes, dries, and obtains aseptic raw material, then by sterile former material Chinese materia medica preparation, which is made, in material to take, and in each 1 time of daily evening in morning, 3 as a treatment course.

" clinical trial "

For the curative effect for showing drug of the present invention, 300 patients for being diagnosed as children with high fever induced convulsions are taken, cardinal symptom is body temperature liter It is high >=39 DEG C, the tatanic or clonic twitches of the whole body occurred suddenly or local muscle group, double eyeball stares, squints, send out directly or It turns over, with symptoms such as the loss of consciousness.

It is divided into two groups to be treated, wherein one group is control group, one group is observation group, and two groups of cases each 150, two groups sick Example is at the age, and gender, illness weight etc. is without comparativity.Control group is used to ibuprofen granule by specification, is within 3rd One course for the treatment of treats the 2-6 course for the treatment of；Drug made from observation group's one after each meal embodiment of the present invention 1, once in the morning and once at night, 3 are one The course for the treatment of treats the 2-6 course for the treatment of.Two groups with cardinal symptom: body temperature increases >=39 DEG C, the whole body occurred suddenly or local muscle group Tatanic or clonic twitches, double eyeball stares, squints, it is straight to send out or turns over, be with the mitigation of the symptoms such as loss of consciousness it is effective, with Cardinal symptom: body temperature raising >=39 DEG C, the tatanic or clonic twitches of the whole body occurred suddenly or local muscle group, double eyeball coagulates Depending on, strabismus, hair is straight or turns over, disappear with symptoms such as loss of consciousness for recovery from illness.Vertical shelves, which stay to look into, is subject to Statistical Comparison, and statistics shows to tie Fruit is shown in Table 1(control group curative effect situation) and table 2(experimental group curative effect situation), by the comparison to control group and experimental group, this hair The effect of bright drug therapy children with high fever induced convulsions is substantially better than the effect of ibuprofen granule.Medication effect of the present invention: effectively Rate: 94.7%, cure rate 90%.

Table 1

Table 2

" typical case ":

1, Chen, male, 3 years old, body temperature raising >=39 DEG C, there is the tatanic or clonicity of the whole body occurred suddenly or local muscle group Twitch, double eyeball was stared, is squinted, sending out straight or turn over, with loss of consciousness etc. symptoms 3 months repeatedly.Using medicine of the present invention Object is treated, and in each 1 time of daily evening in morning, 3 are as a treatment course, after 2 courses for the treatment of are used in conjunction, body temperature raising >=39 DEG C, there is hair suddenly The tatanic or clonic twitches of raw whole body or local muscle group, double eyeball is stared, is squinted, sending out straight or turn over, with the loss of consciousness Etc. symptoms gradually mitigate, after 3 courses for the treatment of, body temperature increased >=39 DEG C, there is the tatanic of the whole body that occurs suddenly or local muscle group Or clonic twitches, double eyeball are stared, are squinted, sending out straight or turn over, disappearing with symptoms such as the loss of consciousness.It is further continued for taking 2 treatments Cheng Tian is to consolidate curative effect, and follow-up 2 years without recurrence.

2, Cao, female, 4 years old, occur repeatedly body temperature raising >=39 DEG C, there is the strong of the whole body that occurs suddenly or local muscle group Straightforward or clonic twitches, double eyeball was stared, is squinted, sending out straight or turn over, with loss of consciousness etc. symptoms 1 month repeatedly.Using this The invention drug is treated, and in each 1 time of daily evening in morning, 3 are as a treatment course, after 3 courses for the treatment of are used in conjunction, body temperature raising >=39 DEG C, there are the tatanic or clonic twitches of the whole body that occurs suddenly or local muscle group, double eyeball stares, squints, send out directly or on It turns over, gradually mitigates with symptoms such as the loss of consciousness, after 4 courses for the treatment of, body temperature raising >=39 DEG C, there is the whole body occurred suddenly or part The tatanic or clonic twitches of muscle group, double eyeball are stared, are squinted, sending out straight or turn over, disappearing with symptoms such as the loss of consciousness.Followed by Continuous to take 2 course for the treatment of day to consolidate curative effect, follow-up 2 years without recurrence.

Claims (2)

1. one group for treating the Chinese medicine of children with high fever induced convulsions, it is characterised in that it is made of the raw material of following parts by weight: buffalo Angle 25-35g, gypsum 10-20g, rheum officinale 2-5g, radix scutellariae 3-9g, coptis 3-9g, cimicifugae foetidae 3-9g, periostracum cicada 3-9g, Oroxylum indicum 4-12g, Radix Glycyrrhizae 3-9g.

2. the Chinese medicine for being used to treat children with high fever induced convulsions according to claim 1, it is characterised in that: the weight of each raw material Part group becomes, cornu bubali 30g, gypsum 15g, rheum officinale 3g, radix scutellariae 6g, coptis 6g, cimicifugae foetidae 6g, periostracum cicada 6g, Oroxylum indicum 8g, Radix Glycyrrhizae 6g。